PCIDB

KNApSAcK Metabolite C00047379

Metabolite

KNApSAcK Entry

id C00047379
Name Alterporriol G
CAS RN 1126783-10-5
Standard InChI InChI=1S/C32H26O13/c1-9-5-10-11(6-13(9)33)25(36)17-12(24(10)35)7-15(44-3)20(26(17)37)19-16(45-4)8-14(34)18-21(19)28(39)23-22(27(18)38)29(40)31(42)32(2,43)30(23)41/h5-8,29-31,33-34,37,40-43H,1-4H3
Standard InChI (Main Layer) InChI=1S/C32H26O13/c1-9-5-10-11(6-13(9)33)25(36)17-12(24(10)35)7-15(44-3)20(26(17)37)19-16(45-4)8-14(34)18-21(19)28(39)23-22(27(18)38)29(40)31(42)32(2,43)30(23)41/h5-8,29-31,33-34,37,40-43H,1-4H3

Cluster

Phytochemical cluster
KCF-S cluster No. 1600

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL554993

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count

Family

family name count
Pleosporaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Stemphylium globuliferum 245170 Pleosporaceae Fungi

Human Protein / Gene in interaction

23 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P08069 Insulin-like growth factor 1 receptor TK tyrosine-protein kinase INSR subfamily CHEMBL554993 CHEMBL1026230 (1)
1 / 3
O14965 Aurora kinase A Aur CHEMBL554993 CHEMBL1026220 (1)
0 / 0
P68400 Casein kinase II subunit alpha Ck2 CHEMBL554993 CHEMBL1026239 (1)
0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 CHEMBL554993 CHEMBL1026223 (1)
0 / 0
O00444 Serine/threonine-protein kinase PLK4 PLK serine/threonine protein kinase subfamily CHEMBL554993 CHEMBL1026240 (1)
0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL554993 CHEMBL1026226 (1)
1 / 11
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr CHEMBL554993 CHEMBL1026234 (1)
1 / 1
P54760 Ephrin type-B receptor 4 Eph CHEMBL554993 CHEMBL1026227 (1)
0 / 0
Q05397 Focal adhesion kinase 1 Fak CHEMBL554993 CHEMBL1026229 (1)
0 / 0
Q02763 Angiopoietin-1 receptor Tie CHEMBL554993 CHEMBL1026243 (1)
1 / 1
O60285 NUAK family SNF1-like kinase 1 CAMK serine/threonine protein kinase NUAK subfamily CHEMBL554993 CHEMBL1026219 (1)
0 / 0
P06213 Insulin receptor TK tyrosine-protein kinase INSR subfamily CHEMBL554993 CHEMBL1026235 (1)
5 / 4
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily CHEMBL554993 CHEMBL1026228 (1)
5 / 10
P09619 Platelet-derived growth factor receptor beta Pdgfr CHEMBL554993 CHEMBL1026237 (1)
5 / 1
P12931 Proto-oncogene tyrosine-protein kinase Src Src CHEMBL554993 CHEMBL1026231 (1)
0 / 0
Q96GD4 Aurora kinase B Aur CHEMBL554993 CHEMBL1026221 (1)
0 / 0
P35968 Vascular endothelial growth factor receptor 2 Vegfr CHEMBL554993 CHEMBL1026232 (1)
1 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily CHEMBL554993 CHEMBL1026236 (1)
2 / 3
P35916 Vascular endothelial growth factor receptor 3 Vegfr CHEMBL554993 CHEMBL1026233 (1)
2 / 1
P41279 Mitogen-activated protein kinase kinase kinase 8 Ste11 CHEMBL554993 CHEMBL1026225 (1)
0 / 0
P53350 Serine/threonine-protein kinase PLK1 PLK serine/threonine protein kinase subfamily CHEMBL554993 CHEMBL1026238 (1)
0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt CHEMBL554993 CHEMBL1026218 (1)
4 / 1
P11802 Cyclin-dependent kinase 4 CMGC serine/threonine protein kinase family CHEMBL554993 CHEMBL1026224 (1)
1 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (26)

OMIM preferred title UniProt
#615007 Basal ganglia calcification, idiopathic, 4; ibgc4 P09619
#114480 Breast cancer P31749
#114500 Colorectal cancer; crc P31749
#615109 Cowden syndrome 6; cws6 P31749
#610549 Diabetes mellitus, insulin-resistant, with acanthosis nigricans P06213
#125853 Diabetes mellitus, noninsulin-dependent; niddm P06213
#246200 Donohue syndrome P06213
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#137800 Glioma susceptibility 1; glm1 P04626
#602089 Hemangioma, capillary infantile P35916
P35968
#114550 Hepatocellular carcinoma P08581
#609968 Hyperinsulinemic hypoglycemia, familial, 5; hhf5 P06213
#270450 Insulin-like growth factor i, resistance to P08069
#607785 Juvenile myelomonocytic leukemia; jmml P09619
#601626 Leukemia, acute myeloid; aml P09619
P36888
#211980 Lung cancer P00533
P04626
#153100 Lymphedema, hereditary, ia P35916
#609048 Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 P11802
#131440 Myeloproliferative disorder, chronic, with eosinophilia P09619
#228550 Myofibromatosis, infantile, 1; imf1 P09619
#167000 Ovarian cancer P04626
#262190 Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities P06213
#176920 Proteus syndrome P31749
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#600195 Venous malformations, multiple cutaneous and mucosal; vmcm Q02763

KEGG DISEASE (26)

KEGG disease name UniProt
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P08581 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P04626 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
P11802 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P09619 (related)
P11802 (related)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00019 Pancreatic cancer P04626 (related)
H00026 Endometrial Cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
H00046 Cholangiocarcinoma P04626 (related)
P08581 (related)
H00719 Leprechaunism P06213 (related)
H00942 Rabson-Mendenhall syndrome P06213 (related)
H01228 Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) P06213 (related)
H01267 Familial hyperinsulinemic hypoglycemia (HHF) P06213 (related)
H00015 Malignant pleural mesothelioma P08069 (related)
H00050 Synovial sarcoma P08069 (related)
H01274 Growth delay due to insulin-like growth factor I resistance P08069 (related)
H00021 Renal cell carcinoma P08581 (related)
H00038 Malignant melanoma P11802 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H00535 Lymphedemas P35916 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
H00531 Venous malformations Q02763 (related)