Metabolite

KNApSAcK Entry

id C00002526
Name Prunetol / Genistein / Genisteol / Sophoricol / Differenol A / 1,3,7-Trihydroxyxanthone / 5,7,4'-Trihydroxyisoflavone
CAS RN 446-72-0
Standard InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H
Standard InChI (Main Layer) InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 71

Link

ChEMBL

By standard InChI CHEMBL44
By standard InChI Main Layer CHEMBL44

KEGG

By LinkDB C06563

CTD

By CAS RN D019833

Species

Summary


List (241)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Acacia adunca 204988 Fabaceae rosids Viridiplantae
Acacia baileyana 383632 Fabaceae rosids Viridiplantae
Acacia binervata 138512 Fabaceae rosids Viridiplantae
Acacia calamifolia 139006 Fabaceae rosids Viridiplantae
Acacia cardiophylla 383638 Fabaceae rosids Viridiplantae
Acacia chrysotricha 1174753 Fabaceae rosids Viridiplantae
Acacia clunies-rossiae 1174755 Fabaceae rosids Viridiplantae
Acacia concurrens 3808 Fabaceae rosids Viridiplantae
Acacia constablei 383640 Fabaceae rosids Viridiplantae
Acacia cultriformis 138515 Fabaceae rosids Viridiplantae
Acacia dealbata 205042 Fabaceae rosids Viridiplantae
Acacia deanei 205356 Fabaceae rosids Viridiplantae
Acacia decurrens 205044 Fabaceae rosids Viridiplantae
Acacia elata 138021 Fabaceae rosids Viridiplantae
Acacia falciformis 139008 Fabaceae rosids Viridiplantae
Acacia filicifolia 383643 Fabaceae rosids Viridiplantae
Acacia fimbriata 21010 Fabaceae rosids Viridiplantae
Acacia holosericea 1120455 Fabaceae rosids Viridiplantae
Acacia irrorata 383645 Fabaceae rosids Viridiplantae
Acacia kettlewelliae 3808 Fabaceae rosids Viridiplantae
Acacia lanigera 3808 Fabaceae rosids Viridiplantae
Acacia leucoclada 138518 Fabaceae rosids Viridiplantae
Acacia longifolia 139010 Fabaceae rosids Viridiplantae
Acacia mabellae 383647 Fabaceae rosids Viridiplantae
Acacia mearnsii 139012 Fabaceae rosids Viridiplantae
Acacia melanoxylon 138028 Fabaceae rosids Viridiplantae
Acacia mollifolia 383648 Fabaceae rosids Viridiplantae
Acacia neriifolia 205053 Fabaceae rosids Viridiplantae
Acacia obtusifolia 866003 Fabaceae rosids Viridiplantae
Acacia oshanesii 383653 Fabaceae rosids Viridiplantae
Acacia oswaldii 139013 Fabaceae rosids Viridiplantae
Acacia parramattensis 138037 Fabaceae rosids Viridiplantae
Acacia pycnantha 880440 Fabaceae rosids Viridiplantae
Acacia retinodes 1050817 Fabaceae rosids Viridiplantae
Acacia rigens 694556 Fabaceae rosids Viridiplantae
Acacia silvestris 205063 Fabaceae rosids Viridiplantae
Acacia terminalis 383657 Fabaceae rosids Viridiplantae
Acacia trachyphloia 383658 Fabaceae rosids Viridiplantae
Acacia verniciflua 1120475 Fabaceae rosids Viridiplantae
Acacia vestita 1120476 Fabaceae rosids Viridiplantae
Adenocarpus decorticans 175395 Fabaceae rosids Viridiplantae
Adenocarpus foliolosus 49789 Fabaceae rosids Viridiplantae
Amphicarpaea bracteata 45679 Fabaceae rosids Viridiplantae
Anaxagorea luzonensis A.GRAY 235716 Annonaceae Magnoliophyta Viridiplantae
Andira inermis 53825 Fabaceae rosids Viridiplantae
Apios americana 185702 Fabaceae rosids Viridiplantae
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae
Baptisia alba 313911 Fabaceae rosids Viridiplantae
Baptisia australis 149633 Fabaceae rosids Viridiplantae
Baptisia bracteata 313912 Fabaceae rosids Viridiplantae
Baptisia calycosa 49796 Fabaceae rosids Viridiplantae
Baptisia cinerea 313913 Fabaceae rosids Viridiplantae
Baptisia lanceolata 49796 Fabaceae rosids Viridiplantae
Baptisia lecontei 49796 Fabaceae rosids Viridiplantae
Baptisia megacarpa 49796 Fabaceae rosids Viridiplantae
Baptisia nuttalliana 49796 Fabaceae rosids Viridiplantae
Baptisia perfoliata 49796 Fabaceae rosids Viridiplantae
Baptisia tinctoria 49797 Fabaceae rosids Viridiplantae
Bowdichia nitida 595543 Fabaceae rosids Viridiplantae
Cajanus cajan 3821 Fabaceae rosids Viridiplantae
Cajanus scarabaeoides 669084 Fabaceae rosids Viridiplantae
Calicotome spinosa 194235 Fabaceae rosids Viridiplantae
Calicotome villosa 49799 Fabaceae rosids Viridiplantae
Calopogonium caeruleum 109163 Fabaceae rosids Viridiplantae
Camptosema rubicundum 510209 Fabaceae rosids Viridiplantae
Canavalia eurycarpa 3822 Fabaceae rosids Viridiplantae
Canavalia gladiata 3824 Fabaceae rosids Viridiplantae
Clitoria falcata 43365 Fabaceae rosids Viridiplantae
Clitoria ternatea 43366 Fabaceae rosids Viridiplantae
Crotalaria juncea 3829 Fabaceae rosids Viridiplantae
Cudrania cochinchinensis 194324 Moraceae rosids Viridiplantae
Cudrania cochinchinensis var. gerontogea 3495 Moraceae rosids Viridiplantae
Cytisus albus 3833 Fabaceae rosids Viridiplantae
Cytisus baeticus 176349 Fabaceae rosids Viridiplantae
Cytisus commutatus 194237 Fabaceae rosids Viridiplantae
Cytisus fontanesii 176336 Fabaceae rosids Viridiplantae
Cytisus proliferus 49805 Fabaceae rosids Viridiplantae
Cytisus ratisbonensis 3833 Fabaceae rosids Viridiplantae
Cytisus scoparius 3835 Fabaceae rosids Viridiplantae
Cytisus striatus 176342 Fabaceae rosids Viridiplantae
Derris scandens 1225699 Fabaceae rosids Viridiplantae
Desmodium gangeticum 670324 Fabaceae rosids Viridiplantae
Desmodium uncinatum 225101 Fabaceae rosids Viridiplantae
Dipogon lignosus 132441 Fabaceae rosids Viridiplantae
Dunbaria villosa 553673 Fabaceae rosids Viridiplantae
Echinosophora koreensis 228658 Fabaceae rosids Viridiplantae
Echinospartum horridum 238419 Fabaceae rosids Viridiplantae
Erinacea anthyllis 70292 Fabaceae rosids Viridiplantae
Eriosema glomeratum 109225 Fabaceae rosids Viridiplantae
Eriosema nutans 109225 Fabaceae rosids Viridiplantae
Eriosema psoraleoides 109226 Fabaceae rosids Viridiplantae
Erythrina burttii 3841 Fabaceae rosids Viridiplantae
Erythrina indica 3845 Fabaceae rosids Viridiplantae
Erythrina latissima 3844 Fabaceae rosids Viridiplantae
Euchresta formosana 256638 Fabaceae rosids Viridiplantae
Fagelia bituminosa
Ficus cordata 309266 Moraceae rosids Viridiplantae
Ficus nymphaeifolia 182120 Moraceae rosids Viridiplantae
Ficus septica 100573 Moraceae rosids Viridiplantae
Flemingia macrophylla 520843 Fabaceae rosids Viridiplantae
Flemingia philippinensis 634991 Fabaceae rosids Viridiplantae
Flemingia stricta 520842 Fabaceae rosids Viridiplantae
Flemingia strobilifera 634992 Fabaceae rosids Viridiplantae
Galactia jussiaeana 100145 Fabaceae rosids Viridiplantae
Genista acanthoclada 274560 Fabaceae rosids Viridiplantae
Genista albida 319658 Fabaceae rosids Viridiplantae
Genista anglica 176347 Fabaceae rosids Viridiplantae
Genista canariensis 49847 Fabaceae rosids Viridiplantae
Genista cupanii 238484 Fabaceae rosids Viridiplantae
Genista depressa 49818 Fabaceae rosids Viridiplantae
Genista ephedroides 123905 Fabaceae rosids Viridiplantae
Genista hispanica 238491 Fabaceae rosids Viridiplantae
Genista hystrix 238493 Fabaceae rosids Viridiplantae
Genista linifolia 175406 Fabaceae rosids Viridiplantae
Genista lobelii 49818 Fabaceae rosids Viridiplantae
Genista microphylla 175408 Fabaceae rosids Viridiplantae
Genista monspessulana 49848 Fabaceae rosids Viridiplantae
Genista morisii 49818 Fabaceae rosids Viridiplantae
Genista obtusiramea 238500 Fabaceae rosids Viridiplantae
Genista pulchella 274574 Fabaceae rosids Viridiplantae
Genista radiata 136799 Fabaceae rosids Viridiplantae
Genista sagittalis 49809 Fabaceae rosids Viridiplantae
Genista salzmannii 274575 Fabaceae rosids Viridiplantae
Genista scorpius 238509 Fabaceae rosids Viridiplantae
Genista sericea 238510 Fabaceae rosids Viridiplantae
Genista sessilifolia 147456 Fabaceae rosids Viridiplantae
Genista spartioides 123911 Fabaceae rosids Viridiplantae
Genista stenopetala 49851 Fabaceae rosids Viridiplantae
Genista subcapitata 49818 Fabaceae rosids Viridiplantae
Genista triacanthos 238516 Fabaceae rosids Viridiplantae
Genista tridens 238518 Fabaceae rosids Viridiplantae
Genista tridentata 49810 Fabaceae rosids Viridiplantae
Genista ulicina 49818 Fabaceae rosids Viridiplantae
Glycine canescens 48924 Fabaceae rosids Viridiplantae
Glycine clandestina 45687 Fabaceae rosids Viridiplantae
Glycine falcata 45690 Fabaceae rosids Viridiplantae
Glycine latifolia 45691 Fabaceae rosids Viridiplantae
Glycine tabacina 44016 Fabaceae rosids Viridiplantae
Glycine tomentella 44015 Fabaceae rosids Viridiplantae
Glycyrrhiza glabra 49827 Fabaceae rosids Viridiplantae
Glycyrrhiza uralensis 74613 Fabaceae rosids Viridiplantae
Halotydeus destructor
Hardenbergia violacea 53885 Fabaceae rosids Viridiplantae
Hypericum scabrum 1137022 Hypericaceae rosids Viridiplantae
Kennedia coccinea 556511 Fabaceae rosids Viridiplantae
Kennedia nigricans 556512 Fabaceae rosids Viridiplantae
Kennedia procurrens 76708 Fabaceae rosids Viridiplantae
Kennedia rubicunda 76709 Fabaceae rosids Viridiplantae
Lablab purpureus 35936 Fabaceae rosids Viridiplantae
Laburnum anagyroides 49828 Fabaceae rosids Viridiplantae
Lespedeza cyrtobotrya 701533 Fabaceae rosids Viridiplantae
Lespedeza juncea 688283 Fabaceae rosids Viridiplantae
Lupinus arboreus 3872 Fabaceae rosids Viridiplantae
Lupinus arcticus 53215 Fabaceae rosids Viridiplantae
Lupinus elegans 53226 Fabaceae rosids Viridiplantae
Lupinus luteus 3873 Fabaceae rosids Viridiplantae
Lupinus mutabilis 53232 Fabaceae rosids Viridiplantae
Lupinus nanus 53233 Fabaceae rosids Viridiplantae
Lupinus pilosus 53237 Fabaceae rosids Viridiplantae
Lupinus sericeus 61075 Fabaceae rosids Viridiplantae
Lupinus subcarnosus 3869 Fabaceae rosids Viridiplantae
Lupinus texensis 28959 Fabaceae rosids Viridiplantae
Maackia amurensis 37501 Fabaceae rosids Viridiplantae
Macroptilium bracteatum 260883 Fabaceae rosids Viridiplantae
Macroptilium lathyroides 260885 Fabaceae rosids Viridiplantae
Macroptilium martii 77316 Fabaceae rosids Viridiplantae
Medicago sativa 3879 Fabaceae rosids Viridiplantae
Millettia dielsiana 185709 Fabaceae rosids Viridiplantae
Mucuna pruriens 157652 Fabaceae rosids Viridiplantae
Neonotonia wightii 103823 Fabaceae rosids Viridiplantae
Neorautanenia amboensis 167619 Fabaceae rosids Viridiplantae
Ononis spinosa 58890 Fabaceae rosids Viridiplantae
Ormosia monosperma 53907 Fabaceae rosids Viridiplantae
Otholobium bolusii 1094751 Fabaceae rosids Viridiplantae
Otholobium bracteolatum 458346 Fabaceae rosids Viridiplantae
Otholobium candicans 53909 Fabaceae rosids Viridiplantae
Otholobium hirtum 53909 Fabaceae rosids Viridiplantae
Otholobium spicatum 1237764 Fabaceae rosids Viridiplantae
Otholobium striatum 458349 Fabaceae rosids Viridiplantae
Otholobium uncinatum 53909 Fabaceae rosids Viridiplantae
Otholobium wilmsii 1237765 Fabaceae rosids Viridiplantae
Pericopsis laxiflora 53916 Fabaceae rosids Viridiplantae
Phaseolus coccineus 3886 Fabaceae rosids Viridiplantae
Phaseolus lunatus 3884 Fabaceae rosids Viridiplantae
Phaseolus vulgaris 3885 Fabaceae rosids Viridiplantae
Prunus spp. 3754 Rosaceae rosids Viridiplantae
Pseudeminia comosa 45681 Fabaceae rosids Viridiplantae
Pseudoeriosema borianii 3803 Fabaceae rosids Viridiplantae
Pseudovigna argentea 109173 Fabaceae rosids Viridiplantae
Psoralea aculeata 379280 Fabaceae rosids Viridiplantae
Psoralea arborea 100167 Fabaceae rosids Viridiplantae
Psoralea axillaris 1237782 Fabaceae rosids Viridiplantae
Psoralea effusa 100167 Fabaceae rosids Viridiplantae
Psoralea fascicularis 100167 Fabaceae rosids Viridiplantae
Psoralea laxa 100167 Fabaceae rosids Viridiplantae
Psoralea oligophylla 100167 Fabaceae rosids Viridiplantae
Psoralea repens 100167 Fabaceae rosids Viridiplantae
Pterocarpus angolensis 182271 Fabaceae rosids Viridiplantae
Pueraria lobata 3893 Fabaceae rosids Viridiplantae
Pueraria mirifica 861244 Fabaceae rosids Viridiplantae
Pueraria montana var. lobata 3893 Fabaceae rosids Viridiplantae
Pueraria phaseoloides 109224 Fabaceae rosids Viridiplantae
Retama monosperma 49836 Fabaceae rosids Viridiplantae
Retama raetam 49837 Fabaceae rosids Viridiplantae
Rhynchosia caribaea 132460 Fabaceae rosids Viridiplantae
Rhynchosia densiflora 132460 Fabaceae rosids Viridiplantae
Rhynchosia hirsuta 132460 Fabaceae rosids Viridiplantae
Rhynchosia phaseoloides 132460 Fabaceae rosids Viridiplantae
Rhynchosia pyramidalis 132460 Fabaceae rosids Viridiplantae
Securidaca inappendiculata 4277 Polygalaceae rosids Viridiplantae
Sophora japonica 3897 Fabaceae rosids Viridiplantae
Sophora secundiflora 48122 Fabaceae rosids Viridiplantae
Stemphilium sp. No. 644
Strongylodon macrobotrys 167626 Fabaceae rosids Viridiplantae
Tephrosia toxicaria 3803 Fabaceae rosids Viridiplantae
Teyleria koordersii 157667 Fabaceae rosids Viridiplantae
Thermopsis alterniflora 49852 Fabaceae rosids Viridiplantae
Thermopsis macrophylla 114322 Fabaceae rosids Viridiplantae
Thermopsis mollis 49852 Fabaceae rosids Viridiplantae
Thermopsis rhombifolia 61122 Fabaceae rosids Viridiplantae
Thermopsis villosa 114325 Fabaceae rosids Viridiplantae
Trifolium campestre 97015 Fabaceae rosids Viridiplantae
Trifolium globosum 361919 Fabaceae rosids Viridiplantae
Trifolium pannonicum 97032 Fabaceae rosids Viridiplantae
Trifolium pratense 57577 Fabaceae rosids Viridiplantae
Trifolium repens 3899 Fabaceae rosids Viridiplantae
Trifolium spp. 3898 Fabaceae rosids Viridiplantae
Ulex boivinii 3901 Fabaceae rosids Viridiplantae
Ulex europaeus 3902 Fabaceae rosids Viridiplantae
Ulex gallii 183290 Fabaceae rosids Viridiplantae
Ulex genistoides 3901 Fabaceae rosids Viridiplantae
Ulex micranthus 183291 Fabaceae rosids Viridiplantae
Ulex minor 183318 Fabaceae rosids Viridiplantae
Ulex parviflorus 49854 Fabaceae rosids Viridiplantae
Vandasina retusa 556522 Fabaceae rosids Viridiplantae
Vigna angularis 3914 Fabaceae rosids Viridiplantae
Vigna mungo 3915 Fabaceae rosids Viridiplantae
Vigna radiata 157791 Fabaceae rosids Viridiplantae
Vigna subterranea 115715 Fabaceae rosids Viridiplantae
Wisteria brachybotrys 185975 Fabaceae rosids Viridiplantae
Zea mays L. 4577 Poaceae Liliopsida Viridiplantae

Human Protein / Gene in interaction

170 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL44 CHEMBL1741321 (1) CHEMBL1909136 (2)
1 / 0
P14061 Estradiol 17-beta-dehydrogenase 1 Enzyme CHEMBL44 CHEMBL957998 (1) CHEMBL957999 (1)
0 / 0
P33527 Multidrug resistance-associated protein 1 drugs CHEMBL44 CHEMBL2076461 (1) CHEMBL2076025 (1)
CHEMBL2076035 (1) CHEMBL2076038 (1)
CHEMBL2076039 (1) CHEMBL2078146 (1)
0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor CHEMBL44 CHEMBL1613992 (2) CHEMBL1613995 (1)
CHEMBL1738132 (1)
7 / 44
Q16637 Survival motor neuron protein Unclassified protein CHEMBL44 CHEMBL1613842 (3)
4 / 2
Q9Y6L6 Solute carrier organic anion transporter family member 1B1 Electrochemical transporter CHEMBL44 CHEMBL2169429 (1)
1 / 0
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein CHEMBL44 CHEMBL2169431 (1)
0 / 0
Q99700 Ataxin-2 Unclassified protein CHEMBL44 CHEMBL1794367 (1)
1 / 1
P14618 Pyruvate kinase PKM Enzyme CHEMBL44 CHEMBL1614177 (1) CHEMBL1614265 (1)
0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor CHEMBL44 CHEMBL1909139 (2)
0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL44 CHEMBL1909131 (2)
0 / 3
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) CHEMBL44 CHEMBL1909190 (2)
2 / 2
P08246 Neutrophil elastase S1A CHEMBL44 CHEMBL1909195 (2)
2 / 1
P33765 Adenosine receptor A3 Adenosine receptor CHEMBL44 CHEMBL643650 (1) CHEMBL1909215 (2)
0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 CHEMBL44 CHEMBL1909201 (2)
0 / 0
P06746 DNA polymerase beta Enzyme CHEMBL44 CHEMBL1614079 (1)
0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor CHEMBL44 CHEMBL1909176 (2)
0 / 0
P04062 Glucosylceramidase Enzyme CHEMBL44 CHEMBL1613818 (4)
6 / 4
P29466 Caspase-1 C14 CHEMBL44 CHEMBL1909193 (2)
0 / 0
P17252 Protein kinase C alpha type Alpha CHEMBL44 CHEMBL763598 (1) CHEMBL1909198 (2)
0 / 0
P27361 Mitogen-activated protein kinase 3 Erk CHEMBL44 CHEMBL1909199 (2)
0 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 CHEMBL44 CHEMBL1794524 (2) CHEMBL1794552 (2)
0 / 0
P14780 Matrix metalloproteinase-9 M10A CHEMBL44 CHEMBL1909197 (2)
2 / 2
P02545 Prelamin-A/C Unclassified protein CHEMBL44 CHEMBL1614310 (1) CHEMBL1614544 (2)
11 / 10
P00519 Tyrosine-protein kinase ABL1 Abl CHEMBL44 CHEMBL847372 (1) CHEMBL846550 (1)
1 / 4
P16473 Thyrotropin receptor Glycohormone receptor CHEMBL44 CHEMBL1614281 (1) CHEMBL1614361 (1)
3 / 2
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase CHEMBL44 CHEMBL991725 (1) CHEMBL990777 (1)
1 / 1
P10828 Thyroid hormone receptor beta NR1A2 CHEMBL44 CHEMBL1794561 (1)
3 / 1
P19793 Retinoic acid receptor RXR-alpha NR2B1 CHEMBL44 CHEMBL1794371 (2) CHEMBL1794471 (2)
0 / 0
P00918 Carbonic anhydrase 2 Lyase CHEMBL44 CHEMBL1909123 (2)
1 / 2
P05091 Aldehyde dehydrogenase, mitochondrial Oxidoreductase CHEMBL44 CHEMBL641179 (1) CHEMBL693590 (1)
CHEMBL693591 (1) CHEMBL693592 (1)
CHEMBL693593 (1)
1 / 1
P07550 Beta-2 adrenergic receptor Adrenergic receptor CHEMBL44 CHEMBL1909092 (2)
0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase CHEMBL44 CHEMBL879881 (1) CHEMBL689869 (1)
CHEMBL689870 (1) CHEMBL689871 (1)
CHEMBL731143 (1) CHEMBL1909169 (2)
1 / 1
P25021 Histamine H2 receptor Histamine receptor CHEMBL44 CHEMBL1909157 (2)
0 / 0
P35367 Histamine H1 receptor Histamine receptor CHEMBL44 CHEMBL1909156 (2)
0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine CHEMBL44 CHEMBL1909143 (2)
1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor CHEMBL44 CHEMBL1909174 (2)
0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor CHEMBL44 CHEMBL1909090 (2)
0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor CHEMBL44 CHEMBL1909093 (2)
0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim CHEMBL44 CHEMBL862675 (1) CHEMBL862676 (1)
0 / 0
P08183 Multidrug resistance protein 1 drug CHEMBL44 CHEMBL1827948 (1) CHEMBL2075620 (1)
CHEMBL2076328 (1) CHEMBL2075832 (1)
1 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor CHEMBL44 CHEMBL1909127 (2)
0 / 0
P06241 Tyrosine-protein kinase Fyn Src CHEMBL44 CHEMBL1909204 (2)
0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr CHEMBL44 CHEMBL1909202 (2)
0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL44 CHEMBL1614027 (1) CHEMBL1741325 (1)
CHEMBL1909135 (2)
0 / 1
P14635 G2/mitotic-specific cyclin-B1 Other cytosolic protein CHEMBL44 CHEMBL661122 (1)
0 / 0
P06493 Cyclin-dependent kinase 1 Cdc2 CHEMBL44 CHEMBL661122 (1)
0 / 0
P11802 Cyclin-dependent kinase 4 CMGC serine/threonine protein kinase family CHEMBL44 CHEMBL666304 (1)
1 / 3
P24385 G1/S-specific cyclin-D1 Other cytosolic protein CHEMBL44 CHEMBL666304 (1)
1 / 10
O75828 Carbonyl reductase [NADPH] 3 Enzyme CHEMBL44 CHEMBL1004501 (1) CHEMBL1004502 (1)
CHEMBL1004503 (1)
0 / 0
P54132 Bloom syndrome protein Enzyme CHEMBL44 CHEMBL1614522 (1) CHEMBL1614067 (1)
1 / 2
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL44 CHEMBL677209 (1) CHEMBL679549 (1)
CHEMBL675515 (1) CHEMBL677887 (1)
CHEMBL939337 (1) CHEMBL1012122 (1)
CHEMBL941404 (2) CHEMBL941412 (1)
CHEMBL970971 (1) CHEMBL1100791 (1)
CHEMBL1909203 (2)
1 / 11
P11387 DNA topoisomerase 1 Isomerase CHEMBL44 CHEMBL919339 (1) CHEMBL919340 (1)
CHEMBL919341 (1) CHEMBL919342 (1)
CHEMBL920770 (1) CHEMBL920771 (1)
0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase CHEMBL44 CHEMBL920757 (1) CHEMBL920758 (1)
CHEMBL920759 (1) CHEMBL920760 (1)
CHEMBL920777 (1) CHEMBL920778 (1)
CHEMBL1014685 (1) CHEMBL1014688 (1)
CHEMBL1014689 (1) CHEMBL1014693 (1)
CHEMBL1014697 (1)
0 / 0
P11473 Vitamin D3 receptor NR1I1 CHEMBL44 CHEMBL1794376 (1)
2 / 3
P14416 D(2) dopamine receptor Dopamine receptor CHEMBL44 CHEMBL1909140 (2)
2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase CHEMBL44 CHEMBL1008496 (1) CHEMBL1909130 (2)
0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor CHEMBL44 CHEMBL1909120 (2)
0 / 0
P41145 Kappa-type opioid receptor Opioid receptor CHEMBL44 CHEMBL1909181 (2)
0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor CHEMBL44 CHEMBL1909164 (2)
0 / 0
P29274 Adenosine receptor A2a Adenosine receptor CHEMBL44 CHEMBL1909214 (2)
0 / 0
P11926 Ornithine decarboxylase Lyase CHEMBL44 CHEMBL970064 (1)
0 / 0
P11474 Steroid hormone receptor ERR1 NR3B1 CHEMBL44 CHEMBL886438 (1)
0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor CHEMBL44 CHEMBL1909175 (2)
0 / 0
Q9Y3R4 Sialidase-2 Enzyme CHEMBL44 CHEMBL1100507 (1)
0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor CHEMBL44 CHEMBL1909096 (2)
1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr CHEMBL44 CHEMBL1909118 (2)
0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor CHEMBL44 CHEMBL1909166 (2)
1 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL44 CHEMBL1614458 (2)
0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme CHEMBL44 CHEMBL1794495 (1)
2 / 2
P04278 Sex hormone-binding globulin Secreted protein CHEMBL44 CHEMBL922711 (1)
0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 CHEMBL44 CHEMBL1909133 (2)
0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor CHEMBL44 CHEMBL1614456 (1) CHEMBL1613803 (1)
0 / 0
P39748 Flap endonuclease 1 Enzyme CHEMBL44 CHEMBL1794486 (1)
0 / 0
P16152 Carbonyl reductase [NADPH] 1 Enzyme CHEMBL44 CHEMBL1004498 (1) CHEMBL1004499 (1)
CHEMBL1004500 (1)
0 / 0
O75496 Geminin Unclassified protein CHEMBL44 CHEMBL2114780 (1)
0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein CHEMBL44 CHEMBL1613838 (2)
0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme CHEMBL44 CHEMBL2114807 (1)
4 / 2
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase CHEMBL44 CHEMBL1909158 (2)
0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor CHEMBL44 CHEMBL1909088 (2)
0 / 0
P21917 D(4) dopamine receptor Dopamine receptor CHEMBL44 CHEMBL1909142 (2)
0 / 0
P30988 Calcitonin receptor Calcitonin receptor CHEMBL44 CHEMBL1909101 (2)
0 / 0
P35462 D(3) dopamine receptor Dopamine receptor CHEMBL44 CHEMBL1909141 (2)
1 / 0
P41143 Delta-type opioid receptor Opioid receptor CHEMBL44 CHEMBL1909180 (2)
0 / 0
Q92731 Estrogen receptor beta NR3A2 CHEMBL44 CHEMBL679353 (1) CHEMBL677954 (1)
CHEMBL678669 (1) CHEMBL677744 (1)
CHEMBL673864 (1) CHEMBL682160 (1)
CHEMBL682161 (1) CHEMBL682162 (1)
CHEMBL876871 (1) CHEMBL682168 (1)
CHEMBL682169 (1) CHEMBL678095 (1)
CHEMBL677051 (1) CHEMBL677223 (1)
CHEMBL708330 (1) CHEMBL708331 (1)
CHEMBL847349 (1) CHEMBL850899 (1)
CHEMBL850379 (1) CHEMBL850380 (1)
CHEMBL826030 (1) CHEMBL828540 (2)
CHEMBL832634 (1) CHEMBL831137 (1)
CHEMBL829091 (1) CHEMBL829115 (1)
CHEMBL830453 (2) CHEMBL830748 (1)
CHEMBL831723 (1) CHEMBL838181 (1)
CHEMBL880931 (1) CHEMBL884157 (1)
CHEMBL868723 (1) CHEMBL868724 (1)
CHEMBL860987 (1) CHEMBL860991 (1)
CHEMBL860992 (1) CHEMBL860995 (1)
CHEMBL860997 (1) CHEMBL909844 (1)
CHEMBL909845 (1) CHEMBL888712 (1)
CHEMBL891639 (1) CHEMBL895879 (1)
CHEMBL898604 (1) CHEMBL898607 (1)
CHEMBL965155 (1) CHEMBL1008128 (1)
CHEMBL1664695 (1) CHEMBL1909146 (2)
0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor CHEMBL44 CHEMBL1909104 (2)
0 / 0
P15121 Aldose reductase Enzyme CHEMBL44 CHEMBL1942674 (1)
0 / 0
P25101 Endothelin-1 receptor Endothelin receptor CHEMBL44 CHEMBL1909144 (2)
0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor CHEMBL44 CHEMBL1909100 (2)
0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor CHEMBL44 CHEMBL1909167 (2)
1 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor CHEMBL44 CHEMBL1909129 (2)
0 / 0
P08311 Cathepsin G S1A CHEMBL44 CHEMBL1909194 (2)
0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor CHEMBL44 CHEMBL1909110 (2)
1 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL44 CHEMBL2114788 (1) CHEMBL2114931 (1)
0 / 0
P03956 Interstitial collagenase M10A CHEMBL44 CHEMBL1909196 (2)
0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor CHEMBL44 CHEMBL1909119 (2)
0 / 0
Q9NPD5 Solute carrier organic anion transporter family member 1B3 Electrochemical transporter CHEMBL44 CHEMBL2169430 (1)
1 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein CHEMBL44 CHEMBL1794423 (1) CHEMBL1963893 (1)
0 / 0
P04150 Glucocorticoid receptor NR3C1 CHEMBL44 CHEMBL1052488 (1) CHEMBL1052489 (1)
CHEMBL1052492 (1) CHEMBL1052494 (1)
CHEMBL1909150 (2)
0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor CHEMBL44 CHEMBL1909171 (2)
2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor CHEMBL44 CHEMBL1909170 (2)
0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 CHEMBL44 CHEMBL827396 (1) CHEMBL987972 (1)
2 / 2
P21554 Cannabinoid receptor 1 Cannabinoid receptor CHEMBL44 CHEMBL1909122 (2)
0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin CHEMBL44 CHEMBL1909109 (2)
2 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 CHEMBL44 CHEMBL1059360 (1) CHEMBL1059361 (1)
CHEMBL1794510 (2)
5 / 3
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily CHEMBL44 CHEMBL1909205 (2)
5 / 10
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor CHEMBL44 CHEMBL1909172 (2)
1 / 0
P21452 Substance-K receptor Neurokinin receptor CHEMBL44 CHEMBL1909114 (2)
0 / 0
P12931 Proto-oncogene tyrosine-protein kinase Src Src CHEMBL44 CHEMBL816861 (1) CHEMBL843059 (1)
0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor CHEMBL44 CHEMBL1909125 (2)
0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor CHEMBL44 CHEMBL1909126 (2)
3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor CHEMBL44 CHEMBL1909108 (2)
0 / 0
P04745 Alpha-amylase 1 Enzyme CHEMBL44 CHEMBL964479 (2)
0 / 0
Q96RI1 Bile acid receptor NR1H4 CHEMBL44 CHEMBL1794437 (2)
0 / 0
Q13133 Oxysterols receptor LXR-alpha NR1H3 CHEMBL44 CHEMBL933514 (1)
0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor CHEMBL44 CHEMBL1909124 (2)
1 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL44 CHEMBL1613808 (2) CHEMBL1909200 (2)
0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme CHEMBL44 CHEMBL1909207 (2)
2 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL44 CHEMBL1741322 (1) CHEMBL1909132 (2)
0 / 0
P55055 Oxysterols receptor LXR-beta NR1H3 CHEMBL44 CHEMBL933515 (1)
0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette CHEMBL44 CHEMBL1687393 (1) CHEMBL1687394 (1)
CHEMBL2076473 (1) CHEMBL2076243 (1)
CHEMBL2076824 (1) CHEMBL2076838 (1)
CHEMBL2075868 (1) CHEMBL2078552 (1)
2 / 0
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein CHEMBL44 CHEMBL1006005 (1)
1 / 1
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL44 CHEMBL1614038 (5)
2 / 2
O15118 Niemann-Pick C1 protein Unclassified protein CHEMBL44 CHEMBL1614342 (2)
1 / 1
Q01453 Peripheral myelin protein 22 Unclassified protein CHEMBL44 CHEMBL1614171 (1)
5 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL44 CHEMBL1738588 (1) CHEMBL1738675 (1)
CHEMBL1737868 (1) CHEMBL1738317 (1)
0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A CHEMBL44 CHEMBL1909186 (2)
0 / 0
P03372 Estrogen receptor NR3A1 CHEMBL44 CHEMBL679353 (1) CHEMBL676806 (1)
CHEMBL883442 (1) CHEMBL676811 (1)
CHEMBL676818 (1) CHEMBL676819 (1)
CHEMBL679323 (1) CHEMBL679893 (1)
CHEMBL682303 (1) CHEMBL708330 (1)
CHEMBL708331 (1) CHEMBL841902 (1)
CHEMBL841903 (1) CHEMBL841904 (1)
CHEMBL847349 (1) CHEMBL850899 (1)
CHEMBL850379 (1) CHEMBL850380 (1)
CHEMBL826030 (1) CHEMBL827788 (2)
CHEMBL832786 (1) CHEMBL831155 (1)
CHEMBL829540 (1) CHEMBL829115 (1)
CHEMBL830453 (2) CHEMBL830748 (1)
CHEMBL831723 (1) CHEMBL881884 (1)
CHEMBL884157 (1) CHEMBL863381 (1)
CHEMBL868724 (1) CHEMBL860989 (1)
CHEMBL860991 (1) CHEMBL860997 (1)
CHEMBL909843 (1) CHEMBL909845 (1)
CHEMBL888711 (1) CHEMBL891640 (1)
CHEMBL895878 (1) CHEMBL898603 (1)
CHEMBL898606 (1) CHEMBL965154 (1)
CHEMBL946607 (1) CHEMBL999946 (1)
CHEMBL999947 (1) CHEMBL1664694 (1)
CHEMBL1794364 (2) CHEMBL1794542 (1)
CHEMBL1909145 (2)
1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor CHEMBL44 CHEMBL1909091 (2)
1 / 0
P22303 Acetylcholinesterase Hydrolase CHEMBL44 CHEMBL1909212 (2)
1 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor CHEMBL44 CHEMBL1909211 (2)
0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor CHEMBL44 CHEMBL1909105 (2)
0 / 0
P35372 Mu-type opioid receptor Opioid receptor CHEMBL44 CHEMBL1909182 (2)
0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor CHEMBL44 CHEMBL1909173 (2)
0 / 0
P25103 Substance-P receptor Neurokinin receptor CHEMBL44 CHEMBL1909113 (2)
0 / 0
P25105 Platelet-activating factor receptor PAF receptor CHEMBL44 CHEMBL1909187 (2)
0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor CHEMBL44 CHEMBL1909168 (2)
0 / 0
O95718 Steroid hormone receptor ERR2 NR3B2 CHEMBL44 CHEMBL886439 (1)
1 / 1
Q02880 DNA topoisomerase 2-beta Isomerase CHEMBL44 CHEMBL920238 (1)
0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme CHEMBL44 CHEMBL1614240 (2)
0 / 0
Q8WUI4 Histone deacetylase 7 Hydrolase CHEMBL44 CHEMBL1267835 (1)
0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt CHEMBL44 CHEMBL853526 (1)
4 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL44 CHEMBL1613777 (2) CHEMBL1741323 (1)
CHEMBL1909134 (2)
1 / 1
P37059 Estradiol 17-beta-dehydrogenase 2 Enzyme CHEMBL44 CHEMBL958788 (1) CHEMBL958789 (1)
0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL44 CHEMBL1614108 (2) CHEMBL1613886 (2)
CHEMBL1741324 (1) CHEMBL1909138 (2)
0 / 1
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 CHEMBL44 CHEMBL1909137 (2)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL44 CHEMBL1614421 (5) CHEMBL1614502 (1)
4 / 3
Q99549 M-phase phosphoprotein 8 Unclassified protein CHEMBL44 CHEMBL1738402 (1)
0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL44 CHEMBL2114890 (2)
0 / 0
O43451 Maltase-glucoamylase, intestinal Hydrolase CHEMBL44 CHEMBL646886 (1) CHEMBL646887 (1)
CHEMBL872366 (1)
0 / 0
P10275 Androgen receptor NR3C4 CHEMBL44 CHEMBL1052486 (1) CHEMBL1052487 (1)
CHEMBL1052490 (1) CHEMBL1052491 (1)
CHEMBL1052493 (1) CHEMBL1794321 (1)
CHEMBL1794560 (1)
3 / 4
P23975 Sodium-dependent noradrenaline transporter Norepinephrine CHEMBL44 CHEMBL1909094 (2)
1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor CHEMBL44 CHEMBL1909087 (2)
0 / 0
P30542 Adenosine receptor A1 Adenosine receptor CHEMBL44 CHEMBL1909213 (2)
0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor CHEMBL44 CHEMBL1909089 (2)
0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 CHEMBL44 CHEMBL1909116 (2)
1 / 1
P06239 Tyrosine-protein kinase Lck Src CHEMBL44 CHEMBL1909206 (2)
0 / 1
P35869 Aryl hydrocarbon receptor Transcription Factor CHEMBL44 CHEMBL2114849 (2)
0 / 0
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor CHEMBL44 CHEMBL1909128 (2)
0 / 0
P43405 Tyrosine-protein kinase SYK Syk CHEMBL44 CHEMBL1022010 (1)
0 / 0
Q06278 Aldehyde oxidase Enzyme CHEMBL44 CHEMBL1640077 (1)
0 / 1
P40225 Thrombopoietin Unclassified protein CHEMBL44 CHEMBL1614086 (1) CHEMBL1614034 (1)
1 / 1
P56937 3-keto-steroid reductase Enzyme CHEMBL44 CHEMBL1106724 (1) CHEMBL1106725 (1)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL44 CHEMBL1738442 (1)
0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL44 CHEMBL1614364 (1)
1 / 1
O00255 Menin Unclassified protein CHEMBL44 CHEMBL1614257 (2) CHEMBL1614531 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL44 CHEMBL1614257 (2) CHEMBL1614531 (1)
1 / 3
P27338 Amine oxidase [flavin-containing] B Oxidoreductase CHEMBL44 CHEMBL879881 (1) CHEMBL689869 (1)
CHEMBL689870 (1) CHEMBL689871 (1)
CHEMBL731143 (1)
0 / 0
P42684 Abelson tyrosine-protein kinase 2 Abl CHEMBL44 CHEMBL846550 (1)
0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL44 CHEMBL2114738 (1)
0 / 0

CTD interaction (1967)

