| id | C00002526 |
|---|---|
| Name | Prunetol / Genistein / Genisteol / Sophoricol / Differenol A / 1,3,7-Trihydroxyxanthone / 5,7,4'-Trihydroxyisoflavone |
| CAS RN | 446-72-0 |
| Standard InChI | InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H |
| Standard InChI (Main Layer) | InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H |
| Phytochemical cluster | No. 15 |
|---|---|
| KCF-S cluster | No. 71 |
| By standard InChI | CHEMBL44 |
|---|---|
| By standard InChI Main Layer | CHEMBL44 |
| By LinkDB | C06563 |
|---|
| By CAS RN | D019833 |
|---|
| class name | count |
|---|---|
| rosids | 236 |
| Liliopsida | 1 |
| Magnoliophyta | 1 |
| family name | count |
|---|---|
| Fabaceae | 227 |
| Moraceae | 5 |
| Poaceae | 1 |
| Annonaceae | 1 |
| Rosaceae | 1 |
| Hypericaceae | 1 |
| Polygalaceae | 1 |
| Brassicaceae | 1 |
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | CHEMBL44 |
CHEMBL1741321
(1)
CHEMBL1909136
(2)
|
1 / 0 |
| P14061 | Estradiol 17-beta-dehydrogenase 1 | Enzyme | CHEMBL44 |
CHEMBL957998
(1)
CHEMBL957999
(1)
|
0 / 0 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | CHEMBL44 |
CHEMBL2076461
(1)
CHEMBL2076025
(1)
CHEMBL2076035 (1) CHEMBL2076038 (1) CHEMBL2076039 (1) CHEMBL2078146 (1) |
0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | CHEMBL44 |
CHEMBL1613992
(2)
CHEMBL1613995
(1)
CHEMBL1738132 (1) |
7 / 44 |
| Q16637 | Survival motor neuron protein | Unclassified protein | CHEMBL44 |
CHEMBL1613842
(3)
|
4 / 2 |
| Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | CHEMBL44 |
CHEMBL2169429
(1)
|
1 / 0 |
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | CHEMBL44 |
CHEMBL2169431
(1)
|
0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | CHEMBL44 |
CHEMBL1794367
(1)
|
1 / 1 |
| P14618 | Pyruvate kinase PKM | Enzyme | CHEMBL44 |
CHEMBL1614177
(1)
CHEMBL1614265
(1)
|
0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | CHEMBL44 |
CHEMBL1909139
(2)
|
0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | CHEMBL44 |
CHEMBL1909131
(2)
|
0 / 3 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | CHEMBL44 |
CHEMBL1909190
(2)
|
2 / 2 |
| P08246 | Neutrophil elastase | S1A | CHEMBL44 |
CHEMBL1909195
(2)
|
2 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | CHEMBL44 |
CHEMBL643650
(1)
CHEMBL1909215
(2)
|
0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | CHEMBL44 |
CHEMBL1909201
(2)
|
0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | CHEMBL44 |
CHEMBL1614079
(1)
|
0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | CHEMBL44 |
CHEMBL1909176
(2)
|
0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | CHEMBL44 |
CHEMBL1613818
(4)
|
6 / 4 |
| P29466 | Caspase-1 | C14 | CHEMBL44 |
CHEMBL1909193
(2)
|
0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | CHEMBL44 |
CHEMBL763598
(1)
CHEMBL1909198
(2)
|
0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | CHEMBL44 |
CHEMBL1909199
(2)
|
0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | CHEMBL44 |
CHEMBL1794524
(2)
CHEMBL1794552
(2)
|
0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | CHEMBL44 |
CHEMBL1909197
(2)
|
2 / 2 |
| P02545 | Prelamin-A/C | Unclassified protein | CHEMBL44 |
CHEMBL1614310
(1)
CHEMBL1614544
(2)
|
11 / 10 |
| P00519 | Tyrosine-protein kinase ABL1 | Abl | CHEMBL44 |
CHEMBL847372
(1)
CHEMBL846550
(1)
|
1 / 4 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | CHEMBL44 |
CHEMBL1614281
(1)
CHEMBL1614361
(1)
|
3 / 2 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | CHEMBL44 |
CHEMBL991725
(1)
CHEMBL990777
(1)
|
1 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | CHEMBL44 |
CHEMBL1794561
(1)
|
3 / 1 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | CHEMBL44 |
CHEMBL1794371
(2)
CHEMBL1794471
(2)
|
0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | CHEMBL44 |
CHEMBL1909123
(2)
|
1 / 2 |
| P05091 | Aldehyde dehydrogenase, mitochondrial | Oxidoreductase | CHEMBL44 |
CHEMBL641179
(1)
CHEMBL693590
(1)
CHEMBL693591 (1) CHEMBL693592 (1) CHEMBL693593 (1) |
1 / 1 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | CHEMBL44 |
CHEMBL1909092
(2)
|
0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | CHEMBL44 |
CHEMBL879881
(1)
CHEMBL689869
(1)
CHEMBL689870 (1) CHEMBL689871 (1) CHEMBL731143 (1) CHEMBL1909169 (2) |
1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | CHEMBL44 |
CHEMBL1909157
(2)
|
0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | CHEMBL44 |
CHEMBL1909156
(2)
|
0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | CHEMBL44 |
CHEMBL1909143
(2)
|
1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | CHEMBL44 |
CHEMBL1909174
(2)
|
0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | CHEMBL44 |
CHEMBL1909090
(2)
|
0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | CHEMBL44 |
CHEMBL1909093
(2)
|
0 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | CHEMBL44 |
CHEMBL862675
(1)
CHEMBL862676
(1)
|
0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | CHEMBL44 |
CHEMBL1827948
(1)
CHEMBL2075620
(1)
CHEMBL2076328 (1) CHEMBL2075832 (1) |
1 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | CHEMBL44 |
CHEMBL1909127
(2)
|
0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | CHEMBL44 |
CHEMBL1909204
(2)
|
0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | CHEMBL44 |
CHEMBL1909202
(2)
|
0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | CHEMBL44 |
CHEMBL1614027
(1)
CHEMBL1741325
(1)
CHEMBL1909135 (2) |
0 / 1 |
| P14635 | G2/mitotic-specific cyclin-B1 | Other cytosolic protein | CHEMBL44 |
CHEMBL661122
(1)
|
0 / 0 |
| P06493 | Cyclin-dependent kinase 1 | Cdc2 | CHEMBL44 |
CHEMBL661122
(1)
|
0 / 0 |
| P11802 | Cyclin-dependent kinase 4 | CMGC serine/threonine protein kinase family | CHEMBL44 |
CHEMBL666304
(1)
|
1 / 3 |
| P24385 | G1/S-specific cyclin-D1 | Other cytosolic protein | CHEMBL44 |
CHEMBL666304
(1)
|
1 / 10 |
| O75828 | Carbonyl reductase [NADPH] 3 | Enzyme | CHEMBL44 |
CHEMBL1004501
(1)
CHEMBL1004502
(1)
CHEMBL1004503 (1) |
0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | CHEMBL44 |
CHEMBL1614522
(1)
CHEMBL1614067
(1)
|
1 / 2 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | CHEMBL44 |
CHEMBL677209
(1)
CHEMBL679549
(1)
CHEMBL675515 (1) CHEMBL677887 (1) CHEMBL939337 (1) CHEMBL1012122 (1) CHEMBL941404 (2) CHEMBL941412 (1) CHEMBL970971 (1) CHEMBL1100791 (1) CHEMBL1909203 (2) |
1 / 11 |
| P11387 | DNA topoisomerase 1 | Isomerase | CHEMBL44 |
CHEMBL919339
(1)
CHEMBL919340
(1)
CHEMBL919341 (1) CHEMBL919342 (1) CHEMBL920770 (1) CHEMBL920771 (1) |
0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | CHEMBL44 |
CHEMBL920757
(1)
CHEMBL920758
(1)
CHEMBL920759 (1) CHEMBL920760 (1) CHEMBL920777 (1) CHEMBL920778 (1) CHEMBL1014685 (1) CHEMBL1014688 (1) CHEMBL1014689 (1) CHEMBL1014693 (1) CHEMBL1014697 (1) |
0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | CHEMBL44 |
CHEMBL1794376
(1)
|
2 / 3 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | CHEMBL44 |
CHEMBL1909140
(2)
|
2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | CHEMBL44 |
CHEMBL1008496
(1)
CHEMBL1909130
(2)
|
0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | CHEMBL44 |
CHEMBL1909120
(2)
|
0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | CHEMBL44 |
CHEMBL1909181
(2)
|
0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | CHEMBL44 |
CHEMBL1909164
(2)
|
0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | CHEMBL44 |
CHEMBL1909214
(2)
|
0 / 0 |
| P11926 | Ornithine decarboxylase | Lyase | CHEMBL44 |
CHEMBL970064
(1)
|
0 / 0 |
| P11474 | Steroid hormone receptor ERR1 | NR3B1 | CHEMBL44 |
CHEMBL886438
(1)
|
0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | CHEMBL44 |
CHEMBL1909175
(2)
|
0 / 0 |
| Q9Y3R4 | Sialidase-2 | Enzyme | CHEMBL44 |
CHEMBL1100507
(1)
|
0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | CHEMBL44 |
CHEMBL1909096
(2)
|
1 / 1 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | CHEMBL44 |
CHEMBL1909118
(2)
|
0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | CHEMBL44 |
CHEMBL1909166
(2)
|
1 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | CHEMBL44 |
CHEMBL1614458
(2)
|
0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | CHEMBL44 |
CHEMBL1794495
(1)
|
2 / 2 |
| P04278 | Sex hormone-binding globulin | Secreted protein | CHEMBL44 |
CHEMBL922711
(1)
|
0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | CHEMBL44 |
CHEMBL1909133
(2)
|
0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | CHEMBL44 |
CHEMBL1614456
(1)
CHEMBL1613803
(1)
|
0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | CHEMBL44 |
CHEMBL1794486
(1)
|
0 / 0 |
| P16152 | Carbonyl reductase [NADPH] 1 | Enzyme | CHEMBL44 |
CHEMBL1004498
(1)
CHEMBL1004499
(1)
CHEMBL1004500 (1) |
0 / 0 |
| O75496 | Geminin | Unclassified protein | CHEMBL44 |
CHEMBL2114780
(1)
|
0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | CHEMBL44 |
CHEMBL1613838
(2)
|
0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | CHEMBL44 |
CHEMBL2114807
(1)
|
4 / 2 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | CHEMBL44 |
CHEMBL1909158
(2)
|
0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | CHEMBL44 |
CHEMBL1909088
(2)
|
0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | CHEMBL44 |
CHEMBL1909142
(2)
|
0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | CHEMBL44 |
CHEMBL1909101
(2)
|
0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | CHEMBL44 |
CHEMBL1909141
(2)
|
1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | CHEMBL44 |
CHEMBL1909180
(2)
|
0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | CHEMBL44 |
CHEMBL679353
(1)
CHEMBL677954
(1)
CHEMBL678669 (1) CHEMBL677744 (1) CHEMBL673864 (1) CHEMBL682160 (1) CHEMBL682161 (1) CHEMBL682162 (1) CHEMBL876871 (1) CHEMBL682168 (1) CHEMBL682169 (1) CHEMBL678095 (1) CHEMBL677051 (1) CHEMBL677223 (1) CHEMBL708330 (1) CHEMBL708331 (1) CHEMBL847349 (1) CHEMBL850899 (1) CHEMBL850379 (1) CHEMBL850380 (1) CHEMBL826030 (1) CHEMBL828540 (2) CHEMBL832634 (1) CHEMBL831137 (1) CHEMBL829091 (1) CHEMBL829115 (1) CHEMBL830453 (2) CHEMBL830748 (1) CHEMBL831723 (1) CHEMBL838181 (1) CHEMBL880931 (1) CHEMBL884157 (1) CHEMBL868723 (1) CHEMBL868724 (1) CHEMBL860987 (1) CHEMBL860991 (1) CHEMBL860992 (1) CHEMBL860995 (1) CHEMBL860997 (1) CHEMBL909844 (1) CHEMBL909845 (1) CHEMBL888712 (1) CHEMBL891639 (1) CHEMBL895879 (1) CHEMBL898604 (1) CHEMBL898607 (1) CHEMBL965155 (1) CHEMBL1008128 (1) CHEMBL1664695 (1) CHEMBL1909146 (2) |
0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | CHEMBL44 |
CHEMBL1909104
(2)
|
0 / 0 |
| P15121 | Aldose reductase | Enzyme | CHEMBL44 |
CHEMBL1942674
(1)
|
0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | CHEMBL44 |
CHEMBL1909144
(2)
|
0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | CHEMBL44 |
CHEMBL1909100
(2)
|
0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | CHEMBL44 |
CHEMBL1909167
(2)
|
1 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | CHEMBL44 |
CHEMBL1909129
(2)
|
0 / 0 |
| P08311 | Cathepsin G | S1A | CHEMBL44 |
CHEMBL1909194
(2)
|
0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | CHEMBL44 |
CHEMBL1909110
(2)
|
1 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | CHEMBL44 |
CHEMBL2114788
(1)
CHEMBL2114931
(1)
|
0 / 0 |
| P03956 | Interstitial collagenase | M10A | CHEMBL44 |
CHEMBL1909196
(2)
|
0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | CHEMBL44 |
CHEMBL1909119
(2)
|
0 / 0 |
| Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | CHEMBL44 |
CHEMBL2169430
(1)
|
1 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | CHEMBL44 |
CHEMBL1794423
(1)
CHEMBL1963893
(1)
|
0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | CHEMBL44 |
CHEMBL1052488
(1)
CHEMBL1052489
(1)
CHEMBL1052492 (1) CHEMBL1052494 (1) CHEMBL1909150 (2) |
0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | CHEMBL44 |
CHEMBL1909171
(2)
|
2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | CHEMBL44 |
CHEMBL1909170
(2)
|
0 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | CHEMBL44 |
CHEMBL827396
(1)
CHEMBL987972
(1)
|
2 / 2 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | CHEMBL44 |
CHEMBL1909122
(2)
|
0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | CHEMBL44 |
CHEMBL1909109
(2)
|
2 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | CHEMBL44 |
CHEMBL1059360
(1)
CHEMBL1059361
(1)
CHEMBL1794510 (2) |
5 / 3 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | CHEMBL44 |
CHEMBL1909205
(2)
|
5 / 10 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | CHEMBL44 |
CHEMBL1909172
(2)
|
1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | CHEMBL44 |
CHEMBL1909114
(2)
|
0 / 0 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | CHEMBL44 |
CHEMBL816861
(1)
CHEMBL843059
(1)
|
0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | CHEMBL44 |
CHEMBL1909125
(2)
|
0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | CHEMBL44 |
CHEMBL1909126
(2)
|
3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | CHEMBL44 |
CHEMBL1909108
(2)
|
0 / 0 |
| P04745 | Alpha-amylase 1 | Enzyme | CHEMBL44 |
CHEMBL964479
(2)
|
0 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | CHEMBL44 |
CHEMBL1794437
(2)
|
0 / 0 |
| Q13133 | Oxysterols receptor LXR-alpha | NR1H3 | CHEMBL44 |
CHEMBL933514
(1)
|
0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | CHEMBL44 |
CHEMBL1909124
(2)
|
1 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | CHEMBL44 |
CHEMBL1613808
(2)
CHEMBL1909200
(2)
|
0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | CHEMBL44 |
CHEMBL1909207
(2)
|
2 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | CHEMBL44 |
CHEMBL1741322
(1)
CHEMBL1909132
(2)
|
0 / 0 |
| P55055 | Oxysterols receptor LXR-beta | NR1H3 | CHEMBL44 |
CHEMBL933515
(1)
|
0 / 0 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | CHEMBL44 |
CHEMBL1687393
(1)
CHEMBL1687394
(1)
CHEMBL2076473 (1) CHEMBL2076243 (1) CHEMBL2076824 (1) CHEMBL2076838 (1) CHEMBL2075868 (1) CHEMBL2078552 (1) |
2 / 0 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | CHEMBL44 |
CHEMBL1006005
(1)
|
1 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | CHEMBL44 |
CHEMBL1614038
(5)
|
2 / 2 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | CHEMBL44 |
CHEMBL1614342
(2)
|
1 / 1 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | CHEMBL44 |
CHEMBL1614171
(1)
|
5 / 2 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | CHEMBL44 |
CHEMBL1738588
(1)
CHEMBL1738675
(1)
CHEMBL1737868 (1) CHEMBL1738317 (1) |
0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | CHEMBL44 |
CHEMBL1909186
(2)
|
0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | CHEMBL44 |
CHEMBL679353
(1)
CHEMBL676806
(1)
CHEMBL883442 (1) CHEMBL676811 (1) CHEMBL676818 (1) CHEMBL676819 (1) CHEMBL679323 (1) CHEMBL679893 (1) CHEMBL682303 (1) CHEMBL708330 (1) CHEMBL708331 (1) CHEMBL841902 (1) CHEMBL841903 (1) CHEMBL841904 (1) CHEMBL847349 (1) CHEMBL850899 (1) CHEMBL850379 (1) CHEMBL850380 (1) CHEMBL826030 (1) CHEMBL827788 (2) CHEMBL832786 (1) CHEMBL831155 (1) CHEMBL829540 (1) CHEMBL829115 (1) CHEMBL830453 (2) CHEMBL830748 (1) CHEMBL831723 (1) CHEMBL881884 (1) CHEMBL884157 (1) CHEMBL863381 (1) CHEMBL868724 (1) CHEMBL860989 (1) CHEMBL860991 (1) CHEMBL860997 (1) CHEMBL909843 (1) CHEMBL909845 (1) CHEMBL888711 (1) CHEMBL891640 (1) CHEMBL895878 (1) CHEMBL898603 (1) CHEMBL898606 (1) CHEMBL965154 (1) CHEMBL946607 (1) CHEMBL999946 (1) CHEMBL999947 (1) CHEMBL1664694 (1) CHEMBL1794364 (2) CHEMBL1794542 (1) CHEMBL1909145 (2) |
1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | CHEMBL44 |
CHEMBL1909091
(2)
|
1 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | CHEMBL44 |
CHEMBL1909212
(2)
|
1 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | CHEMBL44 |
CHEMBL1909211
(2)
|
0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | CHEMBL44 |
CHEMBL1909105
(2)
|
0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | CHEMBL44 |
CHEMBL1909182
(2)
|
0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | CHEMBL44 |
CHEMBL1909173
(2)
|
0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | CHEMBL44 |
CHEMBL1909113
(2)
|
0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | CHEMBL44 |
CHEMBL1909187
(2)
|
0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | CHEMBL44 |
CHEMBL1909168
(2)
|
0 / 0 |
| O95718 | Steroid hormone receptor ERR2 | NR3B2 | CHEMBL44 |
CHEMBL886439
(1)
|
1 / 1 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | CHEMBL44 |
CHEMBL920238
(1)
|
0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | CHEMBL44 |
CHEMBL1614240
(2)
|
0 / 0 |
| Q8WUI4 | Histone deacetylase 7 | Hydrolase | CHEMBL44 |
CHEMBL1267835
(1)
|
0 / 0 |
| P31749 | RAC-alpha serine/threonine-protein kinase | Akt | CHEMBL44 |
CHEMBL853526
(1)
|
4 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | CHEMBL44 |
CHEMBL1613777
(2)
CHEMBL1741323
(1)
CHEMBL1909134 (2) |
1 / 1 |
| P37059 | Estradiol 17-beta-dehydrogenase 2 | Enzyme | CHEMBL44 |
CHEMBL958788
(1)
CHEMBL958789
(1)
|
0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL44 |
CHEMBL1614108
(2)
CHEMBL1613886
(2)
CHEMBL1741324 (1) CHEMBL1909138 (2) |
0 / 1 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | CHEMBL44 |
CHEMBL1909137
(2)
|
0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | CHEMBL44 |
CHEMBL1614421
(5)
CHEMBL1614502
(1)
|
4 / 3 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | CHEMBL44 |
CHEMBL1738402
(1)
|
0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | CHEMBL44 |
CHEMBL2114890
(2)
|
0 / 0 |
| O43451 | Maltase-glucoamylase, intestinal | Hydrolase | CHEMBL44 |
CHEMBL646886
(1)
CHEMBL646887
(1)
CHEMBL872366 (1) |
0 / 0 |
| P10275 | Androgen receptor | NR3C4 | CHEMBL44 |
CHEMBL1052486
(1)
CHEMBL1052487
(1)
CHEMBL1052490 (1) CHEMBL1052491 (1) CHEMBL1052493 (1) CHEMBL1794321 (1) CHEMBL1794560 (1) |
3 / 4 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | CHEMBL44 |
CHEMBL1909094
(2)
|
1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | CHEMBL44 |
CHEMBL1909087
(2)
|
0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | CHEMBL44 |
CHEMBL1909213
(2)
|
0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | CHEMBL44 |
CHEMBL1909089
(2)
|
0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | CHEMBL44 |
CHEMBL1909116
(2)
|
1 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | CHEMBL44 |
CHEMBL1909206
(2)
|
0 / 1 |
| P35869 | Aryl hydrocarbon receptor | Transcription Factor | CHEMBL44 |
CHEMBL2114849
(2)
|
0 / 0 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | CHEMBL44 |
CHEMBL1909128
(2)
|
0 / 0 |
| P43405 | Tyrosine-protein kinase SYK | Syk | CHEMBL44 |
CHEMBL1022010
(1)
|
0 / 0 |
| Q06278 | Aldehyde oxidase | Enzyme | CHEMBL44 |
CHEMBL1640077
(1)
|
0 / 1 |
| P40225 | Thrombopoietin | Unclassified protein | CHEMBL44 |
CHEMBL1614086
(1)
CHEMBL1614034
(1)
|
1 / 1 |
| P56937 | 3-keto-steroid reductase | Enzyme | CHEMBL44 |
CHEMBL1106724
(1)
CHEMBL1106725
(1)
|
0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | CHEMBL44 |
CHEMBL1738442
(1)
|
0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | CHEMBL44 |
CHEMBL1614364
(1)
|
1 / 1 |
| O00255 | Menin | Unclassified protein | CHEMBL44 |
CHEMBL1614257
(2)
CHEMBL1614531
(1)
|
2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | CHEMBL44 |
CHEMBL1614257
(2)
CHEMBL1614531
(1)
|
1 / 3 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | CHEMBL44 |
CHEMBL879881
(1)
CHEMBL689869
(1)
CHEMBL689870 (1) CHEMBL689871 (1) CHEMBL731143 (1) |
0 / 0 |
| P42684 | Abelson tyrosine-protein kinase 2 | Abl | CHEMBL44 |
CHEMBL846550
(1)
|
0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | CHEMBL44 |
CHEMBL2114738
(1)
|
0 / 0 |
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| D019833 | 18 |
ABAT
GABA-AT GABAT NPD009 |
4-aminobutyrate aminotransferase (EC:2.6.1.19 2.6.1.22) | ESR2 promotes the reaction [Genistein results in decreased expression of ABAT protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 18 |
ABAT
GABA-AT GABAT NPD009 |
4-aminobutyrate aminotransferase (EC:2.6.1.19 2.6.1.22) | Genistein results in decreased expression of ABAT protein |
decreases expression
|
protein |
20884965
|
| D019833 | 19 |
ABCA1
ABC-1 ABC1 CERP HDLDT1 TGD |
ATP-binding cassette, sub-family A (ABC1), member 1 | [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ABCA1 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
16963248
|
| D019833 | 19 |
ABCA1
ABC-1 ABC1 CERP HDLDT1 TGD |
ATP-binding cassette, sub-family A (ABC1), member 1 | Genistein results in increased expression of ABCA1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 5243 |
ABCB1
ABC20 CD243 CLCS GP170 MDR1 P-GP PGY1 |
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) | Genistein results in increased expression of ABCB1 protein |
increases expression
|
protein |
18634814
|
| D019833 | 4363 |
ABCC1
ABC29 ABCC GS-X MRP MRP1 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | Genistein affects the activity of ABCC1 protein |
affects activity
|
protein |
9334814
|
| D019833 | 4363 |
ABCC1
ABC29 ABCC GS-X MRP MRP1 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | Genistein analog results in decreased activity of ABCC1 protein |
decreases activity
|
protein |
15916776
|
| D019833 | 4363 |
ABCC1
ABC29 ABCC GS-X MRP MRP1 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | Genistein results in decreased activity of ABCC1 protein |
decreases activity
|
protein |
15581599
|
| D019833 | 85320 |
ABCC11
EWWD MRP8 WW |
ATP-binding cassette, sub-family C (CFTR/MRP), member 11 | Genistein results in increased expression of ABCC11 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 150000 |
ABCC13
C21orf73 PRED6 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene | Genistein results in increased expression of ABCC13 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 1244 |
ABCC2
ABC30 CMOAT DJS MRP2 cMRP |
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | Genistein inhibits the reaction [ABCC2 protein affects the export of ochratoxin A] |
affects export
/ decreases reaction |
protein |
15955639
|
| D019833 | 1244 |
ABCC2
ABC30 CMOAT DJS MRP2 cMRP |
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | Genistein promotes the reaction [RXRA protein binds to ABCC2 promoter] |
affects binding
/ increases reaction |
promoter |
21689630
|
| D019833 | 1244 |
ABCC2
ABC30 CMOAT DJS MRP2 cMRP |
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | Genistein results in increased expression of ABCC2 mRNA |
increases expression
|
mRNA |
21689630
|
| D019833 | 1244 |
ABCC2
ABC30 CMOAT DJS MRP2 cMRP |
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | Genistein results in increased expression of ABCC2 protein |
increases expression
|
protein |
21689630
|
| D019833 | 1244 |
ABCC2
ABC30 CMOAT DJS MRP2 cMRP |
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | resveratrol inhibits the reaction [Genistein promotes the reaction [RXRA protein binds to ABCC2 promoter]] |
affects binding
/ decreases reaction / increases reaction |
promoter |
21689630
|
| D019833 | 1244 |
ABCC2
ABC30 CMOAT DJS MRP2 cMRP |
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | resveratrol inhibits the reaction [Genistein results in increased expression of ABCC2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
21689630
|
| D019833 | 1244 |
ABCC2
ABC30 CMOAT DJS MRP2 cMRP |
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | resveratrol inhibits the reaction [Genistein results in increased expression of ABCC2 protein] |
decreases reaction
/ increases expression |
protein |
21689630
|
| D019833 | 8714 |
ABCC3
ABC31 EST90757 MLP2 MOAT-D MRP3 cMOAT2 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | Genistein results in decreased expression of ABCC3 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 83451 |
ABHD11
WBSCR21 |
abhydrolase domain containing 11 | Genistein results in increased expression of ABHD11 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 10006 |
ABI1
ABI-1 ABLBP4 E3B1 NAP1BP SSH3BP SSH3BP1 |
abl-interactor 1 | Genistein results in increased expression of ABI1 mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 1238 |
ACKR2
CCBP2 CCR10 CCR9 CMKBR9 D6 hD6 |
atypical chemokine receptor 2 | Genistein results in decreased expression of ACKR2 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 47 |
ACLY
ACL ATPCL CLATP |
ATP citrate lyase (EC:2.3.3.8) | ESR2 promotes the reaction [Genistein results in decreased expression of ACLY protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 47 |
ACLY
ACL ATPCL CLATP |
ATP citrate lyase (EC:2.3.3.8) | Genistein results in decreased expression of ACLY protein |
decreases expression
|
protein |
20884965
|
| D019833 | 47 |
ACLY
ACL ATPCL CLATP |
ATP citrate lyase (EC:2.3.3.8) | Genistein results in increased expression of ACLY mRNA |
increases expression
|
mRNA |
20706672
|
| D019833 | 51 |
ACOX1
ACOX PALMCOX SCOX |
acyl-CoA oxidase 1, palmitoyl (EC:1.3.3.6) | ESR2 promotes the reaction [Genistein results in decreased expression of ACOX1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 51 |
ACOX1
ACOX PALMCOX SCOX |
acyl-CoA oxidase 1, palmitoyl (EC:1.3.3.6) | Genistein results in decreased expression of ACOX1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 55 |
ACPP
5'-NT ACP-3 ACP3 PAP |
acid phosphatase, prostate (EC:3.1.3.2 3.1.3.5) | Genistein results in decreased expression of ACPP mRNA |
decreases expression
|
mRNA |
12391264
|
| D019833 | 2181 |
ACSL3
ACS3 FACL3 PRO2194 |
acyl-CoA synthetase long-chain family member 3 (EC:6.2.1.3) | Genistein results in increased expression of ACSL3 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 59 |
ACTA2
AAT6 ACTSA MYMY5 |
actin, alpha 2, smooth muscle, aorta | Genistein results in decreased expression of ACTA2 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 345651 |
ACTBL2
ACT |
actin, beta-like 2 | ESR1 promotes the reaction [Genistein results in decreased expression of ACTBL2 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 345651 |
ACTBL2
ACT |
actin, beta-like 2 | Genistein results in decreased expression of ACTBL2 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 95 |
ACY1
ACY-1 ACY1D |
aminoacylase 1 (EC:3.5.1.14) | ESR2 promotes the reaction [Genistein results in increased expression of ACY1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 95 |
ACY1
ACY-1 ACY1D |
aminoacylase 1 (EC:3.5.1.14) | Genistein results in increased expression of ACY1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 8751 |
ADAM15
MDC15 |
ADAM metallopeptidase domain 15 | Genistein results in decreased expression of ADAM15 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 11173 |
ADAMTS7
ADAM-TS_7 ADAM-TS7 ADAMTS-7 |
ADAM metallopeptidase with thrombospondin type 1 motif, 7 (EC:3.4.24.-) | Genistein results in increased expression of ADAMTS7 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 56999 |
ADAMTS9
|
ADAM metallopeptidase with thrombospondin type 1 motif, 9 | Genistein results in increased expression of ADAMTS9 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 119 |
ADD2
ADDB |
adducin 2 (beta) | [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ADD2 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
16963248
|
| D019833 | 10974 |
ADIRF
AFRO APM2 C10orf116 apM-2 |
adipogenesis regulatory factor | Genistein results in increased expression of ADIRF mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 152 |
ADRA2C
ADRA2L2 ADRA2RL2 ADRARL2 ALPHA2CAR |
adrenoceptor alpha 2C | Genistein results in increased expression of ADRA2C mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 158 |
ADSL
AMPS ASASE ASL |
adenylosuccinate lyase (EC:4.3.2.2) | ESR2 promotes the reaction [Genistein results in decreased expression of ADSL protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 158 |
ADSL
AMPS ASASE ASL |
adenylosuccinate lyase (EC:4.3.2.2) | Genistein results in decreased expression of ADSL protein |
decreases expression
|
protein |
20884965
|
| D019833 | 10555 |
AGPAT2
1-AGPAT2 BSCL BSCL1 LPAAB LPAAT-beta |
1-acylglycerol-3-phosphate O-acyltransferase 2 (EC:2.3.1.51) | Genistein results in increased expression of AGPAT2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 10551 |
AGR2
AG2 GOB-4 HAG-2 PDIA17 XAG-2 |
anterior gradient 2 | Genistein results in increased expression of AGR2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 196 |
AHR
bHLHe76 |
aryl hydrocarbon receptor | Genistein affects the activity of AHR protein |
affects activity
|
protein |
19286049
|
| D019833 | 196 |
AHR
bHLHe76 |
aryl hydrocarbon receptor | Genistein binds to AHR protein |
affects binding
|
protein |
20436506
|
| D019833 | 196 |
AHR
bHLHe76 |
aryl hydrocarbon receptor | [Genistein co-treated with Methylcholanthrene] affects the activity of AHR protein |
affects activity
/ affects cotreatment |
protein |
19286049
|
| D019833 | 196 |
AHR
bHLHe76 |
aryl hydrocarbon receptor | [Genistein co-treated with Tetrachlorodibenzodioxin] affects the activity of AHR protein |
affects activity
/ affects cotreatment |
protein |
19286049
|
| D019833 | 196 |
AHR
bHLHe76 |
aryl hydrocarbon receptor | Genistein inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of AHR protein] |
affects localization
/ decreases reaction |
protein |
20057149
|
| D019833 | 205 |
AK4
AK_4 AK3 AK3L1 AK3L2 |
adenylate kinase 4 (EC:2.7.4.10 2.7.4.6) | Genistein results in increased expression of AK4 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 207 |
AKT1
AKT CWS6 PKB PKB-ALPHA PRKBA RAC RAC-ALPHA |
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) | Genistein binds to AKT1 protein |
affects binding
|
protein |
16789737
|
| D019833 | 207 |
AKT1
AKT CWS6 PKB PKB-ALPHA PRKBA RAC RAC-ALPHA |
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) | Genistein inhibits the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases reaction
/ increases activity / increases phosphorylation |
protein |
21078540
|
| D019833 | 207 |
AKT1
AKT CWS6 PKB PKB-ALPHA PRKBA RAC RAC-ALPHA |
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) | Genistein inhibits the reaction [EGF protein results in increased activity of AKT1 protein] |
decreases reaction
/ increases activity |
protein |
18431742
|
| D019833 | 207 |
AKT1
AKT CWS6 PKB PKB-ALPHA PRKBA RAC RAC-ALPHA |
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) | Genistein results in decreased phosphorylation of AKT1 protein |
decreases phosphorylation
|
protein |
15829497
18431742 19038232 21078540 |
| D019833 | 207 |
AKT1
AKT CWS6 PKB PKB-ALPHA PRKBA RAC RAC-ALPHA |
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) | [[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased activity of FOXO3 protein |
decreases activity
/ increases activity / increases expression |
protein |
18431742
|
| D019833 | 207 |
AKT1
AKT CWS6 PKB PKB-ALPHA PRKBA RAC RAC-ALPHA |
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) | [[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased expression of TP53 protein |
decreases activity
/ increases expression |
protein |
18431742
|
| D019833 | 207 |
AKT1
AKT CWS6 PKB PKB-ALPHA PRKBA RAC RAC-ALPHA |
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) | Tretinoin inhibits the reaction [Genistein results in decreased phosphorylation of AKT1 protein] |
decreases phosphorylation
/ decreases reaction |
protein |
19038232
|
| D019833 | 208 |
AKT2
HIHGHH PKBB PKBBETA PRKBB RAC-BETA |
v-akt murine thymoma viral oncogene homolog 2 (EC:2.7.11.1) | Genistein results in decreased expression of AKT2 mRNA |
decreases expression
|
mRNA |
15257099
|
| D019833 | 220 |
ALDH1A3
ALDH1A6 ALDH6 MCOP8 RALDH3 |
aldehyde dehydrogenase 1 family, member A3 (EC:1.2.1.5) | Genistein results in decreased expression of ALDH1A3 mRNA |
decreases expression
|
mRNA |
15378649
|
| D019833 | 224 |
ALDH3A2
ALDH10 FALDH SLS |
aldehyde dehydrogenase 3 family, member A2 (EC:1.2.1.3) | Genistein results in increased expression of ALDH3A2 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 229 |
ALDOB
ALDB ALDO2 |
aldolase B, fructose-bisphosphate (EC:4.1.2.13) | Genistein results in decreased expression of ALDOB mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 248 |
ALPI
IAP |
alkaline phosphatase, intestinal (EC:3.1.3.1) | Genistein results in increased expression of ALPI mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 249 |
ALPL
AP-TNAP APTNAP HOPS TNAP TNSALP |
alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) | fulvestrant inhibits the reaction [[Genistein binds to ESR1 protein] which results in increased activity of ALPL protein] |
affects binding
/ decreases reaction / increases activity |
protein |
12650720
|
| D019833 | 249 |
ALPL
AP-TNAP APTNAP HOPS TNAP TNSALP |
alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) | [Genistein binds to ESR1 protein] which results in increased activity of ALPL protein |
affects binding
/ increases activity |
protein |
12650720
|
| D019833 | 250 |
ALPP
ALP PALP PLAP PLAP-1 |
alkaline phosphatase, placental (EC:3.1.3.1) | Genistein results in increased expression of ALPP mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 251 |
ALPPL2
ALPG ALPPL GCAP |
alkaline phosphatase, placental-like 2 (EC:3.1.3.1) | Genistein results in increased expression of ALPPL2 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 196394 |
AMN1
|
antagonist of mitotic exit network 1 homolog (S. cerevisiae) | Genistein results in increased expression of AMN1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 271 |
AMPD2
|
adenosine monophosphate deaminase 2 (EC:3.5.4.6) | Genistein results in increased expression of AMPD2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 64682 |
ANAPC1
APC1 MCPR TSG24 |
anaphase promoting complex subunit 1 | Genistein results in increased expression of ANAPC1 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 284 |
ANGPT1
AGP1 AGPT ANG1 |
angiopoietin 1 | Genistein results in decreased expression of ANGPT1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 286 |
ANK1
ANK SPH1 SPH2 |
ankyrin 1, erythrocytic | Genistein results in decreased expression of ANK1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 54522 |
ANKRD16
|
ankyrin repeat domain 16 | Genistein results in decreased expression of ANKRD16 mRNA |
decreases expression
|
mRNA |
18847459
|
| D019833 | 91074 |
ANKRD30A
NY-BR-1 |
ankyrin repeat domain 30A | Genistein results in increased expression of ANKRD30A mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 57730 |
ANKRD36B
KIAA1641 |
ankyrin repeat domain 36B | ESR2 promotes the reaction [Genistein results in increased expression of ANKRD36B protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 57730 |
ANKRD36B
KIAA1641 |
ankyrin repeat domain 36B | Genistein results in increased expression of ANKRD36B protein |
increases expression
|
protein |
20884965
|
| D019833 | 55107 |
ANO1
DOG1 ORAOV2 TAOS2 TMEM16A |
anoctamin 1, calcium activated chloride channel | Genistein results in increased expression of ANO1 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 8125 |
ANP32A
C15orf1 HPPCn I1PP2A LANP MAPM PHAP1 PHAPI PP32 |
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | Genistein results in decreased expression of ANP32A mRNA |
decreases expression
|
mRNA |
18847459
|
| D019833 | 301 |
ANXA1
ANX1 LPC1 |
annexin A1 | ESR2 promotes the reaction [Genistein results in decreased expression of ANXA1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 301 |
ANXA1
ANX1 LPC1 |
annexin A1 | Genistein results in decreased expression of ANXA1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 306 |
ANXA3
ANX3 |
annexin A3 (EC:3.1.4.43) | ESR2 promotes the reaction [Genistein results in decreased expression of ANXA3 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 306 |
ANXA3
ANX3 |
annexin A3 (EC:3.1.4.43) | Genistein results in decreased expression of ANXA3 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 8905 |
AP1S2
MGC:1902 MRX59 MRXS21 MRXSF SIGMA1B |
adaptor-related protein complex 1, sigma 2 subunit | Genistein results in increased expression of AP1S2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 317 |
APAF1
APAF-1 CED4 |
apoptotic peptidase activating factor 1 | Genistein results in increased expression of APAF1 mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 334 |
APLP2
APLP-2 APPH APPL2 CDEBP |
amyloid beta (A4) precursor-like protein 2 | ESR1 promotes the reaction [Genistein results in decreased expression of APLP2 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 334 |
APLP2
APLP-2 APPH APPL2 CDEBP |
amyloid beta (A4) precursor-like protein 2 | Genistein results in decreased expression of APLP2 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 334 |
APLP2
APLP-2 APPH APPL2 CDEBP |
amyloid beta (A4) precursor-like protein 2 | Genistein results in decreased expression of APLP2 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 9582 |
APOBEC3B
A3B APOBEC1L ARCD3 ARP4 DJ742C19.2 PHRBNL bK150C2.2 |
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | Genistein results in increased expression of APOBEC3B mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 347 |
APOD
|
apolipoprotein D | Genistein results in increased expression of APOD mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 353 |
APRT
AMP APRTD |
adenine phosphoribosyltransferase (EC:2.4.2.7) | ESR2 promotes the reaction [Genistein results in increased expression of APRT protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 353 |
APRT
AMP APRTD |
adenine phosphoribosyltransferase (EC:2.4.2.7) | Genistein results in increased expression of APRT protein |
increases expression
|
protein |
20884965
|
| D019833 | 358 |
AQP1
AQP-CHIP CHIP28 CO |
aquaporin 1 | Genistein results in decreased expression of AQP1 mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 360 |
AQP3
AQP-3 GIL |
aquaporin 3 (Gill blood group) | Genistein results in increased expression of AQP3 mRNA |
increases expression
|
mRNA |
20706672
|
| D019833 | 367 |
AR
AIS DHTR HUMARA HYSP1 KD NR3C4 SBMA SMAX1 TFM |
androgen receptor | Genistein results in decreased expression of AR mRNA |
decreases expression
|
mRNA |
12391264
20706672 |
| D019833 | 367 |
AR
AIS DHTR HUMARA HYSP1 KD NR3C4 SBMA SMAX1 TFM |
androgen receptor | Genistein results in increased activity of and results in increased localization of AR protein |
increases activity
/ increases localization |
protein |
12391264
|
| D019833 | 367 |
AR
AIS DHTR HUMARA HYSP1 KD NR3C4 SBMA SMAX1 TFM |
androgen receptor | Genistein results in increased activity of AR protein mutant form |
increases activity
|
protein |
12391264
|
| D019833 | 367 |
AR
AIS DHTR HUMARA HYSP1 KD NR3C4 SBMA SMAX1 TFM |
androgen receptor | Genistein results in increased expression of AR protein |
increases expression
|
protein |
12391264
|
| D019833 | 374 |
AREG
AR CRDGF SDGF |
amphiregulin | Genistein results in increased expression of AREG mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 375 |
ARF1
|
ADP-ribosylation factor 1 | Genistein results in decreased expression of ARF1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 396 |
ARHGDIA
GDIA1 NPHS8 RHOGDI RHOGDI-1 |
Rho GDP dissociation inhibitor (GDI) alpha | Genistein results in decreased expression of ARHGDIA mRNA |
decreases expression
|
mRNA |
15159206
15757668 |
| D019833 | 403 |
ARL3
ARFL3 |
ADP-ribosylation factor-like 3 | Genistein results in increased expression of ARL3 mRNA |
increases expression
|
mRNA |
16474171
18847459 |
| D019833 | 83787 |
ARMC10
PNAS-112 PNAS112 SVH |
armadillo repeat containing 10 | ESR2 promotes the reaction [Genistein results in increased expression of ARMC10 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 83787 |
ARMC10
PNAS-112 PNAS112 SVH |
armadillo repeat containing 10 | Genistein results in increased expression of ARMC10 protein |
increases expression
|
protein |
20884965
|
| D019833 | 51566 |
ARMCX3
ALEX3 dJ545K15.2 |
armadillo repeat containing, X-linked 3 | ESR2 promotes the reaction [Genistein results in decreased expression of ARMCX3 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 51566 |
ARMCX3
ALEX3 dJ545K15.2 |
armadillo repeat containing, X-linked 3 | Genistein results in decreased expression of ARMCX3 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 405 |
ARNT
HIF-1-beta HIF-1beta HIF1-beta HIF1B HIF1BETA TANGO bHLHe2 |
aryl hydrocarbon receptor nuclear translocator | Genistein affects the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]] |
affects binding
/ affects reaction / increases reaction |
protein |
10939628
|
| D019833 | 405 |
ARNT
HIF-1-beta HIF-1beta HIF1-beta HIF1B HIF1BETA TANGO bHLHe2 |
aryl hydrocarbon receptor nuclear translocator | Genistein affects the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]] |
affects binding
/ affects reaction / increases reaction |
protein |
10939628
|
| D019833 | 414 |
ARSD
ASD |
arylsulfatase D (EC:3.1.6.1) | Genistein results in decreased expression of ARSD mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 427 |
ASAH1
AC ACDase ASAH PHP PHP32 SMAPME |
N-acylsphingosine amidohydrolase (acid ceramidase) 1 (EC:3.5.1.23) | Genistein results in decreased expression of ASAH1 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 440 |
ASNS
TS11 |
asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) | ESR1 promotes the reaction [Genistein results in increased expression of ASNS protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 440 |
ASNS
TS11 |
asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) | Genistein results in increased expression of ASNS mRNA |
increases expression
|
mRNA |
15757668
18444173 |
| D019833 | 440 |
ASNS
TS11 |
asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) | Genistein results in increased expression of ASNS protein |
increases expression
|
protein |
20884965
|
| D019833 | 259266 |
ASPM
ASP Calmbp1 MCPH5 |
asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | Genistein affects the expression of ASPM mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 259266 |
ASPM
ASP Calmbp1 MCPH5 |
asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | Genistein results in increased expression of ASPM mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 80150 |
ASRGL1
ALP ALP1 CRASH |
asparaginase like 1 (EC:3.5.1.1 3.4.19.5) | Genistein results in increased expression of ASRGL1 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 445 |
ASS1
ASS CTLN1 |
argininosuccinate synthase 1 (EC:6.3.4.5) | Genistein results in increased expression of ASS1 mRNA |
increases expression
|
mRNA |
15757668
|
| D019833 | 29028 |
ATAD2
ANCCA PRO2000 |
ATPase family, AAA domain containing 2 (EC:3.6.1.3) | Genistein results in increased expression of ATAD2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 467 |
ATF3
|
activating transcription factor 3 | Genistein results in decreased expression of ATF3 mRNA |
decreases expression
|
mRNA |
16474171
20884965 |
| D019833 | 467 |
ATF3
|
activating transcription factor 3 | Genistein results in increased expression of ATF3 mRNA |
increases expression
|
mRNA |
21554132
|
| D019833 | 467 |
ATF3
|
activating transcription factor 3 | Genistein results in increased expression of ATF3 protein |
increases expression
|
protein |
21554132
|
| D019833 | 9474 |
ATG5
APG5 APG5-LIKE APG5L ASP hAPG5 |
autophagy related 5 | Genistein results in increased expression of ATG5 mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 472 |
ATM
AT1 ATA ATC ATD ATDC ATE TEL1 TELO1 |
ataxia telangiectasia mutated (EC:2.7.11.1) | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of ATM protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 472 |
ATM
AT1 ATA ATC ATD ATDC ATE TEL1 TELO1 |
ataxia telangiectasia mutated (EC:2.7.11.1) | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of ATM protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 472 |
ATM
AT1 ATA ATC ATD ATDC ATE TEL1 TELO1 |
ataxia telangiectasia mutated (EC:2.7.11.1) | Caffeine inhibits the reaction [Genistein results in increased phosphorylation of ATM protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 472 |
ATM
AT1 ATA ATC ATD ATDC ATE TEL1 TELO1 |
ataxia telangiectasia mutated (EC:2.7.11.1) | Genistein results in increased phosphorylation of ATM protein |
increases phosphorylation
|
protein |
19038232
|
| D019833 | 472 |
ATM
AT1 ATA ATC ATD ATDC ATE TEL1 TELO1 |
ataxia telangiectasia mutated (EC:2.7.11.1) | U 0126 inhibits the reaction [Genistein results in increased phosphorylation of ATM protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 1822 |
ATN1
B37 D12S755E DRPLA HRS NOD |
atrophin 1 | Genistein results in decreased expression of ATN1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 481 |
ATP1B1
ATP1B |
ATPase, Na+/K+ transporting, beta 1 polypeptide | Genistein results in decreased expression of ATP1B1 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 514 |
ATP5E
ATPE MC5DN3 |
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit (EC:3.6.3.14) | Genistein results in increased expression of ATP5E mRNA |
increases expression
|
mRNA |
16705744
|
| D019833 | 23545 |
ATP6V0A2
A2 ARCL ARCL2A ATP6A2 ATP6N1D J6B7 RTF STV1 TJ6 TJ6M TJ6S VPH1 WSS |
ATPase, H+ transporting, lysosomal V0 subunit a2 (EC:3.6.3.6) | [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ATP6V0A2 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
16963248
|
| D019833 | 11273 |
ATXN2L
A2D A2LG A2LP A2RP |
ataxin 2-like | Genistein results in decreased expression of ATXN2L mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 6790 |
AURKA
AIK ARK1 AURA AURORA2 BTAK PPP1R47 STK15 STK6 STK7 |
aurora kinase A (EC:2.7.11.1) | Genistein results in increased expression of AURKA mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 9212 |
AURKB
AIK2 AIM-1 AIM1 ARK2 AurB IPL1 PPP1R48 STK12 STK5 aurkb-sv1 aurkb-sv2 |
aurora kinase B (EC:2.7.11.1) | Genistein results in increased expression of AURKB mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 2683 |
B4GALT1
B4GAL-T1 CDG2D GGTB2 GT1 GTB beta4Gal-T1 |
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (EC:2.4.1.22 2.4.1.90 2.4.1.38) | Genistein results in increased expression of B4GALT1 mRNA |
increases expression
|
mRNA |
14605097
|
| D019833 | 9531 |
BAG3
BAG-3 BIS CAIR-1 MFM6 |
BCL2-associated athanogene 3 | Genistein results in increased expression of BAG3 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 9529 |
BAG5
BAG-5 |
BCL2-associated athanogene 5 | ESR2 promotes the reaction [Genistein results in decreased expression of BAG5 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 9529 |
BAG5
BAG-5 |
BCL2-associated athanogene 5 | Genistein results in decreased expression of BAG5 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 10409 |
BASP1
CAP-23 CAP23 NAP-22 NAP22 |
brain abundant, membrane attached signal protein 1 | Genistein results in decreased expression of BASP1 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 581 |
BAX
BCL2L4 |
BCL2-associated X protein | arsenic trioxide promotes the reaction [Genistein results in increased expression of BAX protein] |
increases expression
/ increases reaction |
protein |
20219070
|
| D019833 | 581 |
BAX
BCL2L4 |
BCL2-associated X protein | [Calcitriol co-treated with Genistein] results in increased expression of BAX mRNA |
affects cotreatment
/ increases expression |
mRNA |
15955619
|
| D019833 | 581 |
BAX
BCL2L4 |
BCL2-associated X protein | [Genistein co-treated with TNFSF10 protein] results in increased expression of BAX protein |
affects cotreatment
/ increases expression |
protein |
19497411
|
| D019833 | 581 |
BAX
BCL2L4 |
BCL2-associated X protein | Genistein promotes the reaction [arsenic trioxide results in increased expression of BAX protein] |
increases expression
/ increases reaction |
protein |
20219070
|
| D019833 | 581 |
BAX
BCL2L4 |
BCL2-associated X protein | Genistein results in increased expression of BAX protein |
increases expression
|
protein |
20219070
|
| D019833 | 11177 |
BAZ1A
ACF1 WALp1 WCRF180 hACF1 |
bromodomain adjacent to zinc finger domain, 1A | [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of BAZ1A mRNA |
affects cotreatment
/ increases expression |
mRNA |
16963248
|
| D019833 | 11176 |
BAZ2A
TIP5 WALp3 |
bromodomain adjacent to zinc finger domain, 2A | Genistein results in decreased expression of BAZ2A mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 590 |
BCHE
CHE1 CHE2 E1 |
butyrylcholinesterase (EC:3.1.1.8) | Genistein results in increased expression of BCHE mRNA |
increases expression
|
mRNA |
15378649
|
| D019833 | 593 |
BCKDHA
BCKDE1A MSU MSUD1 OVD1A |
branched chain keto acid dehydrogenase E1, alpha polypeptide (EC:1.2.4.4) | ESR1 promotes the reaction [Genistein results in decreased expression of BCKDHA protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 593 |
BCKDHA
BCKDE1A MSU MSUD1 OVD1A |
