PCIDB

KNApSAcK Metabolite C00018127

Metabolite

KNApSAcK Entry

id C00018127
Name AM-2282 / CGP 39360 / Staurosporin / Staurosporine / Antibiotic 230 / (+)-Staurosporine / Antibiotic AM 2282
CAS RN 62996-74-1
Standard InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1
Standard InChI (Main Layer) InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)

Cluster

Phytochemical cluster
KCF-S cluster No. 251

Link

ChEMBL

By standard InChI CHEMBL388978
By standard InChI Main Layer CHEMBL290084 CHEMBL162 CHEMBL364347 CHEMBL388978 CHEMBL1537489 CHEMBL1709437 CHEMBL1979949 CHEMBL1980995

KEGG

By LinkDB C02079

CTD

By CAS RN D019311

Species

Summary

Plant class

class name count

Family

family name count
Streptomycetaceae 20
Polycitoridae 1
Micromonosporaceae 1

List (23)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Eudistoma toealensis 286195 Polycitoridae Metazoa
Micromonospora sp. L-31-CLCO-002 (CECT3347) 1873 Micromonosporaceae Bacteria
Saccharothrix aerocolonigenes subsp. copiosa SCC1951
Streptomyces actuosus 1885 Streptomycetaceae Bacteria
Streptomyces hygroscopicus C39280-450-9 (ATCC53730) 1883 Streptomycetaceae Bacteria
Streptomyces lividus ATCC21178 1883 Streptomycetaceae Bacteria
Streptomyces longisporoflavus 28044 Streptomycetaceae Bacteria
Streptomyces longisporoflavus R-19 (DSM10189) 1883 Streptomycetaceae Bacteria
Streptomyces platensis subsp. malvinus RK-1409 1883 Streptomycetaceae Bacteria
Streptomyces sp .N-128 1883 Streptomycetaceae Bacteria
Streptomyces sp. AB1869R-359 (NRRL B-16735) 1883 Streptomycetaceae Bacteria
Streptomyces sp. AM-2282 1883 Streptomycetaceae Bacteria
Streptomyces sp. C-71799 1883 Streptomycetaceae Bacteria
Streptomyces sp. KS3 1883 Streptomycetaceae Bacteria
Streptomyces sp. M-193 1883 Streptomycetaceae Bacteria
Streptomyces sp. N-115 1883 Streptomycetaceae Bacteria
Streptomyces sp. N-126 1883 Streptomycetaceae Bacteria
Streptomyces sp. N-129 1883 Streptomycetaceae Bacteria
Streptomyces sp. N-71 1883 Streptomycetaceae Bacteria
Streptomyces sp. N96C-47 1883 Streptomycetaceae Bacteria
Streptomyces sp. RK-286 1883 Streptomycetaceae Bacteria
Streptomyces sp. TP-A0274 171258 Streptomycetaceae Bacteria
Streptomyces staurosporeus AM-2282 1883 Streptomycetaceae Bacteria