compound gene gene name gene description interaction interaction type form reference
pmid
D019833 18 ABAT
GABA-AT
GABAT
NPD009
4-aminobutyrate aminotransferase (EC:2.6.1.19 2.6.1.22) ESR2 promotes the reaction [Genistein results in decreased expression of ABAT protein] decreases expression
/ increases reaction
protein 20884965
D019833 18 ABAT
GABA-AT
GABAT
NPD009
4-aminobutyrate aminotransferase (EC:2.6.1.19 2.6.1.22) Genistein results in decreased expression of ABAT protein decreases expression
protein 20884965
D019833 19 ABCA1
ABC-1
ABC1
CERP
HDLDT1
TGD
ATP-binding cassette, sub-family A (ABC1), member 1 [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ABCA1 mRNA affects cotreatment
/ decreases expression
mRNA 16963248
D019833 19 ABCA1
ABC-1
ABC1
CERP
HDLDT1
TGD
ATP-binding cassette, sub-family A (ABC1), member 1 Genistein results in increased expression of ABCA1 mRNA increases expression
mRNA 18847459
D019833 5243 ABCB1
ABC20
CD243
CLCS
GP170
MDR1
P-GP
PGY1
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) Genistein results in increased expression of ABCB1 protein increases expression
protein 18634814
D019833 4363 ABCC1
ABC29
ABCC
GS-X
MRP
MRP1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Genistein affects the activity of ABCC1 protein affects activity
protein 9334814
D019833 4363 ABCC1
ABC29
ABCC
GS-X
MRP
MRP1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Genistein analog results in decreased activity of ABCC1 protein decreases activity
protein 15916776
D019833 4363 ABCC1
ABC29
ABCC
GS-X
MRP
MRP1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Genistein results in decreased activity of ABCC1 protein decreases activity
protein 15581599
D019833 85320 ABCC11
EWWD
MRP8
WW
ATP-binding cassette, sub-family C (CFTR/MRP), member 11 Genistein results in increased expression of ABCC11 mRNA increases expression
mRNA 20884965
D019833 150000 ABCC13
C21orf73
PRED6
ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene Genistein results in increased expression of ABCC13 mRNA increases expression
mRNA 16474171
D019833 1244 ABCC2
ABC30
CMOAT
DJS
MRP2
cMRP
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 Genistein inhibits the reaction [ABCC2 protein affects the export of ochratoxin A] affects export
/ decreases reaction
protein 15955639
D019833 1244 ABCC2
ABC30
CMOAT
DJS
MRP2
cMRP
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 Genistein promotes the reaction [RXRA protein binds to ABCC2 promoter] affects binding
/ increases reaction
promoter 21689630
D019833 1244 ABCC2
ABC30
CMOAT
DJS
MRP2
cMRP
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 Genistein results in increased expression of ABCC2 mRNA increases expression
mRNA 21689630
D019833 1244 ABCC2
ABC30
CMOAT
DJS
MRP2
cMRP
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 Genistein results in increased expression of ABCC2 protein increases expression
protein 21689630
D019833 1244 ABCC2
ABC30
CMOAT
DJS
MRP2
cMRP
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 resveratrol inhibits the reaction [Genistein promotes the reaction [RXRA protein binds to ABCC2 promoter]] affects binding
/ decreases reaction
/ increases reaction
promoter 21689630
D019833 1244 ABCC2
ABC30
CMOAT
DJS
MRP2
cMRP
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 resveratrol inhibits the reaction [Genistein results in increased expression of ABCC2 mRNA] decreases reaction
/ increases expression
mRNA 21689630
D019833 1244 ABCC2
ABC30
CMOAT
DJS
MRP2
cMRP
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 resveratrol inhibits the reaction [Genistein results in increased expression of ABCC2 protein] decreases reaction
/ increases expression
protein 21689630
D019833 8714 ABCC3
ABC31
EST90757
MLP2
MOAT-D
MRP3
cMOAT2
ATP-binding cassette, sub-family C (CFTR/MRP), member 3 Genistein results in decreased expression of ABCC3 mRNA decreases expression
mRNA 19371625
D019833 83451 ABHD11
WBSCR21
abhydrolase domain containing 11 Genistein results in increased expression of ABHD11 mRNA increases expression
mRNA 23019147
D019833 10006 ABI1
ABI-1
ABLBP4
E3B1
NAP1BP
SSH3BP
SSH3BP1
abl-interactor 1 Genistein results in increased expression of ABI1 mRNA increases expression
mRNA 15256057
D019833 1238 ACKR2
CCBP2
CCR10
CCR9
CMKBR9
D6
hD6
atypical chemokine receptor 2 Genistein results in decreased expression of ACKR2 mRNA decreases expression
mRNA 19371625
D019833 47 ACLY
ACL
ATPCL
CLATP
ATP citrate lyase (EC:2.3.3.8) ESR2 promotes the reaction [Genistein results in decreased expression of ACLY protein] decreases expression
/ increases reaction
protein 20884965
D019833 47 ACLY
ACL
ATPCL
CLATP
ATP citrate lyase (EC:2.3.3.8) Genistein results in decreased expression of ACLY protein decreases expression
protein 20884965
D019833 47 ACLY
ACL
ATPCL
CLATP
ATP citrate lyase (EC:2.3.3.8) Genistein results in increased expression of ACLY mRNA increases expression
mRNA 20706672
D019833 51 ACOX1
ACOX
PALMCOX
SCOX
acyl-CoA oxidase 1, palmitoyl (EC:1.3.3.6) ESR2 promotes the reaction [Genistein results in decreased expression of ACOX1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 51 ACOX1
ACOX
PALMCOX
SCOX
acyl-CoA oxidase 1, palmitoyl (EC:1.3.3.6) Genistein results in decreased expression of ACOX1 protein decreases expression
protein 20884965
D019833 55 ACPP
5'-NT
ACP-3
ACP3
PAP
acid phosphatase, prostate (EC:3.1.3.2 3.1.3.5) Genistein results in decreased expression of ACPP mRNA decreases expression
mRNA 12391264
D019833 2181 ACSL3
ACS3
FACL3
PRO2194
acyl-CoA synthetase long-chain family member 3 (EC:6.2.1.3) Genistein results in increased expression of ACSL3 mRNA increases expression
mRNA 18847459
D019833 59 ACTA2
AAT6
ACTSA
MYMY5
actin, alpha 2, smooth muscle, aorta Genistein results in decreased expression of ACTA2 mRNA decreases expression
mRNA 20884965
D019833 345651 ACTBL2
ACT
actin, beta-like 2 ESR1 promotes the reaction [Genistein results in decreased expression of ACTBL2 protein] decreases expression
/ increases reaction
protein 20884965
D019833 345651 ACTBL2
ACT
actin, beta-like 2 Genistein results in decreased expression of ACTBL2 protein decreases expression
protein 20884965
D019833 95 ACY1
ACY-1
ACY1D
aminoacylase 1 (EC:3.5.1.14) ESR2 promotes the reaction [Genistein results in increased expression of ACY1 protein] increases expression
/ increases reaction
protein 20884965
D019833 95 ACY1
ACY-1
ACY1D
aminoacylase 1 (EC:3.5.1.14) Genistein results in increased expression of ACY1 protein increases expression
protein 20884965
D019833 8751 ADAM15
MDC15
ADAM metallopeptidase domain 15 Genistein results in decreased expression of ADAM15 mRNA decreases expression
mRNA 16705744
D019833 11173 ADAMTS7
ADAM-TS_7
ADAM-TS7
ADAMTS-7
ADAM metallopeptidase with thrombospondin type 1 motif, 7 (EC:3.4.24.-) Genistein results in increased expression of ADAMTS7 mRNA increases expression
mRNA 18847459
D019833 56999 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9 Genistein results in increased expression of ADAMTS9 mRNA increases expression
mRNA 19371625
D019833 119 ADD2
ADDB
adducin 2 (beta) [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ADD2 mRNA affects cotreatment
/ decreases expression
mRNA 16963248
D019833 10974 ADIRF
AFRO
APM2
C10orf116
apM-2
adipogenesis regulatory factor Genistein results in increased expression of ADIRF mRNA increases expression
mRNA 20884965
D019833 152 ADRA2C
ADRA2L2
ADRA2RL2
ADRARL2
ALPHA2CAR
adrenoceptor alpha 2C Genistein results in increased expression of ADRA2C mRNA increases expression
mRNA 23019147
D019833 158 ADSL
AMPS
ASASE
ASL
adenylosuccinate lyase (EC:4.3.2.2) ESR2 promotes the reaction [Genistein results in decreased expression of ADSL protein] decreases expression
/ increases reaction
protein 20884965
D019833 158 ADSL
AMPS
ASASE
ASL
adenylosuccinate lyase (EC:4.3.2.2) Genistein results in decreased expression of ADSL protein decreases expression
protein 20884965
D019833 10555 AGPAT2
1-AGPAT2
BSCL
BSCL1
LPAAB
LPAAT-beta
1-acylglycerol-3-phosphate O-acyltransferase 2 (EC:2.3.1.51) Genistein results in increased expression of AGPAT2 mRNA increases expression
mRNA 23019147
D019833 10551 AGR2
AG2
GOB-4
HAG-2
PDIA17
XAG-2
anterior gradient 2 Genistein results in increased expression of AGR2 mRNA increases expression
mRNA 16474171
D019833 196 AHR
bHLHe76
aryl hydrocarbon receptor Genistein affects the activity of AHR protein affects activity
protein 19286049
D019833 196 AHR
bHLHe76
aryl hydrocarbon receptor Genistein binds to AHR protein affects binding
protein 20436506
D019833 196 AHR
bHLHe76
aryl hydrocarbon receptor [Genistein co-treated with Methylcholanthrene] affects the activity of AHR protein affects activity
/ affects cotreatment
protein 19286049
D019833 196 AHR
bHLHe76
aryl hydrocarbon receptor [Genistein co-treated with Tetrachlorodibenzodioxin] affects the activity of AHR protein affects activity
/ affects cotreatment
protein 19286049
D019833 196 AHR
bHLHe76
aryl hydrocarbon receptor Genistein inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of AHR protein] affects localization
/ decreases reaction
protein 20057149
D019833 205 AK4
AK_4
AK3
AK3L1
AK3L2
adenylate kinase 4 (EC:2.7.4.10 2.7.4.6) Genistein results in increased expression of AK4 mRNA increases expression
mRNA 23019147
D019833 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Genistein binds to AKT1 protein affects binding
protein 16789737
D019833 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Genistein inhibits the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of AKT1 protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 21078540
D019833 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Genistein inhibits the reaction [EGF protein results in increased activity of AKT1 protein] decreases reaction
/ increases activity
protein 18431742
D019833 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Genistein results in decreased phosphorylation of AKT1 protein decreases phosphorylation
protein 15829497
18431742
19038232
21078540
D019833 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) [[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased activity of FOXO3 protein decreases activity
/ increases activity
/ increases expression
protein 18431742
D019833 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) [[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased expression of TP53 protein decreases activity
/ increases expression
protein 18431742
D019833 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Tretinoin inhibits the reaction [Genistein results in decreased phosphorylation of AKT1 protein] decreases phosphorylation
/ decreases reaction
protein 19038232
D019833 208 AKT2
HIHGHH
PKBB
PKBBETA
PRKBB
RAC-BETA
v-akt murine thymoma viral oncogene homolog 2 (EC:2.7.11.1) Genistein results in decreased expression of AKT2 mRNA decreases expression
mRNA 15257099
D019833 220 ALDH1A3
ALDH1A6
ALDH6
MCOP8
RALDH3
aldehyde dehydrogenase 1 family, member A3 (EC:1.2.1.5) Genistein results in decreased expression of ALDH1A3 mRNA decreases expression
mRNA 15378649
D019833 224 ALDH3A2
ALDH10
FALDH
SLS
aldehyde dehydrogenase 3 family, member A2 (EC:1.2.1.3) Genistein results in increased expression of ALDH3A2 mRNA increases expression
mRNA 18847459
D019833 229 ALDOB
ALDB
ALDO2
aldolase B, fructose-bisphosphate (EC:4.1.2.13) Genistein results in decreased expression of ALDOB mRNA decreases expression
mRNA 16705744
D019833 248 ALPI
IAP
alkaline phosphatase, intestinal (EC:3.1.3.1) Genistein results in increased expression of ALPI mRNA increases expression
mRNA 23019147
D019833 249 ALPL
AP-TNAP
APTNAP
HOPS
TNAP
TNSALP
alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) fulvestrant inhibits the reaction [[Genistein binds to ESR1 protein] which results in increased activity of ALPL protein] affects binding
/ decreases reaction
/ increases activity
protein 12650720
D019833 249 ALPL
AP-TNAP
APTNAP
HOPS
TNAP
TNSALP
alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) [Genistein binds to ESR1 protein] which results in increased activity of ALPL protein affects binding
/ increases activity
protein 12650720
D019833 250 ALPP
ALP
PALP
PLAP
PLAP-1
alkaline phosphatase, placental (EC:3.1.3.1) Genistein results in increased expression of ALPP mRNA increases expression
mRNA 23019147
D019833 251 ALPPL2
ALPG
ALPPL
GCAP
alkaline phosphatase, placental-like 2 (EC:3.1.3.1) Genistein results in increased expression of ALPPL2 mRNA increases expression
mRNA 19371625
23019147
D019833 196394 AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae) Genistein results in increased expression of AMN1 mRNA increases expression
mRNA 18847459
D019833 271 AMPD2
adenosine monophosphate deaminase 2 (EC:3.5.4.6) Genistein results in increased expression of AMPD2 mRNA increases expression
mRNA 23019147
D019833 64682 ANAPC1
APC1
MCPR
TSG24
anaphase promoting complex subunit 1 Genistein results in increased expression of ANAPC1 mRNA increases expression
mRNA 19371625
D019833 284 ANGPT1
AGP1
AGPT
ANG1
angiopoietin 1 Genistein results in decreased expression of ANGPT1 mRNA decreases expression
mRNA 16705744
D019833 286 ANK1
ANK
SPH1
SPH2
ankyrin 1, erythrocytic Genistein results in decreased expression of ANK1 mRNA decreases expression
mRNA 16705744
D019833 54522 ANKRD16
ankyrin repeat domain 16 Genistein results in decreased expression of ANKRD16 mRNA decreases expression
mRNA 18847459
D019833 91074 ANKRD30A
NY-BR-1
ankyrin repeat domain 30A Genistein results in increased expression of ANKRD30A mRNA increases expression
mRNA 23019147
D019833 57730 ANKRD36B
KIAA1641
ankyrin repeat domain 36B ESR2 promotes the reaction [Genistein results in increased expression of ANKRD36B protein] increases expression
/ increases reaction
protein 20884965
D019833 57730 ANKRD36B
KIAA1641
ankyrin repeat domain 36B Genistein results in increased expression of ANKRD36B protein increases expression
protein 20884965
D019833 55107 ANO1
DOG1
ORAOV2
TAOS2
TMEM16A
anoctamin 1, calcium activated chloride channel Genistein results in increased expression of ANO1 mRNA increases expression
mRNA 19371625
23019147
D019833 8125 ANP32A
C15orf1
HPPCn
I1PP2A
LANP
MAPM
PHAP1
PHAPI
PP32
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A Genistein results in decreased expression of ANP32A mRNA decreases expression
mRNA 18847459
D019833 301 ANXA1
ANX1
LPC1
annexin A1 ESR2 promotes the reaction [Genistein results in decreased expression of ANXA1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 301 ANXA1
ANX1
LPC1
annexin A1 Genistein results in decreased expression of ANXA1 protein decreases expression
protein 20884965
D019833 306 ANXA3
ANX3
annexin A3 (EC:3.1.4.43) ESR2 promotes the reaction [Genistein results in decreased expression of ANXA3 protein] decreases expression
/ increases reaction
protein 20884965
D019833 306 ANXA3
ANX3
annexin A3 (EC:3.1.4.43) Genistein results in decreased expression of ANXA3 protein decreases expression
protein 20884965
D019833 8905 AP1S2
MGC:1902
MRX59
MRXS21
MRXSF
SIGMA1B
adaptor-related protein complex 1, sigma 2 subunit Genistein results in increased expression of AP1S2 mRNA increases expression
mRNA 16474171
D019833 317 APAF1
APAF-1
CED4
apoptotic peptidase activating factor 1 Genistein results in increased expression of APAF1 mRNA increases expression
mRNA 15256057
D019833 334 APLP2
APLP-2
APPH
APPL2
CDEBP
amyloid beta (A4) precursor-like protein 2 ESR1 promotes the reaction [Genistein results in decreased expression of APLP2 protein] decreases expression
/ increases reaction
protein 20884965
D019833 334 APLP2
APLP-2
APPH
APPL2
CDEBP
amyloid beta (A4) precursor-like protein 2 Genistein results in decreased expression of APLP2 mRNA decreases expression
mRNA 16705744
D019833 334 APLP2
APLP-2
APPH
APPL2
CDEBP
amyloid beta (A4) precursor-like protein 2 Genistein results in decreased expression of APLP2 protein decreases expression
protein 20884965
D019833 9582 APOBEC3B
A3B
APOBEC1L
ARCD3
ARP4
DJ742C19.2
PHRBNL
bK150C2.2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B Genistein results in increased expression of APOBEC3B mRNA increases expression
mRNA 16474171
D019833 347 APOD
apolipoprotein D Genistein results in increased expression of APOD mRNA increases expression
mRNA 20884965
D019833 353 APRT
AMP
APRTD
adenine phosphoribosyltransferase (EC:2.4.2.7) ESR2 promotes the reaction [Genistein results in increased expression of APRT protein] increases expression
/ increases reaction
protein 20884965
D019833 353 APRT
AMP
APRTD
adenine phosphoribosyltransferase (EC:2.4.2.7) Genistein results in increased expression of APRT protein increases expression
protein 20884965
D019833 358 AQP1
AQP-CHIP
CHIP28
CO
aquaporin 1 Genistein results in decreased expression of AQP1 mRNA decreases expression
mRNA 20706672
D019833 360 AQP3
AQP-3
GIL
aquaporin 3 (Gill blood group) Genistein results in increased expression of AQP3 mRNA increases expression
mRNA 20706672
D019833 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor Genistein results in decreased expression of AR mRNA decreases expression
mRNA 12391264
20706672
D019833 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor Genistein results in increased activity of and results in increased localization of AR protein increases activity
/ increases localization
protein 12391264
D019833 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor Genistein results in increased activity of AR protein mutant form increases activity
protein 12391264
D019833 367 AR
AIS
DHTR
HUMARA
HYSP1
KD
NR3C4
SBMA
SMAX1
TFM
androgen receptor Genistein results in increased expression of AR protein increases expression
protein 12391264
D019833 374 AREG
AR
CRDGF
SDGF
amphiregulin Genistein results in increased expression of AREG mRNA increases expression
mRNA 16474171
D019833 375 ARF1
ADP-ribosylation factor 1 Genistein results in decreased expression of ARF1 mRNA decreases expression
mRNA 16705744
D019833 396 ARHGDIA
GDIA1
NPHS8
RHOGDI
RHOGDI-1
Rho GDP dissociation inhibitor (GDI) alpha Genistein results in decreased expression of ARHGDIA mRNA decreases expression
mRNA 15159206
15757668
D019833 403 ARL3
ARFL3
ADP-ribosylation factor-like 3 Genistein results in increased expression of ARL3 mRNA increases expression
mRNA 16474171
18847459
D019833 83787 ARMC10
PNAS-112
PNAS112
SVH
armadillo repeat containing 10 ESR2 promotes the reaction [Genistein results in increased expression of ARMC10 protein] increases expression
/ increases reaction
protein 20884965
D019833 83787 ARMC10
PNAS-112
PNAS112
SVH
armadillo repeat containing 10 Genistein results in increased expression of ARMC10 protein increases expression
protein 20884965
D019833 51566 ARMCX3
ALEX3
dJ545K15.2
armadillo repeat containing, X-linked 3 ESR2 promotes the reaction [Genistein results in decreased expression of ARMCX3 protein] decreases expression
/ increases reaction
protein 20884965
D019833 51566 ARMCX3
ALEX3
dJ545K15.2
armadillo repeat containing, X-linked 3 Genistein results in decreased expression of ARMCX3 protein decreases expression
protein 20884965
D019833 405 ARNT
HIF-1-beta
HIF-1beta
HIF1-beta
HIF1B
HIF1BETA
TANGO
bHLHe2
aryl hydrocarbon receptor nuclear translocator Genistein affects the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]] affects binding
/ affects reaction
/ increases reaction
protein 10939628
D019833 405 ARNT
HIF-1-beta
HIF-1beta
HIF1-beta
HIF1B
HIF1BETA
TANGO
bHLHe2
aryl hydrocarbon receptor nuclear translocator Genistein affects the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]] affects binding
/ affects reaction
/ increases reaction
protein 10939628
D019833 414 ARSD
ASD
arylsulfatase D (EC:3.1.6.1) Genistein results in decreased expression of ARSD mRNA decreases expression
mRNA 19371625
D019833 427 ASAH1
AC
ACDase
ASAH
PHP
PHP32
SMAPME
N-acylsphingosine amidohydrolase (acid ceramidase) 1 (EC:3.5.1.23) Genistein results in decreased expression of ASAH1 mRNA decreases expression
mRNA 19371625
D019833 440 ASNS
TS11
asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) ESR1 promotes the reaction [Genistein results in increased expression of ASNS protein] increases expression
/ increases reaction
protein 20884965
D019833 440 ASNS
TS11
asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) Genistein results in increased expression of ASNS mRNA increases expression
mRNA 15757668
18444173
D019833 440 ASNS
TS11
asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) Genistein results in increased expression of ASNS protein increases expression
protein 20884965
D019833 259266 ASPM
ASP
Calmbp1
MCPH5
asp (abnormal spindle) homolog, microcephaly associated (Drosophila) Genistein affects the expression of ASPM mRNA affects expression
mRNA 18847459
D019833 259266 ASPM
ASP
Calmbp1
MCPH5
asp (abnormal spindle) homolog, microcephaly associated (Drosophila) Genistein results in increased expression of ASPM mRNA increases expression
mRNA 16474171
D019833 80150 ASRGL1
ALP
ALP1
CRASH
asparaginase like 1 (EC:3.5.1.1 3.4.19.5) Genistein results in increased expression of ASRGL1 mRNA increases expression
mRNA 19371625
D019833 445 ASS1
ASS
CTLN1
argininosuccinate synthase 1 (EC:6.3.4.5) Genistein results in increased expression of ASS1 mRNA increases expression
mRNA 15757668
D019833 29028 ATAD2
ANCCA
PRO2000
ATPase family, AAA domain containing 2 (EC:3.6.1.3) Genistein results in increased expression of ATAD2 mRNA increases expression
mRNA 16474171
D019833 467 ATF3
activating transcription factor 3 Genistein results in decreased expression of ATF3 mRNA decreases expression
mRNA 16474171
20884965
D019833 467 ATF3
activating transcription factor 3 Genistein results in increased expression of ATF3 mRNA increases expression
mRNA 21554132
D019833 467 ATF3
activating transcription factor 3 Genistein results in increased expression of ATF3 protein increases expression
protein 21554132
D019833 9474 ATG5
APG5
APG5-LIKE
APG5L
ASP
hAPG5
autophagy related 5 Genistein results in increased expression of ATG5 mRNA increases expression
mRNA 15256057
D019833 472 ATM
AT1
ATA
ATC
ATD
ATDC
ATE
TEL1
TELO1
ataxia telangiectasia mutated (EC:2.7.11.1) 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of ATM protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 472 ATM
AT1
ATA
ATC
ATD
ATDC
ATE
TEL1
TELO1
ataxia telangiectasia mutated (EC:2.7.11.1) 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of ATM protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 472 ATM
AT1
ATA
ATC
ATD
ATDC
ATE
TEL1
TELO1
ataxia telangiectasia mutated (EC:2.7.11.1) Caffeine inhibits the reaction [Genistein results in increased phosphorylation of ATM protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 472 ATM
AT1
ATA
ATC
ATD
ATDC
ATE
TEL1
TELO1
ataxia telangiectasia mutated (EC:2.7.11.1) Genistein results in increased phosphorylation of ATM protein increases phosphorylation
protein 19038232
D019833 472 ATM
AT1
ATA
ATC
ATD
ATDC
ATE
TEL1
TELO1
ataxia telangiectasia mutated (EC:2.7.11.1) U 0126 inhibits the reaction [Genistein results in increased phosphorylation of ATM protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 1822 ATN1
B37
D12S755E
DRPLA
HRS
NOD
atrophin 1 Genistein results in decreased expression of ATN1 mRNA decreases expression
mRNA 16705744
D019833 481 ATP1B1
ATP1B
ATPase, Na+/K+ transporting, beta 1 polypeptide Genistein results in decreased expression of ATP1B1 mRNA decreases expression
mRNA 16474171
D019833 514 ATP5E
ATPE
MC5DN3
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit (EC:3.6.3.14) Genistein results in increased expression of ATP5E mRNA increases expression
mRNA 16705744
D019833 23545 ATP6V0A2
A2
ARCL
ARCL2A
ATP6A2
ATP6N1D
J6B7
RTF
STV1
TJ6
TJ6M
TJ6S
VPH1
WSS
ATPase, H+ transporting, lysosomal V0 subunit a2 (EC:3.6.3.6) [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ATP6V0A2 mRNA affects cotreatment
/ decreases expression
mRNA 16963248
D019833 11273 ATXN2L
A2D
A2LG
A2LP
A2RP
ataxin 2-like Genistein results in decreased expression of ATXN2L mRNA decreases expression
mRNA 16705744
D019833 6790 AURKA
AIK
ARK1
AURA
AURORA2
BTAK
PPP1R47
STK15
STK6
STK7
aurora kinase A (EC:2.7.11.1) Genistein results in increased expression of AURKA mRNA increases expression
mRNA 16474171
D019833 9212 AURKB
AIK2
AIM-1
AIM1
ARK2
AurB
IPL1
PPP1R48
STK12
STK5
aurkb-sv1
aurkb-sv2
aurora kinase B (EC:2.7.11.1) Genistein results in increased expression of AURKB mRNA increases expression
mRNA 16474171
D019833 2683 B4GALT1
B4GAL-T1
CDG2D
GGTB2
GT1
GTB
beta4Gal-T1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (EC:2.4.1.22 2.4.1.90 2.4.1.38) Genistein results in increased expression of B4GALT1 mRNA increases expression
mRNA 14605097
D019833 9531 BAG3
BAG-3
BIS
CAIR-1
MFM6
BCL2-associated athanogene 3 Genistein results in increased expression of BAG3 mRNA increases expression
mRNA 23019147
D019833 9529 BAG5
BAG-5
BCL2-associated athanogene 5 ESR2 promotes the reaction [Genistein results in decreased expression of BAG5 protein] decreases expression
/ increases reaction
protein 20884965
D019833 9529 BAG5
BAG-5
BCL2-associated athanogene 5 Genistein results in decreased expression of BAG5 protein decreases expression
protein 20884965
D019833 10409 BASP1
CAP-23
CAP23
NAP-22
NAP22
brain abundant, membrane attached signal protein 1 Genistein results in decreased expression of BASP1 mRNA decreases expression
mRNA 16474171
D019833 581 BAX
BCL2L4
BCL2-associated X protein arsenic trioxide promotes the reaction [Genistein results in increased expression of BAX protein] increases expression
/ increases reaction
protein 20219070
D019833 581 BAX
BCL2L4
BCL2-associated X protein [Calcitriol co-treated with Genistein] results in increased expression of BAX mRNA affects cotreatment
/ increases expression
mRNA 15955619
D019833 581 BAX
BCL2L4
BCL2-associated X protein [Genistein co-treated with TNFSF10 protein] results in increased expression of BAX protein affects cotreatment
/ increases expression
protein 19497411
D019833 581 BAX
BCL2L4
BCL2-associated X protein Genistein promotes the reaction [arsenic trioxide results in increased expression of BAX protein] increases expression
/ increases reaction
protein 20219070
D019833 581 BAX
BCL2L4
BCL2-associated X protein Genistein results in increased expression of BAX protein increases expression
protein 20219070
D019833 11177 BAZ1A
ACF1
WALp1
WCRF180
hACF1
bromodomain adjacent to zinc finger domain, 1A [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of BAZ1A mRNA affects cotreatment
/ increases expression
mRNA 16963248
D019833 11176 BAZ2A
TIP5
WALp3
bromodomain adjacent to zinc finger domain, 2A Genistein results in decreased expression of BAZ2A mRNA decreases expression
mRNA 16705744
D019833 590 BCHE
CHE1
CHE2
E1
butyrylcholinesterase (EC:3.1.1.8) Genistein results in increased expression of BCHE mRNA increases expression
mRNA 15378649
D019833 593 BCKDHA
BCKDE1A
MSU
MSUD1
OVD1A
branched chain keto acid dehydrogenase E1, alpha polypeptide (EC:1.2.4.4) ESR1 promotes the reaction [Genistein results in decreased expression of BCKDHA protein] decreases expression
/ increases reaction
protein 20884965
D019833 593 BCKDHA
BCKDE1A
MSU
MSUD1
OVD1A
branched chain keto acid dehydrogenase E1, alpha polypeptide (EC:1.2.4.4) Genistein results in decreased expression of BCKDHA protein decreases expression
protein 20884965
D019833 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 arsenic trioxide promotes the reaction [Genistein results in decreased expression of BCL2 protein] decreases expression
/ increases reaction
protein 20219070
D019833 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 [Calcitriol co-treated with Genistein] results in decreased expression of BCL2 mRNA affects cotreatment
/ decreases expression
mRNA 15955619
D019833 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 [Genistein co-treated with arsenic trioxide] results in decreased expression of BCL2 protein affects cotreatment
/ decreases expression
protein 21078540
D019833 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 [Genistein co-treated with TNFSF10 protein] results in decreased expression of BCL2 protein affects cotreatment
/ decreases expression
protein 19497411
D019833 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Genistein inhibits the reaction [Paclitaxel results in increased phosphorylation of BCL2 protein] decreases reaction
/ increases phosphorylation
protein 15907805
D019833 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Genistein inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of BCL2 protein] decreases expression
/ decreases reaction
protein 15288519
D019833 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Genistein promotes the reaction [arsenic trioxide results in decreased expression of BCL2 protein] decreases expression
/ increases reaction
protein 20219070
D019833 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Genistein results in decreased expression of BCL2 protein decreases expression
protein 12791511
20219070
21078540
D019833 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 [Genistein co-treated with arsenic trioxide] results in decreased expression of BCL2L1 protein affects cotreatment
/ decreases expression
protein 21078540
D019833 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 Genistein promotes the reaction [arsenic trioxide results in decreased expression of BCL2L1 protein] decreases expression
/ increases reaction
protein 18546268
D019833 598 BCL2L1
BCL-XL/S
BCL2L
BCLX
BCLXL
BCLXS
Bcl-X
PPP1R52
bcl-xL
bcl-xS
BCL2-like 1 Genistein results in decreased expression of BCL2L1 protein decreases expression
protein 12791511
18546268
21078540
D019833 632 BGLAP
BGP
OC
OCN
bone gamma-carboxyglutamate (gla) protein [Genistein co-treated with ESR1 protein] results in increased expression of BGLAP mRNA affects cotreatment
/ increases expression
mRNA 19347870
D019833 632 BGLAP
BGP
OC
OCN
bone gamma-carboxyglutamate (gla) protein [Genistein co-treated with ESR2 protein] results in increased expression of BGLAP mRNA affects cotreatment
/ increases expression
mRNA 19347870
D019833 168620 BHLHA15
BHLHB8
MIST1
basic helix-loop-helix family, member a15 Genistein results in increased expression of BHLHA15 mRNA increases expression
mRNA 23019147
D019833 8553 BHLHE40
BHLHB2
DEC1
HLHB2
SHARP-2
STRA13
Stra14
basic helix-loop-helix family, member e40 Genistein results in decreased expression of BHLHE40 mRNA decreases expression
mRNA 16474171
D019833 636 BICD1
BICD
bicaudal D homolog 1 (Drosophila) Genistein results in increased expression of BICD1 mRNA increases expression
mRNA 19371625
D019833 637 BID
FP497
BH3 interacting domain death agonist [Genistein co-treated with TNFSF10 protein] results in increased cleavage of BID protein affects cotreatment
/ increases cleavage
protein 19497411
D019833 637 BID
FP497
BH3 interacting domain death agonist Genistein promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of BID protein] increases activity
/ increases cleavage
/ increases reaction
protein 18546268
D019833 637 BID
FP497
BH3 interacting domain death agonist Genistein results in increased cleavage of and results in increased activity of BID protein increases activity
/ increases cleavage
protein 18546268
D019833 332 BIRC5
API4
EPR-1
baculoviral IAP repeat containing 5 Genistein results in decreased expression of BIRC5 mRNA decreases expression
mRNA 16705744
D019833 332 BIRC5
API4
EPR-1
baculoviral IAP repeat containing 5 Genistein results in increased expression of BIRC5 mRNA increases expression
mRNA 16474171
D019833 90427 BMF
Bcl2 modifying factor Genistein results in decreased expression of BMF mRNA decreases expression
mRNA 23019147
D019833 662 BNIP1
NIP1
SEC20
TRG-8
BCL2/adenovirus E1B 19kDa interacting protein 1 Genistein results in increased expression of BNIP1 mRNA increases expression
mRNA 19371625
D019833 665 BNIP3L
BNIP3a
NIX
BCL2/adenovirus E1B 19kDa interacting protein 3-like Genistein results in decreased expression of BNIP3L mRNA decreases expression
mRNA 23019147
D019833 672 BRCA1
BRCAI
BRCC1
BROVCA1
IRIS
PNCA4
PPP1R53
PSCP
RNF53
breast cancer 1, early onset Genistein results in increased expression of BRCA1 mRNA increases expression
mRNA 16434996
17266178
D019833 672 BRCA1
BRCAI
BRCC1
BROVCA1
IRIS
PNCA4
PPP1R53
PSCP
RNF53
breast cancer 1, early onset Genistein results in increased expression of BRCA1 protein increases expression
protein 16434996
D019833 672 BRCA1
BRCAI
BRCC1
BROVCA1
IRIS
PNCA4
PPP1R53
PSCP
RNF53
breast cancer 1, early onset [indole-3-carbinol co-treated with Genistein] results in increased expression of BRCA1 protein affects cotreatment
/ increases expression
protein 16434996
D019833 675 BRCA2
BRCC2
BROVCA2
FACD
FAD
FAD1
FANCB
FANCD
FANCD1
GLM3
PNCA2
breast cancer 2, early onset Genistein results in increased expression of BRCA2 mRNA increases expression
mRNA 16434996
D019833 675 BRCA2
BRCC2
BROVCA2
FACD
FAD
FAD1
FANCB
FANCD
FANCD1
GLM3
PNCA2
breast cancer 2, early onset Genistein results in increased expression of BRCA2 protein increases expression
protein 16434996
D019833 675 BRCA2
BRCC2
BROVCA2
FACD
FAD
FAD1
FANCB
FANCD
FANCD1
GLM3
PNCA2
breast cancer 2, early onset [indole-3-carbinol co-treated with Genistein] results in increased expression of BRCA2 protein affects cotreatment
/ increases expression
protein 16434996
D019833 55845 BRK1
C3orf10
MDS027
hHBrk1
BRICK1, SCAR/WAVE actin-nucleating complex subunit Genistein results in increased expression of BRK1 mRNA increases expression
mRNA 16705744
D019833 428592 Genistein results in increased expression of BRP44L mRNA increases expression
mRNA 20884965
D019833 103993 [Genistein co-treated with ESR1] results in increased expression of BSP mRNA affects cotreatment
/ increases expression
mRNA 19347870
D019833 103993 [Genistein co-treated with ESR2] results in increased expression of BSP mRNA affects cotreatment
/ increases expression
mRNA 19347870
D019833 694 BTG1
B-cell translocation gene 1, anti-proliferative Genistein results in decreased expression of BTG1 mRNA decreases expression
mRNA 16474171
D019833 7832 BTG2
PC3
TIS21
BTG family, member 2 Genistein results in decreased expression of BTG2 mRNA decreases expression
mRNA 16705744
D019833 10950 BTG3
ANA
TOB5
TOB55
TOFA
BTG family, member 3 Genistein results in decreased methylation of BTG3 promoter decreases methylation
promoter 19221000
D019833 10950 BTG3
ANA
TOB5
TOB55
TOFA
BTG family, member 3 Genistein results in increased expression of BTG3 mRNA increases expression
mRNA 19221000
D019833 699 BUB1
BUB1A
BUB1L
hBUB1
BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1) Genistein affects the expression of BUB1 mRNA affects expression
mRNA 18847459
D019833 701 BUB1B
BUB1beta
BUBR1
Bub1A
MAD3L
MVA1
SSK1
hBUBR1
BUB1 mitotic checkpoint serine/threonine kinase B (EC:2.7.11.1) Genistein affects the expression of BUB1B mRNA affects expression
mRNA 18847459
D019833 701 BUB1B
BUB1beta
BUBR1
Bub1A
MAD3L
MVA1
SSK1
hBUBR1
BUB1 mitotic checkpoint serine/threonine kinase B (EC:2.7.11.1) Genistein results in increased expression of BUB1B mRNA increases expression
mRNA 16474171
D019833 56652 C10orf2
ATXN8
IOSCA
MTDPS7
PEO
PEO1
PEOA3
SANDO
SCA8
TWINL
chromosome 10 open reading frame 2 (EC:3.6.4.12) Genistein results in increased expression of C10ORF2 mRNA increases expression
mRNA 23019147
D019833 219833 C11orf45
chromosome 11 open reading frame 45 Genistein results in increased expression of C11ORF45 mRNA increases expression
mRNA 23019147
D019833 84419 C15orf48
FOAP-11
NMES1
chromosome 15 open reading frame 48 Genistein results in decreased expression of C15ORF48 mRNA decreases expression
mRNA 20884965
D019833 79415 C17orf62
chromosome 17 open reading frame 62 Genistein results in increased expression of C17ORF62 mRNA increases expression
mRNA 23019147
D019833 388722 C1orf53
chromosome 1 open reading frame 53 Genistein results in decreased expression of C1ORF53 mRNA decreases expression
mRNA 23019147
D019833 79680 C22orf29
BOP
chromosome 22 open reading frame 29 Genistein results in increased expression of C22ORF29 mRNA increases expression
mRNA 19371625
D019833 79919 C2orf54
chromosome 2 open reading frame 54 Genistein results in increased expression of C2ORF54 mRNA increases expression
mRNA 23019147
D019833 718 C3
AHUS5
ARMD9
ASP
C3a
C3b
CPAMD1
complement component 3 (EC:3.4.21.43) Genistein results in increased expression of C3 mRNA increases expression
mRNA 20884965
D019833 100495920 Genistein results in increased expression of C3ORF21 mRNA increases expression
mRNA 23019147
D019833 50854 C6orf48
D6S57
G8
chromosome 6 open reading frame 48 Genistein results in decreased expression of C6ORF48 mRNA decreases expression
mRNA 19371625
D019833 771 CA12
CAXII
HsT18816
carbonic anhydrase XII (EC:4.2.1.1) Genistein results in increased expression of CA12 mRNA increases expression
mRNA 16474171
23019147
D019833 760 CA2
CA-II
CAC
CAII
Car2
carbonic anhydrase II (EC:4.2.1.1) Genistein results in increased expression of CA2 mRNA increases expression
mRNA 19371625
23019147
D019833 91768 CABLES1
CABL1
CABLES
HsT2563
IK3-1
Cdk5 and Abl enzyme substrate 1 Genistein results in increased expression of CABLES1 mRNA increases expression
mRNA 19371625
23019147
D019833 8911 CACNA1I
Cav3.3
ca(v)3.3
calcium channel, voltage-dependent, T type, alpha 1I subunit Genistein results in increased expression of CACNA1I mRNA increases expression
mRNA 23019147
D019833 55450 CAMK2N1
PRO1489
RP11-401M16.1
calcium/calmodulin-dependent protein kinase II inhibitor 1 Genistein results in decreased expression of CAMK2N1 mRNA decreases expression
mRNA 16474171
D019833 10645 CAMKK2
CAMKK
CAMKKB
calcium/calmodulin-dependent protein kinase kinase 2, beta (EC:2.7.11.17) Genistein results in decreased expression of CAMKK2 mRNA decreases expression
mRNA 15378649
D019833 821 CANX
CNX
IP90
P90
calnexin ESR2 promotes the reaction [Genistein results in increased expression of CANX protein] increases expression
/ increases reaction
protein 20884965
D019833 821 CANX
CNX
IP90
P90
calnexin Genistein results in increased expression of CANX protein increases expression
protein 20884965
D019833 823 CAPN1
CANP
CANP1
CANPL1
muCANP
muCL
calpain 1, (mu/I) large subunit (EC:3.4.22.52) Genistein results in decreased expression of CAPN1 mRNA decreases expression
mRNA 16705744
D019833 6650 CAPN15
SOLH
calpain 15 Genistein results in increased expression of CAPN15 mRNA increases expression
mRNA 23019147
D019833 10753 CAPN9
GC36
nCL-4
calpain 9 (EC:3.4.22.-) Genistein results in increased expression of CAPN9 mRNA increases expression
mRNA 19371625
D019833 828 CAPS
CAPS1
calcyphosine Genistein results in increased expression of CAPS mRNA increases expression
mRNA 23019147
D019833 29775 CARD10
BIMP1
CARMA3
caspase recruitment domain family, member 10 Genistein results in increased expression of CARD10 mRNA increases expression
mRNA 23019147
D019833 833 CARS
CARS1
CYSRS
MGC:11246
cysteinyl-tRNA synthetase (EC:6.1.1.16) Genistein results in increased expression of CARS mRNA increases expression
mRNA 19371625
D019833 843 CASP10
ALPS2
FLICE2
MCH4
caspase 10, apoptosis-related cysteine peptidase (EC:3.4.22.63) [Genistein co-treated with trichostatin A] results in increased activity of CASP10 protein affects cotreatment
/ increases activity
protein 22626855
D019833 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) arsenic trioxide promotes the reaction [Genistein results in increased activity of CASP3 protein] increases activity
/ increases reaction
protein 20219070
D019833 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) [Genistein co-treated with arsenic trioxide] results in decreased expression of CASP3 protein affects cotreatment
/ decreases expression
protein 21078540
D019833 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) [Genistein co-treated with TNFSF10 protein] results in increased activity of CASP3 protein affects cotreatment
/ increases activity
protein 19497411
D019833 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) [Genistein co-treated with trichostatin A] results in increased activity of CASP3 protein affects cotreatment
/ increases activity
protein 22626855
D019833 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Genistein inhibits the reaction [benzo(e)pyrene results in increased activity of CASP3 protein] decreases reaction
/ increases activity
protein 19959636
D019833 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Genistein promotes the reaction [arsenic trioxide results in increased activity of CASP3 protein] increases activity
/ increases reaction
protein 18546268
20219070
D019833 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Genistein results in decreased expression of CASP3 protein decreases expression
protein 21078540
D019833 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Genistein results in increased activity of CASP3 protein increases activity
protein 12791511
16924424
17132221
20219070
D019833 840 CASP7
CASP-7
CMH-1
ICE-LAP3
LICE2
MCH3
caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) Genistein inhibits the reaction [benzo(e)pyrene results in increased activity of CASP7 protein] decreases reaction
/ increases activity
protein 19959636
D019833 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) [Genistein co-treated with TNFSF10 protein] results in increased activity of CASP8 protein affects cotreatment
/ increases activity
protein 19497411
D019833 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) Genistein promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of CASP8 protein] increases activity
/ increases cleavage
/ increases reaction
protein 18546268
D019833 9994 CASP8AP2
CED-4
FLASH
RIP25
caspase 8 associated protein 2 Genistein results in increased expression of CASP8AP2 mRNA increases expression
mRNA 15256057
D019833 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) [Genistein co-treated with TNFSF10 protein] results in increased activity of CASP9 protein affects cotreatment
/ increases activity
protein 19497411
D019833 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) Genistein inhibits the reaction [benzo(e)pyrene results in increased activity of CASP9 protein] decreases reaction
/ increases activity
protein 19959636
D019833 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) Genistein promotes the reaction [arsenic trioxide results in increased activity of CASP9 protein] increases activity
/ increases reaction
protein 20219070
D019833 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) Genistein results in increased activity of CASP9 protein increases activity
protein 20219070
D019833 863 CBFA2T3
ETO2
MTG16
MTGR2
ZMYND4
core-binding factor, runt domain, alpha subunit 2; translocated to, 3 Genistein results in increased expression of CBFA2T3 mRNA increases expression
mRNA 19371625
23019147
D019833 873 CBR1
CBR
SDR21C1
hCBR1
carbonyl reductase 1 (EC:1.1.1.189 1.1.1.197 1.1.1.184) Genistein results in increased expression of CBR1 mRNA increases expression
mRNA 16705744
D019833 23468 CBX5
HP1
HP1A
chromobox homolog 5 ESR2 promotes the reaction [Genistein results in increased expression of CBX5 protein] increases expression
/ increases reaction
protein 20884965
D019833 23468 CBX5
HP1
HP1A
chromobox homolog 5 Genistein results in increased expression of CBX5 protein increases expression
protein 20884965
D019833 23466 CBX6
chromobox homolog 6 Genistein results in decreased expression of CBX6 mRNA decreases expression
mRNA 16705744
D019833 23466 CBX6
chromobox homolog 6 Genistein results in increased expression of CBX6 mRNA increases expression
mRNA 20884965
D019833 55246 CCDC25
coiled-coil domain containing 25 ESR1 promotes the reaction [Genistein results in increased expression of CCDC25 protein] increases expression
/ increases reaction
protein 20884965
D019833 55246 CCDC25
coiled-coil domain containing 25 Genistein results in increased expression of CCDC25 protein increases expression
protein 20884965
D019833 26112 CCDC69
coiled-coil domain containing 69 Genistein results in increased expression of CCDC69 mRNA increases expression
mRNA 20884965
D019833 79080 CCDC86
coiled-coil domain containing 86 Genistein results in increased expression of CCDC86 mRNA increases expression
mRNA 23019147
D019833 6347 CCL2
GDCF-2
HC11
HSMCR30
MCAF
MCP-1
MCP1
SCYA2
SMC-CF
chemokine (C-C motif) ligand 2 Genistein inhibits the reaction [LEP protein results in increased expression of CCL2] decreases reaction
/ increases expression
11342529
D019833 6347 CCL2
GDCF-2
HC11
HSMCR30
MCAF
MCP-1
MCP1
SCYA2
SMC-CF
chemokine (C-C motif) ligand 2 Genistein results in decreased secretion of CCL2 protein decreases secretion
protein 20816778
D019833 6351 CCL4
ACT2
AT744.1
G-26
HC21
LAG-1
LAG1
MIP-1-beta
MIP1B
MIP1B1
SCYA2
SCYA4
chemokine (C-C motif) ligand 4 Genistein results in decreased expression of CCL4 mRNA decreases expression
mRNA 15256057
D019833 890 CCNA2
CCN1
CCNA
cyclin A2 Genistein affects the expression of CCNA2 mRNA affects expression
mRNA 18847459
D019833 890 CCNA2
CCN1
CCNA
cyclin A2 Genistein results in decreased expression of CCNA2 decreases expression
21161820
D019833 890 CCNA2
CCN1
CCNA
cyclin A2 Genistein results in decreased expression of CCNA2 mRNA decreases expression
mRNA 16865672
D019833 890 CCNA2
CCN1
CCNA
cyclin A2 Genistein results in increased expression of CCNA2 mRNA increases expression
mRNA 16474171
D019833 891 CCNB1
CCNB
cyclin B1 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of CCNB1 protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 891 CCNB1
CCNB
cyclin B1 Caffeine inhibits the reaction [Genistein results in increased expression of CCNB1 protein] decreases reaction
/ increases expression
protein 19038232
D019833 891 CCNB1
CCNB
cyclin B1 Genistein affects the expression of CCNB1 mRNA affects expression
mRNA 18847459
D019833 891 CCNB1
CCNB
cyclin B1 Genistein affects the expression of CCNB1 protein affects expression
protein 10601582
D019833 891 CCNB1
CCNB
cyclin B1 Genistein results in increased expression of CCNB1 protein increases expression
protein 19038232
D019833 891 CCNB1
CCNB
cyclin B1 U 0126 inhibits the reaction [Genistein results in increased phosphorylation of CCNB1 protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 9133 CCNB2
HsT17299
cyclin B2 Genistein affects the expression of CCNB2 mRNA affects expression
mRNA 18847459
D019833 9133 CCNB2
HsT17299
cyclin B2 Genistein results in decreased expression of CCNB2 mRNA decreases expression
mRNA 16865672
D019833 9133 CCNB2
HsT17299
cyclin B2 Genistein results in increased expression of CCNB2 mRNA increases expression
mRNA 16474171
D019833 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 [Calcitriol co-treated with Genistein] results in decreased expression of CCND1 mRNA affects cotreatment
/ decreases expression
mRNA 15955619
D019833 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 [Genistein co-treated with arsenic trioxide] results in decreased expression of CCND1 protein affects cotreatment
/ decreases expression
protein 21078540
D019833 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Genistein inhibits the reaction [bisphenol A results in increased expression of CCND1] decreases reaction
/ increases expression
23229410
D019833 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Genistein inhibits the reaction [Estradiol results in increased expression of CCND1] decreases reaction
/ increases expression
23229410
D019833 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Genistein results in decreased expression of CCND1 mRNA decreases expression
mRNA 15955619
D019833 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Genistein results in decreased expression of CCND1 protein decreases expression
protein 21078540
D019833 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Genistein results in increased expression of CCND1 mRNA increases expression
mRNA 17266178
19800779
23524099
D019833 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 Genistein results in increased expression of CCND1 protein increases expression
protein 15829497
17051425
D019833 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 lycopene inhibits the reaction [Genistein results in increased expression of CCND1 protein] decreases reaction
/ increases expression
protein 17051425
D019833 894 CCND2
KIAK0002
cyclin D2 Genistein results in increased expression of CCND2 mRNA increases expression
mRNA 23019147
D019833 960 CD44
CDW44
CSPG8
ECMR-III
HCELL
HUTCH-I
IN
LHR
MC56
MDU2
MDU3
MIC4
Pgp1
CD44 molecule (Indian blood group) Genistein results in decreased expression of CD44 mRNA decreases expression
mRNA 16705744
D019833 960 CD44
CDW44
CSPG8
ECMR-III
HCELL
HUTCH-I
IN
LHR
MC56
MDU2
MDU3
MIC4
Pgp1
CD44 molecule (Indian blood group) Genistein results in increased expression of CD44 mRNA increases expression
mRNA 20706672
D019833 965 CD58
LFA-3
LFA3
ag3
CD58 molecule Genistein results in increased expression of CD58 mRNA increases expression
mRNA 16705744
D019833 3732 CD82
4F9
C33
GR15
IA4
KAI1
R2
SAR2
ST6
TSPAN27
CD82 molecule Genistein results in increased expression of CD82 mRNA increases expression
mRNA 18847459
D019833 928 CD9
BTCC-1
DRAP-27
MIC3
MRP-1
TSPAN-29
TSPAN29
CD9 molecule ESR2 promotes the reaction [Genistein results in increased expression of CD9 protein] increases expression
/ increases reaction
protein 20884965
D019833 928 CD9
BTCC-1
DRAP-27
MIC3
MRP-1
TSPAN-29
TSPAN29
CD9 molecule Genistein results in increased expression of CD9 protein increases expression
protein 20884965
D019833 976 CD97
TM7LN1
CD97 molecule Genistein results in decreased expression of CD97 mRNA decreases expression
mRNA 21738342
D019833 991 CDC20
CDC20A
bA276H19.3
p55CDC
cell division cycle 20 Genistein affects the expression of CDC20 mRNA affects expression
mRNA 18847459
D019833 991 CDC20
CDC20A
bA276H19.3
p55CDC
cell division cycle 20 Genistein results in increased expression of CDC20 mRNA increases expression
mRNA 16474171
D019833 994 CDC25B
cell division cycle 25B (EC:3.1.3.48) Genistein results in decreased expression of CDC25B mRNA decreases expression
mRNA 16865672
D019833 995 CDC25C
CDC25
PPP1R60
cell division cycle 25C (EC:3.1.3.48) Genistein results in decreased expression of CDC25C mRNA decreases expression
mRNA 16865672
D019833 11135 CDC42EP1
BORG5
CEP1
MSE55
CDC42 effector protein (Rho GTPase binding) 1 Genistein results in increased expression of CDC42EP1 mRNA increases expression
mRNA 23019147
D019833 8318 CDC45
CDC45L
CDC45L2
PORC-PI-1
cell division cycle 45 Genistein results in increased expression of CDC45 mRNA increases expression
mRNA 16474171
D019833 990 CDC6
CDC18L
HsCDC18
HsCDC6
cell division cycle 6 Genistein results in increased expression of CDC6 mRNA increases expression
mRNA 16474171
D019833 113130 CDCA5
SORORIN
cell division cycle associated 5 Genistein affects the expression of CDCA5 mRNA affects expression
mRNA 18847459
D019833 1000 CDH2
CD325
CDHN
CDw325
NCAD
cadherin 2, type 1, N-cadherin (neuronal) Genistein results in increased expression of CDH2 protein increases expression
protein 16149052
D019833 983 CDK1
CDC2
CDC28A
P34CDC2
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of CDK1 protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 983 CDK1
CDC2
CDC28A
P34CDC2
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) Caffeine inhibits the reaction [Genistein results in increased phosphorylation of CDK1 protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 983 CDK1
CDC2
CDC28A
P34CDC2
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) Genistein affects the expression of CDK1 mRNA affects expression
mRNA 18847459
D019833 983 CDK1
CDC2
CDC28A
P34CDC2
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) Genistein results in decreased phosphorylation of CDK1 protein decreases phosphorylation
protein 10601582
D019833 983 CDK1
CDC2
CDC28A
P34CDC2
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) Genistein results in increased expression of CDK1 mRNA increases expression
mRNA 16474171
D019833 983 CDK1
CDC2
CDC28A
P34CDC2
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) Genistein results in increased phosphorylation of and results in decreased activity of CDK1 protein decreases activity
/ increases phosphorylation
protein 11322924
D019833 983 CDK1
CDC2
CDC28A
P34CDC2
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) Genistein results in increased phosphorylation of CDK1 protein increases phosphorylation
protein 19038232
D019833 983 CDK1
CDC2
CDC28A
P34CDC2
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) U 0126 inhibits the reaction [Genistein results in increased phosphorylation of CDK1 protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 1017 CDK2
p33(CDK2)
cyclin-dependent kinase 2 (EC:2.7.11.22) Genistein results in increased expression of CDK2 mRNA increases expression
mRNA 16474171
D019833 10263 CDK2AP2
DOC-1R
p14
cyclin-dependent kinase 2 associated protein 2 Genistein results in decreased expression of CDK2AP2 mRNA decreases expression
mRNA 16474171
D019833 1019 CDK4
CMM3
PSK-J3
cyclin-dependent kinase 4 (EC:2.7.11.22) Genistein results in decreased activity of CDK4 protein decreases activity
protein 21161820
D019833 1020 CDK5
PSSALRE
cyclin-dependent kinase 5 (EC:2.7.11.22) Genistein results in increased expression of CDK5 protein increases expression
protein 16149052
D019833 1024 CDK8
K35
cyclin-dependent kinase 8 (EC:2.7.11.23 2.7.11.22) Genistein results in increased expression of CDK8 mRNA increases expression
mRNA 15378649
D019833 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of CDKN1A protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) [Calcitriol co-treated with Genistein] results in increased expression of CDKN1A mRNA affects cotreatment
/ increases expression
mRNA 15955619
D019833 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) ESR2 affects the reaction [Genistein results in increased expression of CDKN1A] affects reaction
/ increases expression
21161820
D019833 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) [Fluorouracil co-treated with Genistein] results in increased expression of CDKN1A mRNA affects cotreatment
/ increases expression
mRNA 15896711
D019833 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Genistein inhibits the reaction [bisphenol A results in decreased expression of CDKN1A] decreases expression
/ decreases reaction
23229410
D019833 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Genistein inhibits the reaction [Estradiol results in decreased expression of CDKN1A] decreases expression
/ decreases reaction
23229410
D019833 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Genistein results in decreased expression of CDKN1A mRNA decreases expression
mRNA 16474171
D019833 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Genistein results in decreased expression of CDKN1A protein decreases expression
protein 17051425
D019833 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Genistein results in increased expression of CDKN1A increases expression
21161820
D019833 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Genistein results in increased expression of CDKN1A mRNA increases expression
mRNA 16865672
D019833 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Genistein results in increased expression of CDKN1A protein increases expression
protein 11322924
11790449
12111696
16149052
19038232
D019833 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) U 0126 inhibits the reaction [Genistein results in increased phosphorylation of CDKN1A protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 1027 CDKN1B
CDKN4
KIP1
MEN1B
MEN4
P27KIP1
cyclin-dependent kinase inhibitor 1B (p27, Kip1) Genistein results in increased expression of CDKN1B protein increases expression
protein 15829497
D019833 1028 CDKN1C
BWCR
BWS
KIP2
WBS
p57
p57Kip2
cyclin-dependent kinase inhibitor 1C (p57, Kip2) Genistein results in decreased expression of CDKN1C mRNA decreases expression
mRNA 23019147
D019833 1031 CDKN2C
INK4C
p18
p18-INK4C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) Genistein results in decreased expression of CDKN2C mRNA decreases expression
mRNA 16474171
D019833 1033 CDKN3
CDI1
CIP2
KAP
KAP1
cyclin-dependent kinase inhibitor 3 (EC:3.1.3.16 3.1.3.48) Genistein results in decreased expression of CDKN3 mRNA decreases expression
mRNA 16474171
D019833 81620 CDT1
DUP
RIS2
chromatin licensing and DNA replication factor 1 Genistein results in increased expression of CDT1 mRNA increases expression
mRNA 16474171
D019833 1051 CEBPB
C/EBP-beta
CRP2
IL6DBP
LAP
LIP
NF-IL6
TCF5
CCAAT/enhancer binding protein (C/EBP), beta Genistein results in increased expression of CEBPB mRNA increases expression
mRNA 19371625
D019833 1052 CEBPD
C/EBP-delta
CELF
CRP3
NF-IL6-beta
CCAAT/enhancer binding protein (C/EBP), delta Genistein results in decreased expression of CEBPD mRNA decreases expression
mRNA 16474171
D019833 1052 CEBPD
C/EBP-delta
CELF
CRP3
NF-IL6-beta
CCAAT/enhancer binding protein (C/EBP), delta Genistein results in increased expression of CEBPD mRNA increases expression
mRNA 19371625
D019833 1952 CELSR2
CDHF10
EGFL2
Flamingo1
MEGF3
cadherin, EGF LAG seven-pass G-type receptor 2 Genistein results in increased expression of CELSR2 mRNA increases expression
mRNA 20884965
D019833 1058 CENPA
CENP-A
CenH3
centromere protein A Genistein results in increased expression of CENPA mRNA increases expression
mRNA 16474171
D019833 1062 CENPE
CENP-E
KIF10
PPP1R61
centromere protein E, 312kDa Genistein affects the expression of CENPE mRNA affects expression
mRNA 18847459
D019833 1063 CENPF
CENF
PRO1779
hcp-1
centromere protein F, 350/400kDa Genistein affects the expression of CENPF mRNA affects expression
mRNA 18847459
D019833 1063 CENPF
CENF
PRO1779
hcp-1
centromere protein F, 350/400kDa Genistein results in increased expression of CENPF mRNA increases expression
mRNA 16474171
D019833 55835 CENPJ
BM032
CENP-J
CPAP
LAP
LIP1
MCPH6
SASS4
SCKL4
Sas-4
centromere protein J Genistein results in increased expression of CENPJ mRNA increases expression
mRNA 16474171
D019833 55839 CENPN
BM039
C16orf60
CENP-N
ICEN32
centromere protein N Genistein results in increased expression of CENPN mRNA increases expression
mRNA 16474171
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides] affects cotreatment
/ decreases reaction
/ increases activity
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]] affects cotreatment
/ decreases reaction
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) 5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]] affects cotreatment
/ decreases reaction
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) 6-hydroxy-10-chlorobenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]] affects cotreatment
/ decreases reaction
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] affects cotreatment
/ decreases reaction
/ increases reaction
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] affects cotreatment
/ decreases reaction
/ increases reaction
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) Brefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] affects cotreatment
/ decreases reaction
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) Brefeldin A inhibits the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] affects cotreatment
/ decreases reaction
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides] affects cotreatment
/ decreases reaction
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) [Colforsin co-treated with Genistein] results in increased activity of CFTR protein affects cotreatment
/ increases activity
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) [[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides affects cotreatment
/ increases activity
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) fenamic acid inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides] affects cotreatment
/ decreases reaction
/ increases activity
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) geldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] affects cotreatment
/ decreases reaction
/ increases reaction
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) geldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] affects cotreatment
/ decreases reaction
/ increases reaction
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) Genistein affects the localization of CFTR protein mutant form affects localization
protein 15191910
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) Genistein promotes the reaction [CFTR protein affects the export of Chlorides] affects export
/ increases reaction
protein 12914781
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) Genistein results in increased activity of CFTR protein increases activity
protein 12914781
15163550
15880796
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) Genistein results in increased activity of CFTR protein mutant form increases activity
protein 15163550
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) Glyburide inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides] affects cotreatment
/ decreases reaction
/ increases activity
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]] affects cotreatment
/ decreases reaction
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) Thapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] affects cotreatment
/ decreases reaction
/ increases reaction
/ increases transport
protein 18230692
D019833 1080 CFTR
ABC35
ABCC7
CF
CFTR/MRP
MRP7
TNR-CFTR
dJ760C5.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) Thapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] affects cotreatment
/ decreases reaction
/ increases reaction
/ increases transport
protein 18230692
D019833 494143 CHAC2
ChaC, cation transport regulator homolog 2 (E. coli) Genistein results in increased expression of CHAC2 mRNA increases expression
mRNA 19371625
D019833 10036 CHAF1A
CAF-1
CAF1
CAF1B
CAF1P150
P150
chromatin assembly factor 1, subunit A (p150) Genistein results in decreased expression of CHAF1A mRNA decreases expression
mRNA 16705744
D019833 118487 CHCHD1
C10orf34
C2360
MRP-S37
coiled-coil-helix-coiled-coil-helix domain containing 1 ESR1 promotes the reaction [Genistein results in decreased expression of CHCHD1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 118487 CHCHD1
C10orf34
C2360
MRP-S37
coiled-coil-helix-coiled-coil-helix domain containing 1 Genistein results in decreased expression of CHCHD1 protein decreases expression
protein 20884965
D019833 1111 CHEK1
CHK1
checkpoint kinase 1 (EC:2.7.11.1) Genistein results in increased expression of CHEK1 mRNA increases expression
mRNA 16474171
D019833 11200 CHEK2
CDS1
CHK2
HuCds1
LFS2
PP1425
RAD53
hCds1
checkpoint kinase 2 (EC:2.7.11.1) 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of CHEK2 protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 11200 CHEK2
CDS1
CHK2
HuCds1
LFS2
PP1425
RAD53
hCds1
checkpoint kinase 2 (EC:2.7.11.1) Caffeine inhibits the reaction [Genistein results in increased phosphorylation of CHEK2 protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 11200 CHEK2
CDS1
CHK2
HuCds1
LFS2
PP1425
RAD53
hCds1
checkpoint kinase 2 (EC:2.7.11.1) Genistein results in increased phosphorylation of CHEK2 protein increases phosphorylation
protein 19038232
D019833 11200 CHEK2
CDS1
CHK2
HuCds1
LFS2
PP1425
RAD53
hCds1
checkpoint kinase 2 (EC:2.7.11.1) U 0126 inhibits the reaction [Genistein results in increased phosphorylation of CHEK2 protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 25978 CHMP2B
ALS17
CHMP2.5
DMT1
VPS2-2
VPS2B
charged multivesicular body protein 2B ESR1 promotes the reaction [Genistein results in decreased expression of CHMP2B protein] decreases expression
/ increases reaction
protein 20884965
D019833 25978 CHMP2B
ALS17
CHMP2.5
DMT1
VPS2-2
VPS2B
charged multivesicular body protein 2B Genistein results in decreased expression of CHMP2B protein decreases expression
protein 20884965
D019833 1124 CHN2
ARHGAP3
BCH
CHN2-3
RHOGAP3
chimerin 2 Genistein results in decreased expression of CHN2 mRNA decreases expression
mRNA 23019147
D019833 22856 CHSY1
CHSY
CSS1
ChSy-1
TPBS
chondroitin sulfate synthase 1 (EC:2.4.1.175 2.4.1.226) Genistein results in increased expression of CHSY1 mRNA increases expression
mRNA 16474171
D019833 8483 CILP
CILP-1
HsT18872
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase Genistein results in increased expression of CILP mRNA increases expression
mRNA 19371625
23019147
D019833 1154 CISH
BACTS2
CIS
CIS-1
G18
SOCS
cytokine inducible SH2-containing protein Genistein results in increased expression of CISH mRNA increases expression
mRNA 23019147
D019833 11113 CIT
CRIK
STK21
citron (rho-interacting, serine/threonine kinase 21) (EC:2.7.11.1) Genistein affects the expression of CIT mRNA affects expression
mRNA 18847459
D019833 10370 CITED2
ASD8
MRG-1
MRG1
P35SRJ
VSD2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 Genistein results in increased expression of CITED2 mRNA increases expression
mRNA 11331657
D019833 1152 CKB
B-CK
CKBB
creatine kinase, brain (EC:2.7.3.2) Genistein results in increased activity of CKB protein increases activity
protein 16621514
D019833 1152 CKB
B-CK
CKBB
creatine kinase, brain (EC:2.7.3.2) Genistein results in increased expression of CKB mRNA increases expression
mRNA 23019147
D019833 1152 CKB
B-CK
CKBB
creatine kinase, brain (EC:2.7.3.2) Glucose inhibits the reaction [Genistein results in increased activity of CKB protein] decreases reaction
/ increases activity
protein 16621514
D019833 1163 CKS1B
CKS1
PNAS-16
PNAS-18
ckshs1
CDC28 protein kinase regulatory subunit 1B Genistein results in increased expression of CKS1B mRNA increases expression
mRNA 16474171
D019833 9076 CLDN1
CLD1
ILVASC
SEMP1
claudin 1 ESR2 promotes the reaction [Genistein results in increased expression of CLDN1 protein] increases expression
/ increases reaction
protein 20884965
D019833 9076 CLDN1
CLD1
ILVASC
SEMP1
claudin 1 Genistein results in increased expression of CLDN1 mRNA increases expression
mRNA 18847459
D019833 9076 CLDN1
CLD1
ILVASC
SEMP1
claudin 1 Genistein results in increased expression of CLDN1 protein increases expression
protein 20884965
D019833 10686 CLDN16
HOMG3
PCLN1
claudin 16 Genistein results in decreased expression of CLDN16 mRNA decreases expression
mRNA 23019147
D019833 1364 CLDN4
CPE-R
CPER
CPETR
CPETR1
WBSCR8
hCPE-R
claudin 4 Genistein results in decreased expression of CLDN4 mRNA decreases expression
mRNA 16474171
D019833 54102 CLIC6
CLIC1L
chloride intracellular channel 6 Genistein results in increased expression of CLIC6 mRNA increases expression
mRNA 16474171
D019833 1209 CLPTM1
cleft lip and palate associated transmembrane protein 1 Genistein results in decreased expression of CLPTM1 mRNA decreases expression
mRNA 16705744
D019833 23277 CLUH
CLU1
KIAA0664
clustered mitochondria (cluA/CLU1) homolog Genistein results in increased expression of CLUH mRNA increases expression
mRNA 23019147
D019833 112616 CMTM7
CKLFSF7
CKLF-like MARVEL transmembrane domain containing 7 Genistein results in increased expression of CMTM7 mRNA increases expression
mRNA 23019147
D019833 84518 CNFN
PLAC8L2
cornifelin Genistein results in decreased expression of CNFN mRNA decreases expression
mRNA 19371625
D019833 1264 CNN1
SMCC
Sm-Calp
calponin 1, basic, smooth muscle Genistein results in decreased expression of CNN1 mRNA decreases expression
mRNA 20884965
D019833 1265 CNN2
calponin 2 ESR2 promotes the reaction [Genistein results in decreased expression of CNN2 protein] decreases expression
/ increases reaction
protein 20884965
D019833 1265 CNN2
calponin 2 Genistein results in decreased expression of CNN2 protein decreases expression
protein 20884965
D019833 10330 CNPY2
HP10390
MSAP
TMEM4
ZSIG9
canopy FGF signaling regulator 2 ESR2 promotes the reaction [Genistein results in increased expression of CNPY2 protein] increases expression
/ increases reaction
protein 20884965
D019833 10330 CNPY2
HP10390
MSAP
TMEM4
ZSIG9
canopy FGF signaling regulator 2 Genistein results in increased expression of CNPY2 protein increases expression
protein 20884965
D019833 1303 COL12A1
BA209D8.1
COL12A1L
DJ234P15.1
collagen, type XII, alpha 1 Genistein results in increased expression of COL12A1 mRNA increases expression
mRNA 16474171
D019833 80781 COL18A1
KNO
KNO1
KS
collagen, type XVIII, alpha 1 Genistein results in decreased expression of COL18A1 mRNA decreases expression
mRNA 16705744
D019833 80781 COL18A1
KNO
KNO1
KS
collagen, type XVIII, alpha 1 Genistein results in increased expression of COL18A1 mRNA increases expression
mRNA 20884965
D019833 1291 COL6A1
OPLL
collagen, type VI, alpha 1 Genistein results in increased expression of COL6A1 mRNA increases expression
mRNA 23019147
D019833 1312 COMT
catechol-O-methyltransferase (EC:2.1.1.6) fulvestrant inhibits the reaction [Genistein results in decreased expression of COMT mRNA] decreases expression
/ decreases reaction
mRNA 18192686
18497090
D019833 1312 COMT
catechol-O-methyltransferase (EC:2.1.1.6) Genistein inhibits the reaction [COMT protein results in increased methylation of 4-hydroxyestradiol] decreases reaction
/ increases methylation
protein 18192686
D019833 1312 COMT
catechol-O-methyltransferase (EC:2.1.1.6) Genistein results in decreased activity of COMT protein decreases activity
protein 18192686
18497090
D019833 1312 COMT
catechol-O-methyltransferase (EC:2.1.1.6) Genistein results in decreased expression of COMT mRNA decreases expression
mRNA 18192686
18497090
D019833 118881 COMTD1
catechol-O-methyltransferase domain containing 1 ESR2 promotes the reaction [Genistein results in increased expression of COMTD1 protein] increases expression
/ increases reaction
protein 20884965
D019833 118881 COMTD1
catechol-O-methyltransferase domain containing 1 Genistein results in increased expression of COMTD1 protein increases expression
protein 20884965
D019833 23603 CORO1C
HCRNN4
coronin, actin binding protein, 1C Genistein results in increased expression of CORO1C mRNA increases expression
mRNA 19371625
D019833 23406 COTL1
CLP
coactosin-like 1 (Dictyostelium) ESR2 promotes the reaction [Genistein results in decreased expression of COTL1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 23406 COTL1
CLP
coactosin-like 1 (Dictyostelium) Genistein results in decreased expression of COTL1 protein decreases expression
protein 20884965
D019833 4512 COX1
COI
MTCO1
MT-CO1
cytochrome c oxidase subunit I Genistein results in increased expression of COX1 mRNA increases expression
mRNA 20706672
D019833 9167 COX7A2L
COX7AR
COX7RP
EB1
SIG81
cytochrome c oxidase subunit VIIa polypeptide 2 like ESR2 promotes the reaction [Genistein results in decreased expression of COX7A2L protein] decreases expression
/ increases reaction
protein 20884965
D019833 9167 COX7A2L
COX7AR
COX7RP
EB1
SIG81
cytochrome c oxidase subunit VIIa polypeptide 2 like Genistein results in decreased expression of COX7A2L protein decreases expression
protein 20884965
D019833 9167 COX7A2L
COX7AR
COX7RP
EB1
SIG81
cytochrome c oxidase subunit VIIa polypeptide 2 like Genistein results in increased expression of COX7A2L mRNA increases expression
mRNA 17266178
D019833 1357 CPA1
CPA
carboxypeptidase A1 (pancreatic) (EC:3.4.17.1) Genistein results in decreased expression of CPA1 mRNA decreases expression
mRNA 23019147
D019833 1374 CPT1A
CPT1
CPT1-L
L-CPT1
carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21) [Genistein co-treated with Carnitine] results in increased expression of CPT1A protein affects cotreatment
/ increases expression
protein 16362726
D019833 1374 CPT1A
CPT1
CPT1-L
L-CPT1
carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21) Genistein results in increased expression of CPT1A mRNA increases expression
mRNA 16362726
D019833 1396 CRIP1
CRHP
CRIP
CRP-1
CRP1
cysteine-rich protein 1 (intestinal) ESR2 promotes the reaction [Genistein results in increased expression of CRIP1 protein] increases expression
/ increases reaction
protein 20884965
D019833 1396 CRIP1
CRHP
CRIP
CRP-1
CRP1
cysteine-rich protein 1 (intestinal) Genistein results in increased expression of CRIP1 protein increases expression
protein 20884965
D019833 83690 CRISPLD1
CRISP-10
CRISP10
LCRISP1
cysteine-rich secretory protein LCCL domain containing 1 Genistein results in increased expression of CRISPLD1 mRNA increases expression
mRNA 23019147
D019833 1401 CRP
PTX1
C-reactive protein, pentraxin-related [Genistein co-treated with daidzein] results in decreased expression of CRP protein affects cotreatment
/ decreases expression
protein 16332659
D019833 445748 Genistein results in decreased expression of CSEN mRNA decreases expression
mRNA 18847459
D019833 1465 CSRP1
CRP
CRP1
CSRP
CYRP
D1S181E
cysteine and glycine-rich protein 1 ESR2 promotes the reaction [Genistein results in decreased expression of CSRP1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 1465 CSRP1
CRP
CRP1
CSRP
CYRP
D1S181E
cysteine and glycine-rich protein 1 Genistein results in decreased expression of CSRP1 mRNA decreases expression
mRNA 20884965
D019833 1465 CSRP1
CRP
CRP1
CSRP
CYRP
D1S181E
cysteine and glycine-rich protein 1 Genistein results in decreased expression of CSRP1 protein decreases expression
protein 20884965
D019833 57325 CSRP2BP
ATAC2
CRP2BP
KAT14
PRO1194
dJ717M23.1
CSRP2 binding protein Genistein results in increased expression of CSRP2BP mRNA increases expression
mRNA 16474171
D019833 1475 CSTA
AREI
STF1
STFA
cystatin A (stefin A) Genistein results in increased expression of CSTA mRNA increases expression
mRNA 20884965
D019833 1488 CTBP2
C-terminal binding protein 2 Genistein results in increased expression of CTBP2 mRNA increases expression
mRNA 15256057
D019833 1490 CTGF
CCN2
HCS24
IGFBP8
NOV2
connective tissue growth factor Genistein results in decreased expression of CTGF mRNA decreases expression
mRNA 20884965
D019833 1501 CTNND2
GT24
NPRAP
catenin (cadherin-associated protein), delta 2 Genistein results in increased expression of CTNND2 mRNA increases expression
mRNA 23019147
D019833 1503 CTPS1
CTPS
CTP synthase 1 (EC:6.3.4.2) Genistein results in increased expression of CTPS1 mRNA increases expression
mRNA 16474171
D019833 1075 CTSC
CPPI
DPP-I
DPP1
DPPI
HMS
JP
JPD
PALS
PDON1
PLS
cathepsin C (EC:3.4.14.1) Genistein results in increased expression of CTSC mRNA increases expression
mRNA 20884965
D019833 1509 CTSD
CLN10
CPSD
cathepsin D (EC:3.4.23.5) Genistein results in increased expression of CTSD mRNA increases expression
mRNA 15090535
D019833 8453 CUL2
cullin 2 Genistein results in increased expression of CUL2 mRNA increases expression
mRNA 15256057
D019833 51596 CUTA
ACHAP
C6orf82
cutA divalent cation tolerance homolog (E. coli) Genistein results in decreased expression of CUTA mRNA decreases expression
mRNA 19371625
D019833 1523 CUX1
CASP
CDP
CDP/Cut
CDP1
COY1
CUTL1
CUX
Clox
Cux/CDP
GOLIM6
Nbla10317
p100
p110
p200
p75
cut-like homeobox 1 Genistein results in increased expression of CUX1 mRNA increases expression
mRNA 15256057
D019833 6387 CXCL12
IRH
PBSF
SCYB12
SDF1
TLSF
TPAR1
SDF1A
SDF1B
chemokine (C-X-C motif) ligand 12 bisphenol A inhibits the reaction [Genistein results in increased expression of CXCL12 mRNA] decreases reaction
/ increases expression
mRNA 22549810
D019833 6387 CXCL12
IRH
PBSF
SCYB12
SDF1
TLSF
TPAR1
SDF1A
SDF1B
chemokine (C-X-C motif) ligand 12 bisphenol A inhibits the reaction [Genistein results in increased expression of CXCL12 protein] decreases reaction
/ increases expression
protein 22549810
D019833 6387 CXCL12
IRH
PBSF
SCYB12
SDF1
TLSF
TPAR1
SDF1A
SDF1B
chemokine (C-X-C motif) ligand 12 CXCL12 mRNA affects the susceptibility to Genistein affects response to substance
mRNA 22549810
D019833 6387 CXCL12
IRH
PBSF
SCYB12
SDF1
TLSF
TPAR1
SDF1A
SDF1B
chemokine (C-X-C motif) ligand 12 fulvestrant inhibits the reaction [Genistein results in increased expression of CXCL12 mRNA] decreases reaction
/ increases expression
mRNA 22549810
D019833 6387 CXCL12
IRH
PBSF
SCYB12
SDF1
TLSF
TPAR1
SDF1A
SDF1B
chemokine (C-X-C motif) ligand 12 fulvestrant inhibits the reaction [Genistein results in increased expression of CXCL12 protein] decreases reaction
/ increases expression
protein 22549810
D019833 6387 CXCL12
IRH
PBSF
SCYB12
SDF1
TLSF
TPAR1
SDF1A
SDF1B
chemokine (C-X-C motif) ligand 12 Genistein results in increased expression of CXCL12 mRNA increases expression
mRNA 22549810
D019833 6387 CXCL12
IRH
PBSF
SCYB12
SDF1
TLSF
TPAR1
SDF1A
SDF1B
chemokine (C-X-C motif) ligand 12 Genistein results in increased expression of CXCL12 protein increases expression
protein 22549810
D019833 6387 CXCL12
IRH
PBSF
SCYB12
SDF1
TLSF
TPAR1
SDF1A
SDF1B
chemokine (C-X-C motif) ligand 12 Genistein results in increased secretion of CXCL12 protein increases secretion
protein 20549624
D019833 9547 CXCL14
BMAC
BRAK
KEC
KS1
MIP-2g
MIP2G
NJAC
SCYB14
chemokine (C-X-C motif) ligand 14 Genistein results in decreased expression of CXCL14 mRNA decreases expression
mRNA 15256057
D019833 7852 CXCR4
CD184
D2S201E
FB22
HM89
HSY3RR
LAP3
LCR1
LESTR
NPY3R
NPYR
NPYRL
NPYY3R
WHIM
chemokine (C-X-C motif) receptor 4 CXCR4 protein results in decreased susceptibility to Genistein decreases response to substance
protein 22549810
D019833 1528 CYB5A
CYB5
MCB5
cytochrome b5 type A (microsomal) ESR2 promotes the reaction [Genistein results in decreased expression of CYB5A protein] decreases expression
/ increases reaction
protein 20884965
D019833 1528 CYB5A
CYB5
MCB5
cytochrome b5 type A (microsomal) Genistein results in decreased expression of CYB5A protein decreases expression
protein 20884965
D019833 1535 CYBA
p22-PHOX
cytochrome b-245, alpha polypeptide Genistein results in decreased expression of CYBA mRNA decreases expression
mRNA 16705744
D019833 54205 CYCS
CYC
HCS
THC4
cytochrome c, somatic fulvestrant inhibits the reaction [Genistein affects the localization of CYCS protein] affects localization
/ decreases reaction
protein 16924424
D019833 54205 CYCS
CYC
HCS
THC4
cytochrome c, somatic Genistein affects the localization of CYCS protein affects localization
protein 16924424
D019833 114757 CYGB
HGB
STAP
cytoglobin Genistein results in decreased expression of CYGB mRNA decreases expression
mRNA 20706672
D019833 1540 CYLD
BRSS
CDMT
CYLD1
CYLDI
EAC
MFT
MFT1
SBS
TEM
USPL2
cylindromatosis (turban tumor syndrome) (EC:3.4.19.12) Genistein inhibits the reaction [HIST3H3 protein modified form binds to CYLD promoter] affects binding
/ decreases reaction
promoter 18431742
D019833 1540 CYLD
BRSS
CDMT
CYLD1
CYLDI
EAC
MFT
MFT1
SBS
TEM
USPL2
cylindromatosis (turban tumor syndrome) (EC:3.4.19.12) Genistein results in increased expression of CYLD mRNA increases expression
mRNA 18431742
D019833 1540 CYLD
BRSS
CDMT
CYLD1
CYLDI
EAC
MFT
MFT1
SBS
TEM
USPL2
cylindromatosis (turban tumor syndrome) (EC:3.4.19.12) Genistein results in increased expression of CYLD protein increases expression
protein 18431742
D019833 1588 CYP19A1
ARO
ARO1
CPV1
CYAR
CYP19
CYPXIX
P-450AROM
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) [Genistein co-treated with biochanin A co-treated with daidzein] results in decreased activity of CYP19A1 protein affects cotreatment
/ decreases activity
protein 16965912
D019833 1588 CYP19A1
ARO
ARO1
CPV1
CYAR
CYP19
CYPXIX
P-450AROM
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) [Genistein co-treated with biochanin A co-treated with daidzein] results in decreased expression of CYP19A1 mRNA affects cotreatment
/ decreases expression
mRNA 16965912
D019833 1588 CYP19A1
ARO
ARO1
CPV1
CYAR
CYP19
CYPXIX
P-450AROM
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) Genistein inhibits the reaction [Fadrozole results in increased activity of CYP19A1 protein] decreases reaction
/ increases activity
protein 21854827
D019833 1588 CYP19A1
ARO
ARO1
CPV1
CYAR
CYP19
CYPXIX
P-450AROM
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) Genistein results in decreased activity of CYP19A1 protein decreases activity
protein 15876411
16023337
16965912
D019833 1588 CYP19A1
ARO
ARO1
CPV1
CYAR
CYP19
CYPXIX
P-450AROM
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) Genistein results in decreased expression of CYP19A1 mRNA decreases expression
mRNA 16965912
D019833 1588 CYP19A1
ARO
ARO1
CPV1
CYAR
CYP19
CYPXIX
P-450AROM
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) Genistein results in increased activity of CYP19A1 protein increases activity
protein 15319488
D019833 1588 CYP19A1
ARO
ARO1
CPV1
CYAR
CYP19
CYPXIX
P-450AROM
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) Genistein results in increased expression of CYP19A1 mRNA increases expression
mRNA 15319488
19549922
D019833 1588 CYP19A1
ARO
ARO1
CPV1
CYAR
CYP19
CYPXIX
P-450AROM
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) Genistein results in increased expression of CYP19A1 protein increases expression
protein 21854827
D019833 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) [Genistein co-treated with triclocarban] results in increased expression of CYP1A1 mRNA affects cotreatment
/ increases expression
mRNA 23524099
D019833 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Genistein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] decreases reaction
/ increases expression
mRNA 10696073
18451504
20057149
D019833 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Genistein results in decreased activity of CYP1A1 protein decreases activity
protein 18497090
21053930
D019833 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Genistein results in decreased expression of CYP1A1 mRNA decreases expression
mRNA 16474171
18451504
18497090
20884965
23019147
D019833 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Genistein results in increased activity of CYP1A1 protein increases activity
protein 19766177
D019833 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Genistein results in increased expression of CYP1A1 mRNA increases expression
mRNA 16474171
D019833 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) CYP1A2 protein results in increased chemical synthesis of Genistein increases chemical synthesis
protein 12814970
D019833 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) CYP1A2 protein results in increased metabolism of Genistein increases metabolic processing
protein 12814970
D019833 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) Genistein results in decreased activity of CYP1A2 protein decreases activity
protein 20806393
21053930
D019833 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) CYP1B1 protein affects the chemical synthesis of Genistein affects chemical synthesis
protein 15479032
D019833 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) Genistein binds to and results in decreased activity of CYP1B1 protein affects binding
/ decreases activity
protein 21053930
D019833 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) Genistein results in decreased activity of CYP1B1 protein decreases activity
protein 15479032
D019833 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) Genistein results in decreased expression of CYP1B1 mRNA decreases expression
mRNA 15257099
16474171
D019833 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) Genistein results in increased expression of CYP1B1 mRNA increases expression
mRNA 16474171
23524099
D019833 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) triclocarban promotes the reaction [Genistein results in increased expression of CYP1B1 mRNA] increases expression
/ increases reaction
mRNA 23524099
D019833 1591 CYP24A1
CP24
CYP24
HCAI
P450-CC24
cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) Genistein inhibits the reaction [Calcitriol results in increased activity of CYP24A1 protein] decreases reaction
/ increases activity
protein 15955619
D019833 1591 CYP24A1
CP24
CYP24
HCAI
P450-CC24
cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) Genistein inhibits the reaction [CYP24A1 protein results in increased degradation of Calcitriol] decreases reaction
/ increases degradation
protein 15955619
D019833 1591 CYP24A1
CP24
CYP24
HCAI
P450-CC24
cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) Genistein promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] increases expression
/ increases reaction
mRNA 15955619
D019833 1591 CYP24A1
CP24
CYP24
HCAI
P450-CC24
cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) Genistein results in decreased activity of CYP24A1 protein decreases activity
protein 15955619
D019833 1594 CYP27B1
CP2B
CYP1
CYP1alpha
CYP27B
P450c1
PDDR
VDD1
VDDR
VDDRI
VDR
cytochrome P450, family 27, subfamily B, polypeptide 1 (EC:1.14.13.13) Genistein affects the activity of CYP27B1 protein affects activity
protein 17659868
D019833 1594 CYP27B1
CP2B
CYP1
CYP1alpha
CYP27B
P450c1
PDDR
VDD1
VDDR
VDDRI
VDR
cytochrome P450, family 27, subfamily B, polypeptide 1 (EC:1.14.13.13) Genistein affects the expression of CYP27B1 mRNA affects expression
mRNA 17659868
D019833 1594 CYP27B1
CP2B
CYP1
CYP1alpha
CYP27B
P450c1
PDDR
VDD1
VDDR
VDDRI
VDR
cytochrome P450, family 27, subfamily B, polypeptide 1 (EC:1.14.13.13) Genistein results in increased activity of CYP27B1 protein increases activity
protein 15795327
D019833 1594 CYP27B1
CP2B
CYP1
CYP1alpha
CYP27B
P450c1
PDDR
VDD1
VDDR
VDDRI
VDR
cytochrome P450, family 27, subfamily B, polypeptide 1 (EC:1.14.13.13) Genistein results in increased expression of CYP27B1 mRNA increases expression
mRNA 15795327
D019833 1559 CYP2C9
CPC9
CYP2C
CYP2C10
CYPIIC9
P450IIC9
cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) Genistein inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] decreases reaction
/ increases hydroxylation
