KNApSAcK Metabolite C00046784
Metabolite
KNApSAcK Entry
| id | C00046784 |
|---|---|
| Name | Isoprene |
| CAS RN | 78-79-5 |
| Standard InChI | InChI=1S/C5H8/c1-4-5(2)3/h4H,1-2H2,3H3 |
| Standard InChI (Main Layer) | InChI=1S/C5H8/c1-4-5(2)3/h4H,1-2H2,3H3 |
Cluster
| Phytochemical cluster | No. 33 |
|---|---|
| KCF-S cluster | No. 8935 |
Link
ChEMBL
| By standard InChI | CHEMBL1566132 |
|---|---|
| By standard InChI Main Layer | CHEMBL1566132 |
KEGG
| By LinkDB | C16521 |
|---|
CTD
| By CAS RN | C005059 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Bacillaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Bacillus subtilis 6051 | 186817 | Bacillaceae | Bacteria |
Human Protein / Gene in interaction
4 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P04637 | Cellular tumor antigen p53 | Transcription Factor | CHEMBL1566132 |
CHEMBL1613995
(1)
|
7 / 44 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | CHEMBL1566132 |
CHEMBL1614281
(1)
CHEMBL1614361
(1)
|
3 / 2 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | CHEMBL1566132 |
CHEMBL1614458
(1)
|
0 / 0 |
| P10145 | Interleukin-8 | Secreted protein | CHEMBL1566132 |
CHEMBL2114835
(1)
|
0 / 0 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (10)
| OMIM | preferred title | UniProt |
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #133239 | Esophageal cancer |
P04637
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #211980 | Lung cancer |
P04637
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
KEGG DISEASE (39)
| KEGG | disease name | UniProt |
|---|---|---|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
|
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
Diseases related to CTD interactions
8 disease from interactions of metabolites
| MeSH disease | OMIM | compound | disease name | evidence type |
reference
pmid |
|---|---|---|---|---|---|
| D001943 | C005059 | Breast Neoplasms |
marker/mechanism
|
11921183
|
|
| D007680 | C005059 | Kidney Neoplasms |
marker/mechanism
|
12562636
|
|
| D008114 | C005059 | Liver Neoplasms, Experimental |
marker/mechanism
|
12562636
|
|
| D008175 | C005059 | Lung Neoplasms |
marker/mechanism
|
12562636
|
|
| D015674 | C005059 | Mammary Neoplasms, Animal |
marker/mechanism
|
12562636
|
|
| D008325 | C005059 | Mammary Neoplasms, Experimental |
marker/mechanism
|
11921183
|
|
| D013274 | C005059 | Stomach Neoplasms |
marker/mechanism
|
11397402
12562636 |
|
| D013736 | C005059 | Testicular Neoplasms |
marker/mechanism
|
12562636
|