PCIDB

KNApSAcK Metabolite C00018028

Metabolite

KNApSAcK Entry

id C00018028
Name Lysocellin
CAS RN 55898-33-4
Standard InChI InChI=1S/C34H60O10/c1-11-24(28(39)22(8)27(38)23(9)29-18(4)14-20(6)33(40,43-29)17-26(36)37)30-19(5)15-31(10,42-30)34(41)21(7)16-32(13-3,44-34)25(35)12-2/h18-25,27,29-30,35,38,40-41H,11-17H2,1-10H3,(H,36,37)/t18-,19-,20+,21+,22-,23-,24-,25-,27+,29-,30-,31-,32+,33-,34+/m0/s1
Standard InChI (Main Layer) InChI=1S/C34H60O10/c1-11-24(28(39)22(8)27(38)23(9)29-18(4)14-20(6)33(40,43-29)17-26(36)37)30-19(5)15-31(10,42-30)34(41)21(7)16-32(13-3,44-34)25(35)12-2/h18-25,27,29-30,35,38,40-41H,11-17H2,1-10H3,(H,36,37)

Cluster

Phytochemical cluster
KCF-S cluster No. 1446

Link

ChEMBL

By standard InChI
By standard InChI Main Layer

KEGG

By LinkDB

CTD

By CAS RN C009818

Species

Summary

Plant class

class name count

Family

family name count
Streptomycetaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Streptomyces cacaoi var. asoensis K-9 Met- 1883 Streptomycetaceae Bacteria

Human Protein / Gene in interaction

CTD interaction (5)

compound gene gene name gene description interaction interaction type form reference
pmid
C009818 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [lysocellin results in decreased expression of CCND1 protein] decreases expression
/ decreases reaction
protein 16525630
C009818 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 lysocellin results in decreased expression of CCND1 mRNA decreases expression
mRNA 16525630
C009818 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 lysocellin results in decreased expression of CCND1 protein decreases expression
protein 16525630
C009818 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) lysocellin results in increased expression of CDKN1A mRNA increases expression
mRNA 16525630
C009818 5925 RB1
OSRC
RB
p105-Rb
pRb
pp110
retinoblastoma 1 lysocellin results in decreased phosphorylation of RB1 protein decreases phosphorylation
protein 16525630