protein 21053930
D019833 1576 CYP3A4
CP33
CP34
CYP3A
CYP3A3
CYPIIIA3
CYPIIIA4
HLP
NF-25
P450C3
P450PCN1
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) Genistein inhibits the reaction [Calcitriol results in increased activity of CYP3A4 protein] decreases reaction
/ increases activity
protein 19766177
D019833 1576 CYP3A4
CP33
CP34
CYP3A
CYP3A3
CYPIIIA3
CYPIIIA4
HLP
NF-25
P450C3
P450PCN1
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) Genistein results in decreased activity of CYP3A4 protein decreases activity
protein 21053930
D019833 10858 CYP46A1
CP46
CYP46
cytochrome P450, family 46, subfamily A, polypeptide 1 (EC:1.14.13.98) Genistein results in increased expression of CYP46A1 mRNA increases expression
mRNA 18847459
D019833 1580 CYP4B1
CYPIVB1
P-450HP
cytochrome P450, family 4, subfamily B, polypeptide 1 (EC:1.14.14.1) Genistein results in decreased expression of CYP4B1 mRNA decreases expression
mRNA 18444173
D019833 8529 CYP4F2
CPF2
cytochrome P450, family 4, subfamily F, polypeptide 2 (EC:1.14.13.30) (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Genistein results in increased expression of CYP4F2 mRNA] decreases reaction
/ increases expression
mRNA 21205922
D019833 8529 CYP4F2
CPF2
cytochrome P450, family 4, subfamily F, polypeptide 2 (EC:1.14.13.30) Genistein results in increased expression of CYP4F2 mRNA increases expression
mRNA 21205922
D019833 8529 CYP4F2
CPF2
cytochrome P450, family 4, subfamily F, polypeptide 2 (EC:1.14.13.30) STO 609 inhibits the reaction [Genistein results in increased expression of CYP4F2 mRNA] decreases reaction
/ increases expression
mRNA 21205922
D019833 3491 CYR61
CCN1
GIG1
IGFBP10
cysteine-rich, angiogenic inducer, 61 Genistein results in decreased expression of CYR61 mRNA decreases expression
mRNA 20884965
D019833 9267 CYTH1
B2-1
CYTOHESIN-1
D17S811E
PSCD1
SEC7
cytohesin 1 Genistein results in decreased expression of CYTH1 mRNA decreases expression
mRNA 16705744
D019833 9265 CYTH3
ARNO3
GRP1
PSCD3
cytohesin 3 Genistein results in decreased expression of CYTH3 mRNA decreases expression
mRNA 16705744
D019833 1603 DAD1
OST2
defender against cell death 1 (EC:2.4.99.18) Genistein results in increased expression of DAD1 mRNA increases expression
mRNA 16474171
D019833 55861 DBNDD2
C20orf35
CK1BP
HSMNP1
dysbindin (dystrobrevin binding protein 1) domain containing 2 Genistein results in decreased expression of DBNDD2 mRNA decreases expression
mRNA 18847459
D019833 1638 DCT
TRP-2
TYRP2
dopachrome tautomerase (EC:5.3.3.12) Genistein results in decreased expression of DCT mRNA decreases expression
mRNA 16705744
18444173
D019833 51181 DCXR
DCR
HCR2
HCRII
KIDCR
P34H
SDR20C1
XR
dicarbonyl/L-xylulose reductase (EC:1.1.1.10) Genistein results in increased expression of DCXR mRNA increases expression
mRNA 18847459
D019833 1644 DDC
AADC
dopa decarboxylase (aromatic L-amino acid decarboxylase) (EC:4.1.1.28) Genistein results in increased expression of DDC mRNA increases expression
mRNA 15378649
D019833 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 Genistein results in decreased expression of DDIT3 mRNA decreases expression
mRNA 20884965
D019833 1649 DDIT3
CEBPZ
CHOP
CHOP-10
CHOP10
GADD153
DNA-damage-inducible transcript 3 Genistein results in increased expression of DDIT3 mRNA increases expression
mRNA 18847459
D019833 65992 DDRGK1
C20orf116
UFBP1
dJ1187M17.3
DDRGK domain containing 1 ESR2 promotes the reaction [Genistein results in decreased expression of DDRGK1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 65992 DDRGK1
C20orf116
UFBP1
dJ1187M17.3
DDRGK domain containing 1 Genistein results in decreased expression of DDRGK1 protein decreases expression
protein 20884965
D019833 123099 DEGS2
C14orf66
DES2
FADS8
delta(4)-desaturase, sphingolipid 2 Genistein results in increased expression of DEGS2 mRNA increases expression
mRNA 23019147
D019833 55789 DEPDC1B
BRCC3
XTP1
DEP domain containing 1B Genistein results in increased expression of DEPDC1B mRNA increases expression
mRNA 16474171
D019833 420357 Genistein results in increased expression of DEPDC6 mRNA increases expression
mRNA 23019147
D019833 1677 DFFB
CAD
CPAN
DFF-40
DFF2
DFF40
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) Genistein results in increased expression of DFFB mRNA increases expression
mRNA 15256057
D019833 84649 DGAT2
ARAT
GS1999FULL
diacylglycerol O-acyltransferase 2 (EC:2.3.1.20 2.3.1.76) Genistein results in increased expression of DGAT2 mRNA increases expression
mRNA 20884965
D019833 8526 DGKE
DAGK5
DAGK6
DGK
NPHS7
diacylglycerol kinase, epsilon 64kDa (EC:2.7.1.107) Genistein results in increased expression of DGKE mRNA increases expression
mRNA 23019147
D019833 1718 DHCR24
DCE
Nbla03646
SELADIN1
seladin-1
24-dehydrocholesterol reductase (EC:1.3.1.72) Genistein results in decreased expression of DHCR24 mRNA decreases expression
mRNA 15378649
D019833 200895 DHFRL1
DHFRP4
dihydrofolate reductase-like 1 (EC:1.5.1.3) Genistein results in increased expression of DHFRL1 mRNA increases expression
mRNA 18847459
D019833 308585 Genistein results in decreased expression of DHRS10 mRNA decreases expression
mRNA 19371625
D019833 10202 DHRS2
HEP27
SDR25C1
dehydrogenase/reductase (SDR family) member 2 Genistein results in increased expression of DHRS2 mRNA increases expression
mRNA 16474171
D019833 9249 DHRS3
DD83.1
RDH17
Rsdr1
SDR1
SDR16C1
retSDR1
dehydrogenase/reductase (SDR family) member 3 (EC:1.1.1.300) Genistein results in increased expression of DHRS3 mRNA increases expression
mRNA 19371625
23019147
D019833 22943 DKK1
DKK-1
SK
dickkopf WNT signaling pathway inhibitor 1 Genistein results in decreased expression of DKK1 mRNA decreases expression
mRNA 20884965
D019833 9231 DLG5
LP-DLG
P-DLG5
PDLG
discs, large homolog 5 (Drosophila) Genistein results in increased expression of DLG5 mRNA increases expression
mRNA 23019147
D019833 9787 DLGAP5
DLG7
HURP
discs, large (Drosophila) homolog-associated protein 5 Genistein affects the expression of DLGAP5 mRNA affects expression
mRNA 18847459
D019833 1756 DMD
BMD
CMD3B
DXS142
DXS164
DXS206
DXS230
DXS239
DXS268
DXS269
DXS270
DXS272
dystrophin ESR2 promotes the reaction [Genistein results in decreased expression of DMD protein] decreases expression
/ increases reaction
protein 20884965
D019833 1756 DMD
BMD
CMD3B
DXS142
DXS164
DXS206
DXS230
DXS239
DXS268
DXS269
DXS270
DXS272
dystrophin Genistein results in decreased expression of DMD protein decreases expression
protein 20884965
D019833 4189 DNAJB9
ERdj4
MDG-1
MDG1
MST049
MSTP049
DnaJ (Hsp40) homolog, subfamily B, member 9 Genistein results in increased expression of DNAJB9 mRNA increases expression
mRNA 15378649
D019833 55192 DNAJC17
DnaJ (Hsp40) homolog, subfamily C, member 17 Genistein results in decreased expression of DNAJC17 mRNA decreases expression
mRNA 18847459
D019833 134218 DNAJC21
DNAJA5
GS3
JJJ1
DnaJ (Hsp40) homolog, subfamily C, member 21 Genistein results in increased expression of DNAJC21 mRNA increases expression
mRNA 18847459
D019833 1786 DNMT1
ADCADN
AIM
CXXC9
DNMT
HSN1E
MCMT
DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) Genistein results in decreased expression of DNMT1 mRNA decreases expression
mRNA 16705744
D019833 1786 DNMT1
ADCADN
AIM
CXXC9
DNMT
HSN1E
MCMT
DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) Genistein results in decreased expression of DNMT1 protein decreases expression
protein 19221000
D019833 1789 DNMT3B
ICF
ICF1
M.HsaIIIB
DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37) Genistein results in decreased expression of DNMT3B protein decreases expression
protein 19221000
D019833 23549 DNPEP
ASPEP
DAP
aspartyl aminopeptidase (EC:3.4.11.21) ESR2 promotes the reaction [Genistein results in decreased expression of DNPEP protein] decreases expression
/ increases reaction
protein 20884965
D019833 23549 DNPEP
ASPEP
DAP
aspartyl aminopeptidase (EC:3.4.11.21) Genistein results in decreased expression of DNPEP protein decreases expression
protein 20884965
D019833 1795 DOCK3
MOCA
PBP
dedicator of cytokinesis 3 [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of DOCK3 mRNA affects cotreatment
/ decreases expression
mRNA 16963248
D019833 83475 DOHH
HLRC1
hDOHH
deoxyhypusine hydroxylase/monooxygenase (EC:1.14.99.29) Genistein results in increased expression of DOHH mRNA increases expression
mRNA 23019147
D019833 55715 DOK4
docking protein 4 Genistein results in increased expression of DOK4 mRNA increases expression
mRNA 19371625
D019833 285489 DOK7
C4orf25
CMS1B
docking protein 7 Genistein results in increased expression of DOK7 mRNA increases expression
mRNA 23019147
D019833 1819 DRG2
developmentally regulated GTP binding protein 2 Genistein results in decreased expression of DRG2 mRNA decreases expression
mRNA 16705744
D019833 1819 DRG2
developmentally regulated GTP binding protein 2 Genistein results in increased expression of DRG2 mRNA increases expression
mRNA 16705744
D019833 1830 DSG3
CDHF6
PVA
desmoglein 3 Genistein results in decreased expression of DSG3 mRNA decreases expression
mRNA 20706672
D019833 51514 DTL
CDT2
DCAF2
L2DTL
RAMP
denticleless E3 ubiquitin protein ligase homolog (Drosophila) Genistein results in increased expression of DTL mRNA increases expression
mRNA 16474171
D019833 23220 DTX4
RNF155
deltex homolog 4 (Drosophila) Genistein results in increased expression of DTX4 mRNA increases expression
mRNA 20884965
D019833 1841 DTYMK
CDC8
PP3731
TMPK
TYMK
deoxythymidylate kinase (thymidylate kinase) (EC:2.7.4.9) Genistein results in increased expression of DTYMK mRNA increases expression
mRNA 16474171
D019833 1843 DUSP1
CL100
HVH1
MKP-1
MKP1
PTPN10
dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) Genistein results in decreased expression of DUSP1 mRNA decreases expression
mRNA 20884965
D019833 1843 DUSP1
CL100
HVH1
MKP-1
MKP1
PTPN10
dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) Genistein results in increased expression of DUSP1 mRNA increases expression
mRNA 16705744
D019833 1844 DUSP2
PAC-1
PAC1
dual specificity phosphatase 2 (EC:3.1.3.16 3.1.3.48) Genistein results in increased expression of DUSP2 mRNA increases expression
mRNA 23019147
D019833 1846 DUSP4
HVH2
MKP-2
MKP2
TYP
dual specificity phosphatase 4 (EC:3.1.3.16 3.1.3.48) Genistein results in decreased expression of DUSP4 mRNA decreases expression
mRNA 16865672
D019833 1847 DUSP5
DUSP
HVH3
dual specificity phosphatase 5 (EC:3.1.3.16 3.1.3.48) Genistein results in decreased expression of DUSP5 mRNA decreases expression
mRNA 20884965
D019833 1848 DUSP6
HH19
MKP3
PYST1
dual specificity phosphatase 6 (EC:3.1.3.16 3.1.3.48) Genistein results in increased expression of DUSP6 mRNA increases expression
mRNA 23019147
D019833 1855 DVL1
DVL
DVL1L1
DVL1P1
dishevelled segment polarity protein 1 Genistein results in increased expression of DVL1 mRNA increases expression
mRNA 23019147
D019833 1870 E2F2
E2F-2
E2F transcription factor 2 Genistein results in decreased expression of E2F2 mRNA decreases expression
mRNA 18847459
D019833 9166 EBAG9
EB9
PDAF
estrogen receptor binding site associated, antigen, 9 Genistein results in increased expression of EBAG9 mRNA increases expression
mRNA 17266178
D019833 10682 EBP
CDPX2
CHO2
CPX
CPXD
emopamil binding protein (sterol isomerase) (EC:5.3.3.5) Genistein results in increased expression of EBP mRNA increases expression
mRNA 16474171
D019833 1889 ECE1
ECE
endothelin converting enzyme 1 (EC:3.4.24.71) Genistein results in decreased expression of ECE1 mRNA decreases expression
mRNA 16399490
D019833 1891 ECH1
HPXEL
enoyl CoA hydratase 1, peroxisomal Genistein results in decreased expression of ECH1 mRNA decreases expression
mRNA 19371625
D019833 1894 ECT2
ARHGEF31
epithelial cell transforming sequence 2 oncogene Genistein results in increased expression of ECT2 mRNA increases expression
mRNA 16474171
D019833 23644 EDC4
GE1
Ge-1
HEDL5
HEDLS
RCD-8
RCD8
enhancer of mRNA decapping 4 Genistein results in decreased expression of EDC4 mRNA decreases expression
mRNA 16705744
D019833 1906 EDN1
ET1
HDLCQ7
PPET1
endothelin 1 Genistein affects the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]] affects binding
/ affects reaction
/ increases reaction
promoter 10939628
D019833 1906 EDN1
ET1
HDLCQ7
PPET1
endothelin 1 Genistein affects the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]] affects binding
/ affects reaction
/ increases reaction
promoter 10939628
D019833 1906 EDN1
ET1
HDLCQ7
PPET1
endothelin 1 Genistein inhibits the reaction [cobaltous chloride results in increased expression of EDN1 mRNA] decreases reaction
/ increases expression
mRNA 10939628
D019833 1906 EDN1
ET1
HDLCQ7
PPET1
endothelin 1 Genistein inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 mRNA] decreases reaction
/ increases expression
mRNA 10939628
D019833 1907 EDN2
ET2
PPET2
endothelin 2 Genistein results in decreased expression of EDN2 mRNA decreases expression
mRNA 16399490
D019833 1938 EEF2
EEF-2
EF-2
EF2
SCA26
eukaryotic translation elongation factor 2 Genistein results in decreased expression of EEF2 mRNA decreases expression
mRNA 16705744
D019833 80303 EFHD1
MST133
MSTP133
SWS2
EF-hand domain family, member D1 ESR2 promotes the reaction [Genistein results in increased expression of EFHD1 protein] increases expression
/ increases reaction
protein 20884965
D019833 80303 EFHD1
MST133
MSTP133
SWS2
EF-hand domain family, member D1 Genistein results in increased expression of EFHD1 protein increases expression
protein 20884965
D019833 1948 EFNB2
EPLG5
HTKL
Htk-L
LERK5
ephrin-B2 Genistein results in decreased expression of EFNB2 mRNA decreases expression
mRNA 16474171
D019833 1950 EGF
HOMG4
URG
epidermal growth factor Genistein inhibits the reaction [EGF protein results in increased activity of AKT1 protein] decreases reaction
/ increases activity
protein 18431742
D019833 1950 EGF
HOMG4
URG
epidermal growth factor Genistein results in decreased expression of EGF mRNA decreases expression
mRNA 20706672
D019833 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) [Genistein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA affects cotreatment
/ decreases expression
mRNA 19347870
D019833 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) [Genistein co-treated with ESR1 protein] results in decreased expression of EGFR protein affects cotreatment
/ decreases expression
protein 19347870
D019833 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) [Genistein co-treated with ESR2 protein] results in decreased expression of EGFR mRNA affects cotreatment
/ decreases expression
mRNA 19347870
D019833 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) [Genistein co-treated with ESR2 protein] results in decreased expression of EGFR protein affects cotreatment
/ decreases expression
protein 19347870
D019833 1956 EGFR
ERBB
ERBB1
HER1
PIG61
mENA
epidermal growth factor receptor (EC:2.7.10.1) Genistein results in decreased expression of EGFR mRNA decreases expression
mRNA 15257099
D019833 1958 EGR1
AT225
G0S30
KROX-24
NGFI-A
TIS8
ZIF-268
ZNF225
early growth response 1 Genistein results in increased expression of EGR1 mRNA increases expression
mRNA 15257099
23019147
D019833 1960 EGR3
EGR-3
PILOT
early growth response 3 Genistein results in increased expression of EGR3 mRNA increases expression
mRNA 15159206
D019833 1981 EIF4G1
EIF-4G1
EIF4F
EIF4G
EIF4GI
P220
PARK18
eukaryotic translation initiation factor 4 gamma, 1 ESR2 promotes the reaction [Genistein results in decreased expression of EIF4G1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 1981 EIF4G1
EIF-4G1
EIF4F
EIF4G
EIF4GI
P220
PARK18
eukaryotic translation initiation factor 4 gamma, 1 Genistein results in decreased expression of EIF4G1 protein decreases expression
protein 20884965
D019833 1984 EIF5A
EIF-5A
EIF5A1
eIF5AI
eukaryotic translation initiation factor 5A Genistein results in decreased expression of EIF5A mRNA decreases expression
mRNA 16705744
D019833 64834 ELOVL1
Ssc1
ELOVL fatty acid elongase 1 (EC:2.3.1.199) ESR2 promotes the reaction [Genistein results in increased expression of ELOVL1 protein] increases expression
/ increases reaction
protein 20884965
D019833 64834 ELOVL1
Ssc1
ELOVL fatty acid elongase 1 (EC:2.3.1.199) Genistein results in increased expression of ELOVL1 protein increases expression
protein 20884965
D019833 83401 ELOVL3
CIG-30
CIG30
ELOVL fatty acid elongase 3 (EC:2.3.1.199) Genistein results in increased expression of ELOVL3 mRNA increases expression
mRNA 20884965
D019833 60481 ELOVL5
HELO1
dJ483K16.1
ELOVL fatty acid elongase 5 (EC:2.3.1.199) Genistein results in decreased expression of ELOVL5 mRNA decreases expression
mRNA 15378649
D019833 2013 EMP2
XMP
epithelial membrane protein 2 Genistein results in increased expression of EMP2 mRNA increases expression
mRNA 16474171
D019833 2026 ENO2
NSE
enolase 2 (gamma, neuronal) (EC:4.2.1.11) Genistein results in decreased expression of ENO2 mRNA decreases expression
mRNA 15159206
D019833 2027 ENO3
GSD13
MSE
enolase 3 (beta, muscle) (EC:4.2.1.11) Genistein results in decreased expression of ENO3 mRNA decreases expression
mRNA 15757668
D019833 5168 ENPP2
ATX
ATX-X
AUTOTAXIN
LysoPLD
NPP2
PD-IALPHA
PDNP2
ectonucleotide pyrophosphatase/phosphodiesterase 2 (EC:3.1.4.39) Genistein results in decreased expression of ENPP2 mRNA decreases expression
mRNA 15256057
D019833 2036 EPB41L1
4.1N
MRD11
erythrocyte membrane protein band 4.1-like 1 Genistein results in increased expression of EPB41L1 mRNA increases expression
mRNA 23019147
D019833 2037 EPB41L2
4.1-G
4.1G
erythrocyte membrane protein band 4.1-like 2 Genistein results in increased expression of EPB41L2 mRNA increases expression
mRNA 19371625
23019147
D019833 2041 EPHA1
EPH
EPHT
EPHT1
EPH receptor A1 (EC:2.7.10.1) [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of EPHA1 mRNA affects cotreatment
/ increases expression
mRNA 16963248
D019833 2050 EPHB4
HTK
MYK1
TYRO11
EPH receptor B4 (EC:2.7.10.1) Genistein results in decreased expression of EPHB4 mRNA decreases expression
mRNA 16705744
D019833 2052 EPHX1
EPHX
EPOX
HYL1
MEH
epoxide hydrolase 1, microsomal (xenobiotic) (EC:3.3.2.9) Genistein results in increased expression of EPHX1 mRNA increases expression
mRNA 18847459
D019833 2053 EPHX2
CEH
SEH
epoxide hydrolase 2, cytoplasmic (EC:3.3.2.10 3.1.3.76) ESR2 promotes the reaction [Genistein results in increased expression of EPHX2 protein] increases expression
/ increases reaction
protein 20884965
D019833 2053 EPHX2
CEH
SEH
epoxide hydrolase 2, cytoplasmic (EC:3.3.2.10 3.1.3.76) Genistein results in increased expression of EPHX2 protein increases expression
protein 20884965
D019833 2057 EPOR
EPO-R
erythropoietin receptor Genistein results in increased expression of EPOR mRNA increases expression
mRNA 16705744
D019833 2068 ERCC2
COFS2
EM9
TTD
XPD
excision repair cross-complementing rodent repair deficiency, complementation group 2 (EC:3.6.4.12) Genistein results in decreased expression of ERCC2 mRNA decreases expression
mRNA 16705744
D019833 2071 ERCC3
BTF2
GTF2H
RAD25
TFIIH
XPB
excision repair cross-complementing rodent repair deficiency, complementation group 3 (EC:3.6.4.12) Genistein results in increased expression of ERCC3 mRNA increases expression
mRNA 19371625
D019833 1161 ERCC8
CKN1
CSA
UVSS2
excision repair cross-complementing rodent repair deficiency, complementation group 8 Genistein results in increased expression of ERCC8 mRNA increases expression
mRNA 16705744
D019833 11160 ERLIN2
C8orf2
Erlin-2
NET32
SPFH2
SPG18
ER lipid raft associated 2 Genistein results in decreased expression of ERLIN2 mRNA decreases expression
mRNA 16705744
D019833 83715 ESPN
DFNB36
espin [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ESPN mRNA affects cotreatment
/ decreases expression
mRNA 16963248
D019833 83715 ESPN
DFNB36
espin Genistein results in increased expression of ESPN mRNA increases expression
mRNA 19371625
23019147
D019833 284729 ESPNP
RP1-163M9.1
dJ1182A14.1
espin pseudogene Genistein results in increased expression of ESPNP mRNA increases expression
mRNA 23019147
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [Genistein binds to and results in increased activity of ESR1 protein] affects binding
/ decreases reaction
/ increases activity
protein 11861976
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane promotes the reaction [Genistein binds to and results in increased activity of ESR1 protein] affects binding
/ increases activity
/ increases reaction
protein 11861976
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [afimoxifene binds to and results in decreased activity of ESR1 protein] which results in decreased susceptibility to Genistein affects binding
/ decreases activity
/ decreases response to substance
protein 19427779
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 beta Carotene inhibits the reaction [Genistein results in increased activity of ESR1 protein] decreases reaction
/ increases activity
protein 17051425
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of ACTBL2 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of APLP2 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of BCKDHA protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of CHCHD1 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of CHMP2B protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of HMGN1 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of HNRNPC protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of KPRP protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of LGALS7 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of LMNA protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of LMNB1 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of LPP protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of MAP4 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of MOGS protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of MYO15A protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of NASP protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of NFS1 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of NLN protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of NPC2 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of PIP protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of PNKD protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of POFUT1 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of RPS16 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of RPS18 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of RPS25 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of RPS29 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of S100A8 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of S100A9 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of SEPHS1 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of SYAP1 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of THOC2 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of TIMM10B protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of TOMM40 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of TPR protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in decreased expression of VAT1 protein] decreases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of ASNS protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of CCDC25 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of FAM129A protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of KRT18 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of KRT19 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of KRT8 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of MGP protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of MRPL20 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of MYH10 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of MYH14 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of MYH9 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of MYL12B protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of MYL6 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of NBN protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of NFAT5 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of NPM1 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of RCN1 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of RPL23AP37 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of SLC3A2 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of SLC7A5 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of TMEM120A protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 promotes the reaction [Genistein results in increased expression of TTBK2 protein] increases expression
/ increases reaction
20884965
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 protein affects the susceptibility to Genistein affects response to substance
protein 17275032
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 protein inhibits the reaction [Genistein results in increased expression of PGR mRNA] decreases reaction
/ increases expression
protein 23384675
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 protein inhibits the reaction [Genistein results in increased expression of PRSS23 mRNA] decreases reaction
/ increases expression
protein 23384675
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 protein inhibits the reaction [Genistein results in increased expression of TFF1 mRNA] decreases reaction
/ increases expression
protein 23384675
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 ESR1 protein inhibits the reaction [Genistein results in increased expression of WISP2 mRNA] decreases reaction
/ increases expression
protein 23384675
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [Estradiol co-treated with Genistein co-treated with o,p'-DDT] affects the expression of ESR1 mRNA affects cotreatment
/ affects expression
mRNA 11922773
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [fulvestrant binds to and results in decreased activity of ESR1 protein] which results in decreased susceptibility to Genistein affects binding
/ decreases activity
/ decreases response to substance
protein 19427779
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 fulvestrant inhibits the reaction [[Genistein binds to ESR1 protein] which results in increased activity of ALPL protein] affects binding
/ decreases reaction
/ increases activity
protein 12650720
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 fulvestrant inhibits the reaction [Genistein results in increased activity of ESR1 protein] decreases reaction
/ increases activity
protein 20599613
22562034
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein binds to and results in increased activity of ESR1 protein affects binding
/ increases activity
protein 9751507
10397250
11502892
11861976
12765243
15026083
15876408
15937998
16076101
16541309
20362049
20435135
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein binds to ESR1 protein affects binding
protein 11162928
11368622
11518614
11999068
12598185
14579009
15521089
16506809
16566672
17400923
18692112
19913605
20074635
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [Genistein binds to ESR1 protein] which binds to NCOA2 protein affects binding
protein 15123288
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [Genistein binds to ESR1 protein] which results in increased activity of ALPL protein affects binding
/ increases activity
protein 12650720
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [Genistein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA affects cotreatment
/ decreases expression
protein 19347870
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [Genistein co-treated with ESR1 protein] results in decreased expression of EGFR protein affects cotreatment
/ decreases expression
protein 19347870
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [Genistein co-treated with ESR1 protein] results in increased expression of BGLAP mRNA affects cotreatment
/ increases expression
protein 19347870
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [Genistein co-treated with ESR1 protein] results in increased expression of LTF mRNA affects cotreatment
/ increases expression
protein 21783566
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 [Genistein co-treated with ESR1] results in increased expression of BSP mRNA affects cotreatment
/ increases expression
19347870
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein inhibits the reaction [16 alpha-iodoestradiol binds to ESR1 protein] affects binding
/ decreases reaction
protein 9048584
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein inhibits the reaction [Estradiol binds to ESR1 protein] affects binding
/ decreases reaction
protein 10964929
11368622
14579009
16566672
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein inhibits the reaction [Estradiol results in increased activity of ESR1 protein] decreases reaction
/ increases activity
protein 16434996
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein promotes the reaction [ESR1 protein binds to ESR1 protein] affects binding
/ increases reaction
protein 15713566
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein promotes the reaction [ESR1 protein binds to GREB1 promoter] affects binding
/ increases reaction
protein 23019147
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein promotes the reaction [ESR1 protein binds to JUND promoter] affects binding
/ increases reaction
protein 23019147
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein promotes the reaction [ESR1 protein binds to NCOA1 protein] affects binding
/ increases reaction
protein 10964929
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein promotes the reaction [ESR1 protein binds to NCOA2 protein] affects binding
/ increases reaction
protein 10964929
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein promotes the reaction [Estradiol results in increased activity of ESR1 protein] increases activity
/ increases reaction
protein 16118406
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein promotes the reaction [NCOA2 protein binds to ESR1 protein] affects binding
/ increases reaction
protein 15084758
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein results in decreased expression of ESR1 mRNA decreases expression
mRNA 11502892
15968319
16033089
23524099
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein results in decreased expression of ESR1 protein decreases expression
protein 11502892
16033089
16541309
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein results in increased activity of ESR1 protein increases activity
protein 11485867
14975756
16118406
17132221
19161236
20599613
22562034
23019147
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Genistein results in increased expression of ESR1 mRNA increases expression
mRNA 11922773
15968319
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Methoxychlor metabolite inhibits the reaction [Genistein binds to and results in increased activity of ESR1 protein] affects binding
/ decreases reaction
/ increases activity
protein 11861976
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 Methoxychlor metabolite promotes the reaction [Genistein binds to and results in increased activity of ESR1 protein] affects binding
/ increases activity
/ increases reaction
protein 11861976
D019833 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 RU 58668 promotes the reaction [fulvestrant inhibits the reaction [Genistein results in increased activity of ESR1 protein]] decreases reaction
/ increases activity
/ increases reaction
protein 20599613
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [Genistein binds to and results in increased activity of ESR2 protein] affects binding
/ decreases reaction
/ increases activity
protein 11861976
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) beta Carotene inhibits the reaction [Genistein results in increased activity of ESR2 protein] decreases reaction
/ increases activity
protein 17051425
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 affects the reaction [Genistein results in increased expression of CDKN1A] affects reaction
/ increases expression
21161820
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 affects the susceptibility to Genistein affects response to substance
21161820
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 gene polymorphism affects the reaction [[Genistein co-treated with daidzein] affects the expression of VCAM1 protein] affects cotreatment
/ affects expression
/ affects reaction
gene 16332659
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 gene polymorphism affects the susceptibility to [Genistein co-treated with daidzein] affects cotreatment
/ affects response to substance
gene 16332659
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of ABAT protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of ACLY protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of ACOX1 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of ADSL protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of ANXA1 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of ANXA3 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of ARMCX3 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of BAG5 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of CNN2 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of COTL1 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of COX7A2L protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of CSRP1 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of CYB5A protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of DDRGK1 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of DMD protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of DNPEP protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of EIF4G1 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of ESR2 protein] decreases expression
/ increases reaction
protein 20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of FHL2 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of FLNA protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of GPS1 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of H2AFZ protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of HIST1H2AG protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of HIST1H4A protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of HNRNPC protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of ISG15 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of ISYNA1 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of ITGAV protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of LDHB protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of LMNA protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of LMNB2 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of MAP4 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of MATR3 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of MX1 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of NFKB2 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of PPL protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of PRAF2 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of PREX1 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of PRSS8 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of REEP5 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of RPL38 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of S100A16 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of S100A8 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of SDHB protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of SLK protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of SRPR protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of STAT1 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of TNKS1BP1 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of TOP2B protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of TTC9C protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of UBE2L6 protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of UBTF protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of UGDH protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in decreased expression of VCL protein] decreases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of ACY1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of ANKRD36B protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of APRT protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of ARMC10 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of CANX protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of CBX5 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of CD9 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of CLDN1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of CNPY2 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of COMTD1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of CRIP1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of EFHD1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of ELOVL1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of EPHX2 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of ESR2 protein] increases expression
/ increases reaction
protein 20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of FGFR2 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of GIPC1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of GOT2 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of H1F0 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1B protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1C protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1E protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2AB protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2AG protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2BN protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of HIST1H4A protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of HNRNPA2B1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of HNRNPC protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of HNRNPUL2 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of HSD17B8 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of HSPA9 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of ISYNA1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of KIAA0753 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of KIAA1107 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of KRT18 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of KRT19 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of KRT8 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of LAMP2 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of LMNA protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of LYRM7 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of MATR3 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of METTL7A protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of MGP protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of MUC1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of NPM1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of NUMA1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of PIP protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of PRMT1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of PTGR2 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of PYGB protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of RAB18 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of REEP5 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of RNMTL1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of RNPEP protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of S100A9 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of SEPHS1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of SLC9A3R1 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of TFRC protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of TP53I3 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of TRMT112 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 promotes the reaction [Genistein results in increased expression of VPS24 protein] increases expression
/ increases reaction
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) ESR2 protein affects the susceptibility to Genistein affects response to substance
protein 17275032
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Genistein binds to and results in increased activity of ESR2 protein affects binding
/ increases activity
protein 9751507
11502892
11861976
12547825
12765243
15084758
15937998
16076101
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Genistein binds to ESR2 protein affects binding
protein 10964929
11368622
11518614
12224631
15887952
16506809
16566672
19913605
20160136
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) [Genistein binds to ESR2 protein] which binds to NCOA2 protein affects binding
protein 15123288
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) [Genistein co-treated with ESR2 protein] results in decreased expression of EGFR mRNA affects cotreatment
/ decreases expression
protein 19347870
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) [Genistein co-treated with ESR2 protein] results in decreased expression of EGFR protein affects cotreatment
/ decreases expression
protein 19347870
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) [Genistein co-treated with ESR2 protein] results in increased expression of BGLAP mRNA affects cotreatment
/ increases expression
protein 19347870
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) [Genistein co-treated with ESR2 protein] results in increased expression of LTF mRNA affects cotreatment
/ increases expression
protein 21783566
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) [Genistein co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA affects cotreatment
/ increases expression
protein 19347870
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) [Genistein co-treated with ESR2] results in increased expression of BSP mRNA affects cotreatment
/ increases expression
19347870
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Genistein inhibits the reaction [Estradiol binds to ESR2 protein] affects binding
/ decreases reaction
protein 9751507
10964929
11368622
16566672
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Genistein promotes the reaction [ESR2 protein binds to NCOA1 protein] affects binding
/ increases reaction
protein 10964929
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Genistein promotes the reaction [ESR2 protein binds to NCOA2 protein] affects binding
/ increases reaction
protein 10964929
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Genistein promotes the reaction [Estradiol results in increased activity of ESR2 protein] increases activity
/ increases reaction
protein 16118406
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Genistein results in decreased expression of ESR2 mRNA decreases expression
mRNA 15968319
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Genistein results in decreased expression of ESR2 protein decreases expression
protein 20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Genistein results in increased activity of ESR2 protein increases activity
protein 16118406
17132221
18937077
18955141
19161236
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Genistein results in increased activity of ESR2 protein alternative form increases activity
protein 17266178
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Genistein results in increased expression of ESR2 mRNA increases expression
mRNA 16033089
16596234
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Genistein results in increased expression of ESR2 mRNA alternative form increases expression
mRNA 16596234
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Genistein results in increased expression of ESR2 protein increases expression
protein 16033089
20884965
D019833 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) Methoxychlor metabolite inhibits the reaction [Genistein binds to and results in increased activity of ESR2 protein] affects binding
/ decreases reaction
/ increases activity
protein 11861976
D019833 2101 ESRRA
ERR1
ERRa
ERRalpha
ESRL1
NR3B1
estrogen-related receptor alpha Genistein binds to and results in increased activity of ESRRA protein affects binding
/ increases activity
protein 14638870
15955695
D019833 2101 ESRRA
ERR1
ERRa
ERRalpha
ESRL1
NR3B1
estrogen-related receptor alpha Genistein binds to and results in increased activity of ESRRA protein mutant form affects binding
/ increases activity
protein 14638870
D019833 2101 ESRRA
ERR1
ERRa
ERRalpha
ESRL1
NR3B1
estrogen-related receptor alpha Genistein results in increased expression of ESRRA mRNA increases expression
mRNA 16399490
23019147
D019833 2103 ESRRB
DFNB35
ERR2
ERRb
ESRL2
NR3B2
estrogen-related receptor beta Genistein binds to and results in increased activity of ESRRB protein affects binding
/ increases activity
protein 14638870
D019833 2103 ESRRB
DFNB35
ERR2
ERRb
ESRL2
NR3B2
estrogen-related receptor beta Genistein promotes the reaction [ESRRB protein binds to PNRC1 protein] affects binding
/ increases reaction
protein 14638870
D019833 2104 ESRRG
ERR3
ERRgamma
NR3B3
estrogen-related receptor gamma Genistein promotes the reaction [ESRRG protein binds to PNRC1 protein] affects binding
/ increases reaction
protein 14638870
D019833 55224 ETNK2
EKI2
HMFT1716
ethanolamine kinase 2 (EC:2.7.1.82) Genistein results in increased expression of ETNK2 mRNA increases expression
mRNA 19371625
D019833 2114 ETS2
ETS2IT1
v-ets avian erythroblastosis virus E26 oncogene homolog 2 Genistein results in decreased expression of ETS2 mRNA decreases expression
mRNA 16474171
D019833 2137 EXTL3
BOTV
EXTL1L
EXTR1
REGR
RPR
exostosin-like glycosyltransferase 3 (EC:2.4.1.223) Genistein results in decreased expression of EXTL3 mRNA decreases expression
mRNA 16705744
D019833 9415 FADS2
D6D
DES6
FADSD6
LLCDL2
SLL0262
TU13
fatty acid desaturase 2 (EC:1.14.19.-) Genistein results in decreased expression of FADS2 mRNA decreases expression
mRNA 20816778
D019833 399665 FAM102A
C9orf132
EEIG1
SYM-3A
bA203J24.7
family with sequence similarity 102, member A Genistein results in increased expression of FAM102A mRNA increases expression
mRNA 14605097
D019833 11170 FAM107A
DRR1
TU3A
family with sequence similarity 107, member A Genistein results in decreased expression of FAM107A mRNA decreases expression
mRNA 19371625
D019833 116224 FAM122A
C9orf42
family with sequence similarity 122A Genistein results in increased expression of FAM122A mRNA increases expression
mRNA 18847459
D019833 116496 FAM129A
C1orf24
NIBAN
family with sequence similarity 129, member A ESR1 promotes the reaction [Genistein results in increased expression of FAM129A protein] increases expression
/ increases reaction
protein 20884965
D019833 116496 FAM129A
C1orf24
NIBAN
family with sequence similarity 129, member A Genistein results in increased expression of FAM129A protein increases expression
protein 20884965
D019833 23201 FAM168A
KIAA0280
TCRP1
family with sequence similarity 168, member A Genistein results in decreased expression of FAM168A mRNA decreases expression
mRNA 16705744
D019833 84331 FAM195A
C16orf14
c349E10.1
family with sequence similarity 195, member A Genistein results in increased expression of FAM195A mRNA increases expression
mRNA 23019147
D019833 131583 FAM43A
family with sequence similarity 43, member A Genistein results in increased expression of FAM43A mRNA increases expression
mRNA 23019147
D019833 81610 FAM83D
C20orf129
CHICA
dJ616B8.3
family with sequence similarity 83, member D Genistein results in increased expression of FAM83D mRNA increases expression
mRNA 20884965
D019833 157638 FAM84B
BCMP101
NSE2
family with sequence similarity 84, member B Genistein results in decreased expression of FAM84B mRNA decreases expression
mRNA 23019147
D019833 2176 FANCC
FA3
FAC
FACC
Fanconi anemia, complementation group C Genistein results in decreased expression of FANCC mRNA decreases expression
mRNA 16705744
D019833 55215 FANCI
KIAA1794
Fanconi anemia, complementation group I Genistein results in increased expression of FANCI mRNA increases expression
mRNA 16474171
D019833 10160 FARP1
CDEP
PLEKHC2
PPP1R75
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) Genistein results in increased expression of FARP1 mRNA increases expression
mRNA 20884965
D019833 2192 FBLN1
FBLN
FIBL1
fibulin 1 Genistein results in increased expression of FBLN1 mRNA increases expression
mRNA 23019147
D019833 2200 FBN1
ACMICD
ECTOL1
FBN
GPHYSD2
MASS
MFS1
OCTD
SGS
SSKS
WMS
WMS2
fibrillin 1 Genistein results in decreased expression of FBN1 mRNA decreases expression
mRNA 20706672
D019833 2201 FBN2
CCA
DA9
fibrillin 2 Genistein results in decreased expression of FBN2 mRNA decreases expression
mRNA 20706672
D019833 114907 FBXO32
Fbx32
MAFbx
F-box protein 32 Genistein results in increased expression of FBXO32 mRNA increases expression
mRNA 16474171
D019833 26271 FBXO5
EMI1
FBX5
Fbxo31
F-box protein 5 Genistein results in increased expression of FBXO5 mRNA increases expression
mRNA 16474171
D019833 2237 FEN1
FEN-1
MF1
RAD2
flap structure-specific endonuclease 1 Genistein results in increased expression of FEN1 mRNA increases expression
mRNA 16474171
D019833 2246 FGF1
AFGF
ECGF
ECGF-beta
ECGFA
ECGFB
FGF-1
FGF-alpha
FGFA
GLIO703
HBGF-1
HBGF1
fibroblast growth factor 1 (acidic) Genistein results in decreased expression of FGF1 mRNA decreases expression
mRNA 20706672
D019833 2263 FGFR2
BBDS
BEK
BFR-1
CD332
CEK3
CFD1
ECT1
JWS
K-SAM
KGFR
TK14
TK25
fibroblast growth factor receptor 2 (EC:2.7.10.1) ESR2 promotes the reaction [Genistein results in increased expression of FGFR2 protein] increases expression
/ increases reaction
protein 20884965
D019833 2263 FGFR2
BBDS
BEK
BFR-1
CD332
CEK3
CFD1
ECT1
JWS
K-SAM
KGFR
TK14
TK25
fibroblast growth factor receptor 2 (EC:2.7.10.1) Genistein results in decreased expression of FGFR2 mRNA decreases expression
mRNA 23019147
D019833 2263 FGFR2
BBDS
BEK
BFR-1
CD332
CEK3
CFD1
ECT1
JWS
K-SAM
KGFR
TK14
TK25
fibroblast growth factor receptor 2 (EC:2.7.10.1) Genistein results in increased expression of FGFR2 protein increases expression
protein 20884965
D019833 2274 FHL2
AAG11
DRAL
FHL-2
SLIM-3
SLIM3
four and a half LIM domains 2 ESR2 promotes the reaction [Genistein results in decreased expression of FHL2 protein] decreases expression
/ increases reaction
protein 20884965
D019833 2274 FHL2
AAG11
DRAL
FHL-2
SLIM-3
SLIM3
four and a half LIM domains 2 Genistein results in decreased expression of FHL2 mRNA decreases expression
mRNA 20884965
D019833 2274 FHL2
AAG11
DRAL
FHL-2
SLIM-3
SLIM3
four and a half LIM domains 2 Genistein results in decreased expression of FHL2 protein decreases expression
protein 20884965
D019833 2274 FHL2
AAG11
DRAL
FHL-2
SLIM-3
SLIM3
four and a half LIM domains 2 Genistein results in increased expression of FHL2 mRNA increases expression
mRNA 23019147
D019833 2288 FKBP4
FKBP51
FKBP52
FKBP59
HBI
Hsp56
PPIase
p52
FK506 binding protein 4, 59kDa (EC:5.2.1.8) Genistein results in increased expression of FKBP4 mRNA increases expression
mRNA 16474171
D019833 2316 FLNA
ABP-280
ABPX
CSBS
CVD1
FLN
FLN-A
FLN1
FMD
MNS
NHBP
OPD
OPD1
OPD2
XLVD
XMVD
filamin A, alpha ESR2 promotes the reaction [Genistein results in decreased expression of FLNA protein] decreases expression
/ increases reaction
protein 20884965
D019833 2316 FLNA
ABP-280
ABPX
CSBS
CVD1
FLN
FLN-A
FLN1
FMD
MNS
NHBP
OPD
OPD1
OPD2
XLVD
XMVD
filamin A, alpha Genistein results in decreased expression of FLNA protein decreases expression
protein 20884965
D019833 56776 FMN2
formin 2 [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of FMN2 mRNA affects cotreatment
/ increases expression
mRNA 16963248
D019833 252995 FNDC5
FRCP2
irisin
fibronectin type III domain containing 5 Genistein results in decreased expression of FNDC5 mRNA decreases expression
mRNA 19371625
D019833 2348 FOLR1
FBP
FOLR
folate receptor 1 (adult) Genistein results in decreased expression of FOLR1 mRNA decreases expression
mRNA 19371625
D019833 2353 FOS
AP-1
C-FOS
p55
FBJ murine osteosarcoma viral oncogene homolog 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased expression of FOS mRNA] decreases reaction
/ increases expression
mRNA 15090535
D019833 2353 FOS
AP-1
C-FOS
p55
FBJ murine osteosarcoma viral oncogene homolog AG 1879 inhibits the reaction [Genistein results in increased expression of FOS protein] decreases reaction
/ increases expression
protein 15090535
D019833 2353 FOS
AP-1
C-FOS
p55
FBJ murine osteosarcoma viral oncogene homolog Cycloheximide inhibits the reaction [Genistein results in increased expression of FOS protein] decreases reaction
/ increases expression
protein 15090535
D019833 2353 FOS
AP-1
C-FOS
p55
FBJ murine osteosarcoma viral oncogene homolog Genistein results in increased expression of FOS mRNA increases expression
mRNA 15090535
23019147
D019833 2353 FOS
AP-1
C-FOS
p55
FBJ murine osteosarcoma viral oncogene homolog Genistein results in increased expression of FOS protein increases expression
protein 15090535
D019833 2353 FOS
AP-1
C-FOS
p55
FBJ murine osteosarcoma viral oncogene homolog GPER1 protein affects the reaction [Genistein results in increased expression of FOS protein] affects reaction
/ increases expression
protein 15090535
D019833 2353 FOS
AP-1
C-FOS
p55
FBJ murine osteosarcoma viral oncogene homolog MAPK3 gene mutant form inhibits the reaction [Genistein results in increased expression of FOS protein] decreases reaction
/ increases expression
protein 15090535
D019833 2353 FOS
AP-1
C-FOS
p55
FBJ murine osteosarcoma viral oncogene homolog MEN1 protein inhibits the reaction [Genistein results in increased expression of FOS mRNA] decreases reaction
/ increases expression
mRNA 15090535
D019833 2353 FOS
AP-1
C-FOS
p55
FBJ murine osteosarcoma viral oncogene homolog Pertussis Toxin inhibits the reaction [Genistein results in increased expression of FOS protein] decreases reaction
/ increases expression
protein 15090535
D019833 2353 FOS
AP-1
C-FOS
p55
FBJ murine osteosarcoma viral oncogene homolog tyrphostin AG 1478 inhibits the reaction [Genistein results in increased expression of FOS protein] decreases reaction
/ increases expression
protein 15090535
D019833 2297 FOXD1
FKHL8
FREAC4
forkhead box D1 Genistein results in increased expression of FOXD1 mRNA increases expression
mRNA 19371625
D019833 2302 FOXJ1
FKHL13
HFH-4
HFH4
forkhead box J1 Genistein results in decreased expression of FOXJ1 mRNA decreases expression
mRNA 16705744
19371625
D019833 2309 FOXO3
AF6q21
FKHRL1
FKHRL1P2
FOXO2
FOXO3A
forkhead box O3 Genistein affects the expression of FOXO3 mRNA affects expression
mRNA 18431742
D019833 2309 FOXO3
AF6q21
FKHRL1
FKHRL1P2
FOXO2
FOXO3A
forkhead box O3 Genistein affects the expression of FOXO3 protein affects expression
protein 18431742
D019833 2309 FOXO3
AF6q21
FKHRL1
FKHRL1P2
FOXO2
FOXO3A
forkhead box O3 Genistein affects the localization of FOXO3 protein affects localization
protein 18431742
D019833 2309 FOXO3
AF6q21
FKHRL1
FKHRL1P2
FOXO2
FOXO3A
forkhead box O3 Genistein inhibits the reaction [HIST3H3 protein modified form binds to FOXO3 promoter] affects binding
/ decreases reaction
promoter 18431742
D019833 2309 FOXO3
AF6q21
FKHRL1
FKHRL1P2
FOXO2
FOXO3A
forkhead box O3 Genistein inhibits the reaction [SIRT1 protein binds to FOXO3 promoter] affects binding
/ decreases reaction
promoter 18431742
D019833 2309 FOXO3
AF6q21
FKHRL1
FKHRL1P2
FOXO2
FOXO3A
forkhead box O3 Genistein results in decreased phosphorylation of FOXO3 protein decreases phosphorylation
protein 18431742
D019833 2309 FOXO3
AF6q21
FKHRL1
FKHRL1P2
FOXO2
FOXO3A
forkhead box O3 [[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased activity of FOXO3 protein decreases activity
/ increases activity
/ increases expression
protein 18431742
D019833 2525 FUT3
CD174
FT3B
FucT-III
LE
Les
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (EC:2.4.1.65) Genistein results in increased expression of FUT3 mRNA increases expression
mRNA 23019147
D019833 2527 FUT5
FUC-TV
fucosyltransferase 5 (alpha (1,3) fucosyltransferase) (EC:2.4.1.65) Genistein results in increased expression of FUT5 mRNA increases expression
mRNA 23019147
D019833 7976 FZD3
Fz-3
frizzled family receptor 3 Genistein results in increased expression of FZD3 mRNA increases expression
mRNA 18847459
D019833 7855 FZD5
C2orf31
HFZ5
frizzled family receptor 5 Genistein results in increased expression of FZD5 mRNA increases expression
mRNA 23019147
D019833 50486 G0S2
RP1-28O10.2
G0/G1switch 2 Genistein results in increased expression of G0S2 mRNA increases expression
mRNA 19371625
23019147
D019833 2548 GAA
LYAG
glucosidase, alpha; acid (EC:3.2.1.20) Genistein results in increased expression of GAA mRNA increases expression
mRNA 16705744
D019833 1647 GADD45A
DDIT1
GADD45
growth arrest and DNA-damage-inducible, alpha Genistein results in decreased expression of GADD45A mRNA decreases expression
mRNA 16474171
D019833 10912 GADD45G
CR6
DDIT2
GADD45gamma
GRP17
growth arrest and DNA-damage-inducible, gamma Genistein results in increased expression of GADD45G mRNA increases expression
mRNA 23019147
D019833 8693 GALNT4
GALNAC-T4
GALNACT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4) (EC:2.4.1.41) Genistein results in increased expression of GALNT4 mRNA increases expression
mRNA 19371625
D019833 8811 GALR2
GAL2-R
GALNR2
GALR-2
galanin receptor 2 Genistein results in decreased expression of GALR2 mRNA decreases expression
mRNA 19371625
D019833 2621 GAS6
AXLLG
AXSF
growth arrest-specific 6 Genistein results in increased expression of GAS6 mRNA increases expression
mRNA 23019147
D019833 2633 GBP1
guanylate binding protein 1, interferon-inducible Genistein results in decreased expression of GBP1 mRNA decreases expression
mRNA 16705744
20884965
D019833 2634 GBP2
guanylate binding protein 2, interferon-inducible Genistein results in decreased expression of GBP2 mRNA decreases expression
mRNA 20884965
D019833 9615 GDA
CYPIN
GUANASE
NEDASIN
guanine deaminase (EC:3.5.4.3) Genistein results in decreased expression of GDA mRNA decreases expression
mRNA 23019147
D019833 9518 GDF15
GDF-15
MIC-1
MIC1
NAG-1
PDF
PLAB
PTGFB
growth differentiation factor 15 Genistein results in decreased expression of GDF15 mRNA decreases expression
mRNA 20884965
D019833 81544 GDPD5
GDE2
PP1665
glycerophosphodiester phosphodiesterase domain containing 5 Genistein results in increased expression of GDPD5 mRNA increases expression
mRNA 19371625
23019147
D019833 2674 GFRA1
GDNFR
GDNFRA
GFR-ALPHA-1
RET1L
RETL1
TRNR1
GDNF family receptor alpha 1 Genistein results in increased expression of GFRA1 mRNA increases expression
mRNA 16474171
D019833 8836 GGH
GH
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) (EC:3.4.19.9) Genistein results in increased expression of GGH mRNA increases expression
mRNA 16474171
D019833 9837 GINS1
PSF1
GINS complex subunit 1 (Psf1 homolog) Genistein results in increased expression of GINS1 mRNA increases expression
mRNA 16474171
D019833 51659 GINS2
HSPC037
PSF2
Pfs2
GINS complex subunit 2 (Psf2 homolog) Genistein results in increased expression of GINS2 mRNA increases expression
mRNA 16474171
D019833 10755 GIPC1
C19orf3
GIPC
GLUT1CBP
Hs.6454
IIP-1
NIP
RGS19IP1
SEMCAP
SYNECTIIN
SYNECTIN
TIP-2
GIPC PDZ domain containing family, member 1 ESR2 promotes the reaction [Genistein results in increased expression of GIPC1 protein] increases expression
/ increases reaction
protein 20884965
D019833 10755 GIPC1
C19orf3
GIPC
GLUT1CBP
Hs.6454
IIP-1
NIP
RGS19IP1
SEMCAP
SYNECTIIN
SYNECTIN
TIP-2
GIPC PDZ domain containing family, member 1 Genistein results in increased expression of GIPC1 protein increases expression
protein 20884965
D019833 2731 GLDC
GCE
GCSP
HYGN1
glycine dehydrogenase (decarboxylating) (EC:1.4.4.2) Genistein results in increased expression of GLDC mRNA increases expression
mRNA 20884965
D019833 2741 GLRA1
HKPX1
STHE
glycine receptor, alpha 1 Genistein results in decreased activity of GLRA1 protein decreases activity
protein 20719748
D019833 2741 GLRA1
HKPX1
STHE
glycine receptor, alpha 1 Strychnine promotes the reaction [Genistein results in decreased activity of GLRA1 protein] decreases activity
/ increases reaction
protein 20719748
D019833 51022 GLRX2
CGI-133
GRX2
glutaredoxin 2 Genistein results in increased expression of GLRX2 mRNA increases expression
mRNA 19371625
D019833 2752 GLUL
GLNS
GS
PIG43
PIG59
glutamate-ammonia ligase (EC:4.1.1.15 6.3.1.2) Genistein results in decreased expression of GLUL mRNA decreases expression
mRNA 16705744
D019833 51053 GMNN
Gem
geminin, DNA replication inhibitor Genistein results in increased expression of GMNN mRNA increases expression
mRNA 15256057
16474171
D019833 2783 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2 Genistein results in decreased expression of GNB2 mRNA decreases expression
mRNA 16705744
D019833 2788 GNG7
guanine nucleotide binding protein (G protein), gamma 7 Genistein results in increased expression of GNG7 mRNA increases expression
mRNA 18847459
D019833 2806 GOT2
KAT4
KATIV
mitAAT
glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7) ESR2 promotes the reaction [Genistein results in increased expression of GOT2 protein] increases expression
/ increases reaction
protein 20884965
D019833 2806 GOT2
KAT4
KATIV
mitAAT
glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7) Genistein results in increased expression of GOT2 protein increases expression
protein 20884965
D019833 2852 GPER1
CEPR
CMKRL2
DRY12
FEG-1
GPCR-Br
GPER
GPR30
LERGU
LERGU2
LyGPR
G protein-coupled estrogen receptor 1 Genistein binds to and results in increased activity of GPER1 protein affects binding
/ increases activity
protein 17088055
D019833 2852 GPER1
CEPR
CMKRL2
DRY12
FEG-1
GPCR-Br
GPER
GPR30
LERGU
LERGU2
LyGPR
G protein-coupled estrogen receptor 1 GPER1 protein affects the reaction [Genistein results in increased expression of FOS protein] affects reaction
/ increases expression
protein 15090535
D019833 9289 GPR56
BFPP
TM7LN4
TM7XN1
G protein-coupled receptor 56 Genistein results in increased expression of GPR56 mRNA increases expression
mRNA 23019147
D019833 9052 GPRC5A
GPCR5A
RAI3
RAIG1
G protein-coupled receptor, family C, group 5, member A Genistein results in decreased expression of GPRC5A mRNA decreases expression
mRNA 16474171
D019833 2873 GPS1
COPS1
CSN1
G protein pathway suppressor 1 ESR2 promotes the reaction [Genistein results in decreased expression of GPS1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 2873 GPS1
COPS1
CSN1
G protein pathway suppressor 1 Genistein results in decreased expression of GPS1 protein decreases expression
protein 20884965
D019833 26086 GPSM1
AGS3
G-protein signaling modulator 1 Genistein results in increased expression of GPSM1 mRNA increases expression
mRNA 23019147
D019833 2876 GPX1
GPXD
GSHPX1
glutathione peroxidase 1 (EC:1.11.1.9) Genistein results in increased expression of GPX1 mRNA increases expression
mRNA 18686095
D019833 2885 GRB2
ASH
EGFRBP-GRB2
Grb3-3
MST084
MSTP084
NCKAP2
growth factor receptor-bound protein 2 Genistein results in decreased expression of GRB2 mRNA decreases expression
mRNA 16705744
D019833 2885 GRB2
ASH
EGFRBP-GRB2
Grb3-3
MST084
MSTP084
NCKAP2
growth factor receptor-bound protein 2 Genistein results in increased expression of GRB2 mRNA increases expression
mRNA 20884965
D019833 9687 GREB1
growth regulation by estrogen in breast cancer 1 Genistein promotes the reaction [ESR1 protein binds to GREB1 promoter] affects binding
/ increases reaction
promoter 23019147
D019833 9687 GREB1
growth regulation by estrogen in breast cancer 1 Genistein results in increased expression of GREB1 mRNA increases expression
mRNA 16474171
19371625
23019147
D019833 2932 GSK3B
glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) Genistein results in decreased phosphorylation of GSK3B protein decreases phosphorylation
protein 18431742
D019833 2936 GSR
glutathione reductase (EC:1.8.1.7) Genistein results in decreased expression of GSR mRNA decreases expression
mRNA 16705744
D019833 2937 GSS
GSHS
glutathione synthetase (EC:6.3.2.3) Genistein results in decreased expression of GSS mRNA decreases expression
mRNA 16705744
D019833 2962 GTF2F1
BTF4
RAP74
TF2F1
TFIIF
general transcription factor IIF, polypeptide 1, 74kDa Genistein results in decreased expression of GTF2F1 mRNA decreases expression
mRNA 16705744
D019833 51512 GTSE1
B99
G-2 and S-phase expressed 1 Genistein affects the expression of GTSE1 mRNA affects expression
mRNA 18847459
D019833 3001 GZMA
CTLA3
HFSP
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) (EC:3.4.21.78) Genistein results in increased expression of GZMA mRNA increases expression
mRNA 15256057
D019833 3005 H1F0
H10
H1FV
H1 histone family, member 0 ESR2 promotes the reaction [Genistein results in increased expression of H1F0 protein] increases expression
/ increases reaction
protein 20884965
D019833 3005 H1F0
H10
H1FV
H1 histone family, member 0 Genistein results in increased expression of H1F0 protein increases expression
protein 20884965
D019833 3014 H2AFX
H2A.X
H2A/X
H2AX
H2A histone family, member X Genistein results in increased expression of H2AFX mRNA increases expression
mRNA 16474171
D019833 3015 H2AFZ
H2A.Z-1
H2A.z
H2A/z
H2AZ
H2A histone family, member Z ESR2 promotes the reaction [Genistein results in decreased expression of H2AFZ protein] decreases expression
/ increases reaction
protein 20884965
D019833 3015 H2AFZ
H2A.Z-1
H2A.z
H2A/z
H2AZ
H2A histone family, member Z Genistein results in decreased expression of H2AFZ protein decreases expression
protein 20884965
D019833 3015 H2AFZ
H2A.Z-1
H2A.z
H2A/z
H2AZ
H2A histone family, member Z Genistein results in increased expression of H2AFZ mRNA increases expression
mRNA 16474171
D019833 3033 HADH
HAD
HADH1
HADHSC
HCDH
HHF4
MSCHAD
SCHAD
hydroxyacyl-CoA dehydrogenase (EC:1.1.1.35) Genistein results in increased expression of HADH mRNA increases expression
mRNA 16474171
D019833 3036 HAS1
HAS
hyaluronan synthase 1 (EC:2.4.1.212) Genistein results in decreased expression of HAS1 mRNA decreases expression
mRNA 20706672
D019833 26959 HBP1
HMG-box transcription factor 1 Genistein results in decreased expression of HBP1 mRNA decreases expression
mRNA 23019147
D019833 54985 HCFC1R1
HPIP
host cell factor C1 regulator 1 (XPO1 dependent) Genistein results in increased expression of HCFC1R1 mRNA increases expression
mRNA 18847459
D019833 610 HCN2
BCNG-2
BCNG2
HAC-1
hyperpolarization activated cyclic nucleotide-gated potassium channel 2 Genistein results in increased expression of HCN2 mRNA increases expression
mRNA 23019147
D019833 10870 HCST
DAP10
KAP10
PIK3AP
hematopoietic cell signal transducer Genistein results in decreased expression of HCST mRNA decreases expression
mRNA 18847459
D019833 63897 HEATR6
ABC1
HEAT repeat containing 6 Genistein results in increased expression of HEATR6 mRNA increases expression
mRNA 20884965
D019833 3280 HES1
HES-1
HHL
HRY
bHLHb39
hes family bHLH transcription factor 1 Genistein results in decreased expression of HES1 mRNA decreases expression
mRNA 23019147
D019833 54626 HES2
bHLHb40
hes family bHLH transcription factor 2 Genistein results in increased expression of HES2 mRNA increases expression
mRNA 19371625
23019147
D019833 284004 HEXDC
hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing (EC:3.2.1.52) Genistein results in increased expression of HEXDC mRNA increases expression
mRNA 23019147
D019833 3091 HIF1A
HIF-1A
HIF-1alpha
HIF1
HIF1-ALPHA
MOP1
PASD8
bHLHe78
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Genistein affects the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]] affects binding
/ affects reaction
/ increases reaction
protein 10939628
D019833 3091 HIF1A
HIF-1A
HIF-1alpha
HIF1
HIF1-ALPHA
MOP1
PASD8
bHLHe78
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Genistein affects the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]] affects binding
/ affects reaction
/ increases reaction
protein 10939628
D019833 3009 HIST1H1B
H1
H1.5
H1B
H1F5
H1s-3
histone cluster 1, H1b ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1B protein] increases expression
/ increases reaction
protein 20884965
D019833 3009 HIST1H1B
H1
H1.5
H1B
H1F5
H1s-3
histone cluster 1, H1b Genistein results in increased expression of HIST1H1B protein increases expression
protein 20884965
D019833 3006 HIST1H1C
H1.2
H1C
H1F2
H1s-1
histone cluster 1, H1c ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1C protein] increases expression
/ increases reaction
protein 20884965
D019833 3006 HIST1H1C
H1.2
H1C
H1F2
H1s-1
histone cluster 1, H1c Genistein results in increased expression of HIST1H1C protein increases expression
protein 20884965
D019833 3008 HIST1H1E
H1.4
H1E
H1F4
H1s-4
dJ221C16.5
histone cluster 1, H1e ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1E protein] increases expression
/ increases reaction
protein 20884965
D019833 3008 HIST1H1E
H1.4
H1E
H1F4
H1s-4
dJ221C16.5
histone cluster 1, H1e Genistein results in increased expression of HIST1H1E protein increases expression
protein 20884965
D019833 8335 HIST1H2AB
H2A/m
H2AFM
histone cluster 1, H2ab ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2AB protein] increases expression
/ increases reaction
protein 20884965
D019833 8335 HIST1H2AB
H2A/m
H2AFM
histone cluster 1, H2ab Genistein results in increased expression of HIST1H2AB protein increases expression
protein 20884965
D019833 8334 HIST1H2AC
H2A/l
H2AFL
dJ221C16.4
histone cluster 1, H2ac Genistein results in decreased expression of HIST1H2AC mRNA decreases expression
mRNA 16474171
D019833 8969 HIST1H2AG
H2A.1b
H2A/p
H2AFP
H2AG
pH2A/f
histone cluster 1, H2ag ESR2 promotes the reaction [Genistein results in decreased expression of HIST1H2AG protein] decreases expression
/ increases reaction
protein 20884965
D019833 8969 HIST1H2AG
H2A.1b
H2A/p
H2AFP
H2AG
pH2A/f
histone cluster 1, H2ag ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2AG protein] increases expression
/ increases reaction
protein 20884965
D019833 8969 HIST1H2AG
H2A.1b
H2A/p
H2AFP
H2AG
pH2A/f
histone cluster 1, H2ag Genistein results in decreased expression of HIST1H2AG protein decreases expression
protein 20884965
D019833 8969 HIST1H2AG
H2A.1b
H2A/p
H2AFP
H2AG
pH2A/f
histone cluster 1, H2ag Genistein results in increased expression of HIST1H2AG protein increases expression
protein 20884965
D019833 3017 HIST1H2BD
H2B.1B
H2B/b
H2BFB
HIRIP2
dJ221C16.6
histone cluster 1, H2bd Genistein results in decreased expression of HIST1H2BD mRNA decreases expression
mRNA 19371625
D019833 8341 HIST1H2BN
H2B/d
H2BFD
histone cluster 1, H2bn ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2BN protein] increases expression
/ increases reaction
protein 20884965
D019833 8341 HIST1H2BN
H2B/d
H2BFD
histone cluster 1, H2bn Genistein results in increased expression of HIST1H2BN protein increases expression
protein 20884965
D019833 8359 HIST1H4A
H4FA
histone cluster 1, H4a ESR2 promotes the reaction [Genistein results in decreased expression of HIST1H4A protein] decreases expression
/ increases reaction
protein 20884965
D019833 8359 HIST1H4A
H4FA
histone cluster 1, H4a ESR2 promotes the reaction [Genistein results in increased expression of HIST1H4A protein] increases expression
/ increases reaction
protein 20884965
D019833 8359 HIST1H4A
H4FA
histone cluster 1, H4a Genistein results in decreased expression of HIST1H4A protein decreases expression
protein 20884965
D019833 8359 HIST1H4A
H4FA
histone cluster 1, H4a Genistein results in increased expression of HIST1H4A protein increases expression
protein 20884965
D019833 8349 HIST2H2BE
GL105
H2B
H2B.1
H2BFQ
H2BGL105
H2BQ
histone cluster 2, H2be Genistein results in decreased expression of HIST2H2BE mRNA decreases expression
mRNA 16474171
D019833 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 Genistein inhibits the reaction [HIST3H3 protein modified form binds to CYLD promoter] affects binding
/ decreases reaction
protein 18431742
D019833 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 Genistein inhibits the reaction [HIST3H3 protein modified form binds to FOXO3 promoter] affects binding
/ decreases reaction
protein 18431742
D019833 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 Genistein inhibits the reaction [HIST3H3 protein modified form binds to PTEN promoter] affects binding
/ decreases reaction
protein 18431742
D019833 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 Genistein inhibits the reaction [HIST3H3 protein modified form binds to TP53 promoter] affects binding
/ decreases reaction
protein 18431742
D019833 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 [Genistein results in decreased activity of SIRT1 protein] which results in decreased acetylation of HIST3H3 protein decreases acetylation
/ decreases activity
protein 18431742
D019833 8290 HIST3H3
H3.4
H3/g
H3FT
H3t
histone cluster 3, H3 Genistein results in increased expression of HIST3H3 protein modified form increases expression
protein 19221000
D019833 3096 HIVEP1
CIRIP
CRYBP1
MBP-1
PRDII-BF1
Schnurri-1
ZAS1
ZNF40
ZNF40A
human immunodeficiency virus type I enhancer binding protein 1 Genistein results in increased expression of HIVEP1 mRNA increases expression
mRNA 19371625
D019833 3099 HK2
HKII
HXK2
hexokinase 2 (EC:2.7.1.1) Genistein results in increased expression of HK2 mRNA increases expression
mRNA 23019147
D019833 3122 HLA-DRA
HLA-DRA1
MLRW
major histocompatibility complex, class II, DR alpha Genistein results in decreased expression of HLA-DRA mRNA decreases expression
mRNA 20816778
D019833 81502 HM13
H13
IMP1
IMPAS
IMPAS-1
MSTP086
PSENL3
PSL3
SPP
SPPL1
dJ324O17.1
histocompatibility (minor) 13 Genistein results in decreased expression of HM13 mRNA decreases expression
mRNA 16705744
D019833 3148 HMGB2
HMG2
high mobility group box 2 Genistein results in increased expression of HMGB2 mRNA increases expression
mRNA 16474171
D019833 3155 HMGCL
HL
3-hydroxymethyl-3-methylglutaryl-CoA lyase (EC:4.1.3.4) Genistein results in increased expression of HMGCL mRNA increases expression
mRNA 20884965
D019833 3150 HMGN1
HMG14
high mobility group nucleosome binding domain 1 ESR1 promotes the reaction [Genistein results in decreased expression of HMGN1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 3150 HMGN1
HMG14
high mobility group nucleosome binding domain 1 Genistein results in decreased expression of HMGN1 protein decreases expression
protein 20884965
D019833 3151 HMGN2
HMG17
high mobility group nucleosomal binding domain 2 Genistein results in decreased expression of HMGN2 mRNA decreases expression
mRNA 18847459
19371625
D019833 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Genistein inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA] decreases reaction
/ increases expression
mRNA 9722676
D019833 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Genistein inhibits the reaction [Hemin results in increased expression of HMOX1 mRNA] decreases reaction
/ increases expression
mRNA 9722676
D019833 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Genistein inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA] decreases reaction
/ increases expression
mRNA 9722676
D019833 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Genistein promotes the reaction [Cadmium Chloride results in increased expression of HMOX1 protein] increases expression
/ increases reaction
protein 22659318
D019833 3181 HNRNPA2B1
HNRNPA2
HNRNPB1
HNRPA2
HNRPA2B1
HNRPB1
IBMPFD2
RNPA2
SNRPB1
heterogeneous nuclear ribonucleoprotein A2/B1 ESR2 promotes the reaction [Genistein results in increased expression of HNRNPA2B1 protein] increases expression
/ increases reaction
protein 20884965
D019833 3181 HNRNPA2B1
HNRNPA2
HNRNPB1
HNRPA2
HNRPA2B1
HNRPB1
IBMPFD2
RNPA2
SNRPB1
heterogeneous nuclear ribonucleoprotein A2/B1 Genistein results in increased expression of HNRNPA2B1 protein increases expression
protein 20884965
D019833 3183 HNRNPC
C1
C2
HNRNP
HNRPC
SNRPC
heterogeneous nuclear ribonucleoprotein C (C1/C2) ESR1 promotes the reaction [Genistein results in decreased expression of HNRNPC protein] decreases expression
/ increases reaction
protein 20884965
D019833 3183 HNRNPC
C1
C2
HNRNP
HNRPC
SNRPC
heterogeneous nuclear ribonucleoprotein C (C1/C2) ESR2 promotes the reaction [Genistein results in decreased expression of HNRNPC protein] decreases expression
/ increases reaction
protein 20884965
D019833 3183 HNRNPC
C1
C2
HNRNP
HNRPC
SNRPC
heterogeneous nuclear ribonucleoprotein C (C1/C2) ESR2 promotes the reaction [Genistein results in increased expression of HNRNPC protein] increases expression
/ increases reaction
protein 20884965
D019833 3183 HNRNPC
C1
C2
HNRNP
HNRPC
SNRPC
heterogeneous nuclear ribonucleoprotein C (C1/C2) Genistein results in decreased expression of HNRNPC protein decreases expression
protein 20884965
D019833 3183 HNRNPC
C1
C2
HNRNP
HNRPC
SNRPC
heterogeneous nuclear ribonucleoprotein C (C1/C2) Genistein results in increased expression of HNRNPC protein increases expression
protein 20884965
D019833 221092 HNRNPUL2
HNRPUL2
SAF-A2
heterogeneous nuclear ribonucleoprotein U-like 2 ESR2 promotes the reaction [Genistein results in increased expression of HNRNPUL2 protein] increases expression
/ increases reaction
protein 20884965
D019833 221092 HNRNPUL2
HNRPUL2
SAF-A2
heterogeneous nuclear ribonucleoprotein U-like 2 Genistein results in increased expression of HNRNPUL2 protein increases expression
protein 20884965
D019833 9455 HOMER2
ACPD
CPD
HOMER-2
VESL-2
homer homolog 2 (Drosophila) Genistein results in decreased expression of HOMER2 mRNA decreases expression
mRNA 15378649
D019833 3206 HOXA10
HOX1
HOX1.8
HOX1H
PL
homeobox A10 Genistein results in increased expression of HOXA10 mRNA increases expression
mRNA 16632680
D019833 3206 HOXA10
HOX1
HOX1.8
HOX1H
PL
homeobox A10 Genistein results in increased expression of HOXA10 protein increases expression
protein 16632680
D019833 55806 HR
ALUNC
AU
HSA277165
MUHH
MUHH1
hair growth associated Genistein results in increased expression of HR mRNA increases expression
mRNA 23019147
D019833 3291 HSD11B2
AME
AME1
HSD11K
HSD2
SDR9C3
hydroxysteroid (11-beta) dehydrogenase 2 (EC:1.1.1.146) Genistein results in increased expression of HSD11B2 mRNA increases expression
mRNA 23019147
D019833 3292 HSD17B1
EDH17B2
EDHB17
HSD17
SDR28C1
hydroxysteroid (17-beta) dehydrogenase 1 (EC:1.1.1.62) Genistein results in decreased activity of HSD17B1 protein decreases activity
protein 15876411
D019833 7923 HSD17B8
D6S2245E
FABG
FABGL
H2-KE6
HKE6
KE6
RING2
SDR30C1
dJ1033B10.9
hydroxysteroid (17-beta) dehydrogenase 8 (EC:1.1.1.62 1.1.1.239) ESR2 promotes the reaction [Genistein results in increased expression of HSD17B8 protein] increases expression
/ increases reaction
protein 20884965
D019833 7923 HSD17B8
D6S2245E
FABG
FABGL
H2-KE6
HKE6
KE6
RING2
SDR30C1
dJ1033B10.9
hydroxysteroid (17-beta) dehydrogenase 8 (EC:1.1.1.62 1.1.1.239) Genistein results in increased expression of HSD17B8 protein increases expression
protein 20884965
D019833 3306 HSPA2
HSP70-2
HSP70-3
heat shock 70kDa protein 2 Genistein results in increased expression of HSPA2 mRNA increases expression
mRNA 20884965
D019833 22824 HSPA4L
APG-1
HSPH3
Osp94
heat shock 70kDa protein 4-like Genistein results in increased expression of HSPA4L mRNA increases expression
mRNA 18847459
D019833 3313 HSPA9
CSA
GRP-75
GRP75
HSPA9B
MOT
MOT2
MTHSP75
PBP74
heat shock 70kDa protein 9 (mortalin) ESR2 promotes the reaction [Genistein results in increased expression of HSPA9 protein] increases expression
/ increases reaction
protein 20884965
D019833 3313 HSPA9
CSA
GRP-75
GRP75
HSPA9B
MOT
MOT2
MTHSP75
PBP74
heat shock 70kDa protein 9 (mortalin) Genistein results in increased expression of HSPA9 protein increases expression
protein 20884965
D019833 26353 HSPB8
CMT2L
DHMN2
E2IG1
H11
HMN2
HMN2A
HSP22
heat shock 22kDa protein 8 Genistein results in increased expression of HSPB8 mRNA increases expression
mRNA 23524099
D019833 81888 HYI
HT036
hydroxypyruvate isomerase (putative) (EC:5.3.1.22) Genistein results in decreased expression of HYI mRNA decreases expression
mRNA 16705744
D019833 3397 ID1
ID
bHLHb24
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein Genistein results in decreased expression of ID1 mRNA decreases expression
mRNA 21554132
23019147
D019833 3397 ID1
ID
bHLHb24
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein Genistein results in decreased expression of ID1 protein decreases expression
protein 21554132
D019833 3399 ID3
HEIR-1
bHLHb25
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein Genistein results in decreased expression of ID3 mRNA decreases expression
mRNA 16474171
D019833 3422 IDI1
IPP1
IPPI1
isopentenyl-diphosphate delta isomerase 1 (EC:5.3.3.2) Genistein results in increased expression of IDI1 mRNA increases expression
mRNA 15378649
D019833 389792 IER5L
bA247A12.2
immediate early response 5-like Genistein results in increased expression of IER5L mRNA increases expression
mRNA 23019147
D019833 10410 IFITM3
1-8U
DSPA2b
IP15
interferon induced transmembrane protein 3 Genistein results in decreased expression of IFITM3 mRNA decreases expression
mRNA 19371625
D019833 3458 IFNG
IFG
IFI
interferon, gamma Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL8 mRNA] affects cotreatment
/ decreases reaction
/ increases expression
protein 15779068
D019833 3458 IFNG
IFG
IFI
interferon, gamma Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL8 protein] affects cotreatment
/ decreases reaction
/ increases expression
protein 15779068
D019833 3458 IFNG
IFG
IFI
interferon, gamma Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA] affects cotreatment
/ decreases reaction
/ increases expression
protein 15779068
D019833 3458 IFNG
IFG
IFI
interferon, gamma Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein] affects cotreatment
/ decreases reaction
/ increases expression
protein 15779068
D019833 282618 IFNL1
IL-29
IL29
interferon, lambda 1 Genistein results in increased expression of IFNL1 mRNA increases expression
mRNA 20884965
D019833 7866 IFRD2
IFNRP
SKMc15
SM15
interferon-related developmental regulator 2 [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of IFRD2 mRNA affects cotreatment
/ increases expression
mRNA 16963248
D019833 3479 IGF1
IGF-I
IGF1A
IGFI
insulin-like growth factor 1 (somatomedin C) Genistein results in decreased expression of IGF1 mRNA decreases expression
mRNA 20706672
D019833 3480 IGF1R
CD221
IGFIR
IGFR
JTK13
insulin-like growth factor 1 receptor (EC:2.7.10.1) Genistein results in decreased expression of IGF1R mRNA decreases expression
mRNA 16865672
D019833 3486 IGFBP3
BP-53
IBP3
insulin-like growth factor binding protein 3 [Calcitriol co-treated with Genistein] results in increased expression of IGFBP3 mRNA affects cotreatment
/ increases expression
mRNA 15955619
D019833 3486 IGFBP3
BP-53
IBP3
insulin-like growth factor binding protein 3 Genistein results in decreased expression of IGFBP3 mRNA decreases expression
mRNA 23019147
D019833 3487 IGFBP4
BP-4
HT29-IGFBP
IBP4
IGFBP-4
insulin-like growth factor binding protein 4 Genistein results in increased expression of IGFBP4 mRNA increases expression
mRNA 15757668
16474171
20884965
D019833 93185 IGSF8
CD316
CD81P3
EWI-2
EWI2
KCT-4
LIR-D1
PGRL
immunoglobulin superfamily, member 8 Genistein results in increased expression of IGSF8 mRNA increases expression
mRNA 20884965
D019833 3600 IL15
IL-15
interleukin 15 Genistein results in decreased expression of IL15 mRNA decreases expression
mRNA 20816778
D019833 3552 IL1A
IL-1A
IL1
IL1-ALPHA
IL1F1
interleukin 1, alpha Genistein results in decreased expression of IL1A mRNA decreases expression
mRNA 20706672
D019833 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Genistein inhibits the reaction [IL1B protein results in increased secretion of IL8 protein] decreases reaction
/ increases secretion
protein 18377686
D019833 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Genistein results in decreased expression of IL1B mRNA decreases expression
mRNA 20816778
D019833 7850 IL1R2
CD121b
CDw121b
IL-1R-2
IL-1RT-2
IL-1RT2
IL1R2c
IL1RB
interleukin 1 receptor, type II Genistein results in increased expression of IL1R2 mRNA increases expression
mRNA 23019147
D019833 3566 IL4R
CD124
IL-4RA
IL4RA
interleukin 4 receptor Genistein results in decreased expression of IL4R mRNA decreases expression
mRNA 16705744
D019833 3566 IL4R
CD124
IL-4RA
IL4RA
interleukin 4 receptor Genistein results in increased expression of IL4R mRNA increases expression
mRNA 23019147
D019833 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Genistein results in decreased secretion of IL6 protein decreases secretion
protein 20816778
D019833 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Genistein results in increased expression of IL6 mRNA increases expression
mRNA 18025290
D019833 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Genistein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IL8 mRNA] decreases reaction
/ increases expression
mRNA 21056929
D019833 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Genistein inhibits the reaction [IL1B protein results in increased secretion of IL8 protein] decreases reaction
/ increases secretion
protein 18377686
D019833 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL8 mRNA] affects cotreatment
/ decreases reaction
/ increases expression
