PCIDB

KNApSAcK Metabolite C00002459

Metabolite

KNApSAcK Entry

id C00002459
Name Columbianetin
CAS RN 52842-47-4
Standard InChI InChI=1S/C14H14O4/c1-14(2,16)11-7-9-10(17-11)5-3-8-4-6-12(15)18-13(8)9/h3-6,11,16H,7H2,1-2H3/t11-/m1/s1
Standard InChI (Main Layer) InChI=1S/C14H14O4/c1-14(2,16)11-7-9-10(17-11)5-3-8-4-6-12(15)18-13(8)9/h3-6,11,16H,7H2,1-2H3

Cluster

Phytochemical cluster No. 25
KCF-S cluster No. 1336

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL201152

KEGG

By LinkDB C09210

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Rutaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Zanthoxylum americanum 354526 Rutaceae rosids Viridiplantae

Human Protein / Gene in interaction

7 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10253 Lysosomal alpha-glucosidase Hydrolase CHEMBL201152 CHEMBL1614103 (1) CHEMBL1614031 (1)
1 / 1
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL201152 CHEMBL1614458 (1)
0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme CHEMBL201152 CHEMBL1794495 (1)
2 / 2
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL201152 CHEMBL2114810 (1)
7 / 3
P56817 Beta-secretase 1 A1A CHEMBL201152 CHEMBL1936881 (1) CHEMBL1936882 (1)
0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL201152 CHEMBL1614038 (1)
2 / 2
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL201152 CHEMBL1613914 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#119900 Digital clubbing, isolated congenital P15428
#232300 Glycogen storage disease ii P10253
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#174800 Mccune-albright syndrome; mas P63092
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092

KEGG DISEASE (8)

KEGG disease name UniProt
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)