KNApSAcK Metabolite C00043907
Metabolite
KNApSAcK Entry
| id | C00043907 |
|---|---|
| Name | Scalaradial / (+)-Scalaradial |
| CAS RN | 53527-28-9 |
| Standard InChI | InChI=1S/C27H40O4/c1-17(30)31-23-14-22-25(4)12-7-11-24(2,3)20(25)10-13-26(22,5)21-9-8-18(15-28)19(16-29)27(21,23)6/h8,15-16,19-23H,7,9-14H2,1-6H3/t19-,20-,21-,22+,23-,25-,26-,27+/m0/s1 |
| Standard InChI (Main Layer) | InChI=1S/C27H40O4/c1-17(30)31-23-14-22-25(4)12-7-11-24(2,3)20(25)10-13-26(22,5)21-9-8-18(15-28)19(16-29)27(21,23)6/h8,15-16,19-23H,7,9-14H2,1-6H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 140 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer | CHEMBL292645 CHEMBL1078355 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | C071197 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Chromodorididae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Glossodoris rufomarginata | 508147 | Chromodorididae | Metazoa |
Human Protein / Gene in interaction
1 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P14555 | Phospholipase A2, membrane associated | Enzyme | CHEMBL292645 |
CHEMBL767138
(1)
|
0 / 0 |
CTD interaction (8)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C071197 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | scalaradial inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] |
decreases reaction
/ increases expression |
protein |
7575673
|
| C071197 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | scalaradial inhibits the reaction [IL1B protein results in increased expression of TNF protein] |
decreases reaction
/ increases expression |
protein |
7575673
|
| C071197 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] |
decreases reaction
/ increases expression |
protein |
7575673
|
| C071197 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | scalaradial inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] |
decreases reaction
/ increases expression |
protein |
7575673
|
| C071197 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] |
decreases reaction
/ increases activity / increases expression |
protein |
7575673
|
| C071197 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | scalaradial inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone] |
decreases reaction
/ increases activity / increases chemical synthesis / increases expression |
protein |
7575673
|
| C071197 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | scalaradial inhibits the reaction [IL1B protein results in increased expression of TNF protein] |
decreases reaction
/ increases expression |
protein |
7575673
|
| C071197 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] |
decreases reaction
/ increases expression |
protein |
7575673
|