Metabolite

KNApSAcK Entry

id C00019635
Name GMP / Guanosine 5'-phosphate
CAS RN 85-32-5
Standard InChI InChI=1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
Standard InChI (Main Layer) InChI=1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)

Cluster

Phytochemical cluster No. 12
KCF-S cluster No. 2692

Link

ChEMBL

By standard InChI CHEMBL283807
By standard InChI Main Layer CHEMBL283807 CHEMBL1242996 CHEMBL2364560

KEGG

By LinkDB C00144

CTD

By CAS RN D006157

Species

Summary

Plant class

class name count

Family

family name count
Enterobacteriaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Escherichia coli 562 Enterobacteriaceae Bacteria

Human Protein / Gene in interaction

4 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q16774 Guanylate kinase Enzyme CHEMBL283807 CHEMBL1242996 CHEMBL686065 (1) CHEMBL686067 (1)
CHEMBL686069 (1)
0 / 0
Q9BZX2 Uridine-cytidine kinase 2 Enzyme CHEMBL1242996 CHEMBL2364560 CHEMBL752080 (2) CHEMBL752081 (2)
CHEMBL752085 (2) CHEMBL752087 (2)
CHEMBL752090 (2) CHEMBL752091 (2)
0 / 0
P12268 Inosine-5'-monophosphate dehydrogenase 2 Oxidoreductase CHEMBL1242996 CHEMBL697164 (1)
0 / 0
P20839 Inosine-5'-monophosphate dehydrogenase 1 Oxidoreductase CHEMBL1242996 CHEMBL697164 (1)
2 / 2

CTD interaction (1)

compound gene gene name gene description interaction interaction type form reference
pmid
D006157 2530 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase) (EC:2.4.1.68) Guanosine Monophosphate results in decreased activity of FUT8 protein decreases activity
protein 12770769

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#613837 Leber congenital amaurosis 11; lca11 P20839
#180105 Retinitis pigmentosa 10; rp10 P20839

KEGG DISEASE (2)

KEGG disease name UniProt
H00527 Retinitis pigmentosa (RP) P20839 (related)
H00837 Leber congenital amaurosis (LCR) P20839 (related)