Human Protein / Gene in interaction

451 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P42345 Serine/threonine-protein kinase mTOR Enzyme CHEMBL162 CHEMBL1908669 (1) CHEMBL2219345 (1)
CHEMBL2219346 (1) CHEMBL2219347 (1)
CHEMBL2219348 (1)
0 / 0
Q02750 Dual specificity mitogen-activated protein kinase kinase 1 Ste7 CHEMBL162 CHEMBL388978 CHEMBL1980995 CHEMBL731425 (1) CHEMBL731428 (1)
CHEMBL769165 (1) CHEMBL1064038 (1)
CHEMBL1061906 (1) CHEMBL1286032 (1)
CHEMBL1286033 (1) CHEMBL1614327 (1)
CHEMBL1908590 (1) CHEMBL1919764 (1)
CHEMBL1963692 (1) CHEMBL2219261 (1)
CHEMBL2219262 (1)
1 / 1
P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Enzyme CHEMBL162 CHEMBL1908743 (1)
0 / 0
Q32MK0 Myosin light chain kinase 3 Mlck CHEMBL162 CHEMBL1908435 (1)
0 / 0
P36897 TGF-beta receptor type-1 TKL dual-specificity kinase STKR type 1 subfamily CHEMBL162 CHEMBL1051314 (1) CHEMBL1908658 (1)
CHEMBL2219207 (1) CHEMBL2219208 (1)
CHEMBL2328424 (1)
3 / 2
Q2M2I8 AP2-associated protein kinase 1 NAK serine/threonine protein kinase subfamily CHEMBL162 CHEMBL860786 (1) CHEMBL1037546 (1)
CHEMBL1908786 (1)
0 / 0
Q13555 Calcium/calmodulin-dependent protein kinase type II subunit gamma Camk2 CHEMBL162 CHEMBL657561 (1) CHEMBL653818 (1)
CHEMBL767435 (1) CHEMBL861045 (1)
CHEMBL1061137 (1) CHEMBL1908428 (1)
CHEMBL2219012 (1) CHEMBL2219013 (1)
0 / 0
P29322 Ephrin type-A receptor 8 Eph CHEMBL162 CHEMBL860777 (1) CHEMBL1063708 (1)
CHEMBL1908817 (1) CHEMBL2219048 (1)
CHEMBL2219049 (1)
0 / 0
P42685 Tyrosine-protein kinase FRK Src CHEMBL162 CHEMBL860775 (1) CHEMBL1060247 (1)
CHEMBL1908552 (1) CHEMBL2219131 (1)
CHEMBL2219132 (1)
0 / 0
P49759 Dual specificity protein kinase CLK1 Clk CHEMBL162 CHEMBL860774 (1) CHEMBL1050838 (1)
CHEMBL1908461 (1)
0 / 0
Q13043 Serine/threonine-protein kinase 4 STE serine/threonine protein kinase MST subfamily CHEMBL162 CHEMBL860661 (1) CHEMBL1061178 (1)
CHEMBL1908752 (1) CHEMBL2219285 (1)
CHEMBL2219286 (1)
1 / 0
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim CHEMBL162 CHEMBL1980995 CHEMBL859489 (1) CHEMBL931462 (1)
CHEMBL960129 (1) CHEMBL960130 (1)
CHEMBL1061184 (1) CHEMBL1908761 (1)
CHEMBL1963820 (1) CHEMBL2219137 (1)
CHEMBL2219138 (1)
0 / 0
Q8TDX7 Serine/threonine-protein kinase Nek7 Nek CHEMBL162 CHEMBL1063808 (1) CHEMBL1908451 (1)
CHEMBL2219353 (1) CHEMBL2219354 (1)
0 / 0
Q5VT25 Serine/threonine-protein kinase MRCK alpha AGC serine/threonine protein kinase GEK subfamily CHEMBL162 CHEMBL1980995 CHEMBL1060251 (1) CHEMBL1908617 (1)
CHEMBL1964102 (1) CHEMBL2219275 (1)
CHEMBL2219276 (1)
0 / 0
Q08345 Epithelial discoidin domain-containing receptor 1 Ddr CHEMBL162 CHEMBL1050825 (1) CHEMBL1908547 (1)
0 / 0
Q14289 Protein-tyrosine kinase 2-beta Fak CHEMBL162 CHEMBL1061158 (1) CHEMBL1908429 (1)
CHEMBL2219147 (1) CHEMBL2219148 (1)
0 / 0
P08922 Proto-oncogene tyrosine-protein kinase ROS TK tyrosine-protein kinase SEV CHEMBL162 CHEMBL1980995 CHEMBL1057208 (1) CHEMBL1061925 (1)
CHEMBL1908596 (1) CHEMBL1919771 (1)
CHEMBL1963751 (1) CHEMBL2219159 (1)
CHEMBL2219160 (1)
0 / 1
Q15831 Serine/threonine-protein kinase STK11 Lkb CHEMBL162 CHEMBL1051288 (1) CHEMBL1908495 (1)
CHEMBL2219241 (1) CHEMBL2219242 (1)
2 / 2
Q59H18 Serine/threonine-protein kinase TNNI3K HH498 CHEMBL162 CHEMBL1061932 (1) CHEMBL1908794 (1)
0 / 0
Q8N752 Casein kinase I isoform alpha-like Ck1-a CHEMBL162 CHEMBL1063703 (1) CHEMBL1908420 (1)
0 / 0
Q8WXR4 Myosin-IIIb STE serine/threonine protein kinase NINAC subfamily CHEMBL162 CHEMBL1060259 (1) CHEMBL1908514 (1)
0 / 0
P49336 Cyclin-dependent kinase 8 Cdk8 CHEMBL162 CHEMBL1980995 CHEMBL1051283 (1) CHEMBL1908526 (1)
CHEMBL1963824 (1)
0 / 0
Q96Q40 Cyclin-dependent kinase 15 Pftaire CHEMBL162 CHEMBL1908415 (1)
0 / 0
Q04771 Activin receptor type-1 TKL serine/threonine protein kinase STKR1 subfamily CHEMBL162 CHEMBL1980995 CHEMBL1063697 (1) CHEMBL1908516 (1)
CHEMBL1963721 (1)
1 / 2
Q16637 Survival motor neuron protein Unclassified protein CHEMBL1537489 CHEMBL1613842 (1)
4 / 2
P17861 X-box-binding protein 1 Unclassified protein CHEMBL1537489 CHEMBL1738682 (1)
1 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL388978 CHEMBL1794499 (1)
2 / 0
O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Enzyme CHEMBL162 CHEMBL1908448 (1)
1 / 1
Q9BYP7 Serine/threonine-protein kinase WNK3 WNK serine/threonine protein kinase subfamily CHEMBL162 CHEMBL2219329 (1) CHEMBL2219330 (1)
0 / 0
Q56UN5 Mitogen-activated protein kinase kinase kinase 19 STE serine/threonine protein kinase MEKK15 subfamily CHEMBL162 CHEMBL1908833 (1)
0 / 0
Q8NE63 Homeodomain-interacting protein kinase 4 CMGC serine/threonine protein kinase HIPK subfamily CHEMBL162 CHEMBL1908417 (1)
0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) CHEMBL162 CHEMBL827947 (1)
2 / 2
P08069 Insulin-like growth factor 1 receptor TK tyrosine-protein kinase INSR subfamily CHEMBL162 CHEMBL1980995 CHEMBL699144 (1) CHEMBL901550 (1)
CHEMBL1061075 (1) CHEMBL1211282 (1)
CHEMBL1764698 (1) CHEMBL1764699 (1)
CHEMBL1764700 (1) CHEMBL1764701 (1)
CHEMBL1908497 (1) CHEMBL1919758 (1)
CHEMBL1963792 (1) CHEMBL2219110 (1)
CHEMBL2219111 (1) CHEMBL2219209 (1)
CHEMBL2219210 (1)
1 / 3
Q15759 Mitogen-activated protein kinase 11 p38 CHEMBL162 CHEMBL732633 (1) CHEMBL860916 (1)
CHEMBL1062864 (1) CHEMBL1908587 (1)
CHEMBL2219173 (1) CHEMBL2219174 (1)
0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 CHEMBL162 CHEMBL1980995 CHEMBL732633 (1) CHEMBL860914 (1)
CHEMBL973451 (1) CHEMBL1061091 (1)
CHEMBL1050681 (1) CHEMBL1050682 (1)
CHEMBL1220468 (1) CHEMBL1908411 (1)
CHEMBL1964117 (1) CHEMBL2219171 (1)
CHEMBL2219172 (1) CHEMBL2343189 (1)
0 / 0
P06746 DNA polymerase beta Enzyme CHEMBL1537489 CHEMBL1614079 (1)
0 / 0
P21802 Fibroblast growth factor receptor 2 TK tyrosine-protein kinase TLK subfamily CHEMBL162 CHEMBL676887 (1) CHEMBL860912 (1)
CHEMBL972539 (1) CHEMBL1048161 (1)
CHEMBL1908828 (1) CHEMBL1921576 (1)
CHEMBL2219064 (1) CHEMBL2219065 (1)
9 / 3
Q13163 Dual specificity mitogen-activated protein kinase kinase 5 Ste7 CHEMBL162 CHEMBL1286034 (1) CHEMBL1286035 (1)
CHEMBL1908418 (1)
0 / 0
O15530 3-phosphoinositide-dependent protein kinase 1 Pdk1 CHEMBL162 CHEMBL1980995 CHEMBL1061922 (1) CHEMBL1908573 (1)
CHEMBL1963821 (1) CHEMBL2219388 (1)
CHEMBL2219389 (1)
0 / 0
Q9UIK4 Death-associated protein kinase 2 Dapk CHEMBL162 CHEMBL860909 (1) CHEMBL1053760 (1)
CHEMBL1908774 (1) CHEMBL2219022 (1)
CHEMBL2219023 (1)
0 / 0
P41240 Tyrosine-protein kinase CSK Csk CHEMBL162 CHEMBL860907 (1) CHEMBL900480 (1)
CHEMBL1037547 (1) CHEMBL1908645 (1)
CHEMBL2219006 (1) CHEMBL2219007 (1)
0 / 0
Q13237 cGMP-dependent protein kinase 2 Pkg CHEMBL162 CHEMBL1051256 (1) CHEMBL1908750 (1)
0 / 0
Q16816 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Phk CHEMBL162 CHEMBL765147 (1) CHEMBL860897 (1)
CHEMBL1061153 (1) CHEMBL1908732 (1)
0 / 0
P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Enzyme CHEMBL162 CHEMBL1050831 (1) CHEMBL1060260 (1)
CHEMBL1817211 (1) CHEMBL1908733 (1)
CHEMBL1908734 (1) CHEMBL1908735 (1)
CHEMBL1908736 (1) CHEMBL1908737 (1)
CHEMBL1908738 (1) CHEMBL1908739 (1)
CHEMBL1908740 (1) CHEMBL1908741 (1)
CHEMBL1908742 (1)
9 / 1
P45984 Mitogen-activated protein kinase 9 Jnk CHEMBL162 CHEMBL1980995 CHEMBL860895 (1) CHEMBL1060196 (1)
CHEMBL1908414 (1) CHEMBL1963746 (1)
CHEMBL2219233 (1) CHEMBL2219234 (1)
0 / 0
P17252 Protein kinase C alpha type Alpha CHEMBL162 CHEMBL760364 (1) CHEMBL767704 (1)
CHEMBL767029 (1) CHEMBL767037 (1)
CHEMBL767225 (1) CHEMBL769345 (1)
CHEMBL769348 (1) CHEMBL769354 (1)
CHEMBL766548 (1) CHEMBL772645 (1)
CHEMBL767434 (1) CHEMBL767441 (1)
CHEMBL767445 (1) CHEMBL768516 (1)
CHEMBL827792 (1) CHEMBL827979 (1)
CHEMBL860891 (1) CHEMBL868613 (1)
CHEMBL973457 (1) CHEMBL1768515 (1)
CHEMBL2219398 (1) CHEMBL2219399 (1)
0 / 0
Q16512 Serine/threonine-protein kinase N1 Pkn CHEMBL162 CHEMBL1051253 (1) CHEMBL1908442 (1)
0 / 0
P27361 Mitogen-activated protein kinase 3 Erk CHEMBL162 CHEMBL868619 (1) CHEMBL972536 (1)
CHEMBL963405 (1) CHEMBL1064039 (1)
CHEMBL1037552 (1) CHEMBL1211286 (1)
CHEMBL1908582 (1) CHEMBL2219251 (1)
CHEMBL2219252 (1) CHEMBL2343185 (1)
0 / 0
Q15349 Ribosomal protein S6 kinase alpha-2 Rskb CHEMBL162 CHEMBL860804 (1) CHEMBL1062786 (1)
CHEMBL1060342 (1) CHEMBL1908502 (1)
CHEMBL1908824 (1) CHEMBL2219167 (1)
CHEMBL2219168 (1)
0 / 0
P04629 High affinity nerve growth factor receptor Trk CHEMBL162 CHEMBL1980995 CHEMBL860803 (1) CHEMBL901559 (1)
CHEMBL973466 (1) CHEMBL1061933 (1)
CHEMBL1908505 (1) CHEMBL1963757 (1)
CHEMBL2219315 (1) CHEMBL2219316 (1)
2 / 4
Q05655 Protein kinase C delta type Delta CHEMBL162 CHEMBL1980995 CHEMBL760364 (1) CHEMBL768252 (1)
CHEMBL766308 (1) CHEMBL766594 (1)
CHEMBL767225 (1) CHEMBL769345 (1)
CHEMBL769348 (1) CHEMBL769354 (1)
CHEMBL766548 (1) CHEMBL772645 (1)
CHEMBL767434 (1) CHEMBL767441 (1)
CHEMBL767445 (1) CHEMBL827792 (1)
CHEMBL830923 (1) CHEMBL864416 (1)
CHEMBL966811 (1) CHEMBL1062865 (1)
CHEMBL1908745 (1) CHEMBL1963703 (1)
CHEMBL2219406 (1) CHEMBL2219407 (1)
0 / 0
Q04759 Protein kinase C theta type Delta CHEMBL162 CHEMBL1980995 CHEMBL760364 (1) CHEMBL767225 (1)
CHEMBL769345 (1) CHEMBL769348 (1)
CHEMBL769354 (1) CHEMBL766548 (1)
CHEMBL772645 (1) CHEMBL767434 (1)
CHEMBL767441 (1) CHEMBL767445 (1)
CHEMBL827792 (1) CHEMBL1051255 (1)
CHEMBL1908748 (1) CHEMBL1963687 (1)
CHEMBL2219115 (1) CHEMBL2219116 (1)
0 / 1
Q15303 Receptor tyrosine-protein kinase erbB-4 TK tyrosine-protein kinase EGFR subfamily CHEMBL162 CHEMBL1980995 CHEMBL973467 (1) CHEMBL1908512 (1)
CHEMBL1963833 (1) CHEMBL2219058 (1)
CHEMBL2219059 (1)
0 / 0
O14757 Serine/threonine-protein kinase Chk1 Chk1 CHEMBL162 CHEMBL364347 CHEMBL1980995 CHEMBL869539 (1) CHEMBL864426 (1)
CHEMBL972528 (1) CHEMBL963403 (1)
CHEMBL1026934 (1) CHEMBL1051597 (1)
CHEMBL1051598 (1) CHEMBL1051602 (1)
CHEMBL1060185 (1) CHEMBL1068401 (1)
CHEMBL1908528 (1) CHEMBL1913732 (1)
CHEMBL1930050 (1) CHEMBL1963782 (1)
CHEMBL2218986 (1) CHEMBL2218987 (1)
0 / 0
O14965 Aurora kinase A Aur CHEMBL162 CHEMBL1980995 CHEMBL859641 (1) CHEMBL972523 (1)
CHEMBL1064037 (1) CHEMBL1062833 (1)
CHEMBL1908616 (1) CHEMBL1913734 (1)
CHEMBL1921566 (1) CHEMBL1963727 (1)
CHEMBL2218948 (1) CHEMBL2218949 (1)
0 / 0
Q7KZI7 Serine/threonine-protein kinase MARK2 CAMK serine/threonine protein kinase MARK subfamily CHEMBL162 CHEMBL1980995 CHEMBL860785 (1) CHEMBL1049903 (1)
CHEMBL1908803 (1) CHEMBL1963834 (1)
CHEMBL2219367 (1) CHEMBL2219368 (1)
0 / 0
Q13882 Protein-tyrosine kinase 6 Src CHEMBL162 CHEMBL861048 (1) CHEMBL1061159 (1)
CHEMBL1908726 (1) CHEMBL2218956 (1)
CHEMBL2218957 (1)
0 / 0
Q8TD19 Serine/threonine-protein kinase Nek9 Nek CHEMBL162 CHEMBL860657 (1) CHEMBL1061081 (1)
CHEMBL1908401 (1)
0 / 0
Q96NX5 Calcium/calmodulin-dependent protein kinase type 1G Camk1 CHEMBL162 CHEMBL860656 (1) CHEMBL1060178 (1)
CHEMBL1908816 (1)
0 / 0
Q99640 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Dual-specificity kinase WEE subfamily CHEMBL162 CHEMBL861047 (1) CHEMBL1061154 (1)
CHEMBL1908454 (1) CHEMBL1948658 (1)
0 / 0
Q9H2G2 STE20-like serine/threonine-protein kinase STE serine/threonine protein kinase SLK subfamily CHEMBL162 CHEMBL860653 (1) CHEMBL1062787 (1)
CHEMBL1908783 (1)
0 / 0
Q9NRP7 Serine/threonine-protein kinase 36 ULK serine/threonine protein kinase subfamily CHEMBL162 CHEMBL860647 (1) CHEMBL1062873 (1)
CHEMBL1908793 (1)
0 / 0
Q9Y2H1 Serine/threonine-protein kinase 38-like AGC serine/threonine protein kinase NDR subfamily CHEMBL162 CHEMBL861050 (1) CHEMBL1060252 (1)
CHEMBL1908789 (1)
0 / 0
Q8IWQ3 Serine/threonine-protein kinase BRSK2 CAMK serine/threonine protein kinase BRSK subfamily CHEMBL162 CHEMBL1061136 (1) CHEMBL1908626 (1)
CHEMBL2218966 (1) CHEMBL2218967 (1)
0 / 0
P27448 MAP/microtubule affinity-regulating kinase 3 CAMK serine/threonine protein kinase MARK subfamily CHEMBL162 CHEMBL1980995 CHEMBL1063802 (1) CHEMBL1908560 (1)
CHEMBL1963756 (1)
0 / 0
Q9UHD2 Serine/threonine-protein kinase TBK1 Ikk CHEMBL162 CHEMBL1980995 CHEMBL1908769 (1) CHEMBL1963698 (1)
CHEMBL2219205 (1) CHEMBL2219206 (1)
1 / 0
Q13546 Receptor-interacting serine/threonine-protein kinase 1 TKL serine/threonine protein kinase RIPK subfamily CHEMBL162 CHEMBL1062869 (1) CHEMBL1908621 (1)
0 / 0
P0C1S8 Wee1-like protein kinase 2 Wee1 CHEMBL162 CHEMBL1908443 (1)
0 / 0
Q16659 Mitogen-activated protein kinase 6 CMGC serine/threonine protein kinase ERK3 subfamily CHEMBL162 CHEMBL1063710 (1) CHEMBL1908584 (1)
0 / 0
Q86YV6 Myosin light chain kinase family member 4 Mlck CHEMBL162 CHEMBL1051352 (1) CHEMBL1908506 (1)
0 / 0
Q8NEV4 Myosin-IIIa STE serine/threonine protein kinase NINAC subfamily CHEMBL162 CHEMBL1061080 (1) CHEMBL1908801 (1)
1 / 1
Q8NI60 Chaperone activity of bc1 complex-like, mitochondrial Enzyme CHEMBL162 CHEMBL1062831 (1) CHEMBL1908813 (1)
1 / 2
O00750 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta Enzyme CHEMBL162 CHEMBL1908574 (1)
0 / 0
Q8TDR2 Serine/threonine-protein kinase 35 Nkf4 CHEMBL162 CHEMBL1908408 (1)
0 / 0
Q92772 Cyclin-dependent kinase-like 2 CMGC serine/threonine protein kinase CDKL subfamily CHEMBL162 CHEMBL1908625 (1)
0 / 0
P21127 Cyclin-dependent kinase 11B Pitslre CHEMBL162 CHEMBL1060184 (1) CHEMBL1908405 (1)
0 / 0
P21709 Ephrin type-A receptor 1 Eph CHEMBL162 CHEMBL1061144 (1) CHEMBL1908705 (1)
CHEMBL2219036 (1) CHEMBL2219037 (1)
0 / 0
P51957 Serine/threonine-protein kinase Nek4 Nek CHEMBL162 CHEMBL1908601 (1)
0 / 0
Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha Kinase CHEMBL162 CHEMBL1061923 (1) CHEMBL1908521 (1)
0 / 0
P27037 Activin receptor type-2A TKL serine/threonine protein kinase STKR type 2 subfamily CHEMBL162 CHEMBL1060234 (1) CHEMBL1908535 (1)
0 / 0
Q9P0L2 Serine/threonine-protein kinase MARK1 CAMK serine/threonine protein kinase MARK subfamily CHEMBL162 CHEMBL1061905 (1) CHEMBL1908810 (1)
CHEMBL2219259 (1) CHEMBL2219260 (1)
0 / 0
P02545 Prelamin-A/C Unclassified protein CHEMBL1537489 CHEMBL1614544 (1)
11 / 10
P57058 Hormonally up-regulated neu tumor-associated kinase Enzyme CHEMBL162 CHEMBL1908781 (1)
0 / 0
O14936 Peripheral plasma membrane protein CASK Enzyme CHEMBL162 CHEMBL1908446 (1)
2 / 2
Q96PF2 Testis-specific serine/threonine-protein kinase 2 CAMK serine/threonine protein kinase TSSK subfamily CHEMBL162 CHEMBL2219309 (1) CHEMBL2219310 (1)
0 / 0
P51956 Serine/threonine-protein kinase Nek3 Nek1 CHEMBL162 CHEMBL1908567 (1) CHEMBL2219303 (1)
CHEMBL2219304 (1)
0 / 0
Q15208 Serine/threonine-protein kinase 38 AGC serine/threonine protein kinase NDR CHEMBL162 CHEMBL1908764 (1)
0 / 0
O43283 Mitogen-activated protein kinase kinase kinase 13 Lzk CHEMBL162 CHEMBL1908662 (1)
0 / 0
P00519 Tyrosine-protein kinase ABL1 Abl CHEMBL162 CHEMBL1980995 CHEMBL846548 (1) CHEMBL827809 (1)
CHEMBL859868 (1) CHEMBL859869 (1)
CHEMBL859870 (1) CHEMBL859871 (1)
CHEMBL859872 (1) CHEMBL859873 (1)
CHEMBL861044 (1) CHEMBL900477 (1)
CHEMBL972521 (1) CHEMBL1060174 (1)
CHEMBL1062829 (1) CHEMBL1062830 (1)
CHEMBL1063789 (1) CHEMBL1061129 (1)
CHEMBL1061130 (1) CHEMBL1051277 (1)
CHEMBL1764256 (1) CHEMBL1817210 (1)
CHEMBL1908675 (1) CHEMBL1908676 (1)
CHEMBL1908677 (1) CHEMBL1908678 (1)
CHEMBL1908679 (1) CHEMBL1908680 (1)
CHEMBL1908681 (1) CHEMBL1908682 (1)
CHEMBL1908683 (1) CHEMBL1908684 (1)
CHEMBL1908685 (1) CHEMBL1908686 (1)
CHEMBL1908687 (1) CHEMBL1908688 (1)
CHEMBL1908689 (1) CHEMBL1921563 (1)
CHEMBL1963785 (1) CHEMBL2218944 (1)
CHEMBL2218945 (1)
1 / 4
P68400 Casein kinase II subunit alpha Ck2 CHEMBL162 CHEMBL1980995 CHEMBL659493 (1) CHEMBL869538 (1)
CHEMBL864420 (1) CHEMBL1060241 (1)
CHEMBL1211279 (1) CHEMBL1908545 (1)
CHEMBL1963735 (1) CHEMBL2218998 (1)
CHEMBL2218999 (1)
0 / 0
P42574 Caspase-3 C14 CHEMBL162 CHEMBL2050974 (1)
0 / 0
Q05513 Protein kinase C zeta type Iota CHEMBL162 CHEMBL1980995 CHEMBL760364 (1) CHEMBL771067 (1)
