PCIDB

KNApSAcK Metabolite C00001712

Index

Metabolite

Species

Human Protein
/ Gene in interactions

Related Diseases

Metabolite

KNApSAcK Entry

id	C00001712
Name	Deserpidine
CAS RN	131-01-1
Standard InChI	InChI=1S/C32H38N2O8/c1-37-24-12-17(13-25(38-2)29(24)39-3)31(35)42-26-14-18-16-34-11-10-20-19-8-6-7-9-22(19)33-28(20)23(34)15-21(18)27(30(26)40-4)32(36)41-5/h6-9,12-13,18,21,23,26-27,30,33H,10-11,14-16H2,1-5H3/t18-,21+,23-,26-,27+,30+/m1/s1
Standard InChI (Main Layer)	InChI=1S/C32H38N2O8/c1-37-24-12-17(13-25(38-2)29(24)39-3)31(35)42-26-14-18-16-34-11-10-20-19-8-6-7-9-22(19)33-28(20)23(34)15-21(18)27(30(26)40-4)32(36)41-5/h6-9,12-13,18,21,23,26-27,30,33H,10-11,14-16H2,1-5H3

Cluster

Phytochemical cluster	No. 4
KCF-S cluster	No. 2040

Link

ChEMBL

By standard InChI	CHEMBL1200515
By standard InChI Main Layer	CHEMBL1200515

KEGG

By LinkDB	C06541

CTD

By CAS RN	C100104

Species

Summary

Plant class

class name	count
asterids	5

Family

family name	count
Apocynaceae	5

List (6)

* NCBI

KNApSAcK organism	*ID	*family	*plant class	*kingdom
Rauvolfia canescens	4059	Apocynaceae	asterids	Viridiplantae
Rauvolfia cubana	4059	Apocynaceae	asterids	Viridiplantae
Rauvolfia littoralis	681485	Apocynaceae	asterids	Viridiplantae
Rauwolfia canescens	4059	Apocynaceae	asterids	Viridiplantae
Rauwolfia nitida Jacq.	4059	Apocynaceae	asterids	Viridiplantae
Tonduza longifolia

Human Protein / Gene in interaction

8 ChEMBL Protein in interactions

accession	description	class description	compound	assay ID (# of activities)	# of diseases (OMIM / KEGG)
P11473	Vitamin D3 receptor	NR1I1	CHEMBL1200515	CHEMBL1794311 (1)	2 / 3
Q92830	Histone acetyltransferase KAT2A	Enzyme	CHEMBL1200515	CHEMBL1738606 (1)	0 / 0
O75496	Geminin	Unclassified protein	CHEMBL1200515	CHEMBL2114780 (1)	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	CHEMBL1200515	CHEMBL1794467 (1)	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	CHEMBL1200515	CHEMBL1794536 (1)	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	CHEMBL1200515	CHEMBL1738442 (1)	0 / 0
O00255	Menin	Unclassified protein	CHEMBL1200515	CHEMBL1614531 (1)	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	CHEMBL1200515	CHEMBL1614531 (1)	1 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM	preferred title	UniProt
#605130	Hairy elbows, short stature, facial dysmorphism, and developmental delay	Q03164
#145000	Hyperparathyroidism 1; hrpt1	O00255
#131100	Multiple endocrine neoplasia, type i; men1	O00255
#607948	Mycobacterium tuberculosis, susceptibility to	P11473
#277440	Vitamin d-dependent rickets, type 2a; vddr2a	P11473

KEGG DISEASE (10)

KEGG	disease name	UniProt
H00033	Adrenal carcinoma	O00255 (related)
H00034	Carcinoid	O00255 (related)
H00045	Malignant islet cell carcinoma	O00255 (related)
H00246	Primary hyperparathyroidism	O00255 (related)
H01102	Pituitary adenomas	O00255 (related)
H00342	Tuberculosis	P11473 (related)
H00784	Localized autosomal recessive hypotrichosis	P11473 (related)
H01143	Vitamin D-dependent rickets	P11473 (related)
H00001	Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)	Q03164 (related) Q03164 (marker)
H00002	Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)	Q03164 (related)