id | C00047828 |
---|---|
Name | Cycloheximide |
CAS RN | 66-81-9 |
Standard InChI | InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1 |
Standard InChI (Main Layer) | InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19) |
Phytochemical cluster | |
---|---|
KCF-S cluster | No. 2705 |
By standard InChI | CHEMBL123292 |
---|---|
By standard InChI Main Layer | CHEMBL123292 CHEMBL356004 CHEMBL225699 CHEMBL600517 CHEMBL582062 CHEMBL1078564 CHEMBL1358722 CHEMBL1552697 |
By LinkDB | C06685 |
---|
By CAS RN | D003513 |
---|
class name | count |
---|
family name | count |
---|---|
Streptomycetaceae | 1 |
KNApSAcK organism | *ID | *family | *plant class | *kingdom |
---|---|---|---|---|
Streptomyces sp. H7667 | 550813 | Streptomycetaceae | Bacteria |
accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|---|
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | CHEMBL123292 CHEMBL1078564 CHEMBL1358722 |
CHEMBL1741321
(2)
CHEMBL1909136
(2)
|
1 / 0 |
P04637 | Cellular tumor antigen p53 | Transcription Factor | CHEMBL123292 |
CHEMBL1613992
(1)
CHEMBL1738132
(1)
|
7 / 44 |
Q16637 | Survival motor neuron protein | Unclassified protein | CHEMBL123292 CHEMBL356004 CHEMBL1358722 CHEMBL1552697 |
CHEMBL1613842
(5)
|
4 / 2 |
P17861 | X-box-binding protein 1 | Unclassified protein | CHEMBL1358722 |
CHEMBL1738682
(1)
|
1 / 0 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | CHEMBL1358722 |
CHEMBL1738312
(1)
|
0 / 0 |
Q99700 | Ataxin-2 | Unclassified protein | CHEMBL123292 CHEMBL1358722 |
CHEMBL2114784
(3)
|
1 / 1 |
P21728 | D(1A) dopamine receptor | Dopamine receptor | CHEMBL123292 |
CHEMBL1909139
(2)
|
0 / 0 |
P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | CHEMBL123292 |
CHEMBL965567
(1)
|
0 / 0 |
P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | CHEMBL123292 |
CHEMBL1909131
(2)
|
0 / 3 |
Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | CHEMBL123292 |
CHEMBL1909190
(2)
|
2 / 2 |
P08246 | Neutrophil elastase | S1A | CHEMBL123292 |
CHEMBL1909195
(2)
|
2 / 1 |
P33765 | Adenosine receptor A3 | Adenosine receptor | CHEMBL123292 |
CHEMBL1909215
(2)
|
0 / 0 |
Q16539 | Mitogen-activated protein kinase 14 | p38 | CHEMBL123292 |
CHEMBL1909201
(2)
|
0 / 0 |
P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | CHEMBL123292 |
CHEMBL1909176
(2)
|
0 / 0 |
P29466 | Caspase-1 | C14 | CHEMBL123292 |
CHEMBL1909193
(2)
|
0 / 0 |
P17252 | Protein kinase C alpha type | Alpha | CHEMBL123292 |
CHEMBL1909198
(2)
|
0 / 0 |
P27361 | Mitogen-activated protein kinase 3 | Erk | CHEMBL123292 |
CHEMBL1909199
(2)
|
0 / 0 |
Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | CHEMBL123292 |
CHEMBL1794524
(3)
|
0 / 0 |
P14780 | Matrix metalloproteinase-9 | M10A | CHEMBL123292 |
CHEMBL1909197
(2)
|
2 / 2 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | CHEMBL123292 |
CHEMBL759110
(1)
|
0 / 0 |
P02545 | Prelamin-A/C | Unclassified protein | CHEMBL1358722 CHEMBL1552697 |
CHEMBL1614544
(1)
CHEMBL1614073
(1)
|
11 / 10 |
P37840 | Alpha-synuclein | Unclassified protein | CHEMBL123292 CHEMBL1358722 |
CHEMBL2354282
(2)
|
4 / 2 |
P10828 | Thyroid hormone receptor beta | NR1A2 | CHEMBL123292 |
CHEMBL1794561
(1)
|
3 / 1 |
P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | CHEMBL123292 |
CHEMBL1794371
(1)
CHEMBL1794471
(3)
|
0 / 0 |
P00918 | Carbonic anhydrase 2 | Lyase | CHEMBL123292 |
CHEMBL1909123
(2)
|
1 / 2 |
P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | CHEMBL123292 |
CHEMBL1909092
(2)
|
0 / 1 |
P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | CHEMBL123292 |
CHEMBL965566
(1)
CHEMBL1909169
(2)
|
1 / 1 |
P25021 | Histamine H2 receptor | Histamine receptor | CHEMBL123292 |
CHEMBL1909157
(2)
|
0 / 0 |
P35367 | Histamine H1 receptor | Histamine receptor | CHEMBL123292 |
CHEMBL1909156
(2)
|
0 / 0 |
Q01959 | Sodium-dependent dopamine transporter | Dopamine | CHEMBL123292 |
CHEMBL1909143
(2)
|
1 / 0 |
P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | CHEMBL123292 |
CHEMBL1909174
(2)
|
0 / 0 |
P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | CHEMBL123292 |
CHEMBL1909090
(2)
|
0 / 0 |
P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | CHEMBL123292 |
CHEMBL1909093
(2)
|
0 / 0 |
P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | CHEMBL123292 |
CHEMBL1909127
(2)
|
0 / 0 |
P06241 | Tyrosine-protein kinase Fyn | Src | CHEMBL123292 |
CHEMBL1909204
(2)
|
0 / 0 |
Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | CHEMBL123292 |
CHEMBL1909202
(2)
|
0 / 0 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | CHEMBL123292 CHEMBL1078564 CHEMBL1358722 |
CHEMBL1741325
(2)
CHEMBL1909135
(2)
|
0 / 1 |
P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | CHEMBL123292 |
CHEMBL1909203
(2)
|
1 / 11 |
P11473 | Vitamin D3 receptor | NR1I1 | CHEMBL123292 |
CHEMBL1794376
(2)
|
2 / 3 |
P14416 | D(2) dopamine receptor | Dopamine receptor | CHEMBL123292 |
CHEMBL1909140
(2)
|
2 / 0 |
P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | CHEMBL123292 |
CHEMBL1909130
(2)
|
0 / 0 |
P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | CHEMBL123292 |
CHEMBL1909120
(2)
|
0 / 0 |
P41145 | Kappa-type opioid receptor | Opioid receptor | CHEMBL123292 |
CHEMBL1909181
(2)
|
0 / 0 |
Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | CHEMBL123292 |
CHEMBL1909164
(2)
|
0 / 0 |
P29274 | Adenosine receptor A2a | Adenosine receptor | CHEMBL123292 |
CHEMBL1909214
(2)
|
0 / 0 |
P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | CHEMBL123292 |
CHEMBL1909175
(2)
|
0 / 0 |
P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | CHEMBL123292 |
CHEMBL1909096
(2)
|
1 / 1 |
P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | CHEMBL123292 |
CHEMBL1909118
(2)
|
0 / 0 |
P41968 | Melanocortin receptor 3 | Melanocortin receptor | CHEMBL123292 |
CHEMBL1909166
(2)
|
1 / 0 |
P00352 | Retinal dehydrogenase 1 | Enzyme | CHEMBL123292 CHEMBL1358722 |
CHEMBL1614458
(2)
|
0 / 0 |
Q02790 | Peptidyl-prolyl cis-trans isomerase FKBP4 | Enzyme | CHEMBL123292 |
CHEMBL682338
(1)
|
0 / 0 |
Q00688 | Peptidyl-prolyl cis-trans isomerase FKBP3 | Enzyme | CHEMBL123292 |
CHEMBL682336
(1)
|
0 / 0 |
P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | CHEMBL123292 |
CHEMBL1909133
(2)
|
0 / 0 |
Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | CHEMBL123292 CHEMBL1358722 |
CHEMBL999906
(1)
CHEMBL999907
(1)
CHEMBL999922 (1) CHEMBL999923 (1) CHEMBL1614456 (1) CHEMBL1613803 (1) |
0 / 0 |
P42858 | Huntingtin | Unclassified protein | CHEMBL1358722 |
CHEMBL1613918
(1)
|
1 / 1 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | CHEMBL123292 CHEMBL1358722 |
CHEMBL1794584
(2)
|
2 / 0 |
O75496 | Geminin | Unclassified protein | CHEMBL123292 CHEMBL1358722 |
CHEMBL2114843
(2)
CHEMBL2114780
(1)
|
0 / 0 |
P51151 | Ras-related protein Rab-9A | Unclassified protein | CHEMBL123292 CHEMBL1358722 |
CHEMBL1613838
(2)
|
0 / 0 |
P13639 | Elongation factor 2 | Unclassified protein | CHEMBL123292 |
CHEMBL1228366
(1)
CHEMBL1228367
(1)
CHEMBL1228368 (1) |
0 / 0 |
P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | CHEMBL123292 |
CHEMBL1909158
(2)
|
0 / 0 |
P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | CHEMBL123292 |
CHEMBL1909088
(2)
|
0 / 0 |
P21917 | D(4) dopamine receptor | Dopamine receptor | CHEMBL123292 |
CHEMBL1909142
(2)
|
0 / 0 |
P30988 | Calcitonin receptor | Calcitonin receptor | CHEMBL123292 |
CHEMBL1909101
(2)
|
0 / 0 |
P35462 | D(3) dopamine receptor | Dopamine receptor | CHEMBL123292 |
CHEMBL1909141
(2)
|
1 / 0 |
P41143 | Delta-type opioid receptor | Opioid receptor | CHEMBL123292 |
CHEMBL1909180
(2)
|
0 / 0 |
Q92731 | Estrogen receptor beta | NR3A2 | CHEMBL123292 |
CHEMBL1909146
(2)
|
0 / 1 |
P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | CHEMBL123292 |
CHEMBL1909104
(2)
|
0 / 0 |
P25101 | Endothelin-1 receptor | Endothelin receptor | CHEMBL123292 |
CHEMBL1909144
(2)
|
0 / 0 |
P30411 | B2 bradykinin receptor | Bradykinin receptor | CHEMBL123292 |
CHEMBL1909100
(2)
|
0 / 0 |
P10145 | Interleukin-8 | Secreted protein | CHEMBL123292 |
CHEMBL2114835
(1)
|
0 / 0 |
P32245 | Melanocortin receptor 4 | Melanocortin receptor | CHEMBL123292 |
CHEMBL1909167
(2)
|
1 / 0 |
Q9Y237 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 | Enzyme | CHEMBL123292 |
CHEMBL759483
(1)
|
0 / 0 |
P49841 | Glycogen synthase kinase-3 beta | Gsk | CHEMBL123292 CHEMBL1078564 |
CHEMBL1113068
(2)
CHEMBL1113069
(2)
CHEMBL1113070 (2) CHEMBL1113071 (2) CHEMBL1113072 (2) CHEMBL1113073 (2) CHEMBL1113074 (2) CHEMBL1113075 (2) |
0 / 0 |
P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | CHEMBL123292 |
CHEMBL1909129
(2)
|
0 / 0 |
P08311 | Cathepsin G | S1A | CHEMBL123292 |
CHEMBL1909194
(2)
|
0 / 0 |
Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | CHEMBL123292 |
CHEMBL1909110
(2)
|
1 / 0 |
P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | CHEMBL123292 CHEMBL1358722 |
CHEMBL2114788
(2)
|
0 / 0 |
Q9NWM8 | Peptidyl-prolyl cis-trans isomerase FKBP14 | Enzyme | CHEMBL123292 |
CHEMBL682335
(1)
|
1 / 0 |
P03956 | Interstitial collagenase | M10A | CHEMBL123292 |
CHEMBL1909196
(2)
|
0 / 1 |
P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | CHEMBL123292 |
CHEMBL1909119
(2)
|
0 / 0 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | CHEMBL123292 |
CHEMBL1794401
(1)
|
0 / 0 |
P04150 | Glucocorticoid receptor | NR3C1 | CHEMBL123292 |
CHEMBL1794382
(3)
CHEMBL1909150
(2)
|
0 / 1 |
P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | CHEMBL123292 |
CHEMBL1909171
(2)
|
2 / 0 |
P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | CHEMBL123292 |
CHEMBL1909170
(2)
|
0 / 0 |
P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | CHEMBL123292 |
CHEMBL1909122
(2)
|
0 / 0 |
P31645 | Sodium-dependent serotonin transporter | Serotonin | CHEMBL123292 |
CHEMBL1909109
(2)
|
2 / 0 |
P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | CHEMBL123292 |
CHEMBL1794293
(1)
CHEMBL1794510
(2)
|
5 / 3 |
P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | CHEMBL123292 |
CHEMBL1909205
(2)
|
5 / 10 |
P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | CHEMBL123292 |
CHEMBL1909172
(2)
|
1 / 0 |
P21452 | Substance-K receptor | Neurokinin receptor | CHEMBL123292 |
CHEMBL1909114
(2)
|
0 / 0 |
P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | CHEMBL123292 |
CHEMBL1909125
(2)
|
0 / 0 |
P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | CHEMBL123292 |
CHEMBL1909126
(2)
|
3 / 0 |
P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | CHEMBL123292 |
CHEMBL1909108
(2)
|
0 / 0 |
Q96RI1 | Bile acid receptor | NR1H4 | CHEMBL123292 |
CHEMBL1794437
(1)
|
0 / 0 |
P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | CHEMBL123292 |
CHEMBL1909124
(2)
|
1 / 0 |
P28482 | Mitogen-activated protein kinase 1 | Erk | CHEMBL123292 CHEMBL1552697 |
CHEMBL1613808
(1)
CHEMBL1909200
(2)
|
0 / 0 |
P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | CHEMBL123292 |
CHEMBL1909207
(2)
|
2 / 1 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | CHEMBL123292 CHEMBL1078564 CHEMBL1358722 |
CHEMBL1741322
(2)
CHEMBL1909132
(2)
|
0 / 0 |
P27540 | Aryl hydrocarbon receptor nuclear translocator | Unclassified protein | CHEMBL123292 |
CHEMBL999908
(1)
CHEMBL999909
(1)
|
0 / 0 |
O15118 | Niemann-Pick C1 protein | Unclassified protein | CHEMBL123292 CHEMBL1358722 |
CHEMBL1614342
(2)
|
1 / 1 |
P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | CHEMBL123292 |
CHEMBL2114842
(2)
|
0 / 0 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | CHEMBL123292 CHEMBL1358722 |
CHEMBL1738588
(2)
|
0 / 0 |
O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | CHEMBL123292 |
CHEMBL1909186
(2)
|
0 / 0 |
P03372 | Estrogen receptor | NR3A1 | CHEMBL123292 |
CHEMBL1794542
(3)
CHEMBL1909145
(2)
|
1 / 1 |
P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | CHEMBL123292 |
CHEMBL1909091
(2)
|
1 / 0 |
P62942 | Peptidyl-prolyl cis-trans isomerase FKBP1A | Isomerase | CHEMBL123292 |
CHEMBL678140
(1)
CHEMBL678144
(1)
|
0 / 0 |
P22303 | Acetylcholinesterase | Hydrolase | CHEMBL123292 |
CHEMBL1909212
(2)
|
1 / 0 |
P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | CHEMBL123292 |
CHEMBL1909211
(2)
|
0 / 0 |
P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | CHEMBL123292 |
CHEMBL1909105
(2)
|
0 / 0 |
P35372 | Mu-type opioid receptor | Opioid receptor | CHEMBL123292 |
CHEMBL1909182
(2)
|
0 / 0 |
P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | CHEMBL123292 |
CHEMBL1909173
(2)
|
0 / 0 |
P25103 | Substance-P receptor | Neurokinin receptor | CHEMBL123292 |
CHEMBL1909113
(2)
|
0 / 0 |
P25105 | Platelet-activating factor receptor | PAF receptor | CHEMBL123292 |
CHEMBL1909187
(2)
|
0 / 0 |
P33032 | Melanocortin receptor 5 | Melanocortin receptor | CHEMBL123292 |
CHEMBL1909168
(2)
|
0 / 0 |
P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | CHEMBL123292 |
CHEMBL2114853
(2)
|
0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | CHEMBL123292 CHEMBL1078564 CHEMBL1358722 |