CHEMBL771068 (1) CHEMBL770272 (1)
CHEMBL767225 (1) CHEMBL769345 (1)
CHEMBL769348 (1) CHEMBL769354 (1)
CHEMBL766548 (1) CHEMBL772645 (1)
CHEMBL767434 (1) CHEMBL767441 (1)
CHEMBL767445 (1) CHEMBL827792 (1)
CHEMBL833044 (1) CHEMBL1832239 (1)
CHEMBL1963694 (1) CHEMBL2219112 (1)
CHEMBL2218942 (1)
0 / 0
Q00534 Cyclin-dependent kinase 6 CMGC serine/threonine protein kinase family CHEMBL162 CHEMBL963383 (1) CHEMBL2218980 (1)
CHEMBL2218981 (1)
1 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim CHEMBL162 CHEMBL1980995 CHEMBL860908 (1) CHEMBL862675 (1)
CHEMBL862676 (1) CHEMBL864489 (2)
CHEMBL973455 (1) CHEMBL957365 (1)
CHEMBL955982 (1) CHEMBL960122 (1)
CHEMBL960123 (1) CHEMBL960124 (1)
CHEMBL1051308 (1) CHEMBL1908575 (1)
CHEMBL1963726 (1) CHEMBL2219135 (1)
CHEMBL2219136 (1)
0 / 0
Q02156 Protein kinase C epsilon type Eta CHEMBL162 CHEMBL760364 (1) CHEMBL769112 (1)
CHEMBL769117 (1) CHEMBL766360 (1)
CHEMBL767225 (1) CHEMBL769345 (1)
CHEMBL769348 (1) CHEMBL769354 (1)
CHEMBL766548 (1) CHEMBL772645 (1)
CHEMBL767434 (1) CHEMBL767441 (1)
CHEMBL767445 (1) CHEMBL827792 (1)
CHEMBL966809 (1) CHEMBL1064035 (1)
CHEMBL1051254 (1) CHEMBL1908711 (1)
CHEMBL2219408 (1) CHEMBL2219409 (1)
0 / 0
P41743 Protein kinase C iota type Iota CHEMBL162 CHEMBL760364 (1) CHEMBL767225 (1)
CHEMBL769345 (1) CHEMBL769348 (1)
CHEMBL769354 (1) CHEMBL766548 (1)
CHEMBL772645 (1) CHEMBL767434 (1)
CHEMBL767441 (1) CHEMBL767445 (1)
CHEMBL827792 (1) CHEMBL966813 (1)
CHEMBL1908580 (1) CHEMBL2219117 (1)
CHEMBL2219118 (1)
0 / 0
Q9UK32 Ribosomal protein S6 kinase alpha-6 Rskb CHEMBL162 CHEMBL1039275 (1) CHEMBL1061926 (1)
CHEMBL1908778 (1) CHEMBL1908779 (1)
CHEMBL2219169 (1) CHEMBL2219170 (1)
0 / 0
Q04912 Macrophage-stimulating protein receptor TK tyrosine-protein kinase MET subfamily CHEMBL162 CHEMBL1980995 CHEMBL1908565 (1) CHEMBL1919770 (1)
CHEMBL1964103 (1) CHEMBL2219157 (1)
CHEMBL2219158 (1)
0 / 0
P08183 Multidrug resistance protein 1 drug CHEMBL162 CHEMBL2077449 (1)
1 / 0
Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta Camk2 CHEMBL162 CHEMBL657561 (1) CHEMBL653818 (1)
CHEMBL767435 (1) CHEMBL860893 (1)
CHEMBL1063792 (1) CHEMBL1908467 (1)
CHEMBL2219014 (1) CHEMBL2219015 (1)
0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 CHEMBL162 CHEMBL665283 (1) CHEMBL664632 (1)
CHEMBL831687 (1) CHEMBL860890 (1)
CHEMBL972527 (1) CHEMBL963375 (1)
CHEMBL963378 (1) CHEMBL1061138 (1)
CHEMBL1908541 (1) CHEMBL1921569 (1)
CHEMBL2216236 (1) CHEMBL2218970 (1)
CHEMBL2218971 (1) CHEMBL2218972 (1)
CHEMBL2218973 (1) CHEMBL2320996 (1)
CHEMBL2320998 (1)
0 / 0
P48729 Casein kinase I isoform alpha Ck1 CHEMBL162 CHEMBL1980995 CHEMBL658117 (1) CHEMBL1211278 (1)
CHEMBL1908543 (1) CHEMBL1963741 (1)
0 / 0
P06241 Tyrosine-protein kinase Fyn Src CHEMBL162 CHEMBL1980995 CHEMBL860888 (1) CHEMBL919495 (1)
CHEMBL919496 (1) CHEMBL919497 (1)
CHEMBL919498 (1) CHEMBL919499 (1)
CHEMBL919500 (1) CHEMBL1061899 (1)
CHEMBL1052172 (1) CHEMBL1908424 (1)
CHEMBL1963817 (1) CHEMBL2219084 (1)
CHEMBL2219085 (1)
0 / 0
P80192 Mitogen-activated protein kinase kinase kinase 9 TKL dual-specificity kinase MLK CHEMBL162 CHEMBL1063716 (1) CHEMBL1908403 (1)
CHEMBL2219273 (1) CHEMBL2219274 (1)
0 / 0
P06493 Cyclin-dependent kinase 1 Cdc2 CHEMBL162 CHEMBL1980995 CHEMBL660793 (1) CHEMBL666084 (1)
CHEMBL831686 (1) CHEMBL864417 (1)
CHEMBL972526 (1) CHEMBL963377 (1)
CHEMBL1051605 (1) CHEMBL1249832 (1)
CHEMBL1250275 (1) CHEMBL1921568 (1)
CHEMBL1963819 (1) CHEMBL2218968 (1)
CHEMBL2218969 (1)
0 / 0
P43403 Tyrosine-protein kinase ZAP-70 Syk CHEMBL162 CHEMBL981177 (1) CHEMBL992588 (1)
CHEMBL1061189 (1) CHEMBL1908441 (1)
CHEMBL1913942 (1) CHEMBL2219333 (1)
CHEMBL2219334 (1)
1 / 2
P16234 Platelet-derived growth factor receptor alpha Pdgfr CHEMBL162 CHEMBL1980995 CHEMBL765716 (1) CHEMBL901555 (1)
CHEMBL973453 (1) CHEMBL1062783 (1)
CHEMBL1817206 (1) CHEMBL1817216 (1)
CHEMBL1908731 (1) CHEMBL1963805 (1)
CHEMBL2219384 (1) CHEMBL2219385 (1)
2 / 1
P19784 Casein kinase II subunit alpha' Ck2 CHEMBL162 CHEMBL659493 (1) CHEMBL869538 (1)
CHEMBL864420 (1) CHEMBL1061141 (1)
CHEMBL1908546 (1) CHEMBL2218998 (1)
CHEMBL2218999 (1) CHEMBL2219000 (1)
CHEMBL2219001 (1)
0 / 0
P23443 Ribosomal protein S6 kinase beta-1 p70 CHEMBL162 CHEMBL1980995 CHEMBL1908603 (1) CHEMBL1963708 (1)
CHEMBL2219349 (1) CHEMBL2219350 (1)
0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 CHEMBL162 CHEMBL1980995 CHEMBL859644 (1) CHEMBL963381 (1)
CHEMBL963382 (1) CHEMBL1037551 (1)
CHEMBL1211212 (1) CHEMBL1211215 (1)
CHEMBL1908667 (1) CHEMBL1963790 (1)
CHEMBL2218976 (1) CHEMBL2218977 (1)
CHEMBL2218978 (1) CHEMBL2218979 (1)
0 / 0
Q9UQB9 Aurora kinase C Aur CHEMBL162 CHEMBL860787 (1) CHEMBL1060236 (1)
CHEMBL1908466 (1) CHEMBL2218952 (1)
CHEMBL2218953 (1)
1 / 1
O00444 Serine/threonine-protein kinase PLK4 PLK serine/threonine protein kinase subfamily CHEMBL162 CHEMBL1980995 CHEMBL860784 (1) CHEMBL1060341 (1)
CHEMBL1908773 (1) CHEMBL1963705 (1)
0 / 0
P49761 Dual specificity protein kinase CLK3 Clk CHEMBL162 CHEMBL860772 (1) CHEMBL1060240 (1)
CHEMBL1908628 (1) CHEMBL2219004 (1)
CHEMBL2219005 (1)
0 / 0
P51813 Cytoplasmic tyrosine-protein kinase BMX Tec CHEMBL162 CHEMBL860771 (1) CHEMBL1061134 (1)
CHEMBL1908539 (1) CHEMBL2218962 (1)
CHEMBL2218963 (1)
0 / 0
Q9HBH9 MAP kinase-interacting serine/threonine-protein kinase 2 CAMK serine/threonine protein kinase MNK subfamily CHEMBL162 CHEMBL860651 (1) CHEMBL1050830 (1)
CHEMBL1908805 (1) CHEMBL2219295 (1)
CHEMBL2219296 (1)
0 / 0
Q9NQU5 Serine/threonine-protein kinase PAK 6 STE serine/threonine protein kinase PAKB subfamily CHEMBL162 CHEMBL860648 (1) CHEMBL1061921 (1)
CHEMBL1908812 (1) CHEMBL2219365 (1)
CHEMBL2219366 (1)
0 / 0
Q9UKE5 TRAF2 and NCK-interacting protein kinase STE serine/threonine protein kinase MSN subfamily CHEMBL162 CHEMBL859485 (1) CHEMBL1062874 (1)
CHEMBL1908790 (1) CHEMBL2319997 (1)
CHEMBL2320000 (1) CHEMBL2317110 (1)
0 / 0
Q16644 MAP kinase-activated protein kinase 3 CAMK serine/threonine protein kinase MAPKAPK CHEMBL162 CHEMBL1980995 CHEMBL1963781 (1) CHEMBL2219257 (1)
CHEMBL2219258 (1)
0 / 0
Q06187 Tyrosine-protein kinase BTK Tec CHEMBL162 CHEMBL1980995 CHEMBL860638 (1) CHEMBL972524 (1)
CHEMBL1060238 (1) CHEMBL1908476 (1)
CHEMBL1963733 (1) CHEMBL2218958 (1)
CHEMBL2218959 (1)
2 / 2
P30291 Wee1-like protein kinase WEE serine/threonine protein kinase subfamily CHEMBL162 CHEMBL1980995 CHEMBL1061935 (1) CHEMBL1908611 (1)
CHEMBL1963774 (1)
0 / 0
Q9H422 Homeodomain-interacting protein kinase 3 CMGC dual-specificity kinase HIPK CHEMBL162 CHEMBL1908720 (1) CHEMBL2219102 (1)
CHEMBL2219103 (1)
0 / 0
Q14680 Maternal embryonic leucine zipper kinase Melk CHEMBL162 CHEMBL1980995 CHEMBL1063803 (1) CHEMBL1908784 (1)
CHEMBL1963804 (1) CHEMBL2219263 (1)
CHEMBL2219264 (1)
0 / 0
Q9P2K8 Eukaryotic translation initiation factor 2-alpha kinase 4 Unique STE serine/threonine protein kinase CHEMBL162 CHEMBL1060248 (1) CHEMBL1908507 (1)
0 / 0
Q9UBE8 Serine/threonine-protein kinase NLK CMGC serine/threonine protein kinase NMO subfamily CHEMBL162 CHEMBL1063809 (1) CHEMBL1908797 (1)
CHEMBL2219355 (1) CHEMBL2219356 (1)
0 / 0
Q12866 Tyrosine-protein kinase Mer TK tyrosine-protein kinase AXL CHEMBL162 CHEMBL1037553 (1) CHEMBL1908464 (1)
CHEMBL2219291 (1) CHEMBL2219292 (1)
1 / 1
Q13470 Non-receptor tyrosine-protein kinase TNK1 Ack CHEMBL162 CHEMBL1062788 (1) CHEMBL1908627 (1)
0 / 0
P14635 G2/mitotic-specific cyclin-B1 Other cytosolic protein CHEMBL162 CHEMBL666084 (1) CHEMBL831686 (1)
CHEMBL1249832 (1) CHEMBL1250275 (1)
CHEMBL1921568 (1) CHEMBL2218968 (1)
CHEMBL2218969 (1)
0 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family CHEMBL162 CHEMBL1211212 (1) CHEMBL1211215 (1)
CHEMBL2218976 (1) CHEMBL2218977 (1)
CHEMBL2218978 (1) CHEMBL2218979 (1)
0 / 0
P11802 Cyclin-dependent kinase 4 CMGC serine/threonine protein kinase family CHEMBL162 CHEMBL666089 (1) CHEMBL665278 (1)
CHEMBL665279 (1) CHEMBL963380 (1)
CHEMBL1908477 (1) CHEMBL1908478 (1)
1 / 3
P24385 G1/S-specific cyclin-D1 Other cytosolic protein CHEMBL162 CHEMBL666089 (1) CHEMBL665278 (1)
CHEMBL665279 (1)
1 / 10
P24864 G1/S-specific cyclin-E1 Other cytosolic protein CHEMBL162 CHEMBL665283 (1) CHEMBL664632 (1)
CHEMBL831687 (1) CHEMBL1921569 (1)
CHEMBL2218972 (1) CHEMBL2218973 (1)
CHEMBL2218974 (1) CHEMBL2218975 (1)
0 / 2
Q9UKI8 Serine/threonine-protein kinase tousled-like 1 TLK serine/threonine protein kinase CHEMBL162 CHEMBL1061931 (1) CHEMBL1908766 (1)
0 / 0
Q13705 Activin receptor type-2B TKL serine/threonine protein kinase STKR type 2 subfamily CHEMBL162 CHEMBL1057608 (1) CHEMBL1908517 (1)
1 / 1
Q9Y5S2 Serine/threonine-protein kinase MRCK beta AGC serine/threonine protein kinase GEK subfamily CHEMBL162 CHEMBL1051290 (1) CHEMBL1908728 (1)
CHEMBL2219277 (1) CHEMBL2219278 (1)
0 / 0
P0C264 Putative uncharacterized serine/threonine-protein kinase SgK110 NKF1 serine/threonine protein kinase subfamily CHEMBL162 CHEMBL1908444 (1)
0 / 0
Q8N4C8 Misshapen-like kinase 1 STE serine/threonine protein kinase MSN subfamily CHEMBL162 CHEMBL973449 (1) CHEMBL1908510 (1)
CHEMBL2219265 (1) CHEMBL2219266 (1)
0 / 0
O00506 Serine/threonine-protein kinase 25 STE serine/threonine protein kinase YSK subfamily CHEMBL162 CHEMBL1051263 (1) CHEMBL1908756 (1)
0 / 0
Q96PY6 Serine/threonine-protein kinase Nek1 Nek CHEMBL162 CHEMBL1062846 (1) CHEMBL1908765 (1)
1 / 1
Q99558 Mitogen-activated protein kinase kinase kinase 14 Unique STE serine/threonine protein kinase CHEMBL162 CHEMBL1212349 (1)
0 / 0
Q9BVS4 Serine/threonine-protein kinase RIO2 Rio2 CHEMBL162 CHEMBL1908808 (1)
0 / 0
Q9C098 Serine/threonine-protein kinase DCLK3 CAMK serine/threonine protein kinase DCAMK1 CHEMBL162 CHEMBL1060188 (1) CHEMBL1908404 (1)
0 / 0
P29376 Leukocyte tyrosine kinase receptor Alk CHEMBL162 CHEMBL1980995 CHEMBL1061078 (1) CHEMBL1908440 (1)
CHEMBL1964115 (1)
0 / 0
Q9H093 NUAK family SNF1-like kinase 2 CAMK serine/threonine protein kinase NUAK subfamily CHEMBL162 CHEMBL1062871 (1) CHEMBL1908836 (1)
0 / 0
Q9H3Y6 Tyrosine-protein kinase Srms TK tyrosine-protein kinase SRM subfamily CHEMBL162 CHEMBL1062872 (1) CHEMBL1908407 (1)
0 / 0
P32298 G protein-coupled receptor kinase 4 AGC serine/threonine protein kinase GRK subfamily CHEMBL162 CHEMBL1908436 (1)
0 / 0
Q9NYY3 Serine/threonine-protein kinase PLK2 Plk2 CHEMBL162 CHEMBL973458 (1) CHEMBL1908760 (1)
CHEMBL2219193 (1) CHEMBL2219194 (1)
0 / 0
Q9P289 Serine/threonine-protein kinase MST4 STE serine/threonine protein kinase YSK subfamily CHEMBL162 CHEMBL1063806 (1) CHEMBL1908800 (1)
0 / 0
P43250 G protein-coupled receptor kinase 6 AGC serine/threonine protein kinase GRK subfamily CHEMBL162 CHEMBL2219090 (1) CHEMBL2219091 (1)
0 / 0
Q96BR1 Serine/threonine-protein kinase Sgk3 AGC serine/threonine protein kinase SGK subfamily CHEMBL162 CHEMBL1908770 (1) CHEMBL2219183 (1)
CHEMBL2219184 (1)
0 / 0
Q9Y2K2 Serine/threonine-protein kinase SIK3 CAMK serine/threonine protein kinase QIK subfamily CHEMBL162 CHEMBL1908471 (1)
0 / 0
O75747 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma Enzyme CHEMBL162 CHEMBL1908655 (1)
0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL162 CHEMBL388978 CHEMBL1980995 CHEMBL677890 (1) CHEMBL677530 (1)
CHEMBL859867 (1) CHEMBL900481 (1)
CHEMBL972533 (1) CHEMBL1060182 (1)
CHEMBL1061068 (1) CHEMBL1060190 (1)
CHEMBL1062839 (1) CHEMBL1063796 (1)
CHEMBL1063797 (1) CHEMBL1061143 (1)
CHEMBL1050839 (1) CHEMBL1051285 (1)
CHEMBL1051286 (1) CHEMBL1211280 (1)
CHEMBL1614386 (1) CHEMBL1614511 (1)
CHEMBL1614189 (1) CHEMBL1614029 (1)
CHEMBL1817205 (1) CHEMBL1817215 (1)
CHEMBL1908693 (1) CHEMBL1908694 (1)
CHEMBL1908695 (1) CHEMBL1908696 (1)
CHEMBL1908697 (1) CHEMBL1908698 (1)
CHEMBL1908699 (1) CHEMBL1908700 (1)
CHEMBL1908701 (1) CHEMBL1908702 (1)
CHEMBL1908703 (1) CHEMBL1908704 (1)
CHEMBL1921573 (1) CHEMBL1963766 (1)
CHEMBL2219034 (1) CHEMBL2219035 (1)
CHEMBL2338950 (1) CHEMBL2352239 (1)
CHEMBL2352240 (1)
1 / 11
O43293 Death-associated protein kinase 3 Dapk CHEMBL162 CHEMBL1980995 CHEMBL860917 (1) CHEMBL1060181 (1)
CHEMBL1060187 (1) CHEMBL1908531 (1)
CHEMBL1963719 (1) CHEMBL2219335 (1)
CHEMBL2219336 (1)
0 / 0
P22694 cAMP-dependent protein kinase catalytic subunit beta Pka CHEMBL162 CHEMBL769033 (1) CHEMBL769034 (1)
CHEMBL772601 (1) CHEMBL772604 (1)
CHEMBL772605 (1) CHEMBL767993 (1)
CHEMBL767996 (1) CHEMBL768001 (1)
CHEMBL869531 (1) CHEMBL864414 (1)
CHEMBL868610 (1) CHEMBL1039274 (1)
CHEMBL1768516 (1) CHEMBL1908579 (1)
0 / 0
Q15746 Myosin light chain kinase, smooth muscle Mlck CHEMBL162 CHEMBL747420 (1) CHEMBL841528 (1)
CHEMBL1050836 (1) CHEMBL1908406 (1)
CHEMBL2219271 (1) CHEMBL2219272 (1)
1 / 1
Q13188 Serine/threonine-protein kinase 3 STE serine/threonine protein kinase MST subfamily CHEMBL162 CHEMBL1980995 CHEMBL973450 (1) CHEMBL1063805 (1)
CHEMBL1908751 (1) CHEMBL1964119 (1)
CHEMBL2219287 (1) CHEMBL2219288 (1)
0 / 0
P31751 RAC-beta serine/threonine-protein kinase Akt CHEMBL162 CHEMBL1980995 CHEMBL869529 (1) CHEMBL862613 (1)
CHEMBL868046 (1) CHEMBL868623 (1)
CHEMBL868624 (1) CHEMBL868630 (1)
CHEMBL1062832 (1) CHEMBL1908536 (1)
CHEMBL1963739 (1) CHEMBL2219394 (1)
CHEMBL2219395 (1)
2 / 2
Q9Y243 RAC-gamma serine/threonine-protein kinase Akt CHEMBL162 CHEMBL1980995 CHEMBL869530 (1) CHEMBL862615 (1)
CHEMBL868609 (1) CHEMBL868623 (1)
CHEMBL868624 (1) CHEMBL868630 (1)
CHEMBL963402 (1) CHEMBL1051280 (1)
CHEMBL1908716 (1) CHEMBL1963699 (1)
CHEMBL2219396 (1) CHEMBL2219397 (1)
1 / 0
O75582 Ribosomal protein S6 kinase alpha-5 CAMK serine/threonine protein kinase MSKB subfamily CHEMBL162 CHEMBL860906 (1) CHEMBL1037545 (1)
CHEMBL1056938 (1) CHEMBL1908433 (1)
CHEMBL1908664 (1) CHEMBL2219279 (1)
CHEMBL2219280 (1)
0 / 0
O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta Other serine/threonine protein kinase CHEMBL162 CHEMBL1980995 CHEMBL827106 (1) CHEMBL963407 (1)
CHEMBL1064036 (1) CHEMBL1764342 (1)
CHEMBL1908533 (1) CHEMBL1964112 (1)
CHEMBL2219213 (1) CHEMBL2219214 (1)
0 / 0
O95977 Sphingosine 1-phosphate receptor 4 EDG receptor CHEMBL1537489 CHEMBL1614498 (1)
0 / 0
Q13464 Rho-associated protein kinase 1 Rock CHEMBL162 CHEMBL1980995 CHEMBL973460 (1) CHEMBL1908712 (1)
CHEMBL1963814 (1) CHEMBL2219151 (1)
CHEMBL2219152 (1)
0 / 0
Q16513 Serine/threonine-protein kinase N2 Pkn CHEMBL162 CHEMBL1980995 CHEMBL1051310 (1) CHEMBL1908747 (1)
CHEMBL1963748 (1) CHEMBL2219129 (1)
CHEMBL2219130 (1)
0 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd CHEMBL162 CHEMBL760364 (1) CHEMBL767225 (1)
CHEMBL769345 (1) CHEMBL769348 (1)
CHEMBL769354 (1) CHEMBL766548 (1)
CHEMBL772645 (1) CHEMBL767434 (1)
CHEMBL767441 (1) CHEMBL767445 (1)
CHEMBL827792 (1) CHEMBL1061155 (1)
CHEMBL1908581 (1) CHEMBL2219119 (1)
CHEMBL2219120 (1)
0 / 0
P23458 Tyrosine-protein kinase JAK1 Jakb CHEMBL162 CHEMBL860904 (1) CHEMBL1057717 (1)
CHEMBL1908555 (1) CHEMBL1908556 (1)
0 / 0
P49674 Casein kinase I isoform epsilon Ck1 CHEMBL162 CHEMBL658117 (1) CHEMBL860902 (1)
CHEMBL1050834 (1) CHEMBL1908544 (1)
0 / 0
P17948 Vascular endothelial growth factor receptor 1 Vegfr CHEMBL162 CHEMBL1980995 CHEMBL972541 (1) CHEMBL1061174 (1)
CHEMBL1817208 (1) CHEMBL1908550 (1)
CHEMBL1963826 (1) CHEMBL2219076 (1)
CHEMBL2219077 (1)
0 / 0
P36507 Dual specificity mitogen-activated protein kinase kinase 2 Ste7 CHEMBL162 CHEMBL1980995 CHEMBL1061079 (1) CHEMBL1286032 (1)
CHEMBL1286033 (1) CHEMBL1908834 (1)
CHEMBL1964106 (1)
1 / 1
P45985 Dual specificity mitogen-activated protein kinase kinase 4 Ste7 CHEMBL162 CHEMBL732811 (1) CHEMBL1062778 (1)
CHEMBL1908599 (1)
0 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL388978 CHEMBL1614458 (1)
0 / 0
P78368 Casein kinase I isoform gamma-2 Ck1 CHEMBL162 CHEMBL658117 (1) CHEMBL860892 (1)
CHEMBL1063704 (1) CHEMBL1908530 (1)
CHEMBL2218992 (1) CHEMBL2218993 (1)
0 / 0
