KNApSAcK Metabolite C00018319
Metabolite
KNApSAcK Entry
| id | C00018319 |
|---|---|
| Name | Myxothiazol / Myxothiazole A |
| CAS RN | 76706-55-3 |
| Standard InChI | InChI=1S/C25H33N3O3S2/c1-16(2)9-7-8-10-17(3)24-28-20(15-33-24)25-27-19(14-32-25)11-12-21(30-5)18(4)22(31-6)13-23(26)29/h7-18,21H,1-6H3,(H2,26,29)/b9-7+,10-8+,12-11+,22-13+/t17-,18+,21-/m0/s1 |
| Standard InChI (Main Layer) | InChI=1S/C25H33N3O3S2/c1-16(2)9-7-8-10-17(3)24-28-20(15-33-24)25-27-19(14-32-25)11-12-21(30-5)18(4)22(31-6)13-23(26)29/h7-18,21H,1-6H3,(H2,26,29) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 4167 |
Link
ChEMBL
| By standard InChI | CHEMBL454568 |
|---|---|
| By standard InChI Main Layer | CHEMBL454568 CHEMBL605952 |
KEGG
| By LinkDB | C15674 |
|---|
CTD
| By CAS RN | C030517 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Myxococcaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Myxococcus fulvus strain Mx f16 | 32 | Myxococcaceae | Bacteria |
Human Protein / Gene in interaction
CTD interaction (5)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C030517 | 948 |
CD36
BDPLT10 CHDS7 FAT GP3B GP4 GPIV PASIV SCARB3 |
CD36 molecule (thrombospondin receptor) | myxothiazol inhibits the reaction [[Oxygen deficiency results in increased abundance of Reactive Oxygen Species] which results in increased expression of CD36 mRNA] |
decreases reaction
/ increases abundance / increases expression |
mRNA |
19640849
|
| C030517 | 10725 |
NFAT5
NF-AT5 NFATL1 NFATZ OREBP TONEBP |
nuclear factor of activated T-cells 5, tonicity-responsive | myxothiazol inhibits the reaction [Sodium Chloride results in increased activity of NFAT5 protein] |
decreases reaction
/ increases activity |
protein |
16303854
|
| C030517 | 6539 |
SLC6A12
BGT-1 BGT1 GAT2 |
solute carrier family 6 (neurotransmitter transporter), member 12 | myxothiazol inhibits the reaction [Sodium Chloride results in increased expression of SLC6A12 mRNA] |
decreases reaction
/ increases expression |
mRNA |
16303854
|
| C030517 | 6648 |
SOD2
IPOB MNSOD MVCD6 |
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) | myxothiazol inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11264281
|
| C030517 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | myxothiazol inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA] |
decreases reaction
/ increases expression |
protein |
11264281
|