PCIDB

KNApSAcK Metabolite C00021388

Metabolite

KNApSAcK Entry

id C00021388
Name Teferin
CAS RN 54526-95-3
Standard InChI InChI=1S/C23H32O5/c1-14(2)23(26)11-10-22(4)9-8-15(3)12-19(20(22)23)28-21(25)16-6-7-17(24)18(13-16)27-5/h6-8,13-14,19-20,24,26H,9-12H2,1-5H3/t19-,20+,22-,23+/m0/s1
Standard InChI (Main Layer) InChI=1S/C23H32O5/c1-14(2)23(26)11-10-22(4)9-8-15(3)12-19(20(22)23)28-21(25)16-6-7-17(24)18(13-16)27-5/h6-8,13-14,19-20,24,26H,9-12H2,1-5H3

Cluster

Phytochemical cluster
KCF-S cluster No. 327

Link

ChEMBL

By standard InChI CHEMBL464467
By standard InChI Main Layer CHEMBL464467 CHEMBL1552750 CHEMBL1967912

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
asterids 1

Family

family name count
Apiaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Ferula tenuisecta 82087 Apiaceae asterids Viridiplantae

Human Protein / Gene in interaction

9 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL1552750 CHEMBL1614110 (1)
1 / 0
Q99700 Ataxin-2 Unclassified protein CHEMBL464467 CHEMBL2114784 (1)
1 / 1
P37840 Alpha-synuclein Unclassified protein CHEMBL464467 CHEMBL2354282 (1)
4 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL1552750 CHEMBL1614027 (1)
0 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL464467 CHEMBL1794584 (1)
2 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL464467 CHEMBL2114788 (1)
0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL1552750 CHEMBL1614227 (1)
3 / 3
P03372 Estrogen receptor NR3A1 CHEMBL464467 CHEMBL1004750 (1)
1 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL1552750 CHEMBL1613777 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#114500 Colorectal cancer; crc P84022
#127750 Dementia, lewy body; dlb P37840
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (9)

KEGG disease name UniProt
H00026 Endometrial Cancer P03372 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)