KNApSAcK Metabolite C00026128
Metabolite
KNApSAcK Entry
| id | C00026128 |
|---|---|
| Name | Demethyleneberberine |
| CAS RN | 25459-91-0 |
| Standard InChI | InChI=1S/C19H17NO4/c1-23-18-4-3-11-7-15-13-9-17(22)16(21)8-12(13)5-6-20(15)10-14(11)19(18)24-2/h3-4,7-10,22H,5-6H2,1-2H3/p+1 |
| Standard InChI (Main Layer) | InChI=1S/C19H17NO4/c1-23-18-4-3-11-7-15-13-9-17(22)16(21)8-12(13)5-6-20(15)10-14(11)19(18)24-2/h3-4,7-10,22H,5-6H2,1-2H3 |
Cluster
| Phytochemical cluster | No. 4 |
|---|---|
| KCF-S cluster | No. 155 |
Link
ChEMBL
| By standard InChI | CHEMBL379449 |
|---|---|
| By standard InChI Main Layer | CHEMBL379449 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | C477155 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| eudicotyledons | 1 |
Family
| family name | count |
|---|---|
| Ranunculaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Thalictrum javanicum Blume B | 46968 | Ranunculaceae | eudicotyledons | Viridiplantae |
Human Protein / Gene in interaction
2 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q14654 | ATP-sensitive inward rectifier potassium channel 11 | K | CHEMBL379449 |
CHEMBL868377
(1)
|
3 / 4 |
| Q09428 | ATP-binding cassette sub-family C member 8 | K | CHEMBL379449 |
CHEMBL868377
(1)
|
5 / 3 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (7)
| OMIM | preferred title | UniProt |
|---|---|---|
| #606176 | Diabetes mellitus, permanent neonatal; pndm |
Q09428
Q14654 |
| #610374 | Diabetes mellitus, transient neonatal, 2 |
Q09428
|
| #610582 | Diabetes mellitus, transient neonatal, 3 |
Q14654
|
| #256450 | Hyperinsulinemic hypoglycemia, familial, 1; hhf1 |
Q09428
|
| #601820 | Hyperinsulinemic hypoglycemia, familial, 2; hhf2 |
Q14654
|
| #602485 | Hyperinsulinemic hypoglycemia, familial, 3; hhf3 |
Q09428
|
| #240800 | Hypoglycemia, leucine-induced; lih |
Q09428
|
KEGG DISEASE (4)
| KEGG | disease name | UniProt |
|---|---|---|
| H00512 | Permanent neonatal diabetes mellitus (PNDM) |
Q09428
(related)
Q14654 (related) |
| H00513 | Transient neonatal diabetes mellitus (TNDM) |
Q09428
(related)
Q14654 (related) |
| H01267 | Familial hyperinsulinemic hypoglycemia (HHF) |
Q09428
(related)
Q14654 (related) |
| H00409 | Type II diabetes mellitus |
Q14654
(related)
|