PCIDB

KNApSAcK Metabolite C00028862

Index

Metabolite

Species

Human Protein
/ Gene in interactions

Related Diseases

Metabolite

KNApSAcK Entry

id	C00028862
Name	Bisprasin / Psammaplin A
CAS RN	110659-91-1
Standard InChI	InChI=1S/C22H24Br2N4O6S2/c23-15-9-13(1-3-19(15)29)11-17(27-33)21(31)25-5-7-35-36-8-6-26-22(32)18(28-34)12-14-2-4-20(30)16(24)10-14/h1-4,9-10,29-30,33-34H,5-8,11-12H2,(H,25,31)(H,26,32)/b27-17-,28-18+
Standard InChI (Main Layer)	InChI=1S/C22H24Br2N4O6S2/c23-15-9-13(1-3-19(15)29)11-17(27-33)21(31)25-5-7-35-36-8-6-26-22(32)18(28-34)12-14-2-4-20(30)16(24)10-14/h1-4,9-10,29-30,33-34H,5-8,11-12H2,(H,25,31)(H,26,32)

Cluster

Phytochemical cluster
KCF-S cluster	No. 4998

Link

ChEMBL

By standard InChI
By standard InChI Main Layer	CHEMBL83747

KEGG

By LinkDB

CTD

By CAS RN	C098378

Species

Summary

Plant class

class name	count

Family

family name	count
Aplysinellidae	1
Pseudoceratinidae	1

List (4)

* NCBI

KNApSAcK organism	*ID	*family	*plant class	*kingdom
Aplysinella rhax	375147	Aplysinellidae		Metazoa
Psammaplysilla sp.
Pseudoceratina purpurea	1162763	Pseudoceratinidae		Metazoa
Tribullus terrestris

Human Protein / Gene in interaction

15 ChEMBL Protein in interactions

accession	description	class description	compound	assay ID (# of activities)	# of diseases (OMIM / KEGG)
Q14376	UDP-glucose 4-epimerase	Enzyme	CHEMBL83747	CHEMBL911909 (1)	1 / 1
Q13547	Histone deacetylase 1	Hydrolase	CHEMBL83747	CHEMBL697248 (1) CHEMBL1819861 (1) CHEMBL2050420 (1) CHEMBL2050434 (1)	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	CHEMBL83747	CHEMBL968346 (1) CHEMBL971110 (1) CHEMBL971112 (1)	5 / 3
P26358	DNA (cytosine-5)-methyltransferase 1	Transferase	CHEMBL83747	CHEMBL2050426 (1) CHEMBL2050446 (1)	2 / 0
Q96EB6	NAD-dependent protein deacetylase sirtuin-1	Enzyme	CHEMBL83747	CHEMBL1819959 (1)	0 / 0
Q9UBN7	Histone deacetylase 6	Hydrolase	CHEMBL83747	CHEMBL697248 (1) CHEMBL2050419 (1) CHEMBL2050440 (1) CHEMBL2188386 (1)	0 / 0
Q9BY41	Histone deacetylase 8	Hydrolase	CHEMBL83747	CHEMBL697248 (1)	2 / 0
Q969S8	Histone deacetylase 10	Hydrolase	CHEMBL83747	CHEMBL697248 (1)	0 / 0
O15379	Histone deacetylase 3	Hydrolase	CHEMBL83747	CHEMBL697248 (1)	0 / 0
P56524	Histone deacetylase 4	Hydrolase	CHEMBL83747	CHEMBL697248 (1)	1 / 1
Q8WUI4	Histone deacetylase 7	Hydrolase	CHEMBL83747	CHEMBL697248 (1)	0 / 0
Q9UQL6	Histone deacetylase 5	Hydrolase	CHEMBL83747	CHEMBL697248 (1)	0 / 0
Q9UKV0	Histone deacetylase 9	Hydrolase	CHEMBL83747	CHEMBL697248 (1)	0 / 0
Q92769	Histone deacetylase 2	Hydrolase	CHEMBL83747	CHEMBL697248 (1)	0 / 0
Q96DB2	Histone deacetylase 11	Hydrolase	CHEMBL83747	CHEMBL697248 (1)	0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM	preferred title	UniProt
%606641	Body mass index; bmi	P37231
#600430	Brachydactyly-mental retardation syndrome; bdmr	P56524
#609338	Carotid intimal medial thickness 1	P37231
#604121	Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant; adcadn	P26358
#300882	Cornelia de lange syndrome 5; cdls5	Q9BY41
#230350	Galactose epimerase deficiency	Q14376
#137800	Glioma susceptibility 1; glm1	P37231
#604367	Lipodystrophy, familial partial, type 3; fpld3	P37231
#614116	Neuropathy, hereditary sensory, type ie; hsn1e	P26358
#601665	Obesity	P37231
#309585	Wilson-turner x-linked mental retardation syndrome; wts	Q9BY41

KEGG DISEASE (5)

KEGG	disease name	UniProt
H00032	Thyroid cancer	P37231 (related)
H00409	Type II diabetes mellitus	P37231 (related)
H00420	Familial partial lipodystrophy (FPL)	P37231 (related)
H00561	Brachydacytly-mental retardation syndrome and Smith-Magenis syndrome	P56524 (related)
H00070	Galactosemia	Q14376 (related)