Metabolite

KNApSAcK Entry

id C00028075
Name Colchicone
CAS RN 1850-57-3
Standard InChI InChI=1S/C20H20O6/c1-23-16-8-6-12-13(10-15(16)22)14(21)7-5-11-9-17(24-2)19(25-3)20(26-4)18(11)12/h6,8-10H,5,7H2,1-4H3
Standard InChI (Main Layer) InChI=1S/C20H20O6/c1-23-16-8-6-12-13(10-15(16)22)14(21)7-5-11-9-17(24-2)19(25-3)20(26-4)18(11)12/h6,8-10H,5,7H2,1-4H3

Cluster

Phytochemical cluster No. 4
KCF-S cluster No. 598

Link

ChEMBL

By standard InChI CHEMBL89479
By standard InChI Main Layer CHEMBL89479

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
Liliopsida 1

Family

family name count
Colchicaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Colchicum ritchii 1094113 Colchicaceae Liliopsida Viridiplantae

Human Protein / Gene in interaction

15 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q13748 Tubulin alpha-3C/D chain Structural CHEMBL89479 CHEMBL820637 (1)
0 / 0
P68366 Tubulin alpha-4A chain Structural CHEMBL89479 CHEMBL820637 (1)
0 / 0
Q9H4B7 Tubulin beta-1 chain Structural CHEMBL89479 CHEMBL820637 (1)
1 / 0
P04350 Tubulin beta-4A chain Structural CHEMBL89479 CHEMBL820637 (1)
2 / 0
Q3ZCM7 Tubulin beta-8 chain Structural CHEMBL89479 CHEMBL820637 (1)
0 / 0
P07437 Tubulin beta chain Structural CHEMBL89479 CHEMBL820637 (1)
0 / 0
Q71U36 Tubulin alpha-1A chain Structural CHEMBL89479 CHEMBL820637 (1)
1 / 1
P68371 Tubulin beta-4B chain Structural CHEMBL89479 CHEMBL820637 (1)
0 / 0
Q13509 Tubulin beta-3 chain Structural CHEMBL89479 CHEMBL820637 (1)
2 / 1
P68363 Tubulin alpha-1B chain Unclassified protein CHEMBL89479 CHEMBL820637 (1)
0 / 0
Q13885 Tubulin beta-2A chain Structural CHEMBL89479 CHEMBL820637 (1)
0 / 0
Q6PEY2 Tubulin alpha-3E chain Unclassified protein CHEMBL89479 CHEMBL820637 (1)
0 / 0
Q9BQE3 Tubulin alpha-1C chain Unclassified protein CHEMBL89479 CHEMBL820637 (1)
0 / 0
Q9BUF5 Tubulin beta-6 chain Structural CHEMBL89479 CHEMBL820637 (1)
0 / 0
Q9BVA1 Tubulin beta-2B chain Structural CHEMBL89479 CHEMBL820637 (1)
1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#614039 Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 Q13509
#128101 Dystonia 4, torsion, autosomal dominant; dyt4 P04350
#600638 Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a Q13509
#612438 Leukodystrophy, hypomyelinating, 6; hld6 P04350
#611603 Lissencephaly 3; lis3 Q71U36
#613112 Macrothrombocytopenia, autosomal dominant, tubb1-related Q9H4B7
#610031 Polymicrogyria, symmetric or asymmetric; pmgysa Q9BVA1

KEGG DISEASE (2)

KEGG disease name UniProt
H00838 Congenital fibrosis of the extraocular muscles (CFEOM) Q13509 (related)
H00268 Lissencephaly (LIS) Q71U36 (related)