KNApSAcK Metabolite C00045481
Metabolite
KNApSAcK Entry
| id | C00045481 |
|---|---|
| Name | (+)-Xestospongin B |
| CAS RN | 88840-01-1 |
| Standard InChI | InChI=1S/C29H52N2O3/c1-23-22-31-19-10-13-24-12-6-2-3-7-14-25-16-21-30-20-11-18-29(32,28(30)33-25)17-9-5-4-8-15-26(23)34-27(24)31/h23-28,32H,2-22H2,1H3 |
| Standard InChI (Main Layer) | InChI=1S/C29H52N2O3/c1-23-22-31-19-10-13-24-12-6-2-3-7-14-25-16-21-30-20-11-18-29(32,28(30)33-25)17-9-5-4-8-15-26(23)34-27(24)31/h23-28,32H,2-22H2,1H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 7547 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer | CHEMBL516249 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | C078549 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Petrosiidae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Xestospongia exigua | 595373 | Petrosiidae | Metazoa |
Human Protein / Gene in interaction
CTD interaction (8)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C078549 | 596 |
BCL2
Bcl-2 PPP1R50 |
B-cell CLL/lymphoma 2 | BCL2 mutant form promotes the reaction [xestospongin B inhibits the reaction [ITPR1 protein binds to BECN1 protein]] |
affects binding
/ decreases reaction / increases reaction |
mutant form |
19325567
|
| C078549 | 596 |
BCL2
Bcl-2 PPP1R50 |
B-cell CLL/lymphoma 2 | BCL2 protein inhibits the reaction [xestospongin B inhibits the reaction [ITPR1 protein binds to BECN1 protein]] |
affects binding
/ decreases reaction |
protein |
19325567
|
| C078549 | 8678 |
BECN1
ATG6 VPS30 beclin1 |
beclin 1, autophagy related | BCL2 mutant form promotes the reaction [xestospongin B inhibits the reaction [ITPR1 protein binds to BECN1 protein]] |
affects binding
/ decreases reaction / increases reaction |
protein |
19325567
|
| C078549 | 8678 |
BECN1
ATG6 VPS30 beclin1 |
beclin 1, autophagy related | BCL2 protein inhibits the reaction [xestospongin B inhibits the reaction [ITPR1 protein binds to BECN1 protein]] |
affects binding
/ decreases reaction |
protein |
19325567
|
| C078549 | 8678 |
BECN1
ATG6 VPS30 beclin1 |
beclin 1, autophagy related | xestospongin B inhibits the reaction [ITPR1 protein binds to BECN1 protein] |
affects binding
/ decreases reaction |
protein |
19325567
|
| C078549 | 3708 |
ITPR1
INSP3R1 IP3R IP3R1 SCA15 SCA16 SCA29 |
inositol 1,4,5-trisphosphate receptor, type 1 | BCL2 mutant form promotes the reaction [xestospongin B inhibits the reaction [ITPR1 protein binds to BECN1 protein]] |
affects binding
/ decreases reaction / increases reaction |
protein |
19325567
|
| C078549 | 3708 |
ITPR1
INSP3R1 IP3R IP3R1 SCA15 SCA16 SCA29 |
inositol 1,4,5-trisphosphate receptor, type 1 | BCL2 protein inhibits the reaction [xestospongin B inhibits the reaction [ITPR1 protein binds to BECN1 protein]] |
affects binding
/ decreases reaction |
protein |
19325567
|
| C078549 | 3708 |
ITPR1
INSP3R1 IP3R IP3R1 SCA15 SCA16 SCA29 |
inositol 1,4,5-trisphosphate receptor, type 1 | xestospongin B inhibits the reaction [ITPR1 protein binds to BECN1 protein] |
affects binding
/ decreases reaction |
protein |
19325567
|