P21453 Sphingosine 1-phosphate receptor 1 EDG receptor CHEMBL1537489 CHEMBL1614525 (1)
0 / 0
Q16584 Mitogen-activated protein kinase kinase kinase 11 TKL dual-specificity kinase MLK CHEMBL162 CHEMBL1050827 (1) CHEMBL1908563 (1)
0 / 0
Q02779 Mitogen-activated protein kinase kinase kinase 10 TKL dual-specificity kinase MLK CHEMBL162 CHEMBL1980995 CHEMBL1061177 (1) CHEMBL1908564 (1)
CHEMBL1964110 (1)
0 / 0
Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha Camk2 CHEMBL162 CHEMBL1980995 CHEMBL657561 (1) CHEMBL653818 (1)
CHEMBL767435 (1) CHEMBL860798 (1)
CHEMBL868614 (1) CHEMBL1062835 (1)
CHEMBL1908427 (1) CHEMBL1964111 (1)
0 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr CHEMBL162 CHEMBL1980995 CHEMBL860797 (1) CHEMBL901553 (1)
CHEMBL972542 (1) CHEMBL1061073 (1)
CHEMBL1063729 (1) CHEMBL1060194 (1)
CHEMBL1050826 (1) CHEMBL1061898 (1)
CHEMBL1908631 (1) CHEMBL1908632 (1)
CHEMBL1908633 (1) CHEMBL1908634 (1)
CHEMBL1908635 (1) CHEMBL1908636 (1)
CHEMBL1908637 (1) CHEMBL1921578 (1)
CHEMBL1941739 (1) CHEMBL1963779 (1)
CHEMBL2214348 (1) CHEMBL2219078 (1)
CHEMBL2219079 (1)
1 / 1
P29597 Non-receptor tyrosine-protein kinase TYK2 Jakb CHEMBL162 CHEMBL1061188 (1) CHEMBL1908609 (1)
CHEMBL1908610 (1)
1 / 1
P07947 Tyrosine-protein kinase Yes Src CHEMBL162 CHEMBL859642 (1) CHEMBL1051262 (1)
CHEMBL1908715 (1) CHEMBL2219331 (1)
CHEMBL2219332 (1)
0 / 0
P51617 Interleukin-1 receptor-associated kinase 1 Irak CHEMBL162 CHEMBL1908534 (1) CHEMBL2219219 (1)
CHEMBL2219220 (1)
0 / 0
Q9NWZ3 Interleukin-1 receptor-associated kinase 4 Irak CHEMBL162 CHEMBL1980995 CHEMBL973443 (1) CHEMBL1908795 (1)
CHEMBL1963808 (1) CHEMBL2219221 (1)
CHEMBL2219222 (1)
2 / 1
Q9NYL2 Mitogen-activated protein kinase kinase kinase MLT TKL dual-specificity kinase MLK CHEMBL162 CHEMBL1051317 (1) CHEMBL1908452 (1)
0 / 0
O43353 Receptor-interacting serine/threonine-protein kinase 2 Ripk CHEMBL162 CHEMBL860788 (1) CHEMBL1051312 (1)
CHEMBL1908622 (1) CHEMBL2219149 (1)
CHEMBL2219150 (1)
0 / 0
O94768 Serine/threonine-protein kinase 17B Dapk CHEMBL162 CHEMBL860782 (1) CHEMBL1060189 (1)
CHEMBL1908639 (1)
0 / 0
P29320 Ephrin type-A receptor 3 Eph CHEMBL162 CHEMBL860778 (1) CHEMBL972534 (1)
CHEMBL1061145 (1) CHEMBL1908706 (1)
CHEMBL2219040 (1) CHEMBL2219041 (1)
1 / 0
P54764 Ephrin type-A receptor 4 Eph CHEMBL162 CHEMBL860664 (1) CHEMBL1061895 (1)
CHEMBL1908649 (1) CHEMBL2219042 (1)
CHEMBL2219043 (1)
0 / 0
Q00536 Cyclin-dependent kinase 16 CMGC serine/threonine protein kinase TAIRE subfamily CHEMBL162 CHEMBL860663 (1) CHEMBL1051303 (1)
CHEMBL1908730 (1)
0 / 0
Q8N5S9 Calcium/calmodulin-dependent protein kinase kinase 1 META serine/threonine protein kinase subfamily CHEMBL162 CHEMBL860658 (1) CHEMBL1062836 (1)
CHEMBL1908840 (1)
0 / 0
Q9P286 Serine/threonine-protein kinase PAK 7 STE serine/threonine protein kinase PAKB subfamily CHEMBL162 CHEMBL859488 (1) CHEMBL1051348 (1)
CHEMBL1908814 (1) CHEMBL2219363 (1)
CHEMBL2219364 (1)
0 / 0
Q16620 BDNF/NT-3 growth factors receptor Trk CHEMBL162 CHEMBL1980995 CHEMBL1062875 (1) CHEMBL1908729 (1)
CHEMBL1919773 (1) CHEMBL1963832 (1)
CHEMBL2219317 (1) CHEMBL2219318 (1)
1 / 1
P42680 Tyrosine-protein kinase Tec Tec CHEMBL162 CHEMBL901557 (1) CHEMBL1061929 (1)
CHEMBL1908605 (1) CHEMBL2219311 (1)
CHEMBL2219312 (1)
0 / 0
P42681 Tyrosine-protein kinase TXK Tec CHEMBL162 CHEMBL1061187 (1) CHEMBL1908608 (1)
CHEMBL2219319 (1) CHEMBL2219320 (1)
0 / 0
Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 Enzyme CHEMBL162 CHEMBL908189 (1)
0 / 0
Q96SB4 SRSF protein kinase 1 Srpk CHEMBL162 CHEMBL1051313 (1) CHEMBL1908600 (1)
CHEMBL2219187 (1) CHEMBL2219188 (1)
0 / 0
Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 CMGC dual-specificity kinase DYRK2 CHEMBL162 CHEMBL1908615 (1) CHEMBL2219032 (1)
CHEMBL2219033 (1)
0 / 0
P07332 Tyrosine-protein kinase Fes/Fps Fer CHEMBL162 CHEMBL1061072 (1) CHEMBL1908549 (1)
CHEMBL2219072 (1) CHEMBL2219073 (1)
0 / 0
O96013 Serine/threonine-protein kinase PAK 4 STE serine/threonine protein kinase PAKB subfamily CHEMBL162 CHEMBL1980995 CHEMBL860639 (1) CHEMBL1051307 (1)
CHEMBL1908508 (1) CHEMBL1963736 (1)
CHEMBL2219361 (1) CHEMBL2219362 (1)
0 / 0
P09769 Tyrosine-protein kinase Fgr Src CHEMBL162 CHEMBL860637 (1) CHEMBL1050840 (1)
CHEMBL1908708 (1) CHEMBL2219074 (1)
CHEMBL2219075 (1)
0 / 0
P54760 Ephrin type-B receptor 4 Eph CHEMBL162 CHEMBL860636 (1) CHEMBL900483 (1)
CHEMBL972535 (1) CHEMBL1060192 (1)
CHEMBL1908653 (1) CHEMBL2219056 (1)
CHEMBL2219057 (1)
0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL388978 CHEMBL1738606 (1)
0 / 0
Q09013 Myotonin-protein kinase AGC serine/threonine protein kinase GEK subfamily CHEMBL162 CHEMBL1063706 (1) CHEMBL1908647 (1)
CHEMBL2219028 (1) CHEMBL2219029 (1)
1 / 1
Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B CMGC dual-specificity kinase DYRK1 CHEMBL162 CHEMBL1980995 CHEMBL1060243 (1) CHEMBL1908661 (1)
CHEMBL1963799 (1)
0 / 0
Q6DT37 Serine/threonine-protein kinase MRCK gamma AGC serine/threonine protein kinase GEK subfamily CHEMBL162 CHEMBL1060242 (1) CHEMBL1908804 (1)
0 / 0
Q16832 Discoidin domain-containing receptor 2 Ddr CHEMBL162 CHEMBL1060180 (1) CHEMBL1908474 (1)
CHEMBL2219026 (1) CHEMBL2219027 (1)
1 / 1
Q8IYT8 Serine/threonine-protein kinase ULK2 ULK serine/threonine protein kinase CHEMBL162 CHEMBL1908782 (1) CHEMBL2219321 (1)
CHEMBL2219322 (1)
0 / 0
O14578 Citron Rho-interacting kinase Crik CHEMBL162 CHEMBL1062838 (1) CHEMBL1908762 (1)
0 / 0
Q9BWU1 Cyclin-dependent kinase 19 Cdk8 CHEMBL162 CHEMBL1062837 (1) CHEMBL1908791 (1)
0 / 0
Q9BYT3 Serine/threonine-protein kinase 33 Unique CAMK serine/threonine protein kinase CHEMBL162 CHEMBL1061983 (1) CHEMBL1908835 (1)
CHEMBL2219191 (1) CHEMBL2219192 (1)
0 / 0
P57059 Serine/threonine-protein kinase SIK1 CAMK serine/threonine protein kinase QIK subfamily CHEMBL162 CHEMBL1050832 (1) CHEMBL1908430 (1)
CHEMBL2219185 (1) CHEMBL2219186 (1)
0 / 0
O95819 Mitogen-activated protein kinase kinase kinase kinase 4 STE serine/threonine protein kinase MSN subfamily CHEMBL162 CHEMBL1980995 CHEMBL1037548 (1) CHEMBL1908453 (1)
CHEMBL1964101 (1)
0 / 0
P78362 SRSF protein kinase 2 Srpk CHEMBL162 CHEMBL1061928 (1) CHEMBL1908465 (1)
CHEMBL2219189 (1) CHEMBL2219190 (1)
0 / 0
Q9HBY8 Serine/threonine-protein kinase Sgk2 AGC serine/threonine protein kinase SGK subfamily CHEMBL162 CHEMBL1980995 CHEMBL1963793 (1) CHEMBL2219181 (1)
CHEMBL2219182 (1)
0 / 0
Q9NRM7 Serine/threonine-protein kinase LATS2 AGC serine/threonine protein kinase NDR CHEMBL162 CHEMBL1060249 (1) CHEMBL1908780 (1)
0 / 0
O75496 Geminin Unclassified protein CHEMBL1537489 CHEMBL2114843 (1) CHEMBL2114780 (1)
0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein CHEMBL1537489 CHEMBL1613838 (1)
0 / 0
Q9BX84 Transient receptor potential cation channel subfamily M member 6 Enzyme CHEMBL162 CHEMBL1908807 (1)
1 / 1
Q86Y07 Serine/threonine-protein kinase VRK2 Enzyme CHEMBL162 CHEMBL1908755 (1) CHEMBL2219325 (1)
CHEMBL2219326 (1)
0 / 0
Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Enzyme CHEMBL162 CHEMBL1908831 (1)
0 / 0
Q9Y3S1 Serine/threonine-protein kinase WNK2 WNK serine/threonine protein kinase subfamily CHEMBL162 CHEMBL2219327 (1) CHEMBL2219328 (1)
0 / 0
Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 Hri CHEMBL162 CHEMBL1908777 (1)
0 / 0
Q9Y2T6 G-protein coupled receptor 55 Lysophosphatidylinositol receptor CHEMBL1537489 CHEMBL1614165 (1)
0 / 0
O76039 Cyclin-dependent kinase-like 5 CMGC serine/threonine protein kinase CDKL subfamily CHEMBL162 CHEMBL1908602 (1)
1 / 2
P49841 Glycogen synthase kinase-3 beta Gsk CHEMBL162 CHEMBL1980995 CHEMBL686321 (1) CHEMBL686323 (1)
CHEMBL685260 (1) CHEMBL833508 (1)
CHEMBL832375 (1) CHEMBL868620 (1)
CHEMBL972544 (1) CHEMBL1034478 (1)
CHEMBL1064034 (1) CHEMBL1061419 (1)
CHEMBL1061074 (1) CHEMBL1102102 (1)
CHEMBL1113076 (1) CHEMBL1113077 (1)
CHEMBL1211211 (1) CHEMBL1211213 (1)
CHEMBL1908553 (1) CHEMBL1921580 (1)
CHEMBL1941740 (1) CHEMBL1963830 (1)
CHEMBL2219096 (1) CHEMBL2219097 (1)
0 / 0
Q15418 Ribosomal protein S6 kinase alpha-1 Rskb CHEMBL162 CHEMBL973461 (1) CHEMBL1051351 (1)
CHEMBL1062785 (1) CHEMBL1908597 (1)
CHEMBL1908598 (1) CHEMBL1913892 (1)
CHEMBL2219163 (1) CHEMBL2219164 (1)
0 / 0
O15264 Mitogen-activated protein kinase 13 p38 CHEMBL162 CHEMBL1980995 CHEMBL732633 (1) CHEMBL1908589 (1)
CHEMBL1963761 (1) CHEMBL2219177 (1)
CHEMBL2219178 (1)
0 / 0
P42684 Abelson tyrosine-protein kinase 2 Abl CHEMBL162 CHEMBL846548 (1) CHEMBL860899 (1)
CHEMBL1061131 (1) CHEMBL1764253 (1)
CHEMBL1908690 (1) CHEMBL2218946 (1)
CHEMBL2218947 (1)
0 / 0
Q05397 Focal adhesion kinase 1 Fak CHEMBL162 CHEMBL1980995 CHEMBL860898 (1) CHEMBL900484 (1)
CHEMBL1061093 (1) CHEMBL1838972 (1)
CHEMBL1908426 (1) CHEMBL1921575 (1)
CHEMBL1963801 (1) CHEMBL2219060 (1)
CHEMBL2219061 (1)
0 / 0
P53779 Mitogen-activated protein kinase 10 Jnk CHEMBL162 CHEMBL1980995 CHEMBL860894 (1) CHEMBL1063713 (1)
CHEMBL1908588 (1) CHEMBL1964109 (1)
CHEMBL2219235 (1) CHEMBL2219236 (1)
0 / 1
P29323 Ephrin type-B receptor 2 Eph CHEMBL162 CHEMBL1063709 (1) CHEMBL1908802 (1)
CHEMBL2219052 (1) CHEMBL2219053 (1)
2 / 0
O75914 Serine/threonine-protein kinase PAK 3 STE serine/threonine protein kinase PAKA subfamily CHEMBL162 CHEMBL860802 (1) CHEMBL1062779 (1)
CHEMBL1908570 (1) CHEMBL2219359 (1)
CHEMBL2219360 (1)
1 / 1
Q9H1R3 Myosin light chain kinase 2, skeletal/cardiac muscle Mlck CHEMBL162 CHEMBL860800 (1) CHEMBL1061160 (1)
CHEMBL1908402 (1)
1 / 0
P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform Phk CHEMBL162 CHEMBL765147 (1) CHEMBL860795 (1)
CHEMBL973454 (1) CHEMBL1037549 (1)
CHEMBL1908494 (1) CHEMBL2219133 (1)
CHEMBL2219134 (1)
1 / 1
Q00526 Cyclin-dependent kinase 3 Cdc2 CHEMBL162 CHEMBL963379 (1) CHEMBL1043736 (1)
CHEMBL1908525 (1) CHEMBL2218974 (1)
CHEMBL2218975 (1)
0 / 0
Q02763 Angiopoietin-1 receptor Tie CHEMBL162 CHEMBL860794 (1) CHEMBL901558 (1)
CHEMBL973465 (1) CHEMBL1051315 (1)
CHEMBL1908496 (1) CHEMBL2219313 (1)
CHEMBL2219314 (1)
1 / 1
Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Other serine/threonine protein kinase CHEMBL162 CHEMBL1980995 CHEMBL1050835 (1) CHEMBL1908771 (1)
CHEMBL1964108 (1)
0 / 0
P29317 Ephrin type-A receptor 2 Eph CHEMBL162 CHEMBL1980995 CHEMBL860779 (1) CHEMBL900482 (1)
CHEMBL1051287 (1) CHEMBL1908648 (1)
CHEMBL1963791 (1) CHEMBL2219038 (1)
CHEMBL2219039 (1)
1 / 1
P51955 Serine/threonine-protein kinase Nek2 Nek CHEMBL162 CHEMBL1980995 CHEMBL860668 (1) CHEMBL1063807 (1)
CHEMBL1908566 (1) CHEMBL1963823 (1)
CHEMBL2219301 (1) CHEMBL2219302 (1)
0 / 0
Q15375 Ephrin type-A receptor 7 Eph CHEMBL162 CHEMBL860660 (1) CHEMBL1063707 (1)
CHEMBL1908650 (1) CHEMBL2219046 (1)
CHEMBL2219047 (1)
0 / 0
Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 META serine/threonine protein kinase subfamily CHEMBL162 CHEMBL1980995 CHEMBL860655 (1) CHEMBL1063793 (1)
CHEMBL1908757 (1) CHEMBL1963755 (1)
0 / 0
Q99683 Mitogen-activated protein kinase kinase kinase 5 Ste11 CHEMBL162 CHEMBL860654 (1) CHEMBL965354 (1)
CHEMBL965356 (1) CHEMBL965357 (1)
CHEMBL1060199 (1) CHEMBL1908725 (1)
CHEMBL2219383 (1) CHEMBL2218943 (1)
0 / 0
Q9NSY1 BMP-2-inducible protein kinase NAK serine/threonine protein kinase subfamily CHEMBL162 CHEMBL860646 (1) CHEMBL1063698 (1)
CHEMBL1908806 (1)
0 / 0
Q9UF33 Ephrin type-A receptor 6 Eph CHEMBL162 CHEMBL859486 (1) CHEMBL1060244 (1)
CHEMBL1908445 (1)
0 / 0
Q9H4B4 Serine/threonine-protein kinase PLK3 PLK serine/threonine protein kinase subfamily CHEMBL162 CHEMBL1980995 CHEMBL1061092 (1) CHEMBL1908630 (1)
CHEMBL1963697 (1) CHEMBL2219143 (1)
CHEMBL2219144 (1)
0 / 0
P54753 Ephrin type-B receptor 3 Eph CHEMBL162 CHEMBL1061070 (1) CHEMBL1908652 (1)
CHEMBL2219054 (1) CHEMBL2219055 (1)
0 / 0
Q9UM73 ALK tyrosine kinase receptor TKL serine/threonine protein kinase STKR type 1 subfamily CHEMBL162 CHEMBL1980995 CHEMBL1050837 (1) CHEMBL1908641 (1)
CHEMBL1913894 (1) CHEMBL1921565 (1)
CHEMBL1963704 (1) CHEMBL2219373 (1)
CHEMBL2219374 (1)
1 / 1
Q9BUB5 MAP kinase-interacting serine/threonine-protein kinase 1 CAMK serine/threonine protein kinase MNK subfamily CHEMBL162 CHEMBL1063804 (1) CHEMBL1908520 (1)
0 / 0
P15056 Serine/threonine-protein kinase B-raf Raf CHEMBL162 CHEMBL1051281 (1) CHEMBL1051282 (1)
CHEMBL1908643 (1) CHEMBL1908644 (1)
6 / 3
P35590 Tyrosine-protein kinase receptor Tie-1 Tie CHEMBL162 CHEMBL1061930 (1) CHEMBL1908714 (1)
0 / 0
Q13164 Mitogen-activated protein kinase 7 CMGC serine/threonine protein kinase ERK5 subfamily CHEMBL162 CHEMBL1063799 (1) CHEMBL1908585 (1)
0 / 0
Q9UQ88 Cyclin-dependent kinase 11A Pitslre CHEMBL162 CHEMBL1063794 (1) CHEMBL1908830 (1)
0 / 0
Q13873 Bone morphogenetic protein receptor type-2 TKL serine/threonine protein kinase STKR type 2 subfamily CHEMBL162 CHEMBL1061133 (1) CHEMBL1908523 (1)
2 / 1
Q6P3R8 Serine/threonine-protein kinase Nek5 Nek CHEMBL162 CHEMBL1062847 (1) CHEMBL1908439 (1)
0 / 0
O14730 Serine/threonine-protein kinase RIO3 Rio3 CHEMBL162 CHEMBL1061924 (1) CHEMBL1908623 (1)
0 / 0
O15146 Muscle, skeletal receptor tyrosine-protein kinase Musk CHEMBL162 CHEMBL1051339 (1) CHEMBL1908719 (1)
CHEMBL2219297 (1) CHEMBL2219298 (1)
1 / 1
Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 STE serine/threonine protein kinase KHS subfamily CHEMBL162 CHEMBL1061176 (1) CHEMBL1908513 (1)
0 / 0
O60285 NUAK family SNF1-like kinase 1 CAMK serine/threonine protein kinase NUAK subfamily CHEMBL162 CHEMBL1060177 (1) CHEMBL1908785 (1)
CHEMBL2219381 (1) CHEMBL2219382 (1)
0 / 0
P53671 LIM domain kinase 2 Limk CHEMBL162 CHEMBL1063714 (1) CHEMBL1908718 (1)
0 / 0
P57078 Receptor-interacting serine/threonine-protein kinase 4 TKL serine/threonine protein kinase RIPK subfamily CHEMBL162 CHEMBL1908460 (1)
1 / 0
P78356 Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Kinase CHEMBL162 CHEMBL1062784 (1) CHEMBL1908612 (1)
0 / 0
Q00532 Cyclin-dependent kinase-like 1 CMGC serine/threonine protein kinase CDKL subfamily CHEMBL162 CHEMBL1908638 (1)
0 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL1537489 CHEMBL388978 CHEMBL1614257 (2) CHEMBL1614410 (1)
1 / 3
Q14004 Cyclin-dependent kinase 13 Enzyme CHEMBL162 CHEMBL1908458 (1)
0 / 0
Q13523 Serine/threonine-protein kinase PRP4 homolog Enzyme CHEMBL162 CHEMBL1908447 (1)
0 / 0
Q9NRH2 SNF-related serine/threonine-protein kinase Enzyme CHEMBL162 CHEMBL1908449 (1)
0 / 0
Q96RG2 PAS domain-containing serine/threonine-protein kinase Pask CHEMBL162 CHEMBL2219369 (1) CHEMBL2219370 (1)
0 / 0
P34947 G protein-coupled receptor kinase 5 AGC serine/threonine protein kinase GRK subfamily CHEMBL162 CHEMBL1980995 CHEMBL1963789 (1) CHEMBL2219088 (1)
CHEMBL2219089 (1)
0 / 0
P20794 Serine/threonine-protein kinase MAK CMGC serine/threonine protein kinase MAK subfamily CHEMBL162 CHEMBL1908722 (1)
1 / 0
P06213 Insulin receptor TK tyrosine-protein kinase INSR subfamily CHEMBL162 CHEMBL1980995 CHEMBL699132 (1) CHEMBL859866 (1)
CHEMBL972546 (1) CHEMBL1060195 (1)
CHEMBL1908481 (1) CHEMBL1963759 (1)
CHEMBL2219215 (1) CHEMBL2219216 (1)
CHEMBL2219217 (1) CHEMBL2219218 (1)
5 / 4
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily CHEMBL162 CHEMBL1980995 CHEMBL860920 (1) CHEMBL1061896 (1)
CHEMBL1908501 (1) CHEMBL1963780 (1)
5 / 10
P09619 Platelet-derived growth factor receptor beta Pdgfr CHEMBL162 CHEMBL1980995 CHEMBL765716 (1) CHEMBL860919 (1)
CHEMBL1051304 (1) CHEMBL1817207 (1)
CHEMBL1817443 (1) CHEMBL1908572 (1)
CHEMBL1963778 (1) CHEMBL2219386 (1)
CHEMBL2219387 (1)
5 / 1
P52564 Dual specificity mitogen-activated protein kinase kinase 6 Ste7 CHEMBL162 CHEMBL734025 (1) CHEMBL1051289 (1)
CHEMBL1908592 (1) CHEMBL2219267 (1)
CHEMBL2219268 (1)
0 / 0
P48730 Casein kinase I isoform delta Ck1 CHEMBL162 CHEMBL1980995 CHEMBL658117 (1) CHEMBL1050829 (1)
CHEMBL1908413 (1) CHEMBL1963783 (1)
CHEMBL2218996 (1) CHEMBL2218997 (1)
