PCIDB

KNApSAcK Metabolite C00032697

Metabolite

KNApSAcK Entry

id C00032697
Name Actein / (-)-Actein
CAS RN 18642-44-9
Standard InChI InChI=1S/C37H56O11/c1-17-12-37(29-34(7,47-29)30(42)48-37)46-20-13-32(5)22-9-8-21-31(3,4)23(45-28-27(41)26(40)19(39)15-43-28)10-11-35(21)16-36(22,35)14-24(44-18(2)38)33(32,6)25(17)20/h17,19-30,39-42H,8-16H2,1-7H3/t17-,19-,20+,21+,22+,23+,24-,25+,26+,27-,28+,29-,30+,32+,33-,34+,35-,36+,37-/m1/s1
Standard InChI (Main Layer) InChI=1S/C37H56O11/c1-17-12-37(29-34(7,47-29)30(42)48-37)46-20-13-32(5)22-9-8-21-31(3,4)23(45-28-27(41)26(40)19(39)15-43-28)10-11-35(21)16-36(22,35)14-24(44-18(2)38)33(32,6)25(17)20/h17,19-30,39-42H,8-16H2,1-7H3

Cluster

Phytochemical cluster No. 51
KCF-S cluster No. 82

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL27958 CHEMBL1651281

KEGG

By LinkDB

CTD

By CAS RN C096064

Human Protein / Gene in interaction

CTD interaction (4)

compound gene gene name gene description interaction interaction type form reference
pmid
C096064 595 CCND1
BCL1
D11S287E
PRAD1
U21B31
cyclin D1 actein results in decreased expression of CCND1 protein decreases expression
protein 14758092
C096064 1019 CDK4
CMM3
PSK-J3
cyclin-dependent kinase 4 (EC:2.7.11.22) actein results in decreased expression of CDK4 protein decreases expression
protein 14758092
C096064 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) actein results in increased expression of CDKN1A protein increases expression
protein 14758092
C096064 5925 RB1
OSRC
RB
p105-Rb
pRb
pp110
retinoblastoma 1 actein results in decreased expression of RB1 protein decreases expression
protein 14758092