mRNA 15779068
D019833 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL8 protein] affects cotreatment
/ decreases reaction
/ increases expression
protein 15779068
D019833 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Genistein results in decreased expression of IL8 mRNA decreases expression
mRNA 21056929
D019833 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Genistein results in increased expression of IL8 mRNA increases expression
mRNA 15257099
D019833 3608 ILF2
NF45
PRO3063
interleukin enhancer binding factor 2 Genistein results in increased expression of ILF2 mRNA increases expression
mRNA 16474171
D019833 3609 ILF3
CBTF
DRBF
DRBP76
MMP4
MPHOSPH4
MPP4
NF-AT-90
NF110
NF110b
NF90
NF90a
NF90b
NFAR
NFAR-1
NFAR2
TCP110
TCP80
interleukin enhancer binding factor 3, 90kDa Genistein results in decreased expression of ILF3 mRNA decreases expression
mRNA 18847459
D019833 3615 IMPDH2
IMPD2
IMPDH-II
IMP (inosine 5'-monophosphate) dehydrogenase 2 (EC:1.1.1.205) Genistein results in increased expression of IMPDH2 mRNA increases expression
mRNA 19371625
D019833 8821 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa (EC:3.1.3.66) Genistein results in decreased expression of INPP4B mRNA decreases expression
mRNA 15378649
D019833 3638 INSIG1
CL-6
CL6
insulin induced gene 1 Genistein results in increased expression of INSIG1 mRNA increases expression
mRNA 18847459
D019833 9670 IPO13
IMP13
KAP13
LGL2
RANBP13
importin 13 Genistein results in increased expression of IPO13 mRNA increases expression
mRNA 19371625
D019833 79711 IPO4
Imp4
importin 4 Genistein results in increased expression of IPO4 mRNA increases expression
mRNA 23019147
D019833 10788 IQGAP2
IQ motif containing GTPase activating protein 2 Genistein results in decreased expression of IQGAP2 mRNA decreases expression
mRNA 15378649
D019833 26145 IRF2BP1
interferon regulatory factor 2 binding protein 1 [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of IRF2BP1 mRNA affects cotreatment
/ increases expression
mRNA 16963248
D019833 3665 IRF7
IRF-7H
IRF7A
IRF7B
IRF7C
IRF7H
interferon regulatory factor 7 Genistein results in increased expression of IRF7 mRNA increases expression
mRNA 18847459
D019833 8660 IRS2
IRS-2
insulin receptor substrate 2 Genistein results in decreased expression of IRS2 mRNA decreases expression
mRNA 19371625
D019833 9636 ISG15
G1P2
IFI15
IP17
UCRP
hUCRP
ISG15 ubiquitin-like modifier ESR2 promotes the reaction [Genistein results in decreased expression of ISG15 protein] decreases expression
/ increases reaction
protein 20884965
D019833 9636 ISG15
G1P2
IFI15
IP17
UCRP
hUCRP
ISG15 ubiquitin-like modifier Genistein results in decreased expression of ISG15 protein decreases expression
protein 20884965
D019833 51477 ISYNA1
INO1
INOS
IPS
IPS_1
IPS-1
inositol-3-phosphate synthase 1 (EC:5.5.1.4) ESR2 promotes the reaction [Genistein results in decreased expression of ISYNA1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 51477 ISYNA1
INO1
INOS
IPS
IPS_1
IPS-1
inositol-3-phosphate synthase 1 (EC:5.5.1.4) ESR2 promotes the reaction [Genistein results in increased expression of ISYNA1 protein] increases expression
/ increases reaction
protein 20884965
D019833 51477 ISYNA1
INO1
INOS
IPS
IPS_1
IPS-1
inositol-3-phosphate synthase 1 (EC:5.5.1.4) Genistein results in decreased expression of ISYNA1 protein decreases expression
protein 20884965
D019833 51477 ISYNA1
INO1
INOS
IPS
IPS_1
IPS-1
inositol-3-phosphate synthase 1 (EC:5.5.1.4) Genistein results in increased expression of ISYNA1 protein increases expression
protein 20884965
D019833 3685 ITGAV
CD51
MSK8
VNRA
VTNR
integrin, alpha V ESR2 promotes the reaction [Genistein results in decreased expression of ITGAV protein] decreases expression
/ increases reaction
protein 20884965
D019833 3685 ITGAV
CD51
MSK8
VNRA
VTNR
integrin, alpha V Genistein results in decreased expression of ITGAV protein decreases expression
protein 20884965
D019833 3690 ITGB3
BDPLT16
BDPLT2
CD61
GP3A
GPIIIa
GT
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) Genistein results in decreased expression of ITGB3 mRNA decreases expression
mRNA 23019147
D019833 3694 ITGB6
integrin, beta 6 Genistein results in decreased expression of ITGB6 mRNA decreases expression
mRNA 23019147
D019833 3705 ITPK1
ITRPK1
inositol-tetrakisphosphate 1-kinase (EC:2.7.1.134 2.7.1.159) Genistein results in increased expression of ITPK1 mRNA increases expression
mRNA 16474171
D019833 3708 ITPR1
INSP3R1
IP3R
IP3R1
SCA15
SCA16
SCA29
inositol 1,4,5-trisphosphate receptor, type 1 Genistein results in increased expression of ITPR1 mRNA increases expression
mRNA 18444173
18847459
D019833 3725 JUN
AP-1
AP1
c-Jun
jun proto-oncogene Genistein results in increased activity of JUN protein increases activity
protein 17088408
D019833 3725 JUN
AP-1
AP1
c-Jun
jun proto-oncogene Genistein results in increased expression of JUN mRNA increases expression
mRNA 17266178
D019833 3727 JUND
AP-1
jun D proto-oncogene Genistein promotes the reaction [ESR1 protein binds to JUND promoter] affects binding
/ increases reaction
promoter 23019147
D019833 3728 JUP
ARVD12
CTNNG
DP3
DPIII
PDGB
PKGB
junction plakoglobin Genistein results in decreased expression of JUP mRNA decreases expression
mRNA 16474171
16705744
D019833 23254 KAZN
KAZ
kazrin, periplakin interacting protein Genistein results in increased expression of KAZN mRNA increases expression
mRNA 23019147
D019833 3754 KCNF1
IK8
KCNF
KV5.1
kH1
potassium voltage-gated channel, subfamily F, member 1 Genistein results in increased expression of KCNF1 mRNA increases expression
mRNA 19371625
23019147
D019833 26251 KCNG2
KCNF2
KV6.2
potassium voltage-gated channel, subfamily G, member 2 [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of KCNG2 mRNA affects cotreatment
/ increases expression
mRNA 16963248
D019833 3762 KCNJ5
CIR
GIRK4
KATP1
KIR3.4
LQT13
potassium inwardly-rectifying channel, subfamily J, member 5 Genistein results in increased expression of KCNJ5 mRNA increases expression
mRNA 19371625
23019147
D019833 60598 KCNK15
K2p15.1
KCNK11
KCNK14
KT3.3
TASK-5
TASK5
dJ781B1.1
potassium channel, subfamily K, member 15 Genistein results in increased expression of KCNK15 mRNA increases expression
mRNA 23019147
D019833 23510 KCTD2
potassium channel tetramerization domain containing 2 Genistein results in decreased expression of KCTD2 mRNA decreases expression
mRNA 16705744
D019833 222658 KCTD20
C6orf69
dJ108K11.3
potassium channel tetramerization domain containing 20 Genistein results in increased expression of KCTD20 mRNA increases expression
mRNA 19371625
D019833 10945 KDELR1
ERD2
ERD2.1
HDEL
PM23
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 Genistein results in decreased expression of KDELR1 mRNA decreases expression
mRNA 16705744
D019833 9768 NS5ATP9
OEATC
OEATC-1
OEATC1
PAF
PAF15
p15(PAF)
p15/PAF
p15PAF
KIAA0101 Genistein results in decreased expression of KIAA0101 mRNA decreases expression
mRNA 19371625
D019833 9768 NS5ATP9
OEATC
OEATC-1
OEATC1
PAF
PAF15
p15(PAF)
p15/PAF
p15PAF
KIAA0101 Genistein results in increased expression of KIAA0101 mRNA increases expression
mRNA 16474171
D019833 282442 Genistein results in decreased expression of KIAA0256 mRNA decreases expression
mRNA 16474171
D019833 9851 KIAA0753 ESR2 promotes the reaction [Genistein results in increased expression of KIAA0753 protein] increases expression
/ increases reaction
protein 20884965
D019833 9851 KIAA0753 Genistein results in increased expression of KIAA0753 protein increases expression
protein 20884965
D019833 23285 KIAA1107 ESR2 promotes the reaction [Genistein results in increased expression of KIAA1107 protein] increases expression
/ increases reaction
protein 20884965
D019833 23285 KIAA1107 Genistein results in increased expression of KIAA1107 protein increases expression
protein 20884965
D019833 57648 KIAA1522 Genistein results in decreased expression of KIAA1522 mRNA decreases expression
mRNA 16705744
D019833 3832 KIF11
EG5
HKSP
KNSL1
MCLMR
TRIP5
kinesin family member 11 Genistein results in increased expression of KIF11 mRNA increases expression
mRNA 16474171
D019833 9928 KIF14
kinesin family member 14 Genistein results in increased expression of KIF14 mRNA increases expression
mRNA 16474171
D019833 56992 KIF15
HKLP2
KNSL7
NY-BR-62
kinesin family member 15 Genistein results in increased expression of KIF15 mRNA increases expression
mRNA 16474171
D019833 10112 KIF20A
MKLP2
RAB6KIFL
kinesin family member 20A Genistein results in increased expression of KIF20A mRNA increases expression
mRNA 16474171
D019833 9493 KIF23
CHO1
KNSL5
MKLP-1
MKLP1
kinesin family member 23 Genistein results in increased expression of KIF23 mRNA increases expression
mRNA 16474171
D019833 11004 KIF2C
KNSL6
MCAK
kinesin family member 2C Genistein affects the expression of KIF2C mRNA affects expression
mRNA 18847459
D019833 24137 KIF4A
KIF4
KIF4G1
kinesin family member 4A Genistein results in increased expression of KIF4A mRNA increases expression
mRNA 16474171
D019833 9365 KL
klotho (EC:3.2.1.31) Genistein results in decreased expression of KL mRNA decreases expression
mRNA 20706672
D019833 54800 KLHL24
DRE1
KRIP6
kelch-like family member 24 Genistein results in increased expression of KLHL24 mRNA increases expression
mRNA 18847459
D019833 3817 KLK2
KLK2A2
hGK-1
hK2
kallikrein-related peptidase 2 (EC:3.4.21.35) Genistein results in decreased expression of KLK2 mRNA decreases expression
mRNA 15378649
D019833 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Genistein results in decreased expression of KLK3 mRNA decreases expression
mRNA 15378649
16865672
D019833 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Genistein results in increased expression of KLK3 mRNA increases expression
mRNA 12391264
D019833 4297 KMT2A
ALL-1
CXXC7
HRX
HTRX1
MLL
MLL/GAS7
MLL1A
TET1-MLL
TRX1
WDSTS
lysine (K)-specific methyltransferase 2A (EC:2.1.1.43) Genistein results in increased mutagenesis of KMT2A gene increases mutagenesis
gene 17468513
D019833 3838 KPNA2
IPOA1
QIP2
RCH1
SRP1alpha
karyopherin alpha 2 (RAG cohort 1, importin alpha 1) Genistein results in increased expression of KPNA2 mRNA increases expression
mRNA 16474171
D019833 448834 KPRP
C1orf45
keratinocyte proline-rich protein ESR1 promotes the reaction [Genistein results in decreased expression of KPRP protein] decreases expression
/ increases reaction
protein 20884965
D019833 448834 KPRP
C1orf45
keratinocyte proline-rich protein Genistein results in decreased expression of KPRP protein decreases expression
protein 20884965
D019833 3845 KRAS
C-K-RAS
CFC2
K-RAS2A
K-RAS2B
K-RAS4A
K-RAS4B
KI-RAS
KRAS1
KRAS2
NS
NS3
RASK2
Kirsten rat sarcoma viral oncogene homolog Genistein results in decreased expression of KRAS mRNA decreases expression
mRNA 15256057
16474171
D019833 3872 KRT17
K17
PC
PC2
PCHC1
keratin 17 Genistein results in decreased expression of KRT17 mRNA decreases expression
mRNA 19371625
D019833 3875 KRT18
CYK18
K18
keratin 18 ESR1 promotes the reaction [Genistein results in increased expression of KRT18 protein] increases expression
/ increases reaction
protein 20884965
D019833 3875 KRT18
CYK18
K18
keratin 18 ESR2 promotes the reaction [Genistein results in increased expression of KRT18 protein] increases expression
/ increases reaction
protein 20884965
D019833 3875 KRT18
CYK18
K18
keratin 18 Genistein results in increased expression of KRT18 protein increases expression
protein 20884965
D019833 3880 KRT19
CK19
K19
K1CS
keratin 19 ESR1 promotes the reaction [Genistein results in increased expression of KRT19 protein] increases expression
/ increases reaction
protein 20884965
D019833 3880 KRT19
CK19
K19
K1CS
keratin 19 ESR2 promotes the reaction [Genistein results in increased expression of KRT19 protein] increases expression
/ increases reaction
protein 20884965
D019833 3880 KRT19
CK19
K19
K1CS
keratin 19 Genistein results in increased expression of KRT19 protein increases expression
protein 20884965
D019833 25984 KRT23
CK23
HAIK1
K23
keratin 23 (histone deacetylase inducible) Genistein results in decreased expression of KRT23 mRNA decreases expression
mRNA 20884965
D019833 3885 KRT34
HA4
Ha-4
KRTHA4
hHa4
keratin 34 Genistein results in decreased expression of KRT34 mRNA decreases expression
mRNA 16705744
D019833 3852 KRT5
CK5
DDD
DDD1
EBS2
K5
KRT5A
keratin 5 Genistein results in decreased expression of KRT5 mRNA decreases expression
mRNA 20706672
D019833 3856 KRT8
CARD2
CK-8
CK8
CYK8
K2C8
K8
KO
keratin 8 ESR1 promotes the reaction [Genistein results in increased expression of KRT8 protein] increases expression
/ increases reaction
protein 20884965
D019833 3856 KRT8
CARD2
CK-8
CK8
CYK8
K2C8
K8
KO
keratin 8 ESR2 promotes the reaction [Genistein results in increased expression of KRT8 protein] increases expression
/ increases reaction
protein 20884965
D019833 3856 KRT8
CARD2
CK-8
CK8
CYK8
K2C8
K8
KO
keratin 8 Genistein results in decreased expression of KRT8 mRNA decreases expression
mRNA 16705744
D019833 3856 KRT8
CARD2
CK-8
CK8
CYK8
K2C8
K8
KO
keratin 8 Genistein results in increased expression of KRT8 protein increases expression
protein 20884965
D019833 90133 Genistein results in decreased expression of KRT8P12 mRNA decreases expression
mRNA 16705744
D019833 728279 KRTAP2-2
KAP2.2
keratin associated protein 2-2 Genistein results in decreased expression of KRTAP2-2 mRNA decreases expression
mRNA 23019147
D019833 85294 KRTAP2-4
KAP2.1B
KAP2.4
KRTAP2.4
keratin associated protein 2-4 Genistein results in decreased expression of KRTAP2-4 mRNA decreases expression
mRNA 23019147
D019833 3897 L1CAM
CAML1
CD171
HSAS
HSAS1
MASA
MIC5
N-CAM-L1
N-CAML1
NCAM-L1
S10
SPG1
L1 cell adhesion molecule Genistein results in decreased expression of L1CAM mRNA decreases expression
mRNA 16474171
D019833 3915 LAMC1
LAMB2
laminin, gamma 1 (formerly LAMB2) Genistein results in decreased expression of LAMC1 mRNA decreases expression
mRNA 16705744
D019833 3920 LAMP2
CD107b
LAMP-2
LAMPB
LGP110
lysosomal-associated membrane protein 2 ESR2 promotes the reaction [Genistein results in increased expression of LAMP2 protein] increases expression
/ increases reaction
protein 20884965
D019833 3920 LAMP2
CD107b
LAMP-2
LAMPB
LGP110
lysosomal-associated membrane protein 2 Genistein results in increased expression of LAMP2 protein increases expression
protein 20884965
D019833 3945 LDHB
LDH-B
LDH-H
LDHBD
TRG-5
lactate dehydrogenase B (EC:1.1.1.27) ESR2 promotes the reaction [Genistein results in decreased expression of LDHB protein] decreases expression
/ increases reaction
protein 20884965
D019833 3945 LDHB
LDH-B
LDH-H
LDHBD
TRG-5
lactate dehydrogenase B (EC:1.1.1.27) Genistein results in decreased expression of LDHB protein decreases expression
protein 20884965
D019833 7044 LEFTY2
EBAF
LEFTA
LEFTYA
TGFB4
left-right determination factor 2 Genistein results in decreased expression of LEFTY2 mRNA decreases expression
mRNA 19371625
D019833 93273 LEMD1
CT50
LEMP-1
LEM domain containing 1 Genistein results in increased expression of LEMD1 mRNA increases expression
mRNA 16705744
D019833 3952 LEP
LEPD
OB
OBS
leptin Genistein inhibits the reaction [LEP protein results in increased chemical synthesis of Reactive Oxygen Species] decreases reaction
/ increases chemical synthesis
protein 11342529
D019833 3952 LEP
LEPD
OB
OBS
leptin Genistein inhibits the reaction [LEP protein results in increased expression of CCL2] decreases reaction
/ increases expression
protein 11342529
D019833 3952 LEP
LEPD
OB
OBS
leptin Genistein results in decreased susceptibility to LEP protein decreases response to substance
protein 11342529
D019833 3955 LFNG
SCDO3
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (EC:2.4.1.222) Genistein results in increased expression of LFNG mRNA increases expression
mRNA 23019147
D019833 3956 LGALS1
GAL1
GBP
lectin, galactoside-binding, soluble, 1 Genistein results in decreased expression of LGALS1 mRNA decreases expression
mRNA 19371625
D019833 3963 LGALS7
GAL7
LGALS7A
lectin, galactoside-binding, soluble, 7 ESR1 promotes the reaction [Genistein results in decreased expression of LGALS7 protein] decreases expression
/ increases reaction
protein 20884965
D019833 3963 LGALS7
GAL7
LGALS7A
lectin, galactoside-binding, soluble, 7 Genistein results in decreased expression of LGALS7 protein decreases expression
protein 20884965
D019833 3980 LIG3
LIG2
ligase III, DNA, ATP-dependent (EC:6.5.1.1) Genistein results in decreased expression of LIG3 mRNA decreases expression
mRNA 15257099
D019833 4000 LMNA
CDCD1
CDDC
CMD1A
CMT2B1
EMD2
FPL
FPLD
FPLD2
HGPS
IDC
LDP1
LFP
LGMD1B
LMN1
LMNC
LMNL1
PRO1
lamin A/C ESR1 promotes the reaction [Genistein results in decreased expression of LMNA protein] decreases expression
/ increases reaction
protein 20884965
D019833 4000 LMNA
CDCD1
CDDC
CMD1A
CMT2B1
EMD2
FPL
FPLD
FPLD2
HGPS
IDC
LDP1
LFP
LGMD1B
LMN1
LMNC
LMNL1
PRO1
lamin A/C ESR2 promotes the reaction [Genistein results in decreased expression of LMNA protein] decreases expression
/ increases reaction
protein 20884965
D019833 4000 LMNA
CDCD1
CDDC
CMD1A
CMT2B1
EMD2
FPL
FPLD
FPLD2
HGPS
IDC
LDP1
LFP
LGMD1B
LMN1
LMNC
LMNL1
PRO1
lamin A/C ESR2 promotes the reaction [Genistein results in increased expression of LMNA protein] increases expression
/ increases reaction
protein 20884965
D019833 4000 LMNA
CDCD1
CDDC
CMD1A
CMT2B1
EMD2
FPL
FPLD
FPLD2
HGPS
IDC
LDP1
LFP
LGMD1B
LMN1
LMNC
LMNL1
PRO1
lamin A/C Genistein results in decreased expression of LMNA protein decreases expression
protein 20884965
D019833 4000 LMNA
CDCD1
CDDC
CMD1A
CMT2B1
EMD2
FPL
FPLD
FPLD2
HGPS
IDC
LDP1
LFP
LGMD1B
LMN1
LMNC
LMNL1
PRO1
lamin A/C Genistein results in increased expression of LMNA protein increases expression
protein 20884965
D019833 4001 LMNB1
ADLD
LMN
LMN2
LMNB
lamin B1 ESR1 promotes the reaction [Genistein results in decreased expression of LMNB1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 4001 LMNB1
ADLD
LMN
LMN2
LMNB
lamin B1 Genistein results in decreased expression of LMNB1 protein decreases expression
protein 20884965
D019833 84823 LMNB2
LAMB2
LMN2
lamin B2 ESR2 promotes the reaction [Genistein results in decreased expression of LMNB2 protein] decreases expression
/ increases reaction
protein 20884965
D019833 84823 LMNB2
LAMB2
LMN2
lamin B2 Genistein results in decreased expression of LMNB2 protein decreases expression
protein 20884965
D019833 9170 LPAR2
EDG-4
EDG4
LPA-2
LPA2
lysophosphatidic acid receptor 2 Genistein results in decreased expression of LPAR2 mRNA decreases expression
mRNA 16705744
D019833 4026 LPP
LIM domain containing preferred translocation partner in lipoma ESR1 promotes the reaction [Genistein results in decreased expression of LPP protein] decreases expression
/ increases reaction
protein 20884965
D019833 4026 LPP
LIM domain containing preferred translocation partner in lipoma Genistein results in decreased expression of LPP protein decreases expression
protein 20884965
D019833 64748 LPPR2
PRG4
lipid phosphate phosphatase-related protein type 2 (EC:3.1.3.4) Genistein results in increased expression of LPPR2 mRNA increases expression
mRNA 19371625
D019833 91355 LRP5L
low density lipoprotein receptor-related protein 5-like Genistein results in increased expression of LRP5L mRNA increases expression
mRNA 23019147
D019833 7804 LRP8
APOER2
HSZ75190
LRP-8
MCI1
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor Genistein results in increased expression of LRP8 mRNA increases expression
mRNA 23019147
D019833 131578 LRRC15
LIB
leucine rich repeat containing 15 Genistein results in increased expression of LRRC15 mRNA increases expression
mRNA 20884965
D019833 4057 LTF
GIG12
HLF2
LF
lactotransferrin [Genistein co-treated with ESR1 protein] results in increased expression of LTF mRNA affects cotreatment
/ increases expression
mRNA 21783566
D019833 4057 LTF
GIG12
HLF2
LF
lactotransferrin [Genistein co-treated with ESR2 protein] results in increased expression of LTF mRNA affects cotreatment
/ increases expression
mRNA 21783566
D019833 56925 LXN
ECI
TCI
latexin Genistein results in decreased expression of LXN mRNA decreases expression
mRNA 23019147
D019833 90624 LYRM7
C5orf31
MZM1L
LYR motif containing 7 ESR2 promotes the reaction [Genistein results in increased expression of LYRM7 protein] increases expression
/ increases reaction
protein 20884965
D019833 90624 LYRM7
C5orf31
MZM1L
LYR motif containing 7 Genistein results in increased expression of LYRM7 protein increases expression
protein 20884965
D019833 8379 MAD1L1
MAD1
PIG9
TP53I9
TXBP181
MAD1 mitotic arrest deficient-like 1 (yeast) Genistein results in increased expression of MAD1L1 mRNA increases expression
mRNA 16474171
D019833 8567 MADD
DENN
IG20
RAB3GEP
MAP-kinase activating death domain Genistein results in decreased expression of MADD mRNA decreases expression
mRNA 16705744
D019833 4094 MAF
CCA4
c-MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Genistein results in decreased expression of MAF mRNA decreases expression
mRNA 15378649
D019833 9935 MAFB
KRML
MCTO
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B Genistein results in increased expression of MAFB mRNA increases expression
mRNA 18847459
20884965
D019833 23764 MAFF
U-MAF
hMafF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F Genistein results in decreased expression of MAFF mRNA decreases expression
mRNA 20884965
D019833 28986 MAGEH1
APR-1
APR1
MAGEH
melanoma antigen family H, 1 Genistein results in increased expression of MAGEH1 mRNA increases expression
mRNA 20884965
D019833 4128 MAOA
MAO-A
monoamine oxidase A (EC:1.4.3.4) Genistein results in increased expression of MAOA mRNA increases expression
mRNA 11331657
D019833 5604 MAP2K1
CFC3
MAPKK1
MEK1
MKK1
PRKMK1
mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) Genistein results in increased phosphorylation of MAP2K1 protein increases phosphorylation
protein 19038232
D019833 5605 MAP2K2
CFC4
MAPKK2
MEK2
MKK2
PRKMK2
mitogen-activated protein kinase kinase 2 (EC:2.7.12.2) Genistein results in increased phosphorylation of MAP2K2 protein increases phosphorylation
protein 19038232
D019833 5606 MAP2K3
MAPKK3
MEK3
MKK3
PRKMK3
SAPKK-2
SAPKK2
mitogen-activated protein kinase kinase 3 (EC:2.7.12.2) Genistein results in decreased expression of MAP2K3 mRNA decreases expression
mRNA 16705744
D019833 4134 MAP4
microtubule-associated protein 4 ESR1 promotes the reaction [Genistein results in decreased expression of MAP4 protein] decreases expression
/ increases reaction
protein 20884965
D019833 4134 MAP4
microtubule-associated protein 4 ESR2 promotes the reaction [Genistein results in decreased expression of MAP4 protein] decreases expression
/ increases reaction
protein 20884965
D019833 4134 MAP4
microtubule-associated protein 4 Genistein results in decreased expression of MAP4 mRNA decreases expression
mRNA 16705744
D019833 4134 MAP4
microtubule-associated protein 4 Genistein results in decreased expression of MAP4 protein decreases expression
protein 20884965
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) [1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester co-treated with Genistein] inhibits the reaction [Thapsigargin promotes the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]] affects cotreatment
/ decreases reaction
/ increases phosphorylation
/ increases reaction
protein 16251475
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) AG 1879 inhibits the reaction [Genistein results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases phosphorylation
protein 16840783
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Genistein inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases phosphorylation
protein 16251475
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Genistein inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased phosphorylation of MAPK1 protein] affects localization
/ decreases reaction
/ increases phosphorylation
protein 10653605
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Genistein inhibits the reaction [Thapsigargin promotes the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]] decreases reaction
/ increases phosphorylation
/ increases reaction
protein 16251475
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Genistein results in increased activity of and results in increased phosphorylation of MAPK1 protein increases activity
/ increases phosphorylation
protein 19427779
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Genistein results in increased expression of and results in increased phosphorylation of MAPK1 protein increases expression
/ increases phosphorylation
protein 16149052
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Genistein results in increased phosphorylation of and results in increased activity of MAPK1 protein increases activity
/ increases phosphorylation
protein 15090535
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Genistein results in increased phosphorylation of MAPK1 protein increases phosphorylation
protein 16840783
17088408
19038232
19720055
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) [Tretinoin co-treated with Genistein] results in increased phosphorylation of MAPK1 protein affects cotreatment
/ increases phosphorylation
protein 16149052
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) U 0126 inhibits the reaction [Genistein results in increased activity of and results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 19427779
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) U 0126 inhibits the reaction [Genistein results in increased phosphorylation of MAPK1 protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) [U 0126 results in decreased phosphorylation of [MAPK1 protein co-treated with MAPK3 protein]] which results in decreased susceptibility to Genistein affects cotreatment
/ decreases phosphorylation
/ decreases response to substance
protein 19427779
D019833 5600 MAPK11
P38B
P38BETA2
PRKM11
SAPK2
SAPK2B
p38-2
p38Beta
mitogen-activated protein kinase 11 (EC:2.7.11.24) Genistein results in decreased phosphorylation of MAPK11 protein decreases phosphorylation
protein 19497411
D019833 5603 MAPK13
MAPK_13
MAPK-13
PRKM13
SAPK4
p38delta
mitogen-activated protein kinase 13 (EC:2.7.11.24) Genistein results in decreased expression of MAPK13 mRNA decreases expression
mRNA 19371625
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) [1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester co-treated with Genistein] inhibits the reaction [Thapsigargin promotes the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein]] affects cotreatment
/ decreases reaction
/ increases phosphorylation
/ increases reaction
protein 16251475
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) AG 1879 inhibits the reaction [Genistein results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases phosphorylation
protein 16840783
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Genistein inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases phosphorylation
protein 16251475
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Genistein inhibits the reaction [Thapsigargin promotes the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein]] decreases reaction
/ increases phosphorylation
/ increases reaction
protein 16251475
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Genistein results in increased activity of and results in increased phosphorylation of MAPK3 protein increases activity
/ increases phosphorylation
protein 19427779
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Genistein results in increased expression of and results in increased phosphorylation of MAPK3 protein increases expression
/ increases phosphorylation
protein 16149052
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Genistein results in increased phosphorylation of and results in increased activity of MAPK3 protein increases activity
/ increases phosphorylation
protein 15090535
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Genistein results in increased phosphorylation of MAPK3 protein increases phosphorylation
protein 16840783
17088408
19038232
19720055
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) MAPK3 gene mutant form inhibits the reaction [Genistein results in increased expression of FOS protein] decreases reaction
/ increases expression
gene 15090535
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) [Tretinoin co-treated with Genistein] results in increased phosphorylation of MAPK3 protein affects cotreatment
/ increases phosphorylation
protein 16149052
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) U 0126 inhibits the reaction [Genistein results in increased activity of and results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases activity
/ increases phosphorylation
protein 19427779
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) U 0126 inhibits the reaction [Genistein results in increased phosphorylation of MAPK3 protein] decreases reaction
/ increases phosphorylation
protein 19038232
D019833 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) [U 0126 results in decreased phosphorylation of [MAPK1 protein co-treated with MAPK3 protein]] which results in decreased susceptibility to Genistein affects cotreatment
/ decreases phosphorylation
/ decreases response to substance
protein 19427779
D019833 84930 MASTL
GREATWALL
GW
GWL
MAST-L
RP11-85G18.2
THC2
hGWL
microtubule associated serine/threonine kinase-like (EC:2.7.11.1) Genistein results in increased expression of MASTL mRNA increases expression
mRNA 16474171
D019833 4145 MATK
CHK
CTK
HHYLTK
HYL
HYLTK
Lsk
megakaryocyte-associated tyrosine kinase (EC:2.7.10.2) Genistein results in increased expression of MATK mRNA increases expression
mRNA 23019147
D019833 9782 MATR3
MPD2
VCPDM
matrin 3 ESR2 promotes the reaction [Genistein results in decreased expression of MATR3 protein] decreases expression
/ increases reaction
protein 20884965
D019833 9782 MATR3
MPD2
VCPDM
matrin 3 ESR2 promotes the reaction [Genistein results in increased expression of MATR3 protein] increases expression
/ increases reaction
protein 20884965
D019833 9782 MATR3
MPD2
VCPDM
matrin 3 Genistein results in decreased expression of MATR3 protein decreases expression
protein 20884965
D019833 9782 MATR3
MPD2
VCPDM
matrin 3 Genistein results in increased expression of MATR3 protein increases expression
protein 20884965
D019833 4150 MAZ
PUR1
Pur-1
SAF-1
SAF-2
SAF-3
ZF87
ZNF801
Zif87
MYC-associated zinc finger protein (purine-binding transcription factor) Genistein results in decreased expression of MAZ mRNA decreases expression
mRNA 16705744
D019833 8932 MBD2
DMTase
NY-CO-41
methyl-CpG binding domain protein 2 Genistein results in decreased activity of MBD2 protein decreases activity
protein 19221000
D019833 4157 MC1R
CMM5
MSH-R
SHEP2
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) Genistein results in decreased expression of MC1R mRNA decreases expression
mRNA 20706672
D019833 55388 MCM10
CNA43
DNA43
minichromosome maintenance complex component 10 Genistein results in increased expression of MCM10 mRNA increases expression
mRNA 16474171
D019833 4171 MCM2
BM28
CCNL1
CDCL1
D3S3194
MITOTIN
cdc19
minichromosome maintenance complex component 2 (EC:3.6.4.12) Genistein results in increased expression of MCM2 mRNA increases expression
mRNA 16474171
D019833 4175 MCM6
MCG40308
Mis5
P105MCM
minichromosome maintenance complex component 6 (EC:3.6.4.12) Genistein results in increased expression of MCM6 mRNA increases expression
mRNA 16474171
D019833 4176 MCM7
CDC47
MCM2
P1.1-MCM3
P1CDC47
P85MCM
PNAS146
minichromosome maintenance complex component 7 (EC:3.6.4.12) Genistein results in increased expression of MCM7 mRNA increases expression
mRNA 16474171
D019833 9656 MDC1
NFBD1
mediator of DNA-damage checkpoint 1 Genistein results in increased expression of MDC1 mRNA increases expression
mRNA 20884965
D019833 4192 MDK
ARAP
MK
NEGF2
midkine (neurite growth-promoting factor 2) Genistein results in decreased expression of MDK mRNA decreases expression
mRNA 19371625
D019833 4199 ME1
HUMNDME
MES
malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40) Genistein results in increased expression of ME1 mRNA increases expression
mRNA 16865672
D019833 4204 MECP2
AUTSX3
MRX16
MRX79
MRXS13
MRXSL
PPMX
RS
RTS
RTT
methyl CpG binding protein 2 (Rett syndrome) Genistein results in increased expression of MECP2 mRNA increases expression
mRNA 15256057
D019833 9282 MED14
CRSP150
CRSP2
CSRP
CXorf4
DRIP150
EXLM1
RGR1
TRAP170
mediator complex subunit 14 Genistein results in decreased expression of MED14 mRNA decreases expression
mRNA 16705744
D019833 9477 MED20
PRO0213
TRFP
mediator complex subunit 20 Genistein results in decreased expression of MED20 mRNA decreases expression
mRNA 16705744
D019833 9833 MELK
HPK38
maternal embryonic leucine zipper kinase (EC:2.7.11.1 2.7.10.2) Genistein results in increased expression of MELK mRNA increases expression
mRNA 16474171
D019833 4221 MEN1
MEAI
SCG2
multiple endocrine neoplasia I MEN1 protein inhibits the reaction [Genistein results in increased expression of FOS mRNA] decreases reaction
/ increases expression
protein 15090535
D019833 4222 MEOX1
KFS2
MOX1
mesenchyme homeobox 1 Genistein results in decreased expression of MEOX1 mRNA decreases expression
mRNA 19371625
D019833 4233 MET
AUTS9
HGFR
RCCP2
c-Met
met proto-oncogene (EC:2.7.10.1) Genistein results in increased expression of MET mRNA increases expression
mRNA 19371625
D019833 25840 METTL7A
AAM-B
methyltransferase like 7A ESR2 promotes the reaction [Genistein results in increased expression of METTL7A protein] increases expression
/ increases reaction
protein 20884965
D019833 25840 METTL7A
AAM-B
methyltransferase like 7A Genistein results in decreased expression of METTL7A mRNA decreases expression
mRNA 23019147
D019833 25840 METTL7A
AAM-B
methyltransferase like 7A Genistein results in increased expression of METTL7A protein increases expression
protein 20884965
D019833 4240 MFGE8
BA46
EDIL1
HMFG
HsT19888
MFG-E8
MFGM
OAcGD3S
SED1
SPAG10
hP47
milk fat globule-EGF factor 8 protein Genistein results in decreased expression of MFGE8 mRNA decreases expression
mRNA 19371625
D019833 9927 MFN2
CMT2A
CMT2A2
CPRP1
HSG
MARF
mitofusin 2 Genistein results in increased expression of MFN2 mRNA increases expression
mRNA 19371625
D019833 4242 MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (EC:2.4.1.222) Genistein results in increased expression of MFNG mRNA increases expression
mRNA 23019147
D019833 4255 MGMT
O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) Genistein results in increased expression of MGMT mRNA increases expression
mRNA 15703815
D019833 4256 MGP
MGLAP
NTI
matrix Gla protein ESR1 promotes the reaction [Genistein results in increased expression of MGP protein] increases expression
/ increases reaction
protein 20884965
D019833 4256 MGP
MGLAP
NTI
matrix Gla protein ESR2 promotes the reaction [Genistein results in increased expression of MGP protein] increases expression
/ increases reaction
protein 20884965
D019833 4256 MGP
MGLAP
NTI
matrix Gla protein Genistein results in increased expression of MGP protein increases expression
protein 20884965
D019833 574449 MIR492
MIRN492
hsa-mir-492
microRNA 492 Genistein results in decreased expression of MIR492 mRNA decreases expression
mRNA 23019147
D019833 724033 MIR663A
MIR663
MIRN663
hsa-mir-663
hsa-mir-663a
microRNA 663a Genistein results in increased expression of MIR663A mRNA increases expression
mRNA 23019147
D019833 4291 MLF1
myeloid leukemia factor 1 Genistein results in increased expression of MLF1 mRNA increases expression
mRNA 16474171
D019833 79682 CENPU
CENP50
CENPU50
KLIP1
MLF1IP
PBIP1
centromere protein U Genistein results in increased expression of MLF1IP mRNA increases expression
mRNA 16474171
D019833 197259 MLKL
mixed lineage kinase domain-like Genistein results in decreased expression of MLKL mRNA decreases expression
mRNA 18847459
D019833 4301 MLLT4
AF6
RP3-431P23.3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 Genistein results in decreased expression of MLLT4 mRNA decreases expression
mRNA 16705744
D019833 79083 MLPH
SLAC2-A
melanophilin Genistein results in increased expression of MLPH mRNA increases expression
mRNA 19371625
23019147
D019833 4312 MMP1
CLG
CLGN
matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) Genistein inhibits the reaction [Chromium results in increased expression of MMP1 mRNA] decreases reaction
/ increases expression
mRNA 15878362
D019833 4312 MMP1
CLG
CLGN
matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) Genistein inhibits the reaction [Cobalt results in increased expression of MMP1 mRNA] decreases reaction
/ increases expression
mRNA 15878362
D019833 4312 MMP1
CLG
CLGN
matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) Genistein inhibits the reaction [Phosphorylcholine analog results in increased expression of MMP1 mRNA] decreases reaction
/ increases expression
mRNA 15878362
D019833 4323 MMP14
MMP-14
MMP-X1
MT-MMP
MT-MMP_1
MT1-MMP
MT1MMP
MTMMP1
WNCHRS
matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80) Genistein results in decreased expression of MMP14 mRNA decreases expression
mRNA 15754008
D019833 4323 MMP14
MMP-14
MMP-X1
MT-MMP
MT-MMP_1
MT1-MMP
MT1MMP
MTMMP1
WNCHRS
matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80) Genistein results in decreased expression of MMP14 protein decreases expression
protein 16598420
D019833 4324 MMP15
MT2-MMP
MTMMP2
SMCP-2
matrix metallopeptidase 15 (membrane-inserted) (EC:3.4.24.-) Genistein results in decreased expression of MMP15 mRNA decreases expression
mRNA 15754008
D019833 4325 MMP16
C8orf57
MMP-X2
MT-MMP2
MT-MMP3
MT3-MMP
matrix metallopeptidase 16 (membrane-inserted) (EC:3.4.24.-) Genistein results in decreased expression of MMP16 mRNA decreases expression
mRNA 15754008
D019833 4326 MMP17
MT4-MMP
matrix metallopeptidase 17 (membrane-inserted) (EC:3.4.24.-) Genistein results in increased expression of MMP17 mRNA increases expression
mRNA 23019147
D019833 4313 MMP2
CLG4
CLG4A
MMP-II
MONA
TBE-1
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) Genistein results in decreased activity of MMP2 protein decreases activity
protein 16598420
D019833 4313 MMP2
CLG4
CLG4A
MMP-II
MONA
TBE-1
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) Genistein results in decreased expression of MMP2 mRNA decreases expression
mRNA 15754008
D019833 4318 MMP9
CLG4B
GELB
MANDP2
MMP-9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) Genistein results in decreased activity of MMP9 protein decreases activity
protein 16598420
D019833 4318 MMP9
CLG4B
GELB
MANDP2
MMP-9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) Genistein results in decreased expression of MMP9 mRNA decreases expression
mRNA 15256057
15754008
D019833 4318 MMP9
CLG4B
GELB
MANDP2
MMP-9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) Genistein results in decreased expression of MMP9 protein decreases expression
protein 15256057
D019833 4331 MNAT1
CAP35
MAT1
RNF66
TFB3
MNAT CDK-activating kinase assembly factor 1 Genistein results in increased expression of MNAT1 mRNA increases expression
mRNA 20884965
D019833 4335 MNT
MAD6
MXD6
ROX
bHLHd3
MAX network transcriptional repressor Genistein results in increased expression of MNT mRNA increases expression
mRNA 15256057
D019833 7841 MOGS
CDG2B
CWH41
DER7
GCS1
mannosyl-oligosaccharide glucosidase (EC:3.2.1.106) ESR1 promotes the reaction [Genistein results in decreased expression of MOGS protein] decreases expression
/ increases reaction
protein 20884965
D019833 7841 MOGS
CDG2B
CWH41
DER7
GCS1
mannosyl-oligosaccharide glucosidase (EC:3.2.1.106) Genistein results in decreased expression of MOGS protein decreases expression
protein 20884965
D019833 10198 MPHOSPH9
MPP-9
MPP9
M-phase phosphoprotein 9 Genistein results in increased expression of MPHOSPH9 mRNA increases expression
mRNA 16474171
16705744
D019833 84954 MPND
MPN domain containing Genistein results in increased expression of MPND mRNA increases expression
mRNA 18847459
D019833 55052 MRPL20
L20mt
MRP-L20
mitochondrial ribosomal protein L20 ESR1 promotes the reaction [Genistein results in increased expression of MRPL20 protein] increases expression
/ increases reaction
protein 20884965
D019833 55052 MRPL20
L20mt
MRP-L20
mitochondrial ribosomal protein L20 Genistein results in increased expression of MRPL20 protein increases expression
protein 20884965
D019833 740 MRPL49
C11orf4
L49mt
MRP-L49
NOF
NOF1
mitochondrial ribosomal protein L49 Genistein results in decreased expression of MRPL49 mRNA decreases expression
mRNA 16705744
D019833 124540 MSI2
MSI2H
musashi RNA-binding protein 2 Genistein results in decreased expression of MSI2 mRNA decreases expression
mRNA 18847459
D019833 4477 MSMB
HPC13
IGBF
MSP
MSPB
PN44
PRPS
PSP
PSP-94
PSP57
PSP94
microseminoprotein, beta- Genistein results in increased expression of MSMB mRNA increases expression
mRNA 19371625
D019833 4501 MT1X
MT-1l
MT1
metallothionein 1X Genistein results in increased expression of MT1X mRNA increases expression
mRNA 18847459
D019833 4502 MT2A
MT2
metallothionein 2A Genistein results in increased expression of MT2A mRNA increases expression
mRNA 10656621
D019833 4522 MTHFD1
MTHFC
MTHFD
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (EC:1.5.1.5 6.3.4.3 3.5.4.9) Genistein results in decreased expression of MTHFD1 mRNA decreases expression
mRNA 16705744
D019833 4582 MUC1
CA_15-3
CD227
EMA
H23AG
KL-6
MAM6
MCKD1
MUC-1
MUC-1/SEC
MUC-1/X
MUC1/ZD
PEM
PEMT
PUM
mucin 1, cell surface associated ESR2 promotes the reaction [Genistein results in increased expression of MUC1 protein] increases expression
/ increases reaction
protein 20884965
D019833 4582 MUC1
CA_15-3
CD227
EMA
H23AG
KL-6
MAM6
MCKD1
MUC-1
MUC-1/SEC
MUC-1/X
MUC1/ZD
PEM
PEMT
PUM
mucin 1, cell surface associated Genistein results in increased expression of MUC1 protein increases expression
protein 20884965
D019833 4597 MVD
FP17780
MPD
mevalonate (diphospho) decarboxylase (EC:4.1.1.33) Genistein results in decreased expression of MVD mRNA decreases expression
mRNA 16705744
D019833 4599 MX1
IFI-78K
IFI78
MX
MxA
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) ESR2 promotes the reaction [Genistein results in decreased expression of MX1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 4599 MX1
IFI-78K
IFI78
MX
MxA
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) Genistein results in decreased expression of MX1 protein decreases expression
protein 20884965
D019833 10608 MXD4
MAD4
MST149
MSTP149
bHLHc12
MAX dimerization protein 4 Genistein results in decreased expression of MXD4 mRNA decreases expression
mRNA 16474171
D019833 439921 MXRA7
PS1TP1
TMAP1
matrix-remodelling associated 7 Genistein results in increased expression of MXRA7 mRNA increases expression
mRNA 20884965
D019833 4602 MYB
Cmyb
c-myb
c-myb_CDS
efg
v-myb avian myeloblastosis viral oncogene homolog Genistein results in increased expression of MYB mRNA increases expression
mRNA 16474171
D019833 10514 MYBBP1A
P160
PAP2
MYB binding protein (P160) 1a Genistein results in increased expression of MYBBP1A mRNA increases expression
mRNA 23019147
D019833 4605 MYBL2
B-MYB
BMYB
v-myb avian myeloblastosis viral oncogene homolog-like 2 Genistein results in increased expression of MYBL2 mRNA increases expression
mRNA 16474171
D019833 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog [Genistein co-treated with arsenic trioxide] results in decreased expression of MYC protein affects cotreatment
/ decreases expression
protein 21078540
D019833 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog Genistein results in decreased expression of MYC protein decreases expression
protein 21078540
D019833 4609 MYC
MRTL
MYCC
bHLHe39
c-Myc
v-myc avian myelocytomatosis viral oncogene homolog Genistein results in increased expression of MYC mRNA increases expression
mRNA 16474171
17266178
23019147
D019833 4628 MYH10
NMMHC-IIB
NMMHCB
myosin, heavy chain 10, non-muscle ESR1 promotes the reaction [Genistein results in increased expression of MYH10 protein] increases expression
/ increases reaction
protein 20884965
D019833 4628 MYH10
NMMHC-IIB
NMMHCB
myosin, heavy chain 10, non-muscle Genistein results in increased expression of MYH10 protein increases expression
protein 20884965
D019833 79784 MYH14
DFNA4
DFNA4A
MHC16
MYH17
NMHC_II-C
NMHC-II-C
PNMHH
myosin
myosin, heavy chain 14, non-muscle (EC:3.6.4.1) ESR1 promotes the reaction [Genistein results in increased expression of MYH14 protein] increases expression
/ increases reaction
protein 20884965
D019833 79784 MYH14
DFNA4
DFNA4A
MHC16
MYH17
NMHC_II-C
NMHC-II-C
PNMHH
myosin
myosin, heavy chain 14, non-muscle (EC:3.6.4.1) Genistein results in increased expression of MYH14 protein increases expression
protein 20884965
D019833 4624 MYH6
ASD3
CMD1EE
CMH14
MYHC
MYHCA
SSS3
alpha-MHC
myosin, heavy chain 6, cardiac muscle, alpha Genistein results in decreased expression of MYH6 mRNA decreases expression
mRNA 16474171
D019833 4627 MYH9
BDPLT6
DFNA17
EPSTS
FTNS
MHA
NMHC-II-A
NMMHC-IIA
NMMHCA
myosin, heavy chain 9, non-muscle ESR1 promotes the reaction [Genistein results in increased expression of MYH9 protein] increases expression
/ increases reaction
protein 20884965
D019833 4627 MYH9
BDPLT6
DFNA17
EPSTS
FTNS
MHA
NMHC-II-A
NMMHC-IIA
NMMHCA
myosin, heavy chain 9, non-muscle Genistein results in increased expression of MYH9 protein increases expression
protein 20884965
D019833 103910 MYL12B
MLC-B
MRLC2
myosin, light chain 12B, regulatory ESR1 promotes the reaction [Genistein results in increased expression of MYL12B protein] increases expression
/ increases reaction
protein 20884965
D019833 103910 MYL12B
MLC-B
MRLC2
myosin, light chain 12B, regulatory Genistein results in increased expression of MYL12B protein increases expression
protein 20884965
D019833 4637 MYL6
ESMLC
LC17
LC17-GI
LC17-NM
LC17A
LC17B
MLC-3
MLC1SM
MLC3NM
MLC3SM
myosin, light chain 6, alkali, smooth muscle and non-muscle ESR1 promotes the reaction [Genistein results in increased expression of MYL6 protein] increases expression
/ increases reaction
protein 20884965
D019833 4637 MYL6
ESMLC
LC17
LC17-GI
LC17-NM
LC17A
LC17B
MLC-3
MLC1SM
MLC3NM
MLC3SM
myosin, light chain 6, alkali, smooth muscle and non-muscle Genistein results in increased expression of MYL6 protein increases expression
protein 20884965
D019833 29116 MYLIP
IDOL
MIR
myosin regulatory light chain interacting protein (EC:6.3.2.-) Genistein results in increased expression of MYLIP mRNA increases expression
mRNA 18847459
D019833 51168 MYO15A
DFNB3
MYO15
myosin XVA ESR1 promotes the reaction [Genistein results in decreased expression of MYO15A protein] decreases expression
/ increases reaction
protein 20884965
D019833 51168 MYO15A
DFNB3
MYO15
myosin XVA Genistein results in decreased expression of MYO15A protein decreases expression
protein 20884965
D019833 399687 MYO18A
MYSPDZ
SPR210
myosin XVIIIA Genistein results in increased expression of MYO18A mRNA increases expression
mRNA 23019147
D019833 27163 NAAA
ASAHL
PLT
N-acylethanolamine acid amidase (EC:3.5.1.-) Genistein results in increased expression of NAAA mRNA increases expression
mRNA 20884965
D019833 4665 NAB2
MADER
NGFI-A binding protein 2 (EGR1 binding protein 2) Genistein results in increased expression of NAB2 mRNA increases expression
mRNA 23019147
D019833 4676 NAP1L4
NAP1L4b
NAP2
NAP2L
hNAP2
nucleosome assembly protein 1-like 4 Genistein results in decreased expression of NAP1L4 mRNA decreases expression
mRNA 16705744
D019833 8775 NAPA
SNAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha Genistein results in decreased expression of NAPA mRNA decreases expression
mRNA 16705744
D019833 26502 NARF
IOP2
nuclear prelamin A recognition factor Genistein results in increased expression of NARF mRNA increases expression
mRNA 23019147
D019833 4678 NASP
FLB7527
PRO1999
nuclear autoantigenic sperm protein (histone-binding) ESR1 promotes the reaction [Genistein results in decreased expression of NASP protein] decreases expression
/ increases reaction
protein 20884965
D019833 4678 NASP
FLB7527
PRO1999
nuclear autoantigenic sperm protein (histone-binding) Genistein results in decreased expression of NASP protein decreases expression
protein 20884965
D019833 339983 NAT8L
CML3
NACED
NAT8-LIKE
N-acetyltransferase 8-like (GCN5-related, putative) (EC:2.3.1.17) Genistein results in increased expression of NAT8L mRNA increases expression
mRNA 23019147
D019833 4683 NBN
AT-V1
AT-V2
ATV
NBS
NBS1
P95
nibrin ESR1 promotes the reaction [Genistein results in increased expression of NBN protein] increases expression
/ increases reaction
protein 20884965
D019833 4683 NBN
AT-V1
AT-V2
ATV
NBS
NBS1
P95
nibrin Genistein results in increased expression of NBN protein increases expression
protein 20884965
D019833 9918 NCAPD2
CAP-D2
CNAP1
hCAP-D2
non-SMC condensin I complex, subunit D2 Genistein results in increased expression of NCAPD2 mRNA increases expression
mRNA 16474171
D019833 64151 NCAPG
CAPG
CHCG
NY-MEL-3
non-SMC condensin I complex, subunit G Genistein affects the expression of NCAPG mRNA affects expression
mRNA 18847459
D019833 64151 NCAPG
CAPG
CHCG
NY-MEL-3
non-SMC condensin I complex, subunit G Genistein results in increased expression of NCAPG mRNA increases expression
mRNA 16474171
D019833 400746 NCMAP
C1orf130
MP11
noncompact myelin associated protein Genistein results in increased expression of NCMAP mRNA increases expression
mRNA 19371625
D019833 8648 NCOA1
F-SRC-1
KAT13A
RIP160
SRC1
bHLHe42
bHLHe74
nuclear receptor coactivator 1 (EC:2.3.1.48) Genistein promotes the reaction [ESR1 protein binds to NCOA1 protein] affects binding
/ increases reaction
protein 10964929
D019833 8648 NCOA1
F-SRC-1
KAT13A
RIP160
SRC1
bHLHe42
bHLHe74
nuclear receptor coactivator 1 (EC:2.3.1.48) Genistein promotes the reaction [ESR2 protein binds to NCOA1 protein] affects binding
/ increases reaction
protein 10964929
D019833 10499 NCOA2
GRIP1
KAT13C
NCoA-2
SRC2
TIF2
bHLHe75
nuclear receptor coactivator 2 [Genistein binds to ESR1 protein] which binds to NCOA2 protein affects binding
protein 15123288
D019833 10499 NCOA2
GRIP1
KAT13C
NCoA-2
SRC2
TIF2
bHLHe75
nuclear receptor coactivator 2 [Genistein binds to ESR2 protein] which binds to NCOA2 protein affects binding
protein 15123288
D019833 10499 NCOA2
GRIP1
KAT13C
NCoA-2
SRC2
TIF2
bHLHe75
nuclear receptor coactivator 2 Genistein promotes the reaction [ESR1 protein binds to NCOA2 protein] affects binding
/ increases reaction
protein 10964929
D019833 10499 NCOA2
GRIP1
KAT13C
NCoA-2
SRC2
TIF2
bHLHe75
nuclear receptor coactivator 2 Genistein promotes the reaction [ESR2 protein binds to NCOA2 protein] affects binding
/ increases reaction
protein 10964929
D019833 10499 NCOA2
GRIP1
KAT13C
NCoA-2
SRC2
TIF2
bHLHe75
nuclear receptor coactivator 2 Genistein promotes the reaction [NCOA2 protein binds to ESR1 protein] affects binding
/ increases reaction
protein 15084758
D019833 8202 NCOA3
ACTR
AIB-1
AIB1
CAGH16
CTG26
KAT13B
RAC3
SRC-3
SRC3
TNRC14
TNRC16
TRAM-1
bHLHe42
pCIP
nuclear receptor coactivator 3 (EC:2.3.1.48) Genistein results in decreased expression of NCOA3 mRNA decreases expression
mRNA 16474171
D019833 8031 NCOA4
ARA70
ELE1
PTC3
RFG
nuclear receptor coactivator 4 Genistein results in increased expression of NCOA4 mRNA increases expression
mRNA 23019147
D019833 10403 NDC80
HEC
HEC1
HsHec1
KNTC2
TID3
hsNDC80
NDC80 kinetochore complex component Genistein results in increased expression of NDC80 mRNA increases expression
mRNA 16474171
D019833 4707 NDUFB1
CI-MNLL
CI-SGDH
MNLL
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa Genistein results in decreased expression of NDUFB1 mRNA decreases expression
mRNA 18847459
D019833 4739 NEDD9
CAS-L
CAS2
CASL
CASS2
HEF1
neural precursor cell expressed, developmentally down-regulated 9 Genistein results in decreased expression of NEDD9 mRNA decreases expression
mRNA 16474171
D019833 252969 NEIL2
NEH2
NEI2
nei endonuclease VIII-like 2 (E. coli) (EC:4.2.99.18) Genistein results in increased expression of NEIL2 mRNA increases expression
mRNA 19371625
D019833 4753 NELL2
NRP2
NEL-like 2 (chicken) Genistein results in decreased expression of NELL2 mRNA decreases expression
mRNA 15257099
D019833 10725 NFAT5
NF-AT5
NFATL1
NFATZ
OREBP
TONEBP
nuclear factor of activated T-cells 5, tonicity-responsive ESR1 promotes the reaction [Genistein results in increased expression of NFAT5 protein] increases expression
/ increases reaction
protein 20884965
D019833 10725 NFAT5
NF-AT5
NFATL1
NFATZ
OREBP
TONEBP
nuclear factor of activated T-cells 5, tonicity-responsive Genistein results in increased expression of NFAT5 protein increases expression
protein 20884965
D019833 4790 NFKB1
EBP-1
KBF1
NF-kB1
NF-kappa-B
NF-kappaB
NFKB-p105
NFKB-p50
NFkappaB
p105
p50
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 Genistein affects the localization of NFKB1 protein affects localization
protein 18431742
D019833 4791 NFKB2
H2TF1
LYT-10
LYT10
NF-kB2
p105
p52
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) ESR2 promotes the reaction [Genistein results in decreased expression of NFKB2 protein] decreases expression
/ increases reaction
protein 20884965
D019833 4791 NFKB2
H2TF1
LYT-10
LYT10
NF-kB2
p105
p52
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) Genistein results in decreased expression of NFKB2 protein decreases expression
protein 20884965
D019833 4792 NFKBIA
IKBA
MAD-3
NFKBI
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha Genistein affects the localization of NFKBIA protein affects localization
protein 18431742
D019833 4792 NFKBIA
IKBA
MAD-3
NFKBI
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha Genistein results in decreased expression of NFKBIA mRNA decreases expression
mRNA 20816778
D019833 9054 NFS1
IscS
NIFS
NFS1 cysteine desulfurase (EC:2.8.1.7) ESR1 promotes the reaction [Genistein results in decreased expression of NFS1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 9054 NFS1
IscS
NIFS
NFS1 cysteine desulfurase (EC:2.8.1.7) Genistein results in decreased expression of NFS1 protein decreases expression
protein 20884965
D019833 374354 NHLRC2
NHL repeat containing 2 Genistein results in decreased expression of NHLRC2 mRNA decreases expression
mRNA 18847459
D019833 4814 NINJ1
NIN1
NINJURIN
ninjurin 1 Genistein results in increased expression of NINJ1 mRNA increases expression
mRNA 18847459
D019833 348938 NIPAL4
ARCI6
ICHTHYIN
ICHYN
NIPA-like domain containing 4 Genistein results in decreased expression of NIPAL4 mRNA decreases expression
mRNA 16705744
D019833 25836 NIPBL
CDLS
CDLS1
IDN3
IDN3-B
Scc2
Nipped-B homolog (Drosophila) Genistein results in increased expression of NIPBL mRNA increases expression
mRNA 19371625
D019833 4824 NKX3-1
BAPX2
NKX3
NKX3.1
NKX3A
NK3 homeobox 1 Genistein results in decreased expression of NKX3-1 mRNA decreases expression
mRNA 15378649
16865672
D019833 57486 NLN
AGTBP
EP24.16
MEP
MOP
neurolysin (metallopeptidase M3 family) (EC:3.4.24.16) ESR1 promotes the reaction [Genistein results in decreased expression of NLN protein] decreases expression
/ increases reaction
protein 20884965
D019833 57486 NLN
AGTBP
EP24.16
MEP
MOP
neurolysin (metallopeptidase M3 family) (EC:3.4.24.16) Genistein results in decreased expression of NLN protein decreases expression
protein 20884965
D019833 4836 NMT1
NMT
N-myristoyltransferase 1 (EC:2.3.1.97) Genistein results in decreased expression of NMT1 mRNA decreases expression
mRNA 16705744
D019833 65083 NOL6
NRAP
UTP22
bA311H10.1
nucleolar protein 6 (RNA-associated) Genistein results in increased expression of NOL6 mRNA increases expression
mRNA 23019147
D019833 4839 NOP2
NOL1
NOP120
NSUN1
p120
NOP2 nucleolar protein Genistein results in increased expression of NOP2 mRNA increases expression
mRNA 23019147
D019833 4843 NOS2
HEP-NOS
INOS
NOS
NOS2A
nitric oxide synthase 2, inducible (EC:1.14.13.39) Genistein results in decreased expression of NOS2 mRNA decreases expression
mRNA 20706672
D019833 404036 Genistein results in decreased expression of NOS2A mRNA decreases expression
mRNA 20816778
D019833 4846 NOS3
ECNOS
eNOS
nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) Genistein inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS3 mRNA] decreases reaction
/ increases expression
mRNA 20021702
D019833 4846 NOS3
ECNOS
eNOS
nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) Genistein results in decreased expression of NOS3 mRNA decreases expression
mRNA 20021702
D019833 4846 NOS3
ECNOS
eNOS
nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) Genistein results in increased activity of NOS3 protein increases activity
protein 16840783
D019833 4846 NOS3
ECNOS
eNOS
nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) Genistein results in increased expression of NOS3 mRNA increases expression
mRNA 20706672
D019833 10577 NPC2
EDDM1
HE1
Niemann-Pick disease, type C2 ESR1 promotes the reaction [Genistein results in decreased expression of NPC2 protein] decreases expression
/ increases reaction
protein 20884965
D019833 10577 NPC2
EDDM1
HE1
Niemann-Pick disease, type C2 Genistein results in decreased expression of NPC2 protein decreases expression
protein 20884965
D019833 9284 NPIPA1
NPIP
morpheus
nuclear pore complex interacting protein family, member A1 Genistein results in decreased expression of NPIPA1 mRNA decreases expression
mRNA 16705744
D019833 23117 NPIPB3
KIAA0220L
NPIPB5
NPIPL3
nuclear pore complex interacting protein family, member B3 Genistein results in increased expression of NPIPB3 mRNA increases expression
mRNA 23019147
D019833 4869 NPM1
B23
NPM
nucleophosmin (nucleolar phosphoprotein B23, numatrin) ESR1 promotes the reaction [Genistein results in increased expression of NPM1 protein] increases expression
/ increases reaction
protein 20884965
D019833 4869 NPM1
B23
NPM
nucleophosmin (nucleolar phosphoprotein B23, numatrin) ESR2 promotes the reaction [Genistein results in increased expression of NPM1 protein] increases expression
/ increases reaction
protein 20884965
D019833 4869 NPM1
B23
NPM
nucleophosmin (nucleolar phosphoprotein B23, numatrin) Genistein results in increased expression of NPM1 protein increases expression
protein 20884965
D019833 4880 NPPC
CNP
CNP2
natriuretic peptide C Genistein results in increased expression of NPPC mRNA increases expression
mRNA 23019147
D019833 4881 NPR1
ANPRA
ANPa
GUC2A
GUCY2A
NPRA
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) (EC:4.6.1.2) Genistein results in increased expression of NPR1 mRNA increases expression
mRNA 16399490
D019833 283869 NPW
L8
L8C
PPL8
PPNPW
neuropeptide W Genistein results in increased expression of NPW mRNA increases expression
mRNA 20884965
D019833 1728 NQO1
DHQU
DIA4
DTD
NMOR1
NMORI
QR1
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) Genistein results in decreased expression of NQO1 mRNA decreases expression
mRNA 18497090
D019833 1728 NQO1
DHQU
DIA4
DTD
NMOR1
NMORI
QR1
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) Genistein results in increased expression of NQO1 mRNA increases expression
mRNA 18847459
D019833 8856 NR1I2
BXR
ONR1
PAR
PAR1
PAR2
PARq
PRR
PXR
SAR
SXR
nuclear receptor subfamily 1, group I, member 2 Genistein binds to and results in increased activity of NR1I2 protein affects binding
/ increases activity
protein 16054614
D019833 7182 NR2C2
TAK1
TR2R1
TR4
hTAK1
nuclear receptor subfamily 2, group C, member 2 Genistein results in decreased expression of NR2C2 mRNA decreases expression
mRNA 16705744
D019833 3164 NR4A1
GFRP1
HMR
N10
NAK-1
NGFIB
NP10
NUR77
TR3
nuclear receptor subfamily 4, group A, member 1 Genistein results in decreased expression of NR4A1 mRNA decreases expression
mRNA 16705744
D019833 3164 NR4A1
GFRP1
HMR
N10
NAK-1
NGFIB
NP10
NUR77
TR3
nuclear receptor subfamily 4, group A, member 1 Genistein results in increased expression of NR4A1 mRNA increases expression
mRNA 23019147
D019833 441478 NRARP
NOTCH-regulated ankyrin repeat protein Genistein results in decreased expression of NRARP mRNA decreases expression
mRNA 23019147
D019833 29959 NRBP1
BCON3
MADM
MUDPNP
NRBP
nuclear receptor binding protein 1 Genistein results in decreased expression of NRBP1 mRNA decreases expression
mRNA 16705744
D019833 8204 NRIP1
RIP140
nuclear receptor interacting protein 1 Genistein results in increased expression of NRIP1 mRNA increases expression
mRNA 15757668
19371625
23019147
D019833 56675 NRIP3
C11orf14
NY-SAR-105
nuclear receptor interacting protein 3 Genistein results in increased expression of NRIP3 mRNA increases expression
mRNA 20884965
D019833 8829 NRP1
BDCA4
CD304
NP1
NRP
VEGF165R
neuropilin 1 Genistein affects the expression of NRP1 mRNA affects expression
mRNA 16399490
D019833 8828 NRP2
NP2
NPN2
PRO2714
VEGF165R2
neuropilin 2 Genistein affects the expression of NRP2 mRNA affects expression
mRNA 16399490
D019833 4902 NRTN
NTN
neurturin Genistein results in increased expression of NRTN mRNA increases expression
mRNA 19371625
23019147
D019833 4926 NUMA1
NUMA
nuclear mitotic apparatus protein 1 ESR2 promotes the reaction [Genistein results in increased expression of NUMA1 protein] increases expression
/ increases reaction
protein 20884965
D019833 4926 NUMA1
NUMA
nuclear mitotic apparatus protein 1 Genistein results in increased expression of NUMA1 protein increases expression
protein 20884965
D019833 158046 NXNL2
C9orf121
RDCVF2
nucleoredoxin-like 2 (EC:1.8.1.8) Genistein results in increased expression of NXNL2 mRNA increases expression
mRNA 23019147
D019833 100506658 OCLN
BLCPMG
occludin (EC:2.1.1.67) Genistein results in decreased expression of OCLN mRNA decreases expression
mRNA 20816778
D019833 11054 OGFR
opioid growth factor receptor Genistein results in increased expression of OGFR mRNA increases expression
mRNA 23019147
D019833 10439 OLFM1
AMY
NOE1
NOELIN1
OlfA
olfactomedin 1 Genistein results in increased expression of OLFM1 mRNA increases expression
mRNA 16474171
19371625
D019833 56944 OLFML3
HNOEL-iso
OLF44
olfactomedin-like 3 [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of OLFML3 mRNA affects cotreatment
/ increases expression
mRNA 16963248
D019833 56944 OLFML3
HNOEL-iso
OLF44
olfactomedin-like 3 Genistein results in increased expression of OLFML3 mRNA increases expression
mRNA 16474171
19371625
23019147
D019833 29948 OSGIN1
BDGI
OKL38
oxidative stress induced growth inhibitor 1 Genistein results in increased expression of OSGIN1 mRNA increases expression
mRNA 18847459
D019833 78990 OTUB2
C14orf137
OTB2
OTU2
OTU domain, ubiquitin aldehyde binding 2 (EC:3.4.19.12) Genistein results in increased expression of OTUB2 mRNA increases expression
mRNA 20884965
D019833 5032 P2RY11
P2Y11
purinergic receptor P2Y, G-protein coupled, 11 Genistein results in increased expression of P2RY11 mRNA increases expression
mRNA 23019147
D019833 5036 PA2G4
EBP1
HG4-1
p38-2G4
proliferation-associated 2G4, 38kDa Genistein results in decreased expression of PA2G4 mRNA decreases expression
mRNA 16705744
D019833 5064 PALM
paralemmin Genistein results in increased expression of PALM mRNA increases expression
mRNA 23019147
D019833 142 PARP1
ADPRT
ADPRT_1
ADPRT1
ARTD1
PARP
PARP-1
PPOL
pADPRT-1
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) [Fluorouracil co-treated with Genistein] results in increased cleavage of PARP1 protein affects cotreatment
/ increases cleavage
protein 15896711
D019833 142 PARP1
ADPRT
ADPRT_1
ADPRT1
ARTD1
PARP
PARP-1
PPOL
pADPRT-1
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) [Genistein co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein affects cotreatment
/ increases cleavage
protein 21078540
D019833 142 PARP1
ADPRT
ADPRT_1
ADPRT1
ARTD1
PARP
PARP-1
PPOL
pADPRT-1
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) Genistein results in increased cleavage of PARP1 protein increases cleavage
protein 12791511
21078540
D019833 55872 PBK
CT84
Nori-3
SPK
TOPK
PDZ binding kinase (EC:2.7.12.2) Genistein affects the expression of PBK mRNA affects expression
mRNA 18847459
D019833 55872 PBK
CT84
Nori-3
SPK
TOPK
PDZ binding kinase (EC:2.7.12.2) Genistein results in increased expression of PBK mRNA increases expression
mRNA 16474171
D019833 56133 PCDHB2
PCDH-BETA2
protocadherin beta 2 Genistein results in increased expression of PCDHB2 mRNA increases expression
mRNA 20884965
D019833 56130 PCDHB6
PCDH-BETA6
protocadherin beta 6 Genistein results in increased expression of PCDHB6 mRNA increases expression
mRNA 20884965
D019833 5106 PCK2
PEPCK
PEPCK-M
PEPCK2
phosphoenolpyruvate carboxykinase 2 (mitochondrial) (EC:4.1.1.32) Genistein results in increased expression of PCK2 mRNA increases expression
mRNA 15757668
D019833 5111 PCNA
proliferating cell nuclear antigen Genistein results in decreased expression of PCNA decreases expression
21161820
D019833 5111 PCNA
proliferating cell nuclear antigen Genistein results in decreased expression of PCNA protein decreases expression
protein 16149052
D019833 5111 PCNA
proliferating cell nuclear antigen Genistein results in increased expression of PCNA mRNA increases expression
mRNA 16474171
D019833 5121 PCP4
PEP-19
Purkinje cell protein 4 Genistein results in increased expression of PCP4 mRNA increases expression
mRNA 16474171
D019833 22984 PDCD11
ALG-4
ALG4
NFBP
RRP5
programmed cell death 11 Genistein results in increased expression of PDCD11 mRNA increases expression
mRNA 23019147
D019833 27250 PDCD4
H731
programmed cell death 4 (neoplastic transformation inhibitor) Genistein results in increased expression of PDCD4 mRNA increases expression
mRNA 15256057
D019833 10015 PDCD6IP
AIP1
ALIX
DRIP4
HP95
programmed cell death 6 interacting protein Genistein results in increased expression of PDCD6IP mRNA increases expression
mRNA 18847459
D019833 10081 PDCD7
ES18
HES18
programmed cell death 7 Genistein results in increased expression of PDCD7 mRNA increases expression
mRNA 19371625
D019833 100135774 Genistein inhibits the reaction [Chondroitin Sulfates promotes the reaction [PDGF protein results in increased phosphorylation of and results in increased activity of PDGFRB protein]] decreases reaction
/ increases activity
/ increases phosphorylation
/ increases reaction
protein 16945567
D019833 5159 PDGFRB
CD140B
IBGC4
IMF1
JTK12
PDGFR
PDGFR-1
PDGFR1
platelet-derived growth factor receptor, beta polypeptide (EC:2.7.10.1) Genistein inhibits the reaction [Chondroitin Sulfates promotes the reaction [PDGF protein results in increased phosphorylation of and results in increased activity of PDGFRB protein]] decreases reaction
/ increases activity
/ increases phosphorylation
/ increases reaction
protein 16945567
D019833 10954 PDIA5
PDIR
protein disulfide isomerase family A, member 5 (EC:5.3.4.1) Genistein results in increased expression of PDIA5 mRNA increases expression
mRNA 20884965
D019833 5163 PDK1
pyruvate dehydrogenase kinase, isozyme 1 (EC:2.7.11.2) Genistein results in decreased phosphorylation of PDK1 protein decreases phosphorylation
protein 18431742
D019833 64236 PDLIM2
MYSTIQUE
SLIM
PDZ and LIM domain 2 (mystique) [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of PDLIM2 mRNA affects cotreatment
/ increases expression
mRNA 16963248
D019833 5174 PDZK1
CAP70
CLAMP
NHERF-3
NHERF3
PDZD1
PDZ domain containing 1 Genistein results in increased expression of PDZK1 mRNA increases expression
mRNA 15757668
D019833 23089 PEG10
EDR
HB-1
MEF3L
Mar2
Mart2
RGAG3
paternally expressed 10 Genistein results in increased expression of PEG10 mRNA increases expression
mRNA 23019147
D019833 192111 PGAM5
BXLBV68
phosphoglycerate mutase family member 5 (EC:3.1.3.16) Genistein results in increased expression of PGAM5 mRNA increases expression
mRNA 23019147
D019833 54858 PGPEP1
PGP
PGP-I
PGPI
Pcp
pyroglutamyl-peptidase I (EC:3.4.19.3) Genistein results in increased expression of PGPEP1 mRNA increases expression
mRNA 23019147
D019833 5241 PGR
NR3C3
PR
progesterone receptor ESR1 protein inhibits the reaction [Genistein results in increased expression of PGR mRNA] decreases reaction
/ increases expression
mRNA 23384675
D019833 5241 PGR
NR3C3
PR
progesterone receptor Genistein results in decreased expression of PGR mRNA decreases expression
mRNA 20706672
D019833 5241 PGR
NR3C3
PR
progesterone receptor Genistein results in increased expression of PGR mRNA increases expression
mRNA 11368622
16076101
19371625
20884965
23384675
23524099
D019833 9678 PHF14
PHD finger protein 14 Genistein results in decreased expression of PHF14 mRNA decreases expression
mRNA 15256057
D019833 7262 PHLDA2
BRW1C
BWR1C
HLDA2
IPL
TSSC3
pleckstrin homology-like domain, family A, member 2 Genistein results in increased expression of PHLDA2 mRNA increases expression
mRNA 15256057
23019147
D019833 5296 PIK3R2
MPPH
P85B
p85
p85-BETA
phosphoinositide-3-kinase, regulatory subunit 2 (beta) Genistein results in decreased expression of PIK3R2 mRNA decreases expression
mRNA 16705744
D019833 8503 PIK3R3
p55
p55-GAMMA
phosphoinositide-3-kinase, regulatory subunit 3 (gamma) Genistein results in increased expression of PIK3R3 mRNA increases expression
mRNA 15378649
D019833 29990 PILRB
FDFACT1
FDFACT2
paired immunoglobin-like type 2 receptor beta Genistein results in decreased expression of PILRB mRNA decreases expression
mRNA 16705744
D019833 5292 PIM1
PIM
pim-1 oncogene (EC:2.7.11.1) Genistein results in increased expression of PIM1 mRNA increases expression
mRNA 19371625
23019147
D019833 5304 PIP
GCDFP-15
GCDFP15
GPIP4
prolactin-induced protein ESR1 promotes the reaction [Genistein results in decreased expression of PIP protein] decreases expression
/ increases reaction
protein 20884965
D019833 5304 PIP
GCDFP-15
GCDFP15
GPIP4
prolactin-induced protein ESR2 promotes the reaction [Genistein results in increased expression of PIP protein] increases expression
/ increases reaction
protein 20884965
D019833 5304 PIP
GCDFP-15
GCDFP15
GPIP4
prolactin-induced protein Genistein results in decreased expression of PIP protein decreases expression
protein 20884965
D019833 5304 PIP
GCDFP-15
GCDFP15
GPIP4
prolactin-induced protein Genistein results in increased expression of PIP protein increases expression
protein 20884965
D019833 51268 PIPOX
LPIPOX
pipecolic acid oxidase (EC:1.5.3.1 1.5.3.7) Genistein results in increased expression of PIPOX mRNA increases expression
mRNA 23019147
D019833 26207 PITPNC1
M-RDGB-beta
MRDGBbeta
RDGB-BETA
RDGBB
RDGBB1
phosphatidylinositol transfer protein, cytoplasmic 1 Genistein results in increased expression of PITPNC1 mRNA increases expression
mRNA 20884965
D019833 5320 PLA2G2A
MOM1
PLA2
PLA2B
PLA2L
PLA2S
PLAS1
sPLA2
phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4) Genistein results in decreased expression of PLA2G2A mRNA decreases expression
mRNA 20816778
D019833 5327 PLAT
T-PA
TPA
plasminogen activator, tissue (EC:3.4.21.68) Genistein results in increased expression of PLAT mRNA increases expression
mRNA 23019147
D019833 5328 PLAU
ATF
BDPLT5
QPD
UPA
URK
u-PA
plasminogen activator, urokinase (EC:3.4.21.73) Genistein results in decreased expression of PLAU mRNA decreases expression
mRNA 23019147
D019833 5328 PLAU
ATF
BDPLT5
QPD
UPA
URK
u-PA
plasminogen activator, urokinase (EC:3.4.21.73) Genistein results in increased expression of PLAU mRNA increases expression
mRNA 18025290
D019833 23236 PLCB1
EIEE12
PI-PLC
PLC-154
PLC-I
PLC154
PLCB1A
PLCB1B
phospholipase C, beta 1 (phosphoinositide-specific) (EC:3.1.4.11) Genistein results in increased expression of PLCB1 mRNA increases expression
mRNA 19371625
23019147
D019833 5339 PLEC
EBS1
EBSO
HD1
LGMD2Q
PCN
PLEC1
PLEC1b
PLTN
plectin Genistein results in decreased expression of PLEC mRNA decreases expression
mRNA 16705744
D019833 10769 PLK2
SNK
hPlk2
hSNK
polo-like kinase 2 (EC:2.7.11.21) Genistein results in decreased expression of PLK2 mRNA decreases expression
mRNA 23019147
D019833 10733 PLK4
SAK
STK18
polo-like kinase 4 (EC:2.7.11.21) Genistein results in increased expression of PLK4 mRNA increases expression
mRNA 16474171
D019833 5351 PLOD1
EDS6
LH
LH1
LLH
PLOD
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (EC:1.14.11.4) Genistein results in increased expression of PLOD1 mRNA increases expression
mRNA 16474171
D019833 8985 PLOD3
LH3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (EC:1.14.11.4) Genistein results in increased expression of PLOD3 mRNA increases expression
mRNA 20706672
D019833 5354 PLP1
GPM6C
HLD1
MMPL
PLP
PLP/DM20
PMD
SPG2
proteolipid protein 1 Genistein results in decreased expression of PLP1 mRNA decreases expression
mRNA 18444173
D019833 5364 PLXNB1
PLEXIN-B1
PLXN5
SEP
plexin B1 Genistein results in decreased expression of PLXNB1 mRNA decreases expression
mRNA 16705744
D019833 56937 PMEPA1
STAG1
TMEPAI
prostate transmembrane protein, androgen induced 1 Genistein results in decreased expression of PMEPA1 mRNA decreases expression
mRNA 15378649
16474171
D019833 25953 PNKD
BRP17
DYT8
FPD1
KIPP1184
MR-1
MR1
PDC
PKND1
TAHCCP2
paroxysmal nonkinesigenic dyskinesia (EC:3.1.2.6) ESR1 promotes the reaction [Genistein results in decreased expression of PNKD protein] decreases expression
/ increases reaction
protein 20884965
D019833 25953 PNKD
BRP17
DYT8
FPD1
KIPP1184
MR-1
MR1
PDC
PKND1
TAHCCP2
paroxysmal nonkinesigenic dyskinesia (EC:3.1.2.6) Genistein results in decreased expression of PNKD protein decreases expression
protein 20884965
D019833 5411 PNN
DRS
DRSP
SDK3
memA
pinin, desmosome associated protein [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of PNN mRNA affects cotreatment
/ increases expression
mRNA 16963248
D019833 10957 PNRC1
B4-2
PNAS-145
PROL2
PRR2
proline-rich nuclear receptor coactivator 1 Genistein promotes the reaction [ESRRB protein binds to PNRC1 protein] affects binding
/ increases reaction
protein 14638870
D019833 10957 PNRC1
B4-2
PNAS-145
PROL2
PRR2
proline-rich nuclear receptor coactivator 1 Genistein promotes the reaction [ESRRG protein binds to PNRC1 protein] affects binding
/ increases reaction
protein 14638870
D019833 10957 PNRC1
B4-2
PNAS-145
PROL2
PRR2
proline-rich nuclear receptor coactivator 1 Genistein results in decreased expression of PNRC1 mRNA decreases expression
mRNA 23019147
D019833 23509 POFUT1
DDD2
FUT12
O-FUT
O-Fuc-T
O-FucT-1
OFUCT1
protein O-fucosyltransferase 1 (EC:2.4.1.221) ESR1 promotes the reaction [Genistein results in decreased expression of POFUT1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 23509 POFUT1
DDD2
FUT12
O-FUT
O-Fuc-T
O-FucT-1
OFUCT1
protein O-fucosyltransferase 1 (EC:2.4.1.221) Genistein results in decreased expression of POFUT1 protein decreases expression
protein 20884965
D019833 57804 POLD4
POLDS
p12
polymerase (DNA-directed), delta 4, accessory subunit Genistein results in decreased expression of POLD4 mRNA decreases expression
mRNA 16474171
D019833 5432 POLR2C
RPB3
RPB31
hRPB33
hsRPB3
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa (EC:2.7.7.6) Genistein results in increased expression of POLR2C mRNA increases expression
mRNA 19371625
D019833 5442 POLRMT
APOLMT
MTRNAP
MTRPOL
h-mtRPOL
polymerase (RNA) mitochondrial (DNA directed) (EC:2.7.7.6) Genistein results in increased expression of POLRMT mRNA increases expression
mRNA 23019147
D019833 5443 POMC
ACTH
CLIP
LPH
MSH
NPP
POC
proopiomelanocortin Genistein results in decreased expression of POMC mRNA decreases expression
mRNA 20706672
D019833 5458 POU4F2
BRN3.2
BRN3B
Brn-3b
POU class 4 homeobox 2 [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of POU4F2 mRNA affects cotreatment
/ decreases expression
mRNA 16963248
D019833 56342 PPAN
BXDC3
SSF
SSF-1
SSF1
SSF2
peter pan homolog (Drosophila) Genistein results in increased expression of PPAN mRNA increases expression
mRNA 23019147
D019833 8613 PPAP2B
Dri42
LPP3
PAP2B
VCIP
phosphatidic acid phosphatase type 2B (EC:3.1.3.4) Genistein results in decreased expression of PPAP2B mRNA decreases expression
mRNA 16474171
D019833 8613 PPAP2B
Dri42
LPP3
PAP2B
VCIP
phosphatidic acid phosphatase type 2B (EC:3.1.3.4) Genistein results in increased expression of PPAP2B mRNA increases expression
mRNA 23019147
D019833 8612 PPAP2C
LPP2
PAP-2c
PAP2-g
phosphatidic acid phosphatase type 2C (EC:3.1.3.4) Genistein results in decreased expression of PPAP2C mRNA decreases expression
mRNA 16474171
D019833 5468 PPARG
CIMT1
GLM1
NR1C3
PPARG1
PPARG2
PPARgamma
peroxisome proliferator-activated receptor gamma Genistein results in decreased expression of PPARG mRNA decreases expression
mRNA 20706672
D019833 133522 PPARGC1B
ERRL1
PERC
PGC-1(beta)
PGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta Genistein results in increased expression of PPARGC1B mRNA increases expression
mRNA 23019147
D019833 8496 PPFIBP1
L2
SGT2
hSGT2
hSgt2p
PTPRF interacting protein, binding protein 1 (liprin beta 1) Genistein results in decreased expression of PPFIBP1 mRNA decreases expression
mRNA 23019147
D019833 5493 PPL
periplakin ESR2 promotes the reaction [Genistein results in decreased expression of PPL protein] decreases expression
/ increases reaction
protein 20884965
D019833 5493 PPL
periplakin Genistein results in decreased expression of PPL protein decreases expression
protein 20884965
D019833 333926 PPM1J
PP2CZ
PP2Czeta
PPP2CZ
protein phosphatase, Mg2+/Mn2+ dependent, 1J (EC:3.1.3.16) Genistein results in increased expression of PPM1J mRNA increases expression
mRNA 23019147
D019833 5514 PPP1R10
CAT53
FB19
PNUTS
PP1R10
R111
p99
protein phosphatase 1, regulatory subunit 10 Genistein results in increased expression of PPP1R10 mRNA increases expression
mRNA 20884965
D019833 81706 PPP1R14C
CPI17-like
KEPI
NY-BR-81
protein phosphatase 1, regulatory (inhibitor) subunit 14C Genistein results in increased expression of PPP1R14C mRNA increases expression
mRNA 18847459
D019833 84152 PPP1R1B
DARPP-32
DARPP32
protein phosphatase 1, regulatory (inhibitor) subunit 1B (EC:3.1.3.16) Genistein results in increased expression of PPP1R1B mRNA increases expression
mRNA 23019147
D019833 5521 PPP2R2B
B55BETA
PP2AB55BETA
PP2ABBETA
PP2APR55B
PP2APR55BETA
PR2AB55BETA
PR2ABBETA
PR2APR55BETA
PR52B
PR55-BETA
PR55BETA
SCA12
protein phosphatase 2, regulatory subunit B, beta (EC:3.1.3.16) Genistein results in increased expression of PPP2R2B mRNA increases expression
mRNA 18444173
D019833 5522 PPP2R2C
B55-GAMMA
IMYPNO
IMYPNO1
PR52
PR55G
protein phosphatase 2, regulatory subunit B, gamma (EC:3.1.3.16) Genistein results in increased expression of PPP2R2C mRNA increases expression
mRNA 16474171
D019833 11230 PRAF2
PRA1 domain family, member 2 ESR2 promotes the reaction [Genistein results in decreased expression of PRAF2 protein] decreases expression
/ increases reaction
protein 20884965
D019833 11230 PRAF2
PRA1 domain family, member 2 Genistein results in decreased expression of PRAF2 protein decreases expression
protein 20884965
D019833 9055 PRC1
ASE1
protein regulator of cytokinesis 1 Genistein results in increased expression of PRC1 mRNA increases expression
mRNA 16474171
D019833 5546 PRCC
RCCP1
TPRC
papillary renal cell carcinoma (translocation-associated) Genistein results in decreased expression of PRCC mRNA decreases expression
mRNA 16705744
D019833 57580 PREX1
P-REX1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 ESR2 promotes the reaction [Genistein results in decreased expression of PREX1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 57580 PREX1
P-REX1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Genistein results in decreased expression of PREX1 protein decreases expression
protein 20884965
D019833 5557 PRIM1
p49
primase, DNA, polypeptide 1 (49kDa) (EC:2.7.7.7) Genistein results in increased expression of PRIM1 mRNA increases expression
mRNA 16474171
D019833 5562 PRKAA1
AMPK
AMPKa1
protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31) [Genistein co-treated with Capsaicin] results in increased activity of PRKAA1 protein affects cotreatment
/ increases activity
protein 19723084
D019833 5576 PRKAR2A
PKR2
PRKAR2
protein kinase, cAMP-dependent, regulatory, type II, alpha (EC:2.7.11.1) Genistein results in increased expression of PRKAR2A mRNA increases expression
mRNA 19371625
D019833 5578 PRKCA
AAG6
PKC-alpha
PKCA
PRKACA
protein kinase C, alpha (EC:2.7.11.13) Genistein results in increased expression of PRKCA mRNA increases expression
mRNA 16705744
D019833 5580 PRKCD
MAY1
PKCD
nPKC-delta
protein kinase C, delta (EC:2.7.10.2 2.7.11.13) Genistein results in decreased expression of PRKCD mRNA decreases expression
mRNA 15757668
D019833 3276 PRMT1
ANM1
HCP1
HRMT1L2
IR1B4
protein arginine methyltransferase 1 (EC:2.1.1.125) ESR2 promotes the reaction [Genistein results in increased expression of PRMT1 protein] increases expression
/ increases reaction
protein 20884965
D019833 3276 PRMT1
ANM1
HCP1
HRMT1L2
IR1B4
protein arginine methyltransferase 1 (EC:2.1.1.125) Genistein results in increased expression of PRMT1 protein increases expression
protein 20884965
D019833 5621 PRNP
ASCR
AltPrP
CD230
CJD
GSS
KURU
PRIP
PrP
PrP27-30
PrP33-35C
PrPc
p27-30
prion protein Genistein results in increased expression of PRNP mRNA increases expression
mRNA 18444173
D019833 5627 PROS1
PROS
PS21
PS22
PS23
PS24
PS25
PSA
THPH5
THPH6
protein S (alpha) Genistein results in decreased expression of PROS1 mRNA decreases expression
mRNA 20926118
D019833 10594 PRPF8
HPRP8
PRP8
PRPC8
RP13
SNRNP220
pre-mRNA processing factor 8 Genistein results in decreased expression of PRPF8 mRNA decreases expression
mRNA 16705744
D019833 5644 PRSS1
TRP1
TRY1
TRY4
TRYP1
protease, serine, 1 (trypsin 1) (EC:3.4.21.4) Genistein results in decreased expression of PRSS1 mRNA decreases expression
mRNA 23019147
D019833 11098 PRSS23
SIG13
SPUVE
ZSIG13
protease, serine, 23 ESR1 protein inhibits the reaction [Genistein results in increased expression of PRSS23 mRNA] decreases reaction
/ increases expression
mRNA 23384675
D019833 11098 PRSS23
SIG13
SPUVE
ZSIG13
protease, serine, 23 Genistein results in increased expression of PRSS23 mRNA increases expression
mRNA 23384675
D019833 5652 PRSS8
CAP1
PROSTASIN
protease, serine, 8 ESR2 promotes the reaction [Genistein results in decreased expression of PRSS8 protein] decreases expression
/ increases reaction
protein 20884965
D019833 5652 PRSS8
CAP1
PROSTASIN
protease, serine, 8 Genistein results in decreased expression of PRSS8 protein decreases expression
protein 20884965
D019833 29968 PSAT1
EPIP
PSA
PSAT
phosphoserine aminotransferase 1 (EC:2.6.1.52) Genistein results in increased expression of PSAT1 mRNA increases expression
mRNA 15757668
D019833 5728 PTEN
10q23del
BZS
CWS1
DEC
GLM2
MHAM
MMAC1
PTEN1
TEP1
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) Genistein affects the expression of PTEN mRNA affects expression
mRNA 18431742
D019833 5728 PTEN
10q23del
BZS
CWS1
DEC
GLM2
MHAM
MMAC1
PTEN1
TEP1
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) Genistein affects the expression of PTEN protein affects expression
protein 18431742
D019833 5728 PTEN
10q23del
BZS
CWS1
DEC
GLM2
MHAM
MMAC1
PTEN1
TEP1
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) Genistein inhibits the reaction [HIST3H3 protein modified form binds to PTEN promoter] affects binding
/ decreases reaction
promoter 18431742
D019833 5728 PTEN
10q23del
BZS
CWS1
DEC
GLM2
MHAM
MMAC1
PTEN1
TEP1
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) Genistein results in increased expression of PTEN mRNA increases expression
mRNA 15829497
D019833 5728 PTEN
10q23del
BZS
CWS1
DEC
GLM2
MHAM
MMAC1
PTEN1
TEP1
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) Genistein results in increased expression of PTEN protein increases expression
protein 15829497
D019833 5728 PTEN
10q23del
BZS
CWS1
DEC
GLM2
MHAM
MMAC1
PTEN1
TEP1
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) [[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased activity of FOXO3 protein decreases activity
/ increases activity
/ increases expression
protein 18431742
D019833 5728 PTEN
10q23del
BZS
CWS1
DEC
GLM2
MHAM
MMAC1
PTEN1
TEP1
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) [[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased expression of TP53 protein decreases activity
/ increases expression
protein 18431742
D019833 5731 PTGER1
EP1
prostaglandin E receptor 1 (subtype EP1), 42kDa Genistein results in decreased expression of PTGER1 mRNA decreases expression
mRNA 20706672
D019833 5733 PTGER3
EP3
EP3-I
EP3-II
EP3-III
EP3-IV
EP3e
PGE2-R
prostaglandin E receptor 3 (subtype EP3) Genistein results in increased expression of PTGER3 mRNA increases expression
mRNA 16474171
D019833 145482 PTGR2
PGR2
ZADH1
prostaglandin reductase 2 (EC:1.3.1.48) ESR2 promotes the reaction [Genistein results in increased expression of PTGR2 protein] increases expression
/ increases reaction
protein 20884965
D019833 145482 PTGR2
PGR2
ZADH1
prostaglandin reductase 2 (EC:1.3.1.48) Genistein results in increased expression of PTGR2 protein increases expression
protein 20884965
D019833 5742 PTGS1
COX1
COX3
PCOX1
PES-1
PGG/HS
PGHS-1
PGHS1
PHS1
PTGHS
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Genistein results in decreased expression of PTGS1 mRNA decreases expression
mRNA 20816778
D019833 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Capsaicin promotes the reaction [Genistein results in decreased expression of PTGS2 protein] decreases expression
/ increases reaction
protein 19723084
D019833 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) [Genistein co-treated with arsenic trioxide] results in decreased expression of PTGS2 protein affects cotreatment
/ decreases expression
protein 21078540
D019833 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) [Genistein co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA affects cotreatment
/ increases expression
mRNA 19347870