CHEMBL1613777
(1)
CHEMBL1741323
(2)
CHEMBL1909134 (2) |
1 / 1 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL123292 CHEMBL1078564 CHEMBL1358722 |
CHEMBL1614108
(1)
CHEMBL1613886
(1)
CHEMBL1741324 (2) CHEMBL1909138 (2) |
0 / 1 |
P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | CHEMBL123292 |
CHEMBL1909137
(2)
|
0 / 0 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | CHEMBL123292 CHEMBL1358722 |
CHEMBL1738184
(2)
CHEMBL2114890
(3)
|
0 / 0 |
P10275 | Androgen receptor | NR3C4 | CHEMBL123292 |
CHEMBL1794321
(3)
CHEMBL1794560
(2)
|
3 / 4 |
P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | CHEMBL123292 |
CHEMBL1909094
(2)
|
1 / 1 |
P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | CHEMBL123292 |
CHEMBL1909087
(2)
|
0 / 0 |
P30542 | Adenosine receptor A1 | Adenosine receptor | CHEMBL123292 |
CHEMBL1909213
(2)
|
0 / 0 |
P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | CHEMBL123292 |
CHEMBL1909089
(2)
|
0 / 0 |
P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | CHEMBL123292 |
CHEMBL1909116
(2)
|
1 / 1 |
P06239 | Tyrosine-protein kinase Lck | Src | CHEMBL123292 |
CHEMBL1909206
(2)
|
0 / 1 |
P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | CHEMBL123292 |
CHEMBL1909128
(2)
|
0 / 0 |
P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | CHEMBL123292 CHEMBL1358722 |
CHEMBL1794333
(2)
|
0 / 0 |
P68104 | Elongation factor 1-alpha 1 | Unclassified protein | CHEMBL123292 |
CHEMBL1228364
(1)
|
0 / 0 |
O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | CHEMBL123292 CHEMBL1358722 |
CHEMBL2354311
(2)
|
1 / 0 |
Q13148 | TAR DNA-binding protein 43 | Unclassified protein | CHEMBL123292 CHEMBL1358722 |
CHEMBL2354287
(2)
|
1 / 1 |
compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
---|---|---|---|---|---|---|---|
D003513 | 5243 |
ABCB1
ABC20 CD243 CLCS GP170 MDR1 P-GP PGY1 |
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) | Cycloheximide promotes the reaction [Reserpine results in increased expression of ABCB1 mRNA] |
increases expression
/ increases reaction |
mRNA |
7476894
|
D003513 | 5243 |
ABCB1
ABC20 CD243 CLCS GP170 MDR1 P-GP PGY1 |
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) | Cycloheximide results in increased expression of ABCB1 mRNA |
increases expression
|
mRNA |
7476894
|
D003513 | 5244 |
ABCB4
ABC21 GBD1 ICP3 MDR2 MDR2/3 MDR3 PFIC-3 PGY3 |
ATP-binding cassette, sub-family B (MDR/TAP), member 4 (EC:3.6.3.44) | Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11331069
|
D003513 | 8714 |
ABCC3
ABC31 EST90757 MLP2 MOAT-D MRP3 cMOAT2 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | [Cycloheximide co-treated with Estradiol] results in increased expression of ABCC3 mRNA |
affects cotreatment
/ increases expression |
mRNA |
15072547
|
D003513 | 8714 |
ABCC3
ABC31 EST90757 MLP2 MOAT-D MRP3 cMOAT2 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | Cycloheximide results in increased expression of ABCC3 mRNA |
increases expression
|
mRNA |
15072547
|
D003513 | 10057 |
ABCC5
ABC33 EST277145 MOAT-C MOATC MRP5 SMRP pABC11 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | [Cycloheximide co-treated with Estradiol] results in decreased expression of ABCC5 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
15072547
|
D003513 | 10057 |
ABCC5
ABC33 EST277145 MOAT-C MOATC MRP5 SMRP pABC11 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | Cycloheximide results in decreased expression of ABCC5 mRNA |
decreases expression
|
mRNA |
15072547
|
D003513 | 2181 |
ACSL3
ACS3 FACL3 PRO2194 |
acyl-CoA synthetase long-chain family member 3 (EC:6.2.1.3) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of ACSL3 mRNA |
affects cotreatment
/ affects expression |
mRNA |
19684285
|
D003513 | 8754 |
ADAM9
CORD9 MCMP MDC9 Mltng |
ADAM metallopeptidase domain 9 | Cycloheximide inhibits the reaction [Hydrogen Peroxide results in increased expression of ADAM9 protein] |
decreases reaction
/ increases expression |
protein |
17018608
|
D003513 | 133 |
ADM
AM |
adrenomedullin | Cycloheximide promotes the reaction [Oxygen deficiency results in increased expression of ADM mRNA] |
increases expression
/ increases reaction |
mRNA |
11032871
|
D003513 | 133 |
ADM
AM |
adrenomedullin | Cycloheximide results in increased expression of ADM mRNA |
increases expression
|
mRNA |
11032871
|
D003513 | 136 |
ADORA2B
ADORA2 |
adenosine A2b receptor | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ADORA2B mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 196 |
AHR
bHLHe76 |
aryl hydrocarbon receptor | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of AHR protein] |
decreases expression
/ decreases reaction |
protein |
15385644
|
D003513 | 196 |
AHR
bHLHe76 |
aryl hydrocarbon receptor | Cycloheximide inhibits the reaction [TGFB1 protein results in decreased expression of AHR mRNA] |
decreases expression
/ decreases reaction |
mRNA |
9145908
|
D003513 | 196 |
AHR
bHLHe76 |
aryl hydrocarbon receptor | Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased degradation of and results in decreased expression of AHR protein] |
decreases expression
/ increases degradation / increases reaction |
protein |
15385644
|
D003513 | 196 |
AHR
bHLHe76 |
aryl hydrocarbon receptor | Cycloheximide results in decreased expression of AHR protein |
decreases expression
|
protein |
15385644
|
D003513 | 9495 |
AKAP5
AKAP75 AKAP79 H21 |
A kinase (PRKA) anchor protein 5 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AKAP5 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 9472 |
AKAP6
ADAP100 ADAP6 AKAP100 PRKA6 mAKAP |
A kinase (PRKA) anchor protein 6 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AKAP6 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 220 |
ALDH1A3
ALDH1A6 ALDH6 MCOP8 RALDH3 |
aldehyde dehydrogenase 1 family, member A3 (EC:1.2.1.5) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ALDH1A3 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 224 |
ALDH3A2
ALDH10 FALDH SLS |
aldehyde dehydrogenase 3 family, member A2 (EC:1.2.1.3) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ALDH3A2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 241 |
ALOX5AP
FLAP |
arachidonate 5-lipoxygenase-activating protein | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ALOX5AP mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 248 |
ALPI
IAP |
alkaline phosphatase, intestinal (EC:3.1.3.1) | Cycloheximide results in decreased activity of ALPI protein |
decreases activity
|
protein |
20362602
|
D003513 | 269 |
AMHR2
AMHR MISR2 MISRII MRII |
anti-Mullerian hormone receptor, type II (EC:2.7.11.30) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AMHR2 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 287 |
ANK2
ANK-2 LQT4 brank-2 |
ankyrin 2, neuronal | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ANK2 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 84079 |
ANKRD27
VARP |
ankyrin repeat domain 27 (VPS9 domain) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ANKRD27 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 317 |
APAF1
APAF-1 CED4 |
apoptotic peptidase activating factor 1 | Cycloheximide results in decreased expression of APAF1 mRNA |
decreases expression
|
mRNA |
19684285
|
D003513 | 317 |
APAF1
APAF-1 CED4 |
apoptotic peptidase activating factor 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of APAF1 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
19684285
|
D003513 | 374 |
AREG
AR CRDGF SDGF |
amphiregulin | [Cycloheximide co-treated with Estradiol] results in increased expression of AREG mRNA |
affects cotreatment
/ increases expression |
mRNA |
15072547
|
D003513 | 374 |
AREG
AR CRDGF SDGF |
amphiregulin | Cycloheximide results in increased expression of AREG mRNA |
increases expression
|
mRNA |
15072547
15228094 |
D003513 | 79798 |
ARMC5
|
armadillo repeat containing 5 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ARMC5 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 51665 |
ASB1
ASB-1 |
ankyrin repeat and SOCS box containing 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ASB1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 468 |
ATF4
CREB-2 CREB2 TAXREB67 TXREB |
activating transcription factor 4 | Cycloheximide inhibits the reaction [Capsaicin results in increased expression of ATF4 protein] |
decreases reaction
/ increases expression |
protein |
18533110
|
D003513 | 552 |
AVPR1A
AVPR_V1a AVPR1 V1aR |
arginine vasopressin receptor 1A | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AVPR1A mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 8424 |
BBOX1
BBH BBOX G-BBH gamma-BBH |
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 (EC:1.14.11.1) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of BBOX1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 596 |
BCL2
Bcl-2 PPP1R50 |
B-cell CLL/lymphoma 2 | Cycloheximide inhibits the reaction [Paclitaxel results in increased phosphorylation of BCL2 protein] |
decreases reaction
/ increases phosphorylation |
protein |
11726273
|
D003513 | 598 |
BCL2L1
BCL-XL/S BCL2L BCLX BCLXL BCLXS Bcl-X PPP1R52 bcl-xL bcl-xS |
BCL2-like 1 | Cycloheximide results in increased expression of BCL2L1 protein alternative form |
increases expression
|
protein |
9326359
|
D003513 | 598 |
BCL2L1
BCL-XL/S BCL2L BCLX BCLXL BCLXS Bcl-X PPP1R52 bcl-xL bcl-xS |
BCL2-like 1 | Dexamethasone inhibits the reaction [Cycloheximide results in increased expression of BCL2L1 protein] |
decreases reaction
/ increases expression |
protein |
9326359
|
D003513 | 79370 |
BCL2L14
BCLG |
BCL2-like 14 (apoptosis facilitator) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of BCL2L14 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 622 |
BDH1
BDH SDR9C1 |
3-hydroxybutyrate dehydrogenase, type 1 (EC:1.1.1.30) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of BDH1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 8678 |
BECN1
ATG6 VPS30 beclin1 |
beclin 1, autophagy related | Cycloheximide inhibits the reaction [arsenic trioxide results in increased expression of BECN1 protein] |
decreases reaction
/ increases expression |
protein |
16882451
|
D003513 | 637 |
BID
FP497 |
BH3 interacting domain death agonist | [Cycloheximide co-treated with TNF] results in increased cleavage of BID protein |
affects cotreatment
/ increases cleavage |
protein |
12925536
|
D003513 | 637 |
BID
FP497 |
BH3 interacting domain death agonist | Cycloheximide inhibits the reaction [vorinostat results in increased cleavage of BID protein] |
decreases reaction
/ increases cleavage |
protein |
11535817
|
D003513 | 637 |
BID
FP497 |
BH3 interacting domain death agonist | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of BID protein] |
affects cotreatment
/ decreases reaction / increases cleavage |
protein |
12925536
|
D003513 | 637 |
BID
FP497 |
BH3 interacting domain death agonist | ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of BID protein] |
affects cotreatment
/ increases cleavage / increases reaction |
protein |
12925536
|
D003513 | 672 |
BRCA1
BRCAI BRCC1 BROVCA1 IRIS PNCA4 PPP1R53 PSCP RNF53 |
breast cancer 1, early onset | Cycloheximide inhibits the reaction [Nitrogen Mustard Compounds results in decreased expression of BRCA1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
10344722
|
D003513 | 675 |
BRCA2
BRCC2 BROVCA2 FACD FAD FAD1 FANCB FANCD FANCD1 GLM3 PNCA2 |
breast cancer 2, early onset | Cycloheximide inhibits the reaction [Nitrogen Mustard Compounds results in decreased expression of BRCA2 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
10344722
|
D003513 | 90488 |
C12orf23
|
chromosome 12 open reading frame 23 | Cycloheximide results in increased expression of C12ORF23 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 90488 |
C12orf23
|
chromosome 12 open reading frame 23 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of C12ORF23 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 793 |
CALB1
CALB |
calbindin 1, 28kDa | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CALB1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 819 |
CAMLG
CAML |
calcium modulating ligand | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CAMLG mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 834 |
CASP1
ICE IL1BC P45 |
caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CASP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein] |
affects cotreatment
/ decreases reaction / increases activity / increases cleavage |
protein |
18222423
|
D003513 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | [Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein |
affects cotreatment
/ increases activity / increases cleavage |
protein |
12925536
|
D003513 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP3 protein] |