branched chain keto acid dehydrogenase E1, alpha polypeptide (EC:1.2.4.4) | Genistein results in decreased expression of BCKDHA protein |
decreases expression
|
protein |
20884965
|
| D019833 | 596 |
BCL2
Bcl-2 PPP1R50 |
B-cell CLL/lymphoma 2 | arsenic trioxide promotes the reaction [Genistein results in decreased expression of BCL2 protein] |
decreases expression
/ increases reaction |
protein |
20219070
|
| D019833 | 596 |
BCL2
Bcl-2 PPP1R50 |
B-cell CLL/lymphoma 2 | [Calcitriol co-treated with Genistein] results in decreased expression of BCL2 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
15955619
|
| D019833 | 596 |
BCL2
Bcl-2 PPP1R50 |
B-cell CLL/lymphoma 2 | [Genistein co-treated with arsenic trioxide] results in decreased expression of BCL2 protein |
affects cotreatment
/ decreases expression |
protein |
21078540
|
| D019833 | 596 |
BCL2
Bcl-2 PPP1R50 |
B-cell CLL/lymphoma 2 | [Genistein co-treated with TNFSF10 protein] results in decreased expression of BCL2 protein |
affects cotreatment
/ decreases expression |
protein |
19497411
|
| D019833 | 596 |
BCL2
Bcl-2 PPP1R50 |
B-cell CLL/lymphoma 2 | Genistein inhibits the reaction [Paclitaxel results in increased phosphorylation of BCL2 protein] |
decreases reaction
/ increases phosphorylation |
protein |
15907805
|
| D019833 | 596 |
BCL2
Bcl-2 PPP1R50 |
B-cell CLL/lymphoma 2 | Genistein inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of BCL2 protein] |
decreases expression
/ decreases reaction |
protein |
15288519
|
| D019833 | 596 |
BCL2
Bcl-2 PPP1R50 |
B-cell CLL/lymphoma 2 | Genistein promotes the reaction [arsenic trioxide results in decreased expression of BCL2 protein] |
decreases expression
/ increases reaction |
protein |
20219070
|
| D019833 | 596 |
BCL2
Bcl-2 PPP1R50 |
B-cell CLL/lymphoma 2 | Genistein results in decreased expression of BCL2 protein |
decreases expression
|
protein |
12791511
20219070 21078540 |
| D019833 | 598 |
BCL2L1
BCL-XL/S BCL2L BCLX BCLXL BCLXS Bcl-X PPP1R52 bcl-xL bcl-xS |
BCL2-like 1 | [Genistein co-treated with arsenic trioxide] results in decreased expression of BCL2L1 protein |
affects cotreatment
/ decreases expression |
protein |
21078540
|
| D019833 | 598 |
BCL2L1
BCL-XL/S BCL2L BCLX BCLXL BCLXS Bcl-X PPP1R52 bcl-xL bcl-xS |
BCL2-like 1 | Genistein promotes the reaction [arsenic trioxide results in decreased expression of BCL2L1 protein] |
decreases expression
/ increases reaction |
protein |
18546268
|
| D019833 | 598 |
BCL2L1
BCL-XL/S BCL2L BCLX BCLXL BCLXS Bcl-X PPP1R52 bcl-xL bcl-xS |
BCL2-like 1 | Genistein results in decreased expression of BCL2L1 protein |
decreases expression
|
protein |
12791511
18546268 21078540 |
| D019833 | 632 |
BGLAP
BGP OC OCN |
bone gamma-carboxyglutamate (gla) protein | [Genistein co-treated with ESR1 protein] results in increased expression of BGLAP mRNA |
affects cotreatment
/ increases expression |
mRNA |
19347870
|
| D019833 | 632 |
BGLAP
BGP OC OCN |
bone gamma-carboxyglutamate (gla) protein | [Genistein co-treated with ESR2 protein] results in increased expression of BGLAP mRNA |
affects cotreatment
/ increases expression |
mRNA |
19347870
|
| D019833 | 168620 |
BHLHA15
BHLHB8 MIST1 |
basic helix-loop-helix family, member a15 | Genistein results in increased expression of BHLHA15 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 8553 |
BHLHE40
BHLHB2 DEC1 HLHB2 SHARP-2 STRA13 Stra14 |
basic helix-loop-helix family, member e40 | Genistein results in decreased expression of BHLHE40 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 636 |
BICD1
BICD |
bicaudal D homolog 1 (Drosophila) | Genistein results in increased expression of BICD1 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 637 |
BID
FP497 |
BH3 interacting domain death agonist | [Genistein co-treated with TNFSF10 protein] results in increased cleavage of BID protein |
affects cotreatment
/ increases cleavage |
protein |
19497411
|
| D019833 | 637 |
BID
FP497 |
BH3 interacting domain death agonist | Genistein promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of BID protein] |
increases activity
/ increases cleavage / increases reaction |
protein |
18546268
|
| D019833 | 637 |
BID
FP497 |
BH3 interacting domain death agonist | Genistein results in increased cleavage of and results in increased activity of BID protein |
increases activity
/ increases cleavage |
protein |
18546268
|
| D019833 | 332 |
BIRC5
API4 EPR-1 |
baculoviral IAP repeat containing 5 | Genistein results in decreased expression of BIRC5 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 332 |
BIRC5
API4 EPR-1 |
baculoviral IAP repeat containing 5 | Genistein results in increased expression of BIRC5 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 90427 |
BMF
|
Bcl2 modifying factor | Genistein results in decreased expression of BMF mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 662 |
BNIP1
NIP1 SEC20 TRG-8 |
BCL2/adenovirus E1B 19kDa interacting protein 1 | Genistein results in increased expression of BNIP1 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 665 |
BNIP3L
BNIP3a NIX |
BCL2/adenovirus E1B 19kDa interacting protein 3-like | Genistein results in decreased expression of BNIP3L mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 672 |
BRCA1
BRCAI BRCC1 BROVCA1 IRIS PNCA4 PPP1R53 PSCP RNF53 |
breast cancer 1, early onset | Genistein results in increased expression of BRCA1 mRNA |
increases expression
|
mRNA |
16434996
17266178 |
| D019833 | 672 |
BRCA1
BRCAI BRCC1 BROVCA1 IRIS PNCA4 PPP1R53 PSCP RNF53 |
breast cancer 1, early onset | Genistein results in increased expression of BRCA1 protein |
increases expression
|
protein |
16434996
|
| D019833 | 672 |
BRCA1
BRCAI BRCC1 BROVCA1 IRIS PNCA4 PPP1R53 PSCP RNF53 |
breast cancer 1, early onset | [indole-3-carbinol co-treated with Genistein] results in increased expression of BRCA1 protein |
affects cotreatment
/ increases expression |
protein |
16434996
|
| D019833 | 675 |
BRCA2
BRCC2 BROVCA2 FACD FAD FAD1 FANCB FANCD FANCD1 GLM3 PNCA2 |
breast cancer 2, early onset | Genistein results in increased expression of BRCA2 mRNA |
increases expression
|
mRNA |
16434996
|
| D019833 | 675 |
BRCA2
BRCC2 BROVCA2 FACD FAD FAD1 FANCB FANCD FANCD1 GLM3 PNCA2 |
breast cancer 2, early onset | Genistein results in increased expression of BRCA2 protein |
increases expression
|
protein |
16434996
|
| D019833 | 675 |
BRCA2
BRCC2 BROVCA2 FACD FAD FAD1 FANCB FANCD FANCD1 GLM3 PNCA2 |
breast cancer 2, early onset | [indole-3-carbinol co-treated with Genistein] results in increased expression of BRCA2 protein |
affects cotreatment
/ increases expression |
protein |
16434996
|
| D019833 | 55845 |
BRK1
C3orf10 MDS027 hHBrk1 |
BRICK1, SCAR/WAVE actin-nucleating complex subunit | Genistein results in increased expression of BRK1 mRNA |
increases expression
|
mRNA |
16705744
|
| D019833 | 428592 | Genistein results in increased expression of BRP44L mRNA |
increases expression
|
mRNA |
20884965
|
||
| D019833 | 103993 | [Genistein co-treated with ESR1] results in increased expression of BSP mRNA |
affects cotreatment
/ increases expression |
mRNA |
19347870
|
||
| D019833 | 103993 | [Genistein co-treated with ESR2] results in increased expression of BSP mRNA |
affects cotreatment
/ increases expression |
mRNA |
19347870
|
||
| D019833 | 694 |
BTG1
|
B-cell translocation gene 1, anti-proliferative | Genistein results in decreased expression of BTG1 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 7832 |
BTG2
PC3 TIS21 |
BTG family, member 2 | Genistein results in decreased expression of BTG2 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 10950 |
BTG3
ANA TOB5 TOB55 TOFA |
BTG family, member 3 | Genistein results in decreased methylation of BTG3 promoter |
decreases methylation
|
promoter |
19221000
|
| D019833 | 10950 |
BTG3
ANA TOB5 TOB55 TOFA |
BTG family, member 3 | Genistein results in increased expression of BTG3 mRNA |
increases expression
|
mRNA |
19221000
|
| D019833 | 699 |
BUB1
BUB1A BUB1L hBUB1 |
BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1) | Genistein affects the expression of BUB1 mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 701 |
BUB1B
BUB1beta BUBR1 Bub1A MAD3L MVA1 SSK1 hBUBR1 |
BUB1 mitotic checkpoint serine/threonine kinase B (EC:2.7.11.1) | Genistein affects the expression of BUB1B mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 701 |
BUB1B
BUB1beta BUBR1 Bub1A MAD3L MVA1 SSK1 hBUBR1 |
BUB1 mitotic checkpoint serine/threonine kinase B (EC:2.7.11.1) | Genistein results in increased expression of BUB1B mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 56652 |
C10orf2
ATXN8 IOSCA MTDPS7 PEO PEO1 PEOA3 SANDO SCA8 TWINL |
chromosome 10 open reading frame 2 (EC:3.6.4.12) | Genistein results in increased expression of C10ORF2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 219833 |
C11orf45
|
chromosome 11 open reading frame 45 | Genistein results in increased expression of C11ORF45 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 84419 |
C15orf48
FOAP-11 NMES1 |
chromosome 15 open reading frame 48 | Genistein results in decreased expression of C15ORF48 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 79415 |
C17orf62
|
chromosome 17 open reading frame 62 | Genistein results in increased expression of C17ORF62 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 388722 |
C1orf53
|
chromosome 1 open reading frame 53 | Genistein results in decreased expression of C1ORF53 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 79680 |
C22orf29
BOP |
chromosome 22 open reading frame 29 | Genistein results in increased expression of C22ORF29 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 79919 |
C2orf54
|
chromosome 2 open reading frame 54 | Genistein results in increased expression of C2ORF54 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 718 |
C3
AHUS5 ARMD9 ASP C3a C3b CPAMD1 |
complement component 3 (EC:3.4.21.43) | Genistein results in increased expression of C3 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 100495920 | Genistein results in increased expression of C3ORF21 mRNA |
increases expression
|
mRNA |
23019147
|
||
| D019833 | 50854 |
C6orf48
D6S57 G8 |
chromosome 6 open reading frame 48 | Genistein results in decreased expression of C6ORF48 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 771 |
CA12
CAXII HsT18816 |
carbonic anhydrase XII (EC:4.2.1.1) | Genistein results in increased expression of CA12 mRNA |
increases expression
|
mRNA |
16474171
23019147 |
| D019833 | 760 |
CA2
CA-II CAC CAII Car2 |
carbonic anhydrase II (EC:4.2.1.1) | Genistein results in increased expression of CA2 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 91768 |
CABLES1
CABL1 CABLES HsT2563 IK3-1 |
Cdk5 and Abl enzyme substrate 1 | Genistein results in increased expression of CABLES1 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 8911 |
CACNA1I
Cav3.3 ca(v)3.3 |
calcium channel, voltage-dependent, T type, alpha 1I subunit | Genistein results in increased expression of CACNA1I mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 55450 |
CAMK2N1
PRO1489 RP11-401M16.1 |
calcium/calmodulin-dependent protein kinase II inhibitor 1 | Genistein results in decreased expression of CAMK2N1 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 10645 |
CAMKK2
CAMKK CAMKKB |
calcium/calmodulin-dependent protein kinase kinase 2, beta (EC:2.7.11.17) | Genistein results in decreased expression of CAMKK2 mRNA |
decreases expression
|
mRNA |
15378649
|
| D019833 | 821 |
CANX
CNX IP90 P90 |
calnexin | ESR2 promotes the reaction [Genistein results in increased expression of CANX protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 821 |
CANX
CNX IP90 P90 |
calnexin | Genistein results in increased expression of CANX protein |
increases expression
|
protein |
20884965
|
| D019833 | 823 |
CAPN1
CANP CANP1 CANPL1 muCANP muCL |
calpain 1, (mu/I) large subunit (EC:3.4.22.52) | Genistein results in decreased expression of CAPN1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 6650 |
CAPN15
SOLH |
calpain 15 | Genistein results in increased expression of CAPN15 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 10753 |
CAPN9
GC36 nCL-4 |
calpain 9 (EC:3.4.22.-) | Genistein results in increased expression of CAPN9 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 828 |
CAPS
CAPS1 |
calcyphosine | Genistein results in increased expression of CAPS mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 29775 |
CARD10
BIMP1 CARMA3 |
caspase recruitment domain family, member 10 | Genistein results in increased expression of CARD10 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 833 |
CARS
CARS1 CYSRS MGC:11246 |
cysteinyl-tRNA synthetase (EC:6.1.1.16) | Genistein results in increased expression of CARS mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 843 |
CASP10
ALPS2 FLICE2 MCH4 |
caspase 10, apoptosis-related cysteine peptidase (EC:3.4.22.63) | [Genistein co-treated with trichostatin A] results in increased activity of CASP10 protein |
affects cotreatment
/ increases activity |
protein |
22626855
|
| D019833 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | arsenic trioxide promotes the reaction [Genistein results in increased activity of CASP3 protein] |
increases activity
/ increases reaction |
protein |
20219070
|
| D019833 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | [Genistein co-treated with arsenic trioxide] results in decreased expression of CASP3 protein |
affects cotreatment
/ decreases expression |
protein |
21078540
|
| D019833 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | [Genistein co-treated with TNFSF10 protein] results in increased activity of CASP3 protein |
affects cotreatment
/ increases activity |
protein |
19497411
|
| D019833 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | [Genistein co-treated with trichostatin A] results in increased activity of CASP3 protein |
affects cotreatment
/ increases activity |
protein |
22626855
|
| D019833 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | Genistein inhibits the reaction [benzo(e)pyrene results in increased activity of CASP3 protein] |
decreases reaction
/ increases activity |
protein |
19959636
|
| D019833 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | Genistein promotes the reaction [arsenic trioxide results in increased activity of CASP3 protein] |
increases activity
/ increases reaction |
protein |
18546268
20219070 |
| D019833 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | Genistein results in decreased expression of CASP3 protein |
decreases expression
|
protein |
21078540
|
| D019833 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | Genistein results in increased activity of CASP3 protein |
increases activity
|
protein |
12791511
16924424 17132221 20219070 |
| D019833 | 840 |
CASP7
CASP-7 CMH-1 ICE-LAP3 LICE2 MCH3 |
caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) | Genistein inhibits the reaction [benzo(e)pyrene results in increased activity of CASP7 protein] |
decreases reaction
/ increases activity |
protein |
19959636
|
| D019833 | 841 |
CASP8
ALPS2B CAP4 Casp-8 FLICE MACH MCH5 |
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) | [Genistein co-treated with TNFSF10 protein] results in increased activity of CASP8 protein |
affects cotreatment
/ increases activity |
protein |
19497411
|
| D019833 | 841 |
CASP8
ALPS2B CAP4 Casp-8 FLICE MACH MCH5 |
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) | Genistein promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of CASP8 protein] |
increases activity
/ increases cleavage / increases reaction |
protein |
18546268
|
| D019833 | 9994 |
CASP8AP2
CED-4 FLASH RIP25 |
caspase 8 associated protein 2 | Genistein results in increased expression of CASP8AP2 mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 842 |
CASP9
APAF-3 APAF3 ICE-LAP6 MCH6 PPP1R56 |
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) | [Genistein co-treated with TNFSF10 protein] results in increased activity of CASP9 protein |
affects cotreatment
/ increases activity |
protein |
19497411
|
| D019833 | 842 |
CASP9
APAF-3 APAF3 ICE-LAP6 MCH6 PPP1R56 |
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) | Genistein inhibits the reaction [benzo(e)pyrene results in increased activity of CASP9 protein] |
decreases reaction
/ increases activity |
protein |
19959636
|
| D019833 | 842 |
CASP9
APAF-3 APAF3 ICE-LAP6 MCH6 PPP1R56 |
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) | Genistein promotes the reaction [arsenic trioxide results in increased activity of CASP9 protein] |
increases activity
/ increases reaction |
protein |
20219070
|
| D019833 | 842 |
CASP9
APAF-3 APAF3 ICE-LAP6 MCH6 PPP1R56 |
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) | Genistein results in increased activity of CASP9 protein |
increases activity
|
protein |
20219070
|
| D019833 | 863 |
CBFA2T3
ETO2 MTG16 MTGR2 ZMYND4 |
core-binding factor, runt domain, alpha subunit 2; translocated to, 3 | Genistein results in increased expression of CBFA2T3 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 873 |
CBR1
CBR SDR21C1 hCBR1 |
carbonyl reductase 1 (EC:1.1.1.189 1.1.1.197 1.1.1.184) | Genistein results in increased expression of CBR1 mRNA |
increases expression
|
mRNA |
16705744
|
| D019833 | 23468 |
CBX5
HP1 HP1A |
chromobox homolog 5 | ESR2 promotes the reaction [Genistein results in increased expression of CBX5 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 23468 |
CBX5
HP1 HP1A |
chromobox homolog 5 | Genistein results in increased expression of CBX5 protein |
increases expression
|
protein |
20884965
|
| D019833 | 23466 |
CBX6
|
chromobox homolog 6 | Genistein results in decreased expression of CBX6 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 23466 |
CBX6
|
chromobox homolog 6 | Genistein results in increased expression of CBX6 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 55246 |
CCDC25
|
coiled-coil domain containing 25 | ESR1 promotes the reaction [Genistein results in increased expression of CCDC25 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 55246 |
CCDC25
|
coiled-coil domain containing 25 | Genistein results in increased expression of CCDC25 protein |
increases expression
|
protein |
20884965
|
| D019833 | 26112 |
CCDC69
|
coiled-coil domain containing 69 | Genistein results in increased expression of CCDC69 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 79080 |
CCDC86
|
coiled-coil domain containing 86 | Genistein results in increased expression of CCDC86 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 6347 |
CCL2
GDCF-2 HC11 HSMCR30 MCAF MCP-1 MCP1 SCYA2 SMC-CF |
chemokine (C-C motif) ligand 2 | Genistein inhibits the reaction [LEP protein results in increased expression of CCL2] |
decreases reaction
/ increases expression |
11342529
|
|
| D019833 | 6347 |
CCL2
GDCF-2 HC11 HSMCR30 MCAF MCP-1 MCP1 SCYA2 SMC-CF |
chemokine (C-C motif) ligand 2 | Genistein results in decreased secretion of CCL2 protein |
decreases secretion
|
protein |
20816778
|
| D019833 | 6351 |
CCL4
ACT2 AT744.1 G-26 HC21 LAG-1 LAG1 MIP-1-beta MIP1B MIP1B1 SCYA2 SCYA4 |
chemokine (C-C motif) ligand 4 | Genistein results in decreased expression of CCL4 mRNA |
decreases expression
|
mRNA |
15256057
|
| D019833 | 890 |
CCNA2
CCN1 CCNA |
cyclin A2 | Genistein affects the expression of CCNA2 mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 890 |
CCNA2
CCN1 CCNA |
cyclin A2 | Genistein results in decreased expression of CCNA2 |
decreases expression
|
21161820
|
|
| D019833 | 890 |
CCNA2
CCN1 CCNA |
cyclin A2 | Genistein results in decreased expression of CCNA2 mRNA |
decreases expression
|
mRNA |
16865672
|
| D019833 | 890 |
CCNA2
CCN1 CCNA |
cyclin A2 | Genistein results in increased expression of CCNA2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 891 |
CCNB1
CCNB |
cyclin B1 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of CCNB1 protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 891 |
CCNB1
CCNB |
cyclin B1 | Caffeine inhibits the reaction [Genistein results in increased expression of CCNB1 protein] |
decreases reaction
/ increases expression |
protein |
19038232
|
| D019833 | 891 |
CCNB1
CCNB |
cyclin B1 | Genistein affects the expression of CCNB1 mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 891 |
CCNB1
CCNB |
cyclin B1 | Genistein affects the expression of CCNB1 protein |
affects expression
|
protein |
10601582
|
| D019833 | 891 |
CCNB1
CCNB |
cyclin B1 | Genistein results in increased expression of CCNB1 protein |
increases expression
|
protein |
19038232
|
| D019833 | 891 |
CCNB1
CCNB |
cyclin B1 | U 0126 inhibits the reaction [Genistein results in increased phosphorylation of CCNB1 protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 9133 |
CCNB2
HsT17299 |
cyclin B2 | Genistein affects the expression of CCNB2 mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 9133 |
CCNB2
HsT17299 |
cyclin B2 | Genistein results in decreased expression of CCNB2 mRNA |
decreases expression
|
mRNA |
16865672
|
| D019833 | 9133 |
CCNB2
HsT17299 |
cyclin B2 | Genistein results in increased expression of CCNB2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 595 |
CCND1
BCL1 D11S287E PRAD1 U21B31 |
cyclin D1 | [Calcitriol co-treated with Genistein] results in decreased expression of CCND1 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
15955619
|
| D019833 | 595 |
CCND1
BCL1 D11S287E PRAD1 U21B31 |
cyclin D1 | [Genistein co-treated with arsenic trioxide] results in decreased expression of CCND1 protein |
affects cotreatment
/ decreases expression |
protein |
21078540
|
| D019833 | 595 |
CCND1
BCL1 D11S287E PRAD1 U21B31 |
cyclin D1 | Genistein inhibits the reaction [bisphenol A results in increased expression of CCND1] |
decreases reaction
/ increases expression |
23229410
|
|
| D019833 | 595 |
CCND1
BCL1 D11S287E PRAD1 U21B31 |
cyclin D1 | Genistein inhibits the reaction [Estradiol results in increased expression of CCND1] |
decreases reaction
/ increases expression |
23229410
|
|
| D019833 | 595 |
CCND1
BCL1 D11S287E PRAD1 U21B31 |
cyclin D1 | Genistein results in decreased expression of CCND1 mRNA |
decreases expression
|
mRNA |
15955619
|
| D019833 | 595 |
CCND1
BCL1 D11S287E PRAD1 U21B31 |
cyclin D1 | Genistein results in decreased expression of CCND1 protein |
decreases expression
|
protein |
21078540
|
| D019833 | 595 |
CCND1
BCL1 D11S287E PRAD1 U21B31 |
cyclin D1 | Genistein results in increased expression of CCND1 mRNA |
increases expression
|
mRNA |
17266178
19800779 23524099 |
| D019833 | 595 |
CCND1
BCL1 D11S287E PRAD1 U21B31 |
cyclin D1 | Genistein results in increased expression of CCND1 protein |
increases expression
|
protein |
15829497
17051425 |
| D019833 | 595 |
CCND1
BCL1 D11S287E PRAD1 U21B31 |
cyclin D1 | lycopene inhibits the reaction [Genistein results in increased expression of CCND1 protein] |
decreases reaction
/ increases expression |
protein |
17051425
|
| D019833 | 894 |
CCND2
KIAK0002 |
cyclin D2 | Genistein results in increased expression of CCND2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 960 |
CD44
CDW44 CSPG8 ECMR-III HCELL HUTCH-I IN LHR MC56 MDU2 MDU3 MIC4 Pgp1 |
CD44 molecule (Indian blood group) | Genistein results in decreased expression of CD44 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 960 |
CD44
CDW44 CSPG8 ECMR-III HCELL HUTCH-I IN LHR MC56 MDU2 MDU3 MIC4 Pgp1 |
CD44 molecule (Indian blood group) | Genistein results in increased expression of CD44 mRNA |
increases expression
|
mRNA |
20706672
|
| D019833 | 965 |
CD58
LFA-3 LFA3 ag3 |
CD58 molecule | Genistein results in increased expression of CD58 mRNA |
increases expression
|
mRNA |
16705744
|
| D019833 | 3732 |
CD82
4F9 C33 GR15 IA4 KAI1 R2 SAR2 ST6 TSPAN27 |
CD82 molecule | Genistein results in increased expression of CD82 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 928 |
CD9
BTCC-1 DRAP-27 MIC3 MRP-1 TSPAN-29 TSPAN29 |
CD9 molecule | ESR2 promotes the reaction [Genistein results in increased expression of CD9 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 928 |
CD9
BTCC-1 DRAP-27 MIC3 MRP-1 TSPAN-29 TSPAN29 |
CD9 molecule | Genistein results in increased expression of CD9 protein |
increases expression
|
protein |
20884965
|
| D019833 | 976 |
CD97
TM7LN1 |
CD97 molecule | Genistein results in decreased expression of CD97 mRNA |
decreases expression
|
mRNA |
21738342
|
| D019833 | 991 |
CDC20
CDC20A bA276H19.3 p55CDC |
cell division cycle 20 | Genistein affects the expression of CDC20 mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 991 |
CDC20
CDC20A bA276H19.3 p55CDC |
cell division cycle 20 | Genistein results in increased expression of CDC20 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 994 |
CDC25B
|
cell division cycle 25B (EC:3.1.3.48) | Genistein results in decreased expression of CDC25B mRNA |
decreases expression
|
mRNA |
16865672
|
| D019833 | 995 |
CDC25C
CDC25 PPP1R60 |
cell division cycle 25C (EC:3.1.3.48) | Genistein results in decreased expression of CDC25C mRNA |
decreases expression
|
mRNA |
16865672
|
| D019833 | 11135 |
CDC42EP1
BORG5 CEP1 MSE55 |
CDC42 effector protein (Rho GTPase binding) 1 | Genistein results in increased expression of CDC42EP1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 8318 |
CDC45
CDC45L CDC45L2 PORC-PI-1 |
cell division cycle 45 | Genistein results in increased expression of CDC45 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 990 |
CDC6
CDC18L HsCDC18 HsCDC6 |
cell division cycle 6 | Genistein results in increased expression of CDC6 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 113130 |
CDCA5
SORORIN |
cell division cycle associated 5 | Genistein affects the expression of CDCA5 mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 1000 |
CDH2
CD325 CDHN CDw325 NCAD |
cadherin 2, type 1, N-cadherin (neuronal) | Genistein results in increased expression of CDH2 protein |
increases expression
|
protein |
16149052
|
| D019833 | 983 |
CDK1
CDC2 CDC28A P34CDC2 |
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of CDK1 protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 983 |
CDK1
CDC2 CDC28A P34CDC2 |
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) | Caffeine inhibits the reaction [Genistein results in increased phosphorylation of CDK1 protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 983 |
CDK1
CDC2 CDC28A P34CDC2 |
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) | Genistein affects the expression of CDK1 mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 983 |
CDK1
CDC2 CDC28A P34CDC2 |
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) | Genistein results in decreased phosphorylation of CDK1 protein |
decreases phosphorylation
|
protein |
10601582
|
| D019833 | 983 |
CDK1
CDC2 CDC28A P34CDC2 |
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) | Genistein results in increased expression of CDK1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 983 |
CDK1
CDC2 CDC28A P34CDC2 |
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) | Genistein results in increased phosphorylation of and results in decreased activity of CDK1 protein |
decreases activity
/ increases phosphorylation |
protein |
11322924
|
| D019833 | 983 |
CDK1
CDC2 CDC28A P34CDC2 |
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) | Genistein results in increased phosphorylation of CDK1 protein |
increases phosphorylation
|
protein |
19038232
|
| D019833 | 983 |
CDK1
CDC2 CDC28A P34CDC2 |
cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) | U 0126 inhibits the reaction [Genistein results in increased phosphorylation of CDK1 protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 1017 |
CDK2
p33(CDK2) |
cyclin-dependent kinase 2 (EC:2.7.11.22) | Genistein results in increased expression of CDK2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 10263 |
CDK2AP2
DOC-1R p14 |
cyclin-dependent kinase 2 associated protein 2 | Genistein results in decreased expression of CDK2AP2 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 1019 |
CDK4
CMM3 PSK-J3 |
cyclin-dependent kinase 4 (EC:2.7.11.22) | Genistein results in decreased activity of CDK4 protein |
decreases activity
|
protein |
21161820
|
| D019833 | 1020 |
CDK5
PSSALRE |
cyclin-dependent kinase 5 (EC:2.7.11.22) | Genistein results in increased expression of CDK5 protein |
increases expression
|
protein |
16149052
|
| D019833 | 1024 |
CDK8
K35 |
cyclin-dependent kinase 8 (EC:2.7.11.23 2.7.11.22) | Genistein results in increased expression of CDK8 mRNA |
increases expression
|
mRNA |
15378649
|
| D019833 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of CDKN1A protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | [Calcitriol co-treated with Genistein] results in increased expression of CDKN1A mRNA |
affects cotreatment
/ increases expression |
mRNA |
15955619
|
| D019833 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | ESR2 affects the reaction [Genistein results in increased expression of CDKN1A] |
affects reaction
/ increases expression |
21161820
|
|
| D019833 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | [Fluorouracil co-treated with Genistein] results in increased expression of CDKN1A mRNA |
affects cotreatment
/ increases expression |
mRNA |
15896711
|
| D019833 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | Genistein inhibits the reaction [bisphenol A results in decreased expression of CDKN1A] |
decreases expression
/ decreases reaction |
23229410
|
|
| D019833 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | Genistein inhibits the reaction [Estradiol results in decreased expression of CDKN1A] |
decreases expression
/ decreases reaction |
23229410
|
|
| D019833 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | Genistein results in decreased expression of CDKN1A mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | Genistein results in decreased expression of CDKN1A protein |
decreases expression
|
protein |
17051425
|
| D019833 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | Genistein results in increased expression of CDKN1A |
increases expression
|
21161820
|
|
| D019833 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | Genistein results in increased expression of CDKN1A mRNA |
increases expression
|
mRNA |
16865672
|
| D019833 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | Genistein results in increased expression of CDKN1A protein |
increases expression
|
protein |
11322924
11790449 12111696 16149052 19038232 |
| D019833 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | U 0126 inhibits the reaction [Genistein results in increased phosphorylation of CDKN1A protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 1027 |
CDKN1B
CDKN4 KIP1 MEN1B MEN4 P27KIP1 |
cyclin-dependent kinase inhibitor 1B (p27, Kip1) | Genistein results in increased expression of CDKN1B protein |
increases expression
|
protein |
15829497
|
| D019833 | 1028 |
CDKN1C
BWCR BWS KIP2 WBS p57 p57Kip2 |
cyclin-dependent kinase inhibitor 1C (p57, Kip2) | Genistein results in decreased expression of CDKN1C mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 1031 |
CDKN2C
INK4C p18 p18-INK4C |
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | Genistein results in decreased expression of CDKN2C mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 1033 |
CDKN3
CDI1 CIP2 KAP KAP1 |
cyclin-dependent kinase inhibitor 3 (EC:3.1.3.16 3.1.3.48) | Genistein results in decreased expression of CDKN3 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 81620 |
CDT1
DUP RIS2 |
chromatin licensing and DNA replication factor 1 | Genistein results in increased expression of CDT1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 1051 |
CEBPB
C/EBP-beta CRP2 IL6DBP LAP LIP NF-IL6 TCF5 |
CCAAT/enhancer binding protein (C/EBP), beta | Genistein results in increased expression of CEBPB mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 1052 |
CEBPD
C/EBP-delta CELF CRP3 NF-IL6-beta |
CCAAT/enhancer binding protein (C/EBP), delta | Genistein results in decreased expression of CEBPD mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 1052 |
CEBPD
C/EBP-delta CELF CRP3 NF-IL6-beta |
CCAAT/enhancer binding protein (C/EBP), delta | Genistein results in increased expression of CEBPD mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 1952 |
CELSR2
CDHF10 EGFL2 Flamingo1 MEGF3 |
cadherin, EGF LAG seven-pass G-type receptor 2 | Genistein results in increased expression of CELSR2 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 1058 |
CENPA
CENP-A CenH3 |
centromere protein A | Genistein results in increased expression of CENPA mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 1062 |
CENPE
CENP-E KIF10 PPP1R61 |
centromere protein E, 312kDa | Genistein affects the expression of CENPE mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 1063 |
CENPF
CENF PRO1779 hcp-1 |
centromere protein F, 350/400kDa | Genistein affects the expression of CENPF mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 1063 |
CENPF
CENF PRO1779 hcp-1 |
centromere protein F, 350/400kDa | Genistein results in increased expression of CENPF mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 55835 |
CENPJ
BM032 CENP-J CPAP LAP LIP1 MCPH6 SASS4 SCKL4 Sas-4 |
centromere protein J | Genistein results in increased expression of CENPJ mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 55839 |
CENPN
BM039 C16orf60 CENP-N ICEN32 |
centromere protein N | Genistein results in increased expression of CENPN mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides] |
affects cotreatment
/ decreases reaction / increases activity / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]] |
affects cotreatment
/ decreases reaction / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | 5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]] |
affects cotreatment
/ decreases reaction / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | 6-hydroxy-10-chlorobenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]] |
affects cotreatment
/ decreases reaction / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] |
affects cotreatment
/ decreases reaction / increases reaction / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] |
affects cotreatment
/ decreases reaction / increases reaction / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | Brefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] |
affects cotreatment
/ decreases reaction / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | Brefeldin A inhibits the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] |
affects cotreatment
/ decreases reaction / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides] |
affects cotreatment
/ decreases reaction / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | [Colforsin co-treated with Genistein] results in increased activity of CFTR protein |
affects cotreatment
/ increases activity |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | [[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides |
affects cotreatment
/ increases activity / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | fenamic acid inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides] |
affects cotreatment
/ decreases reaction / increases activity / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | geldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] |
affects cotreatment
/ decreases reaction / increases reaction / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | geldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] |
affects cotreatment
/ decreases reaction / increases reaction / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | Genistein affects the localization of CFTR protein mutant form |
affects localization
|
protein |
15191910
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | Genistein promotes the reaction [CFTR protein affects the export of Chlorides] |
affects export
/ increases reaction |
protein |
12914781
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | Genistein results in increased activity of CFTR protein |
increases activity
|
protein |
12914781
15163550 15880796 |
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | Genistein results in increased activity of CFTR protein mutant form |
increases activity
|
protein |
15163550
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | Glyburide inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides] |
affects cotreatment
/ decreases reaction / increases activity / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]] |
affects cotreatment
/ decreases reaction / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | Thapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] |
affects cotreatment
/ decreases reaction / increases reaction / increases transport |
protein |
18230692
|
| D019833 | 1080 |
CFTR
ABC35 ABCC7 CF CFTR/MRP MRP7 TNR-CFTR dJ760C5.1 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) | Thapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] |
affects cotreatment
/ decreases reaction / increases reaction / increases transport |
protein |
18230692
|
| D019833 | 494143 |
CHAC2
|
ChaC, cation transport regulator homolog 2 (E. coli) | Genistein results in increased expression of CHAC2 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 10036 |
CHAF1A
CAF-1 CAF1 CAF1B CAF1P150 P150 |
chromatin assembly factor 1, subunit A (p150) | Genistein results in decreased expression of CHAF1A mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 118487 |
CHCHD1
C10orf34 C2360 MRP-S37 |
coiled-coil-helix-coiled-coil-helix domain containing 1 | ESR1 promotes the reaction [Genistein results in decreased expression of CHCHD1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 118487 |
CHCHD1
C10orf34 C2360 MRP-S37 |
coiled-coil-helix-coiled-coil-helix domain containing 1 | Genistein results in decreased expression of CHCHD1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 1111 |
CHEK1
CHK1 |
checkpoint kinase 1 (EC:2.7.11.1) | Genistein results in increased expression of CHEK1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 11200 |
CHEK2
CDS1 CHK2 HuCds1 LFS2 PP1425 RAD53 hCds1 |
checkpoint kinase 2 (EC:2.7.11.1) | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of CHEK2 protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 11200 |
CHEK2
CDS1 CHK2 HuCds1 LFS2 PP1425 RAD53 hCds1 |
checkpoint kinase 2 (EC:2.7.11.1) | Caffeine inhibits the reaction [Genistein results in increased phosphorylation of CHEK2 protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 11200 |
CHEK2
CDS1 CHK2 HuCds1 LFS2 PP1425 RAD53 hCds1 |
checkpoint kinase 2 (EC:2.7.11.1) | Genistein results in increased phosphorylation of CHEK2 protein |
increases phosphorylation
|
protein |
19038232
|
| D019833 | 11200 |
CHEK2
CDS1 CHK2 HuCds1 LFS2 PP1425 RAD53 hCds1 |
checkpoint kinase 2 (EC:2.7.11.1) | U 0126 inhibits the reaction [Genistein results in increased phosphorylation of CHEK2 protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 25978 |
CHMP2B
ALS17 CHMP2.5 DMT1 VPS2-2 VPS2B |
charged multivesicular body protein 2B | ESR1 promotes the reaction [Genistein results in decreased expression of CHMP2B protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 25978 |
CHMP2B
ALS17 CHMP2.5 DMT1 VPS2-2 VPS2B |
charged multivesicular body protein 2B | Genistein results in decreased expression of CHMP2B protein |
decreases expression
|
protein |
20884965
|
| D019833 | 1124 |
CHN2
ARHGAP3 BCH CHN2-3 RHOGAP3 |
chimerin 2 | Genistein results in decreased expression of CHN2 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 22856 |
CHSY1
CHSY CSS1 ChSy-1 TPBS |
chondroitin sulfate synthase 1 (EC:2.4.1.175 2.4.1.226) | Genistein results in increased expression of CHSY1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 8483 |
CILP
CILP-1 HsT18872 |
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | Genistein results in increased expression of CILP mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 1154 |
CISH
BACTS2 CIS CIS-1 G18 SOCS |
cytokine inducible SH2-containing protein | Genistein results in increased expression of CISH mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 11113 |
CIT
CRIK STK21 |
citron (rho-interacting, serine/threonine kinase 21) (EC:2.7.11.1) | Genistein affects the expression of CIT mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 10370 |
CITED2
ASD8 MRG-1 MRG1 P35SRJ VSD2 |
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | Genistein results in increased expression of CITED2 mRNA |
increases expression
|
mRNA |
11331657
|
| D019833 | 1152 |
CKB
B-CK CKBB |
creatine kinase, brain (EC:2.7.3.2) | Genistein results in increased activity of CKB protein |
increases activity
|
protein |
16621514
|
| D019833 | 1152 |
CKB
B-CK CKBB |
creatine kinase, brain (EC:2.7.3.2) | Genistein results in increased expression of CKB mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 1152 |
CKB
B-CK CKBB |
creatine kinase, brain (EC:2.7.3.2) | Glucose inhibits the reaction [Genistein results in increased activity of CKB protein] |
decreases reaction
/ increases activity |
protein |
16621514
|
| D019833 | 1163 |
CKS1B
CKS1 PNAS-16 PNAS-18 ckshs1 |
CDC28 protein kinase regulatory subunit 1B | Genistein results in increased expression of CKS1B mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 9076 |
CLDN1
CLD1 ILVASC SEMP1 |
claudin 1 | ESR2 promotes the reaction [Genistein results in increased expression of CLDN1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 9076 |
CLDN1
CLD1 ILVASC SEMP1 |
claudin 1 | Genistein results in increased expression of CLDN1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 9076 |
CLDN1
CLD1 ILVASC SEMP1 |
claudin 1 | Genistein results in increased expression of CLDN1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 10686 |
CLDN16
HOMG3 PCLN1 |
claudin 16 | Genistein results in decreased expression of CLDN16 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 1364 |
CLDN4
CPE-R CPER CPETR CPETR1 WBSCR8 hCPE-R |
claudin 4 | Genistein results in decreased expression of CLDN4 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 54102 |
CLIC6
CLIC1L |
chloride intracellular channel 6 | Genistein results in increased expression of CLIC6 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 1209 |
CLPTM1
|
cleft lip and palate associated transmembrane protein 1 | Genistein results in decreased expression of CLPTM1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 23277 |
CLUH
CLU1 KIAA0664 |
clustered mitochondria (cluA/CLU1) homolog | Genistein results in increased expression of CLUH mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 112616 |
CMTM7
CKLFSF7 |
CKLF-like MARVEL transmembrane domain containing 7 | Genistein results in increased expression of CMTM7 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 84518 |
CNFN
PLAC8L2 |
cornifelin | Genistein results in decreased expression of CNFN mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 1264 |
CNN1
SMCC Sm-Calp |
calponin 1, basic, smooth muscle | Genistein results in decreased expression of CNN1 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 1265 |
CNN2
|
calponin 2 | ESR2 promotes the reaction [Genistein results in decreased expression of CNN2 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 1265 |
CNN2
|
calponin 2 | Genistein results in decreased expression of CNN2 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 10330 |
CNPY2
HP10390 MSAP TMEM4 ZSIG9 |
canopy FGF signaling regulator 2 | ESR2 promotes the reaction [Genistein results in increased expression of CNPY2 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 10330 |
CNPY2
HP10390 MSAP TMEM4 ZSIG9 |
canopy FGF signaling regulator 2 | Genistein results in increased expression of CNPY2 protein |
increases expression
|
protein |
20884965
|
| D019833 | 1303 |
COL12A1
BA209D8.1 COL12A1L DJ234P15.1 |
collagen, type XII, alpha 1 | Genistein results in increased expression of COL12A1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 80781 |
COL18A1
KNO KNO1 KS |
collagen, type XVIII, alpha 1 | Genistein results in decreased expression of COL18A1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 80781 |
COL18A1
KNO KNO1 KS |
collagen, type XVIII, alpha 1 | Genistein results in increased expression of COL18A1 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 1291 |
COL6A1
OPLL |
collagen, type VI, alpha 1 | Genistein results in increased expression of COL6A1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 1312 |
COMT
|
catechol-O-methyltransferase (EC:2.1.1.6) | fulvestrant inhibits the reaction [Genistein results in decreased expression of COMT mRNA] |
decreases expression
/ decreases reaction |
mRNA |
18192686
18497090 |
| D019833 | 1312 |
COMT
|
catechol-O-methyltransferase (EC:2.1.1.6) | Genistein inhibits the reaction [COMT protein results in increased methylation of 4-hydroxyestradiol] |
decreases reaction
/ increases methylation |
protein |
18192686
|
| D019833 | 1312 |
COMT
|
catechol-O-methyltransferase (EC:2.1.1.6) | Genistein results in decreased activity of COMT protein |
decreases activity
|
protein |
18192686
18497090 |
| D019833 | 1312 |
COMT
|
catechol-O-methyltransferase (EC:2.1.1.6) | Genistein results in decreased expression of COMT mRNA |
decreases expression
|
mRNA |
18192686
18497090 |
| D019833 | 118881 |
COMTD1
|
catechol-O-methyltransferase domain containing 1 | ESR2 promotes the reaction [Genistein results in increased expression of COMTD1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 118881 |
COMTD1
|
catechol-O-methyltransferase domain containing 1 | Genistein results in increased expression of COMTD1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 23603 |
CORO1C
HCRNN4 |
coronin, actin binding protein, 1C | Genistein results in increased expression of CORO1C mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 23406 |
COTL1
CLP |
coactosin-like 1 (Dictyostelium) | ESR2 promotes the reaction [Genistein results in decreased expression of COTL1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 23406 |
COTL1
CLP |
coactosin-like 1 (Dictyostelium) | Genistein results in decreased expression of COTL1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 4512 |
COX1
COI MTCO1 MT-CO1 |
cytochrome c oxidase subunit I | Genistein results in increased expression of COX1 mRNA |
increases expression
|
mRNA |
20706672
|
| D019833 | 9167 |
COX7A2L
COX7AR COX7RP EB1 SIG81 |
cytochrome c oxidase subunit VIIa polypeptide 2 like | ESR2 promotes the reaction [Genistein results in decreased expression of COX7A2L protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 9167 |
COX7A2L
COX7AR COX7RP EB1 SIG81 |
cytochrome c oxidase subunit VIIa polypeptide 2 like | Genistein results in decreased expression of COX7A2L protein |
decreases expression
|
protein |
20884965
|
| D019833 | 9167 |
COX7A2L
COX7AR COX7RP EB1 SIG81 |
cytochrome c oxidase subunit VIIa polypeptide 2 like | Genistein results in increased expression of COX7A2L mRNA |
increases expression
|
mRNA |
17266178
|
| D019833 | 1357 |
CPA1
CPA |
carboxypeptidase A1 (pancreatic) (EC:3.4.17.1) | Genistein results in decreased expression of CPA1 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 1374 |
CPT1A
CPT1 CPT1-L L-CPT1 |
carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21) | [Genistein co-treated with Carnitine] results in increased expression of CPT1A protein |
affects cotreatment
/ increases expression |
protein |
16362726
|
| D019833 | 1374 |
CPT1A
CPT1 CPT1-L L-CPT1 |
carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21) | Genistein results in increased expression of CPT1A mRNA |
increases expression
|
mRNA |
16362726
|
| D019833 | 1396 |
CRIP1
CRHP CRIP CRP-1 CRP1 |
cysteine-rich protein 1 (intestinal) | ESR2 promotes the reaction [Genistein results in increased expression of CRIP1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 1396 |
CRIP1
CRHP CRIP CRP-1 CRP1 |
cysteine-rich protein 1 (intestinal) | Genistein results in increased expression of CRIP1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 83690 |
CRISPLD1
CRISP-10 CRISP10 LCRISP1 |
cysteine-rich secretory protein LCCL domain containing 1 | Genistein results in increased expression of CRISPLD1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 1401 |
CRP
PTX1 |
C-reactive protein, pentraxin-related | [Genistein co-treated with daidzein] results in decreased expression of CRP protein |
affects cotreatment
/ decreases expression |
protein |
16332659
|
| D019833 | 445748 | Genistein results in decreased expression of CSEN mRNA |