D019833 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Genistein inhibits the reaction [Fluorouracil results in increased expression of PTGS2 protein] decreases reaction
/ increases expression
protein 15896711
D019833 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) [Genistein inhibits the reaction [Fluorouracil results in increased expression of PTGS2 protein]] which results in decreased abundance of Dinoprostone decreases abundance
/ decreases reaction
/ increases expression
protein 15896711
D019833 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Genistein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA] decreases reaction
/ increases expression
mRNA 16870006
D019833 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Genistein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] decreases reaction
/ increases expression
protein 16870006
D019833 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Genistein inhibits the reaction [TGFA protein results in increased expression of PTGS2 mRNA] decreases reaction
/ increases expression
mRNA 10783318
D019833 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Genistein results in decreased expression of PTGS2 mRNA decreases expression
mRNA 10783318
D019833 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Genistein results in decreased expression of PTGS2 protein decreases expression
protein 19723084
21078540
D019833 5747 PTK2
FADK
FAK
FAK1
FRNK
PPP1R71
p125FAK
pp125FAK
protein tyrosine kinase 2 (EC:2.7.10.2) Genistein results in increased phosphorylation of PTK2 protein increases phosphorylation
protein 12421874
D019833 5763 PTMS
ParaT
parathymosin Genistein results in decreased expression of PTMS mRNA decreases expression
mRNA 16705744
D019833 80324 PUS1
MLASA1
pseudouridylate synthase 1 (EC:5.4.99.12) Genistein results in increased expression of PUS1 mRNA increases expression
mRNA 23019147
D019833 5822 PWP2
EHOC-17
PWP2H
UTP1
PWP2 periodic tryptophan protein homolog (yeast) Genistein results in decreased expression of PWP2 mRNA decreases expression
mRNA 16705744
D019833 5822 PWP2
EHOC-17
PWP2H
UTP1
PWP2 periodic tryptophan protein homolog (yeast) Genistein results in increased expression of PWP2 mRNA increases expression
mRNA 23019147
D019833 5834 PYGB
GPBB
phosphorylase, glycogen; brain (EC:2.4.1.1) ESR2 promotes the reaction [Genistein results in increased expression of PYGB protein] increases expression
/ increases reaction
protein 20884965
D019833 5834 PYGB
GPBB
phosphorylase, glycogen; brain (EC:2.4.1.1) Genistein results in increased expression of PYGB protein increases expression
protein 20884965
D019833 5858 PZP
CPAMD6
pregnancy-zone protein Genistein results in increased expression of PZP mRNA increases expression
mRNA 16705744
D019833 54870 QRICH1
glutamine-rich 1 Genistein inhibits the reaction [Nocodazole results in increased phosphorylation of QRICH1 protein] decreases reaction
/ increases phosphorylation
protein 17510977
D019833 5768 QSOX1
Q6
QSCN6
quiescin Q6 sulfhydryl oxidase 1 (EC:1.8.3.2) Genistein results in increased expression of QSOX1 mRNA increases expression
mRNA 20884965
23019147
D019833 169714 QSOX2
QSCN6L1
SOXN
quiescin Q6 sulfhydryl oxidase 2 (EC:1.8.3.2) Genistein results in increased expression of QSOX2 mRNA increases expression
mRNA 23019147
D019833 9230 RAB11B
H-YPT3
RAB11B, member RAS oncogene family Genistein results in decreased expression of RAB11B mRNA decreases expression
mRNA 16705744
D019833 22931 RAB18
RAB18LI1
WARBM3
RAB18, member RAS oncogene family ESR2 promotes the reaction [Genistein results in increased expression of RAB18 protein] increases expression
/ increases reaction
protein 20884965
D019833 22931 RAB18
RAB18LI1
WARBM3
RAB18, member RAS oncogene family Genistein results in increased expression of RAB18 protein increases expression
protein 20884965
D019833 10244 RABEPK
RAB9P40
bA65N13.1
p40
Rab9 effector protein with kelch motifs Genistein results in increased expression of RABEPK mRNA increases expression
mRNA 23019147
D019833 29127 RACGAP1
CYK4
HsCYK-4
ID-GAP
MgcRacGAP
Rac GTPase activating protein 1 Genistein results in increased expression of RACGAP1 mRNA increases expression
mRNA 16474171
D019833 5886 RAD23A
HHR23A
HR23A
RAD23 homolog A (S. cerevisiae) Genistein results in decreased expression of RAD23A mRNA decreases expression
mRNA 20706672
D019833 5888 RAD51
BRCC5
HRAD51
HsRad51
HsT16930
MRMV2
RAD51A
RECA
RAD51 recombinase Genistein results in increased expression of RAD51 mRNA increases expression
mRNA 16474171
D019833 10635 RAD51AP1
PIR51
RAD51 associated protein 1 Genistein results in increased expression of RAD51AP1 mRNA increases expression
mRNA 16474171
D019833 5889 RAD51C
BROVCA3
FANCO
R51H3
RAD51L2
RAD51 paralog C Genistein results in increased expression of RAD51C mRNA increases expression
mRNA 16474171
D019833 5894 RAF1
CRAF
NS5
Raf-1
c-Raf
v-raf-1 murine leukemia viral oncogene homolog 1 (EC:2.7.11.1) Genistein results in increased phosphorylation of RAF1 protein increases phosphorylation
protein 19038232
D019833 5905 RANGAP1
Fug1
RANGAP
SD
Ran GTPase activating protein 1 Genistein results in decreased expression of RANGAP1 mRNA decreases expression
mRNA 16705744
D019833 51195 RAPGEFL1
Link-GEFII
Rap guanine nucleotide exchange factor (GEF)-like 1 Genistein results in increased expression of RAPGEFL1 mRNA increases expression
mRNA 23019147
D019833 5920 RARRES3
HRASLS4
HRSL4
PLA1/2-3
RIG1
TIG3
retinoic acid receptor responder (tazarotene induced) 3 Genistein results in increased expression of RARRES3 mRNA increases expression
mRNA 15256057
D019833 22821 RASA3
GAP1IP4BP
GAPIII
RAS p21 protein activator 3 Genistein results in increased expression of RASA3 mRNA increases expression
mRNA 23019147
D019833 153020 RASGEF1B
GPIG4
RasGEF domain family, member 1B Genistein results in decreased expression of RASGEF1B mRNA decreases expression
mRNA 23019147
D019833 10125 RASGRP1
CALDAG-GEFI
CALDAG-GEFII
RASGRP
V
hRasGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated) Genistein results in increased expression of RASGRP1 mRNA increases expression
mRNA 23019147
D019833 5925 RB1
OSRC
RB
p105-Rb
pRb
pp110
retinoblastoma 1 Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein decreases activity
/ increases phosphorylation
protein 17051425
D019833 5925 RB1
OSRC
RB
p105-Rb
pRb
pp110
retinoblastoma 1 lycopene inhibits the reaction [Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein] decreases activity
/ decreases reaction
/ increases phosphorylation
protein 17051425
D019833 5932 RBBP8
COM1
CTIP
JWDS
RIM
SAE2
SCKL2
retinoblastoma binding protein 8 Genistein results in increased expression of RBBP8 mRNA increases expression
mRNA 15757668
23019147
D019833 31818 Genistein results in increased expression of RBM13 mRNA increases expression
mRNA 19371625
D019833 5947 RBP1
CRABP-I
CRBP
CRBP1
CRBPI
RBPC
retinol binding protein 1, cellular Genistein results in decreased expression of RBP1 mRNA decreases expression
mRNA 19371625
D019833 5950 RBP4
RDCCAS
retinol binding protein 4, plasma Genistein results in increased expression of RBP4 mRNA increases expression
mRNA 20884965
D019833 5954 RCN1
PIG20
RCAL
RCN
reticulocalbin 1, EF-hand calcium binding domain ESR1 promotes the reaction [Genistein results in increased expression of RCN1 protein] increases expression
/ increases reaction
protein 20884965
D019833 5954 RCN1
PIG20
RCAL
RCN
reticulocalbin 1, EF-hand calcium binding domain Genistein results in increased expression of RCN1 protein increases expression
protein 20884965
D019833 7905 REEP5
C5orf18
D5S346
DP1
TB2
YOP1
receptor accessory protein 5 ESR2 promotes the reaction [Genistein results in decreased expression of REEP5 protein] decreases expression
/ increases reaction
protein 20884965
D019833 7905 REEP5
C5orf18
D5S346
DP1
TB2
YOP1
receptor accessory protein 5 ESR2 promotes the reaction [Genistein results in increased expression of REEP5 protein] increases expression
/ increases reaction
protein 20884965
D019833 7905 REEP5
C5orf18
D5S346
DP1
TB2
YOP1
receptor accessory protein 5 Genistein results in decreased expression of REEP5 protein decreases expression
protein 20884965
D019833 7905 REEP5
C5orf18
D5S346
DP1
TB2
YOP1
receptor accessory protein 5 Genistein results in increased expression of REEP5 protein increases expression
protein 20884965
D019833 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A Genistein affects the localization of RELA protein affects localization
protein 18431742
D019833 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A Genistein promotes the reaction [arsenic trioxide results in decreased expression of RELA protein] decreases expression
/ increases reaction
protein 21078540
D019833 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A Genistein results in decreased expression of RELA protein decreases expression
protein 21078540
D019833 6001 RGS10
regulator of G-protein signaling 10 Genistein results in increased expression of RGS10 mRNA increases expression
mRNA 19371625
23019147
D019833 6004 RGS16
A28-RGS14
A28-RGS14P
RGS-R
regulator of G-protein signaling 16 Genistein results in decreased expression of RGS16 mRNA decreases expression
mRNA 15256057
D019833 9886 RHOBTB1
Rho-related BTB domain containing 1 Genistein results in increased expression of RHOBTB1 mRNA increases expression
mRNA 23019147
D019833 58480 RHOU
ARHU
CDC42L1
DJ646B12.2
WRCH1
fJ646B12.2
hG28K
ras homolog family member U Genistein results in increased expression of RHOU mRNA increases expression
mRNA 23019147
D019833 116028 RMI2
BLAP18
C16orf75
RecQ mediated genome instability 2 Genistein results in decreased expression of RMI2 mRNA decreases expression
mRNA 19371625
D019833 246243 RNASEH1
H1RNA
RNH1
ribonuclease H1 (EC:3.1.26.4) Genistein results in increased expression of RNASEH1 mRNA increases expression
mRNA 16474171
D019833 8635 RNASET2
RNASE6PL
bA514O12.3
ribonuclease T2 (EC:3.1.27.1) Genistein results in increased expression of RNASET2 mRNA increases expression
mRNA 20884965
D019833 84900 RNFT2
TMEM118
ring finger protein, transmembrane 2 Genistein results in increased expression of RNFT2 mRNA increases expression
mRNA 18847459
D019833 55178 RNMTL1
RNA methyltransferase like 1 (EC:2.1.1.-) ESR2 promotes the reaction [Genistein results in increased expression of RNMTL1 protein] increases expression
/ increases reaction
protein 20884965
D019833 55178 RNMTL1
RNA methyltransferase like 1 (EC:2.1.1.-) Genistein results in increased expression of RNMTL1 protein increases expression
protein 20884965
D019833 6051 RNPEP
arginyl aminopeptidase (aminopeptidase B) (EC:3.4.11.6) ESR2 promotes the reaction [Genistein results in increased expression of RNPEP protein] increases expression
/ increases reaction
protein 20884965
D019833 6051 RNPEP
arginyl aminopeptidase (aminopeptidase B) (EC:3.4.11.6) Genistein results in increased expression of RNPEP protein increases expression
protein 20884965
D019833 83853 ROPN1L
ASP
RSPH11
rhophilin associated tail protein 1-like Genistein results in increased expression of ROPN1L mRNA increases expression
mRNA 18847459
D019833 130773 ESR1 promotes the reaction [Genistein results in increased expression of RPL23AP37 protein] increases expression
/ increases reaction
protein 20884965
D019833 130773 Genistein results in increased expression of RPL23AP37 protein increases expression
protein 20884965
D019833 6158 RPL28
L28
ribosomal protein L28 (EC:3.6.5.3) Genistein results in increased expression of RPL28 mRNA increases expression
mRNA 18847459
D019833 6169 RPL38
L38
ribosomal protein L38 ESR2 promotes the reaction [Genistein results in decreased expression of RPL38 protein] decreases expression
/ increases reaction
protein 20884965
D019833 6169 RPL38
L38
ribosomal protein L38 Genistein results in decreased expression of RPL38 protein decreases expression
protein 20884965
D019833 6205 RPS11
S11
ribosomal protein S11 Genistein results in decreased expression of RPS11 mRNA decreases expression
mRNA 15256057
D019833 6217 RPS16
S16
ribosomal protein S16 ESR1 promotes the reaction [Genistein results in decreased expression of RPS16 protein] decreases expression
/ increases reaction
protein 20884965
D019833 6217 RPS16
S16
ribosomal protein S16 Genistein results in decreased expression of RPS16 protein decreases expression
protein 20884965
D019833 6222 RPS18
D6S218E
HKE3
KE-3
KE3
S18
ribosomal protein S18 ESR1 promotes the reaction [Genistein results in decreased expression of RPS18 protein] decreases expression
/ increases reaction
protein 20884965
D019833 6222 RPS18
D6S218E
HKE3
KE-3
KE3
S18
ribosomal protein S18 Genistein results in decreased expression of RPS18 protein decreases expression
protein 20884965
D019833 6223 RPS19
DBA
DBA1
S19
ribosomal protein S19 Genistein results in decreased expression of RPS19 mRNA decreases expression
mRNA 15256057
D019833 6230 RPS25
S25
ribosomal protein S25 ESR1 promotes the reaction [Genistein results in decreased expression of RPS25 protein] decreases expression
/ increases reaction
protein 20884965
D019833 6230 RPS25
S25
ribosomal protein S25 Genistein results in decreased expression of RPS25 protein decreases expression
protein 20884965
D019833 6235 RPS29
S29
ribosomal protein S29 ESR1 promotes the reaction [Genistein results in decreased expression of RPS29 protein] decreases expression
/ increases reaction
protein 20884965
D019833 6235 RPS29
S29
ribosomal protein S29 Genistein results in decreased expression of RPS29 protein decreases expression
protein 20884965
D019833 6197 RPS6KA3
CLS
HU-3
ISPK-1
MAPKAPK1B
MRX19
RSK
RSK2
S6K-alpha3
p90-RSK2
pp90RSK2
ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1) Genistein results in increased expression of RPS6KA3 mRNA increases expression
mRNA 15757668
D019833 6236 RRAD
RAD
RAD1
REM3
Ras-related associated with diabetes Genistein results in decreased expression of RRAD mRNA decreases expression
mRNA 15257099
D019833 6241 RRM2
R2
RR2
RR2M
ribonucleotide reductase M2 (EC:1.17.4.1) Genistein results in increased expression of RRM2 mRNA increases expression
mRNA 16474171
20884965
D019833 50484 RRM2B
MTDPS8A
MTDPS8B
P53R2
ribonucleotide reductase M2 B (TP53 inducible) (EC:1.17.4.1) Genistein results in increased expression of RRM2B mRNA increases expression
mRNA 18847459
D019833 23223 RRP12
KIAA0690
ribosomal RNA processing 12 homolog (S. cerevisiae) Genistein results in increased expression of RRP12 mRNA increases expression
mRNA 23019147
D019833 9136 RRP9
RNU3IP2
U3-55K
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) Genistein results in increased expression of RRP9 mRNA increases expression
mRNA 23019147
D019833 23212 RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) Genistein results in decreased expression of RRS1 mRNA decreases expression
mRNA 20884965
D019833 23212 RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) Genistein results in increased expression of RRS1 mRNA increases expression
mRNA 23019147
D019833 6256 RXRA
NR2B1
retinoid X receptor, alpha Genistein promotes the reaction [RXRA protein binds to ABCC2 promoter] affects binding
/ increases reaction
protein 21689630
D019833 6256 RXRA
NR2B1
retinoid X receptor, alpha Genistein results in decreased expression of RXRA mRNA decreases expression
mRNA 20706672
D019833 6256 RXRA
NR2B1
retinoid X receptor, alpha resveratrol inhibits the reaction [Genistein promotes the reaction [RXRA protein binds to ABCC2 promoter]] affects binding
/ decreases reaction
/ increases reaction
protein 21689630
D019833 140576 S100A16
DT1P1A7
S100F
S100 calcium binding protein A16 ESR2 promotes the reaction [Genistein results in decreased expression of S100A16 protein] decreases expression
/ increases reaction
protein 20884965
D019833 140576 S100A16
DT1P1A7
S100F
S100 calcium binding protein A16 Genistein results in decreased expression of S100A16 protein decreases expression
protein 20884965
D019833 6279 S100A8
60B8AG
CAGA
CFAG
CGLA
CP-10
L1Ag
MA387
MIF
MRP8
NIF
P8
S100 calcium binding protein A8 ESR1 promotes the reaction [Genistein results in decreased expression of S100A8 protein] decreases expression
/ increases reaction
protein 20884965
D019833 6279 S100A8
60B8AG
CAGA
CFAG
CGLA
CP-10
L1Ag
MA387
MIF
MRP8
NIF
P8
S100 calcium binding protein A8 ESR2 promotes the reaction [Genistein results in decreased expression of S100A8 protein] decreases expression
/ increases reaction
protein 20884965
D019833 6279 S100A8
60B8AG
CAGA
CFAG
CGLA
CP-10
L1Ag
MA387
MIF
MRP8
NIF
P8
S100 calcium binding protein A8 Genistein results in decreased expression of S100A8 protein decreases expression
protein 20884965
D019833 6280 S100A9
60B8AG
CAGB
CFAG
CGLB
L1AG
LIAG
MAC387
MIF
MRP14
NIF
P14
S100 calcium binding protein A9 ESR1 promotes the reaction [Genistein results in decreased expression of S100A9 protein] decreases expression
/ increases reaction
protein 20884965
D019833 6280 S100A9
60B8AG
CAGB
CFAG
CGLB
L1AG
LIAG
MAC387
MIF
MRP14
NIF
P14
S100 calcium binding protein A9 ESR2 promotes the reaction [Genistein results in increased expression of S100A9 protein] increases expression
/ increases reaction
protein 20884965
D019833 6280 S100A9
60B8AG
CAGB
CFAG
CGLB
L1AG
LIAG
MAC387
MIF
MRP14
NIF
P14
S100 calcium binding protein A9 Genistein results in decreased expression of S100A9 protein decreases expression
protein 20884965
D019833 6280 S100A9
60B8AG
CAGB
CFAG
CGLB
L1AG
LIAG
MAC387
MIF
MRP14
NIF
P14
S100 calcium binding protein A9 Genistein results in increased expression of S100A9 protein increases expression
protein 20884965
D019833 1903 S1PR3
EDG-3
EDG3
LPB3
S1P3
sphingosine-1-phosphate receptor 3 Genistein results in increased expression of S1PR3 mRNA increases expression
mRNA 19371625
D019833 29901 SAC3D1
HSU79266
SHD1
SAC3 domain containing 1 Genistein results in increased expression of SAC3D1 mRNA increases expression
mRNA 16474171
D019833 6299 SALL1
HSAL1
Sal-1
TBS
ZNF794
spalt-like transcription factor 1 Genistein results in increased expression of SALL1 mRNA increases expression
mRNA 23019147
D019833 45384 Genistein results in decreased expression of SAT mRNA decreases expression
mRNA 19371625
D019833 6309 SC5D
ERG3
S5DES
SC5DL
sterol-C5-desaturase (EC:1.14.21.6) Genistein results in decreased expression of SC5D mRNA decreases expression
mRNA 20816778
D019833 6319 SCD
FADS5
MSTP008
SCD1
SCDOS
stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) Genistein results in decreased expression of SCD mRNA decreases expression
mRNA 15257099
20816778
D019833 6319 SCD
FADS5
MSTP008
SCD1
SCDOS
stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) Genistein results in increased expression of SCD mRNA increases expression
mRNA 15378649
18847459
D019833 8796 SCEL
sciellin Genistein results in decreased expression of SCEL mRNA decreases expression
mRNA 23019147
D019833 29970 SCHIP1
SCHIP-1
schwannomin interacting protein 1 Genistein results in decreased expression of SCHIP1 mRNA decreases expression
mRNA 20884965
D019833 6334 SCN8A
CERIII
CIAT
EIEE13
MED
NaCh6
Nav1.6
PN4
sodium channel, voltage gated, type VIII, alpha subunit Genistein results in decreased expression of SCN8A mRNA decreases expression
mRNA 16705744
D019833 6390 SDHB
CWS2
IP
PGL4
SDH
SDH1
SDH2
SDHIP
succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (EC:1.3.5.1) ESR2 promotes the reaction [Genistein results in decreased expression of SDHB protein] decreases expression
/ increases reaction
protein 20884965
D019833 6390 SDHB
CWS2
IP
PGL4
SDH
SDH1
SDH2
SDHIP
succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (EC:1.3.5.1) Genistein results in decreased expression of SDHB protein decreases expression
protein 20884965
D019833 9871 SEC24D
SEC24 family member D Genistein results in increased expression of SEC24D mRNA increases expression
mRNA 15378649
D019833 29927 SEC61A1
HSEC61
SEC61
SEC61A
Sec61 alpha 1 subunit (S. cerevisiae) Genistein results in decreased expression of SEC61A1 mRNA decreases expression
mRNA 16705744
D019833 8991 SELENBP1
LPSB
SBP56
SP56
hSBP
selenium binding protein 1 Genistein results in decreased expression of SELENBP1 mRNA decreases expression
mRNA 15159206
D019833 22929 SEPHS1
SELD
SPS
SPS1
selenophosphate synthetase 1 (EC:2.7.9.3) ESR1 promotes the reaction [Genistein results in decreased expression of SEPHS1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 22929 SEPHS1
SELD
SPS
SPS1
selenophosphate synthetase 1 (EC:2.7.9.3) ESR2 promotes the reaction [Genistein results in increased expression of SEPHS1 protein] increases expression
/ increases reaction
protein 20884965
D019833 22929 SEPHS1
SELD
SPS
SPS1
selenophosphate synthetase 1 (EC:2.7.9.3) Genistein results in decreased expression of SEPHS1 protein decreases expression
protein 20884965
D019833 22929 SEPHS1
SELD
SPS
SPS1
selenophosphate synthetase 1 (EC:2.7.9.3) Genistein results in increased expression of SEPHS1 protein increases expression
protein 20884965
D019833 5265 SERPINA1
A1A
A1AT
AAT
PI
PI1
PRO2275
alpha1AT
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 Genistein results in decreased expression of SERPINA1 mRNA decreases expression
mRNA 18444173
D019833 5265 SERPINA1
A1A
A1AT
AAT
PI
PI1
PRO2275
alpha1AT
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 Genistein results in increased expression of SERPINA1 mRNA increases expression
mRNA 20884965
D019833 5054 SERPINE1
PAI
PAI-1
PAI1
PLANH1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 Genistein inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein] decreases reaction
/ increases secretion
protein 14534369
D019833 5054 SERPINE1
PAI
PAI-1
PAI1
PLANH1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 Genistein promotes the reaction [troglitazone inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein]] decreases reaction
/ increases reaction
/ increases secretion
protein 14534369
D019833 27244 SESN1
PA26
SEST1
sestrin 1 Genistein results in increased expression of SESN1 mRNA increases expression
mRNA 18847459
D019833 83443 SF3B5
SF3b10
Ysf3
splicing factor 3b, subunit 5, 10kDa Genistein results in increased expression of SF3B5 mRNA increases expression
mRNA 19371625
D019833 6424 SFRP4
FRP-4
FRPHE
sFRP-4
secreted frizzled-related protein 4 Genistein results in decreased expression of SFRP4 mRNA decreases expression
mRNA 15256057
D019833 118980 SFXN2
sideroflexin 2 Genistein results in increased expression of SFXN2 mRNA increases expression
mRNA 16474171
D019833 6446 SGK1
SGK
serum/glucocorticoid regulated kinase 1 (EC:2.7.11.1) Genistein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SGK1 mRNA] decreases reaction
/ increases expression
mRNA 21056929
D019833 6446 SGK1
SGK
serum/glucocorticoid regulated kinase 1 (EC:2.7.11.1) Genistein results in decreased expression of SGK1 mRNA decreases expression
mRNA 21056929
D019833 81537 SGPP1
SPPase1
sphingosine-1-phosphate phosphatase 1 [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of SGPP1 mRNA affects cotreatment
/ decreases expression
mRNA 16963248
D019833 6462 SHBG
ABP
SBP
TEBG
sex hormone-binding globulin Genistein results in increased expression of SHBG mRNA increases expression
mRNA 18847459
D019833 6474 SHOX2
OG12
OG12X
SHOT
short stature homeobox 2 Genistein results in decreased expression of SHOX2 mRNA decreases expression
mRNA 15256057
D019833 6478 SIAH2
hSiah2
siah E3 ubiquitin protein ligase 2 (EC:6.3.2.-) Genistein results in increased expression of SIAH2 mRNA increases expression
mRNA 23019147
D019833 23411 SIRT1
SIR2L1
sirtuin 1 Genistein affects the localization of SIRT1 protein affects localization
protein 18431742
D019833 23411 SIRT1
SIR2L1
sirtuin 1 Genistein inhibits the reaction [SIRT1 protein binds to FOXO3 promoter] affects binding
/ decreases reaction
protein 18431742
D019833 23411 SIRT1
SIR2L1
sirtuin 1 Genistein inhibits the reaction [SIRT1 protein binds to TP53 promoter] affects binding
/ decreases reaction
protein 18431742
D019833 23411 SIRT1
SIR2L1
sirtuin 1 [Genistein results in decreased activity of SIRT1 protein] which results in decreased acetylation of HIST3H3 protein decreases acetylation
/ decreases activity
protein 18431742
D019833 23411 SIRT1
SIR2L1
sirtuin 1 Genistein results in decreased expression of SIRT1 mRNA decreases expression
mRNA 18431742
D019833 6558 SLC12A2
BSC
BSC2
NKCC1
solute carrier family 12 (sodium/potassium/chloride transporter), member 2 Genistein results in decreased expression of SLC12A2 mRNA decreases expression
mRNA 15159206
15757668
D019833 6560 SLC12A4
KCC1
solute carrier family 12 (potassium/chloride transporter), member 4 Genistein results in decreased expression of SLC12A4 mRNA decreases expression
mRNA 16705744
D019833 9123 SLC16A3
MCT_3
MCT_4
MCT-3
MCT-4
MCT3
MCT4
solute carrier family 16 (monocarboxylate transporter), member 3 Genistein results in increased expression of SLC16A3 mRNA increases expression
mRNA 23019147
D019833 6573 SLC19A1
CHMD
FOLT
IFC1
REFC
RFC1
solute carrier family 19 (folate transporter), member 1 Genistein results in increased expression of SLC19A1 mRNA increases expression
mRNA 23019147
D019833 6509 SLC1A4
ASCT1
SATT
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 Genistein results in increased expression of SLC1A4 mRNA increases expression
mRNA 15757668
D019833 6510 SLC1A5
AAAT
ASCT2
ATBO
M7V1
M7VS1
R16
RDRC
solute carrier family 1 (neutral amino acid transporter), member 5 Genistein results in increased expression of SLC1A5 mRNA increases expression
mRNA 19371625
23019147
D019833 51310 SLC22A17
24p3R
BOCT
BOIT
NGALR
NGALR2
NGALR3
hBOIT
solute carrier family 22, member 17 Genistein results in increased expression of SLC22A17 mRNA increases expression
mRNA 18847459
D019833 6584 SLC22A5
CDSP
OCTN2
OCTN2VT
solute carrier family 22 (organic cation/carnitine transporter), member 5 Genistein results in increased expression of SLC22A5 mRNA increases expression
mRNA 23019147
D019833 9962 SLC23A2
NBTL1
SLC23A1
SVCT2
YSPL2
solute carrier family 23 (ascorbic acid transporter), member 2 Genistein inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid] decreases reaction
/ increases uptake
protein 17092984
D019833 60386 SLC25A19
DNC
MCPHA
MUP1
THMD3
THMD4
TPC
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 Genistein results in increased expression of SLC25A19 mRNA increases expression
mRNA 23019147
D019833 79751 SLC25A22
EIEE3
GC1
NET44
solute carrier family 25 (mitochondrial carrier: glutamate), member 22 Genistein results in increased expression of SLC25A22 mRNA increases expression
mRNA 23019147
D019833 115111 SLC26A7
SUT2
solute carrier family 26 (anion exchanger), member 7 Genistein results in decreased expression of SLC26A7 mRNA decreases expression
mRNA 23019147
D019833 6513 SLC2A1
DYT17
DYT18
DYT9
EIG12
GLUT
GLUT1
GLUT1DS
HTLVR
PED
solute carrier family 2 (facilitated glucose transporter), member 1 Genistein inhibits the reaction [SLC2A1 protein affects the transport of Glucose] affects transport
/ decreases reaction
protein 14642735
D019833 6513 SLC2A1
DYT17
DYT18
DYT9
EIG12
GLUT
GLUT1
GLUT1DS
HTLVR
PED
solute carrier family 2 (facilitated glucose transporter), member 1 Genistein results in decreased activity of SLC2A1 protein decreases activity
protein 14642735
D019833 7779 SLC30A1
ZNT1
ZRC1
solute carrier family 30 (zinc transporter), member 1 Genistein results in increased expression of SLC30A1 mRNA increases expression
mRNA 18847459
23019147
D019833 1317 SLC31A1
COPT1
CTR1
solute carrier family 31 (copper transporter), member 1 Genistein results in increased expression of SLC31A1 mRNA increases expression
mRNA 19371625
D019833 64116 SLC39A8
BIGM103
LZT-Hs6
ZIP8
solute carrier family 39 (zinc transporter), member 8 Genistein results in increased expression of SLC39A8 mRNA increases expression
mRNA 16474171
D019833 6520 SLC3A2
4F2
4F2HC
4T2HC
CD98
CD98HC
MDU1
NACAE
solute carrier family 3 (amino acid transporter heavy chain), member 2 ESR1 promotes the reaction [Genistein results in increased expression of SLC3A2 protein] increases expression
/ increases reaction
protein 20884965
D019833 6520 SLC3A2
4F2
4F2HC
4T2HC
CD98
CD98HC
MDU1
NACAE
solute carrier family 3 (amino acid transporter heavy chain), member 2 Genistein results in increased expression of SLC3A2 mRNA increases expression
mRNA 19371625
23019147
D019833 6520 SLC3A2
4F2
4F2HC
4T2HC
CD98
CD98HC
MDU1
NACAE
solute carrier family 3 (amino acid transporter heavy chain), member 2 Genistein results in increased expression of SLC3A2 protein increases expression
protein 20884965
D019833 146802 SLC47A2
MATE2
MATE2-B
MATE2-K
MATE2K
solute carrier family 47 (multidrug and toxin extrusion), member 2 Genistein results in increased expression of SLC47A2 mRNA increases expression
mRNA 23019147
D019833 6528 SLC5A5
NIS
TDH1
solute carrier family 5 (sodium/iodide cotransporter), member 5 Genistein results in increased expression of SLC5A5 mRNA increases expression
mRNA 21738342
D019833 8884 SLC5A6
SMVT
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 Genistein results in increased expression of SLC5A6 mRNA increases expression
mRNA 23019147
D019833 6539 SLC6A12
BGT-1
BGT1
GAT2
solute carrier family 6 (neurotransmitter transporter), member 12 Genistein results in increased expression of SLC6A12 mRNA increases expression
mRNA 23019147
D019833 11254 SLC6A14
BMIQ11
solute carrier family 6 (amino acid transporter), member 14 Genistein results in increased expression of SLC6A14 mRNA increases expression
mRNA 11331657
16474171
D019833 6533 SLC6A6
TAUT
solute carrier family 6 (neurotransmitter transporter), member 6 Genistein results in increased expression of SLC6A6 mRNA increases expression
mRNA 19371625
23019147
D019833 23657 SLC7A11
CCBR1
xCT
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 Genistein results in decreased expression of SLC7A11 mRNA decreases expression
mRNA 16474171
D019833 8140 SLC7A5
4F2LC
CD98
D16S469E
E16
LAT1
MPE16
hLAT1
solute carrier family 7 (amino acid transporter light chain, L system), member 5 ESR1 promotes the reaction [Genistein results in increased expression of SLC7A5 protein] increases expression
/ increases reaction
protein 20884965
D019833 8140 SLC7A5
4F2LC
CD98
D16S469E
E16
LAT1
MPE16
hLAT1
solute carrier family 7 (amino acid transporter light chain, L system), member 5 Genistein results in increased expression of SLC7A5 mRNA increases expression
mRNA 15757668
23019147
D019833 8140 SLC7A5
4F2LC
CD98
D16S469E
E16
LAT1
MPE16
hLAT1
solute carrier family 7 (amino acid transporter light chain, L system), member 5 Genistein results in increased expression of SLC7A5 protein increases expression
protein 20884965
D019833 81893 SLC7A5P1
DC49
LAT1-3TM
MLAS
hLAT1-3TM
solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1 Genistein results in increased expression of SLC7A5P1 mRNA increases expression
mRNA 23019147
D019833 387254 SLC7A5P2
IMAA
MMAA
solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2 Genistein results in increased expression of SLC7A5P2 mRNA increases expression
mRNA 23019147
D019833 9368 SLC9A3R1
EBP50
NHERF
NHERF-1
NHERF1
NPHLOP2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 ESR2 promotes the reaction [Genistein results in increased expression of SLC9A3R1 protein] increases expression
/ increases reaction
protein 20884965
D019833 9368 SLC9A3R1
EBP50
NHERF
NHERF-1
NHERF1
NPHLOP2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 Genistein results in increased expression of SLC9A3R1 mRNA increases expression
mRNA 23019147
D019833 9368 SLC9A3R1
EBP50
NHERF
NHERF-1
NHERF1
NPHLOP2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 Genistein results in increased expression of SLC9A3R1 protein increases expression
protein 20884965
D019833 6578 SLCO2A1
MATR1
OATP2A1
PGT
PHOAR2
SLC21A2
solute carrier organic anion transporter family, member 2A1 Genistein results in increased expression of SLCO2A1 mRNA increases expression
mRNA 19371625
23019147
D019833 162394 SLFN5
schlafen family member 5 Genistein results in increased expression of SLFN5 mRNA increases expression
mRNA 18847459
D019833 6586 SLIT3
MEGF5
SLIL2
SLIT1
Slit-3
slit2
slit homolog 3 (Drosophila) Genistein results in increased expression of SLIT3 mRNA increases expression
mRNA 23019147
D019833 9748 SLK
LOSK
STK2
bA16H23.1
se20-9
STE20-like kinase (EC:2.7.11.1) ESR2 promotes the reaction [Genistein results in decreased expression of SLK protein] decreases expression
/ increases reaction
protein 20884965
D019833 9748 SLK
LOSK
STK2
bA16H23.1
se20-9
STE20-like kinase (EC:2.7.11.1) Genistein results in decreased expression of SLK protein decreases expression
protein 20884965
D019833 57228 SMAGP
hSMAGP
small cell adhesion glycoprotein Genistein results in decreased expression of SMAGP mRNA decreases expression
mRNA 19371625
D019833 6597 SMARCA4
BAF190
BAF190A
BRG1
MRD16
RTPS2
SNF2
SNF2L4
SNF2LB
SWI2
hSNF2b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Genistein results in increased expression of SMARCA4 mRNA increases expression
mRNA 16705744
D019833 10592 SMC2
CAP-E
CAPE
SMC-2
SMC2L1
structural maintenance of chromosomes 2 Genistein results in increased expression of SMC2 mRNA increases expression
mRNA 16474171
D019833 10051 SMC4
CAP-C
CAPC
SMC-4
SMC4L1
hCAP-C
structural maintenance of chromosomes 4 Genistein results in increased expression of SMC4 mRNA increases expression
mRNA 16474171
D019833 23137 SMC5
SMC5L1
structural maintenance of chromosomes 5 Genistein results in decreased expression of SMC5 mRNA decreases expression
mRNA 16705744
D019833 23049 SMG1
61E3.4
ATX
LIP
SMG1 phosphatidylinositol 3-kinase-related kinase (EC:2.7.11.1) Genistein results in decreased expression of SMG1 mRNA decreases expression
mRNA 16705744
D019833 23049 SMG1
61E3.4
ATX
LIP
SMG1 phosphatidylinositol 3-kinase-related kinase (EC:2.7.11.1) Genistein results in increased expression of SMG1 mRNA increases expression
mRNA 23019147
D019833 201895 SMIM14
C4orf34
small integral membrane protein 14 Genistein results in decreased expression of SMIM14 mRNA decreases expression
mRNA 23019147
D019833 54498 SMOX
C20orf16
PAO
PAO-1
PAOH1
SMO
spermine oxidase (EC:1.5.3.16) Genistein results in increased expression of SMOX mRNA increases expression
mRNA 23019147
D019833 724102 SNHG4
NCRNA00059
U19H
small nucleolar RNA host gene 4 (non-protein coding) Genistein results in increased expression of SNHG4 mRNA increases expression
mRNA 23019147
D019833 677838 SNORA61
ACA61
small nucleolar RNA, H/ACA box 61 Genistein results in increased expression of SNORA61 mRNA increases expression
mRNA 23019147
D019833 6043 SNORA63
E3
E3-2
RNE3
RNU107
small nucleolar RNA, H/ACA box 63 Genistein results in increased expression of SNORA63 mRNA increases expression
mRNA 23019147
D019833 6626 SNRPA
Mud1
U1-A
U1A
small nuclear ribonucleoprotein polypeptide A Genistein results in decreased expression of SNRPA mRNA decreases expression
mRNA 16705744
D019833 9021 SOCS3
ATOD4
CIS3
Cish3
SOCS-3
SSI-3
SSI3
suppressor of cytokine signaling 3 fulvestrant inhibits the reaction [Genistein results in increased expression of SOCS3 mRNA] decreases reaction
/ increases expression
mRNA 16055089
D019833 9021 SOCS3
ATOD4
CIS3
Cish3
SOCS-3
SSI-3
SSI3
suppressor of cytokine signaling 3 Genistein results in increased expression of SOCS3 mRNA increases expression
mRNA 16055089
D019833 6647 SOD1
ALS
ALS1
IPOA
SOD
hSod1
homodimer
superoxide dismutase 1, soluble (EC:1.15.1.1) Genistein results in increased expression of SOD1 mRNA increases expression
mRNA 18686095
D019833 6648 SOD2
IPOB
MNSOD
MVCD6
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) Genistein inhibits the reaction [TNF protein results in increased activity of SOD2 protein] decreases reaction
/ increases activity
protein 9372618
D019833 6648 SOD2
IPOB
MNSOD
MVCD6
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) Genistein inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA] decreases reaction
/ increases expression
mRNA 9372618
D019833 6648 SOD2
IPOB
MNSOD
MVCD6
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) Genistein results in decreased expression of SOD2 mRNA decreases expression
mRNA 20816778
D019833 6649 SOD3
EC-SOD
superoxide dismutase 3, extracellular (EC:1.15.1.1) Genistein results in decreased expression of SOD3 mRNA decreases expression
mRNA 20706672
D019833 10580 SORBS1
CAP
FLAF2
R85FL
SH3D5
SH3P12
SORB1
sorbin and SH3 domain containing 1 Genistein results in increased expression of SORBS1 mRNA increases expression
mRNA 18847459
D019833 6652 SORD
SORD1
sorbitol dehydrogenase (EC:1.1.1.14) Genistein results in decreased expression of SORD mRNA decreases expression
mRNA 15378649
D019833 6657 SOX2
ANOP3
MCOPS3
SRY (sex determining region Y)-box 2 Genistein results in decreased expression of SOX2 mRNA decreases expression
mRNA 16474171
D019833 6659 SOX4
EVI16
SRY (sex determining region Y)-box 4 Genistein results in decreased expression of SOX4 mRNA decreases expression
mRNA 16474171
D019833 6667 SP1
Sp1 transcription factor Genistein promotes the reaction [SP1 protein binds to VDR promoter] affects binding
/ increases reaction
protein 17088408
D019833 6667 SP1
Sp1 transcription factor Genistein results in increased activity of SP1 protein increases activity
protein 17088408
D019833 6667 SP1
Sp1 transcription factor U 0126 inhibits the reaction [Genistein results in increased activity of SP1 protein] decreases reaction
/ increases activity
protein 17088408
D019833 79582 SPAG16
PF20
WDR29
sperm associated antigen 16 Genistein results in decreased expression of SPAG16 mRNA decreases expression
mRNA 23019147
D019833 10615 SPAG5
DEEPEST
MAP126
hMAP126
sperm associated antigen 5 Genistein affects the expression of SPAG5 mRNA affects expression
mRNA 18847459
D019833 124044 SPATA2L
C16orf76
tamo
spermatogenesis associated 2-like Genistein results in decreased expression of SPATA2L mRNA decreases expression
mRNA 16705744
D019833 25803 SPDEF
PDEF
RP11-375E1__A.3
bA375E1.3
SAM pointed domain containing ETS transcription factor Genistein results in decreased expression of SPDEF mRNA decreases expression
mRNA 15378649
D019833 10927 SPIN1
SPIN
spindlin 1 Genistein results in decreased expression of SPIN1 mRNA decreases expression
mRNA 16705744
D019833 90864 SPSB3
C16orf31
SSB3
splA/ryanodine receptor domain and SOCS box containing 3 Genistein results in decreased expression of SPSB3 mRNA decreases expression
mRNA 19371625
D019833 6713 SQLE
squalene epoxidase (EC:1.14.13.132) Genistein results in decreased expression of SQLE mRNA decreases expression
mRNA 19371625
D019833 8878 SQSTM1
A170
OSIL
PDB3
ZIP3
p60
p62
p62B
sequestosome 1 Genistein results in decreased expression of SQSTM1 mRNA decreases expression
mRNA 16474171
D019833 136853 SRCRB4D
S4D-SRCRB
SRCRB-S4D
SSC4D
scavenger receptor cysteine rich domain containing, group B (4 domains) Genistein results in decreased expression of SRCRB4D mRNA decreases expression
mRNA 19371625
D019833 6716 SRD5A2
steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC:1.3.1.22) Genistein results in decreased expression of SRD5A2 mRNA decreases expression
mRNA 20706672
D019833 79644 SRD5A3
CDG1P
CDG1Q
KRIZI
SRD5A2L
SRD5A2L1
steroid 5 alpha-reductase 3 (EC:1.3.1.22 1.3.1.94) Genistein results in increased expression of SRD5A3 mRNA increases expression
mRNA 20884965
D019833 6723 SRM
PAPT
SPDSY
SPS1
SRML1
spermidine synthase (EC:2.5.1.16) Genistein results in increased expression of SRM mRNA increases expression
mRNA 23019147
D019833 6734 SRPR
DP
Sralpha
signal recognition particle receptor (docking protein) ESR2 promotes the reaction [Genistein results in decreased expression of SRPR protein] decreases expression
/ increases reaction
protein 20884965
D019833 6734 SRPR
DP
Sralpha
signal recognition particle receptor (docking protein) Genistein results in decreased expression of SRPR protein decreases expression
protein 20884965
D019833 140809 SRXN1
C20orf139
Npn3
SRX
SRX1
sulfiredoxin 1 (EC:1.8.98.2) Genistein results in increased expression of SRXN1 mRNA increases expression
mRNA 18847459
D019833 6770 STAR
STARD1
steroidogenic acute regulatory protein Genistein results in increased expression of STAR mRNA increases expression
mRNA 16705744
D019833 6772 STAT1
CANDF7
ISGF-3
STAT91
signal transducer and activator of transcription 1, 91kDa ESR2 promotes the reaction [Genistein results in decreased expression of STAT1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 6772 STAT1
CANDF7
ISGF-3
STAT91
signal transducer and activator of transcription 1, 91kDa Genistein results in decreased expression of STAT1 protein decreases expression
protein 20884965
D019833 6774 STAT3
APRF
HIES
signal transducer and activator of transcription 3 (acute-phase response factor) Genistein inhibits the reaction [Hydrogen Peroxide affects the localization of STAT3 protein] affects localization
/ decreases reaction
protein 10364193
D019833 6774 STAT3
APRF
HIES
signal transducer and activator of transcription 3 (acute-phase response factor) Genistein results in decreased expression of STAT3 mRNA decreases expression
mRNA 20816778
D019833 6781 STC1
STC
stanniocalcin 1 [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of STC1 mRNA affects cotreatment
/ decreases expression
mRNA 16963248
D019833 8614 STC2
STC-2
STCRP
stanniocalcin 2 Genistein results in increased expression of STC2 mRNA increases expression
mRNA 16474171
23019147
D019833 26872 STEAP1
PRSS24
STEAP
six transmembrane epithelial antigen of the prostate 1 Genistein results in decreased expression of STEAP1 mRNA decreases expression
mRNA 16474171
D019833 55240 STEAP3
AHMIO2
STMP3
TSAP6
dudlin-2
STEAP family member 3, metalloreductase Genistein results in increased expression of STEAP3 mRNA increases expression
mRNA 23019147
D019833 27347 STK39
DCHT
PASK
SPAK
serine threonine kinase 39 (EC:2.7.11.1) Genistein results in decreased expression of STK39 mRNA decreases expression
mRNA 15378649
16865672
D019833 3925 STMN1
C1orf215
LAP18
Lag
OP18
PP17
PP19
PR22
SMN
stathmin 1 Genistein results in increased expression of STMN1 mRNA increases expression
mRNA 16474171
D019833 6812 STXBP1
MUNC18-1
NSEC1
P67
RBSEC1
UNC18
syntaxin binding protein 1 Genistein results in increased expression of STXBP1 mRNA increases expression
mRNA 20884965
D019833 55959 SULF2
HSULF-2
sulfatase 2 Genistein results in increased expression of SULF2 mRNA increases expression
mRNA 18847459
D019833 6817 SULT1A1
HAST1/HAST2
P-PST
PST
ST1A1
ST1A3
STP
STP1
TSPST1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) Genistein inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol] decreases reaction
/ increases sulfation
protein 15531517
D019833 6818 SULT1A3
HAST
HAST3
M-PST
ST1A3/ST1A4
ST1A5
STM
TL-PST
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) Genistein inhibits the reaction [SULT1A3 protein results in increased sulfation of Dopamine] decreases reaction
/ increases sulfation
protein 15531517
D019833 6783 SULT1E1
EST
EST-1
ST1E1
STE
sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4) Genistein results in decreased activity of SULT1E1 protein decreases activity
protein 16914110
D019833 6783 SULT1E1
EST
EST-1
ST1E1
STE
sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4) Genistein results in decreased expression of SULT1E1 mRNA decreases expression
mRNA 18634814
D019833 6783 SULT1E1
EST
EST-1
ST1E1
STE
sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4) Genistein results in decreased expression of SULT1E1 protein decreases expression
protein 18634814
D019833 6836 SURF4
ERV29
surfeit 4 Genistein results in decreased expression of SURF4 mRNA decreases expression
mRNA 16705744
D019833 203328 SUSD3
sushi domain containing 3 Genistein results in increased expression of SUSD3 mRNA increases expression
mRNA 20884965
D019833 94056 SYAP1
synapse associated protein 1 ESR1 promotes the reaction [Genistein results in decreased expression of SYAP1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 94056 SYAP1
synapse associated protein 1 Genistein results in decreased expression of SYAP1 protein decreases expression
protein 20884965
D019833 8871 SYNJ2
INPP5H
synaptojanin 2 (EC:3.1.3.36) Genistein results in increased expression of SYNJ2 mRNA increases expression
mRNA 23019147
D019833 10460 TACC3
ERIC-1
ERIC1
transforming, acidic coiled-coil containing protein 3 Genistein results in increased expression of TACC3 mRNA increases expression
mRNA 16474171
D019833 6870 TACR3
HH11
NK-3R
NK3R
NKR
TAC3RL
tachykinin receptor 3 [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of TACR3 mRNA affects cotreatment
/ increases expression
mRNA 16963248
D019833 4070 TACSTD2
EGP-1
EGP1
GA733-1
GA7331
GP50
M1S1
TROP2
tumor-associated calcium signal transducer 2 Genistein results in increased expression of TACSTD2 mRNA increases expression
mRNA 23019147
D019833 22980 TCF25
Hulp1
NULP1
PRO2620
hKIAA1049
transcription factor 25 (basic helix-loop-helix) Genistein results in decreased expression of TCF25 mRNA decreases expression
mRNA 16474171
D019833 6925 TCF4
E2-2
ITF-2
ITF2
PTHS
SEF-2
SEF2
SEF2-1
SEF2-1A
SEF2-1B
TCF-4
bHLHb19
transcription factor 4 Genistein results in decreased expression of TCF4 mRNA decreases expression
mRNA 15256057
D019833 7005 TEAD3
DTEF-1
ETFR-1
TEAD-3
TEAD5
TEF-5
TEF5
TEA domain family member 3 Genistein results in decreased expression of TEAD3 mRNA decreases expression
mRNA 16705744
D019833 9894 TELO2
CLK2
TEL2
telomere maintenance 2 Genistein results in decreased expression of TELO2 mRNA decreases expression
mRNA 16705744
D019833 7015 TERT
CMM9
DKCA2
DKCB4
EST2
PFBMFT1
TCS1
TP2
TRT
hEST2
hTRT
telomerase reverse transcriptase (EC:2.7.7.49) Genistein results in decreased expression of TERT mRNA decreases expression
mRNA 20706672
D019833 7031 TFF1
BCEI
D21S21
HP1.A
HPS2
pNR-2
pS2
trefoil factor 1 ESR1 protein inhibits the reaction [Genistein results in increased expression of TFF1 mRNA] decreases reaction
/ increases expression
mRNA 23384675
D019833 7031 TFF1
BCEI
D21S21
HP1.A
HPS2
pNR-2
pS2
trefoil factor 1 fulvestrant inhibits the reaction [Genistein results in increased expression of TFF1 mRNA] decreases reaction
/ increases expression
mRNA 22562034
D019833 7031 TFF1
BCEI
D21S21
HP1.A
HPS2
pNR-2
pS2
trefoil factor 1 Genistein results in increased expression of TFF1 mRNA increases expression
mRNA 11331657
11368622
15090535
16474171
22562034
23384675
D019833 7033 TFF3
ITF
P1B
TFI
trefoil factor 3 (intestinal) Genistein results in increased expression of TFF3 mRNA increases expression
mRNA 16474171
D019833 7035 TFPI
EPI
LACI
TFI
TFPI1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) Genistein results in decreased expression of TFPI mRNA decreases expression
mRNA 18847459
D019833 7037 TFRC
CD71
T9
TFR
TFR1
TR
TRFR
p90
transferrin receptor ESR2 promotes the reaction [Genistein results in increased expression of TFRC protein] increases expression
/ increases reaction
protein 20884965
D019833 7037 TFRC
CD71
T9
TFR
TFR1
TR
TRFR
p90
transferrin receptor Genistein results in increased expression of TFRC protein increases expression
protein 20884965
D019833 7039 TGFA
TFGA
transforming growth factor, alpha Genistein inhibits the reaction [TGFA protein results in increased expression of PTGS2 mRNA] decreases reaction
/ increases expression
protein 10783318
D019833 7039 TGFA
TFGA
transforming growth factor, alpha Genistein results in increased expression of TGFA mRNA increases expression
mRNA 19371625
23019147
D019833 7040 TGFB1
CED
DPD1
LAP
TGFB
TGFbeta
transforming growth factor, beta 1 Genistein results in decreased expression of TGFB1 mRNA decreases expression
mRNA 20816778
D019833 7042 TGFB2
LDS4
TGF-beta2
transforming growth factor, beta 2 Genistein results in decreased expression of TGFB2 mRNA decreases expression
mRNA 16474171
D019833 7043 TGFB3
ARVD
ARVD1
TGF-beta3
transforming growth factor, beta 3 Genistein results in increased expression of TGFB3 mRNA increases expression
mRNA 11331657
D019833 7057 THBS1
THBS
THBS-1
TSP
TSP-1
TSP1
thrombospondin 1 Genistein results in increased expression of THBS1 mRNA increases expression
mRNA 16474171
19371625
D019833 51337 THEM6
C8orf55
DSCD75
thioesterase superfamily member 6 Genistein results in increased expression of THEM6 mRNA increases expression
mRNA 18847459
D019833 57187 THOC2
CXorf3
THO2
dJ506G2.1
hTREX120
THO complex 2 ESR1 promotes the reaction [Genistein results in decreased expression of THOC2 protein] decreases expression
/ increases reaction
protein 20884965
D019833 57187 THOC2
CXorf3
THO2
dJ506G2.1
hTREX120
THO complex 2 Genistein results in decreased expression of THOC2 protein decreases expression
protein 20884965
D019833 7072 TIA1
TIA-1
WDM
TIA1 cytotoxic granule-associated RNA binding protein Genistein results in increased expression of TIA1 mRNA increases expression
mRNA 15256057
D019833 9220 TIAF1
MAJN
SPR210
TGFB1-induced anti-apoptotic factor 1 Genistein results in increased expression of TIAF1 mRNA increases expression
mRNA 23019147
D019833 26515 TIMM10B
FXC1
TIM10B
Tim9b
translocase of inner mitochondrial membrane 10 homolog B (yeast) ESR1 promotes the reaction [Genistein results in decreased expression of TIMM10B protein] decreases expression
/ increases reaction
protein 20884965
D019833 26515 TIMM10B
FXC1
TIM10B
Tim9b
translocase of inner mitochondrial membrane 10 homolog B (yeast) Genistein results in decreased expression of TIMM10B protein decreases expression
protein 20884965
D019833 7076 TIMP1
CLGI
EPA
EPO
HCI
TIMP
TIMP metallopeptidase inhibitor 1 Genistein inhibits the reaction [Chromium results in increased expression of TIMP1 mRNA] decreases reaction
/ increases expression
mRNA 15878362
D019833 7076 TIMP1
CLGI
EPA
EPO
HCI
TIMP
TIMP metallopeptidase inhibitor 1 Genistein inhibits the reaction [Cobalt results in increased expression of TIMP1 mRNA] decreases reaction
/ increases expression
mRNA 15878362
D019833 7076 TIMP1
CLGI
EPA
EPO
HCI
TIMP
TIMP metallopeptidase inhibitor 1 Genistein inhibits the reaction [Phosphorylcholine analog results in increased expression of TIMP1 mRNA] decreases reaction
/ increases expression
mRNA 15878362
D019833 7076 TIMP1
CLGI
EPA
EPO
HCI
TIMP
TIMP metallopeptidase inhibitor 1 Genistein results in decreased expression of TIMP1 mRNA decreases expression
mRNA 15754008
D019833 7077 TIMP2
CSC-21K
DDC8
TIMP metallopeptidase inhibitor 2 Genistein results in decreased expression of TIMP2 mRNA decreases expression
mRNA 15754008
D019833 7078 TIMP3
HSMRK222
K222
K222TA2
SFD
TIMP metallopeptidase inhibitor 3 Genistein results in decreased expression of TIMP3 mRNA decreases expression
mRNA 15754008
16474171
D019833 26277 TINF2
DKCA3
TIN2
TERF1 (TRF1)-interacting nuclear factor 2 Genistein results in decreased expression of TINF2 mRNA decreases expression
mRNA 19371625
D019833 7083 TK1
TK2
thymidine kinase 1, soluble (EC:2.7.1.21) Genistein results in increased expression of TK1 mRNA increases expression
mRNA 16474171
D019833 7086 TKT
TK
TKT1
transketolase (EC:2.2.1.1) Genistein results in decreased expression of TKT mRNA decreases expression
mRNA 16705744
D019833 7093 TLL2
tolloid-like 2 Genistein results in increased expression of TLL2 mRNA increases expression
mRNA 23019147
D019833 9911 TMCC2
HUCEP11
transmembrane and coiled-coil domain family 2 Genistein results in decreased expression of TMCC2 mRNA decreases expression
mRNA 18444173
D019833 54732 TMED9
GMP25
HSGP25L2G
p25
transmembrane emp24 protein transport domain containing 9 Genistein results in decreased expression of TMED9 mRNA decreases expression
mRNA 16705744
D019833 83862 TMEM120A
NET29
TMPIT
transmembrane protein 120A ESR1 promotes the reaction [Genistein results in increased expression of TMEM120A protein] increases expression
/ increases reaction
protein 20884965
D019833 83862 TMEM120A
NET29
TMPIT
transmembrane protein 120A Genistein results in increased expression of TMEM120A protein increases expression
protein 20884965
D019833 80757 TMEM121
hole
transmembrane protein 121 Genistein results in decreased expression of TMEM121 mRNA decreases expression
mRNA 19371625
D019833 135932 TMEM139
transmembrane protein 139 Genistein results in decreased expression of TMEM139 mRNA decreases expression
mRNA 23019147
D019833 55151 TMEM38B
C9orf87
D4Ertd89e
OI14
TRIC-B
TRICB
bA219P18.1
transmembrane protein 38B Genistein results in increased expression of TMEM38B mRNA increases expression
mRNA 16474171
D019833 55287 TMEM40
transmembrane protein 40 Genistein results in decreased expression of TMEM40 mRNA decreases expression
mRNA 20884965
D019833 120224 TMEM45B
transmembrane protein 45B Genistein results in decreased expression of TMEM45B mRNA decreases expression
mRNA 20884965
D019833 113452 TMEM54
BCLP
CAC-1
CAC1
transmembrane protein 54 Genistein results in decreased expression of TMEM54 mRNA decreases expression
mRNA 19371625
D019833 27346 TMEM97
MAC30
transmembrane protein 97 Genistein results in increased expression of TMEM97 mRNA increases expression
mRNA 16474171
D019833 7112 TMPO
CMD1T
LAP2
LEMD4
PRO0868
TP
thymopoietin Genistein results in increased expression of TMPO mRNA increases expression
mRNA 16474171
D019833 7113 TMPRSS2
PP9284
PRSS10
transmembrane protease, serine 2 (EC:3.4.21.-) Genistein results in decreased expression of TMPRSS2 mRNA decreases expression
mRNA 15378649
D019833 83857 TMTC1
OLF
TMTC1A
transmembrane and tetratricopeptide repeat containing 1 Genistein results in decreased expression of TMTC1 mRNA decreases expression
mRNA 23019147
D019833 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor fulvestrant inhibits the reaction [Genistein inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]] decreases reaction
/ increases expression
protein 12547825
D019833 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA] affects cotreatment
/ decreases reaction
/ increases expression
mRNA 15779068
D019833 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein] affects cotreatment
/ decreases reaction
/ increases expression
protein 15779068
D019833 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Genistein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] decreases reaction
/ increases expression
mRNA 10653605
D019833 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Genistein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] decreases reaction
/ increases expression
protein 10653605
D019833 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Genistein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA] decreases reaction
/ increases expression
mRNA 17934341
D019833 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Genistein inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of TNF protein] decreases reaction
/ increases secretion
protein 17934341
D019833 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Genistein inhibits the reaction [TNF protein results in increased activity of SOD2 protein] decreases reaction
/ increases activity
protein 9372618
D019833 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Genistein inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA] decreases reaction
/ increases expression
protein 9372618
D019833 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Genistein inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] decreases reaction
/ increases expression
protein 12547825
D019833 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Genistein inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein] decreases reaction
/ increases secretion
protein 14534369
D019833 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Genistein promotes the reaction [troglitazone inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein]] decreases reaction
/ increases reaction
/ increases secretion
protein 14534369
D019833 7130 TNFAIP6
TSG-6
TSG6
tumor necrosis factor, alpha-induced protein 6 [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of TNFAIP6 mRNA affects cotreatment
/ decreases expression
mRNA 16963248
D019833 25816 TNFAIP8
GG2-1
MDC-3.13
NDED
SCC-S2
SCCS2
tumor necrosis factor, alpha-induced protein 8 Genistein results in decreased expression of TNFAIP8 mRNA decreases expression
mRNA 15378649
D019833 8795 TNFRSF10B
CD262
DR5
KILLER
KILLER/DR5
TRAIL-R2
TRAILR2
TRICK2
TRICK2A
TRICK2B
TRICKB
ZTNFR9
tumor necrosis factor receptor superfamily, member 10b Genistein results in decreased expression of TNFRSF10B mRNA decreases expression
mRNA 16705744
D019833 4982 TNFRSF11B
OCIF
OPG
TR1
tumor necrosis factor receptor superfamily, member 11b Genistein results in increased expression of TNFRSF11B mRNA increases expression
mRNA 15256057
D019833 51330 TNFRSF12A
CD266
FN14
TWEAKR
tumor necrosis factor receptor superfamily, member 12A Genistein results in decreased expression of TNFRSF12A mRNA decreases expression
mRNA 16705744
D019833 7132 TNFRSF1A
CD120a
FPF
MS5
TBP1
TNF-R
TNF-R-I
TNF-R55
TNFAR
TNFR1
TNFR1-d2
TNFR55
TNFR60
p55
p55-R
p60
tumor necrosis factor receptor superfamily, member 1A [Genistein co-treated with trichostatin A] results in increased expression of TNFRSF1A mRNA affects cotreatment
/ increases expression
mRNA 22626855
D019833 7132 TNFRSF1A
CD120a
FPF
MS5
TBP1
TNF-R
TNF-R-I
TNF-R55
TNFAR
TNFR1
TNFR1-d2
TNFR55
TNFR60
p55
p55-R
p60
tumor necrosis factor receptor superfamily, member 1A [Genistein co-treated with trichostatin A] results in increased expression of TNFRSF1A protein affects cotreatment
/ increases expression
protein 22626855
D019833 8718 TNFRSF25
APO-3
DDR3
DR3
LARD
TNFRSF12
TR3
TRAMP
WSL-1
WSL-LR
tumor necrosis factor receptor superfamily, member 25 Genistein results in decreased expression of TNFRSF25 mRNA decreases expression
mRNA 19371625
D019833 8718 TNFRSF25
APO-3
DDR3
DR3
LARD
TNFRSF12
TR3
TRAMP
WSL-1
WSL-LR
tumor necrosis factor receptor superfamily, member 25 Genistein results in increased expression of TNFRSF25 mRNA increases expression
mRNA 23019147
D019833 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone results in decreased susceptibility to [Genistein co-treated with TNFSF10 protein] affects cotreatment
/ decreases response to substance
protein 19497411
D019833 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone analog results in decreased susceptibility to [Genistein co-treated with TNFSF10 protein] affects cotreatment
/ decreases response to substance
protein 19497411
D019833 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone results in decreased susceptibility to [Genistein co-treated with TNFSF10 protein] affects cotreatment
/ decreases response to substance
protein 19497411
D019833 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 benzyloxycarbonyl-valyl-alanyl-aspartic acid analog results in decreased susceptibility to [Genistein co-treated with TNFSF10 protein] affects cotreatment
/ decreases response to substance
protein 19497411
D019833 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 [Genistein co-treated with TNFSF10 protein] results in decreased expression of BCL2 protein affects cotreatment
/ decreases expression
protein 19497411
D019833 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 [Genistein co-treated with TNFSF10 protein] results in decreased expression of XIAP protein affects cotreatment
/ decreases expression
protein 19497411
D019833 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 [Genistein co-treated with TNFSF10 protein] results in increased activity of CASP3 protein affects cotreatment
/ increases activity
protein 19497411
D019833 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 [Genistein co-treated with TNFSF10 protein] results in increased activity of CASP8 protein affects cotreatment
/ increases activity
protein 19497411
D019833 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 [Genistein co-treated with TNFSF10 protein] results in increased activity of CASP9 protein affects cotreatment
/ increases activity
protein 19497411
D019833 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 [Genistein co-treated with TNFSF10 protein] results in increased cleavage of BID protein affects cotreatment
/ increases cleavage
protein 19497411
D019833 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 [Genistein co-treated with TNFSF10 protein] results in increased expression of BAX protein affects cotreatment
/ increases expression
protein 19497411
D019833 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 Genistein results in increased susceptibility to TNFSF10 protein increases response to substance
protein 19497411
D019833 7292 TNFSF4
CD134L
CD252
GP34
OX-40L
OX4OL
TXGP1
tumor necrosis factor (ligand) superfamily, member 4 Genistein results in decreased expression of TNFSF4 mRNA decreases expression
mRNA 18444173
D019833 8744 TNFSF9
4-1BB-L
CD137L
tumor necrosis factor (ligand) superfamily, member 9 Genistein results in increased expression of TNFSF9 mRNA increases expression
mRNA 18847459
D019833 85456 TNKS1BP1
TAB182
tankyrase 1 binding protein 1, 182kDa ESR2 promotes the reaction [Genistein results in decreased expression of TNKS1BP1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 85456 TNKS1BP1
TAB182
tankyrase 1 binding protein 1, 182kDa Genistein results in decreased expression of TNKS1BP1 protein decreases expression
protein 20884965
D019833 7138 TNNT1
ANM
NEM5
STNT
TNT
TNTS
troponin T type 1 (skeletal, slow) Genistein results in decreased expression of TNNT1 mRNA decreases expression
mRNA 19371625
D019833 10452 TOMM40
C19orf1
D19S1177E
PER-EC1
PEREC1
TOM40
translocase of outer mitochondrial membrane 40 homolog (yeast) ESR1 promotes the reaction [Genistein results in decreased expression of TOMM40 protein] decreases expression
/ increases reaction
protein 20884965
D019833 10452 TOMM40
C19orf1
D19S1177E
PER-EC1
PEREC1
TOM40
translocase of outer mitochondrial membrane 40 homolog (yeast) Genistein results in decreased expression of TOMM40 protein decreases expression
protein 20884965
D019833 7153 TOP2A
TOP2
TP2A
topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) Genistein results in increased expression of TOP2A mRNA increases expression
mRNA 16474171
D019833 7155 TOP2B
TOPIIB
top2beta
topoisomerase (DNA) II beta 180kDa (EC:5.99.1.3) ESR2 promotes the reaction [Genistein results in decreased expression of TOP2B protein] decreases expression
/ increases reaction
protein 20884965
D019833 7155 TOP2B
TOPIIB
top2beta
topoisomerase (DNA) II beta 180kDa (EC:5.99.1.3) Genistein results in decreased expression of TOP2B protein decreases expression
protein 20884965
D019833 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 [Fluorouracil co-treated with Genistein] results in increased expression of TP53 mRNA affects cotreatment
/ increases expression
mRNA 15896711
D019833 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Genistein affects the expression of TP53 mRNA affects expression
mRNA 18431742
D019833 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Genistein affects the expression of TP53 protein affects expression
protein 18431742
D019833 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 [Genistein co-treated with trichostatin A] results in increased expression of TP53 protein affects cotreatment
/ increases expression
protein 22626855
D019833 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Genistein inhibits the reaction [HIST3H3 protein modified form binds to TP53 promoter] affects binding
/ decreases reaction
promoter 18431742
D019833 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Genistein inhibits the reaction [SIRT1 protein binds to TP53 promoter] affects binding
/ decreases reaction
promoter 18431742
D019833 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Genistein promotes the reaction [Fluorouracil results in increased expression of TP53 protein] increases expression
/ increases reaction
protein 15896711
D019833 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 [[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased expression of TP53 protein decreases activity
/ increases expression
protein 18431742
D019833 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Genistein results in increased expression of TP53 protein increases expression
protein 19800779
D019833 9537 TP53I11
PIG11
tumor protein p53 inducible protein 11 Genistein results in decreased expression of TP53I11 mRNA decreases expression
mRNA 15757668
D019833 9540 TP53I3
PIG3
tumor protein p53 inducible protein 3 ESR2 promotes the reaction [Genistein results in increased expression of TP53I3 protein] increases expression
/ increases reaction
protein 20884965
D019833 9540 TP53I3
PIG3
tumor protein p53 inducible protein 3 Genistein results in increased expression of TP53I3 protein increases expression
protein 20884965
D019833 94241 TP53INP1
SIP
TP53DINP1
TP53INP1A
TP53INP1B
Teap
p53DINP1
tumor protein p53 inducible nuclear protein 1 Genistein results in decreased expression of TP53INP1 mRNA decreases expression
mRNA 23019147
D019833 94241 TP53INP1
SIP
TP53DINP1
TP53INP1A
TP53INP1B
Teap
p53DINP1
tumor protein p53 inducible nuclear protein 1 Genistein results in increased expression of TP53INP1 mRNA increases expression
mRNA 18847459
D019833 8626 TP63
AIS
B(p51A)
B(p51B)
EEC3
KET
LMS
NBP
OFC8
RHS
SHFM4
TP53CP
TP53L
TP73L
p40
p51
p53CP
p63
p73H
p73L
tumor protein p63 Genistein results in increased expression of TP63 mRNA increases expression
mRNA 15256057
D019833 7164 TPD52L1
D53
hD53
tumor protein D52-like 1 Genistein results in increased expression of TPD52L1 mRNA increases expression
mRNA 15757668
D019833 27010 TPK1
HTPK1
PP20
THMD5
thiamin pyrophosphokinase 1 (EC:2.7.6.2) Genistein results in decreased expression of TPK1 mRNA decreases expression
mRNA 23019147
D019833 7168 TPM1
C15orf13
CMD1Y
CMH3
HTM-alpha
LVNC9
TMSA
tropomyosin 1 (alpha) Genistein results in decreased expression of TPM1 mRNA decreases expression
mRNA 20884965
D019833 7170 TPM3
CAPM1
CFTD
NEM1
OK/SW-cl.5
TM-5
TM3
TM30
TM30nm
TM5
TPMsk3
TRK
hscp30
tropomyosin 3 Genistein results in increased expression of TPM3 mRNA increases expression
mRNA 16474171
D019833 7173 TPO
MSA
TDH2A
TPX
thyroid peroxidase (EC:1.11.1.8) Genistein results in decreased activity of TPO protein decreases activity
protein 21809831
D019833 7175 TPR
translocated promoter region, nuclear basket protein ESR1 promotes the reaction [Genistein results in decreased expression of TPR protein] decreases expression
/ increases reaction
protein 20884965
D019833 7175 TPR
translocated promoter region, nuclear basket protein Genistein results in decreased expression of TPR protein decreases expression
protein 20884965
D019833 10626 TRIM16
EBBP
tripartite motif containing 16 Genistein results in decreased expression of TRIM16 mRNA decreases expression
mRNA 16474171
D019833 7706 TRIM25
EFP
RNF147
Z147
ZNF147
tripartite motif containing 25 (EC:6.3.2.19 6.3.2.n3) Genistein results in increased expression of TRIM25 mRNA increases expression
mRNA 23019147
D019833 129868 TRIM43
TRIM43A
tripartite motif containing 43 Genistein results in decreased expression of TRIM43 mRNA decreases expression
mRNA 23019147
D019833 653192 TRIM43B
tripartite motif containing 43B Genistein results in decreased expression of TRIM43B mRNA decreases expression
mRNA 23019147
D019833 9319 TRIP13
16E1BP
thyroid hormone receptor interactor 13 Genistein results in increased expression of TRIP13 mRNA increases expression
mRNA 16474171
D019833 51504 TRMT112
HSPC152
HSPC170
TRM112
TRMT11-2
tRNA methyltransferase 11-2 homolog (S. cerevisiae) ESR2 promotes the reaction [Genistein results in increased expression of TRMT112 protein] increases expression
/ increases reaction
protein 20884965
D019833 51504 TRMT112
HSPC152
HSPC170
TRM112
TRMT11-2
tRNA methyltransferase 11-2 homolog (S. cerevisiae) Genistein results in increased expression of TRMT112 protein increases expression
protein 20884965
D019833 8848 TSC22D1
Ptg-2
TGFB1I4
TSC22
TSC22 domain family, member 1 Genistein results in decreased expression of TSC22D1 mRNA decreases expression
mRNA 19371625
D019833 8848 TSC22D1
Ptg-2
TGFB1I4
TSC22
TSC22 domain family, member 1 Genistein results in increased expression of TSC22D1 mRNA increases expression
mRNA 18847459
D019833 25987 TSKU
E2IG4
LRRC54
TSK
tsukushi, small leucine rich proteoglycan Genistein results in increased expression of TSKU mRNA increases expression
mRNA 19371625
23019147
D019833 23554 TSPAN12
EVR5
NET-2
NET2
TM4SF12
tetraspanin 12 Genistein results in decreased expression of TSPAN12 mRNA decreases expression
mRNA 19371625
D019833 146057 TTBK2
SCA11
TTBK
tau tubulin kinase 2 (EC:2.7.11.1) ESR1 promotes the reaction [Genistein results in increased expression of TTBK2 protein] increases expression
/ increases reaction
protein 20884965
D019833 146057 TTBK2
SCA11
TTBK
tau tubulin kinase 2 (EC:2.7.11.1) Genistein results in increased expression of TTBK2 protein increases expression
protein 20884965
D019833 283237 TTC9C
tetratricopeptide repeat domain 9C ESR2 promotes the reaction [Genistein results in decreased expression of TTC9C protein] decreases expression
/ increases reaction
protein 20884965
D019833 283237 TTC9C
tetratricopeptide repeat domain 9C Genistein results in decreased expression of TTC9C protein decreases expression
protein 20884965
D019833 7272 TTK
CT96
ESK
MPH1
MPS1
MPS1L1
PYT
TTK protein kinase (EC:2.7.12.1) Genistein affects the expression of TTK mRNA affects expression
mRNA 18847459
D019833 23170 TTLL12
dJ526I14.2
tubulin tyrosine ligase-like family, member 12 Genistein results in increased expression of TTLL12 mRNA increases expression
mRNA 23019147
D019833 7277 TUBA4A
H2-ALPHA
TUBA1
tubulin, alpha 4a Genistein results in decreased expression of TUBA4A mRNA decreases expression
mRNA 20884965
D019833 203068 TUBB
M40
OK/SW-cl.56
TUBB1
TUBB5
tubulin, beta class I Genistein results in decreased expression of TUBB mRNA decreases expression
mRNA 16705744
D019833 84617 TUBB6
HsT1601
TUBB-5
tubulin, beta 6 class V Genistein results in increased expression of TUBB6 mRNA increases expression
mRNA 16474171
D019833 7289 TULP3
TUBL3
tubby like protein 3 Genistein results in decreased expression of TULP3 mRNA decreases expression
mRNA 16705744
D019833 200081 TXLNA
IL14
RP4-622L5.4
TXLN
taxilin alpha Genistein results in decreased expression of TXLNA mRNA decreases expression
mRNA 16705744
D019833 7295 TXN
TRDX
TRX
TRX1
thioredoxin Genistein results in decreased expression of TXN mRNA decreases expression
mRNA 20706672
D019833 7296 TXNRD1
GRIM-12
TR
TR1
TRXR1
TXNR
thioredoxin reductase 1 (EC:1.8.1.9) Genistein results in increased expression of TXNRD1 mRNA increases expression
mRNA 18444173
D019833 7298 TYMS
HST422
TMS
TS
thymidylate synthetase (EC:2.1.1.45) Genistein results in increased expression of TYMS mRNA increases expression
mRNA 16474171
D019833 7306 TYRP1
CAS2
CATB
GP75
OCA3
TRP
TRP1
TYRP
b-PROTEIN
tyrosinase-related protein 1 (EC:1.14.18.-) Genistein results in decreased expression of TYRP1 mRNA decreases expression
mRNA 20706672
D019833 6675 UAP1
AGX
AGX1
AGX2
SPAG2
UDP-N-acetylglucosamine pyrophosphorylase 1 (EC:2.7.7.23 2.7.7.83) Genistein results in decreased expression of UAP1 mRNA decreases expression
mRNA 15378649
D019833 9898 UBAP2L
NICE-4
ubiquitin associated protein 2-like Genistein results in decreased expression of UBAP2L mRNA decreases expression
mRNA 16705744
D019833 11065 UBE2C
UBCH10
dJ447F3.2
ubiquitin-conjugating enzyme E2C (EC:6.3.2.19) Genistein affects the expression of UBE2C mRNA alternative form affects expression
mRNA 18847459
D019833 11065 UBE2C
UBCH10
dJ447F3.2
ubiquitin-conjugating enzyme E2C (EC:6.3.2.19) Genistein results in increased expression of UBE2C mRNA increases expression
mRNA 16474171
D019833 9246 UBE2L6
RIG-B
UBCH8
ubiquitin-conjugating enzyme E2L 6 (EC:6.3.2.19) ESR2 promotes the reaction [Genistein results in decreased expression of UBE2L6 protein] decreases expression
/ increases reaction
protein 20884965
D019833 9246 UBE2L6
RIG-B
UBCH8
ubiquitin-conjugating enzyme E2L 6 (EC:6.3.2.19) Genistein results in decreased expression of UBE2L6 protein decreases expression
protein 20884965
D019833 29089 UBE2T
PIG50
ubiquitin-conjugating enzyme E2T (putative) (EC:6.3.2.19) Genistein results in increased expression of UBE2T mRNA increases expression
mRNA 16474171
D019833 56893 UBQLN4
A1U
A1Up
C1orf6
CIP75
UBIN
ubiquilin 4 Genistein results in increased expression of UBQLN4 mRNA increases expression
mRNA 23019147
D019833 7343 UBTF
NOR-90
UBF
UBF-1
UBF1
upstream binding transcription factor, RNA polymerase I ESR2 promotes the reaction [Genistein results in decreased expression of UBTF protein] decreases expression
/ increases reaction
protein 20884965
D019833 7343 UBTF
NOR-90
UBF
UBF-1
UBF1
upstream binding transcription factor, RNA polymerase I Genistein results in decreased expression of UBTF protein decreases expression
protein 20884965
D019833 7345 UCHL1
NDGOA
PARK5
PGP_9.5
PGP9.5
PGP95
Uch-L1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (EC:3.4.19.12) [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of UCHL1 mRNA affects cotreatment
/ decreases expression
mRNA 16963248
D019833 7358 UGDH
GDH
UDP-GlcDH
UDPGDH
UGD
UDP-glucose 6-dehydrogenase (EC:1.1.1.22) ESR2 promotes the reaction [Genistein results in decreased expression of UGDH protein] decreases expression
/ increases reaction
protein 20884965
D019833 7358 UGDH
GDH
UDP-GlcDH
UDPGDH
UGD
UDP-glucose 6-dehydrogenase (EC:1.1.1.22) Genistein results in decreased expression of UGDH protein decreases expression
protein 20884965
D019833 7358 UGDH
GDH
UDP-GlcDH
UDPGDH
UGD
UDP-glucose 6-dehydrogenase (EC:1.1.1.22) Genistein results in increased expression of UGDH mRNA increases expression
mRNA 15378649
16865672
D019833 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) Genistein results in decreased activity of UGT1A1 protein decreases activity
protein 16051636
D019833 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) Genistein results in decreased expression of UGT1A1 mRNA decreases expression
mRNA 18634814
D019833 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) Genistein results in decreased expression of UGT1A1 protein decreases expression
protein 18634814
D019833 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) UGT1A1 protein results in increased glucuronidation of Genistein increases glucuronidation
protein 14557274
15988124
D019833 54575 UGT1A10
UDPGT
UGT-1J
UGT1-10
UGT1.10
UGT1J
UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) UGT1A10 protein results in increased glucuronidation of Genistein increases glucuronidation
protein 14557274
D019833 54659 UGT1A3
UDPGT
UDPGT_1-3
UGT-1C
UGT1-03
UGT1.3
UGT1C
UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) Genistein results in decreased expression of UGT1A3 mRNA decreases expression
mRNA 16474171
D019833 54659 UGT1A3
UDPGT
UDPGT_1-3
UGT-1C
UGT1-03
UGT1.3
UGT1C
UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) UGT1A3 protein results in increased glucuronidation of Genistein increases glucuronidation
protein 15988124
D019833 54577 UGT1A7
UDPGT
UDPGT_1-7
UGT-1G
UGT1-07
UGT1.7
UGT1G
UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) UGT1A7 protein results in increased glucuronidation of Genistein increases glucuronidation
protein 14557274
D019833 54576 UGT1A8
UDPGT
UDPGT_1-8
UGT-1H
UGT1-08
UGT1.8
UGT1A8S
UGT1H
UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) UGT1A8 protein results in increased glucuronidation of Genistein increases glucuronidation
protein 14557274
D019833 54600 UGT1A9
HLUGP4
LUGP4
UDPGT
UDPGT_1-9
UGT-1I
UGT1-09
UGT1-9
UGT1.9
UGT1AI
UGT1I
UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) UGT1A9 protein results in increased glucuronidation of Genistein increases glucuronidation
protein 14557274
15988124
D019833 7366 UGT2B15
HLUG4
UDPGT_2B8
UDPGT2B15
UDPGTH3
UGT2B8
UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) Genistein results in increased expression of UGT2B15 mRNA increases expression
mRNA 16690804
16865672
23524099
D019833 7367 UGT2B17
BMND12
UDPGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17 (EC:2.4.1.17) Genistein results in increased expression of UGT2B17 mRNA increases expression
mRNA 16865672
D019833 29128 UHRF1
ICBP90
Np95
RNF106
hNP95
hUHRF1
ubiquitin-like with PHD and ring finger domains 1 (EC:6.3.2.19) Genistein results in increased expression of UHRF1 mRNA increases expression
mRNA 16474171
D019833 7374 UNG
DGU
HIGM4
HIGM5
UDG
UNG1
UNG15
UNG2
uracil-DNA glycosylase (EC:3.2.2.27) Genistein results in increased expression of UNG mRNA increases expression
mRNA 16474171
D019833 10868 USP20
LSFR3A
VDU2
hVDU2
ubiquitin specific peptidase 20 (EC:3.4.19.12) Genistein results in decreased expression of USP20 mRNA decreases expression
mRNA 16705744
D019833 114990 VASN
SLITL2
vasorin Genistein results in increased expression of VASN mRNA increases expression
mRNA 23019147
D019833 10493 VAT1
VATI
vesicle amine transport 1 ESR1 promotes the reaction [Genistein results in decreased expression of VAT1 protein] decreases expression
/ increases reaction
protein 20884965
D019833 10493 VAT1
VATI
vesicle amine transport 1 Genistein results in decreased expression of VAT1 protein decreases expression
protein 20884965
D019833 7409 VAV1
VAV
vav 1 guanine nucleotide exchange factor Genistein inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of VAV1 protein] decreases reaction
/ increases phosphorylation
protein 20561557
D019833 7412 VCAM1
CD106
INCAM-100
vascular cell adhesion molecule 1 ESR2 gene polymorphism affects the reaction [[Genistein co-treated with daidzein] affects the expression of VCAM1 protein] affects cotreatment
/ affects expression
/ affects reaction
protein 16332659
D019833 7412 VCAM1
CD106
INCAM-100
vascular cell adhesion molecule 1 fulvestrant inhibits the reaction [Genistein inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]] decreases reaction
/ increases expression
mRNA 12547825
D019833 7412 VCAM1
CD106
INCAM-100
vascular cell adhesion molecule 1 Genistein inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] decreases reaction
/ increases expression
mRNA 12547825
D019833 7414 VCL
CMD1W
CMH15
MV
MVCL
vinculin ESR2 promotes the reaction [Genistein results in decreased expression of VCL protein] decreases expression
/ increases reaction
protein 20884965
D019833 7414 VCL
CMD1W
CMH15
MV
MVCL
vinculin Genistein results in decreased expression of VCL protein decreases expression
protein 20884965
D019833 79609 VCPKMT
C14orf138
METTL21D
VCP-KMT
valosin containing protein lysine (K) methyltransferase Genistein results in decreased expression of VCPKMT mRNA decreases expression
mRNA 19371625
D019833 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor fulvestrant inhibits the reaction [Genistein results in increased expression of VDR protein] decreases reaction
/ increases expression
protein 17088408
D019833 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor Genistein promotes the reaction [Calcitriol results in increased expression of VDR mRNA] increases expression
/ increases reaction
mRNA 15955619
D019833 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor Genistein promotes the reaction [Calcitriol results in increased expression of VDR protein] increases expression
/ increases reaction
protein 15955619
D019833 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor Genistein promotes the reaction [SP1 protein binds to VDR promoter] affects binding
/ increases reaction
promoter 17088408
D019833 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor Genistein results in increased expression of VDR mRNA increases expression
mRNA 12710998
17088408
D019833 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor Genistein results in increased expression of VDR protein increases expression
protein 12710998
17088408
D019833 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor Tamoxifen inhibits the reaction [Genistein results in increased expression of VDR mRNA] decreases reaction
/ increases expression
mRNA 12710998
D019833 7421 VDR
NR1I1
vitamin D (1,25- dihydroxyvitamin D3) receptor U 0126 inhibits the reaction [Genistein results in increased expression of VDR protein] decreases reaction
/ increases expression
protein 17088408
D019833 7422 VEGFA
MVCD1
VEGF
VPF
vascular endothelial growth factor A 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased secretion of VEGFA protein] decreases reaction
/ increases secretion
protein 18252963
D019833 7422 VEGFA
MVCD1
VEGF
VPF
vascular endothelial growth factor A 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased secretion of VEGFA protein] decreases reaction
/ increases secretion
protein 18252963
D019833 7422 VEGFA
MVCD1
VEGF
VPF
vascular endothelial growth factor A fulvestrant inhibits the reaction [Genistein results in increased secretion of VEGFA protein] decreases reaction
/ increases secretion
protein 18252963
D019833 7422 VEGFA
MVCD1
VEGF
VPF
vascular endothelial growth factor A [Genistein co-treated with arsenic trioxide] results in decreased expression of VEGFA protein affects cotreatment
/ decreases expression
protein 21078540
D019833 7422 VEGFA
MVCD1
VEGF
VPF
vascular endothelial growth factor A Genistein results in decreased expression of VEGFA mRNA decreases expression
mRNA 19005980
D019833 7422 VEGFA
MVCD1
VEGF
VPF
vascular endothelial growth factor A Genistein results in decreased expression of VEGFA protein decreases expression
protein 19005980
21078540
D019833 7422 VEGFA
MVCD1
VEGF
VPF
vascular endothelial growth factor A Genistein results in increased secretion of VEGFA protein increases secretion
protein 18252963
D019833 7422 VEGFA
MVCD1
VEGF
VPF
vascular endothelial growth factor A SB 203580 inhibits the reaction [Genistein results in increased secretion of VEGFA protein] decreases reaction
/ increases secretion
protein 18252963
D019833 7422 VEGFA
MVCD1
VEGF
VPF
vascular endothelial growth factor A wortmannin inhibits the reaction [Genistein results in increased secretion of VEGFA protein] decreases reaction
/ increases secretion
protein 18252963
D019833 40542 ESR2 promotes the reaction [Genistein results in increased expression of VPS24 protein] increases expression
/ increases reaction
protein 20884965
D019833 40542 Genistein results in increased expression of VPS24 protein increases expression
protein 20884965
D019833 7453 WARS
GAMMA-2
IFI53
IFP53
tryptophanyl-tRNA synthetase (EC:6.1.1.2) Genistein results in increased expression of WARS mRNA increases expression
mRNA 15159206
15757668
D019833 10885 WDR3
DIP2
UTP12
WD repeat domain 3 Genistein results in increased expression of WDR3 mRNA increases expression
mRNA 23019147
D019833 10785 WDR4
TRM82
TRMT82
WD repeat domain 4 Genistein results in decreased expression of WDR4 mRNA decreases expression
mRNA 18847459
D019833 8839 WISP2
CCN5
CT58
CTGF-L
WNT1 inducible signaling pathway protein 2 ESR1 protein inhibits the reaction [Genistein results in increased expression of WISP2 mRNA] decreases reaction
/ increases expression
mRNA 23384675
D019833 8839 WISP2
CCN5
CT58
CTGF-L
WNT1 inducible signaling pathway protein 2 Genistein results in increased expression of WISP2 mRNA increases expression
mRNA 23384675
D019833 7476 WNT7A
wingless-type MMTV integration site family, member 7A Genistein results in decreased expression of WNT7A mRNA decreases expression
mRNA 16534752
D019833 331 XIAP
API3
BIRC4
IAP-3
ILP1
MIHA
XLP2
hIAP-3
hIAP3
X-linked inhibitor of apoptosis [Genistein co-treated with TNFSF10 protein] results in decreased expression of XIAP protein affects cotreatment
/ decreases expression
protein 19497411
D019833 331 XIAP
API3
BIRC4
IAP-3
ILP1
MIHA
XLP2
hIAP-3
hIAP3
X-linked inhibitor of apoptosis Genistein promotes the reaction [arsenic trioxide results in decreased expression of XIAP protein] decreases expression
/ increases reaction
protein 18546268
D019833 331 XIAP
API3
BIRC4
IAP-3
ILP1
MIHA
XLP2
hIAP-3
hIAP3
X-linked inhibitor of apoptosis Genistein results in decreased expression of XIAP protein decreases expression
protein 18546268
D019833 51646 YPEL5
yippee-like 5 (Drosophila) Genistein results in decreased expression of YPEL5 mRNA decreases expression
mRNA 16474171
23019147
D019833 79413 ZBED2
zinc finger, BED-type containing 2 Genistein results in decreased expression of ZBED2 mRNA decreases expression
mRNA 23019147
D019833 84872 ZC3H10
ZC3HDC10
zinc finger CCCH-type containing 10 Genistein results in increased expression of ZC3H10 mRNA increases expression
mRNA 18847459
D019833 677 ZFP36L1
BRF1
Berg36
ERF-1
ERF1
RNF162B
TIS11B
cMG1
ZFP36 ring finger protein-like 1 Genistein results in decreased expression of ZFP36L1 mRNA decreases expression
mRNA 16474171
D019833 23414 ZFPM2
DIH3
FOG2
ZC2HC11B
ZNF89B
hFOG-2
zinc finger protein, FOG family member 2 Genistein results in decreased expression of ZFPM2 mRNA decreases expression
mRNA 15256057
D019833 342357 ZKSCAN2
ZNF694
ZSCAN31
ZSCAN34
zinc finger with KRAB and SCAN domains 2 Genistein results in increased expression of ZKSCAN2 mRNA increases expression
mRNA 19371625
D019833 9203 ZMYM3
DXS6673E
MYM
XFIM
ZNF198L2
ZNF261
zinc finger, MYM-type 3 Genistein results in increased expression of ZMYM3 mRNA increases expression
mRNA 19371625
D019833 7730 ZNF177
PIGX
zinc finger protein 177 Genistein results in increased expression of ZNF177 mRNA increases expression
mRNA 15256057
D019833 7587 ZNF37A
KOX21
ZNF37
zinc finger protein 37A Genistein results in decreased expression of ZNF37A mRNA decreases expression
mRNA 18444173
D019833 80139 ZNF703
ZEPPO1
ZNF503L
ZPO1
zinc finger protein 703 Genistein results in increased expression of ZNF703 mRNA increases expression
mRNA 16474171
D019833 11130 ZWINT
HZwint-1
KNTC2AP
ZWINT1
ZW10 interacting kinetochore protein Genistein results in increased expression of ZWINT mRNA increases expression
mRNA 16474171

