KNApSAcK Metabolite C00042143
Metabolite
KNApSAcK Entry
| id | C00042143 |
|---|---|
| Name | 4-Methyl-2-pyridinamine |
| CAS RN | 695-34-1 |
| Standard InChI | InChI=1S/C6H8N2/c1-5-2-3-8-6(7)4-5/h2-4H,1H3,(H2,7,8) |
| Standard InChI (Main Layer) | InChI=1S/C6H8N2/c1-5-2-3-8-6(7)4-5/h2-4H,1H3,(H2,7,8) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 6115 |
Link
ChEMBL
| By standard InChI | CHEMBL40833 |
|---|---|
| By standard InChI Main Layer | CHEMBL40833 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | C015672 |
|---|
Species
Summary
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Acacia rigidula Benth. | 205076 | Fabaceae | rosids | Viridiplantae |
Human Protein / Gene in interaction
11 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P29475 | Nitric oxide synthase, brain | Enzyme | CHEMBL40833 |
CHEMBL750652
(1)
CHEMBL750654
(1)
CHEMBL751656 (1) CHEMBL848735 (1) CHEMBL848737 (1) CHEMBL1056356 (1) CHEMBL1227494 (1) |
0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | CHEMBL40833 |
CHEMBL1741321
(1)
|
1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | CHEMBL40833 |
CHEMBL1741325
(1)
|
0 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | CHEMBL40833 |
CHEMBL1741322
(1)
|
0 / 0 |
| P29474 | Nitric oxide synthase, endothelial | Enzyme | CHEMBL40833 |
CHEMBL678359
(1)
CHEMBL676782
(1)
CHEMBL678077 (1) CHEMBL1056360 (1) CHEMBL1227493 (1) |
0 / 0 |
| P35228 | Nitric oxide synthase, inducible | Enzyme | CHEMBL40833 |
CHEMBL700506
(1)
CHEMBL700509
(1)
CHEMBL701150 (1) CHEMBL848735 (1) CHEMBL848737 (1) CHEMBL1056358 (1) CHEMBL1227492 (1) CHEMBL1629295 (1) |
1 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | CHEMBL40833 |
CHEMBL1741323
(1)
|
1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL40833 |
CHEMBL1741324
(1)
|
0 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | CHEMBL40833 |
CHEMBL1613914
(1)
|
0 / 0 |
| O00255 | Menin | Unclassified protein | CHEMBL40833 |
CHEMBL1614531
(1)
|
2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | CHEMBL40833 |
CHEMBL1614531
(1)
|
1 / 3 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (6)
| OMIM | preferred title | UniProt |
|---|---|---|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #611162 | Malaria, susceptibility to |
P35228
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
KEGG DISEASE (11)
| KEGG | disease name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00017 | Esophageal cancer |
P35228
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|