decreases expression
|
mRNA |
18847459
|
||
| D019833 | 1465 |
CSRP1
CRP CRP1 CSRP CYRP D1S181E |
cysteine and glycine-rich protein 1 | ESR2 promotes the reaction [Genistein results in decreased expression of CSRP1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 1465 |
CSRP1
CRP CRP1 CSRP CYRP D1S181E |
cysteine and glycine-rich protein 1 | Genistein results in decreased expression of CSRP1 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 1465 |
CSRP1
CRP CRP1 CSRP CYRP D1S181E |
cysteine and glycine-rich protein 1 | Genistein results in decreased expression of CSRP1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 57325 |
CSRP2BP
ATAC2 CRP2BP KAT14 PRO1194 dJ717M23.1 |
CSRP2 binding protein | Genistein results in increased expression of CSRP2BP mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 1475 |
CSTA
AREI STF1 STFA |
cystatin A (stefin A) | Genistein results in increased expression of CSTA mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 1488 |
CTBP2
|
C-terminal binding protein 2 | Genistein results in increased expression of CTBP2 mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 1490 |
CTGF
CCN2 HCS24 IGFBP8 NOV2 |
connective tissue growth factor | Genistein results in decreased expression of CTGF mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 1501 |
CTNND2
GT24 NPRAP |
catenin (cadherin-associated protein), delta 2 | Genistein results in increased expression of CTNND2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 1503 |
CTPS1
CTPS |
CTP synthase 1 (EC:6.3.4.2) | Genistein results in increased expression of CTPS1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 1075 |
CTSC
CPPI DPP-I DPP1 DPPI HMS JP JPD PALS PDON1 PLS |
cathepsin C (EC:3.4.14.1) | Genistein results in increased expression of CTSC mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 1509 |
CTSD
CLN10 CPSD |
cathepsin D (EC:3.4.23.5) | Genistein results in increased expression of CTSD mRNA |
increases expression
|
mRNA |
15090535
|
| D019833 | 8453 |
CUL2
|
cullin 2 | Genistein results in increased expression of CUL2 mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 51596 |
CUTA
ACHAP C6orf82 |
cutA divalent cation tolerance homolog (E. coli) | Genistein results in decreased expression of CUTA mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 1523 |
CUX1
CASP CDP CDP/Cut CDP1 COY1 CUTL1 CUX Clox Cux/CDP GOLIM6 Nbla10317 p100 p110 p200 p75 |
cut-like homeobox 1 | Genistein results in increased expression of CUX1 mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 6387 |
CXCL12
IRH PBSF SCYB12 SDF1 TLSF TPAR1 SDF1A SDF1B |
chemokine (C-X-C motif) ligand 12 | bisphenol A inhibits the reaction [Genistein results in increased expression of CXCL12 mRNA] |
decreases reaction
/ increases expression |
mRNA |
22549810
|
| D019833 | 6387 |
CXCL12
IRH PBSF SCYB12 SDF1 TLSF TPAR1 SDF1A SDF1B |
chemokine (C-X-C motif) ligand 12 | bisphenol A inhibits the reaction [Genistein results in increased expression of CXCL12 protein] |
decreases reaction
/ increases expression |
protein |
22549810
|
| D019833 | 6387 |
CXCL12
IRH PBSF SCYB12 SDF1 TLSF TPAR1 SDF1A SDF1B |
chemokine (C-X-C motif) ligand 12 | CXCL12 mRNA affects the susceptibility to Genistein |
affects response to substance
|
mRNA |
22549810
|
| D019833 | 6387 |
CXCL12
IRH PBSF SCYB12 SDF1 TLSF TPAR1 SDF1A SDF1B |
chemokine (C-X-C motif) ligand 12 | fulvestrant inhibits the reaction [Genistein results in increased expression of CXCL12 mRNA] |
decreases reaction
/ increases expression |
mRNA |
22549810
|
| D019833 | 6387 |
CXCL12
IRH PBSF SCYB12 SDF1 TLSF TPAR1 SDF1A SDF1B |
chemokine (C-X-C motif) ligand 12 | fulvestrant inhibits the reaction [Genistein results in increased expression of CXCL12 protein] |
decreases reaction
/ increases expression |
protein |
22549810
|
| D019833 | 6387 |
CXCL12
IRH PBSF SCYB12 SDF1 TLSF TPAR1 SDF1A SDF1B |
chemokine (C-X-C motif) ligand 12 | Genistein results in increased expression of CXCL12 mRNA |
increases expression
|
mRNA |
22549810
|
| D019833 | 6387 |
CXCL12
IRH PBSF SCYB12 SDF1 TLSF TPAR1 SDF1A SDF1B |
chemokine (C-X-C motif) ligand 12 | Genistein results in increased expression of CXCL12 protein |
increases expression
|
protein |
22549810
|
| D019833 | 6387 |
CXCL12
IRH PBSF SCYB12 SDF1 TLSF TPAR1 SDF1A SDF1B |
chemokine (C-X-C motif) ligand 12 | Genistein results in increased secretion of CXCL12 protein |
increases secretion
|
protein |
20549624
|
| D019833 | 9547 |
CXCL14
BMAC BRAK KEC KS1 MIP-2g MIP2G NJAC SCYB14 |
chemokine (C-X-C motif) ligand 14 | Genistein results in decreased expression of CXCL14 mRNA |
decreases expression
|
mRNA |
15256057
|
| D019833 | 7852 |
CXCR4
CD184 D2S201E FB22 HM89 HSY3RR LAP3 LCR1 LESTR NPY3R NPYR NPYRL NPYY3R WHIM |
chemokine (C-X-C motif) receptor 4 | CXCR4 protein results in decreased susceptibility to Genistein |
decreases response to substance
|
protein |
22549810
|
| D019833 | 1528 |
CYB5A
CYB5 MCB5 |
cytochrome b5 type A (microsomal) | ESR2 promotes the reaction [Genistein results in decreased expression of CYB5A protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 1528 |
CYB5A
CYB5 MCB5 |
cytochrome b5 type A (microsomal) | Genistein results in decreased expression of CYB5A protein |
decreases expression
|
protein |
20884965
|
| D019833 | 1535 |
CYBA
p22-PHOX |
cytochrome b-245, alpha polypeptide | Genistein results in decreased expression of CYBA mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 54205 |
CYCS
CYC HCS THC4 |
cytochrome c, somatic | fulvestrant inhibits the reaction [Genistein affects the localization of CYCS protein] |
affects localization
/ decreases reaction |
protein |
16924424
|
| D019833 | 54205 |
CYCS
CYC HCS THC4 |
cytochrome c, somatic | Genistein affects the localization of CYCS protein |
affects localization
|
protein |
16924424
|
| D019833 | 114757 |
CYGB
HGB STAP |
cytoglobin | Genistein results in decreased expression of CYGB mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 1540 |
CYLD
BRSS CDMT CYLD1 CYLDI EAC MFT MFT1 SBS TEM USPL2 |
cylindromatosis (turban tumor syndrome) (EC:3.4.19.12) | Genistein inhibits the reaction [HIST3H3 protein modified form binds to CYLD promoter] |
affects binding
/ decreases reaction |
promoter |
18431742
|
| D019833 | 1540 |
CYLD
BRSS CDMT CYLD1 CYLDI EAC MFT MFT1 SBS TEM USPL2 |
cylindromatosis (turban tumor syndrome) (EC:3.4.19.12) | Genistein results in increased expression of CYLD mRNA |
increases expression
|
mRNA |
18431742
|
| D019833 | 1540 |
CYLD
BRSS CDMT CYLD1 CYLDI EAC MFT MFT1 SBS TEM USPL2 |
cylindromatosis (turban tumor syndrome) (EC:3.4.19.12) | Genistein results in increased expression of CYLD protein |
increases expression
|
protein |
18431742
|
| D019833 | 1588 |
CYP19A1
ARO ARO1 CPV1 CYAR CYP19 CYPXIX P-450AROM |
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) | [Genistein co-treated with biochanin A co-treated with daidzein] results in decreased activity of CYP19A1 protein |
affects cotreatment
/ decreases activity |
protein |
16965912
|
| D019833 | 1588 |
CYP19A1
ARO ARO1 CPV1 CYAR CYP19 CYPXIX P-450AROM |
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) | [Genistein co-treated with biochanin A co-treated with daidzein] results in decreased expression of CYP19A1 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
16965912
|
| D019833 | 1588 |
CYP19A1
ARO ARO1 CPV1 CYAR CYP19 CYPXIX P-450AROM |
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) | Genistein inhibits the reaction [Fadrozole results in increased activity of CYP19A1 protein] |
decreases reaction
/ increases activity |
protein |
21854827
|
| D019833 | 1588 |
CYP19A1
ARO ARO1 CPV1 CYAR CYP19 CYPXIX P-450AROM |
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) | Genistein results in decreased activity of CYP19A1 protein |
decreases activity
|
protein |
15876411
16023337 16965912 |
| D019833 | 1588 |
CYP19A1
ARO ARO1 CPV1 CYAR CYP19 CYPXIX P-450AROM |
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) | Genistein results in decreased expression of CYP19A1 mRNA |
decreases expression
|
mRNA |
16965912
|
| D019833 | 1588 |
CYP19A1
ARO ARO1 CPV1 CYAR CYP19 CYPXIX P-450AROM |
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) | Genistein results in increased activity of CYP19A1 protein |
increases activity
|
protein |
15319488
|
| D019833 | 1588 |
CYP19A1
ARO ARO1 CPV1 CYAR CYP19 CYPXIX P-450AROM |
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) | Genistein results in increased expression of CYP19A1 mRNA |
increases expression
|
mRNA |
15319488
19549922 |
| D019833 | 1588 |
CYP19A1
ARO ARO1 CPV1 CYAR CYP19 CYPXIX P-450AROM |
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) | Genistein results in increased expression of CYP19A1 protein |
increases expression
|
protein |
21854827
|
| D019833 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | [Genistein co-treated with triclocarban] results in increased expression of CYP1A1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
23524099
|
| D019833 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | Genistein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
10696073
18451504 20057149 |
| D019833 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | Genistein results in decreased activity of CYP1A1 protein |
decreases activity
|
protein |
18497090
21053930 |
| D019833 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | Genistein results in decreased expression of CYP1A1 mRNA |
decreases expression
|
mRNA |
16474171
18451504 18497090 20884965 23019147 |
| D019833 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | Genistein results in increased activity of CYP1A1 protein |
increases activity
|
protein |
19766177
|
| D019833 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | Genistein results in increased expression of CYP1A1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 1544 |
CYP1A2
CP12 P3-450 P450(PA) |
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | CYP1A2 protein results in increased chemical synthesis of Genistein |
increases chemical synthesis
|
protein |
12814970
|
| D019833 | 1544 |
CYP1A2
CP12 P3-450 P450(PA) |
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | CYP1A2 protein results in increased metabolism of Genistein |
increases metabolic processing
|
protein |
12814970
|
| D019833 | 1544 |
CYP1A2
CP12 P3-450 P450(PA) |
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | Genistein results in decreased activity of CYP1A2 protein |
decreases activity
|
protein |
20806393
21053930 |
| D019833 | 1545 |
CYP1B1
CP1B CYPIB1 GLC3A P4501B1 |
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | CYP1B1 protein affects the chemical synthesis of Genistein |
affects chemical synthesis
|
protein |
15479032
|
| D019833 | 1545 |
CYP1B1
CP1B CYPIB1 GLC3A P4501B1 |
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | Genistein binds to and results in decreased activity of CYP1B1 protein |
affects binding
/ decreases activity |
protein |
21053930
|
| D019833 | 1545 |
CYP1B1
CP1B CYPIB1 GLC3A P4501B1 |
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | Genistein results in decreased activity of CYP1B1 protein |
decreases activity
|
protein |
15479032
|
| D019833 | 1545 |
CYP1B1
CP1B CYPIB1 GLC3A P4501B1 |
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | Genistein results in decreased expression of CYP1B1 mRNA |
decreases expression
|
mRNA |
15257099
16474171 |
| D019833 | 1545 |
CYP1B1
CP1B CYPIB1 GLC3A P4501B1 |
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | Genistein results in increased expression of CYP1B1 mRNA |
increases expression
|
mRNA |
16474171
23524099 |
| D019833 | 1545 |
CYP1B1
CP1B CYPIB1 GLC3A P4501B1 |
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | triclocarban promotes the reaction [Genistein results in increased expression of CYP1B1 mRNA] |
increases expression
/ increases reaction |
mRNA |
23524099
|
| D019833 | 1591 |
CYP24A1
CP24 CYP24 HCAI P450-CC24 |
cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) | Genistein inhibits the reaction [Calcitriol results in increased activity of CYP24A1 protein] |
decreases reaction
/ increases activity |
protein |
15955619
|
| D019833 | 1591 |
CYP24A1
CP24 CYP24 HCAI P450-CC24 |
cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) | Genistein inhibits the reaction [CYP24A1 protein results in increased degradation of Calcitriol] |
decreases reaction
/ increases degradation |
protein |
15955619
|
| D019833 | 1591 |
CYP24A1
CP24 CYP24 HCAI P450-CC24 |
cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) | Genistein promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] |
increases expression
/ increases reaction |
mRNA |
15955619
|
| D019833 | 1591 |
CYP24A1
CP24 CYP24 HCAI P450-CC24 |
cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) | Genistein results in decreased activity of CYP24A1 protein |
decreases activity
|
protein |
15955619
|
| D019833 | 1594 |
CYP27B1
CP2B CYP1 CYP1alpha CYP27B P450c1 PDDR VDD1 VDDR VDDRI VDR |
cytochrome P450, family 27, subfamily B, polypeptide 1 (EC:1.14.13.13) | Genistein affects the activity of CYP27B1 protein |
affects activity
|
protein |
17659868
|
| D019833 | 1594 |
CYP27B1
CP2B CYP1 CYP1alpha CYP27B P450c1 PDDR VDD1 VDDR VDDRI VDR |
cytochrome P450, family 27, subfamily B, polypeptide 1 (EC:1.14.13.13) | Genistein affects the expression of CYP27B1 mRNA |
affects expression
|
mRNA |
17659868
|
| D019833 | 1594 |
CYP27B1
CP2B CYP1 CYP1alpha CYP27B P450c1 PDDR VDD1 VDDR VDDRI VDR |
cytochrome P450, family 27, subfamily B, polypeptide 1 (EC:1.14.13.13) | Genistein results in increased activity of CYP27B1 protein |
increases activity
|
protein |
15795327
|
| D019833 | 1594 |
CYP27B1
CP2B CYP1 CYP1alpha CYP27B P450c1 PDDR VDD1 VDDR VDDRI VDR |
cytochrome P450, family 27, subfamily B, polypeptide 1 (EC:1.14.13.13) | Genistein results in increased expression of CYP27B1 mRNA |
increases expression
|
mRNA |
15795327
|
| D019833 | 1559 |
CYP2C9
CPC9 CYP2C CYP2C10 CYPIIC9 P450IIC9 |
cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) | Genistein inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] |
decreases reaction
/ increases hydroxylation |
protein |
21053930
|
| D019833 | 1576 |
CYP3A4
CP33 CP34 CYP3A CYP3A3 CYPIIIA3 CYPIIIA4 HLP NF-25 P450C3 P450PCN1 |
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) | Genistein inhibits the reaction [Calcitriol results in increased activity of CYP3A4 protein] |
decreases reaction
/ increases activity |
protein |
19766177
|
| D019833 | 1576 |
CYP3A4
CP33 CP34 CYP3A CYP3A3 CYPIIIA3 CYPIIIA4 HLP NF-25 P450C3 P450PCN1 |
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) | Genistein results in decreased activity of CYP3A4 protein |
decreases activity
|
protein |
21053930
|
| D019833 | 10858 |
CYP46A1
CP46 CYP46 |
cytochrome P450, family 46, subfamily A, polypeptide 1 (EC:1.14.13.98) | Genistein results in increased expression of CYP46A1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 1580 |
CYP4B1
CYPIVB1 P-450HP |
cytochrome P450, family 4, subfamily B, polypeptide 1 (EC:1.14.14.1) | Genistein results in decreased expression of CYP4B1 mRNA |
decreases expression
|
mRNA |
18444173
|
| D019833 | 8529 |
CYP4F2
CPF2 |
cytochrome P450, family 4, subfamily F, polypeptide 2 (EC:1.14.13.30) | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Genistein results in increased expression of CYP4F2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
21205922
|
| D019833 | 8529 |
CYP4F2
CPF2 |
cytochrome P450, family 4, subfamily F, polypeptide 2 (EC:1.14.13.30) | Genistein results in increased expression of CYP4F2 mRNA |
increases expression
|
mRNA |
21205922
|
| D019833 | 8529 |
CYP4F2
CPF2 |
cytochrome P450, family 4, subfamily F, polypeptide 2 (EC:1.14.13.30) | STO 609 inhibits the reaction [Genistein results in increased expression of CYP4F2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
21205922
|
| D019833 | 3491 |
CYR61
CCN1 GIG1 IGFBP10 |
cysteine-rich, angiogenic inducer, 61 | Genistein results in decreased expression of CYR61 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 9267 |
CYTH1
B2-1 CYTOHESIN-1 D17S811E PSCD1 SEC7 |
cytohesin 1 | Genistein results in decreased expression of CYTH1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 9265 |
CYTH3
ARNO3 GRP1 PSCD3 |
cytohesin 3 | Genistein results in decreased expression of CYTH3 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 1603 |
DAD1
OST2 |
defender against cell death 1 (EC:2.4.99.18) | Genistein results in increased expression of DAD1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 55861 |
DBNDD2
C20orf35 CK1BP HSMNP1 |
dysbindin (dystrobrevin binding protein 1) domain containing 2 | Genistein results in decreased expression of DBNDD2 mRNA |
decreases expression
|
mRNA |
18847459
|
| D019833 | 1638 |
DCT
TRP-2 TYRP2 |
dopachrome tautomerase (EC:5.3.3.12) | Genistein results in decreased expression of DCT mRNA |
decreases expression
|
mRNA |
16705744
18444173 |
| D019833 | 51181 |
DCXR
DCR HCR2 HCRII KIDCR P34H SDR20C1 XR |
dicarbonyl/L-xylulose reductase (EC:1.1.1.10) | Genistein results in increased expression of DCXR mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 1644 |
DDC
AADC |
dopa decarboxylase (aromatic L-amino acid decarboxylase) (EC:4.1.1.28) | Genistein results in increased expression of DDC mRNA |
increases expression
|
mRNA |
15378649
|
| D019833 | 1649 |
DDIT3
CEBPZ CHOP CHOP-10 CHOP10 GADD153 |
DNA-damage-inducible transcript 3 | Genistein results in decreased expression of DDIT3 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 1649 |
DDIT3
CEBPZ CHOP CHOP-10 CHOP10 GADD153 |
DNA-damage-inducible transcript 3 | Genistein results in increased expression of DDIT3 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 65992 |
DDRGK1
C20orf116 UFBP1 dJ1187M17.3 |
DDRGK domain containing 1 | ESR2 promotes the reaction [Genistein results in decreased expression of DDRGK1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 65992 |
DDRGK1
C20orf116 UFBP1 dJ1187M17.3 |
DDRGK domain containing 1 | Genistein results in decreased expression of DDRGK1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 123099 |
DEGS2
C14orf66 DES2 FADS8 |
delta(4)-desaturase, sphingolipid 2 | Genistein results in increased expression of DEGS2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 55789 |
DEPDC1B
BRCC3 XTP1 |
DEP domain containing 1B | Genistein results in increased expression of DEPDC1B mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 420357 | Genistein results in increased expression of DEPDC6 mRNA |
increases expression
|
mRNA |
23019147
|
||
| D019833 | 1677 |
DFFB
CAD CPAN DFF-40 DFF2 DFF40 |
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | Genistein results in increased expression of DFFB mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 84649 |
DGAT2
ARAT GS1999FULL |
diacylglycerol O-acyltransferase 2 (EC:2.3.1.20 2.3.1.76) | Genistein results in increased expression of DGAT2 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 8526 |
DGKE
DAGK5 DAGK6 DGK NPHS7 |
diacylglycerol kinase, epsilon 64kDa (EC:2.7.1.107) | Genistein results in increased expression of DGKE mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 1718 |
DHCR24
DCE Nbla03646 SELADIN1 seladin-1 |
24-dehydrocholesterol reductase (EC:1.3.1.72) | Genistein results in decreased expression of DHCR24 mRNA |
decreases expression
|
mRNA |
15378649
|
| D019833 | 200895 |
DHFRL1
DHFRP4 |
dihydrofolate reductase-like 1 (EC:1.5.1.3) | Genistein results in increased expression of DHFRL1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 308585 | Genistein results in decreased expression of DHRS10 mRNA |
decreases expression
|
mRNA |
19371625
|
||
| D019833 | 10202 |
DHRS2
HEP27 SDR25C1 |
dehydrogenase/reductase (SDR family) member 2 | Genistein results in increased expression of DHRS2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 9249 |
DHRS3
DD83.1 RDH17 Rsdr1 SDR1 SDR16C1 retSDR1 |
dehydrogenase/reductase (SDR family) member 3 (EC:1.1.1.300) | Genistein results in increased expression of DHRS3 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 22943 |
DKK1
DKK-1 SK |
dickkopf WNT signaling pathway inhibitor 1 | Genistein results in decreased expression of DKK1 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 9231 |
DLG5
LP-DLG P-DLG5 PDLG |
discs, large homolog 5 (Drosophila) | Genistein results in increased expression of DLG5 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 9787 |
DLGAP5
DLG7 HURP |
discs, large (Drosophila) homolog-associated protein 5 | Genistein affects the expression of DLGAP5 mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 1756 |
DMD
BMD CMD3B DXS142 DXS164 DXS206 DXS230 DXS239 DXS268 DXS269 DXS270 DXS272 |
dystrophin | ESR2 promotes the reaction [Genistein results in decreased expression of DMD protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 1756 |
DMD
BMD CMD3B DXS142 DXS164 DXS206 DXS230 DXS239 DXS268 DXS269 DXS270 DXS272 |
dystrophin | Genistein results in decreased expression of DMD protein |
decreases expression
|
protein |
20884965
|
| D019833 | 4189 |
DNAJB9
ERdj4 MDG-1 MDG1 MST049 MSTP049 |
DnaJ (Hsp40) homolog, subfamily B, member 9 | Genistein results in increased expression of DNAJB9 mRNA |
increases expression
|
mRNA |
15378649
|
| D019833 | 55192 |
DNAJC17
|
DnaJ (Hsp40) homolog, subfamily C, member 17 | Genistein results in decreased expression of DNAJC17 mRNA |
decreases expression
|
mRNA |
18847459
|
| D019833 | 134218 |
DNAJC21
DNAJA5 GS3 JJJ1 |
DnaJ (Hsp40) homolog, subfamily C, member 21 | Genistein results in increased expression of DNAJC21 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 1786 |
DNMT1
ADCADN AIM CXXC9 DNMT HSN1E MCMT |
DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) | Genistein results in decreased expression of DNMT1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 1786 |
DNMT1
ADCADN AIM CXXC9 DNMT HSN1E MCMT |
DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) | Genistein results in decreased expression of DNMT1 protein |
decreases expression
|
protein |
19221000
|
| D019833 | 1789 |
DNMT3B
ICF ICF1 M.HsaIIIB |
DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37) | Genistein results in decreased expression of DNMT3B protein |
decreases expression
|
protein |
19221000
|
| D019833 | 23549 |
DNPEP
ASPEP DAP |
aspartyl aminopeptidase (EC:3.4.11.21) | ESR2 promotes the reaction [Genistein results in decreased expression of DNPEP protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 23549 |
DNPEP
ASPEP DAP |
aspartyl aminopeptidase (EC:3.4.11.21) | Genistein results in decreased expression of DNPEP protein |
decreases expression
|
protein |
20884965
|
| D019833 | 1795 |
DOCK3
MOCA PBP |
dedicator of cytokinesis 3 | [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of DOCK3 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
16963248
|
| D019833 | 83475 |
DOHH
HLRC1 hDOHH |
deoxyhypusine hydroxylase/monooxygenase (EC:1.14.99.29) | Genistein results in increased expression of DOHH mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 55715 |
DOK4
|
docking protein 4 | Genistein results in increased expression of DOK4 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 285489 |
DOK7
C4orf25 CMS1B |
docking protein 7 | Genistein results in increased expression of DOK7 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 1819 |
DRG2
|
developmentally regulated GTP binding protein 2 | Genistein results in decreased expression of DRG2 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 1819 |
DRG2
|
developmentally regulated GTP binding protein 2 | Genistein results in increased expression of DRG2 mRNA |
increases expression
|
mRNA |
16705744
|
| D019833 | 1830 |
DSG3
CDHF6 PVA |
desmoglein 3 | Genistein results in decreased expression of DSG3 mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 51514 |
DTL
CDT2 DCAF2 L2DTL RAMP |
denticleless E3 ubiquitin protein ligase homolog (Drosophila) | Genistein results in increased expression of DTL mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 23220 |
DTX4
RNF155 |
deltex homolog 4 (Drosophila) | Genistein results in increased expression of DTX4 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 1841 |
DTYMK
CDC8 PP3731 TMPK TYMK |
deoxythymidylate kinase (thymidylate kinase) (EC:2.7.4.9) | Genistein results in increased expression of DTYMK mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 1843 |
DUSP1
CL100 HVH1 MKP-1 MKP1 PTPN10 |
dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) | Genistein results in decreased expression of DUSP1 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 1843 |
DUSP1
CL100 HVH1 MKP-1 MKP1 PTPN10 |
dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) | Genistein results in increased expression of DUSP1 mRNA |
increases expression
|
mRNA |
16705744
|
| D019833 | 1844 |
DUSP2
PAC-1 PAC1 |
dual specificity phosphatase 2 (EC:3.1.3.16 3.1.3.48) | Genistein results in increased expression of DUSP2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 1846 |
DUSP4
HVH2 MKP-2 MKP2 TYP |
dual specificity phosphatase 4 (EC:3.1.3.16 3.1.3.48) | Genistein results in decreased expression of DUSP4 mRNA |
decreases expression
|
mRNA |
16865672
|
| D019833 | 1847 |
DUSP5
DUSP HVH3 |
dual specificity phosphatase 5 (EC:3.1.3.16 3.1.3.48) | Genistein results in decreased expression of DUSP5 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 1848 |
DUSP6
HH19 MKP3 PYST1 |
dual specificity phosphatase 6 (EC:3.1.3.16 3.1.3.48) | Genistein results in increased expression of DUSP6 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 1855 |
DVL1
DVL DVL1L1 DVL1P1 |
dishevelled segment polarity protein 1 | Genistein results in increased expression of DVL1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 1870 |
E2F2
E2F-2 |
E2F transcription factor 2 | Genistein results in decreased expression of E2F2 mRNA |
decreases expression
|
mRNA |
18847459
|
| D019833 | 9166 |
EBAG9
EB9 PDAF |
estrogen receptor binding site associated, antigen, 9 | Genistein results in increased expression of EBAG9 mRNA |
increases expression
|
mRNA |
17266178
|
| D019833 | 10682 |
EBP
CDPX2 CHO2 CPX CPXD |
emopamil binding protein (sterol isomerase) (EC:5.3.3.5) | Genistein results in increased expression of EBP mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 1889 |
ECE1
ECE |
endothelin converting enzyme 1 (EC:3.4.24.71) | Genistein results in decreased expression of ECE1 mRNA |
decreases expression
|
mRNA |
16399490
|
| D019833 | 1891 |
ECH1
HPXEL |
enoyl CoA hydratase 1, peroxisomal | Genistein results in decreased expression of ECH1 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 1894 |
ECT2
ARHGEF31 |
epithelial cell transforming sequence 2 oncogene | Genistein results in increased expression of ECT2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 23644 |
EDC4
GE1 Ge-1 HEDL5 HEDLS RCD-8 RCD8 |
enhancer of mRNA decapping 4 | Genistein results in decreased expression of EDC4 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 1906 |
EDN1
ET1 HDLCQ7 PPET1 |
endothelin 1 | Genistein affects the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]] |
affects binding
/ affects reaction / increases reaction |
promoter |
10939628
|
| D019833 | 1906 |
EDN1
ET1 HDLCQ7 PPET1 |
endothelin 1 | Genistein affects the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]] |
affects binding
/ affects reaction / increases reaction |
promoter |
10939628
|
| D019833 | 1906 |
EDN1
ET1 HDLCQ7 PPET1 |
endothelin 1 | Genistein inhibits the reaction [cobaltous chloride results in increased expression of EDN1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
10939628
|
| D019833 | 1906 |
EDN1
ET1 HDLCQ7 PPET1 |
endothelin 1 | Genistein inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
10939628
|
| D019833 | 1907 |
EDN2
ET2 PPET2 |
endothelin 2 | Genistein results in decreased expression of EDN2 mRNA |
decreases expression
|
mRNA |
16399490
|
| D019833 | 1938 |
EEF2
EEF-2 EF-2 EF2 SCA26 |
eukaryotic translation elongation factor 2 | Genistein results in decreased expression of EEF2 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 80303 |
EFHD1
MST133 MSTP133 SWS2 |
EF-hand domain family, member D1 | ESR2 promotes the reaction [Genistein results in increased expression of EFHD1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 80303 |
EFHD1
MST133 MSTP133 SWS2 |
EF-hand domain family, member D1 | Genistein results in increased expression of EFHD1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 1948 |
EFNB2
EPLG5 HTKL Htk-L LERK5 |
ephrin-B2 | Genistein results in decreased expression of EFNB2 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 1950 |
EGF
HOMG4 URG |
epidermal growth factor | Genistein inhibits the reaction [EGF protein results in increased activity of AKT1 protein] |
decreases reaction
/ increases activity |
protein |
18431742
|
| D019833 | 1950 |
EGF
HOMG4 URG |
epidermal growth factor | Genistein results in decreased expression of EGF mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 1956 |
EGFR
ERBB ERBB1 HER1 PIG61 mENA |
epidermal growth factor receptor (EC:2.7.10.1) | [Genistein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA |
affects cotreatment
/ decreases expression |
mRNA |
19347870
|
| D019833 | 1956 |
EGFR
ERBB ERBB1 HER1 PIG61 mENA |
epidermal growth factor receptor (EC:2.7.10.1) | [Genistein co-treated with ESR1 protein] results in decreased expression of EGFR protein |
affects cotreatment
/ decreases expression |
protein |
19347870
|
| D019833 | 1956 |
EGFR
ERBB ERBB1 HER1 PIG61 mENA |
epidermal growth factor receptor (EC:2.7.10.1) | [Genistein co-treated with ESR2 protein] results in decreased expression of EGFR mRNA |
affects cotreatment
/ decreases expression |
mRNA |
19347870
|
| D019833 | 1956 |
EGFR
ERBB ERBB1 HER1 PIG61 mENA |
epidermal growth factor receptor (EC:2.7.10.1) | [Genistein co-treated with ESR2 protein] results in decreased expression of EGFR protein |
affects cotreatment
/ decreases expression |
protein |
19347870
|
| D019833 | 1956 |
EGFR
ERBB ERBB1 HER1 PIG61 mENA |
epidermal growth factor receptor (EC:2.7.10.1) | Genistein results in decreased expression of EGFR mRNA |
decreases expression
|
mRNA |
15257099
|
| D019833 | 1958 |
EGR1
AT225 G0S30 KROX-24 NGFI-A TIS8 ZIF-268 ZNF225 |
early growth response 1 | Genistein results in increased expression of EGR1 mRNA |
increases expression
|
mRNA |
15257099
23019147 |
| D019833 | 1960 |
EGR3
EGR-3 PILOT |
early growth response 3 | Genistein results in increased expression of EGR3 mRNA |
increases expression
|
mRNA |
15159206
|
| D019833 | 1981 |
EIF4G1
EIF-4G1 EIF4F EIF4G EIF4GI P220 PARK18 |
eukaryotic translation initiation factor 4 gamma, 1 | ESR2 promotes the reaction [Genistein results in decreased expression of EIF4G1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 1981 |
EIF4G1
EIF-4G1 EIF4F EIF4G EIF4GI P220 PARK18 |
eukaryotic translation initiation factor 4 gamma, 1 | Genistein results in decreased expression of EIF4G1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 1984 |
EIF5A
EIF-5A EIF5A1 eIF5AI |
eukaryotic translation initiation factor 5A | Genistein results in decreased expression of EIF5A mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 64834 |
ELOVL1
Ssc1 |
ELOVL fatty acid elongase 1 (EC:2.3.1.199) | ESR2 promotes the reaction [Genistein results in increased expression of ELOVL1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 64834 |
ELOVL1
Ssc1 |
ELOVL fatty acid elongase 1 (EC:2.3.1.199) | Genistein results in increased expression of ELOVL1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 83401 |
ELOVL3
CIG-30 CIG30 |
ELOVL fatty acid elongase 3 (EC:2.3.1.199) | Genistein results in increased expression of ELOVL3 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 60481 |
ELOVL5
HELO1 dJ483K16.1 |
ELOVL fatty acid elongase 5 (EC:2.3.1.199) | Genistein results in decreased expression of ELOVL5 mRNA |
decreases expression
|
mRNA |
15378649
|
| D019833 | 2013 |
EMP2
XMP |
epithelial membrane protein 2 | Genistein results in increased expression of EMP2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 2026 |
ENO2
NSE |
enolase 2 (gamma, neuronal) (EC:4.2.1.11) | Genistein results in decreased expression of ENO2 mRNA |
decreases expression
|
mRNA |
15159206
|
| D019833 | 2027 |
ENO3
GSD13 MSE |
enolase 3 (beta, muscle) (EC:4.2.1.11) | Genistein results in decreased expression of ENO3 mRNA |
decreases expression
|
mRNA |
15757668
|
| D019833 | 5168 |
ENPP2
ATX ATX-X AUTOTAXIN LysoPLD NPP2 PD-IALPHA PDNP2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 (EC:3.1.4.39) | Genistein results in decreased expression of ENPP2 mRNA |
decreases expression
|
mRNA |
15256057
|
| D019833 | 2036 |
EPB41L1
4.1N MRD11 |
erythrocyte membrane protein band 4.1-like 1 | Genistein results in increased expression of EPB41L1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 2037 |
EPB41L2
4.1-G 4.1G |
erythrocyte membrane protein band 4.1-like 2 | Genistein results in increased expression of EPB41L2 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 2041 |
EPHA1
EPH EPHT EPHT1 |
EPH receptor A1 (EC:2.7.10.1) | [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of EPHA1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
16963248
|
| D019833 | 2050 |
EPHB4
HTK MYK1 TYRO11 |
EPH receptor B4 (EC:2.7.10.1) | Genistein results in decreased expression of EPHB4 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 2052 |
EPHX1
EPHX EPOX HYL1 MEH |
epoxide hydrolase 1, microsomal (xenobiotic) (EC:3.3.2.9) | Genistein results in increased expression of EPHX1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 2053 |
EPHX2
CEH SEH |
epoxide hydrolase 2, cytoplasmic (EC:3.3.2.10 3.1.3.76) | ESR2 promotes the reaction [Genistein results in increased expression of EPHX2 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 2053 |
EPHX2
CEH SEH |
epoxide hydrolase 2, cytoplasmic (EC:3.3.2.10 3.1.3.76) | Genistein results in increased expression of EPHX2 protein |
increases expression
|
protein |
20884965
|
| D019833 | 2057 |
EPOR
EPO-R |
erythropoietin receptor | Genistein results in increased expression of EPOR mRNA |
increases expression
|
mRNA |
16705744
|
| D019833 | 2068 |
ERCC2
COFS2 EM9 TTD XPD |
excision repair cross-complementing rodent repair deficiency, complementation group 2 (EC:3.6.4.12) | Genistein results in decreased expression of ERCC2 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 2071 |
ERCC3
BTF2 GTF2H RAD25 TFIIH XPB |
excision repair cross-complementing rodent repair deficiency, complementation group 3 (EC:3.6.4.12) | Genistein results in increased expression of ERCC3 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 1161 |
ERCC8
CKN1 CSA UVSS2 |
excision repair cross-complementing rodent repair deficiency, complementation group 8 | Genistein results in increased expression of ERCC8 mRNA |
increases expression
|
mRNA |
16705744
|
| D019833 | 11160 |
ERLIN2
C8orf2 Erlin-2 NET32 SPFH2 SPG18 |
ER lipid raft associated 2 | Genistein results in decreased expression of ERLIN2 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 83715 |
ESPN
DFNB36 |
espin | [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ESPN mRNA |
affects cotreatment
/ decreases expression |
mRNA |
16963248
|
| D019833 | 83715 |
ESPN
DFNB36 |
espin | Genistein results in increased expression of ESPN mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 284729 |
ESPNP
RP1-163M9.1 dJ1182A14.1 |
espin pseudogene | Genistein results in increased expression of ESPNP mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [Genistein binds to and results in increased activity of ESR1 protein] |
affects binding
/ decreases reaction / increases activity |
protein |
11861976
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane promotes the reaction [Genistein binds to and results in increased activity of ESR1 protein] |
affects binding
/ increases activity / increases reaction |
protein |
11861976
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | [afimoxifene binds to and results in decreased activity of ESR1 protein] which results in decreased susceptibility to Genistein |
affects binding
/ decreases activity / decreases response to substance |
protein |
19427779
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | beta Carotene inhibits the reaction [Genistein results in increased activity of ESR1 protein] |
decreases reaction
/ increases activity |
protein |
17051425
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of ACTBL2 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of APLP2 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of BCKDHA protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of CHCHD1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of CHMP2B protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of HMGN1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of HNRNPC protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of KPRP protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of LGALS7 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of LMNA protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of LMNB1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of LPP protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of MAP4 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of MOGS protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of MYO15A protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of NASP protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of NFS1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of NLN protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of NPC2 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of PIP protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of PNKD protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of POFUT1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of RPS16 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of RPS18 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of RPS25 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of RPS29 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of S100A8 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of S100A9 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of SEPHS1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of SYAP1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of THOC2 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of TIMM10B protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of TOMM40 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of TPR protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in decreased expression of VAT1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of ASNS protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of CCDC25 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of FAM129A protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of KRT18 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of KRT19 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of KRT8 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of MGP protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of MRPL20 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of MYH10 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of MYH14 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of MYH9 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of MYL12B protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of MYL6 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of NBN protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of NFAT5 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of NPM1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of RCN1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of RPL23AP37 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of SLC3A2 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of SLC7A5 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of TMEM120A protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 promotes the reaction [Genistein results in increased expression of TTBK2 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 protein affects the susceptibility to Genistein |
affects response to substance
|
protein |
17275032
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 protein inhibits the reaction [Genistein results in increased expression of PGR mRNA] |
decreases reaction
/ increases expression |
protein |
23384675
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 protein inhibits the reaction [Genistein results in increased expression of PRSS23 mRNA] |
decreases reaction
/ increases expression |
protein |
23384675
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 protein inhibits the reaction [Genistein results in increased expression of TFF1 mRNA] |
decreases reaction
/ increases expression |
protein |
23384675
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | ESR1 protein inhibits the reaction [Genistein results in increased expression of WISP2 mRNA] |
decreases reaction
/ increases expression |
protein |
23384675
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | [Estradiol co-treated with Genistein co-treated with o,p'-DDT] affects the expression of ESR1 mRNA |
affects cotreatment
/ affects expression |
mRNA |
11922773
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | [fulvestrant binds to and results in decreased activity of ESR1 protein] which results in decreased susceptibility to Genistein |
affects binding
/ decreases activity / decreases response to substance |
protein |
19427779
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | fulvestrant inhibits the reaction [[Genistein binds to ESR1 protein] which results in increased activity of ALPL protein] |
affects binding
/ decreases reaction / increases activity |
protein |
12650720
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | fulvestrant inhibits the reaction [Genistein results in increased activity of ESR1 protein] |
decreases reaction
/ increases activity |
protein |
20599613
22562034 |
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein binds to and results in increased activity of ESR1 protein |
affects binding
/ increases activity |
protein |
9751507
10397250 11502892 11861976 12765243 15026083 15876408 15937998 16076101 16541309 20362049 20435135 |
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein binds to ESR1 protein |
affects binding
|
protein |
11162928
11368622 11518614 11999068 12598185 14579009 15521089 16506809 16566672 17400923 18692112 19913605 20074635 |
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | [Genistein binds to ESR1 protein] which binds to NCOA2 protein |
affects binding
|
protein |
15123288
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | [Genistein binds to ESR1 protein] which results in increased activity of ALPL protein |
affects binding
/ increases activity |
protein |
12650720
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | [Genistein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA |
affects cotreatment
/ decreases expression |
protein |
19347870
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | [Genistein co-treated with ESR1 protein] results in decreased expression of EGFR protein |
affects cotreatment
/ decreases expression |
protein |
19347870
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | [Genistein co-treated with ESR1 protein] results in increased expression of BGLAP mRNA |
affects cotreatment
/ increases expression |
protein |
19347870
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | [Genistein co-treated with ESR1 protein] results in increased expression of LTF mRNA |
affects cotreatment
/ increases expression |
protein |
21783566
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | [Genistein co-treated with ESR1] results in increased expression of BSP mRNA |
affects cotreatment
/ increases expression |
19347870
|
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein inhibits the reaction [16 alpha-iodoestradiol binds to ESR1 protein] |
affects binding
/ decreases reaction |
protein |
9048584
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein inhibits the reaction [Estradiol binds to ESR1 protein] |
affects binding
/ decreases reaction |
protein |
10964929
11368622 14579009 16566672 |
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein inhibits the reaction [Estradiol results in increased activity of ESR1 protein] |
decreases reaction
/ increases activity |
protein |
16434996
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein promotes the reaction [ESR1 protein binds to ESR1 protein] |
affects binding
/ increases reaction |
protein |
15713566
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein promotes the reaction [ESR1 protein binds to GREB1 promoter] |
affects binding
/ increases reaction |
protein |
23019147
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein promotes the reaction [ESR1 protein binds to JUND promoter] |
affects binding
/ increases reaction |
protein |
23019147
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein promotes the reaction [ESR1 protein binds to NCOA1 protein] |
affects binding
/ increases reaction |
protein |
10964929
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein promotes the reaction [ESR1 protein binds to NCOA2 protein] |
affects binding
/ increases reaction |
protein |
10964929
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein promotes the reaction [Estradiol results in increased activity of ESR1 protein] |
increases activity
/ increases reaction |
protein |
16118406
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein promotes the reaction [NCOA2 protein binds to ESR1 protein] |
affects binding
/ increases reaction |
protein |
15084758
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein results in decreased expression of ESR1 mRNA |
decreases expression
|
mRNA |
11502892
15968319 16033089 23524099 |
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein results in decreased expression of ESR1 protein |
decreases expression
|
protein |
11502892
16033089 16541309 |
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein results in increased activity of ESR1 protein |
increases activity
|
protein |
11485867
14975756 16118406 17132221 19161236 20599613 22562034 23019147 |
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Genistein results in increased expression of ESR1 mRNA |
increases expression
|
mRNA |
11922773
15968319 |
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Methoxychlor metabolite inhibits the reaction [Genistein binds to and results in increased activity of ESR1 protein] |
affects binding
/ decreases reaction / increases activity |
protein |
11861976
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | Methoxychlor metabolite promotes the reaction [Genistein binds to and results in increased activity of ESR1 protein] |
affects binding
/ increases activity / increases reaction |
protein |
11861976
|
| D019833 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | RU 58668 promotes the reaction [fulvestrant inhibits the reaction [Genistein results in increased activity of ESR1 protein]] |
decreases reaction
/ increases activity / increases reaction |
protein |
20599613
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [Genistein binds to and results in increased activity of ESR2 protein] |
affects binding
/ decreases reaction / increases activity |
protein |
11861976
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | beta Carotene inhibits the reaction [Genistein results in increased activity of ESR2 protein] |
decreases reaction
/ increases activity |
protein |
17051425
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 affects the reaction [Genistein results in increased expression of CDKN1A] |
affects reaction
/ increases expression |
21161820
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 affects the susceptibility to Genistein |
affects response to substance
|
21161820
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 gene polymorphism affects the reaction [[Genistein co-treated with daidzein] affects the expression of VCAM1 protein] |
affects cotreatment
/ affects expression / affects reaction |
gene |
16332659
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 gene polymorphism affects the susceptibility to [Genistein co-treated with daidzein] |
affects cotreatment
/ affects response to substance |
gene |
16332659