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (117)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103780 Alcohol dependence P08172
P14416
P31645
#610251 Alcohol sensitivity, acute P05091
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#614490 Blood group, junior system; jr Q9UNQ0
#210900 Bloom syndrome; blm P54132
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
%606641 Body mass index; bmi P37231
#114480 Breast cancer P31749
P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#300615 Brunner syndrome P21397
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#118300 Charcot-marie-tooth disease and deafness Q01453
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#114500 Colorectal cancer; crc P31749
#615109 Cowden syndrome 6; cws6 P31749
#162800 Cyclic neutropenia P08246
#608565 Deafness, autosomal recessive 35; dfnb35 O95718
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#237500 Dubin-johnson syndrome; djs Q92887
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#137800 Glioma susceptibility 1; glm1 P04626
P37231
#139393 Guillain-barre syndrome, familial; gbs Q01453
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237450 Hyperbilirubinemia, rotor type; hblrr Q9NPD5
Q9Y6L6
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#612244 Inflammatory bowel disease 13; ibd13 P08183
#603932 Intervertebral disc disease; idd P14780
#608232 Leukemia, chronic myeloid; cml P00519
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P04637
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#609048 Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 P11802
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#254500 Myeloma, multiple P24385
#159900 Myoclonic dystonia P14416
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#257220 Niemann-pick disease, type c1; npc1 O15118
#601665 Obesity P32245
P37231
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#172700 Pick disease of brain P10636
#176920 Proteus syndrome P31749
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#187950 Thrombocythemia 1; thcyt1 P40225
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#610379 West nile virus, susceptibility to P51681
#278300 Xanthinuria, type i P47989
#112100 Yt blood group antigen P22303

