PCIDB

KNApSAcK Metabolite C00038122

Metabolite

KNApSAcK Entry

id C00038122
Name 10E-Hymenialdisine
CAS RN 186819-96-5
Standard InChI InChI=1S/C11H10BrN5O2/c12-6-3-5-4(7-10(19)17-11(13)16-7)1-2-14-9(18)8(5)15-6/h3,15H,1-2H2,(H,14,18)(H3,13,16,17,19)/b7-4+
Standard InChI (Main Layer) InChI=1S/C11H10BrN5O2/c12-6-3-5-4(7-10(19)17-11(13)16-7)1-2-14-9(18)8(5)15-6/h3,15H,1-2H2,(H,14,18)(H3,13,16,17,19)

Cluster

Phytochemical cluster
KCF-S cluster No. 1755

Link

ChEMBL

By standard InChI CHEMBL359106
By standard InChI Main Layer CHEMBL359106 CHEMBL361708

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count

Family

family name count
Axinellidae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Stylissa massa 279589 Axinellidae Metazoa

Human Protein / Gene in interaction

22 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q02750 Dual specificity mitogen-activated protein kinase kinase 1 Ste7 CHEMBL359106 CHEMBL361708 CHEMBL731425 (2) CHEMBL769165 (2)
CHEMBL939218 (1)
1 / 1
P17252 Protein kinase C alpha type Alpha CHEMBL361708 CHEMBL828395 (1)
0 / 0
O14757 Serine/threonine-protein kinase Chk1 Chk1 CHEMBL361708 CHEMBL833021 (1) CHEMBL990372 (1)
0 / 0
P68400 Casein kinase II subunit alpha Ck2 CHEMBL361708 CHEMBL830869 (1)
0 / 0
O15226 NF-kappa-B-repressing factor Transcription Factor CHEMBL361708 CHEMBL882763 (1)
0 / 0
P14635 G2/mitotic-specific cyclin-B1 Other cytosolic protein CHEMBL361708 CHEMBL665968 (1) CHEMBL1249832 (1)
CHEMBL2092321 (1)
0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 CHEMBL361708 CHEMBL663595 (1)
0 / 0
P06493 Cyclin-dependent kinase 1 Cdc2 CHEMBL361708 CHEMBL665968 (1) CHEMBL1249832 (1)
CHEMBL2092321 (1)
0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 CHEMBL361708 CHEMBL2092320 (1) CHEMBL2092323 (1)
0 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family CHEMBL361708 CHEMBL663595 (1)
0 / 0
P24864 G1/S-specific cyclin-E1 Other cytosolic protein CHEMBL361708 CHEMBL2092320 (1)
0 / 2
P49841 Glycogen synthase kinase-3 beta Gsk CHEMBL361708 CHEMBL686320 (1) CHEMBL1034478 (1)
CHEMBL1249829 (1) CHEMBL2092319 (1)
0 / 0
Q99683 Mitogen-activated protein kinase kinase kinase 5 Ste11 CHEMBL361708 CHEMBL965354 (1) CHEMBL965356 (1)
0 / 0
P48730 Casein kinase I isoform delta Ck1 CHEMBL361708 CHEMBL828168 (1)
1 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL359106 CHEMBL361708 CHEMBL729502 (2) CHEMBL828116 (1)
0 / 0
P05771 Protein kinase C beta type Alpha CHEMBL361708 CHEMBL828239 (1)
0 / 0
O96017 Serine/threonine-protein kinase Chk2 Rad53 CHEMBL361708 CHEMBL833022 (1) CHEMBL2092318 (1)
4 / 1
O95067 G2/mitotic-specific cyclin-B2 Other cytosolic protein CHEMBL361708 CHEMBL665968 (1) CHEMBL1249832 (1)
0 / 0
Q8WWL7 G2/mitotic-specific cyclin-B3 Other cytosolic protein CHEMBL361708 CHEMBL665968 (1) CHEMBL1249832 (1)
0 / 0
P20248 Cyclin-A2 Other cytosolic protein CHEMBL361708 CHEMBL2092323 (1)
0 / 0
P78396 Cyclin-A1 Other cytosolic protein CHEMBL361708 CHEMBL2092323 (1)
0 / 0
P04049 RAF proto-oncogene serine/threonine-protein kinase Raf CHEMBL359106 CHEMBL361708 CHEMBL769165 (2)
2 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#615224 Advanced sleep phase syndrome, familial, 2; fasps2 P48730
#114480 Breast cancer O96017
#615279 Cardiofaciocutaneous syndrome 3; cfc3 Q02750
#611554 Leopard syndrome 2 P04049
#609265 Li-fraumeni syndrome 2; lfs2 O96017
#611553 Noonan syndrome 5; ns5 P04049
#259500 Osteogenic sarcoma O96017
#176807 Prostate cancer O96017

KEGG DISEASE (4)

KEGG disease name UniProt
H00881 Li-Fraumeni syndrome O96017 (related)
H00018 Gastric cancer P24864 (related)
H00055 Laryngeal cancer P24864 (related)
H00523 Noonan syndrome and related disorders Q02750 (related)