KNApSAcK Metabolite C00016936
Metabolite
KNApSAcK Entry
| id | C00016936 |
|---|---|
| Name | Myriocin / Thermozymocidin |
| CAS RN | 35891-70-4 |
| Standard InChI | InChI=1S/C21H39NO6/c1-2-3-4-10-13-17(24)14-11-8-6-5-7-9-12-15-18(25)19(26)21(22,16-23)20(27)28/h9,12,18-19,23,25-26H,2-8,10-11,13-16,22H2,1H3,(H,27,28)/b12-9+/t18-,19+,21+/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C21H39NO6/c1-2-3-4-10-13-17(24)14-11-8-6-5-7-9-12-15-18(25)19(26)21(22,16-23)20(27)28/h9,12,18-19,23,25-26H,2-8,10-11,13-16,22H2,1H3,(H,27,28) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 942 |
Link
ChEMBL
| By standard InChI | CHEMBL55076 |
|---|---|
| By standard InChI Main Layer | CHEMBL55076 |
KEGG
| By LinkDB | C19914 |
|---|
CTD
| By CAS RN | C001996 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Ophiocordycipitaceae | 1 |
List (3)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Cordyceps heteropoda | 94212 | Ophiocordycipitaceae | Fungi | |
| Isaria Sinclairii ATCC 24400 | ||||
| Myriococcum albomyces MRRL 3858 | 455372 | Fungi |
Human Protein / Gene in interaction
2 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P37268 | Squalene synthase | Enzyme | CHEMBL55076 |
CHEMBL1244173
(1)
|
0 / 0 |
| P31749 | RAC-alpha serine/threonine-protein kinase | Akt | CHEMBL55076 |
CHEMBL1244167
(1)
CHEMBL1244168
(1)
|
4 / 1 |
CTD interaction (5)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C001996 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | thermozymocidin inhibits the reaction [Dronabinol results in increased activity of CASP3 protein] |
decreases reaction
/ increases activity |
protein |
16818650
|
| C001996 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | thermozymocidin inhibits the reaction [gamma-Tocopherol results in increased activity of CASP3 protein] |
decreases reaction
/ increases activity |
protein |
15596715
|
| C001996 | 355 |
FAS
ALPS1A APO-1 APT1 CD95 FAS1 FASTM TNFRSF6 |
Fas cell surface death receptor | thermozymocidin inhibits the reaction [[sorafenib co-treated with vorinostat] affects the localization of and results in increased activity of FAS protein] |
affects cotreatment
/ affects localization / decreases reaction / increases activity |
protein |
18787411
|
| C001996 | 26471 |
NUPR1
COM1 P8 |
nuclear protein, transcriptional regulator, 1 | thermozymocidin inhibits the reaction [Dronabinol results in increased expression of NUPR1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
16818650
|
| C001996 | 4953 |
ODC1
ODC |
ornithine decarboxylase 1 (EC:4.1.1.17) | thermozymocidin inhibits the reaction [resveratrol results in decreased activity of ODC1 protein] |
decreases activity
/ decreases reaction |
protein |
17521618
|