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of ABAT protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of ACLY protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of ACOX1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of ADSL protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of ANXA1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of ANXA3 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of ARMCX3 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of BAG5 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of CNN2 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of COTL1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of COX7A2L protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of CSRP1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of CYB5A protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of DDRGK1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of DMD protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of DNPEP protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of EIF4G1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of ESR2 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of FHL2 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of FLNA protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of GPS1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of H2AFZ protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of HIST1H2AG protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of HIST1H4A protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of HNRNPC protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of ISG15 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of ISYNA1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of ITGAV protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of LDHB protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of LMNA protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of LMNB2 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of MAP4 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of MATR3 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of MX1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of NFKB2 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of PPL protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of PRAF2 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of PREX1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of PRSS8 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of REEP5 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of RPL38 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of S100A16 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of S100A8 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of SDHB protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of SLK protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of SRPR protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of STAT1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of TNKS1BP1 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of TOP2B protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of TTC9C protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of UBE2L6 protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of UBTF protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of UGDH protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in decreased expression of VCL protein] |
decreases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of ACY1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of ANKRD36B protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of APRT protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of ARMC10 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of CANX protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of CBX5 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of CD9 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of CLDN1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of CNPY2 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of COMTD1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of CRIP1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of EFHD1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of ELOVL1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of EPHX2 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of ESR2 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of FGFR2 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of GIPC1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of GOT2 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of H1F0 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1B protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1C protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1E protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2AB protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2AG protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2BN protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of HIST1H4A protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of HNRNPA2B1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of HNRNPC protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of HNRNPUL2 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of HSD17B8 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of HSPA9 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of ISYNA1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of KIAA0753 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of KIAA1107 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of KRT18 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of KRT19 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of KRT8 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of LAMP2 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of LMNA protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of LYRM7 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of MATR3 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of METTL7A protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of MGP protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of MUC1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of NPM1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of NUMA1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of PIP protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of PRMT1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of PTGR2 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of PYGB protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of RAB18 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of REEP5 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of RNMTL1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of RNPEP protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of S100A9 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of SEPHS1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of SLC9A3R1 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of TFRC protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of TP53I3 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of TRMT112 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 promotes the reaction [Genistein results in increased expression of VPS24 protein] |
increases expression
/ increases reaction |
20884965
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | ESR2 protein affects the susceptibility to Genistein |
affects response to substance
|
protein |
17275032
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Genistein binds to and results in increased activity of ESR2 protein |
affects binding
/ increases activity |
protein |
9751507
11502892 11861976 12547825 12765243 15084758 15937998 16076101 |
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Genistein binds to ESR2 protein |
affects binding
|
protein |
10964929
11368622 11518614 12224631 15887952 16506809 16566672 19913605 20160136 |
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | [Genistein binds to ESR2 protein] which binds to NCOA2 protein |
affects binding
|
protein |
15123288
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | [Genistein co-treated with ESR2 protein] results in decreased expression of EGFR mRNA |
affects cotreatment
/ decreases expression |
protein |
19347870
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | [Genistein co-treated with ESR2 protein] results in decreased expression of EGFR protein |
affects cotreatment
/ decreases expression |
protein |
19347870
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | [Genistein co-treated with ESR2 protein] results in increased expression of BGLAP mRNA |
affects cotreatment
/ increases expression |
protein |
19347870
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | [Genistein co-treated with ESR2 protein] results in increased expression of LTF mRNA |
affects cotreatment
/ increases expression |
protein |
21783566
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | [Genistein co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA |
affects cotreatment
/ increases expression |
protein |
19347870
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | [Genistein co-treated with ESR2] results in increased expression of BSP mRNA |
affects cotreatment
/ increases expression |
19347870
|
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Genistein inhibits the reaction [Estradiol binds to ESR2 protein] |
affects binding
/ decreases reaction |
protein |
9751507
10964929 11368622 16566672 |
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Genistein promotes the reaction [ESR2 protein binds to NCOA1 protein] |
affects binding
/ increases reaction |
protein |
10964929
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Genistein promotes the reaction [ESR2 protein binds to NCOA2 protein] |
affects binding
/ increases reaction |
protein |
10964929
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Genistein promotes the reaction [Estradiol results in increased activity of ESR2 protein] |
increases activity
/ increases reaction |
protein |
16118406
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Genistein results in decreased expression of ESR2 mRNA |
decreases expression
|
mRNA |
15968319
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Genistein results in decreased expression of ESR2 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Genistein results in increased activity of ESR2 protein |
increases activity
|
protein |
16118406
17132221 18937077 18955141 19161236 |
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Genistein results in increased activity of ESR2 protein alternative form |
increases activity
|
protein |
17266178
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Genistein results in increased expression of ESR2 mRNA |
increases expression
|
mRNA |
16033089
16596234 20884965 |
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Genistein results in increased expression of ESR2 mRNA alternative form |
increases expression
|
mRNA |
16596234
|
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Genistein results in increased expression of ESR2 protein |
increases expression
|
protein |
16033089
20884965 |
| D019833 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Methoxychlor metabolite inhibits the reaction [Genistein binds to and results in increased activity of ESR2 protein] |
affects binding
/ decreases reaction / increases activity |
protein |
11861976
|
| D019833 | 2101 |
ESRRA
ERR1 ERRa ERRalpha ESRL1 NR3B1 |
estrogen-related receptor alpha | Genistein binds to and results in increased activity of ESRRA protein |
affects binding
/ increases activity |
protein |
14638870
15955695 |
| D019833 | 2101 |
ESRRA
ERR1 ERRa ERRalpha ESRL1 NR3B1 |
estrogen-related receptor alpha | Genistein binds to and results in increased activity of ESRRA protein mutant form |
affects binding
/ increases activity |
protein |
14638870
|
| D019833 | 2101 |
ESRRA
ERR1 ERRa ERRalpha ESRL1 NR3B1 |
estrogen-related receptor alpha | Genistein results in increased expression of ESRRA mRNA |
increases expression
|
mRNA |
16399490
23019147 |
| D019833 | 2103 |
ESRRB
DFNB35 ERR2 ERRb ESRL2 NR3B2 |
estrogen-related receptor beta | Genistein binds to and results in increased activity of ESRRB protein |
affects binding
/ increases activity |
protein |
14638870
|
| D019833 | 2103 |
ESRRB
DFNB35 ERR2 ERRb ESRL2 NR3B2 |
estrogen-related receptor beta | Genistein promotes the reaction [ESRRB protein binds to PNRC1 protein] |
affects binding
/ increases reaction |
protein |
14638870
|
| D019833 | 2104 |
ESRRG
ERR3 ERRgamma NR3B3 |
estrogen-related receptor gamma | Genistein promotes the reaction [ESRRG protein binds to PNRC1 protein] |
affects binding
/ increases reaction |
protein |
14638870
|
| D019833 | 55224 |
ETNK2
EKI2 HMFT1716 |
ethanolamine kinase 2 (EC:2.7.1.82) | Genistein results in increased expression of ETNK2 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 2114 |
ETS2
ETS2IT1 |
v-ets avian erythroblastosis virus E26 oncogene homolog 2 | Genistein results in decreased expression of ETS2 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 2137 |
EXTL3
BOTV EXTL1L EXTR1 REGR RPR |
exostosin-like glycosyltransferase 3 (EC:2.4.1.223) | Genistein results in decreased expression of EXTL3 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 9415 |
FADS2
D6D DES6 FADSD6 LLCDL2 SLL0262 TU13 |
fatty acid desaturase 2 (EC:1.14.19.-) | Genistein results in decreased expression of FADS2 mRNA |
decreases expression
|
mRNA |
20816778
|
| D019833 | 399665 |
FAM102A
C9orf132 EEIG1 SYM-3A bA203J24.7 |
family with sequence similarity 102, member A | Genistein results in increased expression of FAM102A mRNA |
increases expression
|
mRNA |
14605097
|
| D019833 | 11170 |
FAM107A
DRR1 TU3A |
family with sequence similarity 107, member A | Genistein results in decreased expression of FAM107A mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 116224 |
FAM122A
C9orf42 |
family with sequence similarity 122A | Genistein results in increased expression of FAM122A mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 116496 |
FAM129A
C1orf24 NIBAN |
family with sequence similarity 129, member A | ESR1 promotes the reaction [Genistein results in increased expression of FAM129A protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 116496 |
FAM129A
C1orf24 NIBAN |
family with sequence similarity 129, member A | Genistein results in increased expression of FAM129A protein |
increases expression
|
protein |
20884965
|
| D019833 | 23201 |
FAM168A
KIAA0280 TCRP1 |
family with sequence similarity 168, member A | Genistein results in decreased expression of FAM168A mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 84331 |
FAM195A
C16orf14 c349E10.1 |
family with sequence similarity 195, member A | Genistein results in increased expression of FAM195A mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 131583 |
FAM43A
|
family with sequence similarity 43, member A | Genistein results in increased expression of FAM43A mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 81610 |
FAM83D
C20orf129 CHICA dJ616B8.3 |
family with sequence similarity 83, member D | Genistein results in increased expression of FAM83D mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 157638 |
FAM84B
BCMP101 NSE2 |
family with sequence similarity 84, member B | Genistein results in decreased expression of FAM84B mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 2176 |
FANCC
FA3 FAC FACC |
Fanconi anemia, complementation group C | Genistein results in decreased expression of FANCC mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 55215 |
FANCI
KIAA1794 |
Fanconi anemia, complementation group I | Genistein results in increased expression of FANCI mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 10160 |
FARP1
CDEP PLEKHC2 PPP1R75 |
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | Genistein results in increased expression of FARP1 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 2192 |
FBLN1
FBLN FIBL1 |
fibulin 1 | Genistein results in increased expression of FBLN1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 2200 |
FBN1
ACMICD ECTOL1 FBN GPHYSD2 MASS MFS1 OCTD SGS SSKS WMS WMS2 |
fibrillin 1 | Genistein results in decreased expression of FBN1 mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 2201 |
FBN2
CCA DA9 |
fibrillin 2 | Genistein results in decreased expression of FBN2 mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 114907 |
FBXO32
Fbx32 MAFbx |
F-box protein 32 | Genistein results in increased expression of FBXO32 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 26271 |
FBXO5
EMI1 FBX5 Fbxo31 |
F-box protein 5 | Genistein results in increased expression of FBXO5 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 2237 |
FEN1
FEN-1 MF1 RAD2 |
flap structure-specific endonuclease 1 | Genistein results in increased expression of FEN1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 2246 |
FGF1
AFGF ECGF ECGF-beta ECGFA ECGFB FGF-1 FGF-alpha FGFA GLIO703 HBGF-1 HBGF1 |
fibroblast growth factor 1 (acidic) | Genistein results in decreased expression of FGF1 mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 2263 |
FGFR2
BBDS BEK BFR-1 CD332 CEK3 CFD1 ECT1 JWS K-SAM KGFR TK14 TK25 |
fibroblast growth factor receptor 2 (EC:2.7.10.1) | ESR2 promotes the reaction [Genistein results in increased expression of FGFR2 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 2263 |
FGFR2
BBDS BEK BFR-1 CD332 CEK3 CFD1 ECT1 JWS K-SAM KGFR TK14 TK25 |
fibroblast growth factor receptor 2 (EC:2.7.10.1) | Genistein results in decreased expression of FGFR2 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 2263 |
FGFR2
BBDS BEK BFR-1 CD332 CEK3 CFD1 ECT1 JWS K-SAM KGFR TK14 TK25 |
fibroblast growth factor receptor 2 (EC:2.7.10.1) | Genistein results in increased expression of FGFR2 protein |
increases expression
|
protein |
20884965
|
| D019833 | 2274 |
FHL2
AAG11 DRAL FHL-2 SLIM-3 SLIM3 |
four and a half LIM domains 2 | ESR2 promotes the reaction [Genistein results in decreased expression of FHL2 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 2274 |
FHL2
AAG11 DRAL FHL-2 SLIM-3 SLIM3 |
four and a half LIM domains 2 | Genistein results in decreased expression of FHL2 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 2274 |
FHL2
AAG11 DRAL FHL-2 SLIM-3 SLIM3 |
four and a half LIM domains 2 | Genistein results in decreased expression of FHL2 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 2274 |
FHL2
AAG11 DRAL FHL-2 SLIM-3 SLIM3 |
four and a half LIM domains 2 | Genistein results in increased expression of FHL2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 2288 |
FKBP4
FKBP51 FKBP52 FKBP59 HBI Hsp56 PPIase p52 |
FK506 binding protein 4, 59kDa (EC:5.2.1.8) | Genistein results in increased expression of FKBP4 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 2316 |
FLNA
ABP-280 ABPX CSBS CVD1 FLN FLN-A FLN1 FMD MNS NHBP OPD OPD1 OPD2 XLVD XMVD |
filamin A, alpha | ESR2 promotes the reaction [Genistein results in decreased expression of FLNA protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 2316 |
FLNA
ABP-280 ABPX CSBS CVD1 FLN FLN-A FLN1 FMD MNS NHBP OPD OPD1 OPD2 XLVD XMVD |
filamin A, alpha | Genistein results in decreased expression of FLNA protein |
decreases expression
|
protein |
20884965
|
| D019833 | 56776 |
FMN2
|
formin 2 | [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of FMN2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
16963248
|
| D019833 | 252995 |
FNDC5
FRCP2 irisin |
fibronectin type III domain containing 5 | Genistein results in decreased expression of FNDC5 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 2348 |
FOLR1
FBP FOLR |
folate receptor 1 (adult) | Genistein results in decreased expression of FOLR1 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 2353 |
FOS
AP-1 C-FOS p55 |
FBJ murine osteosarcoma viral oncogene homolog | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased expression of FOS mRNA] |
decreases reaction
/ increases expression |
mRNA |
15090535
|
| D019833 | 2353 |
FOS
AP-1 C-FOS p55 |
FBJ murine osteosarcoma viral oncogene homolog | AG 1879 inhibits the reaction [Genistein results in increased expression of FOS protein] |
decreases reaction
/ increases expression |
protein |
15090535
|
| D019833 | 2353 |
FOS
AP-1 C-FOS p55 |
FBJ murine osteosarcoma viral oncogene homolog | Cycloheximide inhibits the reaction [Genistein results in increased expression of FOS protein] |
decreases reaction
/ increases expression |
protein |
15090535
|
| D019833 | 2353 |
FOS
AP-1 C-FOS p55 |
FBJ murine osteosarcoma viral oncogene homolog | Genistein results in increased expression of FOS mRNA |
increases expression
|
mRNA |
15090535
23019147 |
| D019833 | 2353 |
FOS
AP-1 C-FOS p55 |
FBJ murine osteosarcoma viral oncogene homolog | Genistein results in increased expression of FOS protein |
increases expression
|
protein |
15090535
|
| D019833 | 2353 |
FOS
AP-1 C-FOS p55 |
FBJ murine osteosarcoma viral oncogene homolog | GPER1 protein affects the reaction [Genistein results in increased expression of FOS protein] |
affects reaction
/ increases expression |
protein |
15090535
|
| D019833 | 2353 |
FOS
AP-1 C-FOS p55 |
FBJ murine osteosarcoma viral oncogene homolog | MAPK3 gene mutant form inhibits the reaction [Genistein results in increased expression of FOS protein] |
decreases reaction
/ increases expression |
protein |
15090535
|
| D019833 | 2353 |
FOS
AP-1 C-FOS p55 |
FBJ murine osteosarcoma viral oncogene homolog | MEN1 protein inhibits the reaction [Genistein results in increased expression of FOS mRNA] |
decreases reaction
/ increases expression |
mRNA |
15090535
|
| D019833 | 2353 |
FOS
AP-1 C-FOS p55 |
FBJ murine osteosarcoma viral oncogene homolog | Pertussis Toxin inhibits the reaction [Genistein results in increased expression of FOS protein] |
decreases reaction
/ increases expression |
protein |
15090535
|
| D019833 | 2353 |
FOS
AP-1 C-FOS p55 |
FBJ murine osteosarcoma viral oncogene homolog | tyrphostin AG 1478 inhibits the reaction [Genistein results in increased expression of FOS protein] |
decreases reaction
/ increases expression |
protein |
15090535
|
| D019833 | 2297 |
FOXD1
FKHL8 FREAC4 |
forkhead box D1 | Genistein results in increased expression of FOXD1 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 2302 |
FOXJ1
FKHL13 HFH-4 HFH4 |
forkhead box J1 | Genistein results in decreased expression of FOXJ1 mRNA |
decreases expression
|
mRNA |
16705744
19371625 |
| D019833 | 2309 |
FOXO3
AF6q21 FKHRL1 FKHRL1P2 FOXO2 FOXO3A |
forkhead box O3 | Genistein affects the expression of FOXO3 mRNA |
affects expression
|
mRNA |
18431742
|
| D019833 | 2309 |
FOXO3
AF6q21 FKHRL1 FKHRL1P2 FOXO2 FOXO3A |
forkhead box O3 | Genistein affects the expression of FOXO3 protein |
affects expression
|
protein |
18431742
|
| D019833 | 2309 |
FOXO3
AF6q21 FKHRL1 FKHRL1P2 FOXO2 FOXO3A |
forkhead box O3 | Genistein affects the localization of FOXO3 protein |
affects localization
|
protein |
18431742
|
| D019833 | 2309 |
FOXO3
AF6q21 FKHRL1 FKHRL1P2 FOXO2 FOXO3A |
forkhead box O3 | Genistein inhibits the reaction [HIST3H3 protein modified form binds to FOXO3 promoter] |
affects binding
/ decreases reaction |
promoter |
18431742
|
| D019833 | 2309 |
FOXO3
AF6q21 FKHRL1 FKHRL1P2 FOXO2 FOXO3A |
forkhead box O3 | Genistein inhibits the reaction [SIRT1 protein binds to FOXO3 promoter] |
affects binding
/ decreases reaction |
promoter |
18431742
|
| D019833 | 2309 |
FOXO3
AF6q21 FKHRL1 FKHRL1P2 FOXO2 FOXO3A |
forkhead box O3 | Genistein results in decreased phosphorylation of FOXO3 protein |
decreases phosphorylation
|
protein |
18431742
|
| D019833 | 2309 |
FOXO3
AF6q21 FKHRL1 FKHRL1P2 FOXO2 FOXO3A |
forkhead box O3 | [[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased activity of FOXO3 protein |
decreases activity
/ increases activity / increases expression |
protein |
18431742
|
| D019833 | 2525 |
FUT3
CD174 FT3B FucT-III LE Les |
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (EC:2.4.1.65) | Genistein results in increased expression of FUT3 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 2527 |
FUT5
FUC-TV |
fucosyltransferase 5 (alpha (1,3) fucosyltransferase) (EC:2.4.1.65) | Genistein results in increased expression of FUT5 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 7976 |
FZD3
Fz-3 |
frizzled family receptor 3 | Genistein results in increased expression of FZD3 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 7855 |
FZD5
C2orf31 HFZ5 |
frizzled family receptor 5 | Genistein results in increased expression of FZD5 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 50486 |
G0S2
RP1-28O10.2 |
G0/G1switch 2 | Genistein results in increased expression of G0S2 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 2548 |
GAA
LYAG |
glucosidase, alpha; acid (EC:3.2.1.20) | Genistein results in increased expression of GAA mRNA |
increases expression
|
mRNA |
16705744
|
| D019833 | 1647 |
GADD45A
DDIT1 GADD45 |
growth arrest and DNA-damage-inducible, alpha | Genistein results in decreased expression of GADD45A mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 10912 |
GADD45G
CR6 DDIT2 GADD45gamma GRP17 |
growth arrest and DNA-damage-inducible, gamma | Genistein results in increased expression of GADD45G mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 8693 |
GALNT4
GALNAC-T4 GALNACT4 |
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4) (EC:2.4.1.41) | Genistein results in increased expression of GALNT4 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 8811 |
GALR2
GAL2-R GALNR2 GALR-2 |
galanin receptor 2 | Genistein results in decreased expression of GALR2 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 2621 |
GAS6
AXLLG AXSF |
growth arrest-specific 6 | Genistein results in increased expression of GAS6 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 2633 |
GBP1
|
guanylate binding protein 1, interferon-inducible | Genistein results in decreased expression of GBP1 mRNA |
decreases expression
|
mRNA |
16705744
20884965 |
| D019833 | 2634 |
GBP2
|
guanylate binding protein 2, interferon-inducible | Genistein results in decreased expression of GBP2 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 9615 |
GDA
CYPIN GUANASE NEDASIN |
guanine deaminase (EC:3.5.4.3) | Genistein results in decreased expression of GDA mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 9518 |
GDF15
GDF-15 MIC-1 MIC1 NAG-1 PLAB PTGFB |
growth differentiation factor 15 | Genistein results in decreased expression of GDF15 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 81544 |
GDPD5
GDE2 PP1665 |
glycerophosphodiester phosphodiesterase domain containing 5 | Genistein results in increased expression of GDPD5 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 2674 |
GFRA1
GDNFR GDNFRA GFR-ALPHA-1 RET1L RETL1 TRNR1 |
GDNF family receptor alpha 1 | Genistein results in increased expression of GFRA1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 8836 |
GGH
GH |
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) (EC:3.4.19.9) | Genistein results in increased expression of GGH mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 9837 |
GINS1
PSF1 |
GINS complex subunit 1 (Psf1 homolog) | Genistein results in increased expression of GINS1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 51659 |
GINS2
HSPC037 PSF2 Pfs2 |
GINS complex subunit 2 (Psf2 homolog) | Genistein results in increased expression of GINS2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 10755 |
GIPC1
C19orf3 GIPC GLUT1CBP Hs.6454 IIP-1 NIP RGS19IP1 SEMCAP SYNECTIIN SYNECTIN TIP-2 |
GIPC PDZ domain containing family, member 1 | ESR2 promotes the reaction [Genistein results in increased expression of GIPC1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 10755 |
GIPC1
C19orf3 GIPC GLUT1CBP Hs.6454 IIP-1 NIP RGS19IP1 SEMCAP SYNECTIIN SYNECTIN TIP-2 |
GIPC PDZ domain containing family, member 1 | Genistein results in increased expression of GIPC1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 2731 |
GLDC
GCE GCSP HYGN1 |
glycine dehydrogenase (decarboxylating) (EC:1.4.4.2) | Genistein results in increased expression of GLDC mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 2741 |
GLRA1
HKPX1 STHE |
glycine receptor, alpha 1 | Genistein results in decreased activity of GLRA1 protein |
decreases activity
|
protein |
20719748
|
| D019833 | 2741 |
GLRA1
HKPX1 STHE |
glycine receptor, alpha 1 | Strychnine promotes the reaction [Genistein results in decreased activity of GLRA1 protein] |
decreases activity
/ increases reaction |
protein |
20719748
|
| D019833 | 51022 |
GLRX2
CGI-133 GRX2 |
glutaredoxin 2 | Genistein results in increased expression of GLRX2 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 2752 |
GLUL
GLNS GS PIG43 PIG59 |
glutamate-ammonia ligase (EC:4.1.1.15 6.3.1.2) | Genistein results in decreased expression of GLUL mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 51053 |
GMNN
Gem |
geminin, DNA replication inhibitor | Genistein results in increased expression of GMNN mRNA |
increases expression
|
mRNA |
15256057
16474171 |
| D019833 | 2783 |
GNB2
|
guanine nucleotide binding protein (G protein), beta polypeptide 2 | Genistein results in decreased expression of GNB2 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 2788 |
GNG7
|
guanine nucleotide binding protein (G protein), gamma 7 | Genistein results in increased expression of GNG7 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 2806 |
GOT2
KAT4 KATIV mitAAT |
glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7) | ESR2 promotes the reaction [Genistein results in increased expression of GOT2 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 2806 |
GOT2
KAT4 KATIV mitAAT |
glutamic-oxaloacetic transaminase 2, mitochondrial (EC:2.6.1.1 2.6.1.7) | Genistein results in increased expression of GOT2 protein |
increases expression
|
protein |
20884965
|
| D019833 | 2852 |
GPER1
CEPR CMKRL2 DRY12 FEG-1 GPCR-Br GPER GPR30 LERGU LERGU2 LyGPR |
G protein-coupled estrogen receptor 1 | Genistein binds to and results in increased activity of GPER1 protein |
affects binding
/ increases activity |
protein |
17088055
|
| D019833 | 2852 |
GPER1
CEPR CMKRL2 DRY12 FEG-1 GPCR-Br GPER GPR30 LERGU LERGU2 LyGPR |
G protein-coupled estrogen receptor 1 | GPER1 protein affects the reaction [Genistein results in increased expression of FOS protein] |
affects reaction
/ increases expression |
protein |
15090535
|
| D019833 | 9289 |
GPR56
BFPP TM7LN4 TM7XN1 |
G protein-coupled receptor 56 | Genistein results in increased expression of GPR56 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 9052 |
GPRC5A
GPCR5A RAI3 RAIG1 |
G protein-coupled receptor, family C, group 5, member A | Genistein results in decreased expression of GPRC5A mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 2873 |
GPS1
COPS1 CSN1 |
G protein pathway suppressor 1 | ESR2 promotes the reaction [Genistein results in decreased expression of GPS1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 2873 |
GPS1
COPS1 CSN1 |
G protein pathway suppressor 1 | Genistein results in decreased expression of GPS1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 26086 |
GPSM1
AGS3 |
G-protein signaling modulator 1 | Genistein results in increased expression of GPSM1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 2876 |
GPX1
GPXD GSHPX1 |
glutathione peroxidase 1 (EC:1.11.1.9) | Genistein results in increased expression of GPX1 mRNA |
increases expression
|
mRNA |
18686095
|
| D019833 | 2885 |
GRB2
ASH EGFRBP-GRB2 Grb3-3 MST084 MSTP084 NCKAP2 |
growth factor receptor-bound protein 2 | Genistein results in decreased expression of GRB2 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 2885 |
GRB2
ASH EGFRBP-GRB2 Grb3-3 MST084 MSTP084 NCKAP2 |
growth factor receptor-bound protein 2 | Genistein results in increased expression of GRB2 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 9687 |
GREB1
|
growth regulation by estrogen in breast cancer 1 | Genistein promotes the reaction [ESR1 protein binds to GREB1 promoter] |
affects binding
/ increases reaction |
promoter |
23019147
|
| D019833 | 9687 |
GREB1
|
growth regulation by estrogen in breast cancer 1 | Genistein results in increased expression of GREB1 mRNA |
increases expression
|
mRNA |
16474171
19371625 23019147 |
| D019833 | 2932 |
GSK3B
|
glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) | Genistein results in decreased phosphorylation of GSK3B protein |
decreases phosphorylation
|
protein |
18431742
|
| D019833 | 2936 |
GSR
|
glutathione reductase (EC:1.8.1.7) | Genistein results in decreased expression of GSR mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 2937 |
GSS
GSHS |
glutathione synthetase (EC:6.3.2.3) | Genistein results in decreased expression of GSS mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 2962 |
GTF2F1
BTF4 RAP74 TF2F1 TFIIF |
general transcription factor IIF, polypeptide 1, 74kDa | Genistein results in decreased expression of GTF2F1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 51512 |
GTSE1
B99 |
G-2 and S-phase expressed 1 | Genistein affects the expression of GTSE1 mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 3001 |
GZMA
CTLA3 HFSP |
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) (EC:3.4.21.78) | Genistein results in increased expression of GZMA mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 3005 |
H1F0
H10 H1FV |
H1 histone family, member 0 | ESR2 promotes the reaction [Genistein results in increased expression of H1F0 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3005 |
H1F0
H10 H1FV |
H1 histone family, member 0 | Genistein results in increased expression of H1F0 protein |
increases expression
|
protein |
20884965
|
| D019833 | 3014 |
H2AFX
H2A.X H2A/X H2AX |
H2A histone family, member X | Genistein results in increased expression of H2AFX mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 3015 |
H2AFZ
H2A.Z-1 H2A.z H2A/z H2AZ |
H2A histone family, member Z | ESR2 promotes the reaction [Genistein results in decreased expression of H2AFZ protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3015 |
H2AFZ
H2A.Z-1 H2A.z H2A/z H2AZ |
H2A histone family, member Z | Genistein results in decreased expression of H2AFZ protein |
decreases expression
|
protein |
20884965
|
| D019833 | 3015 |
H2AFZ
H2A.Z-1 H2A.z H2A/z H2AZ |
H2A histone family, member Z | Genistein results in increased expression of H2AFZ mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 3033 |
HADH
HAD HADH1 HADHSC HCDH HHF4 MSCHAD SCHAD |
hydroxyacyl-CoA dehydrogenase (EC:1.1.1.35) | Genistein results in increased expression of HADH mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 3036 |
HAS1
HAS |
hyaluronan synthase 1 (EC:2.4.1.212) | Genistein results in decreased expression of HAS1 mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 26959 |
HBP1
|
HMG-box transcription factor 1 | Genistein results in decreased expression of HBP1 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 54985 |
HCFC1R1
HPIP |
host cell factor C1 regulator 1 (XPO1 dependent) | Genistein results in increased expression of HCFC1R1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 610 |
HCN2
BCNG-2 BCNG2 HAC-1 |
hyperpolarization activated cyclic nucleotide-gated potassium channel 2 | Genistein results in increased expression of HCN2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 10870 |
HCST
DAP10 KAP10 PIK3AP |
hematopoietic cell signal transducer | Genistein results in decreased expression of HCST mRNA |
decreases expression
|
mRNA |
18847459
|
| D019833 | 63897 |
HEATR6
ABC1 |
HEAT repeat containing 6 | Genistein results in increased expression of HEATR6 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 3280 |
HES1
HES-1 HHL HRY bHLHb39 |
hes family bHLH transcription factor 1 | Genistein results in decreased expression of HES1 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 54626 |
HES2
bHLHb40 |
hes family bHLH transcription factor 2 | Genistein results in increased expression of HES2 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 284004 |
HEXDC
|
hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing (EC:3.2.1.52) | Genistein results in increased expression of HEXDC mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 3091 |
HIF1A
HIF-1A HIF-1alpha HIF1 HIF1-ALPHA MOP1 PASD8 bHLHe78 |
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Genistein affects the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]] |
affects binding
/ affects reaction / increases reaction |
protein |
10939628
|
| D019833 | 3091 |
HIF1A
HIF-1A HIF-1alpha HIF1 HIF1-ALPHA MOP1 PASD8 bHLHe78 |
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Genistein affects the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]] |
affects binding
/ affects reaction / increases reaction |
protein |
10939628
|
| D019833 | 3009 |
HIST1H1B
H1 H1.5 H1B H1F5 H1s-3 |
histone cluster 1, H1b | ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1B protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3009 |
HIST1H1B
H1 H1.5 H1B H1F5 H1s-3 |
histone cluster 1, H1b | Genistein results in increased expression of HIST1H1B protein |
increases expression
|
protein |
20884965
|
| D019833 | 3006 |
HIST1H1C
H1.2 H1C H1F2 H1s-1 |
histone cluster 1, H1c | ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1C protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3006 |
HIST1H1C
H1.2 H1C H1F2 H1s-1 |
histone cluster 1, H1c | Genistein results in increased expression of HIST1H1C protein |
increases expression
|
protein |
20884965
|
| D019833 | 3008 |
HIST1H1E
H1.4 H1E H1F4 H1s-4 dJ221C16.5 |
histone cluster 1, H1e | ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1E protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3008 |
HIST1H1E
H1.4 H1E H1F4 H1s-4 dJ221C16.5 |
histone cluster 1, H1e | Genistein results in increased expression of HIST1H1E protein |
increases expression
|
protein |
20884965
|
| D019833 | 8335 |
HIST1H2AB
H2A/m H2AFM |
histone cluster 1, H2ab | ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2AB protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 8335 |
HIST1H2AB
H2A/m H2AFM |
histone cluster 1, H2ab | Genistein results in increased expression of HIST1H2AB protein |
increases expression
|
protein |
20884965
|
| D019833 | 8334 |
HIST1H2AC
H2A/l H2AFL dJ221C16.4 |
histone cluster 1, H2ac | Genistein results in decreased expression of HIST1H2AC mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 8969 |
HIST1H2AG
H2A.1b H2A/p H2AFP H2AG pH2A/f |
histone cluster 1, H2ag | ESR2 promotes the reaction [Genistein results in decreased expression of HIST1H2AG protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 8969 |
HIST1H2AG
H2A.1b H2A/p H2AFP H2AG pH2A/f |
histone cluster 1, H2ag | ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2AG protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 8969 |
HIST1H2AG
H2A.1b H2A/p H2AFP H2AG pH2A/f |
histone cluster 1, H2ag | Genistein results in decreased expression of HIST1H2AG protein |
decreases expression
|
protein |
20884965
|
| D019833 | 8969 |
HIST1H2AG
H2A.1b H2A/p H2AFP H2AG pH2A/f |
histone cluster 1, H2ag | Genistein results in increased expression of HIST1H2AG protein |
increases expression
|
protein |
20884965
|
| D019833 | 3017 |
HIST1H2BD
H2B.1B H2B/b H2BFB HIRIP2 dJ221C16.6 |
histone cluster 1, H2bd | Genistein results in decreased expression of HIST1H2BD mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 8341 |
HIST1H2BN
H2B/d H2BFD |
histone cluster 1, H2bn | ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2BN protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 8341 |
HIST1H2BN
H2B/d H2BFD |
histone cluster 1, H2bn | Genistein results in increased expression of HIST1H2BN protein |
increases expression
|
protein |
20884965
|
| D019833 | 8359 |
HIST1H4A
H4FA |
histone cluster 1, H4a | ESR2 promotes the reaction [Genistein results in decreased expression of HIST1H4A protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 8359 |
HIST1H4A
H4FA |
histone cluster 1, H4a | ESR2 promotes the reaction [Genistein results in increased expression of HIST1H4A protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 8359 |
HIST1H4A
H4FA |
histone cluster 1, H4a | Genistein results in decreased expression of HIST1H4A protein |
decreases expression
|
protein |
20884965
|
| D019833 | 8359 |
HIST1H4A
H4FA |
histone cluster 1, H4a | Genistein results in increased expression of HIST1H4A protein |
increases expression
|
protein |
20884965
|
| D019833 | 8349 |
HIST2H2BE
GL105 H2B H2B.1 H2BFQ H2BGL105 H2BQ |
histone cluster 2, H2be | Genistein results in decreased expression of HIST2H2BE mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 8290 |
HIST3H3
H3.4 H3/g H3FT H3t |
histone cluster 3, H3 | Genistein inhibits the reaction [HIST3H3 protein modified form binds to CYLD promoter] |
affects binding
/ decreases reaction |
protein |
18431742
|
| D019833 | 8290 |
HIST3H3
H3.4 H3/g H3FT H3t |
histone cluster 3, H3 | Genistein inhibits the reaction [HIST3H3 protein modified form binds to FOXO3 promoter] |
affects binding
/ decreases reaction |
protein |
18431742
|
| D019833 | 8290 |
HIST3H3
H3.4 H3/g H3FT H3t |
histone cluster 3, H3 | Genistein inhibits the reaction [HIST3H3 protein modified form binds to PTEN promoter] |
affects binding
/ decreases reaction |
protein |
18431742
|
| D019833 | 8290 |
HIST3H3
H3.4 H3/g H3FT H3t |
histone cluster 3, H3 | Genistein inhibits the reaction [HIST3H3 protein modified form binds to TP53 promoter] |
affects binding
/ decreases reaction |
protein |
18431742
|
| D019833 | 8290 |
HIST3H3
H3.4 H3/g H3FT H3t |
histone cluster 3, H3 | [Genistein results in decreased activity of SIRT1 protein] which results in decreased acetylation of HIST3H3 protein |
decreases acetylation
/ decreases activity |
protein |
18431742
|
| D019833 | 8290 |
HIST3H3
H3.4 H3/g H3FT H3t |
histone cluster 3, H3 | Genistein results in increased expression of HIST3H3 protein modified form |
increases expression
|
protein |
19221000
|
| D019833 | 3096 |
HIVEP1
CIRIP CRYBP1 MBP-1 PRDII-BF1 Schnurri-1 ZAS1 ZNF40 ZNF40A |
human immunodeficiency virus type I enhancer binding protein 1 | Genistein results in increased expression of HIVEP1 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 3099 |
HK2
HKII HXK2 |
hexokinase 2 (EC:2.7.1.1) | Genistein results in increased expression of HK2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 3122 |
HLA-DRA
HLA-DRA1 MLRW |
major histocompatibility complex, class II, DR alpha | Genistein results in decreased expression of HLA-DRA mRNA |
decreases expression
|
mRNA |
20816778
|
| D019833 | 81502 |
HM13
H13 IMP1 IMPAS IMPAS-1 MSTP086 PSENL3 PSL3 SPP SPPL1 dJ324O17.1 |
histocompatibility (minor) 13 | Genistein results in decreased expression of HM13 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 3148 |
HMGB2
HMG2 |
high mobility group box 2 | Genistein results in increased expression of HMGB2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 3155 |
HMGCL
HL |
3-hydroxymethyl-3-methylglutaryl-CoA lyase (EC:4.1.3.4) | Genistein results in increased expression of HMGCL mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 3150 |
HMGN1
HMG14 |
high mobility group nucleosome binding domain 1 | ESR1 promotes the reaction [Genistein results in decreased expression of HMGN1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3150 |
HMGN1
HMG14 |
high mobility group nucleosome binding domain 1 | Genistein results in decreased expression of HMGN1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 3151 |
HMGN2
HMG17 |
high mobility group nucleosomal binding domain 2 | Genistein results in decreased expression of HMGN2 mRNA |
decreases expression
|
mRNA |
18847459
19371625 |
| D019833 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Genistein inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
9722676
|
| D019833 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Genistein inhibits the reaction [Hemin results in increased expression of HMOX1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
9722676
|
| D019833 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Genistein inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
9722676
|
| D019833 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Genistein promotes the reaction [Cadmium Chloride results in increased expression of HMOX1 protein] |
increases expression
/ increases reaction |
protein |
22659318
|
| D019833 | 3181 |
HNRNPA2B1
HNRNPA2 HNRNPB1 HNRPA2 HNRPA2B1 HNRPB1 IBMPFD2 RNPA2 SNRPB1 |
heterogeneous nuclear ribonucleoprotein A2/B1 | ESR2 promotes the reaction [Genistein results in increased expression of HNRNPA2B1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3181 |
HNRNPA2B1
HNRNPA2 HNRNPB1 HNRPA2 HNRPA2B1 HNRPB1 IBMPFD2 RNPA2 SNRPB1 |
heterogeneous nuclear ribonucleoprotein A2/B1 | Genistein results in increased expression of HNRNPA2B1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 3183 |
HNRNPC
C1 C2 HNRNP HNRPC SNRPC |
heterogeneous nuclear ribonucleoprotein C (C1/C2) | ESR1 promotes the reaction [Genistein results in decreased expression of HNRNPC protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3183 |
HNRNPC
C1 C2 HNRNP HNRPC SNRPC |
heterogeneous nuclear ribonucleoprotein C (C1/C2) | ESR2 promotes the reaction [Genistein results in decreased expression of HNRNPC protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3183 |
HNRNPC
C1 C2 HNRNP HNRPC SNRPC |
heterogeneous nuclear ribonucleoprotein C (C1/C2) | ESR2 promotes the reaction [Genistein results in increased expression of HNRNPC protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3183 |
HNRNPC
C1 C2 HNRNP HNRPC SNRPC |
heterogeneous nuclear ribonucleoprotein C (C1/C2) | Genistein results in decreased expression of HNRNPC protein |
decreases expression
|
protein |
20884965
|
| D019833 | 3183 |
HNRNPC
C1 C2 HNRNP HNRPC SNRPC |
heterogeneous nuclear ribonucleoprotein C (C1/C2) | Genistein results in increased expression of HNRNPC protein |
increases expression
|
protein |
20884965
|
| D019833 | 221092 |
HNRNPUL2
HNRPUL2 SAF-A2 |
heterogeneous nuclear ribonucleoprotein U-like 2 | ESR2 promotes the reaction [Genistein results in increased expression of HNRNPUL2 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 221092 |
HNRNPUL2
HNRPUL2 SAF-A2 |
heterogeneous nuclear ribonucleoprotein U-like 2 | Genistein results in increased expression of HNRNPUL2 protein |
increases expression
|
protein |
20884965
|
| D019833 | 9455 |
HOMER2
ACPD CPD HOMER-2 VESL-2 |
homer homolog 2 (Drosophila) | Genistein results in decreased expression of HOMER2 mRNA |
decreases expression
|
mRNA |
15378649
|
| D019833 | 3206 |
HOXA10
HOX1 HOX1.8 HOX1H PL |
homeobox A10 | Genistein results in increased expression of HOXA10 mRNA |
increases expression
|
mRNA |
16632680
|
| D019833 | 3206 |
HOXA10
HOX1 HOX1.8 HOX1H PL |
homeobox A10 | Genistein results in increased expression of HOXA10 protein |
increases expression
|
protein |
16632680
|
| D019833 | 55806 |
HR
ALUNC AU HSA277165 MUHH MUHH1 |
hair growth associated | Genistein results in increased expression of HR mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 3291 |
HSD11B2
AME AME1 HSD11K HSD2 SDR9C3 |
hydroxysteroid (11-beta) dehydrogenase 2 (EC:1.1.1.146) | Genistein results in increased expression of HSD11B2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 3292 |
HSD17B1
EDH17B2 EDHB17 HSD17 SDR28C1 |
hydroxysteroid (17-beta) dehydrogenase 1 (EC:1.1.1.62) | Genistein results in decreased activity of HSD17B1 protein |
decreases activity
|
protein |
15876411
|
| D019833 | 7923 |
HSD17B8
D6S2245E FABG FABGL H2-KE6 HKE6 KE6 RING2 SDR30C1 dJ1033B10.9 |
hydroxysteroid (17-beta) dehydrogenase 8 (EC:1.1.1.62 1.1.1.239) | ESR2 promotes the reaction [Genistein results in increased expression of HSD17B8 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 7923 |
HSD17B8
D6S2245E FABG FABGL H2-KE6 HKE6 KE6 RING2 SDR30C1 dJ1033B10.9 |
hydroxysteroid (17-beta) dehydrogenase 8 (EC:1.1.1.62 1.1.1.239) | Genistein results in increased expression of HSD17B8 protein |
increases expression
|
protein |
20884965
|
| D019833 | 3306 |
HSPA2
HSP70-2 HSP70-3 |
heat shock 70kDa protein 2 | Genistein results in increased expression of HSPA2 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 22824 |
HSPA4L
APG-1 HSPH3 Osp94 |