increases activity
/ increases reaction |
protein |
12760867
|
D003513 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | Cycloheximide results in increased activity of CASP3 protein |
increases activity
|
protein |
15685448
|
D003513 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | IFI6 protein inhibits the reaction [Cycloheximide results in increased activity of CASP3 protein] |
decreases reaction
/ increases activity |
protein |
15685448
|
D003513 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein] |
affects cotreatment
/ decreases reaction / increases activity / increases cleavage |
protein |
12925536
|
D003513 | 837 |
CASP4
ICE(rel)II ICEREL-II ICH-2 Mih1/TX TX |
caspase 4, apoptosis-related cysteine peptidase (EC:3.4.22.57) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CASP4 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 840 |
CASP7
CASP-7 CMH-1 ICE-LAP3 LICE2 MCH3 |
caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) | Cycloheximide inhibits the reaction [Tretinoin results in increased expression of CASP7 mRNA] |
decreases reaction
/ increases expression |
mRNA |
16166294
|
D003513 | 840 |
CASP7
CASP-7 CMH-1 ICE-LAP3 LICE2 MCH3 |
caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) | Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP7 protein] |
increases activity
/ increases reaction |
protein |
12760867
|
D003513 | 841 |
CASP8
ALPS2B CAP4 Casp-8 FLICE MACH MCH5 |
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) | benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein] |
affects cotreatment
/ decreases reaction / increases activity / increases cleavage |
protein |
18222423
|
D003513 | 841 |
CASP8
ALPS2B CAP4 Casp-8 FLICE MACH MCH5 |
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) | [Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein |
affects cotreatment
/ increases activity / increases cleavage |
protein |
12925536
|
D003513 | 841 |
CASP8
ALPS2B CAP4 Casp-8 FLICE MACH MCH5 |
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) | [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein |
affects cotreatment
/ increases activity / increases cleavage |
protein |
18222423
|
D003513 | 841 |
CASP8
ALPS2B CAP4 Casp-8 FLICE MACH MCH5 |
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) | Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP8 protein] |
increases activity
/ increases reaction |
protein |
12760867
|
D003513 | 841 |
CASP8
ALPS2B CAP4 Casp-8 FLICE MACH MCH5 |
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) | Cycloheximide results in increased activity of CASP8 protein |
increases activity
|
protein |
15924153
|
D003513 | 841 |
CASP8
ALPS2B CAP4 Casp-8 FLICE MACH MCH5 |
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein] |
affects cotreatment
/ decreases reaction / increases activity / increases cleavage |
protein |
12925536
|
D003513 | 842 |
CASP9
APAF-3 APAF3 ICE-LAP6 MCH6 PPP1R56 |
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) | [Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein |
affects cotreatment
/ increases activity |
protein |
12925536
|
D003513 | 842 |
CASP9
APAF-3 APAF3 ICE-LAP6 MCH6 PPP1R56 |
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) | [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP9 protein |
affects cotreatment
/ increases activity / increases cleavage |
protein |
18222423
|
D003513 | 842 |
CASP9
APAF-3 APAF3 ICE-LAP6 MCH6 PPP1R56 |
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
12925536
|
D003513 | 857 |
CAV1
BSCL3 CGL3 MSTP085 PPH3 VIP21 CAV |
caveolin 1, caveolae protein, 22kDa | Cycloheximide inhibits the reaction [rosiglitazone results in increased expression of CAV1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15314095
|
D003513 | 10951 |
CBX1
CBX HP1-BETA HP1Hs-beta HP1Hsbeta M31 MOD1 p25beta |
chromobox homolog 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CBX1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 6347 |
CCL2
GDCF-2 HC11 HSMCR30 MCAF MCP-1 MCP1 SCYA2 SMC-CF |
chemokine (C-C motif) ligand 2 | Cycloheximide results in increased expression of CCL2 mRNA |
increases expression
|
mRNA |
21146893
|
D003513 | 6347 |
CCL2
GDCF-2 HC11 HSMCR30 MCAF MCP-1 MCP1 SCYA2 SMC-CF |
chemokine (C-C motif) ligand 2 | TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL2 mRNA] |
increases expression
/ increases reaction |
mRNA |
21146893
|
D003513 | 6347 |
CCL2
GDCF-2 HC11 HSMCR30 MCAF MCP-1 MCP1 SCYA2 SMC-CF |
chemokine (C-C motif) ligand 2 | Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL2 mRNA]] |
decreases reaction
/ increases expression / increases reaction |
mRNA |
21146893
|
D003513 | 6352 |
CCL5
D17S136E RANTES SCYA5 SIS-delta SISd TCP228 eoCP |
chemokine (C-C motif) ligand 5 | Cycloheximide results in increased expression of CCL5 mRNA |
increases expression
|
mRNA |
21146893
|
D003513 | 6352 |
CCL5
D17S136E RANTES SCYA5 SIS-delta SISd TCP228 eoCP |
chemokine (C-C motif) ligand 5 | TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL5 mRNA] |
increases expression
/ increases reaction |
mRNA |
21146893
|
D003513 | 6352 |
CCL5
D17S136E RANTES SCYA5 SIS-delta SISd TCP228 eoCP |
chemokine (C-C motif) ligand 5 | Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL5 mRNA]] |
decreases reaction
/ increases expression / increases reaction |
mRNA |
21146893
|
D003513 | 890 |
CCNA2
CCN1 CCNA |
cyclin A2 | [Cycloheximide co-treated with Estradiol] results in increased expression of CCNA2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
15072547
|
D003513 | 890 |
CCNA2
CCN1 CCNA |
cyclin A2 | Cycloheximide results in decreased expression of CCNA2 mRNA |
decreases expression
|
mRNA |
15072547
|
D003513 | 595 |
CCND1
BCL1 D11S287E PRAD1 U21B31 |
cyclin D1 | Cycloheximide inhibits the reaction [IL8 protein results in increased expression of CCND1 protein] |
decreases reaction
/ increases expression |
protein |
17606477
|
D003513 | 595 |
CCND1
BCL1 D11S287E PRAD1 U21B31 |
cyclin D1 | [gingerol co-treated with Cycloheximide] results in increased degradation of CCND1 protein |
affects cotreatment
/ increases degradation |
protein |
18058799
|
D003513 | 22948 |
CCT5
CCT-epsilon CCTE TCP-1-epsilon |
chaperonin containing TCP1, subunit 5 (epsilon) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of CCT5 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
19684285
|
D003513 | 952 |
CD38
T10 |
CD38 molecule (EC:3.2.2.5) | Cycloheximide affects the reaction [Tretinoin results in increased expression of CD38 mRNA] |
affects reaction
/ increases expression |
mRNA |
21393419
|
D003513 | 916 |
CD3E
T3E TCRE |
CD3e molecule, epsilon (CD3-TCR complex) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CD3E mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 961 |
CD47
IAP MER6 OA3 |
CD47 molecule | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CD47 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 967 |
CD63
LAMP-3 ME491 MLA1 OMA81H TSPAN30 |
CD63 molecule | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CD63 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 925 |
CD8A
CD8 Leu2 MAL p32 |
CD8a molecule | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CD8A mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 56990 |
CDC42SE2
SPEC2 |
CDC42 small effector 2 | Cycloheximide results in increased expression of CDC42SE2 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 56990 |
CDC42SE2
SPEC2 |
CDC42 small effector 2 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of CDC42SE2 mRNA |
affects cotreatment
/ affects expression |
mRNA |
19684285
|
D003513 | 113130 |
CDCA5
SORORIN |
cell division cycle associated 5 | Cycloheximide results in increased expression of CDCA5 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 113130 |
CDCA5
SORORIN |
cell division cycle associated 5 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CDCA5 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 1017 |
CDK2
p33(CDK2) |
cyclin-dependent kinase 2 (EC:2.7.11.22) | Cycloheximide inhibits the reaction [Dexamethasone results in decreased expression of CDK2 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
12800980
|
D003513 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | Cycloheximide inhibits the reaction [resveratrol results in increased expression of CDKN1A mRNA] |
decreases reaction
/ increases expression |
mRNA |
12690110
|
D003513 | 1026 |
CDKN1A
CAP20 CDKN1 CIP1 MDA-6 P21 SDI1 WAF1 p21CIP1 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) | Cycloheximide inhibits the reaction [troglitazone results in increased expression of CDKN1A protein] |
decreases reaction
/ increases expression |
protein |
10441511
|
D003513 | 1029 |
CDKN2A
ARF CDK4I CDKN2 CMM2 INK4 INK4A MLM MTS-1 MTS1 P14 P14ARF P16 P16-INK4A P16INK4 P16INK4A P19 P19ARF TP16 |
cyclin-dependent kinase inhibitor 2A | Cycloheximide results in increased expression of CDKN2A mRNA |
increases expression
|
mRNA |
17257637
|
D003513 | 8837 |
CFLAR
CASH CASP8AP1 CLARP Casper FLAME FLAME-1 FLAME1 FLIP I-FLICE MRIT c-FLIP c-FLIPL c-FLIPR c-FLIPS |
CASP8 and FADD-like apoptosis regulator | Cycloheximide results in decreased expression of CFLAR protein |
decreases expression
|
protein |
12663669
16077199 16951203 |
D003513 | 8837 |
CFLAR
CASH CASP8AP1 CLARP Casper FLAME FLAME-1 FLAME1 FLIP I-FLICE MRIT c-FLIP c-FLIPL c-FLIPR c-FLIPS |
CASP8 and FADD-like apoptosis regulator | Cycloheximide results in decreased expression of CFLAR protein alternative form |
decreases expression
|
protein |
15924153
|
D003513 | 1128 |
CHRM1
HM1 M1 M1R |
cholinergic receptor, muscarinic 1 | Cycloheximide inhibits the reaction [Dihydrotestosterone results in decreased expression of CHRM1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
17624924
|
D003513 | 10370 |
CITED2
ASD8 MRG-1 MRG1 P35SRJ VSD2 |
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of CITED2 mRNA |
affects cotreatment
/ affects expression |
mRNA |
19684285
|
D003513 | 1182 |
CLCN3
CLC3 ClC-3 |
chloride channel, voltage-sensitive 3 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CLCN3 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 1268 |
CNR1
CANN6 CB-R CB1 CB1A CB1K5 CB1R CNR |
cannabinoid receptor 1 (brain) | Cycloheximide inhibits the reaction [Dronabinol results in increased expression of CNR1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
17041005
|
D003513 | 51084 |
CRYL1
GDH lambda-CRY |
crystallin, lambda 1 (EC:1.1.1.45) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CRYL1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 1437 |
CSF2
GMCSF |
colony stimulating factor 2 (granulocyte-macrophage) | Cycloheximide inhibits the reaction [IL1B results in increased secretion of CSF2 protein] |
decreases reaction
/ increases secretion |
protein |
9606035
|
D003513 | 1453 |
CSNK1D
ASPS CKIdelta FASPS2 HCKID |
casein kinase 1, delta (EC:2.7.11.1 2.7.11.26) | Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of CSNK1D mRNA] |
decreases expression
/ increases reaction |
mRNA |
11007951
|
D003513 | 1490 |
CTGF
CCN2 HCS24 IGFBP8 NOV2 |
connective tissue growth factor | Cycloheximide results in increased expression of CTGF mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 1490 |
CTGF
CCN2 HCS24 IGFBP8 NOV2 |
connective tissue growth factor | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of CTGF mRNA |
affects cotreatment
/ decreases expression |
mRNA |
19684285
|
D003513 | 54205 |
CYCS
CYC HCS THC4 |
cytochrome c, somatic | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYCS mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 1588 |
CYP19A1
ARO ARO1 CPV1 CYAR CYP19 CYPXIX P-450AROM |
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) | Cycloheximide results in decreased activity of CYP19A1 protein |
decreases activity
|
protein |
16480277
|
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | 3'-methoxy-4'-nitroflavone inhibits the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15385644
|
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | alpha-naphthoflavone inhibits the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15385644
|
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | Benzimidazoles promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA] |
increases expression
/ increases reaction |
mRNA |
8647108
|
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cycloheximide co-treated with Harmaline] results in decreased expression of CYP1A1 protein] |
affects cotreatment
/ decreases expression / decreases reaction |
protein |
22037238
|
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cycloheximide co-treated with harmalol] results in decreased expression of CYP1A1 protein] |
affects cotreatment
/ decreases expression / decreases reaction |
protein |
22037238
|
