PCIDB

KNApSAcK Metabolite C00024784

Metabolite

KNApSAcK Entry

id C00024784
Name NSC 407281 / Tanacetone / Chrysanthone
CAS RN 1125-12-8
Standard InChI InChI=1S/C10H16O/c1-6(2)10-4-8(10)7(3)9(11)5-10/h6-8H,4-5H2,1-3H3
Standard InChI (Main Layer) InChI=1S/C10H16O/c1-6(2)10-4-8(10)7(3)9(11)5-10/h6-8H,4-5H2,1-3H3

Cluster

Phytochemical cluster No. 35
KCF-S cluster No. 1161

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL1444078

KEGG

By LinkDB

CTD

By CAS RN C005790

Species

Summary

Plant class

class name count

Family

family name count
Didymellaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Ascochyta chrysanthemi 1200837 Didymellaceae Fungi

Human Protein / Gene in interaction

2 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P16473 Thyrotropin receptor Glycohormone receptor CHEMBL1444078 CHEMBL1614281 (1) CHEMBL1614361 (1)
3 / 2
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL1444078 CHEMBL1794401 (1)
0 / 0

CTD interaction (3)

compound gene gene name gene description interaction interaction type form reference
pmid
C005790 2554 GABRA1
ECA4
EJM
EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1 beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 15588619
C005790 2561 GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2 beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 15588619
C005790 2566 GABRG2
CAE2
ECA2
GEFSP3
gamma-aminobutyric acid (GABA) A receptor, gamma 2 beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]] affects binding
/ decreases reaction
/ increases activity
protein 15588619

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473

KEGG DISEASE (2)

KEGG disease name UniProt
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)