PCIDB

KNApSAcK Metabolite C00002427

Metabolite

KNApSAcK Entry

id C00002427
Name Eupatoriochromene / Desmethylencecalin
CAS RN 19013-03-7
Standard InChI InChI=1S/C13H14O3/c1-8(14)10-6-9-4-5-13(2,3)16-12(9)7-11(10)15/h4-7,15H,1-3H3
Standard InChI (Main Layer) InChI=1S/C13H14O3/c1-8(14)10-6-9-4-5-13(2,3)16-12(9)7-11(10)15/h4-7,15H,1-3H3

Cluster

Phytochemical cluster
KCF-S cluster No. 1756

Link

ChEMBL

By standard InChI CHEMBL443462
By standard InChI Main Layer CHEMBL443462

KEGG

By LinkDB C09006

CTD

By CAS RN

Human Protein / Gene in interaction

5 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P04062 Glucosylceramidase Enzyme CHEMBL443462 CHEMBL1613818 (1)
6 / 4
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL443462 CHEMBL1614458 (1)
0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL443462 CHEMBL1614038 (1)
2 / 2
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL443462 CHEMBL1614108 (1) CHEMBL1613886 (1)
0 / 1
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL443462 CHEMBL1614364 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#119900 Digital clubbing, isolated congenital P15428
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#168600 Parkinson disease, late-onset; pd P04062
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8

KEGG DISEASE (8)

KEGG disease name UniProt
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00036 Osteosarcoma P08684 (marker)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)