PCIDB

KNApSAcK Metabolite C00037229

Metabolite

KNApSAcK Entry

id C00037229
Name Gummosin
CAS RN 51819-92-2
Standard InChI InChI=1S/C24H30O4/c1-15-5-9-20-23(2,3)21(25)11-12-24(20,4)18(15)14-27-17-8-6-16-7-10-22(26)28-19(16)13-17/h6-8,10,13,18,20-21,25H,1,5,9,11-12,14H2,2-4H3/t18?,20-,21+,24+/m1/s1
Standard InChI (Main Layer) InChI=1S/C24H30O4/c1-15-5-9-20-23(2,3)21(25)11-12-24(20,4)18(15)14-27-17-8-6-16-7-10-22(26)28-19(16)13-17/h6-8,10,13,18,20-21,25H,1,5,9,11-12,14H2,2-4H3

Cluster

Phytochemical cluster
KCF-S cluster No. 209

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL178485 CHEMBL1078138 CHEMBL1326960 CHEMBL1507262 CHEMBL2000585

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
asterids 1

Family

family name count
Apiaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Ferula assa-foetida 52471 Apiaceae asterids Viridiplantae

Human Protein / Gene in interaction

13 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL1507262 CHEMBL1738312 (1)
0 / 0
Q99700 Ataxin-2 Unclassified protein CHEMBL1507262 CHEMBL2114784 (1)
1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL1507262 CHEMBL1794585 (1)
0 / 0
P37840 Alpha-synuclein Unclassified protein CHEMBL1507262 CHEMBL2354282 (1)
4 / 2
P16473 Thyrotropin receptor Glycohormone receptor CHEMBL1326960 CHEMBL1614281 (1) CHEMBL1614361 (1)
3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL1326960 CHEMBL1614027 (1)
0 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL1507262 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL1507262 CHEMBL2114843 (1) CHEMBL2114780 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL1507262 CHEMBL2114788 (1)
0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL1326960 CHEMBL1614227 (1)
3 / 3
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL1326960 CHEMBL1613777 (1)
1 / 1
Q9UNA4 DNA polymerase iota Enzyme CHEMBL1507262 CHEMBL1794483 (1)
0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL1507262 CHEMBL1738184 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#114500 Colorectal cancer; crc P84022
#127750 Dementia, lewy body; dlb P37840
#609535 Drug metabolism, poor, cyp2c19-related P33261
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (10)

KEGG disease name UniProt
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)