heat shock 70kDa protein 4-like | Genistein results in increased expression of HSPA4L mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 3313 |
HSPA9
CSA GRP-75 GRP75 HSPA9B MOT MOT2 MTHSP75 PBP74 |
heat shock 70kDa protein 9 (mortalin) | ESR2 promotes the reaction [Genistein results in increased expression of HSPA9 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3313 |
HSPA9
CSA GRP-75 GRP75 HSPA9B MOT MOT2 MTHSP75 PBP74 |
heat shock 70kDa protein 9 (mortalin) | Genistein results in increased expression of HSPA9 protein |
increases expression
|
protein |
20884965
|
| D019833 | 26353 |
HSPB8
CMT2L DHMN2 E2IG1 H11 HMN2 HMN2A HSP22 |
heat shock 22kDa protein 8 | Genistein results in increased expression of HSPB8 mRNA |
increases expression
|
mRNA |
23524099
|
| D019833 | 81888 |
HYI
HT036 |
hydroxypyruvate isomerase (putative) (EC:5.3.1.22) | Genistein results in decreased expression of HYI mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 3397 |
ID1
ID bHLHb24 |
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | Genistein results in decreased expression of ID1 mRNA |
decreases expression
|
mRNA |
21554132
23019147 |
| D019833 | 3397 |
ID1
ID bHLHb24 |
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | Genistein results in decreased expression of ID1 protein |
decreases expression
|
protein |
21554132
|
| D019833 | 3399 |
ID3
HEIR-1 bHLHb25 |
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | Genistein results in decreased expression of ID3 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 3422 |
IDI1
IPP1 IPPI1 |
isopentenyl-diphosphate delta isomerase 1 (EC:5.3.3.2) | Genistein results in increased expression of IDI1 mRNA |
increases expression
|
mRNA |
15378649
|
| D019833 | 389792 |
IER5L
bA247A12.2 |
immediate early response 5-like | Genistein results in increased expression of IER5L mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 10410 |
IFITM3
1-8U DSPA2b IP15 |
interferon induced transmembrane protein 3 | Genistein results in decreased expression of IFITM3 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 3458 |
IFNG
IFG IFI |
interferon, gamma | Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL8 mRNA] |
affects cotreatment
/ decreases reaction / increases expression |
protein |
15779068
|
| D019833 | 3458 |
IFNG
IFG IFI |
interferon, gamma | Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL8 protein] |
affects cotreatment
/ decreases reaction / increases expression |
protein |
15779068
|
| D019833 | 3458 |
IFNG
IFG IFI |
interferon, gamma | Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA] |
affects cotreatment
/ decreases reaction / increases expression |
protein |
15779068
|
| D019833 | 3458 |
IFNG
IFG IFI |
interferon, gamma | Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein] |
affects cotreatment
/ decreases reaction / increases expression |
protein |
15779068
|
| D019833 | 282618 |
IFNL1
IL-29 IL29 |
interferon, lambda 1 | Genistein results in increased expression of IFNL1 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 7866 |
IFRD2
IFNRP SKMc15 SM15 |
interferon-related developmental regulator 2 | [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of IFRD2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
16963248
|
| D019833 | 3479 |
IGF1
IGF-I IGF1A IGFI |
insulin-like growth factor 1 (somatomedin C) | Genistein results in decreased expression of IGF1 mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 3480 |
IGF1R
CD221 IGFIR IGFR JTK13 |
insulin-like growth factor 1 receptor (EC:2.7.10.1) | Genistein results in decreased expression of IGF1R mRNA |
decreases expression
|
mRNA |
16865672
|
| D019833 | 3486 |
IGFBP3
BP-53 IBP3 |
insulin-like growth factor binding protein 3 | [Calcitriol co-treated with Genistein] results in increased expression of IGFBP3 mRNA |
affects cotreatment
/ increases expression |
mRNA |
15955619
|
| D019833 | 3486 |
IGFBP3
BP-53 IBP3 |
insulin-like growth factor binding protein 3 | Genistein results in decreased expression of IGFBP3 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 3487 |
IGFBP4
BP-4 HT29-IGFBP IBP4 IGFBP-4 |
insulin-like growth factor binding protein 4 | Genistein results in increased expression of IGFBP4 mRNA |
increases expression
|
mRNA |
15757668
16474171 20884965 |
| D019833 | 93185 |
IGSF8
CD316 CD81P3 EWI-2 EWI2 KCT-4 LIR-D1 PGRL |
immunoglobulin superfamily, member 8 | Genistein results in increased expression of IGSF8 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 3600 |
IL15
IL-15 |
interleukin 15 | Genistein results in decreased expression of IL15 mRNA |
decreases expression
|
mRNA |
20816778
|
| D019833 | 3552 |
IL1A
IL-1A IL1 IL1-ALPHA IL1F1 |
interleukin 1, alpha | Genistein results in decreased expression of IL1A mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | Genistein inhibits the reaction [IL1B protein results in increased secretion of IL8 protein] |
decreases reaction
/ increases secretion |
protein |
18377686
|
| D019833 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | Genistein results in decreased expression of IL1B mRNA |
decreases expression
|
mRNA |
20816778
|
| D019833 | 7850 |
IL1R2
CD121b CDw121b IL-1R-2 IL-1RT-2 IL-1RT2 IL1R2c IL1RB |
interleukin 1 receptor, type II | Genistein results in increased expression of IL1R2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 3566 |
IL4R
CD124 IL-4RA IL4RA |
interleukin 4 receptor | Genistein results in decreased expression of IL4R mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 3566 |
IL4R
CD124 IL-4RA IL4RA |
interleukin 4 receptor | Genistein results in increased expression of IL4R mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 3569 |
IL6
BSF2 HGF HSF IFNB2 IL-6 |
interleukin 6 (interferon, beta 2) | Genistein results in decreased secretion of IL6 protein |
decreases secretion
|
protein |
20816778
|
| D019833 | 3569 |
IL6
BSF2 HGF HSF IFNB2 IL-6 |
interleukin 6 (interferon, beta 2) | Genistein results in increased expression of IL6 mRNA |
increases expression
|
mRNA |
18025290
|
| D019833 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Genistein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IL8 mRNA] |
decreases reaction
/ increases expression |
mRNA |
21056929
|
| D019833 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Genistein inhibits the reaction [IL1B protein results in increased secretion of IL8 protein] |
decreases reaction
/ increases secretion |
protein |
18377686
|
| D019833 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL8 mRNA] |
affects cotreatment
/ decreases reaction / increases expression |
mRNA |
15779068
|
| D019833 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL8 protein] |
affects cotreatment
/ decreases reaction / increases expression |
protein |
15779068
|
| D019833 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Genistein results in decreased expression of IL8 mRNA |
decreases expression
|
mRNA |
21056929
|
| D019833 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Genistein results in increased expression of IL8 mRNA |
increases expression
|
mRNA |
15257099
|
| D019833 | 3608 |
ILF2
NF45 PRO3063 |
interleukin enhancer binding factor 2 | Genistein results in increased expression of ILF2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 3609 |
ILF3
CBTF DRBF DRBP76 MMP4 MPHOSPH4 MPP4 NF-AT-90 NF110 NF110b NF90 NF90a NF90b NFAR NFAR-1 NFAR2 TCP110 TCP80 |
interleukin enhancer binding factor 3, 90kDa | Genistein results in decreased expression of ILF3 mRNA |
decreases expression
|
mRNA |
18847459
|
| D019833 | 3615 |
IMPDH2
IMPD2 IMPDH-II |
IMP (inosine 5'-monophosphate) dehydrogenase 2 (EC:1.1.1.205) | Genistein results in increased expression of IMPDH2 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 8821 |
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa (EC:3.1.3.66) | Genistein results in decreased expression of INPP4B mRNA |
decreases expression
|
mRNA |
15378649
|
| D019833 | 3638 |
INSIG1
CL-6 CL6 |
insulin induced gene 1 | Genistein results in increased expression of INSIG1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 9670 |
IPO13
IMP13 KAP13 LGL2 RANBP13 |
importin 13 | Genistein results in increased expression of IPO13 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 79711 |
IPO4
Imp4 |
importin 4 | Genistein results in increased expression of IPO4 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 10788 |
IQGAP2
|
IQ motif containing GTPase activating protein 2 | Genistein results in decreased expression of IQGAP2 mRNA |
decreases expression
|
mRNA |
15378649
|
| D019833 | 26145 |
IRF2BP1
|
interferon regulatory factor 2 binding protein 1 | [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of IRF2BP1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
16963248
|
| D019833 | 3665 |
IRF7
IRF-7H IRF7A IRF7B IRF7C IRF7H |
interferon regulatory factor 7 | Genistein results in increased expression of IRF7 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 8660 |
IRS2
IRS-2 |
insulin receptor substrate 2 | Genistein results in decreased expression of IRS2 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 9636 |
ISG15
G1P2 IFI15 IP17 UCRP hUCRP |
ISG15 ubiquitin-like modifier | ESR2 promotes the reaction [Genistein results in decreased expression of ISG15 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 9636 |
ISG15
G1P2 IFI15 IP17 UCRP hUCRP |
ISG15 ubiquitin-like modifier | Genistein results in decreased expression of ISG15 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 51477 |
ISYNA1
INO1 INOS IPS IPS_1 IPS-1 |
inositol-3-phosphate synthase 1 (EC:5.5.1.4) | ESR2 promotes the reaction [Genistein results in decreased expression of ISYNA1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 51477 |
ISYNA1
INO1 INOS IPS IPS_1 IPS-1 |
inositol-3-phosphate synthase 1 (EC:5.5.1.4) | ESR2 promotes the reaction [Genistein results in increased expression of ISYNA1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 51477 |
ISYNA1
INO1 INOS IPS IPS_1 IPS-1 |
inositol-3-phosphate synthase 1 (EC:5.5.1.4) | Genistein results in decreased expression of ISYNA1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 51477 |
ISYNA1
INO1 INOS IPS IPS_1 IPS-1 |
inositol-3-phosphate synthase 1 (EC:5.5.1.4) | Genistein results in increased expression of ISYNA1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 3685 |
ITGAV
CD51 MSK8 VNRA VTNR |
integrin, alpha V | ESR2 promotes the reaction [Genistein results in decreased expression of ITGAV protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3685 |
ITGAV
CD51 MSK8 VNRA VTNR |
integrin, alpha V | Genistein results in decreased expression of ITGAV protein |
decreases expression
|
protein |
20884965
|
| D019833 | 3690 |
ITGB3
BDPLT16 BDPLT2 CD61 GP3A GPIIIa GT |
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | Genistein results in decreased expression of ITGB3 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 3694 |
ITGB6
|
integrin, beta 6 | Genistein results in decreased expression of ITGB6 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 3705 |
ITPK1
ITRPK1 |
inositol-tetrakisphosphate 1-kinase (EC:2.7.1.134 2.7.1.159) | Genistein results in increased expression of ITPK1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 3708 |
ITPR1
INSP3R1 IP3R IP3R1 SCA15 SCA16 SCA29 |
inositol 1,4,5-trisphosphate receptor, type 1 | Genistein results in increased expression of ITPR1 mRNA |
increases expression
|
mRNA |
18444173
18847459 |
| D019833 | 3725 |
JUN
AP-1 AP1 c-Jun |
jun proto-oncogene | Genistein results in increased activity of JUN protein |
increases activity
|
protein |
17088408
|
| D019833 | 3725 |
JUN
AP-1 AP1 c-Jun |
jun proto-oncogene | Genistein results in increased expression of JUN mRNA |
increases expression
|
mRNA |
17266178
|
| D019833 | 3727 |
JUND
AP-1 |
jun D proto-oncogene | Genistein promotes the reaction [ESR1 protein binds to JUND promoter] |
affects binding
/ increases reaction |
promoter |
23019147
|
| D019833 | 3728 |
JUP
ARVD12 CTNNG DP3 DPIII PDGB PKGB |
junction plakoglobin | Genistein results in decreased expression of JUP mRNA |
decreases expression
|
mRNA |
16474171
16705744 |
| D019833 | 23254 |
KAZN
KAZ |
kazrin, periplakin interacting protein | Genistein results in increased expression of KAZN mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 3754 |
KCNF1
IK8 KCNF KV5.1 kH1 |
potassium voltage-gated channel, subfamily F, member 1 | Genistein results in increased expression of KCNF1 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 26251 |
KCNG2
KCNF2 KV6.2 |
potassium voltage-gated channel, subfamily G, member 2 | [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of KCNG2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
16963248
|
| D019833 | 3762 |
KCNJ5
CIR GIRK4 KATP1 KIR3.4 LQT13 |
potassium inwardly-rectifying channel, subfamily J, member 5 | Genistein results in increased expression of KCNJ5 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 60598 |
KCNK15
K2p15.1 KCNK11 KCNK14 KT3.3 TASK-5 TASK5 dJ781B1.1 |
potassium channel, subfamily K, member 15 | Genistein results in increased expression of KCNK15 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 23510 |
KCTD2
|
potassium channel tetramerization domain containing 2 | Genistein results in decreased expression of KCTD2 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 222658 |
KCTD20
C6orf69 dJ108K11.3 |
potassium channel tetramerization domain containing 20 | Genistein results in increased expression of KCTD20 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 10945 |
KDELR1
ERD2 ERD2.1 HDEL PM23 |
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | Genistein results in decreased expression of KDELR1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 9768 |
NS5ATP9
OEATC OEATC-1 OEATC1 PAF PAF15 p15(PAF) p15/PAF p15PAF |
KIAA0101 | Genistein results in decreased expression of KIAA0101 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 9768 |
NS5ATP9
OEATC OEATC-1 OEATC1 PAF PAF15 p15(PAF) p15/PAF p15PAF |
KIAA0101 | Genistein results in increased expression of KIAA0101 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 282442 | Genistein results in decreased expression of KIAA0256 mRNA |
decreases expression
|
mRNA |
16474171
|
||
| D019833 | 9851 | KIAA0753 | ESR2 promotes the reaction [Genistein results in increased expression of KIAA0753 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
|
| D019833 | 9851 | KIAA0753 | Genistein results in increased expression of KIAA0753 protein |
increases expression
|
protein |
20884965
|
|
| D019833 | 23285 | KIAA1107 | ESR2 promotes the reaction [Genistein results in increased expression of KIAA1107 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
|
| D019833 | 23285 | KIAA1107 | Genistein results in increased expression of KIAA1107 protein |
increases expression
|
protein |
20884965
|
|
| D019833 | 57648 | KIAA1522 | Genistein results in decreased expression of KIAA1522 mRNA |
decreases expression
|
mRNA |
16705744
|
|
| D019833 | 3832 |
KIF11
EG5 HKSP KNSL1 MCLMR TRIP5 |
kinesin family member 11 | Genistein results in increased expression of KIF11 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 9928 |
KIF14
|
kinesin family member 14 | Genistein results in increased expression of KIF14 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 56992 |
KIF15
HKLP2 KNSL7 NY-BR-62 |
kinesin family member 15 | Genistein results in increased expression of KIF15 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 10112 |
KIF20A
MKLP2 RAB6KIFL |
kinesin family member 20A | Genistein results in increased expression of KIF20A mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 9493 |
KIF23
CHO1 KNSL5 MKLP-1 MKLP1 |
kinesin family member 23 | Genistein results in increased expression of KIF23 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 11004 |
KIF2C
KNSL6 MCAK |
kinesin family member 2C | Genistein affects the expression of KIF2C mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 24137 |
KIF4A
KIF4 KIF4G1 |
kinesin family member 4A | Genistein results in increased expression of KIF4A mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 9365 |
KL
|
klotho (EC:3.2.1.31) | Genistein results in decreased expression of KL mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 54800 |
KLHL24
DRE1 KRIP6 |
kelch-like family member 24 | Genistein results in increased expression of KLHL24 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 3817 |
KLK2
KLK2A2 hGK-1 hK2 |
kallikrein-related peptidase 2 (EC:3.4.21.35) | Genistein results in decreased expression of KLK2 mRNA |
decreases expression
|
mRNA |
15378649
|
| D019833 | 354 |
KLK3
APS KLK2A1 PSA hK3 |
kallikrein-related peptidase 3 (EC:3.4.21.77) | Genistein results in decreased expression of KLK3 mRNA |
decreases expression
|
mRNA |
15378649
16865672 |
| D019833 | 354 |
KLK3
APS KLK2A1 PSA hK3 |
kallikrein-related peptidase 3 (EC:3.4.21.77) | Genistein results in increased expression of KLK3 mRNA |
increases expression
|
mRNA |
12391264
|
| D019833 | 4297 |
KMT2A
ALL-1 CXXC7 HRX HTRX1 MLL MLL/GAS7 MLL1A TET1-MLL TRX1 WDSTS |
lysine (K)-specific methyltransferase 2A (EC:2.1.1.43) | Genistein results in increased mutagenesis of KMT2A gene |
increases mutagenesis
|
gene |
17468513
|
| D019833 | 3838 |
KPNA2
IPOA1 QIP2 RCH1 SRP1alpha |
karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | Genistein results in increased expression of KPNA2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 448834 |
KPRP
C1orf45 |
keratinocyte proline-rich protein | ESR1 promotes the reaction [Genistein results in decreased expression of KPRP protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 448834 |
KPRP
C1orf45 |
keratinocyte proline-rich protein | Genistein results in decreased expression of KPRP protein |
decreases expression
|
protein |
20884965
|
| D019833 | 3845 |
KRAS
C-K-RAS CFC2 K-RAS2A K-RAS2B K-RAS4A K-RAS4B KI-RAS KRAS1 KRAS2 NS NS3 RASK2 |
Kirsten rat sarcoma viral oncogene homolog | Genistein results in decreased expression of KRAS mRNA |
decreases expression
|
mRNA |
15256057
16474171 |
| D019833 | 3872 |
KRT17
K17 PC PC2 PCHC1 |
keratin 17 | Genistein results in decreased expression of KRT17 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 3875 |
KRT18
CYK18 K18 |
keratin 18 | ESR1 promotes the reaction [Genistein results in increased expression of KRT18 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3875 |
KRT18
CYK18 K18 |
keratin 18 | ESR2 promotes the reaction [Genistein results in increased expression of KRT18 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3875 |
KRT18
CYK18 K18 |
keratin 18 | Genistein results in increased expression of KRT18 protein |
increases expression
|
protein |
20884965
|
| D019833 | 3880 |
KRT19
CK19 K19 K1CS |
keratin 19 | ESR1 promotes the reaction [Genistein results in increased expression of KRT19 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3880 |
KRT19
CK19 K19 K1CS |
keratin 19 | ESR2 promotes the reaction [Genistein results in increased expression of KRT19 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3880 |
KRT19
CK19 K19 K1CS |
keratin 19 | Genistein results in increased expression of KRT19 protein |
increases expression
|
protein |
20884965
|
| D019833 | 25984 |
KRT23
CK23 HAIK1 K23 |
keratin 23 (histone deacetylase inducible) | Genistein results in decreased expression of KRT23 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 3885 |
KRT34
HA4 Ha-4 KRTHA4 hHa4 |
keratin 34 | Genistein results in decreased expression of KRT34 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 3852 |
KRT5
CK5 DDD DDD1 EBS2 K5 KRT5A |
keratin 5 | Genistein results in decreased expression of KRT5 mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 3856 |
KRT8
CARD2 CK-8 CK8 CYK8 K2C8 K8 KO |
keratin 8 | ESR1 promotes the reaction [Genistein results in increased expression of KRT8 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3856 |
KRT8
CARD2 CK-8 CK8 CYK8 K2C8 K8 KO |
keratin 8 | ESR2 promotes the reaction [Genistein results in increased expression of KRT8 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3856 |
KRT8
CARD2 CK-8 CK8 CYK8 K2C8 K8 KO |
keratin 8 | Genistein results in decreased expression of KRT8 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 3856 |
KRT8
CARD2 CK-8 CK8 CYK8 K2C8 K8 KO |
keratin 8 | Genistein results in increased expression of KRT8 protein |
increases expression
|
protein |
20884965
|
| D019833 | 90133 | Genistein results in decreased expression of KRT8P12 mRNA |
decreases expression
|
mRNA |
16705744
|
||
| D019833 | 728279 |
KRTAP2-2
KAP2.2 |
keratin associated protein 2-2 | Genistein results in decreased expression of KRTAP2-2 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 85294 |
KRTAP2-4
KAP2.1B KAP2.4 KRTAP2.4 |
keratin associated protein 2-4 | Genistein results in decreased expression of KRTAP2-4 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 3897 |
L1CAM
CAML1 CD171 HSAS HSAS1 MASA MIC5 N-CAM-L1 N-CAML1 NCAM-L1 S10 SPG1 |
L1 cell adhesion molecule | Genistein results in decreased expression of L1CAM mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 3915 |
LAMC1
LAMB2 |
laminin, gamma 1 (formerly LAMB2) | Genistein results in decreased expression of LAMC1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 3920 |
LAMP2
CD107b LAMP-2 LAMPB LGP110 |
lysosomal-associated membrane protein 2 | ESR2 promotes the reaction [Genistein results in increased expression of LAMP2 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3920 |
LAMP2
CD107b LAMP-2 LAMPB LGP110 |
lysosomal-associated membrane protein 2 | Genistein results in increased expression of LAMP2 protein |
increases expression
|
protein |
20884965
|
| D019833 | 3945 |
LDHB
LDH-B LDH-H LDHBD TRG-5 |
lactate dehydrogenase B (EC:1.1.1.27) | ESR2 promotes the reaction [Genistein results in decreased expression of LDHB protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3945 |
LDHB
LDH-B LDH-H LDHBD TRG-5 |
lactate dehydrogenase B (EC:1.1.1.27) | Genistein results in decreased expression of LDHB protein |
decreases expression
|
protein |
20884965
|
| D019833 | 7044 |
LEFTY2
EBAF LEFTA LEFTYA TGFB4 |
left-right determination factor 2 | Genistein results in decreased expression of LEFTY2 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 93273 |
LEMD1
CT50 LEMP-1 |
LEM domain containing 1 | Genistein results in increased expression of LEMD1 mRNA |
increases expression
|
mRNA |
16705744
|
| D019833 | 3952 |
LEP
LEPD OB OBS |
leptin | Genistein inhibits the reaction [LEP protein results in increased chemical synthesis of Reactive Oxygen Species] |
decreases reaction
/ increases chemical synthesis |
protein |
11342529
|
| D019833 | 3952 |
LEP
LEPD OB OBS |
leptin | Genistein inhibits the reaction [LEP protein results in increased expression of CCL2] |
decreases reaction
/ increases expression |
protein |
11342529
|
| D019833 | 3952 |
LEP
LEPD OB OBS |
leptin | Genistein results in decreased susceptibility to LEP protein |
decreases response to substance
|
protein |
11342529
|
| D019833 | 3955 |
LFNG
SCDO3 |
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (EC:2.4.1.222) | Genistein results in increased expression of LFNG mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 3956 |
LGALS1
GAL1 GBP |
lectin, galactoside-binding, soluble, 1 | Genistein results in decreased expression of LGALS1 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 3963 |
LGALS7
GAL7 LGALS7A |
lectin, galactoside-binding, soluble, 7 | ESR1 promotes the reaction [Genistein results in decreased expression of LGALS7 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3963 |
LGALS7
GAL7 LGALS7A |
lectin, galactoside-binding, soluble, 7 | Genistein results in decreased expression of LGALS7 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 3980 |
LIG3
LIG2 |
ligase III, DNA, ATP-dependent (EC:6.5.1.1) | Genistein results in decreased expression of LIG3 mRNA |
decreases expression
|
mRNA |
15257099
|
| D019833 | 4000 |
LMNA
CDCD1 CDDC CMD1A CMT2B1 EMD2 FPL FPLD FPLD2 HGPS IDC LDP1 LFP LGMD1B LMN1 LMNC LMNL1 PRO1 |
lamin A/C | ESR1 promotes the reaction [Genistein results in decreased expression of LMNA protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4000 |
LMNA
CDCD1 CDDC CMD1A CMT2B1 EMD2 FPL FPLD FPLD2 HGPS IDC LDP1 LFP LGMD1B LMN1 LMNC LMNL1 PRO1 |
lamin A/C | ESR2 promotes the reaction [Genistein results in decreased expression of LMNA protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4000 |
LMNA
CDCD1 CDDC CMD1A CMT2B1 EMD2 FPL FPLD FPLD2 HGPS IDC LDP1 LFP LGMD1B LMN1 LMNC LMNL1 PRO1 |
lamin A/C | ESR2 promotes the reaction [Genistein results in increased expression of LMNA protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4000 |
LMNA
CDCD1 CDDC CMD1A CMT2B1 EMD2 FPL FPLD FPLD2 HGPS IDC LDP1 LFP LGMD1B LMN1 LMNC LMNL1 PRO1 |
lamin A/C | Genistein results in decreased expression of LMNA protein |
decreases expression
|
protein |
20884965
|
| D019833 | 4000 |
LMNA
CDCD1 CDDC CMD1A CMT2B1 EMD2 FPL FPLD FPLD2 HGPS IDC LDP1 LFP LGMD1B LMN1 LMNC LMNL1 PRO1 |
lamin A/C | Genistein results in increased expression of LMNA protein |
increases expression
|
protein |
20884965
|
| D019833 | 4001 |
LMNB1
ADLD LMN LMN2 LMNB |
lamin B1 | ESR1 promotes the reaction [Genistein results in decreased expression of LMNB1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4001 |
LMNB1
ADLD LMN LMN2 LMNB |
lamin B1 | Genistein results in decreased expression of LMNB1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 84823 |
LMNB2
LAMB2 LMN2 |
lamin B2 | ESR2 promotes the reaction [Genistein results in decreased expression of LMNB2 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 84823 |
LMNB2
LAMB2 LMN2 |
lamin B2 | Genistein results in decreased expression of LMNB2 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 9170 |
LPAR2
EDG-4 EDG4 LPA-2 LPA2 |
lysophosphatidic acid receptor 2 | Genistein results in decreased expression of LPAR2 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 4026 |
LPP
|
LIM domain containing preferred translocation partner in lipoma | ESR1 promotes the reaction [Genistein results in decreased expression of LPP protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4026 |
LPP
|
LIM domain containing preferred translocation partner in lipoma | Genistein results in decreased expression of LPP protein |
decreases expression
|
protein |
20884965
|
| D019833 | 64748 |
LPPR2
PRG4 |
lipid phosphate phosphatase-related protein type 2 (EC:3.1.3.4) | Genistein results in increased expression of LPPR2 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 91355 |
LRP5L
|
low density lipoprotein receptor-related protein 5-like | Genistein results in increased expression of LRP5L mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 7804 |
LRP8
APOER2 HSZ75190 LRP-8 MCI1 |
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | Genistein results in increased expression of LRP8 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 131578 |
LRRC15
LIB |
leucine rich repeat containing 15 | Genistein results in increased expression of LRRC15 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 4057 |
LTF
GIG12 HLF2 LF |
lactotransferrin | [Genistein co-treated with ESR1 protein] results in increased expression of LTF mRNA |
affects cotreatment
/ increases expression |
mRNA |
21783566
|
| D019833 | 4057 |
LTF
GIG12 HLF2 LF |
lactotransferrin | [Genistein co-treated with ESR2 protein] results in increased expression of LTF mRNA |
affects cotreatment
/ increases expression |
mRNA |
21783566
|
| D019833 | 56925 |
LXN
ECI TCI |
latexin | Genistein results in decreased expression of LXN mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 90624 |
LYRM7
C5orf31 MZM1L |
LYR motif containing 7 | ESR2 promotes the reaction [Genistein results in increased expression of LYRM7 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 90624 |
LYRM7
C5orf31 MZM1L |
LYR motif containing 7 | Genistein results in increased expression of LYRM7 protein |
increases expression
|
protein |
20884965
|
| D019833 | 8379 |
MAD1L1
MAD1 PIG9 TP53I9 TXBP181 |
MAD1 mitotic arrest deficient-like 1 (yeast) | Genistein results in increased expression of MAD1L1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 8567 |
MADD
DENN IG20 RAB3GEP |
MAP-kinase activating death domain | Genistein results in decreased expression of MADD mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 4094 |
MAF
CCA4 c-MAF |
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | Genistein results in decreased expression of MAF mRNA |
decreases expression
|
mRNA |
15378649
|
| D019833 | 9935 |
MAFB
KRML MCTO |
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | Genistein results in increased expression of MAFB mRNA |
increases expression
|
mRNA |
18847459
20884965 |
| D019833 | 23764 |
MAFF
U-MAF hMafF |
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | Genistein results in decreased expression of MAFF mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 28986 |
MAGEH1
APR-1 APR1 MAGEH |
melanoma antigen family H, 1 | Genistein results in increased expression of MAGEH1 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 4128 |
MAOA
MAO-A |
monoamine oxidase A (EC:1.4.3.4) | Genistein results in increased expression of MAOA mRNA |
increases expression
|
mRNA |
11331657
|
| D019833 | 5604 |
MAP2K1
CFC3 MAPKK1 MEK1 MKK1 PRKMK1 |
mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) | Genistein results in increased phosphorylation of MAP2K1 protein |
increases phosphorylation
|
protein |
19038232
|
| D019833 | 5605 |
MAP2K2
CFC4 MAPKK2 MEK2 MKK2 PRKMK2 |
mitogen-activated protein kinase kinase 2 (EC:2.7.12.2) | Genistein results in increased phosphorylation of MAP2K2 protein |
increases phosphorylation
|
protein |
19038232
|
| D019833 | 5606 |
MAP2K3
MAPKK3 MEK3 MKK3 PRKMK3 SAPKK-2 SAPKK2 |
mitogen-activated protein kinase kinase 3 (EC:2.7.12.2) | Genistein results in decreased expression of MAP2K3 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 4134 |
MAP4
|
microtubule-associated protein 4 | ESR1 promotes the reaction [Genistein results in decreased expression of MAP4 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4134 |
MAP4
|
microtubule-associated protein 4 | ESR2 promotes the reaction [Genistein results in decreased expression of MAP4 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4134 |
MAP4
|
microtubule-associated protein 4 | Genistein results in decreased expression of MAP4 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 4134 |
MAP4
|
microtubule-associated protein 4 | Genistein results in decreased expression of MAP4 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | [1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester co-treated with Genistein] inhibits the reaction [Thapsigargin promotes the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]] |
affects cotreatment
/ decreases reaction / increases phosphorylation / increases reaction |
protein |
16251475
|
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of MAPK1 protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of MAPK1 protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | AG 1879 inhibits the reaction [Genistein results in increased phosphorylation of MAPK1 protein] |
decreases reaction
/ increases phosphorylation |
protein |
16840783
|
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | Genistein inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein] |
decreases reaction
/ increases phosphorylation |
protein |
16251475
|
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | Genistein inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased phosphorylation of MAPK1 protein] |
affects localization
/ decreases reaction / increases phosphorylation |
protein |
10653605
|
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | Genistein inhibits the reaction [Thapsigargin promotes the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]] |
decreases reaction
/ increases phosphorylation / increases reaction |
protein |
16251475
|
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | Genistein results in increased activity of and results in increased phosphorylation of MAPK1 protein |
increases activity
/ increases phosphorylation |
protein |
19427779
|
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | Genistein results in increased expression of and results in increased phosphorylation of MAPK1 protein |
increases expression
/ increases phosphorylation |
protein |
16149052
|
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | Genistein results in increased phosphorylation of and results in increased activity of MAPK1 protein |
increases activity
/ increases phosphorylation |
protein |
15090535
|
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | Genistein results in increased phosphorylation of MAPK1 protein |
increases phosphorylation
|
protein |
16840783
17088408 19038232 19720055 |
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | [Tretinoin co-treated with Genistein] results in increased phosphorylation of MAPK1 protein |
affects cotreatment
/ increases phosphorylation |
protein |
16149052
|
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | U 0126 inhibits the reaction [Genistein results in increased activity of and results in increased phosphorylation of MAPK1 protein] |
decreases reaction
/ increases activity / increases phosphorylation |
protein |
19427779
|
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | U 0126 inhibits the reaction [Genistein results in increased phosphorylation of MAPK1 protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | [U 0126 results in decreased phosphorylation of [MAPK1 protein co-treated with MAPK3 protein]] which results in decreased susceptibility to Genistein |
affects cotreatment
/ decreases phosphorylation / decreases response to substance |
protein |
19427779
|
| D019833 | 5600 |
MAPK11
P38B P38BETA2 PRKM11 SAPK2 SAPK2B p38-2 p38Beta |
mitogen-activated protein kinase 11 (EC:2.7.11.24) | Genistein results in decreased phosphorylation of MAPK11 protein |
decreases phosphorylation
|
protein |
19497411
|
| D019833 | 5603 |
MAPK13
MAPK_13 MAPK-13 PRKM13 SAPK4 p38delta |
mitogen-activated protein kinase 13 (EC:2.7.11.24) | Genistein results in decreased expression of MAPK13 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | [1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester co-treated with Genistein] inhibits the reaction [Thapsigargin promotes the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein]] |
affects cotreatment
/ decreases reaction / increases phosphorylation / increases reaction |
protein |
16251475
|
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of MAPK3 protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of MAPK3 protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | AG 1879 inhibits the reaction [Genistein results in increased phosphorylation of MAPK3 protein] |
decreases reaction
/ increases phosphorylation |
protein |
16840783
|
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | Genistein inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein] |
decreases reaction
/ increases phosphorylation |
protein |
16251475
|
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | Genistein inhibits the reaction [Thapsigargin promotes the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein]] |
decreases reaction
/ increases phosphorylation / increases reaction |
protein |
16251475
|
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | Genistein results in increased activity of and results in increased phosphorylation of MAPK3 protein |
increases activity
/ increases phosphorylation |
protein |
19427779
|
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | Genistein results in increased expression of and results in increased phosphorylation of MAPK3 protein |
increases expression
/ increases phosphorylation |
protein |
16149052
|
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | Genistein results in increased phosphorylation of and results in increased activity of MAPK3 protein |
increases activity
/ increases phosphorylation |
protein |
15090535
|
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | Genistein results in increased phosphorylation of MAPK3 protein |
increases phosphorylation
|
protein |
16840783
17088408 19038232 19720055 |
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | MAPK3 gene mutant form inhibits the reaction [Genistein results in increased expression of FOS protein] |
decreases reaction
/ increases expression |
gene |
15090535
|
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | [Tretinoin co-treated with Genistein] results in increased phosphorylation of MAPK3 protein |
affects cotreatment
/ increases phosphorylation |
protein |
16149052
|
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | U 0126 inhibits the reaction [Genistein results in increased activity of and results in increased phosphorylation of MAPK3 protein] |
decreases reaction
/ increases activity / increases phosphorylation |
protein |
19427779
|
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | U 0126 inhibits the reaction [Genistein results in increased phosphorylation of MAPK3 protein] |
decreases reaction
/ increases phosphorylation |
protein |
19038232
|
| D019833 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | [U 0126 results in decreased phosphorylation of [MAPK1 protein co-treated with MAPK3 protein]] which results in decreased susceptibility to Genistein |
affects cotreatment
/ decreases phosphorylation / decreases response to substance |
protein |
19427779
|
| D019833 | 84930 |
MASTL
GREATWALL GW GWL MAST-L RP11-85G18.2 THC2 hGWL |
microtubule associated serine/threonine kinase-like (EC:2.7.11.1) | Genistein results in increased expression of MASTL mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 4145 |
MATK
CHK CTK HHYLTK HYL HYLTK Lsk |
megakaryocyte-associated tyrosine kinase (EC:2.7.10.2) | Genistein results in increased expression of MATK mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 9782 |
MATR3
MPD2 VCPDM |
matrin 3 | ESR2 promotes the reaction [Genistein results in decreased expression of MATR3 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 9782 |
MATR3
MPD2 VCPDM |
matrin 3 | ESR2 promotes the reaction [Genistein results in increased expression of MATR3 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 9782 |
MATR3
MPD2 VCPDM |
matrin 3 | Genistein results in decreased expression of MATR3 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 9782 |
MATR3
MPD2 VCPDM |
matrin 3 | Genistein results in increased expression of MATR3 protein |
increases expression
|
protein |
20884965
|
| D019833 | 4150 |
MAZ
PUR1 Pur-1 SAF-1 SAF-2 SAF-3 ZF87 ZNF801 Zif87 |
MYC-associated zinc finger protein (purine-binding transcription factor) | Genistein results in decreased expression of MAZ mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 8932 |
MBD2
DMTase NY-CO-41 |
methyl-CpG binding domain protein 2 | Genistein results in decreased activity of MBD2 protein |
decreases activity
|
protein |
19221000
|
| D019833 | 4157 |
MC1R
CMM5 MSH-R SHEP2 |
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) | Genistein results in decreased expression of MC1R mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 55388 |
MCM10
CNA43 DNA43 |
minichromosome maintenance complex component 10 | Genistein results in increased expression of MCM10 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 4171 |
MCM2
BM28 CCNL1 CDCL1 D3S3194 MITOTIN cdc19 |
minichromosome maintenance complex component 2 (EC:3.6.4.12) | Genistein results in increased expression of MCM2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 4175 |
MCM6
MCG40308 Mis5 P105MCM |
minichromosome maintenance complex component 6 (EC:3.6.4.12) | Genistein results in increased expression of MCM6 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 4176 |
MCM7
CDC47 MCM2 P1.1-MCM3 P1CDC47 P85MCM PNAS146 |
minichromosome maintenance complex component 7 (EC:3.6.4.12) | Genistein results in increased expression of MCM7 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 9656 |
MDC1
NFBD1 |
mediator of DNA-damage checkpoint 1 | Genistein results in increased expression of MDC1 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 4192 |
MDK
ARAP MK NEGF2 |
midkine (neurite growth-promoting factor 2) | Genistein results in decreased expression of MDK mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 4199 |
ME1
HUMNDME MES |
malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40) | Genistein results in increased expression of ME1 mRNA |
increases expression
|
mRNA |
16865672
|
| D019833 | 4204 |
MECP2
AUTSX3 MRX16 MRX79 MRXS13 MRXSL PPMX RS RTS RTT |
methyl CpG binding protein 2 (Rett syndrome) | Genistein results in increased expression of MECP2 mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 9282 |
MED14
CRSP150 CRSP2 CSRP CXorf4 DRIP150 EXLM1 RGR1 TRAP170 |
mediator complex subunit 14 | Genistein results in decreased expression of MED14 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 9477 |
MED20
PRO0213 TRFP |
mediator complex subunit 20 | Genistein results in decreased expression of MED20 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 9833 |
MELK
HPK38 |
maternal embryonic leucine zipper kinase (EC:2.7.11.1 2.7.10.2) | Genistein results in increased expression of MELK mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 4221 |
MEN1
MEAI SCG2 |
multiple endocrine neoplasia I | MEN1 protein inhibits the reaction [Genistein results in increased expression of FOS mRNA] |
decreases reaction
/ increases expression |
protein |
15090535
|
| D019833 | 4222 |
MEOX1
KFS2 MOX1 |
mesenchyme homeobox 1 | Genistein results in decreased expression of MEOX1 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 4233 |
MET
AUTS9 HGFR RCCP2 c-Met |
met proto-oncogene (EC:2.7.10.1) | Genistein results in increased expression of MET mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 25840 |
METTL7A
AAM-B |
methyltransferase like 7A | ESR2 promotes the reaction [Genistein results in increased expression of METTL7A protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 25840 |
METTL7A
AAM-B |
methyltransferase like 7A | Genistein results in decreased expression of METTL7A mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 25840 |
METTL7A
AAM-B |
methyltransferase like 7A | Genistein results in increased expression of METTL7A protein |
increases expression
|
protein |
20884965
|
| D019833 | 4240 |
MFGE8
BA46 EDIL1 HMFG HsT19888 MFG-E8 MFGM OAcGD3S SED1 SPAG10 hP47 |
milk fat globule-EGF factor 8 protein | Genistein results in decreased expression of MFGE8 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 9927 |
MFN2
CMT2A CMT2A2 CPRP1 HSG MARF |
mitofusin 2 | Genistein results in increased expression of MFN2 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 4242 |
MFNG
|
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (EC:2.4.1.222) | Genistein results in increased expression of MFNG mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 4255 |
MGMT
|
O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) | Genistein results in increased expression of MGMT mRNA |
increases expression
|
mRNA |
15703815
|
| D019833 | 4256 |
MGP
MGLAP NTI |
matrix Gla protein | ESR1 promotes the reaction [Genistein results in increased expression of MGP protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4256 |
MGP
MGLAP NTI |
matrix Gla protein | ESR2 promotes the reaction [Genistein results in increased expression of MGP protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4256 |
MGP
MGLAP NTI |
matrix Gla protein | Genistein results in increased expression of MGP protein |
increases expression
|
protein |
20884965
|
| D019833 | 574449 |
MIR492
MIRN492 hsa-mir-492 |
microRNA 492 | Genistein results in decreased expression of MIR492 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 724033 |
MIR663A
MIR663 MIRN663 hsa-mir-663 hsa-mir-663a |
microRNA 663a | Genistein results in increased expression of MIR663A mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 4291 |
MLF1
|
myeloid leukemia factor 1 | Genistein results in increased expression of MLF1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 79682 |
CENPU
CENP50 CENPU50 KLIP1 MLF1IP PBIP1 |
centromere protein U | Genistein results in increased expression of MLF1IP mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 197259 |
MLKL
|
mixed lineage kinase domain-like | Genistein results in decreased expression of MLKL mRNA |
decreases expression
|
mRNA |
18847459
|
| D019833 | 4301 |
MLLT4
AF6 RP3-431P23.3 |
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | Genistein results in decreased expression of MLLT4 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 79083 |
MLPH
SLAC2-A |
melanophilin | Genistein results in increased expression of MLPH mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 4312 |
MMP1
CLG CLGN |
matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) | Genistein inhibits the reaction [Chromium results in increased expression of MMP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15878362
|
| D019833 | 4312 |
MMP1
CLG CLGN |
matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) | Genistein inhibits the reaction [Cobalt results in increased expression of MMP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15878362
|
| D019833 | 4312 |
MMP1
CLG CLGN |
matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) | Genistein inhibits the reaction [Phosphorylcholine analog results in increased expression of MMP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15878362
|
| D019833 | 4323 |
MMP14
MMP-14 MMP-X1 MT-MMP MT-MMP_1 MT1-MMP MT1MMP MTMMP1 WNCHRS |
matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80) | Genistein results in decreased expression of MMP14 mRNA |
decreases expression
|
mRNA |
15754008
|
| D019833 | 4323 |
MMP14
MMP-14 MMP-X1 MT-MMP MT-MMP_1 MT1-MMP MT1MMP MTMMP1 WNCHRS |
matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80) | Genistein results in decreased expression of MMP14 protein |
decreases expression
|
protein |
16598420
|
| D019833 | 4324 |
MMP15
MT2-MMP MTMMP2 SMCP-2 |
matrix metallopeptidase 15 (membrane-inserted) (EC:3.4.24.-) | Genistein results in decreased expression of MMP15 mRNA |
decreases expression
|
mRNA |
15754008
|
| D019833 | 4325 |
MMP16
C8orf57 MMP-X2 MT-MMP2 MT-MMP3 MT3-MMP |
matrix metallopeptidase 16 (membrane-inserted) (EC:3.4.24.-) | Genistein results in decreased expression of MMP16 mRNA |
decreases expression
|
mRNA |
15754008
|
| D019833 | 4326 |
MMP17
MT4-MMP |
matrix metallopeptidase 17 (membrane-inserted) (EC:3.4.24.-) | Genistein results in increased expression of MMP17 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 4313 |
MMP2
CLG4 CLG4A MMP-II MONA TBE-1 |
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) | Genistein results in decreased activity of MMP2 protein |
decreases activity
|
protein |
16598420
|
| D019833 | 4313 |
MMP2
CLG4 CLG4A MMP-II MONA TBE-1 |
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) | Genistein results in decreased expression of MMP2 mRNA |
decreases expression
|
mRNA |
15754008
|
| D019833 | 4318 |
MMP9
CLG4B GELB MANDP2 MMP-9 |
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) | Genistein results in decreased activity of MMP9 protein |
decreases activity
|
protein |
16598420
|
| D019833 | 4318 |
MMP9
CLG4B GELB MANDP2 MMP-9 |
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) | Genistein results in decreased expression of MMP9 mRNA |
decreases expression
|
mRNA |
15256057
15754008 |
| D019833 | 4318 |
MMP9
CLG4B GELB MANDP2 MMP-9 |
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) | Genistein results in decreased expression of MMP9 protein |
decreases expression
|
protein |
15256057
|
| D019833 | 4331 |
MNAT1
CAP35 MAT1 RNF66 TFB3 |
MNAT CDK-activating kinase assembly factor 1 | Genistein results in increased expression of MNAT1 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 4335 |
MNT
MAD6 MXD6 ROX bHLHd3 |
MAX network transcriptional repressor | Genistein results in increased expression of MNT mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 7841 |
MOGS
CDG2B CWH41 DER7 GCS1 |
mannosyl-oligosaccharide glucosidase (EC:3.2.1.106) | ESR1 promotes the reaction [Genistein results in decreased expression of MOGS protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 7841 |
MOGS
CDG2B CWH41 DER7 GCS1 |
mannosyl-oligosaccharide glucosidase (EC:3.2.1.106) | Genistein results in decreased expression of MOGS protein |
