PCIDB

KNApSAcK Metabolite C00004737

Index

Metabolite

Species

Human Protein
/ Gene in interactions

Related Diseases

Metabolite

KNApSAcK Entry

id	C00004737
Name	Ternatin / Gossypetin 3,7,8,3'-tetramethyl ether / 5,4'-Dihydroxy-3,7,8,3'-tetramethoxyflavone / 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7,8-trimethoxy-4H-1-benzopyran-4-one
CAS RN	571-71-1
Standard InChI	InChI=1S/C19H18O8/c1-23-12-7-9(5-6-10(12)20)16-19(26-4)15(22)14-11(21)8-13(24-2)17(25-3)18(14)27-16/h5-8,20-21H,1-4H3
Standard InChI (Main Layer)	InChI=1S/C19H18O8/c1-23-12-7-9(5-6-10(12)20)16-19(26-4)15(22)14-11(21)8-13(24-2)17(25-3)18(14)27-16/h5-8,20-21H,1-4H3

Cluster

Phytochemical cluster	No. 15
KCF-S cluster	No. 8

Link

ChEMBL

By standard InChI	CHEMBL73991
By standard InChI Main Layer	CHEMBL73991

KEGG

By LinkDB

CTD

By CAS RN	C051080

Species

Summary

Plant class

class name	count
rosids	9
asterids	1
Euphyllophyta	1

Family

family name	count
Rutaceae	6
Zygophyllaceae	2
Calceolariaceae	1
Begoniaceae	1
Ophioglossaceae	1

List (11)

* NCBI

KNApSAcK organism	*ID	*family	*plant class	*kingdom
Begonia glabra	62974	Begoniaceae	rosids	Viridiplantae
Boronia coerulescens	68528	Rutaceae	rosids	Viridiplantae
Calceolaria tenella	219717	Calceolariaceae	asterids	Viridiplantae
Euodia madagascariensis	354493	Rutaceae	rosids	Viridiplantae
Euodia viticina	354493	Rutaceae	rosids	Viridiplantae
Fagonia bruguieri	291458	Zygophyllaceae	rosids	Viridiplantae
Larrea tridentata	66636	Zygophyllaceae	rosids	Viridiplantae
Melicope elleryana	354500	Rutaceae	rosids	Viridiplantae
Melicope simplex	384966	Rutaceae	rosids	Viridiplantae
Melicope ternata	77015	Rutaceae	rosids	Viridiplantae
Sceptridium ternatum	208695	Ophioglossaceae	Euphyllophyta	Viridiplantae

Human Protein / Gene in interaction

15 ChEMBL Protein in interactions

accession	description	class description	compound	assay ID (# of activities)	# of diseases (OMIM / KEGG)
Q13748	Tubulin alpha-3C/D chain	Structural	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
P68366	Tubulin alpha-4A chain	Structural	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q9H4B7	Tubulin beta-1 chain	Structural	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	1 / 0
P04350	Tubulin beta-4A chain	Structural	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	2 / 0
Q3ZCM7	Tubulin beta-8 chain	Structural	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
P07437	Tubulin beta chain	Structural	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q71U36	Tubulin alpha-1A chain	Structural	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	1 / 1
P68371	Tubulin beta-4B chain	Structural	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q13509	Tubulin beta-3 chain	Structural	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	2 / 1
P68363	Tubulin alpha-1B chain	Unclassified protein	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q13885	Tubulin beta-2A chain	Structural	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q6PEY2	Tubulin alpha-3E chain	Unclassified protein	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q9BQE3	Tubulin alpha-1C chain	Unclassified protein	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q9BUF5	Tubulin beta-6 chain	Structural	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	0 / 0
Q9BVA1	Tubulin beta-2B chain	Structural	CHEMBL73991	CHEMBL818984 (1) CHEMBL820476 (1)	1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM	preferred title	UniProt
#614039	Cortical dysplasia, complex, with other brain malformations 1; cdcbm1	Q13509
#128101	Dystonia 4, torsion, autosomal dominant; dyt4	P04350
#600638	Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a	Q13509
#612438	Leukodystrophy, hypomyelinating, 6; hld6	P04350
#611603	Lissencephaly 3; lis3	Q71U36
#613112	Macrothrombocytopenia, autosomal dominant, tubb1-related	Q9H4B7
#610031	Polymicrogyria, symmetric or asymmetric; pmgysa	Q9BVA1

KEGG DISEASE (2)

KEGG	disease name	UniProt
H00838	Congenital fibrosis of the extraocular muscles (CFEOM)	Q13509 (related)
H00268	Lissencephaly (LIS)	Q71U36 (related)