KEGG DISEASE (106)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00605 Deafness, autosomal recessive O95718 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) P00519 (related)
P00519 (marker)
Q03164 (related)
Q03164 (marker)
H00004 Chronic myeloid leukemia (CML) P00519 (related)
P00519 (marker)
P04637 (related)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P24385 (related)
P24385 (marker)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P24385 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P04637 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
P04637 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P04637 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
P11802 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P11802 (related)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P24385 (related)
P24385 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q01453 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
P04637 (related)
Q92731 (marker)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
P11511 (related)
H00019 Pancreatic cancer P04626 (related)
P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04626 (related)
P04637 (related)
P38398 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P04637 (related)
P24385 (related)
P38398 (related)
H00046 Cholangiocarcinoma P04626 (related)
P04637 (related)
P35354 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
P24385 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
P24385 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P14780 (related)
P35354 (related)
H00029 Vulvar cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P37231 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P11802 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00044 Cancer of the anal canal P04637 (related)
H00047 Gallbladder cancer P04637 (related)
P24385 (marker)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H01071 Acute alcohol sensitivity P05091 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00794 Aromatase excess syndrome P11511 (related)
H01205 Coumarin resistance P11712 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00548 Brunner syndrome P21397 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00559 von Hippel-Lindau syndrome P24385 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00227 Congenital amegakaryocytic thrombocytopenia (CAMT) P40225 (marker)
H00192 Xanthinuria P47989 (related)
Q06278 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)
H00208 Hyperbilirubinemia Q92887 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)

