PCIDB

KNApSAcK Metabolite C00003334

Metabolite

KNApSAcK Entry

id C00003334
Name Molephantinin
CAS RN 56221-98-8
Standard InChI InChI=1S/C20H24O6/c1-6-11(3)19(23)25-15-8-10(2)7-14(21)9-12(4)17(22)18-16(15)13(5)20(24)26-18/h6-7,9,15-18,22H,5,8H2,1-4H3/b10-7+,11-6+,12-9-/t15-,16+,17-,18-/m0/s1
Standard InChI (Main Layer) InChI=1S/C20H24O6/c1-6-11(3)19(23)25-15-8-10(2)7-14(21)9-12(4)17(22)18-16(15)13(5)20(24)26-18/h6-7,9,15-18,22H,5,8H2,1-4H3

Cluster

Phytochemical cluster No. 38
KCF-S cluster No. 1409

Link

ChEMBL

By standard InChI CHEMBL189129
By standard InChI Main Layer CHEMBL189129 CHEMBL1992486

KEGG

By LinkDB C09513

CTD

By CAS RN C026747

Species

Summary

Plant class

class name count
asterids 2

Family

family name count
Asteraceae 2

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Elephantopus molis 318056 Asteraceae asterids Viridiplantae
Elephantopus mollis 318057 Asteraceae asterids Viridiplantae

Human Protein / Gene in interaction

23 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein CHEMBL1992486 CHEMBL2114784 (1)
1 / 1
P07550 Beta-2 adrenergic receptor Adrenergic receptor CHEMBL1992486 CHEMBL1738166 (1)
0 / 1
P11473 Vitamin D3 receptor NR1I1 CHEMBL1992486 CHEMBL1794311 (1)
2 / 3
P42858 Huntingtin Unclassified protein CHEMBL1992486 CHEMBL1613918 (1)
1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL1992486 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL1992486 CHEMBL2114780 (1)
0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein CHEMBL1992486 CHEMBL1613838 (1)
0 / 0
Q04206 Transcription factor p65 Transcription Factor CHEMBL189129 CHEMBL828644 (1) CHEMBL835063 (1)
CHEMBL861583 (1)
0 / 0
Q9Y253 DNA polymerase eta Enzyme CHEMBL1992486 CHEMBL1794569 (1)
1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL1992486 CHEMBL1794401 (1)
0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme CHEMBL1992486 CHEMBL1963863 (1) CHEMBL2114934 (1)
0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein CHEMBL1992486 CHEMBL1614342 (1)
1 / 1
O75030 Microphthalmia-associated transcription factor Unclassified protein CHEMBL1992486 CHEMBL1738549 (1) CHEMBL1738671 (1)
CHEMBL1737866 (1) CHEMBL1738318 (1)
4 / 5
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL1992486 CHEMBL1738588 (1)
0 / 0
Q9UNA4 DNA polymerase iota Enzyme CHEMBL1992486 CHEMBL1794483 (1)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL1992486 CHEMBL1614250 (1) CHEMBL1614421 (1)
4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL1992486 CHEMBL1738184 (1) CHEMBL2114908 (1)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL1992486 CHEMBL1738442 (1)
0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL1992486 CHEMBL2354311 (1)
1 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme CHEMBL1992486 CHEMBL2114734 (1)
0 / 0
Q00653 Nuclear factor NF-kappa-B p100 subunit Transcription Factor CHEMBL189129 CHEMBL828644 (1) CHEMBL835063 (1)
0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor CHEMBL189129 CHEMBL828644 (1) CHEMBL835063 (1)
0 / 0
Q06710 Paired box protein Pax-8 Unclassified protein CHEMBL1992486 CHEMBL2354301 (1)
1 / 2

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness O75030
#114500 Colorectal cancer; crc P84022
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#143100 Huntington disease; hd P42858
#218700 Hypothyroidism, congenital, nongoitrous, 2; chng2 Q06710
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#614456 Melanoma, cutaneous malignant, susceptibility to, 8; cmm8 O75030
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#257220 Niemann-pick disease, type c1; npc1 O15118
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#103500 Tietz syndrome O75030
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#193510 Waardenburg syndrome, type 2a; ws2a O75030
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (17)

KEGG disease name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00038 Malignant melanoma O75030 (related)
O75030 (marker)
H00169 Ocular albinism O75030 (related)
H00759 Waardenburg syndrome (WS) O75030 (related)
H01187 Tietz syndrome O75030 (related)
H00079 Asthma P07550 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00032 Thyroid cancer Q06710 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) Q06710 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)