1 / 0
P12931 Proto-oncogene tyrosine-protein kinase Src Src CHEMBL162 CHEMBL1980995 CHEMBL806345 (1) CHEMBL805366 (1)
CHEMBL805368 (1) CHEMBL808764 (1)
CHEMBL843187 (1) CHEMBL861049 (1)
CHEMBL869543 (1) CHEMBL868837 (1)
CHEMBL901561 (1) CHEMBL972531 (1)
CHEMBL1061927 (1) CHEMBL1220465 (1)
CHEMBL1220466 (1) CHEMBL1646090 (1)
CHEMBL1686335 (1) CHEMBL1816340 (1)
CHEMBL1908713 (1) CHEMBL1913896 (1)
CHEMBL1921572 (1) CHEMBL1936377 (1)
CHEMBL1963768 (1) CHEMBL2210030 (1)
CHEMBL2219341 (1) CHEMBL2219342 (1)
0 / 0
P46734 Dual specificity mitogen-activated protein kinase kinase 3 Ste7 CHEMBL162 CHEMBL1060250 (1) CHEMBL1908591 (1)
0 / 0
O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha Other serine/threonine protein kinase CHEMBL162 CHEMBL1980995 CHEMBL963406 (1) CHEMBL1764343 (1)
CHEMBL1908529 (1) CHEMBL1963776 (1)
CHEMBL2219211 (1) CHEMBL2219212 (1)
1 / 1
Q96GD4 Aurora kinase B Aur CHEMBL162 CHEMBL1980995 CHEMBL1062834 (1) CHEMBL1908469 (1)
CHEMBL1963807 (1) CHEMBL2218950 (1)
CHEMBL2218951 (1)
0 / 0
O75676 Ribosomal protein S6 kinase alpha-4 CAMK serine/threonine protein kinase MSKB subfamily CHEMBL162 CHEMBL1051259 (1) CHEMBL1061185 (1)
CHEMBL1908503 (1) CHEMBL1908624 (1)
CHEMBL2219281 (1) CHEMBL2219282 (1)
0 / 0
P05129 Protein kinase C gamma type Alpha CHEMBL162 CHEMBL1980995 CHEMBL760364 (1) CHEMBL767413 (1)
CHEMBL767415 (1) CHEMBL766915 (1)
CHEMBL767225 (1) CHEMBL769345 (1)
CHEMBL769348 (1) CHEMBL769354 (1)
CHEMBL766548 (1) CHEMBL772645 (1)
CHEMBL767434 (1) CHEMBL767441 (1)
CHEMBL767445 (1) CHEMBL827792 (1)
CHEMBL827980 (1) CHEMBL864415 (1)
CHEMBL966812 (1) CHEMBL1963767 (1)
CHEMBL2219404 (1) CHEMBL2219405 (1)
1 / 1
O60674 Tyrosine-protein kinase JAK2 Jakb CHEMBL162 CHEMBL1537489 CHEMBL1980995 CHEMBL860903 (1) CHEMBL973444 (1)
CHEMBL1063801 (1) CHEMBL1738019 (1)
CHEMBL1738020 (1) CHEMBL1738021 (1)
CHEMBL1908670 (1) CHEMBL1963693 (1)
CHEMBL2219227 (1) CHEMBL2219228 (1)
5 / 2
P35968 Vascular endothelial growth factor receptor 2 Vegfr CHEMBL162 CHEMBL1980995 CHEMBL820699 (1) CHEMBL820211 (1)
CHEMBL829417 (1) CHEMBL860900 (1)
CHEMBL869540 (1) CHEMBL864427 (1)
CHEMBL901560 (1) CHEMBL973446 (1)
CHEMBL1051261 (1) CHEMBL1070927 (1)
CHEMBL1817209 (1) CHEMBL1817444 (1)
CHEMBL1816341 (1) CHEMBL1821203 (1)
CHEMBL1821204 (1) CHEMBL1821205 (1)
CHEMBL1821206 (1) CHEMBL1821207 (1)
CHEMBL1821211 (1) CHEMBL1821212 (1)
CHEMBL1821213 (1) CHEMBL1821214 (1)
CHEMBL1821215 (1) CHEMBL1821216 (1)
CHEMBL1908557 (1) CHEMBL1919761 (1)
CHEMBL1963788 (1) CHEMBL2168092 (1)
CHEMBL2219237 (1) CHEMBL2219238 (1)
CHEMBL2338949 (1)
1 / 0
P49137 MAP kinase-activated protein kinase 2 CAMK serine/threonine protein kinase MAPKAPK CHEMBL162 CHEMBL1980995 CHEMBL864421 (1) CHEMBL1061090 (1)
CHEMBL1071870 (1) CHEMBL1071871 (1)
CHEMBL1071872 (1) CHEMBL1071873 (1)
CHEMBL1100030 (1) CHEMBL1211284 (1)
CHEMBL1908400 (1) CHEMBL1963729 (1)
CHEMBL2167126 (1) CHEMBL2219255 (1)
CHEMBL2219256 (1)
0 / 0
Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 Ampk CHEMBL162 CHEMBL1980995 CHEMBL860896 (1) CHEMBL1060175 (1)
CHEMBL1908470 (1) CHEMBL1963701 (1)
CHEMBL2219377 (1) CHEMBL2219378 (1)
CHEMBL2219379 (1) CHEMBL2219380 (1)
0 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily CHEMBL162 CHEMBL1980995 CHEMBL868612 (1) CHEMBL901552 (1)
CHEMBL972530 (1) CHEMBL1063731 (1)
CHEMBL1908491 (1) CHEMBL1908492 (1)
CHEMBL1908493 (1) CHEMBL1913895 (1)
CHEMBL1921571 (1) CHEMBL1963775 (1)
CHEMBL2219293 (1) CHEMBL2219294 (1)
CHEMBL2338948 (1)
2 / 3
P50750 Cyclin-dependent kinase 9 Cdk9 CHEMBL162 CHEMBL1980995 CHEMBL963384 (1) CHEMBL1063701 (1)
CHEMBL1908527 (1) CHEMBL1963831 (1)
CHEMBL2218984 (1) CHEMBL2218985 (1)
CHEMBL2320997 (1) CHEMBL2320999 (1)
0 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL162 CHEMBL1537489 CHEMBL1980995 CHEMBL680866 (1) CHEMBL729502 (1)
CHEMBL732070 (1) CHEMBL869532 (1)
CHEMBL864418 (1) CHEMBL972537 (1)
CHEMBL1063798 (1) CHEMBL1614521 (1)
CHEMBL1908410 (1) CHEMBL1921574 (1)
CHEMBL1963794 (1) CHEMBL2219253 (1)
CHEMBL2219254 (1) CHEMBL2343186 (1)
0 / 0
P35916 Vascular endothelial growth factor receptor 3 Vegfr CHEMBL162 CHEMBL1980995 CHEMBL860889 (1) CHEMBL869541 (1)
CHEMBL864428 (1) CHEMBL972543 (1)
CHEMBL1060246 (1) CHEMBL1908551 (1)
CHEMBL1963812 (1) CHEMBL2219080 (1)
CHEMBL2219081 (1)
2 / 1
P42679 Megakaryocyte-associated tyrosine-protein kinase Csk CHEMBL162 CHEMBL1908561 (1)
0 / 0
P22455 Fibroblast growth factor receptor 4 Fgfr CHEMBL162 CHEMBL676887 (1) CHEMBL1063800 (1)
CHEMBL1908827 (1) CHEMBL2219068 (1)
CHEMBL2219069 (1)
0 / 0
P22607 Fibroblast growth factor receptor 3 Fgfr CHEMBL162 CHEMBL1980995 CHEMBL676887 (1) CHEMBL860801 (1)
CHEMBL972540 (1) CHEMBL1063711 (1)
CHEMBL1062841 (1) CHEMBL1908479 (1)
CHEMBL1908480 (1) CHEMBL1921577 (1)
CHEMBL1963828 (1) CHEMBL2219066 (1)
CHEMBL2219067 (1)
14 / 6
Q9UBF8 Phosphatidylinositol 4-kinase beta Enzyme CHEMBL162 CHEMBL1908577 (1)
0 / 0
P45983 Mitogen-activated protein kinase 8 Jnk CHEMBL162 CHEMBL1980995 CHEMBL860799 (1) CHEMBL1061076 (1)
CHEMBL1211283 (1) CHEMBL1908586 (1)
CHEMBL1919760 (1) CHEMBL1963725 (1)
CHEMBL2219231 (1) CHEMBL2219232 (1)
CHEMBL2343188 (1)
0 / 0
P50613 Cyclin-dependent kinase 7 Cdk7 CHEMBL162 CHEMBL1980995 CHEMBL1063700 (1) CHEMBL1908542 (1)
CHEMBL1963825 (1) CHEMBL2218982 (1)
CHEMBL2218983 (1)
0 / 0
O14976 Cyclin-G-associated kinase NAK serine/threonine protein kinase subfamily CHEMBL162 CHEMBL860789 (1) CHEMBL1062777 (1)
CHEMBL1908709 (1)
0 / 0
O94804 Serine/threonine-protein kinase 10 STE serine/threonine protein kinase SLK subfamily CHEMBL162 CHEMBL860781 (1) CHEMBL1051338 (1)
CHEMBL1908727 (1) CHEMBL2219243 (1)
CHEMBL2219244 (1)
1 / 0
P53667 LIM domain kinase 1 Limk CHEMBL162 CHEMBL1980995 CHEMBL860667 (1) CHEMBL1061902 (1)
CHEMBL1908558 (1) CHEMBL1963749 (1)
CHEMBL2219239 (1) CHEMBL2219240 (1)
0 / 0
Q13153 Serine/threonine-protein kinase PAK 1 STE serine/threonine protein kinase PAKA subfamily CHEMBL162 CHEMBL1980995 CHEMBL861046 (1) CHEMBL1063737 (1)
CHEMBL1908568 (1) CHEMBL1963737 (1)
0 / 0
Q9Y4K4 Mitogen-activated protein kinase kinase kinase kinase 5 STE serine/threonine protein kinase KHS subfamily CHEMBL162 CHEMBL1980995 CHEMBL860642 (1) CHEMBL1061903 (1)
CHEMBL1908758 (1) CHEMBL1963810 (1)
0 / 0
P41279 Mitogen-activated protein kinase kinase kinase 8 Ste11 CHEMBL162 CHEMBL1838336 (1)
0 / 0
Q13177 Serine/threonine-protein kinase PAK 2 STE serine/threonine protein kinase PAKA subfamily CHEMBL162 CHEMBL1021076 (1) CHEMBL1050828 (1)
CHEMBL1908569 (1) CHEMBL2219357 (1)
CHEMBL2219358 (1)
0 / 0
Q06418 Tyrosine-protein kinase receptor TYRO3 TK tyrosine-protein kinase AXL CHEMBL162 CHEMBL1980995 CHEMBL900479 (1) CHEMBL1051260 (1)
CHEMBL1211285 (1) CHEMBL1908754 (1)
CHEMBL1963714 (1) CHEMBL2219161 (1)
CHEMBL2219162 (1)
0 / 0
Q6PHR2 Serine/threonine-protein kinase ULK3 ULK serine/threonine protein kinase CHEMBL162 CHEMBL1908515 (1) CHEMBL2219323 (1)
CHEMBL2219324 (1)
0 / 0
Q7L7X3 Serine/threonine-protein kinase TAO1 STE serine/threonine protein kinase TAO subfamily CHEMBL162 CHEMBL1980995 CHEMBL1908823 (1) CHEMBL1963750 (1)
CHEMBL2219199 (1) CHEMBL2219200 (1)
0 / 0
P14616 Insulin receptor-related protein TK tyrosine-protein kinase INSR CHEMBL162 CHEMBL1061175 (1) CHEMBL1908772 (1)
CHEMBL2219223 (1) CHEMBL2219224 (1)
0 / 0
O15075 Serine/threonine-protein kinase DCLK1 CAMK serine/threonine protein kinase DCAMK1 CHEMBL162 CHEMBL1063705 (1) CHEMBL1908663 (1)
0 / 0
O43318 Mitogen-activated protein kinase kinase kinase 7 Tak1 CHEMBL162 CHEMBL973463 (1) CHEMBL1908421 (1)
CHEMBL2219197 (1) CHEMBL2219198 (1)
0 / 0
Q9BXA7 Testis-specific serine/threonine-protein kinase 1 Tssk CHEMBL162 CHEMBL1051316 (1) CHEMBL1908839 (1)
CHEMBL2219307 (1) CHEMBL2219308 (1)
0 / 0
O94921 Cyclin-dependent kinase 14 Pftaire CHEMBL162 CHEMBL1051350 (1) CHEMBL1908767 (1)
0 / 0
Q9H0K1 Serine/threonine-protein kinase SIK2 CAMK serine/threonine protein kinase QIK subfamily CHEMBL162 CHEMBL1980995 CHEMBL1061982 (1) CHEMBL1908792 (1)
CHEMBL1963784 (1)
0 / 0
Q9H2K8 Serine/threonine-protein kinase TAO3 STE serine/threonine protein kinase TAO subfamily CHEMBL162 CHEMBL1908798 (1) CHEMBL2219203 (1)
CHEMBL2219204 (1)
0 / 0
Q00537 Cyclin-dependent kinase 17 Pctaire CHEMBL162 CHEMBL1051349 (1) CHEMBL1908473 (1)
0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL1537489 CHEMBL1614038 (1)
2 / 2
O15118 Niemann-Pick C1 protein Unclassified protein CHEMBL1537489 CHEMBL1614342 (1)
1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL1537489 CHEMBL1738588 (1)
0 / 0
Q6XUX3 Dual serine/threonine and tyrosine protein kinase Enzyme CHEMBL162 CHEMBL1908455 (1)
0 / 0
Q8NG66 Serine/threonine-protein kinase Nek11 Nek11 CHEMBL162 CHEMBL1908422 (1) CHEMBL2219299 (1)
CHEMBL2219300 (1)
0 / 0
Q9Y2U5 Mitogen-activated protein kinase kinase kinase 2 STE serine/threonine protein kinase MEKK2 subfamily CHEMBL162 CHEMBL1908759 (1)
0 / 0
Q8WU08 Serine/threonine-protein kinase 32A AGC serine/threonine protein kinase YANK subfamily CHEMBL162 CHEMBL1908518 (1)
0 / 0
Q8WTQ7 G protein-coupled receptor kinase 7 AGC serine/threonine protein kinase GRK subfamily CHEMBL162 CHEMBL1908416 (1) CHEMBL2219092 (1)
CHEMBL2219093 (1)
0 / 0
Q8TF76 Serine/threonine-protein kinase haspin Haspin CHEMBL162 CHEMBL2219104 (1) CHEMBL2219105 (1)
0 / 0
Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase STE serine/threonine protein kinase FRAY subfamily CHEMBL162 CHEMBL1908768 (1)
0 / 0
O95382 Mitogen-activated protein kinase kinase kinase 6 STE serine/threonine protein kinase ASK subfamily CHEMBL162 CHEMBL1908659 (1)
0 / 0
Q9UPZ9 Serine/threonine-protein kinase ICK CMGC serine/threonine protein kinase MAK subfamily CHEMBL162 CHEMBL1908787 (1)
1 / 1
Q6ZN16 Mitogen-activated protein kinase kinase kinase 15 STE serine/threonine protein kinase ASK subfamily CHEMBL162 CHEMBL1908498 (1)
0 / 0
P11362 Fibroblast growth factor receptor 1 Fgfr CHEMBL162 CHEMBL1980995 CHEMBL676887 (1) CHEMBL860911 (1)
CHEMBL900485 (1) CHEMBL972538 (1)
CHEMBL1062840 (1) CHEMBL1908829 (1)
CHEMBL1963740 (1) CHEMBL2219062 (1)
CHEMBL2219063 (1)
4 / 5
P53350 Serine/threonine-protein kinase PLK1 PLK serine/threonine protein kinase subfamily CHEMBL162 CHEMBL1980995 CHEMBL1051311 (1) CHEMBL1908672 (1)
CHEMBL1919768 (1) CHEMBL1963829 (1)
CHEMBL2216235 (1) CHEMBL2219141 (1)
CHEMBL2219142 (1) CHEMBL2327183 (1)
CHEMBL2327184 (1) CHEMBL2327185 (1)
0 / 0
Q08881 Tyrosine-protein kinase ITK/TSK Tec CHEMBL162 CHEMBL1980995 CHEMBL1063712 (1) CHEMBL1908717 (1)
CHEMBL1963747 (1) CHEMBL2219225 (1)
CHEMBL2219226 (1)
1 / 1
P49840 Glycogen synthase kinase-3 alpha Gsk CHEMBL162 CHEMBL1980995 CHEMBL868620 (1) CHEMBL1061900 (1)
CHEMBL1908811 (1) CHEMBL1963771 (1)
CHEMBL2219094 (1) CHEMBL2219095 (1)
0 / 0
Q13976 cGMP-dependent protein kinase 1 Pkg CHEMBL162 CHEMBL1062859 (1) CHEMBL1908749 (1)
CHEMBL2219123 (1) CHEMBL2219124 (1)
CHEMBL2219125 (1) CHEMBL2219126 (1)
0 / 0
Q8IW41 MAP kinase-activated protein kinase 5 CAMK serine/threonine protein kinase MAPKAPK CHEMBL162 CHEMBL1061904 (1) CHEMBL1908620 (1)
CHEMBL2219127 (1) CHEMBL2219128 (1)
0 / 0
O75116 Rho-associated protein kinase 2 Rock CHEMBL162 CHEMBL1980995 CHEMBL1908666 (1) CHEMBL1963722 (1)
CHEMBL2219153 (1) CHEMBL2219154 (1)
0 / 0
O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Enzyme CHEMBL162 CHEMBL1908671 (1)
0 / 0
P05771 Protein kinase C beta type Alpha CHEMBL162 CHEMBL686884 (1) CHEMBL760364 (1)
CHEMBL761757 (1) CHEMBL761758 (1)
CHEMBL764570 (1) CHEMBL764575 (1)
CHEMBL764582 (1) CHEMBL768280 (1)
CHEMBL767225 (1) CHEMBL769345 (1)
CHEMBL769348 (1) CHEMBL769354 (1)
CHEMBL766548 (1) CHEMBL772645 (1)
CHEMBL767434 (1) CHEMBL767441 (1)
CHEMBL767445 (1) CHEMBL827792 (1)
CHEMBL829570 (1) CHEMBL829571 (1)
CHEMBL834104 (1) CHEMBL981182 (1)
CHEMBL2219400 (1) CHEMBL2219401 (1)
CHEMBL2219402 (1) CHEMBL2219403 (1)
0 / 0
P08631 Tyrosine-protein kinase HCK Src CHEMBL162 CHEMBL1980995 CHEMBL860887 (1) CHEMBL1063730 (1)
CHEMBL1908554 (1) CHEMBL1963709 (1)
CHEMBL2219106 (1) CHEMBL2219107 (1)
CHEMBL2219108 (1) CHEMBL2219109 (1)
0 / 0
P07948 Tyrosine-protein kinase Lyn Src CHEMBL162 CHEMBL1980995 CHEMBL860805 (1) CHEMBL973448 (1)
CHEMBL1037544 (1) CHEMBL1052171 (1)
CHEMBL1908559 (1) CHEMBL1919763 (1)
CHEMBL1963745 (1) CHEMBL2219249 (1)
CHEMBL2219250 (1)
0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt CHEMBL162 CHEMBL1980995 CHEMBL867719 (1) CHEMBL869544 (1)
CHEMBL869547 (1) CHEMBL862611 (1)
CHEMBL868840 (1) CHEMBL868852 (1)
CHEMBL868045 (1) CHEMBL868623 (1)
CHEMBL868624 (1) CHEMBL868630 (1)
CHEMBL972522 (1) CHEMBL1051279 (1)
CHEMBL1908691 (1) CHEMBL1921564 (1)
CHEMBL1963809 (1) CHEMBL2219392 (1)
CHEMBL2219393 (1)
4 / 1
O00141 Serine/threonine-protein kinase Sgk1 AGC serine/threonine protein kinase SGK subfamily CHEMBL162 CHEMBL2219179 (1) CHEMBL2219180 (1)
0 / 0
P51812 Ribosomal protein S6 kinase alpha-3 Rskb CHEMBL162 CHEMBL1980995 CHEMBL860796 (1) CHEMBL1062870 (1)
CHEMBL1908657 (1) CHEMBL1913893 (1)
CHEMBL1963690 (1) CHEMBL2219165 (1)
CHEMBL2219166 (1)
2 / 2
P07333 Macrophage colony-stimulating factor 1 receptor Pdgfr CHEMBL162 CHEMBL1980995 CHEMBL1063702 (1) CHEMBL1908692 (1)
CHEMBL1921579 (1) CHEMBL1964104 (1)
CHEMBL2219082 (1) CHEMBL2219083 (1)
1 / 1
O75716 Serine/threonine-protein kinase 16 NAK serine/threonine protein kinase subfamily CHEMBL162 CHEMBL860783 (1) CHEMBL1051353 (1)
CHEMBL1908472 (1)
0 / 0
P16591 Tyrosine-protein kinase Fer Fer CHEMBL162 CHEMBL1980995 CHEMBL860780 (1) CHEMBL1061071 (1)
CHEMBL1908707 (1) CHEMBL1963815 (1)
CHEMBL2219070 (1) CHEMBL2219071 (1)
0 / 0
P33981 Dual specificity protein kinase TTK Ttk CHEMBL162 CHEMBL860776 (1) CHEMBL1061934 (1)
CHEMBL1908607 (1)
0 / 0
Q8IU85 Calcium/calmodulin-dependent protein kinase type 1D Camk1 CHEMBL162 CHEMBL1980995 CHEMBL860659 (1) CHEMBL1052133 (1)
CHEMBL1908815 (1) CHEMBL1963811 (1)
CHEMBL2219018 (1) CHEMBL2219019 (1)
0 / 0
Q9HAZ1 Dual specificity protein kinase CLK4 Clk CHEMBL162 CHEMBL1980995 CHEMBL860652 (1) CHEMBL1061140 (1)
CHEMBL1908822 (1) CHEMBL1963837 (1)
0 / 0
Q9HC98 Serine/threonine-protein kinase Nek6 Nek CHEMBL162 CHEMBL860650 (1) CHEMBL1062858 (1)
CHEMBL1908776 (1) CHEMBL2219351 (1)
CHEMBL2219352 (1)
0 / 0
Q9UEE5 Serine/threonine-protein kinase 17A Dapk CHEMBL162 CHEMBL1980995 CHEMBL859487 (1) CHEMBL1061142 (1)
CHEMBL1908665 (1) CHEMBL1963717 (1)
CHEMBL2219030 (1) CHEMBL2219031 (1)
0 / 0
Q96EB6 NAD-dependent protein deacetylase sirtuin-1 Enzyme CHEMBL162 CHEMBL908191 (1)
0 / 0
Q8IY84 Serine/threonine-protein kinase NIM1 Nim1 CHEMBL162 CHEMBL1908425 (1)
0 / 0
P07949 Proto-oncogene tyrosine-protein kinase receptor Ret Ret CHEMBL162 CHEMBL1980995 CHEMBL973459 (1) CHEMBL1051257 (1)
CHEMBL1061179 (1) CHEMBL1908818 (1)
CHEMBL1908819 (1) CHEMBL1908820 (1)
CHEMBL1908821 (1) CHEMBL1963706 (1)
CHEMBL2219155 (1) CHEMBL2219156 (1)
9 / 5
Q9H2X6 Homeodomain-interacting protein kinase 2 CMGC dual-specificity kinase HIPK CHEMBL162 CHEMBL1980995 CHEMBL1908826 (1) CHEMBL1963754 (1)
CHEMBL2219100 (1) CHEMBL2219101 (1)
0 / 0
P36896 Activin receptor type-1B TKL serine/threonine protein kinase STKR type 1 subfamily CHEMBL162 CHEMBL1051278 (1) CHEMBL1908640 (1)
CHEMBL2219375 (1) CHEMBL2219376 (1)
0 / 0
P37023 Serine/threonine-protein kinase receptor R3 TKL serine/threonine protein kinase STKR type 1 subfamily CHEMBL162 CHEMBL1063790 (1) CHEMBL1908475 (1)
1 / 1
Q07002 Cyclin-dependent kinase 18 Pctaire CHEMBL162 CHEMBL1062782 (1) CHEMBL1908571 (1)
0 / 0
Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 STE serine/threonine protein kinase KHS subfamily CHEMBL162 CHEMBL1980995 CHEMBL1908656 (1) CHEMBL1963772 (1)
0 / 0
Q15046 Lysine--tRNA ligase Enzyme CHEMBL162 CHEMBL981176 (1)
2 / 1
Q15835 Rhodopsin kinase AGC serine/threonine protein kinase GRK subfamily CHEMBL162 CHEMBL1908595 (1)