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | beta-Naphthoflavone promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA] |
increases expression
/ increases reaction |
mRNA |
8647108
|
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | [Cycloheximide co-treated with Harmaline] results in decreased expression of CYP1A1 protein |
affects cotreatment
/ decreases expression |
protein |
22037238
|
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | [Cycloheximide co-treated with harmalol] results in decreased expression of CYP1A1 protein |
affects cotreatment
/ decreases expression |
protein |
22037238
|
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | [Cycloheximide co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1A1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
15385644
|
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | Cycloheximide inhibits the reaction [TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] |
decreases reaction
/ increases expression |
mRNA |
9145908
|
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | Cycloheximide promotes the reaction [Skatole results in increased expression of CYP1A1 mRNA] |
increases expression
/ increases reaction |
mRNA |
20187624
|
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] |
increases expression
/ increases reaction |
mRNA |
9102211
17599377 |
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | Cycloheximide results in increased expression of CYP1A1 mRNA |
increases expression
|
mRNA |
8647108
15385644 19244278 19684285 |
D003513 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CYP1A1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 1545 |
CYP1B1
CP1B CYPIB1 GLC3A P4501B1 |
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | Cycloheximide inhibits the reaction [TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]] |
decreases reaction
/ increases expression |
mRNA |
9145908
|
D003513 | 1545 |
CYP1B1
CP1B CYPIB1 GLC3A P4501B1 |
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | Cycloheximide results in increased expression of CYP1B1 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 1545 |
CYP1B1
CP1B CYPIB1 GLC3A P4501B1 |
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CYP1B1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 1591 |
CYP24A1
CP24 CYP24 HCAI P450-CC24 |
cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) | alpha-naphthoflavone inhibits the reaction [Cycloheximide promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]] |
decreases reaction
/ increases expression / increases reaction |
mRNA |
19244278
|
D003513 | 1591 |
CYP24A1
CP24 CYP24 HCAI P450-CC24 |
cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) | Cycloheximide inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
19244278
|
D003513 | 1548 |
CYP2A6
CPA6 CYP2A CYP2A3 CYPIIA6 P450C2A P450PB |
cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) | Bilirubin inhibits the reaction [Cycloheximide results in decreased expression of CYP2A6 protein] |
decreases expression
/ decreases reaction |
protein |
22465937
|
D003513 | 1548 |
CYP2A6
CPA6 CYP2A CYP2A3 CYPIIA6 P450C2A P450PB |
cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) | Cycloheximide results in decreased expression of CYP2A6 protein |
decreases expression
|
protein |
22465937
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | (4-amidinophenyl)methanesulfonyl fluoride inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] |
decreases reaction
/ increases degradation |
protein |
9143349
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] |
decreases reaction
/ increases degradation |
protein |
9143349
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | acetonitrile inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] |
decreases reaction
/ increases degradation |
protein |
9143349
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | Biotin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] |
decreases reaction
/ increases degradation |
protein |
9143349
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | Carbon Tetrachloride promotes the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] |
increases degradation
/ increases reaction |
protein |
9143349
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] |
decreases reaction
/ increases oxidation |
protein |
8531136
9143349 |
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] |
decreases reaction
/ increases oxidation / increases reaction |
protein |
9143349
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | Cycloheximide promotes the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein] |
increases degradation
/ increases reaction |
protein |
8531136
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | Cycloheximide results in increased degradation of CYP2E1 protein |
increases degradation
|
protein |
9143349
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] |
decreases reaction
/ increases degradation |
protein |
9143349
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | Edetic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] |
decreases reaction
/ increases degradation |
protein |
9143349
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | Egtazic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] |
decreases reaction
/ increases degradation |
protein |
9143349
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | Ethanol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] |
decreases reaction
/ increases degradation |
protein |
9143349
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | fomepizole inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] |
decreases reaction
/ increases degradation |
protein |
9143349
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | Glycerol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] |
decreases reaction
/ increases degradation |
protein |
9143349
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | leupeptin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] |
decreases reaction
/ increases degradation |
protein |
9143349
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | Tetradecanoylphorbol Acetate inhibits the reaction [Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] |
decreases reaction
/ increases oxidation |
protein |
8531136
|
D003513 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | Tosyllysine Chloromethyl Ketone inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] |
decreases reaction
/ increases degradation |
protein |
9143349
|
D003513 | 1572 |
CYP2F1
C2F1 CYP2F |
cytochrome P450, family 2, subfamily F, polypeptide 1 (EC:1.14.14.1) | Cycloheximide inhibits the reaction [Skatole results in increased expression of CYP2F1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
20187624
|
D003513 | 1576 |
CYP3A4
CP33 CP34 CYP3A CYP3A3 CYPIIIA3 CYPIIIA4 HLP NF-25 P450C3 P450PCN1 |
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) | Cycloheximide results in decreased expression of CYP3A4 mRNA |
decreases expression
|
mRNA |
21466820
|
D003513 | 3491 |
CYR61
CCN1 GIG1 IGFBP10 |
cysteine-rich, angiogenic inducer, 61 | Cycloheximide inhibits the reaction [Acetylcysteine results in increased expression of CYR61 protein] |
decreases reaction
/ increases expression |
protein |
21055460
|
D003513 | 1605 |
DAG1
156DAG A3a AGRNR DAG MDDGC7 MDDGC9 |
dystroglycan 1 (dystrophin-associated glycoprotein 1) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DAG1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 1634 |
DCN
CSCD DSPG2 PG40 PGII PGS2 SLRR1B |
decorin | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DCN mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 10522 |
DEAF1
NUDR SPN ZMYND5 |
DEAF1 transcription factor | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of DEAF1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 8560 |
DEGS1
DEGS DEGS-1 DES1 Des-1 FADS7 MLD |
delta(4)-desaturase, sphingolipid 1 (EC:1.14.-.-) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DEGS1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 1734 |
DIO2
5DII D2 DIOII SelY TXDI2 |
deiodinase, iodothyronine, type II (EC:1.97.1.10) | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased activity of DIO2 protein] |
decreases activity
/ decreases reaction |
protein |
11425850
|
D003513 | 1734 |
DIO2
5DII D2 DIOII SelY TXDI2 |
deiodinase, iodothyronine, type II (EC:1.97.1.10) | Cycloheximide results in decreased activity of DIO2 protein |
decreases activity
|
protein |
11425850
|
D003513 | 1734 |
DIO2
5DII D2 DIOII SelY TXDI2 |
deiodinase, iodothyronine, type II (EC:1.97.1.10) | lactacystin inhibits the reaction [Cycloheximide results in decreased activity of DIO2 protein] |
decreases activity
/ decreases reaction |
protein |
11425850
|
D003513 | 8847 |
DLEU2
1B4 BCMSUN DLB2 LEU2 LINC00022 MIR15AHG NCRNA00022 RFP2OS TRIM13OS |
deleted in lymphocytic leukemia 2 (non-protein coding) | [Cycloheximide co-treated with Estradiol] results in increased expression of DLEU2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
15072547
|
D003513 | 8847 |
DLEU2
1B4 BCMSUN DLB2 LEU2 LINC00022 MIR15AHG NCRNA00022 RFP2OS TRIM13OS |
deleted in lymphocytic leukemia 2 (non-protein coding) | Cycloheximide results in increased expression of DLEU2 mRNA |
increases expression
|
mRNA |
15072547
|
D003513 | 25822 |
DNAJB5
Hsc40 |
DnaJ (Hsp40) homolog, subfamily B, member 5 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DNAJB5 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 10059 |
DNM1L
DLP1 DRP1 DVLP DYMPLE EMPF HDYNIV |
dynamin 1-like (EC:3.6.5.5) | Cycloheximide results in increased expression of DNM1L mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 10059 |
DNM1L
DLP1 DRP1 DVLP DYMPLE EMPF HDYNIV |
dynamin 1-like (EC:3.6.5.5) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of DNM1L mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 1956 |
EGFR
ERBB ERBB1 HER1 PIG61 mENA |
epidermal growth factor receptor (EC:2.7.10.1) | Cycloheximide results in increased expression of EGFR mRNA |
increases expression
|
mRNA |
15228094
|
D003513 | 1958 |
EGR1
AT225 G0S30 KROX-24 NGFI-A TIS8 ZIF-268 ZNF225 |
early growth response 1 | Cycloheximide inhibits the reaction [resveratrol results in increased expression of EGR1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
12690110
|
D003513 | 1959 |
EGR2
AT591 CMT1D CMT4E KROX20 |
early growth response 2 | Cycloheximide results in increased expression of EGR2 mRNA |
increases expression
|
mRNA |
19350554
|
D003513 | 83939 |
EIF2A
EIF-2A MST089 MSTP004 MSTP089 |
eukaryotic translation initiation factor 2A, 65kDa | Cycloheximide inhibits the reaction [orlistat results in increased phosphorylation of EIF2A protein] |
decreases reaction
/ increases phosphorylation |
protein |
17283163
|
D003513 | 1965 |
EIF2S1
EIF-2 EIF-2A EIF-2alpha EIF2 EIF2A |
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | Cycloheximide results in increased expression of EIF2S1 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 1965 |
EIF2S1
EIF-2 EIF-2A EIF-2alpha EIF2 EIF2A |
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of EIF2S1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 8672 |
EIF4G3
eIF-4G_3 eIF4G_3 eIF4GII |
eukaryotic translation initiation factor 4 gamma, 3 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of EIF4G3 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 1983 |
EIF5
EIF-5 EIF-5A |
eukaryotic translation initiation factor 5 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of EIF5 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
19684285
|
D003513 | 2000 |
ELF4
ELFR MEF |
E74-like factor 4 (ets domain transcription factor) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ELF4 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 2002 |
ELK1
|
ELK1, member of ETS oncogene family | Cycloheximide results in increased expression of ELK1 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 2002 |
ELK1
|
ELK1, member of ETS oncogene family | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ELK1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 8507 |
ENC1
CCL28 ENC-1 KLHL35 KLHL37 NRPB PIG10 TP53I10 |
ectodermal-neural cortex 1 (with BTB domain) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of ENC1 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
19684285
|
D003513 | 2021 |
ENDOG
|
endonuclease G | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ENDOG mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 1833 |
EPYC
DSPG3 PGLB Pg-Lb SLRR3B |
epiphycan | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of EPYC mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 2064 |
ERBB2
CD340 HER-2 HER-2/neu HER2 MLN_19 NEU NGL TKR1 |