decreases expression
|
protein |
20884965
|
| D019833 | 10198 |
MPHOSPH9
MPP-9 MPP9 |
M-phase phosphoprotein 9 | Genistein results in increased expression of MPHOSPH9 mRNA |
increases expression
|
mRNA |
16474171
16705744 |
| D019833 | 84954 |
MPND
|
MPN domain containing | Genistein results in increased expression of MPND mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 55052 |
MRPL20
L20mt MRP-L20 |
mitochondrial ribosomal protein L20 | ESR1 promotes the reaction [Genistein results in increased expression of MRPL20 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 55052 |
MRPL20
L20mt MRP-L20 |
mitochondrial ribosomal protein L20 | Genistein results in increased expression of MRPL20 protein |
increases expression
|
protein |
20884965
|
| D019833 | 740 |
MRPL49
C11orf4 L49mt MRP-L49 NOF NOF1 |
mitochondrial ribosomal protein L49 | Genistein results in decreased expression of MRPL49 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 124540 |
MSI2
MSI2H |
musashi RNA-binding protein 2 | Genistein results in decreased expression of MSI2 mRNA |
decreases expression
|
mRNA |
18847459
|
| D019833 | 4477 |
MSMB
HPC13 IGBF MSP MSPB PN44 PRPS PSP PSP-94 PSP57 PSP94 |
microseminoprotein, beta- | Genistein results in increased expression of MSMB mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 4501 |
MT1X
MT-1l MT1 |
metallothionein 1X | Genistein results in increased expression of MT1X mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 4502 |
MT2A
MT2 |
metallothionein 2A | Genistein results in increased expression of MT2A mRNA |
increases expression
|
mRNA |
10656621
|
| D019833 | 4522 |
MTHFD1
MTHFC MTHFD |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (EC:1.5.1.5 6.3.4.3 3.5.4.9) | Genistein results in decreased expression of MTHFD1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 4582 |
MUC1
CA_15-3 CD227 EMA H23AG KL-6 MAM6 MCKD1 MUC-1 MUC-1/SEC MUC-1/X MUC1/ZD PEM PEMT PUM |
mucin 1, cell surface associated | ESR2 promotes the reaction [Genistein results in increased expression of MUC1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4582 |
MUC1
CA_15-3 CD227 EMA H23AG KL-6 MAM6 MCKD1 MUC-1 MUC-1/SEC MUC-1/X MUC1/ZD PEM PEMT PUM |
mucin 1, cell surface associated | Genistein results in increased expression of MUC1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 4597 |
MVD
FP17780 MPD |
mevalonate (diphospho) decarboxylase (EC:4.1.1.33) | Genistein results in decreased expression of MVD mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 4599 |
MX1
IFI-78K IFI78 MX MxA |
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | ESR2 promotes the reaction [Genistein results in decreased expression of MX1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4599 |
MX1
IFI-78K IFI78 MX MxA |
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | Genistein results in decreased expression of MX1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 10608 |
MXD4
MAD4 MST149 MSTP149 bHLHc12 |
MAX dimerization protein 4 | Genistein results in decreased expression of MXD4 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 439921 |
MXRA7
PS1TP1 TMAP1 |
matrix-remodelling associated 7 | Genistein results in increased expression of MXRA7 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 4602 |
MYB
Cmyb c-myb c-myb_CDS efg |
v-myb avian myeloblastosis viral oncogene homolog | Genistein results in increased expression of MYB mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 10514 |
MYBBP1A
P160 PAP2 |
MYB binding protein (P160) 1a | Genistein results in increased expression of MYBBP1A mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 4605 |
MYBL2
B-MYB BMYB |
v-myb avian myeloblastosis viral oncogene homolog-like 2 | Genistein results in increased expression of MYBL2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 4609 |
MYC
MRTL MYCC bHLHe39 c-Myc |
v-myc avian myelocytomatosis viral oncogene homolog | [Genistein co-treated with arsenic trioxide] results in decreased expression of MYC protein |
affects cotreatment
/ decreases expression |
protein |
21078540
|
| D019833 | 4609 |
MYC
MRTL MYCC bHLHe39 c-Myc |
v-myc avian myelocytomatosis viral oncogene homolog | Genistein results in decreased expression of MYC protein |
decreases expression
|
protein |
21078540
|
| D019833 | 4609 |
MYC
MRTL MYCC bHLHe39 c-Myc |
v-myc avian myelocytomatosis viral oncogene homolog | Genistein results in increased expression of MYC mRNA |
increases expression
|
mRNA |
16474171
17266178 23019147 |
| D019833 | 4628 |
MYH10
NMMHC-IIB NMMHCB |
myosin, heavy chain 10, non-muscle | ESR1 promotes the reaction [Genistein results in increased expression of MYH10 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4628 |
MYH10
NMMHC-IIB NMMHCB |
myosin, heavy chain 10, non-muscle | Genistein results in increased expression of MYH10 protein |
increases expression
|
protein |
20884965
|
| D019833 | 79784 |
MYH14
DFNA4 DFNA4A MHC16 MYH17 NMHC_II-C NMHC-II-C PNMHH myosin |
myosin, heavy chain 14, non-muscle (EC:3.6.4.1) | ESR1 promotes the reaction [Genistein results in increased expression of MYH14 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 79784 |
MYH14
DFNA4 DFNA4A MHC16 MYH17 NMHC_II-C NMHC-II-C PNMHH myosin |
myosin, heavy chain 14, non-muscle (EC:3.6.4.1) | Genistein results in increased expression of MYH14 protein |
increases expression
|
protein |
20884965
|
| D019833 | 4624 |
MYH6
ASD3 CMD1EE CMH14 MYHC MYHCA SSS3 alpha-MHC |
myosin, heavy chain 6, cardiac muscle, alpha | Genistein results in decreased expression of MYH6 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 4627 |
MYH9
BDPLT6 DFNA17 EPSTS FTNS MHA NMHC-II-A NMMHC-IIA NMMHCA |
myosin, heavy chain 9, non-muscle | ESR1 promotes the reaction [Genistein results in increased expression of MYH9 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4627 |
MYH9
BDPLT6 DFNA17 EPSTS FTNS MHA NMHC-II-A NMMHC-IIA NMMHCA |
myosin, heavy chain 9, non-muscle | Genistein results in increased expression of MYH9 protein |
increases expression
|
protein |
20884965
|
| D019833 | 103910 |
MYL12B
MLC-B MRLC2 |
myosin, light chain 12B, regulatory | ESR1 promotes the reaction [Genistein results in increased expression of MYL12B protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 103910 |
MYL12B
MLC-B MRLC2 |
myosin, light chain 12B, regulatory | Genistein results in increased expression of MYL12B protein |
increases expression
|
protein |
20884965
|
| D019833 | 4637 |
MYL6
ESMLC LC17 LC17-GI LC17-NM LC17A LC17B MLC-3 MLC1SM MLC3NM MLC3SM |
myosin, light chain 6, alkali, smooth muscle and non-muscle | ESR1 promotes the reaction [Genistein results in increased expression of MYL6 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4637 |
MYL6
ESMLC LC17 LC17-GI LC17-NM LC17A LC17B MLC-3 MLC1SM MLC3NM MLC3SM |
myosin, light chain 6, alkali, smooth muscle and non-muscle | Genistein results in increased expression of MYL6 protein |
increases expression
|
protein |
20884965
|
| D019833 | 29116 |
MYLIP
IDOL MIR |
myosin regulatory light chain interacting protein (EC:6.3.2.-) | Genistein results in increased expression of MYLIP mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 51168 |
MYO15A
DFNB3 MYO15 |
myosin XVA | ESR1 promotes the reaction [Genistein results in decreased expression of MYO15A protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 51168 |
MYO15A
DFNB3 MYO15 |
myosin XVA | Genistein results in decreased expression of MYO15A protein |
decreases expression
|
protein |
20884965
|
| D019833 | 399687 |
MYO18A
MYSPDZ SPR210 |
myosin XVIIIA | Genistein results in increased expression of MYO18A mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 27163 |
NAAA
ASAHL PLT |
N-acylethanolamine acid amidase (EC:3.5.1.-) | Genistein results in increased expression of NAAA mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 4665 |
NAB2
MADER |
NGFI-A binding protein 2 (EGR1 binding protein 2) | Genistein results in increased expression of NAB2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 4676 |
NAP1L4
NAP1L4b NAP2 NAP2L hNAP2 |
nucleosome assembly protein 1-like 4 | Genistein results in decreased expression of NAP1L4 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 8775 |
NAPA
SNAPA |
N-ethylmaleimide-sensitive factor attachment protein, alpha | Genistein results in decreased expression of NAPA mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 26502 |
NARF
IOP2 |
nuclear prelamin A recognition factor | Genistein results in increased expression of NARF mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 4678 |
NASP
FLB7527 PRO1999 |
nuclear autoantigenic sperm protein (histone-binding) | ESR1 promotes the reaction [Genistein results in decreased expression of NASP protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4678 |
NASP
FLB7527 PRO1999 |
nuclear autoantigenic sperm protein (histone-binding) | Genistein results in decreased expression of NASP protein |
decreases expression
|
protein |
20884965
|
| D019833 | 339983 |
NAT8L
CML3 NACED NAT8-LIKE |
N-acetyltransferase 8-like (GCN5-related, putative) (EC:2.3.1.17) | Genistein results in increased expression of NAT8L mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 4683 |
NBN
AT-V1 AT-V2 ATV NBS NBS1 P95 |
nibrin | ESR1 promotes the reaction [Genistein results in increased expression of NBN protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4683 |
NBN
AT-V1 AT-V2 ATV NBS NBS1 P95 |
nibrin | Genistein results in increased expression of NBN protein |
increases expression
|
protein |
20884965
|
| D019833 | 9918 |
NCAPD2
CAP-D2 CNAP1 hCAP-D2 |
non-SMC condensin I complex, subunit D2 | Genistein results in increased expression of NCAPD2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 64151 |
NCAPG
CAPG CHCG NY-MEL-3 |
non-SMC condensin I complex, subunit G | Genistein affects the expression of NCAPG mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 64151 |
NCAPG
CAPG CHCG NY-MEL-3 |
non-SMC condensin I complex, subunit G | Genistein results in increased expression of NCAPG mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 400746 |
NCMAP
C1orf130 MP11 |
noncompact myelin associated protein | Genistein results in increased expression of NCMAP mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 8648 |
NCOA1
F-SRC-1 KAT13A RIP160 SRC1 bHLHe42 bHLHe74 |
nuclear receptor coactivator 1 (EC:2.3.1.48) | Genistein promotes the reaction [ESR1 protein binds to NCOA1 protein] |
affects binding
/ increases reaction |
protein |
10964929
|
| D019833 | 8648 |
NCOA1
F-SRC-1 KAT13A RIP160 SRC1 bHLHe42 bHLHe74 |
nuclear receptor coactivator 1 (EC:2.3.1.48) | Genistein promotes the reaction [ESR2 protein binds to NCOA1 protein] |
affects binding
/ increases reaction |
protein |
10964929
|
| D019833 | 10499 |
NCOA2
GRIP1 KAT13C NCoA-2 SRC2 TIF2 bHLHe75 |
nuclear receptor coactivator 2 | [Genistein binds to ESR1 protein] which binds to NCOA2 protein |
affects binding
|
protein |
15123288
|
| D019833 | 10499 |
NCOA2
GRIP1 KAT13C NCoA-2 SRC2 TIF2 bHLHe75 |
nuclear receptor coactivator 2 | [Genistein binds to ESR2 protein] which binds to NCOA2 protein |
affects binding
|
protein |
15123288
|
| D019833 | 10499 |
NCOA2
GRIP1 KAT13C NCoA-2 SRC2 TIF2 bHLHe75 |
nuclear receptor coactivator 2 | Genistein promotes the reaction [ESR1 protein binds to NCOA2 protein] |
affects binding
/ increases reaction |
protein |
10964929
|
| D019833 | 10499 |
NCOA2
GRIP1 KAT13C NCoA-2 SRC2 TIF2 bHLHe75 |
nuclear receptor coactivator 2 | Genistein promotes the reaction [ESR2 protein binds to NCOA2 protein] |
affects binding
/ increases reaction |
protein |
10964929
|
| D019833 | 10499 |
NCOA2
GRIP1 KAT13C NCoA-2 SRC2 TIF2 bHLHe75 |
nuclear receptor coactivator 2 | Genistein promotes the reaction [NCOA2 protein binds to ESR1 protein] |
affects binding
/ increases reaction |
protein |
15084758
|
| D019833 | 8202 |
NCOA3
ACTR AIB-1 AIB1 CAGH16 CTG26 KAT13B RAC3 SRC-3 SRC3 TNRC14 TNRC16 TRAM-1 bHLHe42 pCIP |
nuclear receptor coactivator 3 (EC:2.3.1.48) | Genistein results in decreased expression of NCOA3 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 8031 |
NCOA4
ARA70 ELE1 PTC3 RFG |
nuclear receptor coactivator 4 | Genistein results in increased expression of NCOA4 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 10403 |
NDC80
HEC HEC1 HsHec1 KNTC2 TID3 hsNDC80 |
NDC80 kinetochore complex component | Genistein results in increased expression of NDC80 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 4707 |
NDUFB1
CI-MNLL CI-SGDH MNLL |
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | Genistein results in decreased expression of NDUFB1 mRNA |
decreases expression
|
mRNA |
18847459
|
| D019833 | 4739 |
NEDD9
CAS-L CAS2 CASL CASS2 HEF1 |
neural precursor cell expressed, developmentally down-regulated 9 | Genistein results in decreased expression of NEDD9 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 252969 |
NEIL2
NEH2 NEI2 |
nei endonuclease VIII-like 2 (E. coli) (EC:4.2.99.18) | Genistein results in increased expression of NEIL2 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 4753 |
NELL2
NRP2 |
NEL-like 2 (chicken) | Genistein results in decreased expression of NELL2 mRNA |
decreases expression
|
mRNA |
15257099
|
| D019833 | 10725 |
NFAT5
NF-AT5 NFATL1 NFATZ OREBP TONEBP |
nuclear factor of activated T-cells 5, tonicity-responsive | ESR1 promotes the reaction [Genistein results in increased expression of NFAT5 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 10725 |
NFAT5
NF-AT5 NFATL1 NFATZ OREBP TONEBP |
nuclear factor of activated T-cells 5, tonicity-responsive | Genistein results in increased expression of NFAT5 protein |
increases expression
|
protein |
20884965
|
| D019833 | 4790 |
NFKB1
EBP-1 KBF1 NF-kB1 NF-kappa-B NF-kappaB NFKB-p105 NFKB-p50 NFkappaB p105 p50 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | Genistein affects the localization of NFKB1 protein |
affects localization
|
protein |
18431742
|
| D019833 | 4791 |
NFKB2
H2TF1 LYT-10 LYT10 NF-kB2 p105 p52 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | ESR2 promotes the reaction [Genistein results in decreased expression of NFKB2 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4791 |
NFKB2
H2TF1 LYT-10 LYT10 NF-kB2 p105 p52 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | Genistein results in decreased expression of NFKB2 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 4792 |
NFKBIA
IKBA MAD-3 NFKBI |
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | Genistein affects the localization of NFKBIA protein |
affects localization
|
protein |
18431742
|
| D019833 | 4792 |
NFKBIA
IKBA MAD-3 NFKBI |
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | Genistein results in decreased expression of NFKBIA mRNA |
decreases expression
|
mRNA |
20816778
|
| D019833 | 9054 |
NFS1
IscS NIFS |
NFS1 cysteine desulfurase (EC:2.8.1.7) | ESR1 promotes the reaction [Genistein results in decreased expression of NFS1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 9054 |
NFS1
IscS NIFS |
NFS1 cysteine desulfurase (EC:2.8.1.7) | Genistein results in decreased expression of NFS1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 374354 |
NHLRC2
|
NHL repeat containing 2 | Genistein results in decreased expression of NHLRC2 mRNA |
decreases expression
|
mRNA |
18847459
|
| D019833 | 4814 |
NINJ1
NIN1 NINJURIN |
ninjurin 1 | Genistein results in increased expression of NINJ1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 348938 |
NIPAL4
ARCI6 ICHTHYIN ICHYN |
NIPA-like domain containing 4 | Genistein results in decreased expression of NIPAL4 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 25836 |
NIPBL
CDLS CDLS1 IDN3 IDN3-B Scc2 |
Nipped-B homolog (Drosophila) | Genistein results in increased expression of NIPBL mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 4824 |
NKX3-1
BAPX2 NKX3 NKX3.1 NKX3A |
NK3 homeobox 1 | Genistein results in decreased expression of NKX3-1 mRNA |
decreases expression
|
mRNA |
15378649
16865672 |
| D019833 | 57486 |
NLN
AGTBP EP24.16 MEP MOP |
neurolysin (metallopeptidase M3 family) (EC:3.4.24.16) | ESR1 promotes the reaction [Genistein results in decreased expression of NLN protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 57486 |
NLN
AGTBP EP24.16 MEP MOP |
neurolysin (metallopeptidase M3 family) (EC:3.4.24.16) | Genistein results in decreased expression of NLN protein |
decreases expression
|
protein |
20884965
|
| D019833 | 4836 |
NMT1
NMT |
N-myristoyltransferase 1 (EC:2.3.1.97) | Genistein results in decreased expression of NMT1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 65083 |
NOL6
NRAP UTP22 bA311H10.1 |
nucleolar protein 6 (RNA-associated) | Genistein results in increased expression of NOL6 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 4839 |
NOP2
NOL1 NOP120 NSUN1 p120 |
NOP2 nucleolar protein | Genistein results in increased expression of NOP2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 4843 |
NOS2
HEP-NOS INOS NOS NOS2A |
nitric oxide synthase 2, inducible (EC:1.14.13.39) | Genistein results in decreased expression of NOS2 mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 404036 | Genistein results in decreased expression of NOS2A mRNA |
decreases expression
|
mRNA |
20816778
|
||
| D019833 | 4846 |
NOS3
ECNOS eNOS |
nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) | Genistein inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS3 mRNA] |
decreases reaction
/ increases expression |
mRNA |
20021702
|
| D019833 | 4846 |
NOS3
ECNOS eNOS |
nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) | Genistein results in decreased expression of NOS3 mRNA |
decreases expression
|
mRNA |
20021702
|
| D019833 | 4846 |
NOS3
ECNOS eNOS |
nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) | Genistein results in increased activity of NOS3 protein |
increases activity
|
protein |
16840783
|
| D019833 | 4846 |
NOS3
ECNOS eNOS |
nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) | Genistein results in increased expression of NOS3 mRNA |
increases expression
|
mRNA |
20706672
|
| D019833 | 10577 |
NPC2
EDDM1 HE1 |
Niemann-Pick disease, type C2 | ESR1 promotes the reaction [Genistein results in decreased expression of NPC2 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 10577 |
NPC2
EDDM1 HE1 |
Niemann-Pick disease, type C2 | Genistein results in decreased expression of NPC2 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 9284 |
NPIPA1
NPIP morpheus |
nuclear pore complex interacting protein family, member A1 | Genistein results in decreased expression of NPIPA1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 23117 |
NPIPB3
KIAA0220L NPIPB5 NPIPL3 |
nuclear pore complex interacting protein family, member B3 | Genistein results in increased expression of NPIPB3 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 4869 |
NPM1
B23 NPM |
nucleophosmin (nucleolar phosphoprotein B23, numatrin) | ESR1 promotes the reaction [Genistein results in increased expression of NPM1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4869 |
NPM1
B23 NPM |
nucleophosmin (nucleolar phosphoprotein B23, numatrin) | ESR2 promotes the reaction [Genistein results in increased expression of NPM1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4869 |
NPM1
B23 NPM |
nucleophosmin (nucleolar phosphoprotein B23, numatrin) | Genistein results in increased expression of NPM1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 4880 |
NPPC
CNP CNP2 |
natriuretic peptide C | Genistein results in increased expression of NPPC mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 4881 |
NPR1
ANPRA ANPa GUC2A GUCY2A NPRA |
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) (EC:4.6.1.2) | Genistein results in increased expression of NPR1 mRNA |
increases expression
|
mRNA |
16399490
|
| D019833 | 283869 |
NPW
L8 L8C PPL8 PPNPW |
neuropeptide W | Genistein results in increased expression of NPW mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 1728 |
NQO1
DHQU DIA4 DTD NMOR1 NMORI QR1 |
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) | Genistein results in decreased expression of NQO1 mRNA |
decreases expression
|
mRNA |
18497090
|
| D019833 | 1728 |
NQO1
DHQU DIA4 DTD NMOR1 NMORI QR1 |
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) | Genistein results in increased expression of NQO1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 8856 |
NR1I2
BXR ONR1 PAR PAR1 PAR2 PARq PRR PXR SAR SXR |
nuclear receptor subfamily 1, group I, member 2 | Genistein binds to and results in increased activity of NR1I2 protein |
affects binding
/ increases activity |
protein |
16054614
|
| D019833 | 7182 |
NR2C2
TAK1 TR2R1 TR4 hTAK1 |
nuclear receptor subfamily 2, group C, member 2 | Genistein results in decreased expression of NR2C2 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 3164 |
NR4A1
GFRP1 HMR N10 NAK-1 NGFIB NP10 NUR77 TR3 |
nuclear receptor subfamily 4, group A, member 1 | Genistein results in decreased expression of NR4A1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 3164 |
NR4A1
GFRP1 HMR N10 NAK-1 NGFIB NP10 NUR77 TR3 |
nuclear receptor subfamily 4, group A, member 1 | Genistein results in increased expression of NR4A1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 441478 |
NRARP
|
NOTCH-regulated ankyrin repeat protein | Genistein results in decreased expression of NRARP mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 29959 |
NRBP1
BCON3 MADM MUDPNP NRBP |
nuclear receptor binding protein 1 | Genistein results in decreased expression of NRBP1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 8204 |
NRIP1
RIP140 |
nuclear receptor interacting protein 1 | Genistein results in increased expression of NRIP1 mRNA |
increases expression
|
mRNA |
15757668
19371625 23019147 |
| D019833 | 56675 |
NRIP3
C11orf14 NY-SAR-105 |
nuclear receptor interacting protein 3 | Genistein results in increased expression of NRIP3 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 8829 |
NRP1
BDCA4 CD304 NP1 NRP VEGF165R |
neuropilin 1 | Genistein affects the expression of NRP1 mRNA |
affects expression
|
mRNA |
16399490
|
| D019833 | 8828 |
NRP2
NP2 NPN2 PRO2714 VEGF165R2 |
neuropilin 2 | Genistein affects the expression of NRP2 mRNA |
affects expression
|
mRNA |
16399490
|
| D019833 | 4902 |
NRTN
NTN |
neurturin | Genistein results in increased expression of NRTN mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 4926 |
NUMA1
NUMA |
nuclear mitotic apparatus protein 1 | ESR2 promotes the reaction [Genistein results in increased expression of NUMA1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 4926 |
NUMA1
NUMA |
nuclear mitotic apparatus protein 1 | Genistein results in increased expression of NUMA1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 158046 |
NXNL2
C9orf121 RDCVF2 |
nucleoredoxin-like 2 (EC:1.8.1.8) | Genistein results in increased expression of NXNL2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 100506658 |
OCLN
BLCPMG |
occludin (EC:2.1.1.67) | Genistein results in decreased expression of OCLN mRNA |
decreases expression
|
mRNA |
20816778
|
| D019833 | 11054 |
OGFR
|
opioid growth factor receptor | Genistein results in increased expression of OGFR mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 10439 |
OLFM1
AMY NOE1 NOELIN1 OlfA |
olfactomedin 1 | Genistein results in increased expression of OLFM1 mRNA |
increases expression
|
mRNA |
16474171
19371625 |
| D019833 | 56944 |
OLFML3
HNOEL-iso OLF44 |
olfactomedin-like 3 | [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of OLFML3 mRNA |
affects cotreatment
/ increases expression |
mRNA |
16963248
|
| D019833 | 56944 |
OLFML3
HNOEL-iso OLF44 |
olfactomedin-like 3 | Genistein results in increased expression of OLFML3 mRNA |
increases expression
|
mRNA |
16474171
19371625 23019147 |
| D019833 | 29948 |
OSGIN1
BDGI OKL38 |
oxidative stress induced growth inhibitor 1 | Genistein results in increased expression of OSGIN1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 78990 |
OTUB2
C14orf137 OTB2 OTU2 |
OTU domain, ubiquitin aldehyde binding 2 (EC:3.4.19.12) | Genistein results in increased expression of OTUB2 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 5032 |
P2RY11
P2Y11 |
purinergic receptor P2Y, G-protein coupled, 11 | Genistein results in increased expression of P2RY11 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 5036 |
PA2G4
EBP1 HG4-1 p38-2G4 |
proliferation-associated 2G4, 38kDa | Genistein results in decreased expression of PA2G4 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 5064 |
PALM
|
paralemmin | Genistein results in increased expression of PALM mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 142 |
PARP1
ADPRT ADPRT_1 ADPRT1 ARTD1 PARP PARP-1 PPOL pADPRT-1 |
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) | [Fluorouracil co-treated with Genistein] results in increased cleavage of PARP1 protein |
affects cotreatment
/ increases cleavage |
protein |
15896711
|
| D019833 | 142 |
PARP1
ADPRT ADPRT_1 ADPRT1 ARTD1 PARP PARP-1 PPOL pADPRT-1 |
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) | [Genistein co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein |
affects cotreatment
/ increases cleavage |
protein |
21078540
|
| D019833 | 142 |
PARP1
ADPRT ADPRT_1 ADPRT1 ARTD1 PARP PARP-1 PPOL pADPRT-1 |
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) | Genistein results in increased cleavage of PARP1 protein |
increases cleavage
|
protein |
12791511
21078540 |
| D019833 | 55872 |
PBK
CT84 Nori-3 SPK TOPK |
PDZ binding kinase (EC:2.7.12.2) | Genistein affects the expression of PBK mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 55872 |
PBK
CT84 Nori-3 SPK TOPK |
PDZ binding kinase (EC:2.7.12.2) | Genistein results in increased expression of PBK mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 56133 |
PCDHB2
PCDH-BETA2 |
protocadherin beta 2 | Genistein results in increased expression of PCDHB2 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 56130 |
PCDHB6
PCDH-BETA6 |
protocadherin beta 6 | Genistein results in increased expression of PCDHB6 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 5106 |
PCK2
PEPCK PEPCK-M PEPCK2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) (EC:4.1.1.32) | Genistein results in increased expression of PCK2 mRNA |
increases expression
|
mRNA |
15757668
|
| D019833 | 5111 |
PCNA
|
proliferating cell nuclear antigen | Genistein results in decreased expression of PCNA |
decreases expression
|
21161820
|
|
| D019833 | 5111 |
PCNA
|
proliferating cell nuclear antigen | Genistein results in decreased expression of PCNA protein |
decreases expression
|
protein |
16149052
|
| D019833 | 5111 |
PCNA
|
proliferating cell nuclear antigen | Genistein results in increased expression of PCNA mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 5121 |
PCP4
PEP-19 |
Purkinje cell protein 4 | Genistein results in increased expression of PCP4 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 22984 |
PDCD11
ALG-4 ALG4 NFBP RRP5 |
programmed cell death 11 | Genistein results in increased expression of PDCD11 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 27250 |
PDCD4
H731 |
programmed cell death 4 (neoplastic transformation inhibitor) | Genistein results in increased expression of PDCD4 mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 10015 |
PDCD6IP
AIP1 ALIX DRIP4 HP95 |
programmed cell death 6 interacting protein | Genistein results in increased expression of PDCD6IP mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 10081 |
PDCD7
ES18 HES18 |
programmed cell death 7 | Genistein results in increased expression of PDCD7 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 100135774 | Genistein inhibits the reaction [Chondroitin Sulfates promotes the reaction [PDGF protein results in increased phosphorylation of and results in increased activity of PDGFRB protein]] |
decreases reaction
/ increases activity / increases phosphorylation / increases reaction |
protein |
16945567
|
||
| D019833 | 5159 |
PDGFRB
CD140B IBGC4 IMF1 JTK12 PDGFR PDGFR-1 PDGFR1 |
platelet-derived growth factor receptor, beta polypeptide (EC:2.7.10.1) | Genistein inhibits the reaction [Chondroitin Sulfates promotes the reaction [PDGF protein results in increased phosphorylation of and results in increased activity of PDGFRB protein]] |
decreases reaction
/ increases activity / increases phosphorylation / increases reaction |
protein |
16945567
|
| D019833 | 10954 |
PDIA5
PDIR |
protein disulfide isomerase family A, member 5 (EC:5.3.4.1) | Genistein results in increased expression of PDIA5 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 5163 |
PDK1
|
pyruvate dehydrogenase kinase, isozyme 1 (EC:2.7.11.2) | Genistein results in decreased phosphorylation of PDK1 protein |
decreases phosphorylation
|
protein |
18431742
|
| D019833 | 64236 |
PDLIM2
MYSTIQUE SLIM |
PDZ and LIM domain 2 (mystique) | [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of PDLIM2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
16963248
|
| D019833 | 5174 |
PDZK1
CAP70 CLAMP NHERF-3 NHERF3 PDZD1 |
PDZ domain containing 1 | Genistein results in increased expression of PDZK1 mRNA |
increases expression
|
mRNA |
15757668
|
| D019833 | 23089 |
PEG10
EDR HB-1 MEF3L Mar2 Mart2 RGAG3 |
paternally expressed 10 | Genistein results in increased expression of PEG10 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 192111 |
PGAM5
BXLBV68 |
phosphoglycerate mutase family member 5 (EC:3.1.3.16) | Genistein results in increased expression of PGAM5 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 54858 |
PGPEP1
PGP PGP-I PGPI Pcp |
pyroglutamyl-peptidase I (EC:3.4.19.3) | Genistein results in increased expression of PGPEP1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 5241 |
PGR
NR3C3 PR |
progesterone receptor | ESR1 protein inhibits the reaction [Genistein results in increased expression of PGR mRNA] |
decreases reaction
/ increases expression |
mRNA |
23384675
|
| D019833 | 5241 |
PGR
NR3C3 PR |
progesterone receptor | Genistein results in decreased expression of PGR mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 5241 |
PGR
NR3C3 PR |
progesterone receptor | Genistein results in increased expression of PGR mRNA |
increases expression
|
mRNA |
11368622
16076101 19371625 20884965 23384675 23524099 |
| D019833 | 9678 |
PHF14
|
PHD finger protein 14 | Genistein results in decreased expression of PHF14 mRNA |
decreases expression
|
mRNA |
15256057
|
| D019833 | 7262 |
PHLDA2
BRW1C BWR1C HLDA2 IPL TSSC3 |
pleckstrin homology-like domain, family A, member 2 | Genistein results in increased expression of PHLDA2 mRNA |
increases expression
|
mRNA |
15256057
23019147 |
| D019833 | 5296 |
PIK3R2
MPPH P85B p85 p85-BETA |
phosphoinositide-3-kinase, regulatory subunit 2 (beta) | Genistein results in decreased expression of PIK3R2 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 8503 |
PIK3R3
p55 p55-GAMMA |
phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | Genistein results in increased expression of PIK3R3 mRNA |
increases expression
|
mRNA |
15378649
|
| D019833 | 29990 |
PILRB
FDFACT1 FDFACT2 |
paired immunoglobin-like type 2 receptor beta | Genistein results in decreased expression of PILRB mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 5292 |
PIM1
PIM |
pim-1 oncogene (EC:2.7.11.1) | Genistein results in increased expression of PIM1 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 5304 |
PIP
GCDFP-15 GCDFP15 GPIP4 |
prolactin-induced protein | ESR1 promotes the reaction [Genistein results in decreased expression of PIP protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 5304 |
PIP
GCDFP-15 GCDFP15 GPIP4 |
prolactin-induced protein | ESR2 promotes the reaction [Genistein results in increased expression of PIP protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 5304 |
PIP
GCDFP-15 GCDFP15 GPIP4 |
prolactin-induced protein | Genistein results in decreased expression of PIP protein |
decreases expression
|
protein |
20884965
|
| D019833 | 5304 |
PIP
GCDFP-15 GCDFP15 GPIP4 |
prolactin-induced protein | Genistein results in increased expression of PIP protein |
increases expression
|
protein |
20884965
|
| D019833 | 51268 |
PIPOX
LPIPOX |
pipecolic acid oxidase (EC:1.5.3.1 1.5.3.7) | Genistein results in increased expression of PIPOX mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 26207 |
PITPNC1
M-RDGB-beta MRDGBbeta RDGB-BETA RDGBB RDGBB1 |
phosphatidylinositol transfer protein, cytoplasmic 1 | Genistein results in increased expression of PITPNC1 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 5320 |
PLA2G2A
MOM1 PLA2 PLA2B PLA2L PLA2S PLAS1 sPLA2 |
phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4) | Genistein results in decreased expression of PLA2G2A mRNA |
decreases expression
|
mRNA |
20816778
|
| D019833 | 5327 |
PLAT
T-PA TPA |
plasminogen activator, tissue (EC:3.4.21.68) | Genistein results in increased expression of PLAT mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 5328 |
PLAU
ATF BDPLT5 QPD UPA URK u-PA |
plasminogen activator, urokinase (EC:3.4.21.73) | Genistein results in decreased expression of PLAU mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 5328 |
PLAU
ATF BDPLT5 QPD UPA URK u-PA |
plasminogen activator, urokinase (EC:3.4.21.73) | Genistein results in increased expression of PLAU mRNA |
increases expression
|
mRNA |
18025290
|
| D019833 | 23236 |
PLCB1
EIEE12 PI-PLC PLC-154 PLC-I PLC154 PLCB1A PLCB1B |
phospholipase C, beta 1 (phosphoinositide-specific) (EC:3.1.4.11) | Genistein results in increased expression of PLCB1 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 5339 |
PLEC
EBS1 EBSO HD1 LGMD2Q PCN PLEC1 PLEC1b PLTN |
plectin | Genistein results in decreased expression of PLEC mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 10769 |
PLK2
SNK hPlk2 hSNK |
polo-like kinase 2 (EC:2.7.11.21) | Genistein results in decreased expression of PLK2 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 10733 |
PLK4
SAK STK18 |
polo-like kinase 4 (EC:2.7.11.21) | Genistein results in increased expression of PLK4 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 5351 |
PLOD1
EDS6 LH LH1 LLH PLOD |
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (EC:1.14.11.4) | Genistein results in increased expression of PLOD1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 8985 |
PLOD3
LH3 |
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (EC:1.14.11.4) | Genistein results in increased expression of PLOD3 mRNA |
increases expression
|
mRNA |
20706672
|
| D019833 | 5354 |
PLP1
GPM6C HLD1 MMPL PLP PLP/DM20 PMD SPG2 |
proteolipid protein 1 | Genistein results in decreased expression of PLP1 mRNA |
decreases expression
|
mRNA |
18444173
|
| D019833 | 5364 |
PLXNB1
PLEXIN-B1 PLXN5 SEP |
plexin B1 | Genistein results in decreased expression of PLXNB1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 56937 |
PMEPA1
STAG1 TMEPAI |
prostate transmembrane protein, androgen induced 1 | Genistein results in decreased expression of PMEPA1 mRNA |
decreases expression
|
mRNA |
15378649
16474171 |
| D019833 | 25953 |
PNKD
BRP17 DYT8 FPD1 KIPP1184 MR-1 MR1 PDC PKND1 TAHCCP2 |
paroxysmal nonkinesigenic dyskinesia (EC:3.1.2.6) | ESR1 promotes the reaction [Genistein results in decreased expression of PNKD protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 25953 |
PNKD
BRP17 DYT8 FPD1 KIPP1184 MR-1 MR1 PDC PKND1 TAHCCP2 |
paroxysmal nonkinesigenic dyskinesia (EC:3.1.2.6) | Genistein results in decreased expression of PNKD protein |
decreases expression
|
protein |
20884965
|
| D019833 | 5411 |
PNN
DRS DRSP SDK3 memA |
pinin, desmosome associated protein | [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of PNN mRNA |
affects cotreatment
/ increases expression |
mRNA |
16963248
|
| D019833 | 10957 |
PNRC1
B4-2 PNAS-145 PROL2 PRR2 |
proline-rich nuclear receptor coactivator 1 | Genistein promotes the reaction [ESRRB protein binds to PNRC1 protein] |
affects binding
/ increases reaction |
protein |
14638870
|
| D019833 | 10957 |
PNRC1
B4-2 PNAS-145 PROL2 PRR2 |
proline-rich nuclear receptor coactivator 1 | Genistein promotes the reaction [ESRRG protein binds to PNRC1 protein] |
affects binding
/ increases reaction |
protein |
14638870
|
| D019833 | 10957 |
PNRC1
B4-2 PNAS-145 PROL2 PRR2 |
proline-rich nuclear receptor coactivator 1 | Genistein results in decreased expression of PNRC1 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 23509 |
POFUT1
DDD2 FUT12 O-FUT O-Fuc-T O-FucT-1 OFUCT1 |
protein O-fucosyltransferase 1 (EC:2.4.1.221) | ESR1 promotes the reaction [Genistein results in decreased expression of POFUT1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 23509 |
POFUT1
DDD2 FUT12 O-FUT O-Fuc-T O-FucT-1 OFUCT1 |
protein O-fucosyltransferase 1 (EC:2.4.1.221) | Genistein results in decreased expression of POFUT1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 57804 |
POLD4
POLDS p12 |
polymerase (DNA-directed), delta 4, accessory subunit | Genistein results in decreased expression of POLD4 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 5432 |
POLR2C
RPB3 RPB31 hRPB33 hsRPB3 |
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa (EC:2.7.7.6) | Genistein results in increased expression of POLR2C mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 5442 |
POLRMT
APOLMT MTRNAP MTRPOL h-mtRPOL |
polymerase (RNA) mitochondrial (DNA directed) (EC:2.7.7.6) | Genistein results in increased expression of POLRMT mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 5443 |
POMC
ACTH CLIP LPH MSH NPP POC |
proopiomelanocortin | Genistein results in decreased expression of POMC mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 5458 |
POU4F2
BRN3.2 BRN3B Brn-3b |
POU class 4 homeobox 2 | [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of POU4F2 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
16963248
|
| D019833 | 56342 |
PPAN
BXDC3 SSF SSF-1 SSF1 SSF2 |
peter pan homolog (Drosophila) | Genistein results in increased expression of PPAN mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 8613 |
PPAP2B
Dri42 LPP3 PAP2B VCIP |
phosphatidic acid phosphatase type 2B (EC:3.1.3.4) | Genistein results in decreased expression of PPAP2B mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 8613 |
PPAP2B
Dri42 LPP3 PAP2B VCIP |
phosphatidic acid phosphatase type 2B (EC:3.1.3.4) | Genistein results in increased expression of PPAP2B mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 8612 |
PPAP2C
LPP2 PAP-2c PAP2-g |
phosphatidic acid phosphatase type 2C (EC:3.1.3.4) | Genistein results in decreased expression of PPAP2C mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 5468 |
PPARG
CIMT1 GLM1 NR1C3 PPARG1 PPARG2 PPARgamma |
peroxisome proliferator-activated receptor gamma | Genistein results in decreased expression of PPARG mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 133522 |
PPARGC1B
ERRL1 PERC PGC-1(beta) PGC1B |
peroxisome proliferator-activated receptor gamma, coactivator 1 beta | Genistein results in increased expression of PPARGC1B mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 8496 |
PPFIBP1
L2 SGT2 hSGT2 hSgt2p |
PTPRF interacting protein, binding protein 1 (liprin beta 1) | Genistein results in decreased expression of PPFIBP1 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 5493 |
PPL
|
periplakin | ESR2 promotes the reaction [Genistein results in decreased expression of PPL protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 5493 |
PPL
|
periplakin | Genistein results in decreased expression of PPL protein |
decreases expression
|
protein |
20884965
|
| D019833 | 333926 |
PPM1J
PP2CZ PP2Czeta PPP2CZ |
protein phosphatase, Mg2+/Mn2+ dependent, 1J (EC:3.1.3.16) | Genistein results in increased expression of PPM1J mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 5514 |
PPP1R10
CAT53 FB19 PNUTS PP1R10 R111 p99 |
protein phosphatase 1, regulatory subunit 10 | Genistein results in increased expression of PPP1R10 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 81706 |
PPP1R14C
CPI17-like KEPI NY-BR-81 |
protein phosphatase 1, regulatory (inhibitor) subunit 14C | Genistein results in increased expression of PPP1R14C mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 84152 |
PPP1R1B
DARPP-32 DARPP32 |
protein phosphatase 1, regulatory (inhibitor) subunit 1B (EC:3.1.3.16) | Genistein results in increased expression of PPP1R1B mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 5521 |
PPP2R2B
B55BETA PP2AB55BETA PP2ABBETA PP2APR55B PP2APR55BETA PR2AB55BETA PR2ABBETA PR2APR55BETA PR52B PR55-BETA PR55BETA SCA12 |
protein phosphatase 2, regulatory subunit B, beta (EC:3.1.3.16) | Genistein results in increased expression of PPP2R2B mRNA |
increases expression
|
mRNA |
18444173
|
| D019833 | 5522 |
PPP2R2C
B55-GAMMA IMYPNO IMYPNO1 PR52 PR55G |
protein phosphatase 2, regulatory subunit B, gamma (EC:3.1.3.16) | Genistein results in increased expression of PPP2R2C mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 11230 |
PRAF2
|
PRA1 domain family, member 2 | ESR2 promotes the reaction [Genistein results in decreased expression of PRAF2 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 11230 |
PRAF2
|
PRA1 domain family, member 2 | Genistein results in decreased expression of PRAF2 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 9055 |
PRC1
ASE1 |
protein regulator of cytokinesis 1 | Genistein results in increased expression of PRC1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 5546 |
PRCC
RCCP1 TPRC |
papillary renal cell carcinoma (translocation-associated) | Genistein results in decreased expression of PRCC mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 57580 |
PREX1
P-REX1 |
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | ESR2 promotes the reaction [Genistein results in decreased expression of PREX1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 57580 |
PREX1
P-REX1 |
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | Genistein results in decreased expression of PREX1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 5557 |
PRIM1
p49 |
primase, DNA, polypeptide 1 (49kDa) (EC:2.7.7.7) | Genistein results in increased expression of PRIM1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 5562 |
PRKAA1
AMPK AMPKa1 |
protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31) | [Genistein co-treated with Capsaicin] results in increased activity of PRKAA1 protein |
affects cotreatment
/ increases activity |
protein |
19723084
|
| D019833 | 5576 |
PRKAR2A
PKR2 PRKAR2 |
protein kinase, cAMP-dependent, regulatory, type II, alpha (EC:2.7.11.1) | Genistein results in increased expression of PRKAR2A mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 5578 |
PRKCA
AAG6 PKC-alpha PKCA PRKACA |
protein kinase C, alpha (EC:2.7.11.13) | Genistein results in increased expression of PRKCA mRNA |
increases expression
|
mRNA |
16705744
|
| D019833 | 5580 |
PRKCD
MAY1 PKCD nPKC-delta |
protein kinase C, delta (EC:2.7.10.2 2.7.11.13) | Genistein results in decreased expression of PRKCD mRNA |
decreases expression
|
mRNA |
15757668
|
| D019833 | 3276 |
PRMT1
ANM1 HCP1 HRMT1L2 IR1B4 |
protein arginine methyltransferase 1 (EC:2.1.1.125) | ESR2 promotes the reaction [Genistein results in increased expression of PRMT1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 3276 |
PRMT1
ANM1 HCP1 HRMT1L2 IR1B4 |
protein arginine methyltransferase 1 (EC:2.1.1.125) | Genistein results in increased expression of PRMT1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 5621 |
PRNP
ASCR AltPrP CD230 CJD GSS KURU PRIP PrP PrP27-30 PrP33-35C PrPc p27-30 |
prion protein | Genistein results in increased expression of PRNP mRNA |
increases expression
|
mRNA |
18444173
|
| D019833 | 5627 |
PROS1
PROS PS21 PS22 PS23 PS24 PS25 PSA THPH5 THPH6 |
protein S (alpha) | Genistein results in decreased expression of PROS1 mRNA |
decreases expression
|
mRNA |
20926118
|
| D019833 | 10594 |
PRPF8
HPRP8 PRP8 PRPC8 RP13 SNRNP220 |
pre-mRNA processing factor 8 | Genistein results in decreased expression of PRPF8 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 5644 |
PRSS1
TRP1 TRY1 TRY4 TRYP1 |
protease, serine, 1 (trypsin 1) (EC:3.4.21.4) | Genistein results in decreased expression of PRSS1 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 11098 |
PRSS23
SIG13 SPUVE ZSIG13 |
protease, serine, 23 | ESR1 protein inhibits the reaction [Genistein results in increased expression of PRSS23 mRNA] |
decreases reaction
/ increases expression |
mRNA |
23384675
|
| D019833 | 11098 |
PRSS23
SIG13 SPUVE ZSIG13 |
protease, serine, 23 | Genistein results in increased expression of PRSS23 mRNA |
increases expression
|
mRNA |
23384675
|
| D019833 | 5652 |
PRSS8
CAP1 PROSTASIN |
protease, serine, 8 | ESR2 promotes the reaction [Genistein results in decreased expression of PRSS8 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 5652 |
PRSS8
CAP1 PROSTASIN |
protease, serine, 8 | Genistein results in decreased expression of PRSS8 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 29968 |
PSAT1
EPIP PSA PSAT |
phosphoserine aminotransferase 1 (EC:2.6.1.52) | Genistein results in increased expression of PSAT1 mRNA |
increases expression
|
mRNA |
15757668
|
| D019833 | 5728 |
PTEN
10q23del BZS CWS1 DEC GLM2 MHAM MMAC1 PTEN1 TEP1 |
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) | Genistein affects the expression of PTEN mRNA |
affects expression
|
mRNA |
18431742
|
| D019833 | 5728 |
PTEN
10q23del BZS CWS1 DEC GLM2 MHAM MMAC1 PTEN1 TEP1 |
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) | Genistein affects the expression of PTEN protein |
affects expression
|
protein |
18431742
|
| D019833 | 5728 |
PTEN
10q23del BZS CWS1 DEC GLM2 MHAM MMAC1 PTEN1 TEP1 |
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) | Genistein inhibits the reaction [HIST3H3 protein modified form binds to PTEN promoter] |
affects binding
/ decreases reaction |
promoter |
18431742
|
| D019833 | 5728 |
PTEN
10q23del BZS CWS1 DEC GLM2 MHAM MMAC1 PTEN1 TEP1 |
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) | Genistein results in increased expression of PTEN mRNA |
increases expression
|
mRNA |
15829497
|
| D019833 | 5728 |
PTEN
10q23del BZS CWS1 DEC GLM2 MHAM MMAC1 PTEN1 TEP1 |
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) | Genistein results in increased expression of PTEN protein |
increases expression
|
protein |
15829497
|
| D019833 | 5728 |
PTEN
10q23del BZS CWS1 DEC GLM2 MHAM MMAC1 PTEN1 TEP1 |
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) | [[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased activity of FOXO3 protein |
decreases activity
/ increases activity / increases expression |
protein |
18431742
|
| D019833 | 5728 |
PTEN
10q23del BZS CWS1 DEC GLM2 MHAM MMAC1 PTEN1 TEP1 |
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) | [[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased expression of TP53 protein |
decreases activity
/ increases expression |
protein |
18431742
|
| D019833 | 5731 |
PTGER1
EP1 |
prostaglandin E receptor 1 (subtype EP1), 42kDa | Genistein results in decreased expression of PTGER1 mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 5733 |
PTGER3
EP3 EP3-I EP3-II EP3-III EP3-IV EP3e PGE2-R |
prostaglandin E receptor 3 (subtype EP3) | Genistein results in increased expression of PTGER3 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 145482 |
PTGR2
PGR2 ZADH1 |
prostaglandin reductase 2 (EC:1.3.1.48) | ESR2 promotes the reaction [Genistein results in increased expression of PTGR2 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 145482 |
PTGR2
PGR2 ZADH1 |
prostaglandin reductase 2 (EC:1.3.1.48) | Genistein results in increased expression of PTGR2 protein |
increases expression
|
protein |
20884965
|
| D019833 | 5742 |
PTGS1
COX1 COX3 PCOX1 PES-1 PGG/HS PGHS-1 PGHS1 PHS1 PTGHS |
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Genistein results in decreased expression of PTGS1 mRNA |
decreases expression
|
mRNA |
20816778
|
| D019833 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Capsaicin promotes the reaction [Genistein results in decreased expression of PTGS2 protein] |
decreases expression
/ increases reaction |
protein |
19723084
|
| D019833 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | [Genistein co-treated with arsenic trioxide] results in decreased expression of PTGS2 protein |
affects cotreatment
/ decreases expression |
protein |
21078540
|
| D019833 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | [Genistein co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19347870