1 / 1
Q9Y616 Interleukin-1 receptor-associated kinase 3 Irak CHEMBL162 CHEMBL1062842 (1) CHEMBL1908763 (1)
1 / 0
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor CHEMBL1537489 CHEMBL1614052 (1)
1 / 0
Q86UE8 Serine/threonine-protein kinase tousled-like 2 TLK serine/threonine protein kinase CHEMBL162 CHEMBL1061984 (1) CHEMBL1908468 (1)
CHEMBL2219305 (1) CHEMBL2219306 (1)
0 / 0
Q86UX6 Serine/threonine-protein kinase 32C AGC serine/threonine protein kinase YANK CHEMBL162 CHEMBL1062789 (1) CHEMBL1908431 (1)
0 / 0
Q86Z02 Homeodomain-interacting protein kinase 1 CMGC serine/threonine protein kinase HIPK subfamily CHEMBL162 CHEMBL972545 (1) CHEMBL1908423 (1)
CHEMBL2219098 (1) CHEMBL2219099 (1)
0 / 0
Q8IVH8 Mitogen-activated protein kinase kinase kinase kinase 3 STE serine/threonine protein kinase KHS subfamily CHEMBL162 CHEMBL1063715 (1) CHEMBL1908618 (1)
0 / 0
Q8NFD2 Ankyrin repeat and protein kinase domain-containing protein 1 TKL serine/threonine protein kinase RIPK subfamily CHEMBL162 CHEMBL1060235 (1) CHEMBL1908432 (1)
0 / 0
Q99759 Mitogen-activated protein kinase kinase kinase 3 Mekk2 CHEMBL162 CHEMBL1908562 (1)
0 / 0
O75385 Serine/threonine-protein kinase ULK1 ULK serine/threonine protein kinase CHEMBL162 CHEMBL1908613 (1)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL388978 CHEMBL1537489 CHEMBL1614211 (2)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL388978 CHEMBL1537489 CHEMBL1614250 (3) CHEMBL1614421 (3)
CHEMBL1614502 (3)
4 / 3
Q12852 Mitogen-activated protein kinase kinase kinase 12 Enzyme CHEMBL162 CHEMBL1908459 (1)
0 / 0
P21860 Receptor tyrosine-protein kinase erbB-3 TK tyrosine-protein kinase EGFR subfamily CHEMBL162 CHEMBL1908548 (1)
1 / 2
Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 TKL serine/threonine protein kinase LRRK subfamily CHEMBL162 CHEMBL1980995 CHEMBL1908437 (1) CHEMBL1908438 (1)
CHEMBL1963806 (1)
2 / 2
O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 Enzyme CHEMBL162 CHEMBL1908532 (1)
0 / 0
O95747 Serine/threonine-protein kinase OSR1 STE serine/threonine protein kinase FRAY subfamily CHEMBL162 CHEMBL1908674 (1)
0 / 0
Q52WX2 Serine/threonine-protein kinase SBK1 NKF1 serine/threonine protein kinase subfamily CHEMBL162 CHEMBL1908509 (1)
0 / 0
P10721 Mast/stem cell growth factor receptor Kit Pdgfr CHEMBL162 CHEMBL1980995 CHEMBL860918 (1) CHEMBL869542 (1)
CHEMBL864429 (1) CHEMBL868611 (1)
CHEMBL901554 (1) CHEMBL1061077 (1)
CHEMBL1060197 (1) CHEMBL1060198 (1)
CHEMBL1051336 (1) CHEMBL1061901 (1)
CHEMBL1787525 (1) CHEMBL1908483 (1)
CHEMBL1908484 (1) CHEMBL1908485 (1)
CHEMBL1908486 (1) CHEMBL1908487 (1)
CHEMBL1908488 (1) CHEMBL1908489 (1)
CHEMBL1908490 (1) CHEMBL1921570 (1)
CHEMBL1963734 (1) CHEMBL2219339 (1)
CHEMBL2219340 (1)
4 / 4
P06239 Tyrosine-protein kinase Lck Src CHEMBL162 CHEMBL1980995 CHEMBL823226 (1) CHEMBL860915 (1)
CHEMBL981181 (1) CHEMBL973447 (1)
CHEMBL1051337 (1) CHEMBL1052173 (1)
CHEMBL1908710 (1) CHEMBL1913941 (1)
CHEMBL1919762 (1) CHEMBL1963718 (1)
CHEMBL2216237 (1) CHEMBL2219245 (1)
CHEMBL2219246 (1) CHEMBL2219247 (1)
CHEMBL2219248 (1)
0 / 1
Q9HCP0 Casein kinase I isoform gamma-1 Ck1 CHEMBL162 CHEMBL658117 (1) CHEMBL860913 (1)
CHEMBL1060186 (1) CHEMBL1908825 (1)
CHEMBL2218990 (1) CHEMBL2218991 (1)
0 / 0
Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta Camk2 CHEMBL162 CHEMBL657561 (1) CHEMBL653818 (1)
CHEMBL767435 (1) CHEMBL860910 (1)
CHEMBL972525 (1) CHEMBL1060183 (1)
CHEMBL1908524 (1) CHEMBL2219010 (1)
CHEMBL2219011 (1)
0 / 0
O96017 Serine/threonine-protein kinase Chk2 Rad53 CHEMBL162 CHEMBL1980995 CHEMBL972529 (1) CHEMBL1051603 (1)
CHEMBL1068399 (1) CHEMBL1764344 (1)
CHEMBL1908500 (1) CHEMBL1913731 (1)
CHEMBL1930051 (1) CHEMBL1963720 (1)
CHEMBL2218988 (1) CHEMBL2218989 (1)
4 / 1
P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 Ampk CHEMBL162 CHEMBL1060176 (1) CHEMBL1908744 (1)
CHEMBL2219379 (1) CHEMBL2219380 (1)
0 / 0
P52333 Tyrosine-protein kinase JAK3 Jakb CHEMBL162 CHEMBL1980995 CHEMBL889938 (1) CHEMBL901551 (1)
CHEMBL973445 (1) CHEMBL1053840 (1)
CHEMBL1051335 (1) CHEMBL1908482 (1)
CHEMBL1919759 (1) CHEMBL1963742 (1)
CHEMBL2219229 (1) CHEMBL2219230 (1)
1 / 1
O94806 Serine/threonine-protein kinase D3 Pkd CHEMBL162 CHEMBL1980995 CHEMBL760364 (1) CHEMBL767225 (1)
CHEMBL769345 (1) CHEMBL769348 (1)
CHEMBL769354 (1) CHEMBL766548 (1)
CHEMBL772645 (1) CHEMBL767434 (1)
CHEMBL767441 (1) CHEMBL767445 (1)
CHEMBL827792 (1) CHEMBL1062866 (1)
CHEMBL1908721 (1) CHEMBL1963715 (1)
0 / 0
P04049 RAF proto-oncogene serine/threonine-protein kinase Raf CHEMBL162 CHEMBL388978 CHEMBL769165 (1) CHEMBL868621 (1)
CHEMBL963404 (1) CHEMBL1062868 (1)
CHEMBL1613772 (1) CHEMBL1908594 (1)
CHEMBL2219337 (1) CHEMBL2219338 (1)
CHEMBL2343187 (1)
2 / 0
P43405 Tyrosine-protein kinase SYK Syk CHEMBL162 CHEMBL1980995 CHEMBL860905 (1) CHEMBL901556 (1)
CHEMBL973462 (1) CHEMBL1022010 (1)
CHEMBL992587 (1) CHEMBL1061186 (1)
CHEMBL1908604 (1) CHEMBL1919772 (1)
CHEMBL1963712 (1) CHEMBL2219195 (1)
CHEMBL2219196 (1)
0 / 0
Q14012 Calcium/calmodulin-dependent protein kinase type 1 Camk1 CHEMBL162 CHEMBL1980995 CHEMBL860901 (1) CHEMBL1060239 (1)
CHEMBL1908619 (1) CHEMBL1963816 (1)
CHEMBL2219008 (1) CHEMBL2219009 (1)
0 / 0
Q16566 Calcium/calmodulin-dependent protein kinase type IV Camk1 CHEMBL162 CHEMBL1060179 (1) CHEMBL1908540 (1)
CHEMBL2219016 (1) CHEMBL2219017 (1)
0 / 0
P53355 Death-associated protein kinase 1 Dapk CHEMBL162 CHEMBL972532 (1) CHEMBL1044652 (1)
CHEMBL1908668 (1) CHEMBL2219020 (1)
CHEMBL2219021 (1)
0 / 1
P24723 Protein kinase C eta type Eta CHEMBL162 CHEMBL760364 (1) CHEMBL770091 (1)
CHEMBL770095 (1) CHEMBL767225 (1)
CHEMBL769345 (1) CHEMBL769348 (1)
CHEMBL769354 (1) CHEMBL766548 (1)
CHEMBL772645 (1) CHEMBL767434 (1)
CHEMBL767441 (1) CHEMBL767445 (1)
CHEMBL827792 (1) CHEMBL1050833 (1)
CHEMBL1060261 (1) CHEMBL1908746 (1)
CHEMBL2219113 (1) CHEMBL2219114 (1)
1 / 0
P51451 Tyrosine-protein kinase Blk Src CHEMBL162 CHEMBL1980995 CHEMBL1063791 (1) CHEMBL1908538 (1)
CHEMBL1963752 (1) CHEMBL2218960 (1)
CHEMBL2218961 (1)
1 / 1
P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Enzyme CHEMBL162 CHEMBL1908576 (1)
0 / 0
P17612 cAMP-dependent protein kinase catalytic subunit alpha Pka CHEMBL162 CHEMBL1709437 CHEMBL1980995 CHEMBL769033 (1) CHEMBL769034 (1)
CHEMBL772601 (1) CHEMBL772604 (1)
CHEMBL772605 (1) CHEMBL767993 (1)
CHEMBL767996 (1) CHEMBL768001 (1)
CHEMBL869531 (1) CHEMBL864414 (1)
CHEMBL868610 (1) CHEMBL1051309 (1)
CHEMBL1738330 (1) CHEMBL1908578 (1)
CHEMBL1963835 (1) CHEMBL2219390 (1)
CHEMBL2219391 (1)
0 / 0
Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A CMGC dual-specificity kinase DYRK1 CHEMBL162 CHEMBL1980995 CHEMBL1908409 (1) CHEMBL1964107 (1)
1 / 0
Q13233 Mitogen-activated protein kinase kinase kinase 1 Ste11 CHEMBL162 CHEMBL1908723 (1)
1 / 0
O14746 Telomerase reverse transcriptase Enzyme CHEMBL162 CHEMBL1918611 (1) CHEMBL2160525 (1)
CHEMBL2319538 (1)
5 / 5
O14733 Dual specificity mitogen-activated protein kinase kinase 7 Ste7 CHEMBL162 CHEMBL1908419 (1) CHEMBL2219269 (1)
CHEMBL2219270 (1)
0 / 0
P53778 Mitogen-activated protein kinase 12 p38 CHEMBL162 CHEMBL1980995 CHEMBL732633 (1) CHEMBL859643 (1)
CHEMBL1061183 (1) CHEMBL1908463 (1)
CHEMBL1963836 (1) CHEMBL2219175 (1)
CHEMBL2219176 (1)
0 / 0
O00418 Eukaryotic elongation factor 2 kinase Atypical serine/threonine protein kinase alpha subfamily CHEMBL162 CHEMBL1980995 CHEMBL1963711 (1) CHEMBL2219343 (1)
CHEMBL2219344 (1)
0 / 0
P35557 Glucokinase Enzyme CHEMBL162 CHEMBL2219086 (1) CHEMBL2219087 (1)
3 / 3
P49760 Dual specificity protein kinase CLK2 Clk CHEMBL162 CHEMBL1980995 CHEMBL860773 (1) CHEMBL1061139 (1)
CHEMBL1908629 (1) CHEMBL1963691 (1)
CHEMBL2219002 (1) CHEMBL2219003 (1)
0 / 0
P54756 Ephrin type-A receptor 5 Eph CHEMBL162 CHEMBL860666 (1) CHEMBL1061069 (1)
CHEMBL1908434 (1) CHEMBL2219044 (1)
CHEMBL2219045 (1)
0 / 0
P54762 Ephrin type-B receptor 1 Eph CHEMBL162 CHEMBL860665 (1) CHEMBL1060191 (1)
CHEMBL1908651 (1) CHEMBL2219050 (1)
CHEMBL2219051 (1)
0 / 0
Q07912 Activated CDC42 kinase 1 TK tyrosine-protein kinase ACK subfamily CHEMBL162 CHEMBL1980995 CHEMBL860662 (1) CHEMBL900478 (1)
CHEMBL1051355 (1) CHEMBL1908504 (1)
CHEMBL1963777 (1) CHEMBL2219371 (1)
CHEMBL2219372 (1)
0 / 0
Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 Ste11 CHEMBL162 CHEMBL860641 (1) CHEMBL1062844 (1)
CHEMBL1908724 (1)
0 / 0
P30530 Tyrosine-protein kinase receptor UFO TK tyrosine-protein kinase AXL subfamily CHEMBL162 CHEMBL1060237 (1) CHEMBL1908537 (1)
CHEMBL2218954 (1) CHEMBL2218955 (1)
0 / 0
Q9BZL6 Serine/threonine-protein kinase D2 Pkd CHEMBL162 CHEMBL1980995 CHEMBL1061156 (1) CHEMBL1908799 (1)
CHEMBL1963707 (1) CHEMBL2219121 (1)
CHEMBL2219122 (1)
0 / 0
Q8TD08 Mitogen-activated protein kinase 15 Mapk CHEMBL162 CHEMBL1060193 (1) CHEMBL1908412 (1)
0 / 0
P37173 TGF-beta receptor type-2 TKL dual-specificity kinase STKR type 2 subfamily CHEMBL162 CHEMBL1051354 (1) CHEMBL1908606 (1)
4 / 3
Q86V86 Serine/threonine-protein kinase pim-3 Pim CHEMBL162 CHEMBL1051340 (1) CHEMBL1908499 (1)
CHEMBL2219139 (1) CHEMBL2219140 (1)
0 / 0
P36894 Bone morphogenetic protein receptor type-1A TKL serine/threonine protein kinase STKR type 1 subfamily CHEMBL162 CHEMBL1063699 (1) CHEMBL1908642 (1)
3 / 2
Q9UPE1 SRSF protein kinase 3 Srpk CHEMBL162 CHEMBL1908775 (1) CHEMBL2219283 (1)
CHEMBL2219284 (1)
0 / 0
Q15569 Dual specificity testis-specific protein kinase 1 TKL dual-specificity kinase TESK subfamily CHEMBL162 CHEMBL1037550 (1) CHEMBL1908753 (1)
0 / 0
Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 Unclassified protein CHEMBL162 CHEMBL973464 (1)
0 / 0
Q16288 NT-3 growth factor receptor Trk CHEMBL162 CHEMBL1980995 CHEMBL1041998 (1) CHEMBL1908462 (1)
CHEMBL1963688 (1)
0 / 1
Q9Y6E0 Serine/threonine-protein kinase 24 STE serine/threonine protein kinase YSK subfamily CHEMBL162 CHEMBL1062845 (1) CHEMBL1908614 (1)
CHEMBL2219289 (1) CHEMBL2219290 (1)
0 / 0
Q9Y6M4 Casein kinase I isoform gamma-3 Ck1-g CHEMBL162 CHEMBL1051284 (1) CHEMBL1908646 (1)
CHEMBL2218994 (1) CHEMBL2218995 (1)
0 / 0
O00238 Bone morphogenetic protein receptor type-1B TKL serine/threonine protein kinase STKR type 1 subfamily CHEMBL162 CHEMBL1908522 (1)
2 / 2
Q8N568 Serine/threonine-protein kinase DCLK2 CAMK serine/threonine protein kinase DCAMK1 CHEMBL162 CHEMBL1063795 (1) CHEMBL1908511 (1)
CHEMBL2219024 (1) CHEMBL2219025 (1)
0 / 0
Q8TDC3 Serine/threonine-protein kinase BRSK1 CAMK serine/threonine protein kinase BRSK subfamily CHEMBL162 CHEMBL1061135 (1) CHEMBL1908399 (1)
CHEMBL2218964 (1) CHEMBL2218965 (1)
0 / 0
Q96D53 Uncharacterized aarF domain-containing protein kinase 4 Atypical serine/threonine protein kinase ABC1-A CHEMBL162 CHEMBL1061132 (1) CHEMBL1908832 (1)
0 / 0
Q96L34 MAP/microtubule affinity-regulating kinase 4 CAMK serine/threonine protein kinase MARK subfamily CHEMBL162 CHEMBL1980995 CHEMBL1051302 (1) CHEMBL1908837 (1)
CHEMBL1963713 (1)
0 / 0
P19525 Interferon-induced, double-stranded RNA-activated protein kinase Pkr CHEMBL162 CHEMBL388978 CHEMBL1062867 (1) CHEMBL1805140 (1)
CHEMBL1908593 (1)
0 / 0
P51817 cAMP-dependent protein kinase catalytic subunit PRKX Pka CHEMBL162 CHEMBL1980995 CHEMBL1061157 (1) CHEMBL1908673 (1)
CHEMBL1963800 (1) CHEMBL2219145 (1)
CHEMBL2219146 (1)
0 / 0
Q9BRS2 Serine/threonine-protein kinase RIO1 Rio1 CHEMBL162 CHEMBL1051258 (1) CHEMBL1908838 (1)
0 / 0
O95835 Serine/threonine-protein kinase LATS1 AGC serine/threonine protein kinase NDR CHEMBL162 CHEMBL1062843 (1) CHEMBL1908660 (1)
0 / 0
P31152 Mitogen-activated protein kinase 4 CMGC serine/threonine protein kinase ERK3 subfamily CHEMBL162 CHEMBL1060245 (1) CHEMBL1908583 (1)
0 / 0
Q9NY57 Serine/threonine-protein kinase 32B AGC serine/threonine protein kinase YANK CHEMBL162 CHEMBL1061985 (1) CHEMBL1908809 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL1537489 CHEMBL1613914 (1)
0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme CHEMBL388978 CHEMBL1537489 CHEMBL1613829 (2)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL1537489 CHEMBL1738442 (1)
0 / 0
O15197 Ephrin type-B receptor 6 Unclassified protein CHEMBL162 CHEMBL1908654 (1)
0 / 0
Q9UL54 Serine/threonine-protein kinase TAO2 STE serine/threonine protein kinase TAO subfamily CHEMBL162 CHEMBL1908796 (1) CHEMBL2219201 (1)
CHEMBL2219202 (1)
0 / 0
Q8IVW4 Cyclin-dependent kinase-like 3 CMGC serine/threonine protein kinase CDKL subfamily CHEMBL162 CHEMBL1908519 (1)
0 / 0
Q9Y2H9 Microtubule-associated serine/threonine-protein kinase 1 AGC serine/threonine protein kinase MAST CHEMBL162 CHEMBL1908788 (1)
0 / 0
O00255 Menin Unclassified protein CHEMBL388978 CHEMBL1537489 CHEMBL1614257 (2)
2 / 5
P51946 Cyclin-H Other cytosolic protein CHEMBL162 CHEMBL2218982 (1) CHEMBL2218983 (1)
0 / 0
O96020 G1/S-specific cyclin-E2 Other cytosolic protein CHEMBL162 CHEMBL665283 (1) CHEMBL664632 (1)
CHEMBL831687 (1) CHEMBL2218972 (1)
CHEMBL2218973 (1) CHEMBL2218974 (1)
CHEMBL2218975 (1)
0 / 2
O95067 G2/mitotic-specific cyclin-B2 Other cytosolic protein CHEMBL162 CHEMBL666084 (1) CHEMBL831686 (1)
CHEMBL1249832 (1) CHEMBL1250275 (1)
CHEMBL2218968 (1) CHEMBL2218969 (1)
0 / 0
Q8WWL7 G2/mitotic-specific cyclin-B3 Other cytosolic protein CHEMBL162 CHEMBL666084 (1) CHEMBL831686 (1)
CHEMBL1249832 (1) CHEMBL1250275 (1)
CHEMBL2218968 (1) CHEMBL2218969 (1)
0 / 0
P20248 Cyclin-A2 Other cytosolic protein CHEMBL162 CHEMBL2218970 (1) CHEMBL2218971 (1)
CHEMBL2320996 (1) CHEMBL2320998 (1)
0 / 0
P78396 Cyclin-A1 Other cytosolic protein CHEMBL162 CHEMBL2218970 (1) CHEMBL2218971 (1)
CHEMBL2320996 (1) CHEMBL2320998 (1)
0 / 0
P22612 cAMP-dependent protein kinase catalytic subunit gamma Pka CHEMBL162 CHEMBL769033 (1) CHEMBL769034 (1)
CHEMBL772601 (1) CHEMBL772604 (1)
CHEMBL772605 (1) CHEMBL767993 (1)
CHEMBL767996 (1) CHEMBL768001 (1)
CHEMBL869531 (1) CHEMBL864414 (1)
CHEMBL868610 (1)
0 / 0
P67870 Casein kinase II subunit beta REG serine/threonine protein kinase family CHEMBL162 CHEMBL659493 (1) CHEMBL869538 (1)
CHEMBL864420 (1) CHEMBL2218998 (1)
CHEMBL2218999 (1)
0 / 0
P54619 5'-AMP-activated protein kinase subunit gamma-1 REG serine/threonine protein kinase family CHEMBL162 CHEMBL2219377 (1) CHEMBL2219378 (1)
CHEMBL2219379 (1) CHEMBL2219380 (1)
0 / 0
Q9Y478 5'-AMP-activated protein kinase subunit beta-1 REG serine/threonine protein kinase family CHEMBL162 CHEMBL2219377 (1) CHEMBL2219378 (1)
CHEMBL2219379 (1) CHEMBL2219380 (1)
0 / 0
O43741 5'-AMP-activated protein kinase subunit beta-2 REG serine/threonine protein kinase family CHEMBL162 CHEMBL2219379 (1) CHEMBL2219380 (1)
0 / 0
Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 REG serine/threonine protein kinase family CHEMBL162 CHEMBL2219379 (1) CHEMBL2219380 (1)
3 / 3
Q93100 Phosphorylase b kinase regulatory subunit beta REG serine/threonine protein kinase family CHEMBL162 CHEMBL765147 (1)
1 / 1
P46020 Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform REG serine/threonine protein kinase family CHEMBL162 CHEMBL765147 (1)
1 / 1
P46019 Phosphorylase b kinase regulatory subunit alpha, liver isoform REG serine/threonine protein kinase family CHEMBL162 CHEMBL765147 (1)
1 / 1
O60563 Cyclin-T1 Other cytosolic protein CHEMBL162 CHEMBL2218984 (1) CHEMBL2218985 (1)
CHEMBL2320997 (1) CHEMBL2320999 (1)
0 / 0
P30281 G1/S-specific cyclin-D3 Other cytosolic protein CHEMBL162 CHEMBL2218980 (1) CHEMBL2218981 (1)
0 / 1
P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A Isomerase CHEMBL162 CHEMBL2219347 (1) CHEMBL2219348 (1)
0 / 0
Q01538 Myelin transcription factor 1 Unclassified protein CHEMBL162 CHEMBL2341275 (1) CHEMBL2341276 (1)
0 / 0
Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 Kinase CHEMBL162 CHEMBL2219379 (1) CHEMBL2219380 (1)
0 / 0