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) | [Cycloheximide co-treated with Estradiol] results in decreased expression of ERBB2 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
15072547
|
D003513 | 2064 |
ERBB2
CD340 HER-2 HER-2/neu HER2 MLN_19 NEU NGL TKR1 |
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) | Cycloheximide results in decreased expression of ERBB2 mRNA |
decreases expression
|
mRNA |
15072547
15228094 |
D003513 | 2064 |
ERBB2
CD340 HER-2 HER-2/neu HER2 MLN_19 NEU NGL TKR1 |
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) | Cycloheximide results in decreased expression of ERBB2 protein |
decreases expression
|
protein |
20379846
|
D003513 | 2064 |
ERBB2
CD340 HER-2 HER-2/neu HER2 MLN_19 NEU NGL TKR1 |
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) | PA2G4 protein promotes the reaction [Cycloheximide results in decreased expression of ERBB2 protein] |
decreases expression
/ increases reaction |
protein |
20379846
|
D003513 | 2065 |
ERBB3
ErbB-3 HER3 LCCS2 MDA-BF-1 c-erbB-3 c-erbB3 erbB3-S p180-ErbB3 p45-sErbB3 p85-sErbB3 |
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (EC:2.7.10.1) | Cycloheximide results in decreased expression of ERBB3 mRNA |
decreases expression
|
mRNA |
15228094
|
D003513 | 2069 |
EREG
ER |
epiregulin | Cycloheximide results in increased expression of EREG mRNA |
increases expression
|
mRNA |
15228094
|
D003513 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Cycloheximide promotes the reaction [Estradiol results in increased expression of ESR2 mRNA] |
increases expression
/ increases reaction |
mRNA |
15207704
|
D003513 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | Tetrachlorodibenzodioxin inhibits the reaction [Cycloheximide promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]] |
decreases reaction
/ increases expression / increases reaction |
mRNA |
15207704
|
D003513 | 2132 |
EXT2
SOTV |
exostosin glycosyltransferase 2 (EC:2.4.1.225 2.4.1.224) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of EXT2 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 2161 |
F12
HAE3 HAEX HAF |
coagulation factor XII (Hageman factor) (EC:3.4.21.38) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of F12 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 2147 |
F2
PT RPRGL2 THPH1 |
coagulation factor II (thrombin) (EC:3.4.21.5) | Cycloheximide inhibits the reaction [Simvastatin results in decreased activity of F2 protein] |
decreases activity
/ decreases reaction |
protein |
14630613
|
D003513 | 355 |
FAS
ALPS1A APO-1 APT1 CD95 FAS1 FASTM TNFRSF6 |
Fas cell surface death receptor | Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP3 protein] |
increases activity
/ increases reaction |
protein |
12760867
|
D003513 | 355 |
FAS
ALPS1A APO-1 APT1 CD95 FAS1 FASTM TNFRSF6 |
Fas cell surface death receptor | Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP7 protein] |
increases activity
/ increases reaction |
protein |
12760867
|
D003513 | 355 |
FAS
ALPS1A APO-1 APT1 CD95 FAS1 FASTM TNFRSF6 |
Fas cell surface death receptor | Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP8 protein] |
increases activity
/ increases reaction |
protein |
12760867
|
D003513 | 356 |
FASLG
ALPS1B APT1LG1 APTL CD178 CD95-L CD95L FASL TNFSF6 |
Fas ligand (TNF superfamily, member 6) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FASLG mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 2194 |
FASN
FAS OA-519 SDR27X1 |
fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39) | Cycloheximide inhibits the reaction [Calcitriol results in decreased expression of FASN mRNA] |
decreases expression
/ decreases reaction |
mRNA |
12798352
|
D003513 | 2091 |
FBL
FIB FLRN RNU3IP1 |
fibrillarin | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of FBL mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 10875 |
FGL2
T49 pT49 |
fibrinogen-like 2 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FGL2 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 2272 |
FHIT
AP3Aase FRA3B |
fragile histidine triad (EC:3.6.1.29) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of FHIT mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 2277 |
FIGF
VEGF-D VEGFD |
c-fos induced growth factor (vascular endothelial growth factor D) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FIGF mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 2332 |
FMR1
FMRP FRAXA POF POF1 |
fragile X mental retardation 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of FMR1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 2353 |
FOS
AP-1 C-FOS p55 |
FBJ murine osteosarcoma viral oncogene homolog | Cycloheximide inhibits the reaction [Estradiol results in increased expression of FOS protein] |
decreases reaction
/ increases expression |
protein |
15090535
|
D003513 | 2353 |
FOS
AP-1 C-FOS p55 |
FBJ murine osteosarcoma viral oncogene homolog | Cycloheximide inhibits the reaction [Genistein results in increased expression of FOS protein] |
decreases reaction
/ increases expression |
protein |
15090535
|
D003513 | 2353 |
FOS
AP-1 C-FOS p55 |
FBJ murine osteosarcoma viral oncogene homolog | Cycloheximide inhibits the reaction [Quercetin results in increased expression of FOS protein] |
decreases reaction
/ increases expression |
protein |
15090535
|
D003513 | 2444 |
FRK
GTK PTK5 RAK |
fyn-related kinase (EC:2.7.10.2) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FRK mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 10468 |
FST
FS |
follistatin | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FST mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 2526 |
FUT4
CD15 ELFT FCT3A FUC-TIV FUTIV LeX SSEA-1 |
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) (EC:2.4.1.-) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FUT4 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 8324 |
FZD7
FzE3 |
frizzled family receptor 7 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FZD7 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 2589 |
GALNT1
GALNAC-T1 |
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) (EC:2.4.1.41) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of GALNT1 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
19684285
|
D003513 | 2619 |
GAS1
|
growth arrest-specific 1 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GAS1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 9518 |
GDF15
GDF-15 MIC-1 MIC1 NAG-1 PLAB PTGFB |
growth differentiation factor 15 | Cycloheximide inhibits the reaction [trichostatin A affects the expression of GDF15 mRNA] |
affects expression
/ decreases reaction |
mRNA |
18801729
|
D003513 | 9518 |
GDF15
GDF-15 MIC-1 MIC1 NAG-1 PLAB PTGFB |
growth differentiation factor 15 | Cycloheximide inhibits the reaction [trichostatin A affects the expression of GDF15 protein] |
affects expression
/ decreases reaction |
protein |
18801729
|
D003513 | 9518 |
GDF15
GDF-15 MIC-1 MIC1 NAG-1 PLAB PTGFB |
growth differentiation factor 15 | Cycloheximide inhibits the reaction [troglitazone results in increased expression of GDF15 mRNA] |
decreases reaction
/ increases expression |
mRNA |
14662774
|
D003513 | 8733 |
GPAA1
GAA1 hGAA1 |
glycosylphosphatidylinositol anchor attachment 1 | Cycloheximide results in increased expression of GPAA1 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 8733 |
GPAA1
GAA1 hGAA1 |
glycosylphosphatidylinositol anchor attachment 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of GPAA1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 2861 |
GPR37
EDNRBL PAELR hET(B)R-LP |
G protein-coupled receptor 37 (endothelin receptor type B-like) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GPR37 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 2896 |
GRN
CLN11 GEP GP88 PCDGF PEPI PGRN |
granulin | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of GRN mRNA |
affects cotreatment
/ decreases expression |
mRNA |
19684285
|
D003513 | 2932 |
GSK3B
|
glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GSK3B mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 1839 |
HBEGF
DTR DTS DTSF HEGFL |
heparin-binding EGF-like growth factor | Cycloheximide results in increased expression of HBEGF mRNA |
increases expression
|
mRNA |
15228094
|
D003513 | 3091 |
HIF1A
HIF-1A HIF-1alpha HIF1 HIF1-ALPHA MOP1 PASD8 bHLHe78 |
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Cycloheximide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein] |
decreases reaction
/ increases expression |
protein |
20524035
|
D003513 | 3091 |
HIF1A
HIF-1A HIF-1alpha HIF1 HIF1-ALPHA MOP1 PASD8 bHLHe78 |
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Cycloheximide inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein] |
decreases reaction
/ increases expression |
protein |
11641398
|
D003513 | 3091 |
HIF1A
HIF-1A HIF-1alpha HIF1 HIF1-ALPHA MOP1 PASD8 bHLHe78 |
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Cycloheximide inhibits the reaction [zinc chloride results in increased expression of HIF1A protein alternative form] |
decreases reaction
/ increases expression |
protein |
11739637
|
D003513 | 3091 |
HIF1A
HIF-1A HIF-1alpha HIF1 HIF1-ALPHA MOP1 PASD8 bHLHe78 |
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Cycloheximide results in increased degradation of HIF1A protein |
increases degradation
|
protein |
11641398
|
D003513 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Cycloheximide inhibits the reaction [Curcumin results in increased expression of HMOX1 protein] |
decreases reaction
/ increases expression |
protein |
18357586
|
D003513 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Cycloheximide inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
19781563
|
D003513 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Cycloheximide inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein] |
decreases reaction
/ increases expression |
protein |
19781563
|
D003513 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Cycloheximide inhibits the reaction [Plant Extracts results in increased expression of HMOX1 protein] |
decreases reaction
/ increases expression |
protein |
21840424
|
D003513 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Cycloheximide inhibits the reaction [resveratrol results in increased expression of HMOX1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15588712
|
D003513 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Cycloheximide inhibits the reaction [resveratrol results in increased expression of HMOX1 protein] |
decreases reaction
/ increases expression |
protein |
15588712
|
D003513 | 3162 |
HMOX1
HMOX1D HO-1 HSP32 bK286B10 |
heme oxygenase (decycling) 1 (EC:1.14.99.3) | Cycloheximide results in decreased susceptibility to [surfactin peptide results in increased expression of HMOX1 protein] |
decreases response to substance
/ increases expression |
protein |
20833156
|
D003513 | 3188 |
HNRNPH2
FTP3 HNRPH' HNRPH2 hnRNPH' |
heterogeneous nuclear ribonucleoprotein H2 (H') | Cycloheximide results in increased expression of HNRNPH2 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 10553 |
HTATIP2
CC3 SDR44U1 TIP30 |
HIV-1 Tat interactive protein 2, 30kDa (EC:1.1.1.-) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of HTATIP2 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 3383 |
ICAM1
BB2 CD54 P3.58 |
intercellular adhesion molecule 1 | Cycloheximide inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein] |
decreases reaction
/ increases expression |
protein |
16087364
|
D003513 | 3383 |
ICAM1
BB2 CD54 P3.58 |
intercellular adhesion molecule 1 | Cycloheximide results in decreased expression of ICAM1 protein |
decreases expression
|
protein |
16087364
|
D003513 | 8870 |
IER3
DIF-2 DIF2 GLY96 IEX-1 IEX-1L IEX1 PRG1 |
immediate early response 3 | [hydroxytamoxifen co-treated with Cycloheximide] results in increased expression of IER3 mRNA |
affects cotreatment
/ increases expression |
mRNA |
16849584
|
D003513 | 2537 |
IFI6
6-16 FAM14C G1P3 IFI-6-16 IFI616 |
interferon, alpha-inducible protein 6 | IFI6 protein inhibits the reaction [Cycloheximide results in increased activity of CASP3 protein] |
decreases reaction
/ increases activity |
protein |
15685448
|
D003513 | 3440 |
IFNA2
IFN-alphaA IFNA IFNA2B INFA2 |
interferon, alpha 2 | [Cycloheximide co-treated with IFNA2 protein] results in increased expression of PLAUR mRNA |
affects cotreatment
/ increases expression |
protein |
12070711
|
D003513 | 3458 |
IFNG
IFG IFI |
interferon, gamma | [Cycloheximide co-treated with IFNG protein] results in increased expression of PLAUR mRNA |
affects cotreatment
/ increases expression |
protein |
12070711
|
D003513 | 3458 |
IFNG
IFG IFI |
interferon, gamma | Cycloheximide inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein] |
decreases reaction
/ increases expression |
protein |
16087364
|