Diseases related to CTD interactions

38 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D000014 D019833 Abnormalities, Drug-Induced marker/mechanism
20299547
D000022 D019833 Abortion, Spontaneous marker/mechanism
21810550
D000230 D019833 Adenocarcinoma marker/mechanism
therapeutic
11389053
11473722
C538231 D019833 Adenocarcinoma of lung therapeutic
22626855
D001836 D019833 Body Weight Changes marker/mechanism
14580783
D001943 D019833 Breast Neoplasms marker/mechanism
therapeutic
16541309
16873071
17200150
D006528 D019833 Carcinoma, Hepatocellular therapeutic
16924424
21078540
D002318 D019833 Cardiovascular Diseases therapeutic
16332659
D003110 D019833 Colonic Neoplasms therapeutic
17182828
D000013 D019833 Congenital Abnormalities therapeutic
22736253
D003924 D019833 Diabetes Mellitus, Type 2 therapeutic
16647724
D012734 D019833 Disorders of Sex Development marker/mechanism
19672408
D004487 D019833 Edema therapeutic
22981962
D004714 D019833 Endometrial Hyperplasia therapeutic
16402032
D016889 D019833 Endometrial Neoplasms therapeutic
11473722
D005909 D019833 Glioblastoma therapeutic
16598420
D006402 D019833 Hematologic Diseases marker/mechanism
21048042
D006965 D019833 Hyperplasia therapeutic
22981962
D007938 D019833 Leukemia marker/mechanism
therapeutic
17468513
18980019
D017254 D019833 Leukemic Infiltration therapeutic
22981962
D008104 D019833 Liver Cirrhosis, Alcoholic therapeutic
23274713
D008106 D019833 Liver Cirrhosis, Experimental therapeutic
17823541
D008325 D019833 Mammary Neoplasms, Experimental marker/mechanism
therapeutic
12929590
14578162
D008679 D019833 Metaplasia marker/mechanism
11389053
D009203 D019833 Myocardial Infarction therapeutic
17141266
D015428 D019833 Myocardial Reperfusion Injury therapeutic
17141266
D009336 D019833 Necrosis marker/mechanism
10572627
D009369 D019833 Neoplasms marker/mechanism
therapeutic
20219070
21177254
D009421 D019833 Nervous System Malformations marker/mechanism
16427766
20299547
D009845 D019833 Oligospermia marker/mechanism
19672408
D010024 D019833 Osteoporosis therapeutic
19401787
D015663 D019833 OSTEOPOROSIS, POSTMENOPAUSAL therapeutic
16169203
D010051 D019833 Ovarian Neoplasms therapeutic
19005980
D047928 D019833 Premature Birth marker/mechanism
21816468
D011297 D019833 Prenatal Exposure Delayed Effects marker/mechanism
15925024
21048042
21177254
D011471 D019833 Prostatic Neoplasms therapeutic
15256057
15378649
16925846
D013959 D019833 Thyroid Diseases marker/mechanism
21800831
D014594 D019833 Uterine Neoplasms marker/mechanism
11389053