CTD interaction (124)

compound gene gene name gene description interaction interaction type form reference
pmid
D019311 8647 ABCB11
ABC16
BRIC2
BSEP
PFIC-2
PFIC2
PGY4
SPGP
ATP-binding cassette, sub-family B (MDR/TAP), member 11 Staurosporine results in decreased activity of ABCB11 protein decreases activity
protein 20829430
D019311 43 ACHE
ACEE
ARACHE
N-ACHE
YT
acetylcholinesterase (EC:3.1.1.7) ACHE protein affects the susceptibility to [Staurosporine results in increased activity of CASP9 protein] affects response to substance
/ increases activity
protein 20338155
D019311 43 ACHE
ACEE
ARACHE
N-ACHE
YT
acetylcholinesterase (EC:3.1.1.7) Staurosporine results in increased activity of ACHE protein increases activity
protein 20338155
D019311 43 ACHE
ACEE
ARACHE
N-ACHE
YT
acetylcholinesterase (EC:3.1.1.7) Staurosporine results in increased expression of ACHE protein alternative form increases expression
protein 20338155
D019311 133 ADM
AM
adrenomedullin Staurosporine results in decreased expression of ADM mRNA decreases expression
mRNA 19253104
D019311 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Staurosporine inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of AKT1 protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 15177934
D019311 351 APP
AAA
ABETA
ABPP
AD1
APPI
CTFgamma
CVAP
PN-II
PN2
amyloid beta (A4) precursor protein Staurosporine inhibits the reaction [Ginkgo biloba extract 761 inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]] decreases phosphorylation
/ decreases reaction
protein 18001288
D019311 351 APP
AAA
ABETA
ABPP
AD1
APPI
CTFgamma
CVAP
PN-II
PN2
amyloid beta (A4) precursor protein Staurosporine promotes the reaction [PSEN2 protein mutant form results in increased expression of APP protein] increases expression
/ increases reaction
protein 12556443
D019311 9140 ATG12
APG12
APG12L
FBR93
HAPG12
autophagy related 12 ATG12 protein affects the susceptibility to Staurosporine affects response to substance
protein 16497721
D019311 10533 ATG7
APG7-LIKE
APG7L
GSA7
autophagy related 7 ATG7 protein affects the susceptibility to Staurosporine affects response to substance
protein 16497721
D019311 9531 BAG3
BAG-3
BIS
CAIR-1
MFM6
BCL2-associated athanogene 3 BAG3 protein results in decreased susceptibility to Staurosporine decreases response to substance
protein 19352495
D019311 9531 BAG3
BAG-3
BIS
CAIR-1
MFM6
BCL2-associated athanogene 3 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Staurosporine results in increased degradation of BAG3 protein] decreases reaction
/ increases degradation
protein 19352495
D019311 9531 BAG3
BAG-3
BIS
CAIR-1
MFM6
BCL2-associated athanogene 3 Staurosporine results in decreased expression of BAG3 protein decreases expression
protein 19352495
D019311 9531 BAG3
BAG-3
BIS
CAIR-1
MFM6
BCL2-associated athanogene 3 Staurosporine results in increased degradation of and results in increased ubiquitination of BAG3 protein increases degradation
/ increases ubiquitination
protein 19352495
D019311 9530 BAG4
BAG-4
SODD
BCL2-associated athanogene 4 Staurosporine results in decreased expression of BAG4 protein decreases expression
protein 19352495
D019311 7917 BAG6
BAG-6
BAT3
D6S52E
G3
BCL2-associated athanogene 6 Staurosporine results in decreased expression of BAG6 protein decreases expression
protein 19352495
D019311 581 BAX
BCL2L4
BCL2-associated X protein Staurosporine affects the folding of and results in increased activity of BAX protein affects folding
/ increases activity
protein 16007140
D019311 581 BAX
BCL2L4
BCL2-associated X protein Staurosporine promotes the reaction [BID protein binds to BAX protein] affects binding
/ increases reaction
protein 19552762
D019311 581 BAX
BCL2L4
BCL2-associated X protein Staurosporine results in increased activity of and results in increased expression of BAX protein increases activity
/ increases expression
protein 19552762
D019311 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Staurosporine inhibits the reaction [Paclitaxel results in increased phosphorylation of BCL2 protein] decreases reaction
/ increases phosphorylation
protein 15907805
D019311 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 BCL2L1 protein results in decreased susceptibility to Staurosporine decreases response to substance
protein 11468182
D019311 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 Staurosporine results in increased expression of BCL2L1 protein alternative form increases expression
protein 21256112
D019311 8678 BECN1
ATG6
VPS30
beclin1
beclin 1, autophagy related 3-methyladenine inhibits the reaction [BECN1 protein results in decreased susceptibility to Staurosporine] decreases reaction
/ decreases response to substance
protein 16497721
D019311 8678 BECN1
ATG6
VPS30
beclin1
beclin 1, autophagy related BECN1 protein results in decreased susceptibility to Staurosporine decreases response to substance
protein 16497721
D019311 637 BID
FP497
BH3 interacting domain death agonist Staurosporine promotes the reaction [BID protein binds to BAX protein] affects binding
/ increases reaction
protein 19552762
D019311 637 BID
FP497
BH3 interacting domain death agonist Staurosporine results in increased expression of BID protein increases expression
protein 19552762
D019311 330 BIRC3
AIP1
API2
CIAP2
HAIP1
HIAP1
MALT2
MIHC
RNF49
c-IAP2
baculoviral IAP repeat containing 3 BIRC3 protein results in decreased susceptibility to Staurosporine decreases response to substance
protein 16144937
D019311 332 BIRC5
API4
EPR-1
baculoviral IAP repeat containing 5 Staurosporine results in decreased expression of BIRC5 protein decreases expression
protein 16225760
D019311 834 CASP1
ICE
IL1BC
P45
caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36) Nicotine affects the reaction [Staurosporine affects the localization of CASP1 protein] affects localization
/ affects reaction
protein 16927020
D019311 834 CASP1
ICE
IL1BC
P45
caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36) Nicotine inhibits the reaction [Staurosporine results in increased activity of CASP1 protein] decreases reaction
/ increases activity
protein 16927020
D019311 834 CASP1
ICE
IL1BC
P45
caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36) Staurosporine affects the localization of CASP1 protein affects localization
protein 16927020
D019311 834 CASP1
ICE
IL1BC
P45
caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36) Staurosporine results in increased activity of CASP1 protein increases activity
protein 16927020
D019311 843 CASP10
ALPS2
FLICE2
MCH4
caspase 10, apoptosis-related cysteine peptidase (EC:3.4.22.63) Staurosporine results in increased activity of CASP10 protein increases activity
protein 19352495
D019311 835 CASP2
CASP-2
ICH1
NEDD-2
NEDD2
PPP1R57
caspase 2, apoptosis-related cysteine peptidase (EC:3.4.22.55) Staurosporine results in increased cleavage of CASP2 protein increases cleavage
protein 10663630
D019311 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Acetaminophen promotes the reaction [Staurosporine results in increased activity of CASP3 protein] increases activity
/ increases reaction
protein 17245372
D019311 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Lithium Chloride inhibits the reaction [Staurosporine results in increased activity of CASP3 protein] decreases reaction
/ increases activity
protein 19101580
D019311 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Memantine inhibits the reaction [Staurosporine results in increased activity of CASP3 protein] decreases reaction
/ increases activity
protein 17996985
D019311 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) pifithrin inhibits the reaction [PSEN2 protein mutant form promotes the reaction [Staurosporine results in increased activity of CASP3 protein]] decreases reaction
/ increases activity
/ increases reaction
protein 12556443
D019311 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) PSEN2 protein mutant form promotes the reaction [Staurosporine results in increased activity of CASP3 protein] increases activity
/ increases reaction
protein 12556443
D019311 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Staurosporine results in increased activity of CASP3 protein increases activity
protein 10663630
12871656
16225760
16402917
17051331
17245372
17996985
18218830
18832097
19101580
19352495
21864672
D019311 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Staurosporine results in increased cleavage of and results in increased activity of CASP3 protein increases activity
/ increases cleavage
protein 16007152
D019311 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Staurosporine results in increased cleavage of CASP3 protein increases cleavage
protein 18178165
D019311 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Thiopental inhibits the reaction [Staurosporine results in increased activity of CASP3 protein] decreases reaction
/ increases activity
protein 18218830
D019311 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Valproic Acid inhibits the reaction [Staurosporine results in increased activity of CASP3 protein] decreases reaction
/ increases activity
protein 19101580
D019311 840 CASP7
CASP-7
CMH-1
ICE-LAP3
LICE2
MCH3
caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) Staurosporine results in increased activity of CASP7 protein increases activity
protein 16402917
18832097
19352495
21864672
D019311 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) Staurosporine results in increased activity of CASP8 protein increases activity
protein 19352495
D019311 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) Staurosporine results in increased cleavage of and results in increased activity of CASP8 protein increases activity
/ increases cleavage
protein 16007152
D019311 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) ACHE protein affects the susceptibility to [Staurosporine results in increased activity of CASP9 protein] affects response to substance
/ increases activity
protein 20338155
D019311 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) Staurosporine results in increased activity of CASP9 protein increases activity
protein 19352495
20338155
D019311 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) Staurosporine results in increased cleavage of and results in increased activity of CASP9 protein increases activity
/ increases cleavage
protein 16007152
D019311 940 CD28
Tp44
CD28 molecule Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD28 protein] decreases reaction
/ increases expression
protein 11465111
D019311 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein] decreases reaction
/ increases expression
protein 15978937
D019311 1027 CDKN1B
CDKN4
KIP1
MEN1B
MEN4
P27KIP1
cyclin-dependent kinase inhibitor 1B (p27, Kip1) Staurosporine inhibits the reaction [Tretinoin results in increased phosphorylation of CDKN1B protein] decreases reaction
/ increases phosphorylation
protein 16618747
D019311 1128 CHRM1
HM1
M1
M1R
cholinergic receptor, muscarinic 1 Staurosporine affects the reaction [KT 5720 promotes the reaction [N-Methylscopolamine binds to CHRM1 protein]] affects binding
/ affects reaction
/ increases reaction
protein 10860942
D019311 1128 CHRM1
HM1
M1
M1R
cholinergic receptor, muscarinic 1 Staurosporine affects the reaction [muscarinic toxin 7 binds to CHRM1 protein] affects binding
/ affects reaction
protein 16439611
D019311 1128 CHRM1
HM1
M1
M1R
cholinergic receptor, muscarinic 1 Staurosporine binds to CHRM1 protein affects binding
protein 10860942
D019311 1128 CHRM1
HM1
M1
M1R
cholinergic receptor, muscarinic 1 Staurosporine promotes the reaction [N-Methylscopolamine binds to CHRM1 protein] affects binding
/ increases reaction
protein 10860942
D019311 1129 CHRM2
HM2
cholinergic receptor, muscarinic 2 Staurosporine promotes the reaction [N-Methylscopolamine binds to CHRM2 protein] affects binding
/ increases reaction
protein 10860942
D019311 1385 CREB1
CREB
cAMP responsive element binding protein 1 Staurosporine inhibits the reaction [Ginkgo biloba extract 761 inhibits the reaction [APP protein results in decreased phosphorylation of CREB1 protein]] decreases phosphorylation
/ decreases reaction
protein 18001288
D019311 1437 CSF2
GMCSF
colony stimulating factor 2 (granulocyte-macrophage) CSF2 protein affects the susceptibility to [Nitroblue Tetrazolium co-treated with Staurosporine] affects cotreatment
/ affects response to substance
protein 8471626
D019311 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Staurosporine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] decreases reaction
/ increases expression
mRNA 10696073
15947024
D019311 1576 CYP3A4
CP33
CP34
CYP3A
CYP3A3
CYPIIIA3
CYPIIIA4
HLP
NF-25
P450C3
P450PCN1
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) Staurosporine inhibits the reaction [Calcitriol results in increased expression of CYP3A4 mRNA] decreases reaction
/ increases expression
mRNA 17965521
D019311 1950 EGF
HOMG4
URG
epidermal growth factor Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]]] affects binding
/ decreases reaction
protein 15542774
D019311 1950 EGF
HOMG4
URG
epidermal growth factor Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of MAPK1 protein]] decreases reaction
/ increases activity
/ increases localization
/ increases phosphorylation
protein 15542774
D019311 1950 EGF
HOMG4
URG
epidermal growth factor Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of MAPK3 protein]] decreases reaction
/ increases activity
/ increases localization
/ increases phosphorylation
protein 15542774
D019311 1950 EGF
HOMG4
URG
epidermal growth factor Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein]] decreases reaction
/ increases activity
/ increases localization
/ increases phosphorylation
protein 15542774
D019311 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) Staurosporine inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 15177934
D019311 2152 F3
CD142
TF
TFA
coagulation factor III (thromboplastin, tissue factor) Staurosporine inhibits the reaction [Asbestos, Crocidolite results in increased expression of F3 mRNA] decreases reaction
/ increases expression
mRNA 15371228
D019311 2729 GCLC
GCL
GCS
GLCL
GLCLC
glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) Staurosporine promotes the reaction [MYC protein binds to GCLC promoter] affects binding
/ increases reaction
promoter 17628013
D019311 2730 GCLM
GLCLR
glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) Staurosporine promotes the reaction [MYC protein binds to GCLM promoter] affects binding
/ increases reaction
promoter 17628013
D019311 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Staurosporine inhibits the reaction [Acrolein results in increased expression of HMOX1 mRNA] decreases reaction
/ increases expression
mRNA 18048804
D019311 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Staurosporine inhibits the reaction [VEGFA protein results in increased expression of HMOX1 protein] decreases reaction
/ increases expression
protein 12788823
D019311 3567 IL5
EDF
IL-5
TRF
interleukin 5 (colony-stimulating factor, eosinophil) Staurosporine results in decreased activity of IL5 protein decreases activity
protein 12562334
D019311 3689 ITGB2
CD18
LAD
LCAMB
LFA-1
MAC-1
MF17
MFI7
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein] decreases reaction
/ increases expression
protein 16393473
D019311 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of MAPK1 protein]] decreases reaction
/ increases activity
/ increases localization
/ increases phosphorylation
protein 15542774
D019311 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Staurosporine inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases phosphorylation
protein 16251475
D019311 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Staurosporine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases phosphorylation
protein 19699794
D019311 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Staurosporine inhibits the reaction [Nicotine results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases phosphorylation
protein 17003101
D019311 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Staurosporine inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of MAPK1 protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 15177934
D019311 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Staurosporine promotes the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of MAPK1 protein] increases activity
/ increases localization
/ increases phosphorylation
/ increases reaction
protein 15542774
D019311 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of MAPK3 protein]] decreases reaction
/ increases activity
/ increases localization
/ increases phosphorylation
protein 15542774
D019311 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Staurosporine inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases phosphorylation
protein 16251475
D019311 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Staurosporine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases phosphorylation
protein 19699794
D019311 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Staurosporine inhibits the reaction [Nicotine results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases phosphorylation
protein 17003101
D019311 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Staurosporine inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 15177934
D019311 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Staurosporine promotes the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of MAPK3 protein] increases activity
/ increases localization
/ increases phosphorylation
/ increases reaction
protein 15542774
D019311 4137 MAPT
DDPAC
FTDP-17
MAPTL
MSTD
MTBT1
MTBT2
PPND
TAU
microtubule-associated protein tau Staurosporine inhibits the reaction [oxophenylarsine results in increased phosphorylation of MAPT protein] decreases reaction
/ increases phosphorylation
protein 10737602
D019311 4139 MARK1
MARK
Par-1c
Par1c
MAP/microtubule affinity-regulating kinase 1 (EC:2.7.11.1 2.7.11.26) Staurosporine inhibits the reaction [oxophenylarsine results in increased activity of MARK1 protein] decreases reaction
/ increases activity
protein 10737602
D019311 4170 MCL1
BCL2L3
EAT
MCL1-ES
MCL1L
MCL1S
Mcl-1
TM
bcl2-L-3
mcl1/EAT
myeloid cell leukemia sequence 1 (BCL2-related) MCL1 results in decreased susceptibility to Staurosporine decreases response to substance
15217956
D019311 4170 MCL1
BCL2L3
EAT
MCL1-ES
MCL1L
MCL1S
Mcl-1
TM
bcl2-L-3
mcl1/EAT
myeloid cell leukemia sequence 1 (BCL2-related) Staurosporine results in increased cleavage of MCL1 protein increases cleavage
protein 16007152
D019311 4193 MDM2
ACTFS
HDMX
hdm2
MDM2 oncogene, E3 ubiquitin protein ligase Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]]] affects binding
/ decreases reaction
protein 15542774
D019311 4318 MMP9
CLG4B
GELB
MANDP2
MMP-9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) Staurosporine inhibits the reaction [Homocysteine results in increased activity of MMP9 protein] decreases reaction
/ increases activity
protein 16251475
D019311 4318 MMP9
CLG4B
GELB
MANDP2
MMP-9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) Staurosporine inhibits the reaction [Homocysteine results in increased expression of MMP9 protein] decreases reaction
/ increases expression
protein 16251475
D019311 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog MYC protein inhibits the reaction [Staurosporine results in increased abundance of Reactive Oxygen Species] decreases reaction
/ increases abundance
protein 17628013
D019311 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog MYC protein results in decreased susceptibility to Staurosporine decreases response to substance
protein 17628013
D019311 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog Staurosporine promotes the reaction [MYC protein binds to GCLC promoter] affects binding
/ increases reaction
protein 17628013
D019311 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog Staurosporine promotes the reaction [MYC protein binds to GCLM promoter] affects binding
/ increases reaction
protein 17628013
D019311 4922 NTS
NMN-125
NN
NT
NT/N
NTS1
neurotensin Staurosporine inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of AKT1 protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 15177934
D019311 4922 NTS
NMN-125
NN
NT
NT/N
NTS1
neurotensin Staurosporine inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 15177934
D019311 4922 NTS
NMN-125
NN
NT
NT/N
NTS1
neurotensin Staurosporine inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of MAPK1 protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 15177934
D019311 4922 NTS
NMN-125
NN
NT
NT/N
NTS1
neurotensin Staurosporine inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 15177934
D019311 142 PARP1
ADPRT
ADPRT_1
ADPRT1
ARTD1
PARP
PARP-1
PPOL
pADPRT-1
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) Staurosporine results in increased cleavage of PARP1 protein increases cleavage
protein 18451153
21447800
D019311 5530 PPP3CA
CALN
CALNA
CALNA1
CCN1
CNA1
PPP2B
protein phosphatase 3, catalytic subunit, alpha isozyme (EC:3.1.3.16) Staurosporine results in increased cleavage of PPP3CA protein increases cleavage
protein 10898953
D019311 5578 PRKCA
AAG6
PKC-alpha
PKCA
PRKACA
protein kinase C, alpha (EC:2.7.11.13) Staurosporine affects the localization of and affects the activity of PRKCA protein affects activity
/ affects localization
protein 16225760
D019311 5580 PRKCD
MAY1
PKCD
nPKC-delta
protein kinase C, delta (EC:2.7.10.2 2.7.11.13) Staurosporine inhibits the reaction [Curcumin results in increased phosphorylation of PRKCD protein] decreases reaction
/ increases phosphorylation
protein 17171638
D019311 5664 PSEN2
AD3L
AD4
CMD1V
PS2
STM2
presenilin 2 (Alzheimer disease 4) pifithrin inhibits the reaction [PSEN2 protein mutant form promotes the reaction [Staurosporine results in increased activity of CASP3 protein]] decreases reaction
/ increases activity
/ increases reaction
protein 12556443
D019311 5664 PSEN2
AD3L
AD4
CMD1V
PS2
STM2
presenilin 2 (Alzheimer disease 4) PSEN2 protein mutant form promotes the reaction [Staurosporine results in increased activity of CASP3 protein] increases activity
/ increases reaction
protein 12556443
D019311 5664 PSEN2
AD3L
AD4
CMD1V
PS2
STM2
presenilin 2 (Alzheimer disease 4) Staurosporine promotes the reaction [PSEN2 protein mutant form results in increased expression of APP protein] increases expression
/ increases reaction
protein 12556443
D019311 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Staurosporine inhibits the reaction [Nicotine results in increased expression of PTGS2] decreases reaction
/ increases expression
17003101
D019311 57468 SLC12A5
KCC2
solute carrier family 12 (potassium/chloride transporter), member 5 Staurosporine inhibits the reaction [SLC12A5 protein results in increased import of Thallium] decreases reaction
/ increases import
protein 20086212
D019311 57468 SLC12A5
KCC2
solute carrier family 12 (potassium/chloride transporter), member 5 Staurosporine results in increased activity of SLC12A5 protein increases activity
protein 20086212
D019311 114571 SLC22A9
HOAT4
OAT4
OAT7
UST3H
ust3
solute carrier family 22 (organic anion transporter), member 9 Staurosporine inhibits the reaction [Phorbol 12,13-Dibutyrate affects the localization of SLC22A9 protein] affects localization
/ decreases reaction
protein 17341544
D019311 114571 SLC22A9
HOAT4
OAT4
OAT7
UST3H
ust3
solute carrier family 22 (organic anion transporter), member 9 Staurosporine inhibits the reaction [Phorbol 12,13-Dibutyrate results in decreased activity of SLC22A9 protein] decreases activity
/ decreases reaction
protein 17341544
D019311 8884 SLC5A6
SMVT
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 Staurosporine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin] decreases reaction
/ increases transport
protein 15561972
D019311 6622 SNCA
NACP
PARK1
PARK4
PD1
synuclein, alpha (non A4 component of amyloid precursor) [Staurosporine co-treated with Rotenone] promotes the reaction [SNCA protein binds to SNCA protein] affects binding
/ affects cotreatment
/ increases reaction
protein 19114014
D019311 6774 STAT3
APRF
HIES
signal transducer and activator of transcription 3 (acute-phase response factor) Staurosporine inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] decreases reaction
/ increases phosphorylation
protein 18448488
D019311 10492 SYNCRIP
GRY-RBP
GRYRBP
HNRNPQ
HNRPQ1
NSAP1
PP68
hnRNP-Q
synaptotagmin binding, cytoplasmic RNA interacting protein Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of SYNCRIP protein] affects localization
/ decreases reaction
protein 19331829
D019311 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]]] affects binding
/ decreases reaction
protein 15542774
D019311 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein]] decreases reaction
/ increases activity
/ increases localization
/ increases phosphorylation
protein 15542774
D019311 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Staurosporine promotes the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein] increases activity
/ increases localization
/ increases phosphorylation
/ increases reaction
protein 15542774
D019311 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor Staurosporine results in increased cleavage of VDR protein increases cleavage
protein 18832097
D019311 7422 VEGFA
MVCD1
VEGF
VPF
vascular endothelial growth factor A Staurosporine inhibits the reaction [VEGFA protein results in increased abundance of phosphatidylbutanol] decreases reaction
/ increases abundance
protein 14704231
D019311 7422 VEGFA
MVCD1
VEGF
VPF
vascular endothelial growth factor A Staurosporine inhibits the reaction [VEGFA protein results in increased expression of HMOX1 protein] decreases reaction
/ increases expression
protein 12788823
D019311 7490 WT1
AWT1
EWS-WT1
GUD
NPHS4
WAGR
WIT-2
WT33
Wilms tumor 1 Staurosporine results in increased expression of WT1 protein increases expression
protein 12914969