D003513 | 3458 |
IFNG
IFG IFI |
interferon, gamma | Cycloheximide inhibits the reaction [IFNG protein results in increased expression of TJP1 protein] |
decreases reaction
/ increases expression |
protein |
16087364
|
D003513 | 11020 |
IFT27
RABL4 RAYL |
intraflagellar transport 27 homolog (Chlamydomonas) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of IFT27 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 3487 |
IGFBP4
BP-4 HT29-IGFBP IBP4 IGFBP-4 |
insulin-like growth factor binding protein 4 | [Cycloheximide co-treated with Estradiol] results in increased expression of IGFBP4 mRNA |
affects cotreatment
/ increases expression |
mRNA |
15072547
|
D003513 | 3487 |
IGFBP4
BP-4 HT29-IGFBP IBP4 IGFBP-4 |
insulin-like growth factor binding protein 4 | Cycloheximide results in increased expression of IGFBP4 mRNA |
increases expression
|
mRNA |
15072547
|
D003513 | 3552 |
IL1A
IL-1A IL1 IL1-ALPHA IL1F1 |
interleukin 1, alpha | Cycloheximide results in increased expression of IL1A mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 3552 |
IL1A
IL-1A IL1 IL1-ALPHA IL1F1 |
interleukin 1, alpha | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of IL1A mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | Cycloheximide inhibits the reaction [Dinoprostone promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]] |
decreases reaction
/ increases expression / increases reaction |
protein |
11112151
|
D003513 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | Cycloheximide inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] |
decreases reaction
/ increases expression |
protein |
11112151
|
D003513 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | Cycloheximide inhibits the reaction [IL1B results in increased secretion of CSF2 protein] |
decreases reaction
/ increases secretion |
9606035
|
|
D003513 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | Cycloheximide inhibits the reaction [IL8 protein affects the secretion of IL1B protein] |
affects secretion
/ decreases reaction |
protein |
8071060
|
D003513 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | Cycloheximide results in increased expression of IL1B mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 3553 |
IL1B
IL-1 IL1-BETA IL1F2 |
interleukin 1, beta | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of IL1B mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 3569 |
IL6
BSF2 HGF HSF IFNB2 IL-6 |
interleukin 6 (interferon, beta 2) | Cycloheximide inhibits the reaction [IL8 protein affects the secretion of IL6 protein] |
affects secretion
/ decreases reaction |
protein |
8071060
|
D003513 | 3569 |
IL6
BSF2 HGF HSF IFNB2 IL-6 |
interleukin 6 (interferon, beta 2) | Cycloheximide results in decreased secretion of IL6 protein |
decreases secretion
|
protein |
11216681
|
D003513 | 3569 |
IL6
BSF2 HGF HSF IFNB2 IL-6 |
interleukin 6 (interferon, beta 2) | Cycloheximide results in increased expression of IL6 mRNA |
increases expression
|
mRNA |
21146893
|
D003513 | 3569 |
IL6
BSF2 HGF HSF IFNB2 IL-6 |
interleukin 6 (interferon, beta 2) | Cycloheximide results in increased secretion of IL6 protein |
increases secretion
|
protein |
21146893
|
D003513 | 3569 |
IL6
BSF2 HGF HSF IFNB2 IL-6 |
interleukin 6 (interferon, beta 2) | TNF protein promotes the reaction [Cycloheximide results in increased expression of IL6 mRNA] |
increases expression
/ increases reaction |
mRNA |
21146893
|
D003513 | 3569 |
IL6
BSF2 HGF HSF IFNB2 IL-6 |
interleukin 6 (interferon, beta 2) | TNF protein promotes the reaction [Cycloheximide results in increased secretion of IL6 protein] |
increases reaction
/ increases secretion |
protein |
21146893
|
D003513 | 3569 |
IL6
BSF2 HGF HSF IFNB2 IL-6 |
interleukin 6 (interferon, beta 2) | Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of IL6 mRNA]] |
decreases reaction
/ increases expression / increases reaction |
mRNA |
21146893
|
D003513 | 3569 |
IL6
BSF2 HGF HSF IFNB2 IL-6 |
interleukin 6 (interferon, beta 2) | Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased secretion of IL6 protein]] |
decreases reaction
/ increases reaction / increases secretion |
protein |
21146893
|
D003513 | 3572 |
IL6ST
CD130 CDW130 GP130 IL-6RB |
interleukin 6 signal transducer (gp130, oncostatin M receptor) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL6ST mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Cycloheximide inhibits the reaction [cadmium sulfate results in increased secretion of IL8 protein] |
decreases reaction
/ increases secretion |
protein |
22094458
|
D003513 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Cycloheximide inhibits the reaction [deoxynivalenol results in increased expression of IL8 protein] |
decreases reaction
/ increases expression |
protein |
18308354
|
D003513 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Cycloheximide inhibits the reaction [IL8 protein affects the secretion of IL1B protein] |
affects secretion
/ decreases reaction |
protein |
8071060
|
D003513 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Cycloheximide inhibits the reaction [IL8 protein affects the secretion of IL6 protein] |
affects secretion
/ decreases reaction |
protein |
8071060
|
D003513 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Cycloheximide inhibits the reaction [IL8 protein affects the secretion of TNF protein] |
affects secretion
/ decreases reaction |
protein |
8071060
|
D003513 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Cycloheximide inhibits the reaction [IL8 protein results in increased expression of CCND1 protein] |
decreases reaction
/ increases expression |
protein |
17606477
|
D003513 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Zinc deficiency results in decreased expression of IL8 protein]] |
decreases expression
/ decreases reaction |
protein |
12812920
|
D003513 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL8 protein] |
decreases reaction
/ increases expression |
protein |
12812920
|
D003513 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Cycloheximide results in increased expression of IL8 mRNA |
increases expression
|
mRNA |
21146893
|
D003513 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | [TNF protein co-treated with Cycloheximide] results in increased secretion of IL8 protein |
affects cotreatment
/ increases secretion |
protein |
21146893
|
D003513 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | TNF protein promotes the reaction [Cycloheximide results in increased expression of IL8 mRNA] |
increases expression
/ increases reaction |
mRNA |
21146893
|
D003513 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Ursodeoxycholic Acid analog inhibits the reaction [[TNF protein co-treated with Cycloheximide] results in increased secretion of IL8 protein] |
affects cotreatment
/ decreases reaction / increases secretion |
protein |
21146893
|
D003513 | 3576 |
IL8
CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 |
interleukin 8 | Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of IL8 mRNA]] |
decreases reaction
/ increases expression / increases reaction |
mRNA |
21146893
|
D003513 | 8826 |
IQGAP1
HUMORFA01 SAR1 p195 |
IQ motif containing GTPase activating protein 1 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IQGAP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 3667 |
IRS1
HIRS-1 |
insulin receptor substrate 1 | [Cycloheximide co-treated with Estradiol] results in increased expression of IRS1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
15072547
|
D003513 | 3667 |
IRS1
HIRS-1 |
insulin receptor substrate 1 | Cycloheximide results in decreased expression of IRS1 mRNA |
decreases expression
|
mRNA |
15072547
|
D003513 | 3690 |
ITGB3
BDPLT16 BDPLT2 CD61 GP3A GPIIIa GT |
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ITGB3 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 3694 |
ITGB6
|
integrin, beta 6 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ITGB6 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 3694 |
ITGB6
|
integrin, beta 6 | Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of ITGB6 mRNA] |
decreases reaction
/ increases expression |
mRNA |
21303922
|
D003513 | 3705 |
ITPK1
ITRPK1 |
inositol-tetrakisphosphate 1-kinase (EC:2.7.1.134 2.7.1.159) | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein] |
affects cotreatment
/ decreases reaction / increases activity |
12925536
|
|
D003513 | 3705 |
ITPK1
ITRPK1 |
inositol-tetrakisphosphate 1-kinase (EC:2.7.1.134 2.7.1.159) | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein] |
affects cotreatment
/ decreases reaction / increases activity / increases cleavage |
12925536
|
|
D003513 | 3705 |
ITPK1
ITRPK1 |
inositol-tetrakisphosphate 1-kinase (EC:2.7.1.134 2.7.1.159) | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein] |
affects cotreatment
/ decreases reaction / increases activity / increases cleavage |
12925536
|
|
D003513 | 3705 |
ITPK1
ITRPK1 |
inositol-tetrakisphosphate 1-kinase (EC:2.7.1.134 2.7.1.159) | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of BID protein] |
affects cotreatment
/ decreases reaction / increases cleavage |
12925536
|
|
D003513 | 3705 |
ITPK1
ITRPK1 |
inositol-tetrakisphosphate 1-kinase (EC:2.7.1.134 2.7.1.159) | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of PARP1 protein] |
affects cotreatment
/ decreases reaction / increases cleavage |
12925536
|
|
D003513 | 3705 |
ITPK1
ITRPK1 |
inositol-tetrakisphosphate 1-kinase (EC:2.7.1.134 2.7.1.159) | ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of BID protein] |
affects cotreatment
/ increases cleavage / increases reaction |
mutant form |
12925536
|
D003513 | 3705 |
ITPK1
ITRPK1 |
inositol-tetrakisphosphate 1-kinase (EC:2.7.1.134 2.7.1.159) | ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein] |
affects cotreatment
/ increases cleavage / increases reaction |
mutant form |
12925536
|
D003513 | 3705 |
ITPK1
ITRPK1 |
inositol-tetrakisphosphate 1-kinase (EC:2.7.1.134 2.7.1.159) | ITPK1 mutant form results in increased susceptibility to [Cycloheximide co-treated with TNF protein] |
affects cotreatment
/ increases response to substance |
mutant form |
12925536
|
D003513 | 3708 |
ITPR1
INSP3R1 IP3R IP3R1 SCA15 SCA16 SCA29 |
inositol 1,4,5-trisphosphate receptor, type 1 | Cycloheximide inhibits the reaction [Ethanol results in increased expression of ITPR1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
17241155
|
D003513 | 3708 |
ITPR1
INSP3R1 IP3R IP3R1 SCA15 SCA16 SCA29 |
inositol 1,4,5-trisphosphate receptor, type 1 | Cycloheximide inhibits the reaction [linsidomine results in increased expression of ITPR1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
17241155
|
D003513 | 3708 |
ITPR1
INSP3R1 IP3R IP3R1 SCA15 SCA16 SCA29 |
inositol 1,4,5-trisphosphate receptor, type 1 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ITPR1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 23189 |
KANK1
ANKRD15 CPSQ2 KANK |
KN motif and ankyrin repeat domains 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of KANK1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 23313 |
C22orf9
|
KIAA0930 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of KIAA0930 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 3845 |
KRAS
C-K-RAS CFC2 K-RAS2A K-RAS2B K-RAS4A K-RAS4B KI-RAS KRAS1 KRAS2 NS NS3 RASK2 |
Kirsten rat sarcoma viral oncogene homolog | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of KRAS mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 3860 |
KRT13
CK13 K13 |
keratin 13 | [hydroxytamoxifen co-treated with Cycloheximide] results in increased expression of KRT13 mRNA |
affects cotreatment
/ increases expression |
mRNA |
16849584
|
D003513 | 200185 |
KRTCAP2
KCP2 |
keratinocyte associated protein 2 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of KRTCAP2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 3932 |
LCK
LSK YT16 p56lck pp58lck |
lymphocyte-specific protein tyrosine kinase (EC:2.7.10.2) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of LCK mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 3958 |
LGALS3
CBP35 GAL3 GALBP GALIG L31 LGALS2 MAC2 |
lectin, galactoside-binding, soluble, 3 | Cycloheximide inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of LGALS3 protein] |
decreases reaction
/ increases expression |
protein |
21821001
|
D003513 | 4008 |
LMO7
FBX20 FBXO20 LOMP |
LIM domain 7 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of LMO7 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 9404 |
LPXN
LDPL |
leupaxin | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of LPXN mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | Cycloheximide results in increased phosphorylation of MAPK1 protein |
increases phosphorylation
|
protein |
15087236
|
D003513 | 5594 |