|
| D019833 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Genistein inhibits the reaction [Fluorouracil results in increased expression of PTGS2 protein] |
decreases reaction
/ increases expression |
protein |
15896711
|
| D019833 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | [Genistein inhibits the reaction [Fluorouracil results in increased expression of PTGS2 protein]] which results in decreased abundance of Dinoprostone |
decreases abundance
/ decreases reaction / increases expression |
protein |
15896711
|
| D019833 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Genistein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
16870006
|
| D019833 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Genistein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] |
decreases reaction
/ increases expression |
protein |
16870006
|
| D019833 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Genistein inhibits the reaction [TGFA protein results in increased expression of PTGS2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
10783318
|
| D019833 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Genistein results in decreased expression of PTGS2 mRNA |
decreases expression
|
mRNA |
10783318
|
| D019833 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Genistein results in decreased expression of PTGS2 protein |
decreases expression
|
protein |
19723084
21078540 |
| D019833 | 5747 |
PTK2
FADK FAK FAK1 FRNK PPP1R71 p125FAK pp125FAK |
protein tyrosine kinase 2 (EC:2.7.10.2) | Genistein results in increased phosphorylation of PTK2 protein |
increases phosphorylation
|
protein |
12421874
|
| D019833 | 5763 |
PTMS
ParaT |
parathymosin | Genistein results in decreased expression of PTMS mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 80324 |
PUS1
MLASA1 |
pseudouridylate synthase 1 (EC:5.4.99.12) | Genistein results in increased expression of PUS1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 5822 |
PWP2
EHOC-17 PWP2H UTP1 |
PWP2 periodic tryptophan protein homolog (yeast) | Genistein results in decreased expression of PWP2 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 5822 |
PWP2
EHOC-17 PWP2H UTP1 |
PWP2 periodic tryptophan protein homolog (yeast) | Genistein results in increased expression of PWP2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 5834 |
PYGB
GPBB |
phosphorylase, glycogen; brain (EC:2.4.1.1) | ESR2 promotes the reaction [Genistein results in increased expression of PYGB protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 5834 |
PYGB
GPBB |
phosphorylase, glycogen; brain (EC:2.4.1.1) | Genistein results in increased expression of PYGB protein |
increases expression
|
protein |
20884965
|
| D019833 | 5858 |
PZP
CPAMD6 |
pregnancy-zone protein | Genistein results in increased expression of PZP mRNA |
increases expression
|
mRNA |
16705744
|
| D019833 | 54870 |
QRICH1
|
glutamine-rich 1 | Genistein inhibits the reaction [Nocodazole results in increased phosphorylation of QRICH1 protein] |
decreases reaction
/ increases phosphorylation |
protein |
17510977
|
| D019833 | 5768 |
QSOX1
Q6 QSCN6 |
quiescin Q6 sulfhydryl oxidase 1 (EC:1.8.3.2) | Genistein results in increased expression of QSOX1 mRNA |
increases expression
|
mRNA |
20884965
23019147 |
| D019833 | 169714 |
QSOX2
QSCN6L1 SOXN |
quiescin Q6 sulfhydryl oxidase 2 (EC:1.8.3.2) | Genistein results in increased expression of QSOX2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 9230 |
RAB11B
H-YPT3 |
RAB11B, member RAS oncogene family | Genistein results in decreased expression of RAB11B mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 22931 |
RAB18
RAB18LI1 WARBM3 |
RAB18, member RAS oncogene family | ESR2 promotes the reaction [Genistein results in increased expression of RAB18 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 22931 |
RAB18
RAB18LI1 WARBM3 |
RAB18, member RAS oncogene family | Genistein results in increased expression of RAB18 protein |
increases expression
|
protein |
20884965
|
| D019833 | 10244 |
RABEPK
RAB9P40 bA65N13.1 p40 |
Rab9 effector protein with kelch motifs | Genistein results in increased expression of RABEPK mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 29127 |
RACGAP1
CYK4 HsCYK-4 ID-GAP MgcRacGAP |
Rac GTPase activating protein 1 | Genistein results in increased expression of RACGAP1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 5886 |
RAD23A
HHR23A HR23A |
RAD23 homolog A (S. cerevisiae) | Genistein results in decreased expression of RAD23A mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 5888 |
RAD51
BRCC5 HRAD51 HsRad51 HsT16930 MRMV2 RAD51A RECA |
RAD51 recombinase | Genistein results in increased expression of RAD51 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 10635 |
RAD51AP1
PIR51 |
RAD51 associated protein 1 | Genistein results in increased expression of RAD51AP1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 5889 |
RAD51C
BROVCA3 FANCO R51H3 RAD51L2 |
RAD51 paralog C | Genistein results in increased expression of RAD51C mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 5894 |
RAF1
CRAF NS5 Raf-1 c-Raf |
v-raf-1 murine leukemia viral oncogene homolog 1 (EC:2.7.11.1) | Genistein results in increased phosphorylation of RAF1 protein |
increases phosphorylation
|
protein |
19038232
|
| D019833 | 5905 |
RANGAP1
Fug1 RANGAP SD |
Ran GTPase activating protein 1 | Genistein results in decreased expression of RANGAP1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 51195 |
RAPGEFL1
Link-GEFII |
Rap guanine nucleotide exchange factor (GEF)-like 1 | Genistein results in increased expression of RAPGEFL1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 5920 |
RARRES3
HRASLS4 HRSL4 PLA1/2-3 RIG1 TIG3 |
retinoic acid receptor responder (tazarotene induced) 3 | Genistein results in increased expression of RARRES3 mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 22821 |
RASA3
GAP1IP4BP GAPIII |
RAS p21 protein activator 3 | Genistein results in increased expression of RASA3 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 153020 |
RASGEF1B
GPIG4 |
RasGEF domain family, member 1B | Genistein results in decreased expression of RASGEF1B mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 10125 |
RASGRP1
CALDAG-GEFI CALDAG-GEFII RASGRP V hRasGRP1 |
RAS guanyl releasing protein 1 (calcium and DAG-regulated) | Genistein results in increased expression of RASGRP1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 5925 |
RB1
OSRC RB p105-Rb pRb pp110 |
retinoblastoma 1 | Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein |
decreases activity
/ increases phosphorylation |
protein |
17051425
|
| D019833 | 5925 |
RB1
OSRC RB p105-Rb pRb pp110 |
retinoblastoma 1 | lycopene inhibits the reaction [Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein] |
decreases activity
/ decreases reaction / increases phosphorylation |
protein |
17051425
|
| D019833 | 5932 |
RBBP8
COM1 CTIP JWDS RIM SAE2 SCKL2 |
retinoblastoma binding protein 8 | Genistein results in increased expression of RBBP8 mRNA |
increases expression
|
mRNA |
15757668
23019147 |
| D019833 | 31818 | Genistein results in increased expression of RBM13 mRNA |
increases expression
|
mRNA |
19371625
|
||
| D019833 | 5947 |
RBP1
CRABP-I CRBP CRBP1 CRBPI RBPC |
retinol binding protein 1, cellular | Genistein results in decreased expression of RBP1 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 5950 |
RBP4
RDCCAS |
retinol binding protein 4, plasma | Genistein results in increased expression of RBP4 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 5954 |
RCN1
PIG20 RCAL RCN |
reticulocalbin 1, EF-hand calcium binding domain | ESR1 promotes the reaction [Genistein results in increased expression of RCN1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 5954 |
RCN1
PIG20 RCAL RCN |
reticulocalbin 1, EF-hand calcium binding domain | Genistein results in increased expression of RCN1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 7905 |
REEP5
C5orf18 D5S346 DP1 TB2 YOP1 |
receptor accessory protein 5 | ESR2 promotes the reaction [Genistein results in decreased expression of REEP5 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 7905 |
REEP5
C5orf18 D5S346 DP1 TB2 YOP1 |
receptor accessory protein 5 | ESR2 promotes the reaction [Genistein results in increased expression of REEP5 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 7905 |
REEP5
C5orf18 D5S346 DP1 TB2 YOP1 |
receptor accessory protein 5 | Genistein results in decreased expression of REEP5 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 7905 |
REEP5
C5orf18 D5S346 DP1 TB2 YOP1 |
receptor accessory protein 5 | Genistein results in increased expression of REEP5 protein |
increases expression
|
protein |
20884965
|
| D019833 | 5970 |
RELA
NFKB3 p65 |
v-rel avian reticuloendotheliosis viral oncogene homolog A | Genistein affects the localization of RELA protein |
affects localization
|
protein |
18431742
|
| D019833 | 5970 |
RELA
NFKB3 p65 |
v-rel avian reticuloendotheliosis viral oncogene homolog A | Genistein promotes the reaction [arsenic trioxide results in decreased expression of RELA protein] |
decreases expression
/ increases reaction |
protein |
21078540
|
| D019833 | 5970 |
RELA
NFKB3 p65 |
v-rel avian reticuloendotheliosis viral oncogene homolog A | Genistein results in decreased expression of RELA protein |
decreases expression
|
protein |
21078540
|
| D019833 | 6001 |
RGS10
|
regulator of G-protein signaling 10 | Genistein results in increased expression of RGS10 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 6004 |
RGS16
A28-RGS14 A28-RGS14P RGS-R |
regulator of G-protein signaling 16 | Genistein results in decreased expression of RGS16 mRNA |
decreases expression
|
mRNA |
15256057
|
| D019833 | 9886 |
RHOBTB1
|
Rho-related BTB domain containing 1 | Genistein results in increased expression of RHOBTB1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 58480 |
RHOU
ARHU CDC42L1 DJ646B12.2 WRCH1 fJ646B12.2 hG28K |
ras homolog family member U | Genistein results in increased expression of RHOU mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 116028 |
RMI2
BLAP18 C16orf75 |
RecQ mediated genome instability 2 | Genistein results in decreased expression of RMI2 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 246243 |
RNASEH1
H1RNA RNH1 |
ribonuclease H1 (EC:3.1.26.4) | Genistein results in increased expression of RNASEH1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 8635 |
RNASET2
RNASE6PL bA514O12.3 |
ribonuclease T2 (EC:3.1.27.1) | Genistein results in increased expression of RNASET2 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 84900 |
RNFT2
TMEM118 |
ring finger protein, transmembrane 2 | Genistein results in increased expression of RNFT2 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 55178 |
RNMTL1
|
RNA methyltransferase like 1 (EC:2.1.1.-) | ESR2 promotes the reaction [Genistein results in increased expression of RNMTL1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 55178 |
RNMTL1
|
RNA methyltransferase like 1 (EC:2.1.1.-) | Genistein results in increased expression of RNMTL1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 6051 |
RNPEP
|
arginyl aminopeptidase (aminopeptidase B) (EC:3.4.11.6) | ESR2 promotes the reaction [Genistein results in increased expression of RNPEP protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 6051 |
RNPEP
|
arginyl aminopeptidase (aminopeptidase B) (EC:3.4.11.6) | Genistein results in increased expression of RNPEP protein |
increases expression
|
protein |
20884965
|
| D019833 | 83853 |
ROPN1L
ASP RSPH11 |
rhophilin associated tail protein 1-like | Genistein results in increased expression of ROPN1L mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 130773 | ESR1 promotes the reaction [Genistein results in increased expression of RPL23AP37 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
||
| D019833 | 130773 | Genistein results in increased expression of RPL23AP37 protein |
increases expression
|
protein |
20884965
|
||
| D019833 | 6158 |
RPL28
L28 |
ribosomal protein L28 (EC:3.6.5.3) | Genistein results in increased expression of RPL28 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 6169 |
RPL38
L38 |
ribosomal protein L38 | ESR2 promotes the reaction [Genistein results in decreased expression of RPL38 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 6169 |
RPL38
L38 |
ribosomal protein L38 | Genistein results in decreased expression of RPL38 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 6205 |
RPS11
S11 |
ribosomal protein S11 | Genistein results in decreased expression of RPS11 mRNA |
decreases expression
|
mRNA |
15256057
|
| D019833 | 6217 |
RPS16
S16 |
ribosomal protein S16 | ESR1 promotes the reaction [Genistein results in decreased expression of RPS16 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 6217 |
RPS16
S16 |
ribosomal protein S16 | Genistein results in decreased expression of RPS16 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 6222 |
RPS18
D6S218E HKE3 KE-3 KE3 S18 |
ribosomal protein S18 | ESR1 promotes the reaction [Genistein results in decreased expression of RPS18 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 6222 |
RPS18
D6S218E HKE3 KE-3 KE3 S18 |
ribosomal protein S18 | Genistein results in decreased expression of RPS18 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 6223 |
RPS19
DBA DBA1 S19 |
ribosomal protein S19 | Genistein results in decreased expression of RPS19 mRNA |
decreases expression
|
mRNA |
15256057
|
| D019833 | 6230 |
RPS25
S25 |
ribosomal protein S25 | ESR1 promotes the reaction [Genistein results in decreased expression of RPS25 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 6230 |
RPS25
S25 |
ribosomal protein S25 | Genistein results in decreased expression of RPS25 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 6235 |
RPS29
S29 |
ribosomal protein S29 | ESR1 promotes the reaction [Genistein results in decreased expression of RPS29 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 6235 |
RPS29
S29 |
ribosomal protein S29 | Genistein results in decreased expression of RPS29 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 6197 |
RPS6KA3
CLS HU-3 ISPK-1 MAPKAPK1B MRX19 RSK RSK2 S6K-alpha3 p90-RSK2 pp90RSK2 |
ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1) | Genistein results in increased expression of RPS6KA3 mRNA |
increases expression
|
mRNA |
15757668
|
| D019833 | 6236 |
RRAD
RAD RAD1 REM3 |
Ras-related associated with diabetes | Genistein results in decreased expression of RRAD mRNA |
decreases expression
|
mRNA |
15257099
|
| D019833 | 6241 |
RRM2
R2 RR2 RR2M |
ribonucleotide reductase M2 (EC:1.17.4.1) | Genistein results in increased expression of RRM2 mRNA |
increases expression
|
mRNA |
16474171
20884965 |
| D019833 | 50484 |
RRM2B
MTDPS8A MTDPS8B P53R2 |
ribonucleotide reductase M2 B (TP53 inducible) (EC:1.17.4.1) | Genistein results in increased expression of RRM2B mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 23223 |
RRP12
KIAA0690 |
ribosomal RNA processing 12 homolog (S. cerevisiae) | Genistein results in increased expression of RRP12 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 9136 |
RRP9
RNU3IP2 U3-55K |
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) | Genistein results in increased expression of RRP9 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 23212 |
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | Genistein results in decreased expression of RRS1 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 23212 |
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | Genistein results in increased expression of RRS1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 6256 |
RXRA
NR2B1 |
retinoid X receptor, alpha | Genistein promotes the reaction [RXRA protein binds to ABCC2 promoter] |
affects binding
/ increases reaction |
protein |
21689630
|
| D019833 | 6256 |
RXRA
NR2B1 |
retinoid X receptor, alpha | Genistein results in decreased expression of RXRA mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 6256 |
RXRA
NR2B1 |
retinoid X receptor, alpha | resveratrol inhibits the reaction [Genistein promotes the reaction [RXRA protein binds to ABCC2 promoter]] |
affects binding
/ decreases reaction / increases reaction |
protein |
21689630
|
| D019833 | 140576 |
S100A16
DT1P1A7 S100F |
S100 calcium binding protein A16 | ESR2 promotes the reaction [Genistein results in decreased expression of S100A16 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 140576 |
S100A16
DT1P1A7 S100F |
S100 calcium binding protein A16 | Genistein results in decreased expression of S100A16 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 6279 |
S100A8
60B8AG CAGA CFAG CGLA CP-10 L1Ag MA387 MIF MRP8 NIF P8 |
S100 calcium binding protein A8 | ESR1 promotes the reaction [Genistein results in decreased expression of S100A8 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 6279 |
S100A8
60B8AG CAGA CFAG CGLA CP-10 L1Ag MA387 MIF MRP8 NIF P8 |
S100 calcium binding protein A8 | ESR2 promotes the reaction [Genistein results in decreased expression of S100A8 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 6279 |
S100A8
60B8AG CAGA CFAG CGLA CP-10 L1Ag MA387 MIF MRP8 NIF P8 |
S100 calcium binding protein A8 | Genistein results in decreased expression of S100A8 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 6280 |
S100A9
60B8AG CAGB CFAG CGLB L1AG LIAG MAC387 MIF MRP14 NIF P14 |
S100 calcium binding protein A9 | ESR1 promotes the reaction [Genistein results in decreased expression of S100A9 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 6280 |
S100A9
60B8AG CAGB CFAG CGLB L1AG LIAG MAC387 MIF MRP14 NIF P14 |
S100 calcium binding protein A9 | ESR2 promotes the reaction [Genistein results in increased expression of S100A9 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 6280 |
S100A9
60B8AG CAGB CFAG CGLB L1AG LIAG MAC387 MIF MRP14 NIF P14 |
S100 calcium binding protein A9 | Genistein results in decreased expression of S100A9 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 6280 |
S100A9
60B8AG CAGB CFAG CGLB L1AG LIAG MAC387 MIF MRP14 NIF P14 |
S100 calcium binding protein A9 | Genistein results in increased expression of S100A9 protein |
increases expression
|
protein |
20884965
|
| D019833 | 1903 |
S1PR3
EDG-3 EDG3 LPB3 S1P3 |
sphingosine-1-phosphate receptor 3 | Genistein results in increased expression of S1PR3 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 29901 |
SAC3D1
HSU79266 SHD1 |
SAC3 domain containing 1 | Genistein results in increased expression of SAC3D1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 6299 |
SALL1
HSAL1 Sal-1 TBS ZNF794 |
spalt-like transcription factor 1 | Genistein results in increased expression of SALL1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 45384 | Genistein results in decreased expression of SAT mRNA |
decreases expression
|
mRNA |
19371625
|
||
| D019833 | 6309 |
SC5D
ERG3 S5DES SC5DL |
sterol-C5-desaturase (EC:1.14.21.6) | Genistein results in decreased expression of SC5D mRNA |
decreases expression
|
mRNA |
20816778
|
| D019833 | 6319 |
SCD
FADS5 MSTP008 SCD1 SCDOS |
stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) | Genistein results in decreased expression of SCD mRNA |
decreases expression
|
mRNA |
15257099
20816778 |
| D019833 | 6319 |
SCD
FADS5 MSTP008 SCD1 SCDOS |
stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) | Genistein results in increased expression of SCD mRNA |
increases expression
|
mRNA |
15378649
18847459 |
| D019833 | 8796 |
SCEL
|
sciellin | Genistein results in decreased expression of SCEL mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 29970 |
SCHIP1
SCHIP-1 |
schwannomin interacting protein 1 | Genistein results in decreased expression of SCHIP1 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 6334 |
SCN8A
CERIII CIAT EIEE13 MED NaCh6 Nav1.6 PN4 |
sodium channel, voltage gated, type VIII, alpha subunit | Genistein results in decreased expression of SCN8A mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 6390 |
SDHB
CWS2 IP PGL4 SDH SDH1 SDH2 SDHIP |
succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (EC:1.3.5.1) | ESR2 promotes the reaction [Genistein results in decreased expression of SDHB protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 6390 |
SDHB
CWS2 IP PGL4 SDH SDH1 SDH2 SDHIP |
succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (EC:1.3.5.1) | Genistein results in decreased expression of SDHB protein |
decreases expression
|
protein |
20884965
|
| D019833 | 9871 |
SEC24D
|
SEC24 family member D | Genistein results in increased expression of SEC24D mRNA |
increases expression
|
mRNA |
15378649
|
| D019833 | 29927 |
SEC61A1
HSEC61 SEC61 SEC61A |
Sec61 alpha 1 subunit (S. cerevisiae) | Genistein results in decreased expression of SEC61A1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 8991 |
SELENBP1
LPSB SBP56 SP56 hSBP |
selenium binding protein 1 | Genistein results in decreased expression of SELENBP1 mRNA |
decreases expression
|
mRNA |
15159206
|
| D019833 | 22929 |
SEPHS1
SELD SPS SPS1 |
selenophosphate synthetase 1 (EC:2.7.9.3) | ESR1 promotes the reaction [Genistein results in decreased expression of SEPHS1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 22929 |
SEPHS1
SELD SPS SPS1 |
selenophosphate synthetase 1 (EC:2.7.9.3) | ESR2 promotes the reaction [Genistein results in increased expression of SEPHS1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 22929 |
SEPHS1
SELD SPS SPS1 |
selenophosphate synthetase 1 (EC:2.7.9.3) | Genistein results in decreased expression of SEPHS1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 22929 |
SEPHS1
SELD SPS SPS1 |
selenophosphate synthetase 1 (EC:2.7.9.3) | Genistein results in increased expression of SEPHS1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 5265 |
SERPINA1
A1A A1AT AAT PI PI1 PRO2275 alpha1AT |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | Genistein results in decreased expression of SERPINA1 mRNA |
decreases expression
|
mRNA |
18444173
|
| D019833 | 5265 |
SERPINA1
A1A A1AT AAT PI PI1 PRO2275 alpha1AT |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | Genistein results in increased expression of SERPINA1 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 5054 |
SERPINE1
PAI PAI-1 PAI1 PLANH1 |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | Genistein inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein] |
decreases reaction
/ increases secretion |
protein |
14534369
|
| D019833 | 5054 |
SERPINE1
PAI PAI-1 PAI1 PLANH1 |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | Genistein promotes the reaction [troglitazone inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein]] |
decreases reaction
/ increases reaction / increases secretion |
protein |
14534369
|
| D019833 | 27244 |
SESN1
PA26 SEST1 |
sestrin 1 | Genistein results in increased expression of SESN1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 83443 |
SF3B5
SF3b10 Ysf3 |
splicing factor 3b, subunit 5, 10kDa | Genistein results in increased expression of SF3B5 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 6424 |
SFRP4
FRP-4 FRPHE sFRP-4 |
secreted frizzled-related protein 4 | Genistein results in decreased expression of SFRP4 mRNA |
decreases expression
|
mRNA |
15256057
|
| D019833 | 118980 |
SFXN2
|
sideroflexin 2 | Genistein results in increased expression of SFXN2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 6446 |
SGK1
SGK |
serum/glucocorticoid regulated kinase 1 (EC:2.7.11.1) | Genistein inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SGK1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
21056929
|
| D019833 | 6446 |
SGK1
SGK |
serum/glucocorticoid regulated kinase 1 (EC:2.7.11.1) | Genistein results in decreased expression of SGK1 mRNA |
decreases expression
|
mRNA |
21056929
|
| D019833 | 81537 |
SGPP1
SPPase1 |
sphingosine-1-phosphate phosphatase 1 | [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of SGPP1 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
16963248
|
| D019833 | 6462 |
SHBG
ABP SBP TEBG |
sex hormone-binding globulin | Genistein results in increased expression of SHBG mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 6474 |
SHOX2
OG12 OG12X SHOT |
short stature homeobox 2 | Genistein results in decreased expression of SHOX2 mRNA |
decreases expression
|
mRNA |
15256057
|
| D019833 | 6478 |
SIAH2
hSiah2 |
siah E3 ubiquitin protein ligase 2 (EC:6.3.2.-) | Genistein results in increased expression of SIAH2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 23411 |
SIRT1
SIR2L1 |
sirtuin 1 | Genistein affects the localization of SIRT1 protein |
affects localization
|
protein |
18431742
|
| D019833 | 23411 |
SIRT1
SIR2L1 |
sirtuin 1 | Genistein inhibits the reaction [SIRT1 protein binds to FOXO3 promoter] |
affects binding
/ decreases reaction |
protein |
18431742
|
| D019833 | 23411 |
SIRT1
SIR2L1 |
sirtuin 1 | Genistein inhibits the reaction [SIRT1 protein binds to TP53 promoter] |
affects binding
/ decreases reaction |
protein |
18431742
|
| D019833 | 23411 |
SIRT1
SIR2L1 |
sirtuin 1 | [Genistein results in decreased activity of SIRT1 protein] which results in decreased acetylation of HIST3H3 protein |
decreases acetylation
/ decreases activity |
protein |
18431742
|
| D019833 | 23411 |
SIRT1
SIR2L1 |
sirtuin 1 | Genistein results in decreased expression of SIRT1 mRNA |
decreases expression
|
mRNA |
18431742
|
| D019833 | 6558 |
SLC12A2
BSC BSC2 NKCC1 |
solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | Genistein results in decreased expression of SLC12A2 mRNA |
decreases expression
|
mRNA |
15159206
15757668 |
| D019833 | 6560 |
SLC12A4
KCC1 |
solute carrier family 12 (potassium/chloride transporter), member 4 | Genistein results in decreased expression of SLC12A4 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 9123 |
SLC16A3
MCT_3 MCT_4 MCT-3 MCT-4 MCT3 MCT4 |
solute carrier family 16 (monocarboxylate transporter), member 3 | Genistein results in increased expression of SLC16A3 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 6573 |
SLC19A1
CHMD FOLT IFC1 REFC RFC1 |
solute carrier family 19 (folate transporter), member 1 | Genistein results in increased expression of SLC19A1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 6509 |
SLC1A4
ASCT1 SATT |
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | Genistein results in increased expression of SLC1A4 mRNA |
increases expression
|
mRNA |
15757668
|
| D019833 | 6510 |
SLC1A5
AAAT ASCT2 ATBO M7V1 M7VS1 R16 RDRC |
solute carrier family 1 (neutral amino acid transporter), member 5 | Genistein results in increased expression of SLC1A5 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 51310 |
SLC22A17
24p3R BOCT BOIT NGALR NGALR2 NGALR3 hBOIT |
solute carrier family 22, member 17 | Genistein results in increased expression of SLC22A17 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 6584 |
SLC22A5
CDSP OCTN2 OCTN2VT |
solute carrier family 22 (organic cation/carnitine transporter), member 5 | Genistein results in increased expression of SLC22A5 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 9962 |
SLC23A2
NBTL1 SLC23A1 SVCT2 YSPL2 |
solute carrier family 23 (ascorbic acid transporter), member 2 | Genistein inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid] |
decreases reaction
/ increases uptake |
protein |
17092984
|
| D019833 | 60386 |
SLC25A19
DNC MCPHA MUP1 THMD3 THMD4 TPC |
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 | Genistein results in increased expression of SLC25A19 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 79751 |
SLC25A22
EIEE3 GC1 NET44 |
solute carrier family 25 (mitochondrial carrier: glutamate), member 22 | Genistein results in increased expression of SLC25A22 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 115111 |
SLC26A7
SUT2 |
solute carrier family 26 (anion exchanger), member 7 | Genistein results in decreased expression of SLC26A7 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 6513 |
SLC2A1
DYT17 DYT18 DYT9 EIG12 GLUT GLUT1 GLUT1DS HTLVR PED |
solute carrier family 2 (facilitated glucose transporter), member 1 | Genistein inhibits the reaction [SLC2A1 protein affects the transport of Glucose] |
affects transport
/ decreases reaction |
protein |
14642735
|
| D019833 | 6513 |
SLC2A1
DYT17 DYT18 DYT9 EIG12 GLUT GLUT1 GLUT1DS HTLVR PED |
solute carrier family 2 (facilitated glucose transporter), member 1 | Genistein results in decreased activity of SLC2A1 protein |
decreases activity
|
protein |
14642735
|
| D019833 | 7779 |
SLC30A1
ZNT1 ZRC1 |
solute carrier family 30 (zinc transporter), member 1 | Genistein results in increased expression of SLC30A1 mRNA |
increases expression
|
mRNA |
18847459
23019147 |
| D019833 | 1317 |
SLC31A1
COPT1 CTR1 |
solute carrier family 31 (copper transporter), member 1 | Genistein results in increased expression of SLC31A1 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 64116 |
SLC39A8
BIGM103 LZT-Hs6 ZIP8 |
solute carrier family 39 (zinc transporter), member 8 | Genistein results in increased expression of SLC39A8 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 6520 |
SLC3A2
4F2 4F2HC 4T2HC CD98 CD98HC MDU1 NACAE |
solute carrier family 3 (amino acid transporter heavy chain), member 2 | ESR1 promotes the reaction [Genistein results in increased expression of SLC3A2 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 6520 |
SLC3A2
4F2 4F2HC 4T2HC CD98 CD98HC MDU1 NACAE |
solute carrier family 3 (amino acid transporter heavy chain), member 2 | Genistein results in increased expression of SLC3A2 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 6520 |
SLC3A2
4F2 4F2HC 4T2HC CD98 CD98HC MDU1 NACAE |
solute carrier family 3 (amino acid transporter heavy chain), member 2 | Genistein results in increased expression of SLC3A2 protein |
increases expression
|
protein |
20884965
|
| D019833 | 146802 |
SLC47A2
MATE2 MATE2-B MATE2-K MATE2K |
solute carrier family 47 (multidrug and toxin extrusion), member 2 | Genistein results in increased expression of SLC47A2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 6528 |
SLC5A5
NIS TDH1 |
solute carrier family 5 (sodium/iodide cotransporter), member 5 | Genistein results in increased expression of SLC5A5 mRNA |
increases expression
|
mRNA |
21738342
|
| D019833 | 8884 |
SLC5A6
SMVT |
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | Genistein results in increased expression of SLC5A6 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 6539 |
SLC6A12
BGT-1 BGT1 GAT2 |
solute carrier family 6 (neurotransmitter transporter), member 12 | Genistein results in increased expression of SLC6A12 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 11254 |
SLC6A14
BMIQ11 |
solute carrier family 6 (amino acid transporter), member 14 | Genistein results in increased expression of SLC6A14 mRNA |
increases expression
|
mRNA |
11331657
16474171 |
| D019833 | 6533 |
SLC6A6
TAUT |
solute carrier family 6 (neurotransmitter transporter), member 6 | Genistein results in increased expression of SLC6A6 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 23657 |
SLC7A11
CCBR1 xCT |
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | Genistein results in decreased expression of SLC7A11 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 8140 |
SLC7A5
4F2LC CD98 D16S469E E16 LAT1 MPE16 hLAT1 |
solute carrier family 7 (amino acid transporter light chain, L system), member 5 | ESR1 promotes the reaction [Genistein results in increased expression of SLC7A5 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 8140 |
SLC7A5
4F2LC CD98 D16S469E E16 LAT1 MPE16 hLAT1 |
solute carrier family 7 (amino acid transporter light chain, L system), member 5 | Genistein results in increased expression of SLC7A5 mRNA |
increases expression
|
mRNA |
15757668
23019147 |
| D019833 | 8140 |
SLC7A5
4F2LC CD98 D16S469E E16 LAT1 MPE16 hLAT1 |
solute carrier family 7 (amino acid transporter light chain, L system), member 5 | Genistein results in increased expression of SLC7A5 protein |
increases expression
|
protein |
20884965
|
| D019833 | 81893 |
SLC7A5P1
DC49 LAT1-3TM MLAS hLAT1-3TM |
solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1 | Genistein results in increased expression of SLC7A5P1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 387254 |
SLC7A5P2
IMAA MMAA |
solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2 | Genistein results in increased expression of SLC7A5P2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 9368 |
SLC9A3R1
EBP50 NHERF NHERF-1 NHERF1 NPHLOP2 |
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | ESR2 promotes the reaction [Genistein results in increased expression of SLC9A3R1 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 9368 |
SLC9A3R1
EBP50 NHERF NHERF-1 NHERF1 NPHLOP2 |
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | Genistein results in increased expression of SLC9A3R1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 9368 |
SLC9A3R1
EBP50 NHERF NHERF-1 NHERF1 NPHLOP2 |
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | Genistein results in increased expression of SLC9A3R1 protein |
increases expression
|
protein |
20884965
|
| D019833 | 6578 |
SLCO2A1
MATR1 OATP2A1 PGT PHOAR2 SLC21A2 |
solute carrier organic anion transporter family, member 2A1 | Genistein results in increased expression of SLCO2A1 mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 162394 |
SLFN5
|
schlafen family member 5 | Genistein results in increased expression of SLFN5 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 6586 |
SLIT3
MEGF5 SLIL2 SLIT1 Slit-3 slit2 |
slit homolog 3 (Drosophila) | Genistein results in increased expression of SLIT3 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 9748 |
SLK
LOSK STK2 bA16H23.1 se20-9 |
STE20-like kinase (EC:2.7.11.1) | ESR2 promotes the reaction [Genistein results in decreased expression of SLK protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 9748 |
SLK
LOSK STK2 bA16H23.1 se20-9 |
STE20-like kinase (EC:2.7.11.1) | Genistein results in decreased expression of SLK protein |
decreases expression
|
protein |
20884965
|
| D019833 | 57228 |
SMAGP
hSMAGP |
small cell adhesion glycoprotein | Genistein results in decreased expression of SMAGP mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 6597 |
SMARCA4
BAF190 BAF190A BRG1 MRD16 RTPS2 SNF2 SNF2L4 SNF2LB SWI2 hSNF2b |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | Genistein results in increased expression of SMARCA4 mRNA |
increases expression
|
mRNA |
16705744
|
| D019833 | 10592 |
SMC2
CAP-E CAPE SMC-2 SMC2L1 |
structural maintenance of chromosomes 2 | Genistein results in increased expression of SMC2 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 10051 |
SMC4
CAP-C CAPC SMC-4 SMC4L1 hCAP-C |
structural maintenance of chromosomes 4 | Genistein results in increased expression of SMC4 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 23137 |
SMC5
SMC5L1 |
structural maintenance of chromosomes 5 | Genistein results in decreased expression of SMC5 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 23049 |
SMG1
61E3.4 ATX LIP |
SMG1 phosphatidylinositol 3-kinase-related kinase (EC:2.7.11.1) | Genistein results in decreased expression of SMG1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 23049 |
SMG1
61E3.4 ATX LIP |
SMG1 phosphatidylinositol 3-kinase-related kinase (EC:2.7.11.1) | Genistein results in increased expression of SMG1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 201895 |
SMIM14
C4orf34 |
small integral membrane protein 14 | Genistein results in decreased expression of SMIM14 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 54498 |
SMOX
C20orf16 PAO PAO-1 PAOH1 SMO |
spermine oxidase (EC:1.5.3.16) | Genistein results in increased expression of SMOX mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 724102 |
SNHG4
NCRNA00059 U19H |
small nucleolar RNA host gene 4 (non-protein coding) | Genistein results in increased expression of SNHG4 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 677838 |
SNORA61
ACA61 |
small nucleolar RNA, H/ACA box 61 | Genistein results in increased expression of SNORA61 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 6043 |
SNORA63
E3 E3-2 RNE3 RNU107 |
small nucleolar RNA, H/ACA box 63 | Genistein results in increased expression of SNORA63 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 6626 |
SNRPA
Mud1 U1-A U1A |
small nuclear ribonucleoprotein polypeptide A | Genistein results in decreased expression of SNRPA mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 9021 |
SOCS3
ATOD4 CIS3 Cish3 SOCS-3 SSI-3 SSI3 |
suppressor of cytokine signaling 3 | fulvestrant inhibits the reaction [Genistein results in increased expression of SOCS3 mRNA] |
decreases reaction
/ increases expression |
mRNA |
16055089
|
| D019833 | 9021 |
SOCS3
ATOD4 CIS3 Cish3 SOCS-3 SSI-3 SSI3 |
suppressor of cytokine signaling 3 | Genistein results in increased expression of SOCS3 mRNA |
increases expression
|
mRNA |
16055089
|
| D019833 | 6647 |
SOD1
ALS ALS1 IPOA SOD hSod1 homodimer |
superoxide dismutase 1, soluble (EC:1.15.1.1) | Genistein results in increased expression of SOD1 mRNA |
increases expression
|
mRNA |
18686095
|
| D019833 | 6648 |
SOD2
IPOB MNSOD MVCD6 |
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) | Genistein inhibits the reaction [TNF protein results in increased activity of SOD2 protein] |
decreases reaction
/ increases activity |
protein |
9372618
|
| D019833 | 6648 |
SOD2
IPOB MNSOD MVCD6 |
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) | Genistein inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
9372618
|
| D019833 | 6648 |
SOD2
IPOB MNSOD MVCD6 |
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) | Genistein results in decreased expression of SOD2 mRNA |
decreases expression
|
mRNA |
20816778
|
| D019833 | 6649 |
SOD3
EC-SOD |
superoxide dismutase 3, extracellular (EC:1.15.1.1) | Genistein results in decreased expression of SOD3 mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 10580 |
SORBS1
CAP FLAF2 R85FL SH3D5 SH3P12 SORB1 |
sorbin and SH3 domain containing 1 | Genistein results in increased expression of SORBS1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 6652 |
SORD
SORD1 |
sorbitol dehydrogenase (EC:1.1.1.14) | Genistein results in decreased expression of SORD mRNA |
decreases expression
|
mRNA |
15378649
|
| D019833 | 6657 |
SOX2
ANOP3 MCOPS3 |
SRY (sex determining region Y)-box 2 | Genistein results in decreased expression of SOX2 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 6659 |
SOX4
EVI16 |
SRY (sex determining region Y)-box 4 | Genistein results in decreased expression of SOX4 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 6667 |
SP1
|
Sp1 transcription factor | Genistein promotes the reaction [SP1 protein binds to VDR promoter] |
affects binding
/ increases reaction |
protein |
17088408
|
| D019833 | 6667 |
SP1
|
Sp1 transcription factor | Genistein results in increased activity of SP1 protein |
increases activity
|
protein |
17088408
|
| D019833 | 6667 |
SP1
|
Sp1 transcription factor | U 0126 inhibits the reaction [Genistein results in increased activity of SP1 protein] |
decreases reaction
/ increases activity |
protein |
17088408
|
| D019833 | 79582 |
SPAG16
PF20 WDR29 |
sperm associated antigen 16 | Genistein results in decreased expression of SPAG16 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 10615 |
SPAG5
DEEPEST MAP126 hMAP126 |
sperm associated antigen 5 | Genistein affects the expression of SPAG5 mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 124044 |
SPATA2L
C16orf76 tamo |
spermatogenesis associated 2-like | Genistein results in decreased expression of SPATA2L mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 25803 |
SPDEF
PDEF RP11-375E1__A.3 bA375E1.3 |
SAM pointed domain containing ETS transcription factor | Genistein results in decreased expression of SPDEF mRNA |
decreases expression
|
mRNA |
15378649
|
| D019833 | 10927 |
SPIN1
SPIN |
spindlin 1 | Genistein results in decreased expression of SPIN1 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 90864 |
SPSB3
C16orf31 SSB3 |
splA/ryanodine receptor domain and SOCS box containing 3 | Genistein results in decreased expression of SPSB3 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 6713 |
SQLE
|
squalene epoxidase (EC:1.14.13.132) | Genistein results in decreased expression of SQLE mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 8878 |
SQSTM1
A170 OSIL PDB3 ZIP3 p60 p62 p62B |
sequestosome 1 | Genistein results in decreased expression of SQSTM1 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 136853 |
SRCRB4D
S4D-SRCRB SRCRB-S4D SSC4D |
scavenger receptor cysteine rich domain containing, group B (4 domains) | Genistein results in decreased expression of SRCRB4D mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 6716 |
SRD5A2
|
steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC:1.3.1.22) | Genistein results in decreased expression of SRD5A2 mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 79644 |
SRD5A3
CDG1P CDG1Q KRIZI SRD5A2L SRD5A2L1 |
steroid 5 alpha-reductase 3 (EC:1.3.1.22 1.3.1.94) | Genistein results in increased expression of SRD5A3 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 6723 |
SRM
PAPT SPDSY SPS1 SRML1 |
spermidine synthase (EC:2.5.1.16) | Genistein results in increased expression of SRM mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 6734 |
SRPR
DP Sralpha |
signal recognition particle receptor (docking protein) | ESR2 promotes the reaction [Genistein results in decreased expression of SRPR protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 6734 |
SRPR
DP Sralpha |
signal recognition particle receptor (docking protein) | Genistein results in decreased expression of SRPR protein |
decreases expression
|
protein |
20884965
|
| D019833 | 140809 |
SRXN1
C20orf139 Npn3 SRX SRX1 |
sulfiredoxin 1 (EC:1.8.98.2) | Genistein results in increased expression of SRXN1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 6770 |
STAR
STARD1 |
steroidogenic acute regulatory protein | Genistein results in increased expression of STAR mRNA |
increases expression
|
mRNA |
16705744
|
| D019833 | 6772 |
STAT1
CANDF7 ISGF-3 STAT91 |
signal transducer and activator of transcription 1, 91kDa | ESR2 promotes the reaction [Genistein results in decreased expression of STAT1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 6772 |
STAT1
CANDF7 ISGF-3 STAT91 |
signal transducer and activator of transcription 1, 91kDa | Genistein results in decreased expression of STAT1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 6774 |
STAT3
APRF HIES |
signal transducer and activator of transcription 3 (acute-phase response factor) | Genistein inhibits the reaction [Hydrogen Peroxide affects the localization of STAT3 protein] |
affects localization
/ decreases reaction |
protein |
10364193
|
| D019833 | 6774 |
STAT3
APRF HIES |
signal transducer and activator of transcription 3 (acute-phase response factor) | Genistein results in decreased expression of STAT3 mRNA |
decreases expression
|
mRNA |
20816778
|
| D019833 | 6781 |
STC1
STC |
stanniocalcin 1 | [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of STC1 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
16963248
|
| D019833 | 8614 |
STC2
STC-2 STCRP |
stanniocalcin 2 | Genistein results in increased expression of STC2 mRNA |
increases expression
|
mRNA |
16474171
23019147 |
| D019833 | 26872 |
STEAP1
PRSS24 STEAP |
six transmembrane epithelial antigen of the prostate 1 | Genistein results in decreased expression of STEAP1 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 55240 |
STEAP3
AHMIO2 STMP3 TSAP6 dudlin-2 |
STEAP family member 3, metalloreductase | Genistein results in increased expression of STEAP3 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 27347 |
STK39
DCHT PASK SPAK |
serine threonine kinase 39 (EC:2.7.11.1) | Genistein results in decreased expression of STK39 mRNA |
decreases expression
|
mRNA |
15378649
16865672 |
| D019833 | 3925 |
STMN1
C1orf215 LAP18 Lag OP18 PP17 PP19 PR22 SMN |
stathmin 1 | Genistein results in increased expression of STMN1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 6812 |
STXBP1
MUNC18-1 NSEC1 P67 RBSEC1 UNC18 |
syntaxin binding protein 1 | Genistein results in increased expression of STXBP1 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 55959 |
SULF2
HSULF-2 |
sulfatase 2 | Genistein results in increased expression of SULF2 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 6817 |
SULT1A1
HAST1/HAST2 P-PST PST ST1A1 ST1A3 STP STP1 TSPST1 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) | Genistein inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol] |
decreases reaction
/ increases sulfation |
protein |
15531517
|
| D019833 | 6818 |
SULT1A3
HAST HAST3 M-PST ST1A3/ST1A4 ST1A5 STM TL-PST |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) | Genistein inhibits the reaction [SULT1A3 protein results in increased sulfation of Dopamine] |
decreases reaction
/ increases sulfation |
protein |
15531517
|
| D019833 | 6783 |
SULT1E1
EST EST-1 ST1E1 STE |
sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4) | Genistein results in decreased activity of SULT1E1 protein |
decreases activity
|
protein |
16914110
|
| D019833 | 6783 |
SULT1E1
EST EST-1 ST1E1 STE |
sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4) | Genistein results in decreased expression of SULT1E1 mRNA |
decreases expression
|
mRNA |
18634814
|
| D019833 | 6783 |
SULT1E1
EST EST-1 ST1E1 STE |
sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4) | Genistein results in decreased expression of SULT1E1 protein |
decreases expression
|
protein |
18634814
|
| D019833 | 6836 |
SURF4
ERV29 |
surfeit 4 | Genistein results in decreased expression of SURF4 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 203328 |
SUSD3
|
sushi domain containing 3 | Genistein results in increased expression of SUSD3 mRNA |
increases expression
|
mRNA |
20884965
|
| D019833 | 94056 |
SYAP1
|
synapse associated protein 1 | ESR1 promotes the reaction [Genistein results in decreased expression of SYAP1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 94056 |
SYAP1
|
synapse associated protein 1 | Genistein results in decreased expression of SYAP1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 8871 |
SYNJ2
INPP5H |
synaptojanin 2 (EC:3.1.3.36) | Genistein results in increased expression of SYNJ2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 10460 |
TACC3
ERIC-1 ERIC1 |
transforming, acidic coiled-coil containing protein 3 | Genistein results in increased expression of TACC3 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 6870 |
TACR3
HH11 NK-3R NK3R NKR TAC3RL |
tachykinin receptor 3 | [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of TACR3 mRNA |
affects cotreatment
/ increases expression |
mRNA |
16963248
|
| D019833 | 4070 |
TACSTD2
EGP-1 EGP1 GA733-1 GA7331 GP50 M1S1 TROP2 |
tumor-associated calcium signal transducer 2 | Genistein results in increased expression of TACSTD2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 22980 |
TCF25
Hulp1 NULP1 PRO2620 hKIAA1049 |
transcription factor 25 (basic helix-loop-helix) | Genistein results in decreased expression of TCF25 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 6925 |
TCF4
E2-2 ITF-2 ITF2 PTHS SEF-2 SEF2 SEF2-1 SEF2-1A SEF2-1B TCF-4 bHLHb19 |
transcription factor 4 | Genistein results in decreased expression of TCF4 mRNA |
decreases expression
|
mRNA |
15256057
|
| D019833 | 7005 |
TEAD3
DTEF-1 ETFR-1 TEAD-3 TEAD5 TEF-5 TEF5 |
TEA domain family member 3 | Genistein results in decreased expression of TEAD3 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 9894 |
TELO2
CLK2 TEL2 |
telomere maintenance 2 | Genistein results in decreased expression of TELO2 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 7015 |
TERT
CMM9 DKCA2 DKCB4 EST2 PFBMFT1 TCS1 TP2 TRT hEST2 hTRT |
telomerase reverse transcriptase (EC:2.7.7.49) | Genistein results in decreased expression of TERT mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 7031 |
TFF1
BCEI D21S21 HP1.A HPS2 pNR-2 pS2 |
trefoil factor 1 | ESR1 protein inhibits the reaction [Genistein results in increased expression of TFF1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
23384675
|
| D019833 | 7031 |
TFF1
BCEI D21S21 HP1.A HPS2 pNR-2 pS2 |
trefoil factor 1 | fulvestrant inhibits the reaction [Genistein results in increased expression of TFF1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
