PCIDB

KNApSAcK Metabolite C00003333

Metabolite

KNApSAcK Entry

id C00003333
Name Molephantin
CAS RN 50656-66-1
Standard InChI InChI=1S/C19H22O6/c1-9(2)18(22)24-14-7-10(3)6-13(20)8-11(4)16(21)17-15(14)12(5)19(23)25-17/h6,8,14-17,21H,1,5,7H2,2-4H3/b10-6+,11-8-/t14-,15+,16-,17-/m0/s1
Standard InChI (Main Layer) InChI=1S/C19H22O6/c1-9(2)18(22)24-14-7-10(3)6-13(20)8-11(4)16(21)17-15(14)12(5)19(23)25-17/h6,8,14-17,21H,1,5,7H2,2-4H3

Cluster

Phytochemical cluster No. 38
KCF-S cluster No. 1409

Link

ChEMBL

By standard InChI CHEMBL359987
By standard InChI Main Layer CHEMBL359987 CHEMBL2002162

KEGG

By LinkDB C09512

CTD

By CAS RN C026746

Species

Summary

Plant class

class name count
asterids 2

Family

family name count
Asteraceae 2

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Elephantopus molis 318056 Asteraceae asterids Viridiplantae
Elephantopus mollis 318057 Asteraceae asterids Viridiplantae

Human Protein / Gene in interaction

28 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein CHEMBL2002162 CHEMBL2114784 (1)
1 / 1
P14618 Pyruvate kinase PKM Enzyme CHEMBL2002162 CHEMBL1613996 (1) CHEMBL1614428 (1)
0 / 0
P06746 DNA polymerase beta Enzyme CHEMBL2002162 CHEMBL1614079 (1)
0 / 0
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily CHEMBL2002162 CHEMBL1614153 (1)
1 / 4
P11473 Vitamin D3 receptor NR1I1 CHEMBL2002162 CHEMBL1794311 (1)
2 / 3
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL2002162 CHEMBL1738606 (1)
0 / 0
P42858 Huntingtin Unclassified protein CHEMBL2002162 CHEMBL1613918 (1)
1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL2002162 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL2002162 CHEMBL2114843 (1) CHEMBL2114780 (1)
0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein CHEMBL2002162 CHEMBL1613838 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL2002162 CHEMBL2114788 (1)
0 / 0
Q04206 Transcription factor p65 Transcription Factor CHEMBL359987 CHEMBL828644 (1) CHEMBL835063 (1)
CHEMBL861583 (1)
0 / 0
Q9Y253 DNA polymerase eta Enzyme CHEMBL2002162 CHEMBL1794569 (1)
1 / 1
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme CHEMBL2002162 CHEMBL1963863 (1)
0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein CHEMBL2002162 CHEMBL1614342 (1)
1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL2002162 CHEMBL1738588 (1) CHEMBL1738317 (1)
0 / 0
Q9UNA4 DNA polymerase iota Enzyme CHEMBL2002162 CHEMBL1794483 (1)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL2002162 CHEMBL1614211 (1)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL2002162 CHEMBL1614250 (1) CHEMBL1614421 (1)
4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL2002162 CHEMBL2114908 (1)
0 / 0
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL2002162 CHEMBL1794536 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL2002162 CHEMBL1613914 (1)
0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme CHEMBL2002162 CHEMBL1613829 (1)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL2002162 CHEMBL1738442 (1)
0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL2002162 CHEMBL1614364 (1)
1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL2002162 CHEMBL2354311 (1)
1 / 0
Q00653 Nuclear factor NF-kappa-B p100 subunit Transcription Factor CHEMBL359987 CHEMBL828644 (1) CHEMBL835063 (1)
0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor CHEMBL359987 CHEMBL828644 (1) CHEMBL835063 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#208900 Ataxia-telangiectasia; at Q13315
#114500 Colorectal cancer; crc P84022
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#143100 Huntington disease; hd P42858
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#257220 Niemann-pick disease, type c1; npc1 O15118
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (14)

KEGG disease name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00005 Chronic lymphocytic leukemia (CLL) Q13315 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00094 DNA repair defects Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)