MAPK1
ERK ERK2 ERT1 MAPK2 P42MAPK PRKM1 PRKM2 p38 p40 p41 p41mapk |
mitogen-activated protein kinase 1 (EC:2.7.11.24) | TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK1 protein] |
affects reaction
/ increases phosphorylation |
protein |
15087236
|
D003513 | 1432 |
MAPK14
CSBP CSBP1 CSBP2 CSPB1 EXIP Mxi2 PRKM14 PRKM15 RK SAPK2A p38 p38ALPHA |
mitogen-activated protein kinase 14 (EC:2.7.11.24) | Cycloheximide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein] |
decreases phosphorylation
/ decreases reaction |
protein |
17507666
|
D003513 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | Cycloheximide results in increased phosphorylation of MAPK3 protein |
increases phosphorylation
|
protein |
15087236
|
D003513 | 5595 |
MAPK3
ERK-1 ERK1 ERT2 HS44KDAP HUMKER1A P44ERK1 P44MAPK PRKM3 p44-ERK1 p44-MAPK |
mitogen-activated protein kinase 3 (EC:2.7.11.24) | TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK3 protein] |
affects reaction
/ increases phosphorylation |
protein |
15087236
|
D003513 | 5598 |
MAPK7
BMK1 ERK4 ERK5 PRKM7 |
mitogen-activated protein kinase 7 (EC:2.7.11.24) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MAPK7 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 5598 |
MAPK7
BMK1 ERK4 ERK5 PRKM7 |
mitogen-activated protein kinase 7 (EC:2.7.11.24) | Cycloheximide results in increased expression of MAPK7 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 5598 |
MAPK7
BMK1 ERK4 ERK5 PRKM7 |
mitogen-activated protein kinase 7 (EC:2.7.11.24) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MAPK7 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 4170 |
MCL1
BCL2L3 EAT MCL1-ES MCL1L MCL1S Mcl-1 TM bcl2-L-3 mcl1/EAT |
myeloid cell leukemia sequence 1 (BCL2-related) | [Cycloheximide co-treated with MCL1] results in increased susceptibility to ABT-737 |
affects cotreatment
/ increases response to substance |
21880625
|
|
D003513 | 4170 |
MCL1
BCL2L3 EAT MCL1-ES MCL1L MCL1S Mcl-1 TM bcl2-L-3 mcl1/EAT |
myeloid cell leukemia sequence 1 (BCL2-related) | Cycloheximide results in decreased expression of MCL1 protein |
decreases expression
|
protein |
14982947
|
D003513 | 4192 |
MDK
ARAP MK NEGF2 |
midkine (neurite growth-promoting factor 2) | Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of MDK mRNA] |
decreases expression
/ increases reaction |
mRNA |
11007951
|
D003513 | 406991 |
MIR21
MIRN21 hsa-mir-21 miR-21 miRNA21 |
microRNA 21 | Cycloheximide inhibits the reaction [Dihydrotestosterone results in increased expression of MIR21 mRNA] |
decreases reaction
/ increases expression |
mRNA |
23052036
|
D003513 | 406991 |
MIR21
MIRN21 hsa-mir-21 miR-21 miRNA21 |
microRNA 21 | Cycloheximide inhibits the reaction [Estradiol results in decreased expression of MIR21 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
19264808
|
D003513 | 406991 |
MIR21
MIRN21 hsa-mir-21 miR-21 miRNA21 |
microRNA 21 | Cycloheximide inhibits the reaction [fludioxonil results in increased expression of MIR21 mRNA] |
decreases reaction
/ increases expression |
mRNA |
23052036
|
D003513 | 406991 |
MIR21
MIRN21 hsa-mir-21 miR-21 miRNA21 |
microRNA 21 | Cycloheximide inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR21 mRNA] |
decreases reaction
/ increases expression |
mRNA |
23052036
|
D003513 | 406991 |
MIR21
MIRN21 hsa-mir-21 miR-21 miRNA21 |
microRNA 21 | Cycloheximide results in increased expression of MIR21 mRNA |
increases expression
|
mRNA |
23052036
|
D003513 | 4312 |
MMP1
CLG CLGN |
matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) | Cycloheximide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein] |
decreases reaction
/ increases expression |
protein |
19136476
|
D003513 | 4312 |
MMP1
CLG CLGN |
matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15075337
|
D003513 | 4322 |
MMP13
CLG3 MANDP1 |
matrix metallopeptidase 13 (collagenase 3) (EC:3.4.24.-) | Cycloheximide results in increased expression of MMP13 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 4322 |
MMP13
CLG3 MANDP1 |
matrix metallopeptidase 13 (collagenase 3) (EC:3.4.24.-) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MMP13 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 3110 |
MNX1
HB9 HLXB9 HOXHB9 SCRA1 |
motor neuron and pancreas homeobox 1 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of MNX1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 4350 |
MPG
AAG ADPG APNG CRA36.1 MDG Mid1 PIG11 PIG16 anpg |
N-methylpurine-DNA glycosylase (EC:3.2.2.21) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MPG mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 51081 |
MRPS7
MRP-S MRP-S7 RP-S7 RPMS7 S7mt bMRP27a |
mitochondrial ribosomal protein S7 | Cycloheximide results in decreased expression of MRPS7 mRNA |
decreases expression
|
mRNA |
19684285
|
D003513 | 51081 |
MRPS7
MRP-S MRP-S7 RP-S7 RPMS7 S7mt bMRP27a |
mitochondrial ribosomal protein S7 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of MRPS7 mRNA |
affects cotreatment
/ affects expression |
mRNA |
19684285
|
D003513 | 4437 |
MSH3
DUP MRP1 |
mutS homolog 3 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of MSH3 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 4481 |
MSR1
CD204 SCARA1 SR-A SRA phSR1 phSR2 |
macrophage scavenger receptor 1 | Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
9614211
|
D003513 | 23788 |
MTCH2
MIMP SLC25A50 |
mitochondrial carrier 2 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MTCH2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 9108 |
MTMR7
|
myotubularin related protein 7 (EC:3.1.3.-) | Cycloheximide results in increased expression of MTMR7 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 9108 |
MTMR7
|
myotubularin related protein 7 (EC:3.1.3.-) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MTMR7 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 4084 |
MXD1
BHLHC58 MAD MAD1 |
MAX dimerization protein 1 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MXD1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 83463 |
MXD3
BHLHC13 MAD3 MYX |
MAX dimerization protein 3 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MXD3 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 4638 |
MYLK
AAT7 KRP MLCK MLCK1 MLCK108 MLCK210 MSTP083 MYLK1 smMLCK |
myosin light chain kinase (EC:2.7.11.18) | Cycloheximide inhibits the reaction [TNF protein results in increased expression of MYLK protein] |
decreases reaction
/ increases expression |
protein |
15701621
|
D003513 | 4077 |
NBR1
1A1-3B M17S2 |
neighbor of BRCA1 gene 1 | Cycloheximide results in increased expression of NBR1 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 4077 |
NBR1
1A1-3B M17S2 |
neighbor of BRCA1 gene 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of NBR1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 4751 |
NEK2
HsPK21 NEK2A NLK1 |
NIMA-related kinase 2 (EC:2.7.11.1) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NEK2 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 4780 |
NFE2L2
NRF2 |
nuclear factor, erythroid 2-like 2 | Cycloheximide inhibits the reaction [SB 203580 affects the reaction [Quercetin affects the localization of NFE2L2 protein]] |
affects localization
/ affects reaction / decreases reaction |
protein |
22197970
|
D003513 | 4780 |
NFE2L2
NRF2 |
nuclear factor, erythroid 2-like 2 | Cycloheximide inhibits the reaction [[SB 203580 co-treated with Quercetin] results in increased expression of NFE2L2 protein] |
affects cotreatment
/ decreases reaction / increases expression |
protein |
22197970
|
D003513 | 4780 |
NFE2L2
NRF2 |
nuclear factor, erythroid 2-like 2 | Cycloheximide inhibits the reaction [sulforafan results in increased expression of NFE2L2 protein] |
decreases reaction
/ increases expression |
protein |
22019695
|
D003513 | 4780 |
NFE2L2
NRF2 |
nuclear factor, erythroid 2-like 2 | [SB 203580 co-treated with Cycloheximide] inhibits the reaction [Quercetin results in decreased expression of NFE2L2 protein] |
affects cotreatment
/ decreases expression / decreases reaction |
protein |
22197970
|
D003513 | 4790 |
NFKB1
EBP-1 KBF1 NF-kB1 NF-kappa-B NF-kappaB NFKB-p105 NFKB-p50 NFkappaB p105 p50 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | Cycloheximide affects the localization of NFKB1 protein |
affects localization
|
protein |
16637064
|
D003513 | 4790 |
NFKB1
EBP-1 KBF1 NF-kB1 NF-kappa-B NF-kappaB NFKB-p105 NFKB-p50 NFkappaB p105 p50 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | Cycloheximide results in decreased expression of [NFKB1 protein binds to RELA protein] |
affects binding
/ decreases expression |
protein |
16637064
|
D003513 | 4790 |
NFKB1
EBP-1 KBF1 NF-kB1 NF-kappa-B NF-kappaB NFKB-p105 NFKB-p50 NFkappaB p105 p50 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | Cycloheximide results in increased expression of NFKB1 mRNA |
increases expression
|
mRNA |
21146893
|
D003513 | 4790 |
NFKB1
EBP-1 KBF1 NF-kB1 NF-kappa-B NF-kappaB NFKB-p105 NFKB-p50 NFkappaB p105 p50 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | TNF protein promotes the reaction [Cycloheximide results in increased expression of NFKB1 mRNA] |
increases expression
/ increases reaction |
mRNA |
21146893
|
D003513 | 4790 |
NFKB1
EBP-1 KBF1 NF-kB1 NF-kappa-B NF-kappaB NFKB-p105 NFKB-p50 NFkappaB p105 p50 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of NFKB1 mRNA]] |
decreases reaction
/ increases expression / increases reaction |
mRNA |
21146893
|
D003513 | 4792 |
NFKBIA
IKBA MAD-3 NFKBI |
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NFKBIA mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 4792 |
NFKBIA
IKBA MAD-3 NFKBI |
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NFKBIA protein] |
decreases expression
/ increases reaction |
protein |
15330761
|
D003513 | 4792 |
NFKBIA
IKBA MAD-3 NFKBI |
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] |
increases degradation
/ increases reaction |
protein |
15330761
|
D003513 | 4792 |
NFKBIA
IKBA MAD-3 NFKBI |
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | Cycloheximide results in decreased expression of NFKBIA protein |
decreases expression
|
protein |
15330761
16637064 21692457 |
D003513 | 4792 |
NFKBIA
IKBA MAD-3 NFKBI |
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | Cycloheximide results in increased degradation of NFKBIA protein |
increases degradation
|
protein |
15330761
|
D003513 | 4792 |
NFKBIA
IKBA MAD-3 NFKBI |
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | NFKBIA protein affects the reaction [Cycloheximide promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of SAT1 mRNA]] |
affects reaction
/ increases expression / increases reaction |
protein |
16637064
|
D003513 | 4792 |
NFKBIA
IKBA MAD-3 NFKBI |
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in decreased expression of NFKBIA protein] |
decreases expression
/ increases reaction |
protein |
15330761
|
D003513 | 4792 |
NFKBIA
IKBA MAD-3 NFKBI |
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in increased degradation of NFKBIA protein] |
increases degradation
/ increases reaction |
protein |
15330761
|
D003513 | 4843 |
NOS2
HEP-NOS INOS NOS NOS2A |
nitric oxide synthase 2, inducible (EC:1.14.13.39) | Cycloheximide inhibits the reaction [Cyclosporine results in increased expression of NOS2 protein] |
decreases reaction
/ increases expression |
protein |
10760090
|
D003513 | 4843 |
NOS2
HEP-NOS INOS NOS NOS2A |
nitric oxide synthase 2, inducible (EC:1.14.13.39) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NOS2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 4846 |
NOS3
ECNOS eNOS |
nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NOS3 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 4856 |
NOV
CCN3 IBP-9 IGFBP-9 IGFBP9 NOVh |
nephroblastoma overexpressed | [Cycloheximide co-treated with Estradiol] results in decreased expression of NOV mRNA |
affects cotreatment
/ decreases expression |
mRNA |
15072547
|
D003513 | 4856 |
NOV
CCN3 IBP-9 IGFBP-9 IGFBP9 NOVh |
nephroblastoma overexpressed | Cycloheximide results in increased expression of NOV mRNA |
increases expression
|
mRNA |
15072547
|
D003513 | 4886 |
NPY1R
NPY1-R NPYR |
neuropeptide Y receptor Y1 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NPY1R mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 10062 |
NR1H3
LXR-a LXRA RLD-1 |
nuclear receptor subfamily 1, group H, member 3 | Cycloheximide results in increased expression of NR1H3 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 10062 |
NR1H3
LXR-a LXRA RLD-1 |
nuclear receptor subfamily 1, group H, member 3 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of NR1H3 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 64710 |
NUCKS1
NUCKS |
nuclear casein kinase and cyclin-dependent kinase substrate 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of NUCKS1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 4986 |