22562034
|
| D019833 | 7031 |
TFF1
BCEI D21S21 HP1.A HPS2 pNR-2 pS2 |
trefoil factor 1 | Genistein results in increased expression of TFF1 mRNA |
increases expression
|
mRNA |
11331657
11368622 15090535 16474171 22562034 23384675 |
| D019833 | 7033 |
TFF3
ITF P1B TFI |
trefoil factor 3 (intestinal) | Genistein results in increased expression of TFF3 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 7035 |
TFPI
EPI LACI TFI TFPI1 |
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | Genistein results in decreased expression of TFPI mRNA |
decreases expression
|
mRNA |
18847459
|
| D019833 | 7037 |
TFRC
CD71 T9 TFR TFR1 TR TRFR p90 |
transferrin receptor | ESR2 promotes the reaction [Genistein results in increased expression of TFRC protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 7037 |
TFRC
CD71 T9 TFR TFR1 TR TRFR p90 |
transferrin receptor | Genistein results in increased expression of TFRC protein |
increases expression
|
protein |
20884965
|
| D019833 | 7039 |
TGFA
TFGA |
transforming growth factor, alpha | Genistein inhibits the reaction [TGFA protein results in increased expression of PTGS2 mRNA] |
decreases reaction
/ increases expression |
protein |
10783318
|
| D019833 | 7039 |
TGFA
TFGA |
transforming growth factor, alpha | Genistein results in increased expression of TGFA mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 7040 |
TGFB1
CED DPD1 LAP TGFB TGFbeta |
transforming growth factor, beta 1 | Genistein results in decreased expression of TGFB1 mRNA |
decreases expression
|
mRNA |
20816778
|
| D019833 | 7042 |
TGFB2
LDS4 TGF-beta2 |
transforming growth factor, beta 2 | Genistein results in decreased expression of TGFB2 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 7043 |
TGFB3
ARVD ARVD1 TGF-beta3 |
transforming growth factor, beta 3 | Genistein results in increased expression of TGFB3 mRNA |
increases expression
|
mRNA |
11331657
|
| D019833 | 7057 |
THBS1
THBS THBS-1 TSP TSP-1 TSP1 |
thrombospondin 1 | Genistein results in increased expression of THBS1 mRNA |
increases expression
|
mRNA |
16474171
19371625 |
| D019833 | 51337 |
THEM6
C8orf55 DSCD75 |
thioesterase superfamily member 6 | Genistein results in increased expression of THEM6 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 57187 |
THOC2
CXorf3 THO2 dJ506G2.1 hTREX120 |
THO complex 2 | ESR1 promotes the reaction [Genistein results in decreased expression of THOC2 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 57187 |
THOC2
CXorf3 THO2 dJ506G2.1 hTREX120 |
THO complex 2 | Genistein results in decreased expression of THOC2 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 7072 |
TIA1
TIA-1 WDM |
TIA1 cytotoxic granule-associated RNA binding protein | Genistein results in increased expression of TIA1 mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 9220 |
TIAF1
MAJN SPR210 |
TGFB1-induced anti-apoptotic factor 1 | Genistein results in increased expression of TIAF1 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 26515 |
TIMM10B
FXC1 TIM10B Tim9b |
translocase of inner mitochondrial membrane 10 homolog B (yeast) | ESR1 promotes the reaction [Genistein results in decreased expression of TIMM10B protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 26515 |
TIMM10B
FXC1 TIM10B Tim9b |
translocase of inner mitochondrial membrane 10 homolog B (yeast) | Genistein results in decreased expression of TIMM10B protein |
decreases expression
|
protein |
20884965
|
| D019833 | 7076 |
TIMP1
CLGI EPA EPO HCI TIMP |
TIMP metallopeptidase inhibitor 1 | Genistein inhibits the reaction [Chromium results in increased expression of TIMP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15878362
|
| D019833 | 7076 |
TIMP1
CLGI EPA EPO HCI TIMP |
TIMP metallopeptidase inhibitor 1 | Genistein inhibits the reaction [Cobalt results in increased expression of TIMP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15878362
|
| D019833 | 7076 |
TIMP1
CLGI EPA EPO HCI TIMP |
TIMP metallopeptidase inhibitor 1 | Genistein inhibits the reaction [Phosphorylcholine analog results in increased expression of TIMP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15878362
|
| D019833 | 7076 |
TIMP1
CLGI EPA EPO HCI TIMP |
TIMP metallopeptidase inhibitor 1 | Genistein results in decreased expression of TIMP1 mRNA |
decreases expression
|
mRNA |
15754008
|
| D019833 | 7077 |
TIMP2
CSC-21K DDC8 |
TIMP metallopeptidase inhibitor 2 | Genistein results in decreased expression of TIMP2 mRNA |
decreases expression
|
mRNA |
15754008
|
| D019833 | 7078 |
TIMP3
HSMRK222 K222 K222TA2 SFD |
TIMP metallopeptidase inhibitor 3 | Genistein results in decreased expression of TIMP3 mRNA |
decreases expression
|
mRNA |
15754008
16474171 |
| D019833 | 26277 |
TINF2
DKCA3 TIN2 |
TERF1 (TRF1)-interacting nuclear factor 2 | Genistein results in decreased expression of TINF2 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 7083 |
TK1
TK2 |
thymidine kinase 1, soluble (EC:2.7.1.21) | Genistein results in increased expression of TK1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 7086 |
TKT
TK TKT1 |
transketolase (EC:2.2.1.1) | Genistein results in decreased expression of TKT mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 7093 |
TLL2
|
tolloid-like 2 | Genistein results in increased expression of TLL2 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 9911 |
TMCC2
HUCEP11 |
transmembrane and coiled-coil domain family 2 | Genistein results in decreased expression of TMCC2 mRNA |
decreases expression
|
mRNA |
18444173
|
| D019833 | 54732 |
TMED9
GMP25 HSGP25L2G p25 |
transmembrane emp24 protein transport domain containing 9 | Genistein results in decreased expression of TMED9 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 83862 |
TMEM120A
NET29 TMPIT |
transmembrane protein 120A | ESR1 promotes the reaction [Genistein results in increased expression of TMEM120A protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 83862 |
TMEM120A
NET29 TMPIT |
transmembrane protein 120A | Genistein results in increased expression of TMEM120A protein |
increases expression
|
protein |
20884965
|
| D019833 | 80757 |
TMEM121
hole |
transmembrane protein 121 | Genistein results in decreased expression of TMEM121 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 135932 |
TMEM139
|
transmembrane protein 139 | Genistein results in decreased expression of TMEM139 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 55151 |
TMEM38B
C9orf87 D4Ertd89e OI14 TRIC-B TRICB bA219P18.1 |
transmembrane protein 38B | Genistein results in increased expression of TMEM38B mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 55287 |
TMEM40
|
transmembrane protein 40 | Genistein results in decreased expression of TMEM40 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 120224 |
TMEM45B
|
transmembrane protein 45B | Genistein results in decreased expression of TMEM45B mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 113452 |
TMEM54
BCLP CAC-1 CAC1 |
transmembrane protein 54 | Genistein results in decreased expression of TMEM54 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 27346 |
TMEM97
MAC30 |
transmembrane protein 97 | Genistein results in increased expression of TMEM97 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 7112 |
TMPO
CMD1T LAP2 LEMD4 PRO0868 TP |
thymopoietin | Genistein results in increased expression of TMPO mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 7113 |
TMPRSS2
PP9284 PRSS10 |
transmembrane protease, serine 2 (EC:3.4.21.-) | Genistein results in decreased expression of TMPRSS2 mRNA |
decreases expression
|
mRNA |
15378649
|
| D019833 | 83857 |
TMTC1
OLF TMTC1A |
transmembrane and tetratricopeptide repeat containing 1 | Genistein results in decreased expression of TMTC1 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | fulvestrant inhibits the reaction [Genistein inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]] |
decreases reaction
/ increases expression |
protein |
12547825
|
| D019833 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA] |
affects cotreatment
/ decreases reaction / increases expression |
mRNA |
15779068
|
| D019833 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Genistein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein] |
affects cotreatment
/ decreases reaction / increases expression |
protein |
15779068
|
| D019833 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Genistein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] |
decreases reaction
/ increases expression |
mRNA |
10653605
|
| D019833 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Genistein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] |
decreases reaction
/ increases expression |
protein |
10653605
|
| D019833 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Genistein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA] |
decreases reaction
/ increases expression |
mRNA |
17934341
|
| D019833 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Genistein inhibits the reaction [Tetrachlorodibenzodioxin results in increased secretion of TNF protein] |
decreases reaction
/ increases secretion |
protein |
17934341
|
| D019833 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Genistein inhibits the reaction [TNF protein results in increased activity of SOD2 protein] |
decreases reaction
/ increases activity |
protein |
9372618
|
| D019833 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Genistein inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA] |
decreases reaction
/ increases expression |
protein |
9372618
|
| D019833 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Genistein inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] |
decreases reaction
/ increases expression |
protein |
12547825
|
| D019833 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Genistein inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein] |
decreases reaction
/ increases secretion |
protein |
14534369
|
| D019833 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Genistein promotes the reaction [troglitazone inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein]] |
decreases reaction
/ increases reaction / increases secretion |
protein |
14534369
|
| D019833 | 7130 |
TNFAIP6
TSG-6 TSG6 |
tumor necrosis factor, alpha-induced protein 6 | [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of TNFAIP6 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
16963248
|
| D019833 | 25816 |
TNFAIP8
GG2-1 MDC-3.13 NDED SCC-S2 SCCS2 |
tumor necrosis factor, alpha-induced protein 8 | Genistein results in decreased expression of TNFAIP8 mRNA |
decreases expression
|
mRNA |
15378649
|
| D019833 | 8795 |
TNFRSF10B
CD262 DR5 KILLER KILLER/DR5 TRAIL-R2 TRAILR2 TRICK2 TRICK2A TRICK2B TRICKB ZTNFR9 |
tumor necrosis factor receptor superfamily, member 10b | Genistein results in decreased expression of TNFRSF10B mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 4982 |
TNFRSF11B
OCIF OPG TR1 |
tumor necrosis factor receptor superfamily, member 11b | Genistein results in increased expression of TNFRSF11B mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 51330 |
TNFRSF12A
CD266 FN14 TWEAKR |
tumor necrosis factor receptor superfamily, member 12A | Genistein results in decreased expression of TNFRSF12A mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 7132 |
TNFRSF1A
CD120a FPF MS5 TBP1 TNF-R TNF-R-I TNF-R55 TNFAR TNFR1 TNFR1-d2 TNFR55 TNFR60 p55 p55-R p60 |
tumor necrosis factor receptor superfamily, member 1A | [Genistein co-treated with trichostatin A] results in increased expression of TNFRSF1A mRNA |
affects cotreatment
/ increases expression |
mRNA |
22626855
|
| D019833 | 7132 |
TNFRSF1A
CD120a FPF MS5 TBP1 TNF-R TNF-R-I TNF-R55 TNFAR TNFR1 TNFR1-d2 TNFR55 TNFR60 p55 p55-R p60 |
tumor necrosis factor receptor superfamily, member 1A | [Genistein co-treated with trichostatin A] results in increased expression of TNFRSF1A protein |
affects cotreatment
/ increases expression |
protein |
22626855
|
| D019833 | 8718 |
TNFRSF25
APO-3 DDR3 DR3 LARD TNFRSF12 TR3 TRAMP WSL-1 WSL-LR |
tumor necrosis factor receptor superfamily, member 25 | Genistein results in decreased expression of TNFRSF25 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 8718 |
TNFRSF25
APO-3 DDR3 DR3 LARD TNFRSF12 TR3 TRAMP WSL-1 WSL-LR |
tumor necrosis factor receptor superfamily, member 25 | Genistein results in increased expression of TNFRSF25 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone results in decreased susceptibility to [Genistein co-treated with TNFSF10 protein] |
affects cotreatment
/ decreases response to substance |
protein |
19497411
|
| D019833 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone analog results in decreased susceptibility to [Genistein co-treated with TNFSF10 protein] |
affects cotreatment
/ decreases response to substance |
protein |
19497411
|
| D019833 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone results in decreased susceptibility to [Genistein co-treated with TNFSF10 protein] |
affects cotreatment
/ decreases response to substance |
protein |
19497411
|
| D019833 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | benzyloxycarbonyl-valyl-alanyl-aspartic acid analog results in decreased susceptibility to [Genistein co-treated with TNFSF10 protein] |
affects cotreatment
/ decreases response to substance |
protein |
19497411
|
| D019833 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | [Genistein co-treated with TNFSF10 protein] results in decreased expression of BCL2 protein |
affects cotreatment
/ decreases expression |
protein |
19497411
|
| D019833 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | [Genistein co-treated with TNFSF10 protein] results in decreased expression of XIAP protein |
affects cotreatment
/ decreases expression |
protein |
19497411
|
| D019833 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | [Genistein co-treated with TNFSF10 protein] results in increased activity of CASP3 protein |
affects cotreatment
/ increases activity |
protein |
19497411
|
| D019833 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | [Genistein co-treated with TNFSF10 protein] results in increased activity of CASP8 protein |
affects cotreatment
/ increases activity |
protein |
19497411
|
| D019833 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | [Genistein co-treated with TNFSF10 protein] results in increased activity of CASP9 protein |
affects cotreatment
/ increases activity |
protein |
19497411
|
| D019833 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | [Genistein co-treated with TNFSF10 protein] results in increased cleavage of BID protein |
affects cotreatment
/ increases cleavage |
protein |
19497411
|
| D019833 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | [Genistein co-treated with TNFSF10 protein] results in increased expression of BAX protein |
affects cotreatment
/ increases expression |
protein |
19497411
|
| D019833 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | Genistein results in increased susceptibility to TNFSF10 protein |
increases response to substance
|
protein |
19497411
|
| D019833 | 7292 |
TNFSF4
CD134L CD252 GP34 OX-40L OX4OL TXGP1 |
tumor necrosis factor (ligand) superfamily, member 4 | Genistein results in decreased expression of TNFSF4 mRNA |
decreases expression
|
mRNA |
18444173
|
| D019833 | 8744 |
TNFSF9
4-1BB-L CD137L |
tumor necrosis factor (ligand) superfamily, member 9 | Genistein results in increased expression of TNFSF9 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 85456 |
TNKS1BP1
TAB182 |
tankyrase 1 binding protein 1, 182kDa | ESR2 promotes the reaction [Genistein results in decreased expression of TNKS1BP1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 85456 |
TNKS1BP1
TAB182 |
tankyrase 1 binding protein 1, 182kDa | Genistein results in decreased expression of TNKS1BP1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 7138 |
TNNT1
ANM NEM5 STNT TNT TNTS |
troponin T type 1 (skeletal, slow) | Genistein results in decreased expression of TNNT1 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 10452 |
TOMM40
C19orf1 D19S1177E PER-EC1 PEREC1 TOM40 |
translocase of outer mitochondrial membrane 40 homolog (yeast) | ESR1 promotes the reaction [Genistein results in decreased expression of TOMM40 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 10452 |
TOMM40
C19orf1 D19S1177E PER-EC1 PEREC1 TOM40 |
translocase of outer mitochondrial membrane 40 homolog (yeast) | Genistein results in decreased expression of TOMM40 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 7153 |
TOP2A
TOP2 TP2A |
topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) | Genistein results in increased expression of TOP2A mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 7155 |
TOP2B
TOPIIB top2beta |
topoisomerase (DNA) II beta 180kDa (EC:5.99.1.3) | ESR2 promotes the reaction [Genistein results in decreased expression of TOP2B protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 7155 |
TOP2B
TOPIIB top2beta |
topoisomerase (DNA) II beta 180kDa (EC:5.99.1.3) | Genistein results in decreased expression of TOP2B protein |
decreases expression
|
protein |
20884965
|
| D019833 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | [Fluorouracil co-treated with Genistein] results in increased expression of TP53 mRNA |
affects cotreatment
/ increases expression |
mRNA |
15896711
|
| D019833 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | Genistein affects the expression of TP53 mRNA |
affects expression
|
mRNA |
18431742
|
| D019833 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | Genistein affects the expression of TP53 protein |
affects expression
|
protein |
18431742
|
| D019833 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | [Genistein co-treated with trichostatin A] results in increased expression of TP53 protein |
affects cotreatment
/ increases expression |
protein |
22626855
|
| D019833 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | Genistein inhibits the reaction [HIST3H3 protein modified form binds to TP53 promoter] |
affects binding
/ decreases reaction |
promoter |
18431742
|
| D019833 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | Genistein inhibits the reaction [SIRT1 protein binds to TP53 promoter] |
affects binding
/ decreases reaction |
promoter |
18431742
|
| D019833 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | Genistein promotes the reaction [Fluorouracil results in increased expression of TP53 protein] |
increases expression
/ increases reaction |
protein |
15896711
|
| D019833 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | [[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased expression of TP53 protein |
decreases activity
/ increases expression |
protein |
18431742
|
| D019833 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | Genistein results in increased expression of TP53 protein |
increases expression
|
protein |
19800779
|
| D019833 | 9537 |
TP53I11
PIG11 |
tumor protein p53 inducible protein 11 | Genistein results in decreased expression of TP53I11 mRNA |
decreases expression
|
mRNA |
15757668
|
| D019833 | 9540 |
TP53I3
PIG3 |
tumor protein p53 inducible protein 3 | ESR2 promotes the reaction [Genistein results in increased expression of TP53I3 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 9540 |
TP53I3
PIG3 |
tumor protein p53 inducible protein 3 | Genistein results in increased expression of TP53I3 protein |
increases expression
|
protein |
20884965
|
| D019833 | 94241 |
TP53INP1
SIP TP53DINP1 TP53INP1A TP53INP1B Teap p53DINP1 |
tumor protein p53 inducible nuclear protein 1 | Genistein results in decreased expression of TP53INP1 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 94241 |
TP53INP1
SIP TP53DINP1 TP53INP1A TP53INP1B Teap p53DINP1 |
tumor protein p53 inducible nuclear protein 1 | Genistein results in increased expression of TP53INP1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 8626 |
TP63
AIS B(p51A) B(p51B) EEC3 KET LMS NBP OFC8 RHS SHFM4 TP53CP TP53L TP73L p40 p51 p53CP p63 p73H p73L |
tumor protein p63 | Genistein results in increased expression of TP63 mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 7164 |
TPD52L1
D53 hD53 |
tumor protein D52-like 1 | Genistein results in increased expression of TPD52L1 mRNA |
increases expression
|
mRNA |
15757668
|
| D019833 | 27010 |
TPK1
HTPK1 PP20 THMD5 |
thiamin pyrophosphokinase 1 (EC:2.7.6.2) | Genistein results in decreased expression of TPK1 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 7168 |
TPM1
C15orf13 CMD1Y CMH3 HTM-alpha LVNC9 TMSA |
tropomyosin 1 (alpha) | Genistein results in decreased expression of TPM1 mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 7170 |
TPM3
CAPM1 CFTD NEM1 OK/SW-cl.5 TM-5 TM3 TM30 TM30nm TM5 TPMsk3 TRK hscp30 |
tropomyosin 3 | Genistein results in increased expression of TPM3 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 7173 |
TPO
MSA TDH2A TPX |
thyroid peroxidase (EC:1.11.1.8) | Genistein results in decreased activity of TPO protein |
decreases activity
|
protein |
21809831
|
| D019833 | 7175 |
TPR
|
translocated promoter region, nuclear basket protein | ESR1 promotes the reaction [Genistein results in decreased expression of TPR protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 7175 |
TPR
|
translocated promoter region, nuclear basket protein | Genistein results in decreased expression of TPR protein |
decreases expression
|
protein |
20884965
|
| D019833 | 10626 |
TRIM16
EBBP |
tripartite motif containing 16 | Genistein results in decreased expression of TRIM16 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 7706 |
TRIM25
EFP RNF147 Z147 ZNF147 |
tripartite motif containing 25 (EC:6.3.2.19 6.3.2.n3) | Genistein results in increased expression of TRIM25 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 129868 |
TRIM43
TRIM43A |
tripartite motif containing 43 | Genistein results in decreased expression of TRIM43 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 653192 |
TRIM43B
|
tripartite motif containing 43B | Genistein results in decreased expression of TRIM43B mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 9319 |
TRIP13
16E1BP |
thyroid hormone receptor interactor 13 | Genistein results in increased expression of TRIP13 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 51504 |
TRMT112
HSPC152 HSPC170 TRM112 TRMT11-2 |
tRNA methyltransferase 11-2 homolog (S. cerevisiae) | ESR2 promotes the reaction [Genistein results in increased expression of TRMT112 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 51504 |
TRMT112
HSPC152 HSPC170 TRM112 TRMT11-2 |
tRNA methyltransferase 11-2 homolog (S. cerevisiae) | Genistein results in increased expression of TRMT112 protein |
increases expression
|
protein |
20884965
|
| D019833 | 8848 |
TSC22D1
Ptg-2 TGFB1I4 TSC22 |
TSC22 domain family, member 1 | Genistein results in decreased expression of TSC22D1 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 8848 |
TSC22D1
Ptg-2 TGFB1I4 TSC22 |
TSC22 domain family, member 1 | Genistein results in increased expression of TSC22D1 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 25987 |
TSKU
E2IG4 LRRC54 TSK |
tsukushi, small leucine rich proteoglycan | Genistein results in increased expression of TSKU mRNA |
increases expression
|
mRNA |
19371625
23019147 |
| D019833 | 23554 |
TSPAN12
EVR5 NET-2 NET2 TM4SF12 |
tetraspanin 12 | Genistein results in decreased expression of TSPAN12 mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 146057 |
TTBK2
SCA11 TTBK |
tau tubulin kinase 2 (EC:2.7.11.1) | ESR1 promotes the reaction [Genistein results in increased expression of TTBK2 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 146057 |
TTBK2
SCA11 TTBK |
tau tubulin kinase 2 (EC:2.7.11.1) | Genistein results in increased expression of TTBK2 protein |
increases expression
|
protein |
20884965
|
| D019833 | 283237 |
TTC9C
|
tetratricopeptide repeat domain 9C | ESR2 promotes the reaction [Genistein results in decreased expression of TTC9C protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 283237 |
TTC9C
|
tetratricopeptide repeat domain 9C | Genistein results in decreased expression of TTC9C protein |
decreases expression
|
protein |
20884965
|
| D019833 | 7272 |
TTK
CT96 ESK MPH1 MPS1 MPS1L1 PYT |
TTK protein kinase (EC:2.7.12.1) | Genistein affects the expression of TTK mRNA |
affects expression
|
mRNA |
18847459
|
| D019833 | 23170 |
TTLL12
dJ526I14.2 |
tubulin tyrosine ligase-like family, member 12 | Genistein results in increased expression of TTLL12 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 7277 |
TUBA4A
H2-ALPHA TUBA1 |
tubulin, alpha 4a | Genistein results in decreased expression of TUBA4A mRNA |
decreases expression
|
mRNA |
20884965
|
| D019833 | 203068 |
TUBB
M40 OK/SW-cl.56 TUBB1 TUBB5 |
tubulin, beta class I | Genistein results in decreased expression of TUBB mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 84617 |
TUBB6
HsT1601 TUBB-5 |
tubulin, beta 6 class V | Genistein results in increased expression of TUBB6 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 7289 |
TULP3
TUBL3 |
tubby like protein 3 | Genistein results in decreased expression of TULP3 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 200081 |
TXLNA
IL14 RP4-622L5.4 TXLN |
taxilin alpha | Genistein results in decreased expression of TXLNA mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 7295 |
TXN
TRDX TRX TRX1 |
thioredoxin | Genistein results in decreased expression of TXN mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 7296 |
TXNRD1
GRIM-12 TR TR1 TRXR1 TXNR |
thioredoxin reductase 1 (EC:1.8.1.9) | Genistein results in increased expression of TXNRD1 mRNA |
increases expression
|
mRNA |
18444173
|
| D019833 | 7298 |
TYMS
HST422 TMS TS |
thymidylate synthetase (EC:2.1.1.45) | Genistein results in increased expression of TYMS mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 7306 |
TYRP1
CAS2 CATB GP75 OCA3 TRP TRP1 TYRP b-PROTEIN |
tyrosinase-related protein 1 (EC:1.14.18.-) | Genistein results in decreased expression of TYRP1 mRNA |
decreases expression
|
mRNA |
20706672
|
| D019833 | 6675 |
UAP1
AGX AGX1 AGX2 SPAG2 |
UDP-N-acetylglucosamine pyrophosphorylase 1 (EC:2.7.7.23 2.7.7.83) | Genistein results in decreased expression of UAP1 mRNA |
decreases expression
|
mRNA |
15378649
|
| D019833 | 9898 |
UBAP2L
NICE-4 |
ubiquitin associated protein 2-like | Genistein results in decreased expression of UBAP2L mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 11065 |
UBE2C
UBCH10 dJ447F3.2 |
ubiquitin-conjugating enzyme E2C (EC:6.3.2.19) | Genistein affects the expression of UBE2C mRNA alternative form |
affects expression
|
mRNA |
18847459
|
| D019833 | 11065 |
UBE2C
UBCH10 dJ447F3.2 |
ubiquitin-conjugating enzyme E2C (EC:6.3.2.19) | Genistein results in increased expression of UBE2C mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 9246 |
UBE2L6
RIG-B UBCH8 |
ubiquitin-conjugating enzyme E2L 6 (EC:6.3.2.19) | ESR2 promotes the reaction [Genistein results in decreased expression of UBE2L6 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 9246 |
UBE2L6
RIG-B UBCH8 |
ubiquitin-conjugating enzyme E2L 6 (EC:6.3.2.19) | Genistein results in decreased expression of UBE2L6 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 29089 |
UBE2T
PIG50 |
ubiquitin-conjugating enzyme E2T (putative) (EC:6.3.2.19) | Genistein results in increased expression of UBE2T mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 56893 |
UBQLN4
A1U A1Up C1orf6 CIP75 UBIN |
ubiquilin 4 | Genistein results in increased expression of UBQLN4 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 7343 |
UBTF
NOR-90 UBF UBF-1 UBF1 |
upstream binding transcription factor, RNA polymerase I | ESR2 promotes the reaction [Genistein results in decreased expression of UBTF protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 7343 |
UBTF
NOR-90 UBF UBF-1 UBF1 |
upstream binding transcription factor, RNA polymerase I | Genistein results in decreased expression of UBTF protein |
decreases expression
|
protein |
20884965
|
| D019833 | 7345 |
UCHL1
NDGOA PARK5 PGP_9.5 PGP9.5 PGP95 Uch-L1 |
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (EC:3.4.19.12) | [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of UCHL1 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
16963248
|
| D019833 | 7358 |
UGDH
GDH UDP-GlcDH UDPGDH UGD |
UDP-glucose 6-dehydrogenase (EC:1.1.1.22) | ESR2 promotes the reaction [Genistein results in decreased expression of UGDH protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 7358 |
UGDH
GDH UDP-GlcDH UDPGDH UGD |
UDP-glucose 6-dehydrogenase (EC:1.1.1.22) | Genistein results in decreased expression of UGDH protein |
decreases expression
|
protein |
20884965
|
| D019833 | 7358 |
UGDH
GDH UDP-GlcDH UDPGDH UGD |
UDP-glucose 6-dehydrogenase (EC:1.1.1.22) | Genistein results in increased expression of UGDH mRNA |
increases expression
|
mRNA |
15378649
16865672 |
| D019833 | 54658 |
UGT1A1
BILIQTL1 GNT1 HUG-BR1 UDPGT UDPGT_1-1 UGT1 UGT1A |
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) | Genistein results in decreased activity of UGT1A1 protein |
decreases activity
|
protein |
16051636
|
| D019833 | 54658 |
UGT1A1
BILIQTL1 GNT1 HUG-BR1 UDPGT UDPGT_1-1 UGT1 UGT1A |
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) | Genistein results in decreased expression of UGT1A1 mRNA |
decreases expression
|
mRNA |
18634814
|
| D019833 | 54658 |
UGT1A1
BILIQTL1 GNT1 HUG-BR1 UDPGT UDPGT_1-1 UGT1 UGT1A |
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) | Genistein results in decreased expression of UGT1A1 protein |
decreases expression
|
protein |
18634814
|
| D019833 | 54658 |
UGT1A1
BILIQTL1 GNT1 HUG-BR1 UDPGT UDPGT_1-1 UGT1 UGT1A |
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) | UGT1A1 protein results in increased glucuronidation of Genistein |
increases glucuronidation
|
protein |
14557274
15988124 |
| D019833 | 54575 |
UGT1A10
UDPGT UGT-1J UGT1-10 UGT1.10 UGT1J |
UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) | UGT1A10 protein results in increased glucuronidation of Genistein |
increases glucuronidation
|
protein |
14557274
|
| D019833 | 54659 |
UGT1A3
UDPGT UDPGT_1-3 UGT-1C UGT1-03 UGT1.3 UGT1C |
UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) | Genistein results in decreased expression of UGT1A3 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 54659 |
UGT1A3
UDPGT UDPGT_1-3 UGT-1C UGT1-03 UGT1.3 UGT1C |
UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) | UGT1A3 protein results in increased glucuronidation of Genistein |
increases glucuronidation
|
protein |
15988124
|
| D019833 | 54577 |
UGT1A7
UDPGT UDPGT_1-7 UGT-1G UGT1-07 UGT1.7 UGT1G |
UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) | UGT1A7 protein results in increased glucuronidation of Genistein |
increases glucuronidation
|
protein |
14557274
|
| D019833 | 54576 |
UGT1A8
UDPGT UDPGT_1-8 UGT-1H UGT1-08 UGT1.8 UGT1A8S UGT1H |
UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) | UGT1A8 protein results in increased glucuronidation of Genistein |
increases glucuronidation
|
protein |
14557274
|
| D019833 | 54600 |
UGT1A9
HLUGP4 LUGP4 UDPGT UDPGT_1-9 UGT-1I UGT1-09 UGT1-9 UGT1.9 UGT1AI UGT1I |
UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) | UGT1A9 protein results in increased glucuronidation of Genistein |
increases glucuronidation
|
protein |
14557274
15988124 |
| D019833 | 7366 |
UGT2B15
HLUG4 UDPGT_2B8 UDPGT2B15 UDPGTH3 UGT2B8 |
UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) | Genistein results in increased expression of UGT2B15 mRNA |
increases expression
|
mRNA |
16690804
16865672 23524099 |
| D019833 | 7367 |
UGT2B17
BMND12 UDPGT2B17 |
UDP glucuronosyltransferase 2 family, polypeptide B17 (EC:2.4.1.17) | Genistein results in increased expression of UGT2B17 mRNA |
increases expression
|
mRNA |
16865672
|
| D019833 | 29128 |
UHRF1
ICBP90 Np95 RNF106 hNP95 hUHRF1 |
ubiquitin-like with PHD and ring finger domains 1 (EC:6.3.2.19) | Genistein results in increased expression of UHRF1 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 7374 |
UNG
DGU HIGM4 HIGM5 UDG UNG1 UNG15 UNG2 |
uracil-DNA glycosylase (EC:3.2.2.27) | Genistein results in increased expression of UNG mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 10868 |
USP20
LSFR3A VDU2 hVDU2 |
ubiquitin specific peptidase 20 (EC:3.4.19.12) | Genistein results in decreased expression of USP20 mRNA |
decreases expression
|
mRNA |
16705744
|
| D019833 | 114990 |
VASN
SLITL2 |
vasorin | Genistein results in increased expression of VASN mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 10493 |
VAT1
VATI |
vesicle amine transport 1 | ESR1 promotes the reaction [Genistein results in decreased expression of VAT1 protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 10493 |
VAT1
VATI |
vesicle amine transport 1 | Genistein results in decreased expression of VAT1 protein |
decreases expression
|
protein |
20884965
|
| D019833 | 7409 |
VAV1
VAV |
vav 1 guanine nucleotide exchange factor | Genistein inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of VAV1 protein] |
decreases reaction
/ increases phosphorylation |
protein |
20561557
|
| D019833 | 7412 |
VCAM1
CD106 INCAM-100 |
vascular cell adhesion molecule 1 | ESR2 gene polymorphism affects the reaction [[Genistein co-treated with daidzein] affects the expression of VCAM1 protein] |
affects cotreatment
/ affects expression / affects reaction |
protein |
16332659
|
| D019833 | 7412 |
VCAM1
CD106 INCAM-100 |
vascular cell adhesion molecule 1 | fulvestrant inhibits the reaction [Genistein inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]] |
decreases reaction
/ increases expression |
mRNA |
12547825
|
| D019833 | 7412 |
VCAM1
CD106 INCAM-100 |
vascular cell adhesion molecule 1 | Genistein inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
12547825
|
| D019833 | 7414 |
VCL
CMD1W CMH15 MV MVCL |
vinculin | ESR2 promotes the reaction [Genistein results in decreased expression of VCL protein] |
decreases expression
/ increases reaction |
protein |
20884965
|
| D019833 | 7414 |
VCL
CMD1W CMH15 MV MVCL |
vinculin | Genistein results in decreased expression of VCL protein |
decreases expression
|
protein |
20884965
|
| D019833 | 79609 |
VCPKMT
C14orf138 METTL21D VCP-KMT |
valosin containing protein lysine (K) methyltransferase | Genistein results in decreased expression of VCPKMT mRNA |
decreases expression
|
mRNA |
19371625
|
| D019833 | 7421 |
VDR
NR1I1 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | fulvestrant inhibits the reaction [Genistein results in increased expression of VDR protein] |
decreases reaction
/ increases expression |
protein |
17088408
|
| D019833 | 7421 |
VDR
NR1I1 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | Genistein promotes the reaction [Calcitriol results in increased expression of VDR mRNA] |
increases expression
/ increases reaction |
mRNA |
15955619
|
| D019833 | 7421 |
VDR
NR1I1 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | Genistein promotes the reaction [Calcitriol results in increased expression of VDR protein] |
increases expression
/ increases reaction |
protein |
15955619
|
| D019833 | 7421 |
VDR
NR1I1 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | Genistein promotes the reaction [SP1 protein binds to VDR promoter] |
affects binding
/ increases reaction |
promoter |
17088408
|
| D019833 | 7421 |
VDR
NR1I1 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | Genistein results in increased expression of VDR mRNA |
increases expression
|
mRNA |
12710998
17088408 |
| D019833 | 7421 |
VDR
NR1I1 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | Genistein results in increased expression of VDR protein |
increases expression
|
protein |
12710998
17088408 |
| D019833 | 7421 |
VDR
NR1I1 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | Tamoxifen inhibits the reaction [Genistein results in increased expression of VDR mRNA] |
decreases reaction
/ increases expression |
mRNA |
12710998
|
| D019833 | 7421 |
VDR
NR1I1 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | U 0126 inhibits the reaction [Genistein results in increased expression of VDR protein] |
decreases reaction
/ increases expression |
protein |
17088408
|
| D019833 | 7422 |
VEGFA
MVCD1 VEGF VPF |
vascular endothelial growth factor A | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased secretion of VEGFA protein] |
decreases reaction
/ increases secretion |
protein |
18252963
|
| D019833 | 7422 |
VEGFA
MVCD1 VEGF VPF |
vascular endothelial growth factor A | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased secretion of VEGFA protein] |
decreases reaction
/ increases secretion |
protein |
18252963
|
| D019833 | 7422 |
VEGFA
MVCD1 VEGF VPF |
vascular endothelial growth factor A | fulvestrant inhibits the reaction [Genistein results in increased secretion of VEGFA protein] |
decreases reaction
/ increases secretion |
protein |
18252963
|
| D019833 | 7422 |
VEGFA
MVCD1 VEGF VPF |
vascular endothelial growth factor A | [Genistein co-treated with arsenic trioxide] results in decreased expression of VEGFA protein |
affects cotreatment
/ decreases expression |
protein |
21078540
|
| D019833 | 7422 |
VEGFA
MVCD1 VEGF VPF |
vascular endothelial growth factor A | Genistein results in decreased expression of VEGFA mRNA |
decreases expression
|
mRNA |
19005980
|
| D019833 | 7422 |
VEGFA
MVCD1 VEGF VPF |
vascular endothelial growth factor A | Genistein results in decreased expression of VEGFA protein |
decreases expression
|
protein |
19005980
21078540 |
| D019833 | 7422 |
VEGFA
MVCD1 VEGF VPF |
vascular endothelial growth factor A | Genistein results in increased secretion of VEGFA protein |
increases secretion
|
protein |
18252963
|
| D019833 | 7422 |
VEGFA
MVCD1 VEGF VPF |
vascular endothelial growth factor A | SB 203580 inhibits the reaction [Genistein results in increased secretion of VEGFA protein] |
decreases reaction
/ increases secretion |
protein |
18252963
|
| D019833 | 7422 |
VEGFA
MVCD1 VEGF VPF |
vascular endothelial growth factor A | wortmannin inhibits the reaction [Genistein results in increased secretion of VEGFA protein] |
decreases reaction
/ increases secretion |
protein |
18252963
|
| D019833 | 40542 | ESR2 promotes the reaction [Genistein results in increased expression of VPS24 protein] |
increases expression
/ increases reaction |
protein |
20884965
|
||
| D019833 | 40542 | Genistein results in increased expression of VPS24 protein |
increases expression
|
protein |
20884965
|
||
| D019833 | 7453 |
WARS
GAMMA-2 IFI53 IFP53 |
tryptophanyl-tRNA synthetase (EC:6.1.1.2) | Genistein results in increased expression of WARS mRNA |
increases expression
|
mRNA |
15159206
15757668 |
| D019833 | 10885 |
WDR3
DIP2 UTP12 |
WD repeat domain 3 | Genistein results in increased expression of WDR3 mRNA |
increases expression
|
mRNA |
23019147
|
| D019833 | 10785 |
WDR4
TRM82 TRMT82 |
WD repeat domain 4 | Genistein results in decreased expression of WDR4 mRNA |
decreases expression
|
mRNA |
18847459
|
| D019833 | 8839 |
WISP2
CCN5 CT58 CTGF-L |
WNT1 inducible signaling pathway protein 2 | ESR1 protein inhibits the reaction [Genistein results in increased expression of WISP2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
23384675
|
| D019833 | 8839 |
WISP2
CCN5 CT58 CTGF-L |
WNT1 inducible signaling pathway protein 2 | Genistein results in increased expression of WISP2 mRNA |
increases expression
|
mRNA |
23384675
|
| D019833 | 7476 |
WNT7A
|
wingless-type MMTV integration site family, member 7A | Genistein results in decreased expression of WNT7A mRNA |
decreases expression
|
mRNA |
16534752
|
| D019833 | 331 |
XIAP
API3 BIRC4 IAP-3 ILP1 MIHA XLP2 hIAP-3 hIAP3 |
X-linked inhibitor of apoptosis | [Genistein co-treated with TNFSF10 protein] results in decreased expression of XIAP protein |
affects cotreatment
/ decreases expression |
protein |
19497411
|
| D019833 | 331 |
XIAP
API3 BIRC4 IAP-3 ILP1 MIHA XLP2 hIAP-3 hIAP3 |
X-linked inhibitor of apoptosis | Genistein promotes the reaction [arsenic trioxide results in decreased expression of XIAP protein] |
decreases expression
/ increases reaction |
protein |
18546268
|
| D019833 | 331 |
XIAP
API3 BIRC4 IAP-3 ILP1 MIHA XLP2 hIAP-3 hIAP3 |
X-linked inhibitor of apoptosis | Genistein results in decreased expression of XIAP protein |
decreases expression
|
protein |
18546268
|
| D019833 | 51646 |
YPEL5
|
yippee-like 5 (Drosophila) | Genistein results in decreased expression of YPEL5 mRNA |
decreases expression
|
mRNA |
16474171
23019147 |
| D019833 | 79413 |
ZBED2
|
zinc finger, BED-type containing 2 | Genistein results in decreased expression of ZBED2 mRNA |
decreases expression
|
mRNA |
23019147
|
| D019833 | 84872 |
ZC3H10
ZC3HDC10 |
zinc finger CCCH-type containing 10 | Genistein results in increased expression of ZC3H10 mRNA |
increases expression
|
mRNA |
18847459
|
| D019833 | 677 |
ZFP36L1
BRF1 Berg36 ERF-1 ERF1 RNF162B TIS11B cMG1 |
ZFP36 ring finger protein-like 1 | Genistein results in decreased expression of ZFP36L1 mRNA |
decreases expression
|
mRNA |
16474171
|
| D019833 | 23414 |
ZFPM2
DIH3 FOG2 ZC2HC11B ZNF89B hFOG-2 |
zinc finger protein, FOG family member 2 | Genistein results in decreased expression of ZFPM2 mRNA |
decreases expression
|
mRNA |
15256057
|
| D019833 | 342357 |
ZKSCAN2
ZNF694 ZSCAN31 ZSCAN34 |
zinc finger with KRAB and SCAN domains 2 | Genistein results in increased expression of ZKSCAN2 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 9203 |
ZMYM3
DXS6673E MYM XFIM ZNF198L2 ZNF261 |
zinc finger, MYM-type 3 | Genistein results in increased expression of ZMYM3 mRNA |
increases expression
|
mRNA |
19371625
|
| D019833 | 7730 |
ZNF177
PIGX |
zinc finger protein 177 | Genistein results in increased expression of ZNF177 mRNA |
increases expression
|
mRNA |
15256057
|
| D019833 | 7587 |
ZNF37A
KOX21 ZNF37 |
zinc finger protein 37A | Genistein results in decreased expression of ZNF37A mRNA |
decreases expression
|
mRNA |
18444173
|
| D019833 | 80139 |
ZNF703
ZEPPO1 ZNF503L ZPO1 |
zinc finger protein 703 | Genistein results in increased expression of ZNF703 mRNA |
increases expression
|
mRNA |
16474171
|
| D019833 | 11130 |
ZWINT
HZwint-1 KNTC2AP ZWINT1 |
ZW10 interacting kinetochore protein | Genistein results in increased expression of ZWINT mRNA |
increases expression
|
mRNA |
16474171
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #610251 | Alcohol sensitivity, acute |
P05091
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P31749
P38398 |
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #114500 | Colorectal cancer; crc |
P31749
|
| #615109 | Cowden syndrome 6; cws6 |
P31749
|
| #162800 | Cyclic neutropenia |
P08246
|
| #608565 | Deafness, autosomal recessive 35; dfnb35 |
O95718
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137800 | Glioma susceptibility 1; glm1 |
P04626
P37231 |
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237450 | Hyperbilirubinemia, rotor type; hblrr |
Q9NPD5
Q9Y6L6 |
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #608232 | Leukemia, chronic myeloid; cml |
P00519
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 P04637 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #609048 | Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 |
P11802
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #254500 | Myeloma, multiple |
P24385
|
| #159900 | Myoclonic dystonia |
P14416
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
P38398 |
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #172700 | Pick disease of brain |
P10636
|
| #176920 | Proteus syndrome |
P31749
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #112100 | Yt blood group antigen |
P22303
|
| KEGG | disease name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00605 | Deafness, autosomal recessive |
O95718
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
P00519
(related)
P00519 (marker) Q03164 (related) Q03164 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
P00519
(related)
P00519 (marker) P04637 (related) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P24385 (related) P24385 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P24385 (related) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) P11802 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P11802 (related) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P24385 (related) P24385 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) P38398 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) P24385 (related) P38398 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
P24385 (related) |
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
P24385 (related) |
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P11802 (related) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
P24385 (marker) |
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H01071 | Acute alcohol sensitivity |
P05091
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00559 | von Hippel-Lindau syndrome |
P24385
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H00539 | PTEN hamartoma tumor syndrome (PHTS) |
P31749
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00192 | Xanthinuria |
P47989
(related)
Q06278 (related) |
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
Q16637 (related) |
| H00208 | Hyperbilirubinemia |
Q92887
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| MeSH disease | OMIM | compound | disease name | evidence type |
reference
pmid |
|---|---|---|---|---|---|
| D000014 | D019833 | Abnormalities, Drug-Induced |
marker/mechanism
|
20299547
|
|
| D000022 | D019833 | Abortion, Spontaneous |
marker/mechanism
|
21810550
|
|
| D000230 | D019833 | Adenocarcinoma |
marker/mechanism
therapeutic |
11389053
11473722 |
|
| C538231 | D019833 | Adenocarcinoma of lung |
therapeutic
|
22626855
|
|
| D001836 | D019833 | Body Weight Changes |
marker/mechanism
|
14580783
|
|
| D001943 | D019833 | Breast Neoplasms |
marker/mechanism
therapeutic |
16541309
16873071 17200150 |
|
| D006528 | D019833 | Carcinoma, Hepatocellular |
therapeutic
|
16924424
21078540 |
|
| D002318 | D019833 | Cardiovascular Diseases |
therapeutic
|
16332659
|
|
| D003110 | D019833 | Colonic Neoplasms |
therapeutic
|
17182828
|
|
| D000013 | D019833 | Congenital Abnormalities |
therapeutic
|
22736253
|
|
| D003924 | D019833 | Diabetes Mellitus, Type 2 |
therapeutic
|
16647724
|
|
| D012734 | D019833 | Disorders of Sex Development |
marker/mechanism
|
19672408
|
|
| D004487 | D019833 | Edema |
therapeutic
|
22981962
|
|
| D004714 | D019833 | Endometrial Hyperplasia |
therapeutic
|
16402032
|
|
| D016889 | D019833 | Endometrial Neoplasms |
therapeutic
|
11473722
|
|
| D005909 | D019833 | Glioblastoma |
therapeutic
|
16598420
|
|
| D006402 | D019833 | Hematologic Diseases |
marker/mechanism
|
21048042
|
|
| D006965 | D019833 | Hyperplasia |
therapeutic
|
22981962
|
|
| D007938 | D019833 | Leukemia |
marker/mechanism
therapeutic |
17468513
18980019 |
|
| D017254 | D019833 | Leukemic Infiltration |
therapeutic
|
22981962
|
|
| D008104 | D019833 | Liver Cirrhosis, Alcoholic |
therapeutic
|
23274713
|
|
| D008106 | D019833 | Liver Cirrhosis, Experimental |
therapeutic
|
17823541
|
|
| D008325 | D019833 | Mammary Neoplasms, Experimental |
marker/mechanism
therapeutic |
12929590
14578162 |
|
| D008679 | D019833 | Metaplasia |
marker/mechanism
|
11389053
|
|
| D009203 | D019833 | Myocardial Infarction |
therapeutic
|
17141266
|
|
| D015428 | D019833 | Myocardial Reperfusion Injury |
therapeutic
|
17141266
|
|
| D009336 | D019833 | Necrosis |
marker/mechanism
|
10572627
|
|
| D009369 | D019833 | Neoplasms |
marker/mechanism
therapeutic |
20219070
21177254 |
|
| D009421 | D019833 | Nervous System Malformations |
marker/mechanism
|
16427766
20299547 |
|
| D009845 | D019833 | Oligospermia |
marker/mechanism
|
19672408
|
|
| D010024 | D019833 | Osteoporosis |
therapeutic
|
19401787
|
|
| D015663 | D019833 | OSTEOPOROSIS, POSTMENOPAUSAL |
therapeutic
|
16169203
|
|
| D010051 | D019833 | Ovarian Neoplasms |
therapeutic
|
19005980
|
|
| D047928 | D019833 | Premature Birth |
marker/mechanism
|
21816468
|
|
| D011297 | D019833 | Prenatal Exposure Delayed Effects |
marker/mechanism
|
15925024
21048042 21177254 |
|
| D011471 | D019833 | Prostatic Neoplasms |
therapeutic
|
15256057
15378649 16925846 |
|
| D013959 | D019833 | Thyroid Diseases |
marker/mechanism
|
21800831
|
|
| D014594 | D019833 | Uterine Neoplasms |
marker/mechanism
|
11389053
|