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (200)

OMIM preferred title UniProt
#613762 46,xy sex reversal 6; srxy6 Q13233
#100800 Achondroplasia; ach P22607
#615224 Advanced sleep phase syndrome, familial, 2; fasps2 P48730
#300755 Agammaglobulinemia, x-linked; xla Q06187
#207410 Antley-bixler syndrome without genital anomalies or disordered steroidogenesis; abs2 P21802
#613780 Aortic aneurysm, familial thoracic 7; aat7 Q15746
#101200 Apert syndrome P21802
#609135 Aplastic anemia O14746
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#611064 Asthma-related traits, susceptibility to, 5 Q9Y616
#615007 Basal ganglia calcification, idiopathic, 4; ibgc4 P09619
#123790 Beare-stevenson cutis gyrata syndrome; bstvs P21802
#614592 Bent bone dysplasia syndrome; bbds P21802
#109800 Bladder cancer P22607
#112600 Brachydactyly, type a2; bda2 O00238
#114480 Breast cancer O96017
P31749
P42336
#600880 Budd-chiari syndrome; bdchs O60674
#610474 Camptodactyly, tall stature, and hearing loss syndrome P22607
#115150 Cardiofaciocutaneous syndrome 1; cfc1 P15056
#615279 Cardiofaciocutaneous syndrome 3; cfc3 Q02750
#615280 Cardiofaciocutaneous syndrome 4; cfc4 P36507
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#192600 Cardiomyopathy, familial hypertrophic, 1; cmh1 Q9H1R3
#600858 Cardiomyopathy, familial hypertrophic, 6; cmh6 Q9UGJ0
#116600 Cataract 6, multiple types; ctrct6 P29317
#209880 Central hypoventilation syndrome, congenital; cchs P07949
#603956 Cervical cancer P22607
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#613641 Charcot-marie-tooth disease, recessive intermediate b; cmtrib Q15046
#609441 Chondrodysplasia, acromesomelic, with genital anomalies O00238
#612242 Chromosome 10q23 deletion syndrome P36894
#613630 Cocoon syndrome O15111
#612016 Coenzyme q10 deficiency, primary, 4; coq10d4 Q8NI60
#303600 Coffin-lowry syndrome; cls P51812
#614331 Colorectal cancer, hereditary nonpolyposis, type 6; hnpcc6 P37173
#114500 Colorectal cancer; crc P07949
P15056
P29320
P31749
P42336
#612918 Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi P42336
#615108 Cowden syndrome 5; cws5 P42336
#615109 Cowden syndrome 6; cws6 P31749
#123500 Crouzon syndrome P21802
#612247 Crouzon syndrome with acanthosis nigricans; can P22607
#607101 Deafness, autosomal recessive 30; dfnb30 Q8NEV4
#613916 Deafness, autosomal recessive 89; dfnb89 Q15046
#610549 Diabetes mellitus, insulin-resistant, with acanthosis nigricans P06213
#125853 Diabetes mellitus, noninsulin-dependent; niddm P06213
P31751
#119900 Digital clubbing, isolated congenital P15428
#246200 Donohue syndrome P06213
#613989 Dyskeratosis congenita, autosomal dominant, 2; dkca2 O14746
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#612651 Endocrine-cerebroosteodysplasia; eco Q9UPZ9
#300672 Epileptic encephalopathy, early infantile, 2; eiee2 O76039
#133239 Esophageal cancer P37173
#300422 Fg syndrome 4; fgs4 O14936
#135100 Fibrodysplasia ossificans progressiva; fop Q04771
#600274 Frontotemporal dementia; ftd P10636
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#606764 Gastrointestinal stromal tumor; gist P10721
P16234
#177700 Glaucoma 1, open angle, p; glc1p Q9UHD2
#137800 Glioma susceptibility 1; glm1 P04626
#306000 Glycogen storage disease ixa1; gsd9a1 P46019
#261750 Glycogen storage disease ixb; gsd9b Q93100
#613027 Glycogen storage disease ixc; gsd9c P15735
#261740 Glycogen storage disease of heart, lethal congenital Q9UGJ0
#300559 Glycogen storage disease, type ixd; gsd9d P46020
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#602089 Hemangioma, capillary infantile P35916
P35968
#114550 Hepatocellular carcinoma P08581
P42336
#613751 Heterotaxy, visceral, 4, autosomal; htx4 Q13705
#142623 Hirschsprung disease, susceptibility to, 1; hscr1 P07949
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#607685 Hypereosinophilic syndrome, idiopathic; hes P16234
#602485 Hyperinsulinemic hypoglycemia, familial, 3; hhf3 P35557
#609968 Hyperinsulinemic hypoglycemia, familial, 5; hhf5 P06213
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#146000 Hypochondroplasia; hch P22607
#147950 Hypogonadotropic hypogonadism 2 with or without anosmia; hh2 P11362
#240900 Hypoinsulinemic hypoglycemia with hemihypertrophy; hihghh P31751
#602014 Hypomagnesemia 1, intestinal; homg1 Q9BX84
#612244 Inflammatory bowel disease 13; ibd13 P08183
#256800 Insensitivity to pain, congenital, with anhidrosis; cipa P04629
#270450 Insulin-like growth factor i, resistance to P08069
#610799 Invasive pneumococcal disease, recurrent isolated, 1; ipd1 Q9NWZ3
#607676 Irak4 deficiency Q9NWZ3
#307200 Isolated growth hormone deficiency, type iii; ighd3 Q06187
#123150 Jackson-weiss syndrome; jws P21802
#607785 Juvenile myelomonocytic leukemia; jmml P09619
#174900 Juvenile polyposis syndrome; jps P36894
#182000 Keratosis, seborrheic P22607
P42336
#149730 Lacrimoauriculodentodigital syndrome; ladd P21802
P22607
#611554 Leopard syndrome 2 P04049
#613707 Leopard syndrome 3 P15056
#607598 Lethal congenital contracture syndrome 2; lccs2 P21860
#611369 Lethal congenital contracture syndrome 3; lccs3 O60331
#601626 Leukemia, acute myeloid; aml O60674
P09619
P10721
P36888
#608232 Leukemia, chronic myeloid; cml P00519
#221820 Leukoencephalopathy, diffuse hereditary, with spheroids; hdls P07333
#609265 Li-fraumeni syndrome 2; lfs2 O96017
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#609192 Loeys-dietz syndrome, type 1a; lds1a P36897
#610168 Loeys-dietz syndrome, type 1b; lds1b P37173
#608967 Loeys-dietz syndrome, type 2a; lds2a P36897
#610380 Loeys-dietz syndrome, type 2b; lds2b P37173
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P15056
#153100 Lymphedema, hereditary, ia P35916
#605027 Lymphoma, non-hodgkin, familial P15056
#613011 Lymphoproliferative syndrome 1; lpfs1 Q08881
#612371 Major affective disorder 7; mafd7 P17861
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613375 Maturity-onset diabetes of the young, type 11; mody11 P51451
#125851 Maturity-onset diabetes of the young, type 2; mody2 P35557
#606391 Maturity-onset diabetes of the young; mody P35557
#602501 Megalencephaly-capillary malformation-polymicrogyria syndrome; mcap P42336
#603387 Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome; mpph P42336
Q9Y243
#609048 Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 P11802
#615134 Melanoma, cutaneous malignant, susceptibility to, 9; cmm9 O14746
#300749 Mental retardation and microcephaly with pontine and cerebellar hypoplasia; micpch O14936
#614104 Mental retardation, autosomal dominant 7; mrd7 Q13627
#300844 Mental retardation, x-linked 19; mrx19 P51812
#300558 Mental retardation, x-linked 30; mrx30 O75914
#602849 Muenke syndrome; mnkes P22607
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#171400 Multiple endocrine neoplasia, type iia; men2a P07949
#162300 Multiple endocrine neoplasia, type iib; men2b P07949
#132800 Multiple self-healing squamous epithelioma, susceptibility to; msse P36897
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#608931 Myasthenic syndrome, congenital, associated with acetylcholine receptor deficiency O15146
#254450 Myelofibrosis O60674
#254500 Myeloma, multiple P22607
P24385
#131440 Myeloproliferative disorder, chronic, with eosinophilia P09619
#228550 Myofibromatosis, infantile, 1; imf1 P09619
#160900 Myotonic dystrophy 1; dm1 Q09013
#613014 Neuroblastoma, susceptibility to, 3; nblst3 Q9UM73
#162900 Nevus, epidermal P22607
#257220 Niemann-pick disease, type c1; npc1 O15118
#611553 Noonan syndrome 5; ns5 P04049
#613706 Noonan syndrome 7; ns7 P15056
#613886 Obesity, hyperphagia, and developmental delay Q16620
#613411 Oguchi disease 2 Q15835
#259500 Osteogenic sarcoma O96017
#166250 Osteoglophonic dysplasia; ogd P11362
#167000 Ovarian cancer P04626
P42336
#607060 Parkinson disease 8, autosomal dominant; park8 Q5S007
#168600 Parkinson disease, late-onset; pd Q5S007
#260540 Parkinson-dementia syndrome P10636
#175200 Peutz-jeghers syndrome; pjs Q15831
#101600 Pfeiffer syndrome P11362
P21802
#171300 Pheochromocytoma P07949
#172700 Pick disease of brain P10636
#172800 Piebald trait; pbt P10721
#262190 Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities P06213
#263300 Polycythemia vera; pv O60674
#610069 Polyposis syndrome, hereditary mixed, 2; hmps2 P36894
#263650 Popliteal pterygium syndrome, lethal type P57078
#176807 Prostate cancer O96017
P29323
#603688 Prostate cancer/brain cancer susceptibility P29323
#176920 Proteus syndrome P31749
#614742 Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1; pfbmft1 O14746
#178500 Pulmonary fibrosis, idiopathic; ipf O14746
#178600 Pulmonary hypertension, primary, 1; pph1 Q13873
#265450 Pulmonary venoocclusive disease 1, autosomal dominant; pvod1 Q13873
#191830 Renal adysplasia P07949
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#275210 Restrictive dermopathy, lethal P02545
#613862 Retinitis pigmentosa 38; rp38 Q12866
#614181 Retinitis pigmentosa 62; rp62 P20794
#609579 Scaphocephaly, maxillary retrusion, and mental retardation P21802
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#269840 Selective t-cell defect; stcd P43403
#600802 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-negative P52333
#609620 Short qt syndrome 1; sqt1 Q12809
#263520 Short-rib thoracic dysplasia 6 with or without polydactyly; srtd6 Q96PY6
#243060 Spermatogenic failure 5; spgf5 Q9UQB9
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#605361 Spinocerebellar ataxia 14; sca14 P05129
#271665 Spondylometaepiphyseal dysplasia, short limb-hand type Q16832
%612223 Stature quantitative trait locus 11; stqtl11 Q00534
#601367 Stroke, ischemic P24723
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#614868 T-cell immunodeficiency, recurrent infections, and autoimmunity with or without cardiac malformations; tiiac Q13043
#600376 Telangiectasia, hereditary hemorrhagic, type 2; hht2 P37023
#273300 Testicular germ cell tumor; tgct O94804
P10721
P22607
Q15831
#187600 Thanatophoric dysplasia, type i; td1 P22607
#187601 Thanatophoric dysplasia, type ii; td2 P22607
#614521 Thrombocythemia 3; thcyt3 O60674
#155240 Thyroid carcinoma, familial medullary; mtc P07949
#188550 Thyroid carcinoma, papillary P04629
P07949
#190440 Trigonocephaly 1; trigno1 P11362
#611521 Tyrosine kinase 2 deficiency P29597
#600195 Venous malformations, multiple cutaneous and mucosal; vmcm Q02763
#194200 Wolff-parkinson-white syndrome Q9UGJ0

KEGG DISEASE (129)

KEGG disease name UniProt
H00468 Acromesomelic dysplasia with genital anomalies O00238 (related)
H00482 Brachydactyly O00238 (related)
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00764 Cri du chat syndrome O14746 (related)
H01132 Aplastic anemia (AA) O14746 (related)
H01299 Idiopathic pulmonary fibrosis O14746 (related)
H00022 Bladder cancer O14746 (marker)
P00533 (related)
P04626 (related)
P22607 (related)
P53355 (related)
H00024 Prostate cancer O14746 (marker)
H00577 Syndromic X-linked mental retardation with epilepsy or seizures O14936 (related)
H00894 FG syndrome (FGS) O14936 (related)
H00882 Cocoon syndrome O15111 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00770 Congenital myasthenic syndrome O15146 (related)
H00865 Lethal congenital contractural syndrome (LCCS) O60331 (related)
P21860 (related)
H00012 Polycythemia vera O60674 (related)
O60674 (marker)
H00480 Non-syndromic X-linked mental retardation O75914 (related)
P51812 (related)
H00478 Prader-Willi and Angelman syndromes O76039 (related)
H00606 Early infantile epileptic encephalopathy O76039 (related)
P53779 (related)
H00881 Li-Fraumeni syndrome O96017 (related)
H00018 Gastric cancer O96020 (related)
P00533 (related)
P04626 (related)
P08581 (related)
P21802 (related)
P24864 (related)
H00055 Laryngeal cancer O96020 (related)
P00533 (related)
P00533 (marker)
P24385 (related)
P24385 (marker)
P24864 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) P00519 (related)
P00519 (marker)
Q03164 (related)
Q03164 (marker)
H00004 Chronic myeloid leukemia (CML) P00519 (related)
P00519 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P24385 (related)
P24385 (marker)
H00017 Esophageal cancer P00533 (related)
P24385 (related)
H00028 Choriocarcinoma P00533 (related)
P04626 (related)
P07333 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
P11802 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P09619 (related)
P11802 (related)
P16234 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q15046 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P31751 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00019 Pancreatic cancer P04626 (related)
Q15831 (related)
H00026 Endometrial Cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
P31751 (related)
P42336 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P24385 (related)
H00046 Cholangiocarcinoma P04626 (related)
P08581 (related)
H00032 Thyroid cancer P04629 (related)
P07949 (related)
P07949 (marker)
P15056 (related)
H00043 Neuroblastoma P04629 (related)
P04629 (marker)
Q16288 (related)
Q16620 (related)
H00265 Hereditary sensory and autonomic neuropathy (HSAN) P04629 (related)
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
Q8NI60 (related)
H00719 Leprechaunism P06213 (related)
H00942 Rabson-Mendenhall syndrome P06213 (related)
H01228 Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) P06213 (related)
H01267 Familial hyperinsulinemic hypoglycemia (HHF) P06213 (related)
P35557 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
P43403 (related)
H00822 Renal agenesis and Renal adysplasia P07949 (related)
H00910 Hirschsprung disease (HD) P07949 (related)
H00916 Congenital central hypoventilation syndrome (CCHS) P07949 (related)
H00015 Malignant pleural mesothelioma P08069 (related)
H00050 Synovial sarcoma P08069 (related)
H01274 Growth delay due to insulin-like growth factor I resistance P08069 (related)
H00021 Renal cell carcinoma P08581 (related)
H00014 Non-small cell lung cancer P08922 (related)
Q9UM73 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00003 Acute myeloid leukemia (AML) P10721 (related)
P10721 (marker)
P36888 (related)
H00170 Piebaldism P10721 (related)
H00023 Testicular cancer P10721 (marker)
H00255 Hypogonadotropic hypogonadism P11362 (related)
H00443 Osteoglophonic dysplasia (OD) P11362 (related)
H00458 Craniosynostosis P11362 (related)
P21802 (related)
P22607 (related)
H00516 Isolated orofacial clefts P11362 (related)
H01207 Trigonocephaly P11362 (related)
H00038 Malignant melanoma P11802 (related)
P15056 (related)
H00523 Noonan syndrome and related disorders P15056 (related)
P36507 (related)
Q02750 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00069 Glycogen storage diseases (GSD) P15735 (related)
P46019 (related)
P46020 (related)
Q93100 (related)
Q9UGJ0 (related)
H00642 Lacrimo-auriculo-dento-digital syndrome (LADD) P21802 (related)
P22607 (related)
H00408 Type I diabetes mellitus P21860 (related)
Q04759 (related)
H00010 Multiple myeloma P22607 (related)
P24385 (related)
P30281 (related)
H00505 FGFR3-related short limb skeletal dysplasias P22607 (related)
H00997 CATSHL syndrome P22607 (related)
H00006 Hairy-cell leukemia P24385 (related)
H00559 von Hippel-Lindau syndrome P24385 (related)
H00047 Gallbladder cancer P24385 (marker)
H01202 Cataract P29317 (related)
H00107 Other well-defined immunodeficiency syndromes P29597 (related)
Q08881 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H00410 Maturity onset diabetes of the young (MODY) P35557 (related)
P51451 (related)
H00512 Permanent neonatal diabetes mellitus (PNDM) P35557 (related)
H00535 Lymphedemas P35916 (related)
H01023 Juvenile polyposis syndrome P36894 (related)
H01024 Hereditary mixed polyposis syndrome P36894 (related)
H00800 Loeys-Dietz syndrome (LDS) P36897 (related)
P37173 (related)
H00801 Familial thoracic aortic aneurysm and dissection (TAAD) P36897 (related)
P37173 (related)
Q15746 (related)
H00533 Hereditary hemorrhagic telangiectasia (HHT) P37023 (related)
H00020 Colorectal cancer P37173 (related)
H00005 Chronic lymphocytic leukemia (CLL) P43403 (marker)
H00574 Coffin-Lowry syndrome (CLS) P51812 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P52333 (related)
H00531 Venous malformations Q02763 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00430 Fibrodysplasia ossificans progressiva (FOP) Q04771 (related)
Q04771 (marker)
H00085 Agammaglobulinemias Q06187 (related)
H00254 Pituitary Dwarfism (PD) Q06187 (related)
H00568 Myotonic dystrophy (DM) Q09013 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00527 Retinitis pigmentosa (RP) Q12866 (related)
H00632 Heterotaxy Q13705 (related)
H01300 Primary pulmonary hypertension (PPH) Q13873 (related)
H00666 Peutz-Jeghers syndrome Q15831 (related)
H00787 Congenital stationary night blindness (CSNB) Q15835 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)
H00777 Spondylometaepiphyseal dysplasia, short limb-hand type Q16832 (related)
H00057 Parkinson's disease (PD) Q5S007 (related)
H00066 Lewy body dementia (LBD) Q5S007 (related)
H00605 Deafness, autosomal recessive Q8NEV4 (related)
H00999 Coenzyme Q10 deficiency Q8NI60 (related)
H00511 Short rib-polydactyly syndrome Q96PY6 (related)
H01210 Hypomagnesemia Q9BX84 (related)
H00096 Defects of toll-like receptor signaling Q9NWZ3 (related)
H00292 Hypertrophic cardiomyopathy (HCM) Q9UGJ0 (related)
H01154 Wolff-Parkinson-White (WPW) syndrome Q9UGJ0 (related)
H00972 Endocrine-cerebro-osteodysplasia syndrome Q9UPZ9 (related)
H01282 Spermatogenic failure Q9UQB9 (related)

Diseases related to CTD interactions

1 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D004487 D019311 Edema therapeutic
8273558