KNApSAcK Metabolite C00003349
Metabolite
KNApSAcK Entry
| id | C00003349 |
|---|---|
| Name | Picrotin |
| CAS RN | 21416-53-5 |
| Standard InChI | InChI=1S/C15H18O7/c1-12(2,18)6-7-10(16)20-8(6)9-13(3)14(7,19)4-5-15(13,22-5)11(17)21-9/h5-9,18-19H,4H2,1-3H3/t5-,6+,7-,8-,9-,13-,14-,15+/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C15H18O7/c1-12(2,18)6-7-10(16)20-8(6)9-13(3)14(7,19)4-5-15(13,22-5)11(17)21-9/h5-9,18-19H,4H2,1-3H3 |
Cluster
| Phytochemical cluster | No. 38 |
|---|---|
| KCF-S cluster | No. 1974 |
Link
ChEMBL
| By standard InChI | CHEMBL478523 |
|---|---|
| By standard InChI Main Layer | CHEMBL478523 CHEMBL1377038 CHEMBL1881068 |
KEGG
| By LinkDB | C09528 |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| eudicotyledons | 1 |
Family
| family name | count |
|---|---|
| Menispermaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Anamirta cocculus | 432627 | Menispermaceae | eudicotyledons | Viridiplantae |
Human Protein / Gene in interaction
9 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P23415 | Glycine receptor subunit alpha-1 | GLR alpha | CHEMBL478523 |
CHEMBL1629151
(1)
|
1 / 1 |
| O75311 | Glycine receptor subunit alpha-3 | GLR alpha | CHEMBL478523 |
CHEMBL1629289
(1)
|
0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | CHEMBL1377038 |
CHEMBL1614458
(1)
|
0 / 0 |
| P23416 | Glycine receptor subunit alpha-2 | GLR alpha | CHEMBL478523 |
CHEMBL1629261
(1)
|
0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | CHEMBL1881068 |
CHEMBL1794401
(1)
|
0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL1377038 |
CHEMBL1614108
(1)
CHEMBL1613886
(1)
|
0 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | CHEMBL1377038 |
CHEMBL1613914
(1)
|
0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | CHEMBL1377038 |
CHEMBL1613933
(1)
|
0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | CHEMBL1377038 |
CHEMBL1613933
(1)
|
1 / 6 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (2)
| OMIM | preferred title | UniProt |
|---|---|---|
| #149400 | Hyperekplexia, hereditary 1; hkpx1 |
P23415
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
KEGG DISEASE (6)
| KEGG | disease name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00769 | Hyperekplexia |
P23415
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|