OPRK1
K-OR-1 KOR KOR-1 OPRK |
opioid receptor, kappa 1 | Cycloheximide results in increased expression of OPRK1 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 4986 |
OPRK1
K-OR-1 KOR KOR-1 OPRK |
opioid receptor, kappa 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of OPRK1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 4988 |
OPRM1
LMOR M-OR-1 MOP MOR MOR1 OPRM |
opioid receptor, mu 1 | Cycloheximide inhibits the reaction [Dronabinol results in increased expression of OPRM1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
16434616
|
D003513 | 5036 |
PA2G4
EBP1 HG4-1 p38-2G4 |
proliferation-associated 2G4, 38kDa | PA2G4 protein promotes the reaction [Cycloheximide results in decreased expression of ERBB2 protein] |
decreases expression
/ increases reaction |
protein |
20379846
|
D003513 | 5069 |
PAPPA
ASBABP2 DIPLA1 IGFBP-4ase PAPA PAPP-A PAPPA1 |
pregnancy-associated plasma protein A, pappalysin 1 (EC:3.4.24.79) | Cycloheximide results in increased expression of PAPPA mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 5069 |
PAPPA
ASBABP2 DIPLA1 IGFBP-4ase PAPA PAPP-A PAPPA1 |
pregnancy-associated plasma protein A, pappalysin 1 (EC:3.4.24.79) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PAPPA mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 142 |
PARP1
ADPRT ADPRT_1 ADPRT1 ARTD1 PARP PARP-1 PPOL pADPRT-1 |
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) | [Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein |
affects cotreatment
/ increases cleavage |
protein |
12925536
|
D003513 | 142 |
PARP1
ADPRT ADPRT_1 ADPRT1 ARTD1 PARP PARP-1 PPOL pADPRT-1 |
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) | [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein |
affects cotreatment
/ increases cleavage |
protein |
18222423
|
D003513 | 142 |
PARP1
ADPRT ADPRT_1 ADPRT1 ARTD1 PARP PARP-1 PPOL pADPRT-1 |
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) | Cycloheximide results in increased cleavage of PARP1 protein |
increases cleavage
|
protein |
16051428
|
D003513 | 142 |
PARP1
ADPRT ADPRT_1 ADPRT1 ARTD1 PARP PARP-1 PPOL pADPRT-1 |
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of PARP1 protein] |
affects cotreatment
/ decreases reaction / increases cleavage |
protein |
12925536
|
D003513 | 142 |
PARP1
ADPRT ADPRT_1 ADPRT1 ARTD1 PARP PARP-1 PPOL pADPRT-1 |
poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) | ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein] |
affects cotreatment
/ increases cleavage / increases reaction |
protein |
12925536
|
D003513 | 5077 |
PAX3
CDHS HUP2 WS1 WS3 |
paired box 3 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PAX3 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 84759 |
PCGF1
2010002K04Rik NSPC1 RNF3A-2 RNF68 |
polycomb group ring finger 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PCGF1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 5111 |
PCNA
|
proliferating cell nuclear antigen | Cycloheximide inhibits the reaction [Vitamin K 3 results in decreased expression of PCNA protein] |
decreases expression
/ decreases reaction |
protein |
21533478
|
D003513 | 5134 |
PDCD2
RP8 ZMYND7 |
programmed cell death 2 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PDCD2 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 5297 |
PI4KA
PI4K-ALPHA PIK4CA pi4K230 |
phosphatidylinositol 4-kinase, catalytic, alpha (EC:2.7.1.67) | Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of PI4KA mRNA] |
decreases expression
/ increases reaction |
mRNA |
11007951
|
D003513 | 5283 |
PIGH
GPI-H |
phosphatidylinositol glycan anchor biosynthesis, class H (EC:2.4.1.198) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PIGH mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 10026 |
PIGK
GPI8 |
phosphatidylinositol glycan anchor biosynthesis, class K (EC:3.-.-.-) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PIGK mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 5289 |
PIK3C3
VPS34 hVps34 |
phosphatidylinositol 3-kinase, catalytic subunit type 3 (EC:2.7.1.137) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PIK3C3 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 5294 |
PIK3CG
PI3CG PI3K PI3Kgamma PIK3 p110gamma p120-PI3K |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (EC:2.7.11.1 2.7.1.153) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PIK3CG mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 29990 |
PILRB
FDFACT1 FDFACT2 |
paired immunoglobin-like type 2 receptor beta | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PILRB mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 5319 |
PLA2G1B
PLA2 PLA2A PPLA2 |
phospholipase A2, group IB (pancreas) (EC:3.1.1.4) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PLA2G1B mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 5329 |
PLAUR
CD87 U-PAR UPAR URKR |
plasminogen activator, urokinase receptor | [Cycloheximide co-treated with IFNA2 protein] results in increased expression of PLAUR mRNA |
affects cotreatment
/ increases expression |
mRNA |
12070711
|
D003513 | 5329 |
PLAUR
CD87 U-PAR UPAR URKR |
plasminogen activator, urokinase receptor | [Cycloheximide co-treated with IFNG protein] results in increased expression of PLAUR mRNA |
affects cotreatment
/ increases expression |
mRNA |
12070711
|
D003513 | 5329 |
PLAUR
CD87 U-PAR UPAR URKR |
plasminogen activator, urokinase receptor | Cycloheximide results in increased expression of PLAUR mRNA |
increases expression
|
mRNA |
12070711
|
D003513 | 23646 |
PLD3
HU-K4 HUK4 |
phospholipase D family, member 3 (EC:3.1.4.4) | Cycloheximide results in increased expression of PLD3 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 23646 |
PLD3
HU-K4 HUK4 |
phospholipase D family, member 3 (EC:3.1.4.4) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PLD3 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 5350 |
PLN
CMD1P CMH18 PLB |
phospholamban | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PLN mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 5366 |
PMAIP1
APR NOXA |
phorbol-12-myristate-13-acetate-induced protein 1 | Cycloheximide inhibits the reaction [Fenretinide results in increased expression of PMAIP1 protein] |
decreases reaction
/ increases expression |
protein |
17216584
|
D003513 | 5366 |
PMAIP1
APR NOXA |
phorbol-12-myristate-13-acetate-induced protein 1 | Cycloheximide inhibits the reaction [Thapsigargin results in increased expression of PMAIP1 protein] |
decreases reaction
/ increases expression |
protein |
17216584
|
D003513 | 10908 |
PNPLA6
NTE NTEMND SPG39 iPLA2delta sws |
patatin-like phospholipase domain containing 6 (EC:3.1.1.5) | Cycloheximide inhibits the reaction [Bucladesine results in increased activity of PNPLA6 protein] |
decreases reaction
/ increases activity |
protein |
20380879
|
D003513 | 10908 |
PNPLA6
NTE NTEMND SPG39 iPLA2delta sws |
patatin-like phospholipase domain containing 6 (EC:3.1.1.5) | Cycloheximide inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of PNPLA6 protein] |
affects cotreatment
/ decreases reaction / increases activity |
protein |
20380879
|
D003513 | 10908 |
PNPLA6
NTE NTEMND SPG39 iPLA2delta sws |
patatin-like phospholipase domain containing 6 (EC:3.1.1.5) | Cycloheximide inhibits the reaction [Colforsin results in increased activity of PNPLA6 protein] |
decreases reaction
/ increases activity |
protein |
20380879
|
D003513 | 56342 |
PPAN
BXDC3 SSF SSF-1 SSF1 SSF2 |
peter pan homolog (Drosophila) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PPAN mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 5532 |
PPP3CB
CALNA2 CALNB CNA2 PP2Bbeta |
protein phosphatase 3, catalytic subunit, beta isozyme (EC:3.1.3.16) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PPP3CB mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 10549 |
PRDX4
AOE37-2 PRX-4 |
peroxiredoxin 4 (EC:1.11.1.15) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PRDX4 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 5579 |
PRKCB
PKC-beta PKCB PRKCB1 PRKCB2 |
protein kinase C, beta (EC:2.7.11.13) | Cycloheximide results in decreased expression of PRKCB mRNA |
decreases expression
|
mRNA |
19684285
|
D003513 | 5579 |
PRKCB
PKC-beta PKCB PRKCB1 PRKCB2 |
protein kinase C, beta (EC:2.7.11.13) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PRKCB mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 5590 |
PRKCZ
PKC-ZETA PKC2 |
protein kinase C, zeta (EC:2.7.11.13) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PRKCZ mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 5728 |
PTEN
10q23del BZS CWS1 DEC GLM2 MHAM MMAC1 PTEN1 TEP1 |
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) | Cycloheximide inhibits the reaction [Lovastatin results in increased expression of PTEN protein] |
decreases reaction
/ increases expression |
protein |
16425225
|
D003513 | 5728 |
PTEN
10q23del BZS CWS1 DEC GLM2 MHAM MMAC1 PTEN1 TEP1 |
phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) | Cycloheximide inhibits the reaction [rosiglitazone results in increased expression of PTEN protein] |
decreases reaction
/ increases expression |
protein |
16425225
|
D003513 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Cycloheximide inhibits the reaction [Dinoprostone promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]] |
decreases reaction
/ increases expression / increases reaction |
protein |
11112151
|
D003513 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Cycloheximide inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] |
decreases reaction
/ increases expression |
protein |
11112151
|
D003513 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Cycloheximide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] |
decreases reaction
/ increases activity / increases expression |
protein |
7575673
|
D003513 | 5743 |
PTGS2
COX-2 COX2 GRIPGHS PGG/HS PGHS-2 PHS-2 hCox-2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | Cycloheximide inhibits the reaction [Tretinoin results in increased expression of PTGS2 protein] |
decreases reaction
/ increases expression |
protein |
16894348
|
D003513 | 5764 |
PTN
HARP HBGF8 HBNF NEGF1 |
pleiotrophin | Cycloheximide results in increased expression of PTN mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 5764 |
PTN
HARP HBGF8 HBNF NEGF1 |
pleiotrophin | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PTN mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 7803 |
PTP4A1
HH72 PRL-1 PRL1 PTP(CAAX1) PTPCAAX1 |
protein tyrosine phosphatase type IVA, member 1 (EC:3.1.3.48) | Cycloheximide inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Estradiol results in increased expression of PTP4A1 mRNA]] |
decreases reaction
/ increases expression |
mRNA |
19146866
|
D003513 | 7803 |
PTP4A1
HH72 PRL-1 PRL1 PTP(CAAX1) PTPCAAX1 |
protein tyrosine phosphatase type IVA, member 1 (EC:3.1.3.48) | Cycloheximide promotes the reaction [Estradiol results in increased expression of PTP4A1 mRNA] |
increases expression
/ increases reaction |
mRNA |
19146866
|
D003513 | 11156 |
PTP4A3
PRL-3 PRL-R PRL3 |
protein tyrosine phosphatase type IVA, member 3 (EC:3.1.3.48) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PTP4A3 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 2889 |
RAPGEF1
C3G GRF2 |
Rap guanine nucleotide exchange factor (GEF) 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of RAPGEF1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 5919 |
RARRES2
HP10433 TIG2 |
retinoic acid receptor responder (tazarotene induced) 2 | Cycloheximide results in increased expression of RARRES2 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 5919 |
RARRES2
HP10433 TIG2 |
retinoic acid receptor responder (tazarotene induced) 2 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of RARRES2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 5933 |
RBL1
CP107 PRB1 p107 |
retinoblastoma-like 1 (p107) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RBL1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 5970 |
RELA
NFKB3 p65 |
v-rel avian reticuloendotheliosis viral oncogene homolog A | Cycloheximide affects the localization of RELA protein |
affects localization
|
protein |
16637064
|
D003513 | 5970 |
RELA
NFKB3 p65 |
v-rel avian reticuloendotheliosis viral oncogene homolog A | [Cycloheximide co-treated with N(1),N(11)-diethylnorspermine] promotes the reaction [RELA protein binds to SAT1 promoter] |
affects binding
/ affects cotreatment / increases reaction |
protein |
16637064
|
D003513 | 5970 |
RELA
NFKB3 p65 |
v-rel avian reticuloendotheliosis viral oncogene homolog A | Cycloheximide promotes the reaction [RELA protein binds to SAT1 promoter] |
affects binding
/ increases reaction |
protein |
16637064
|
D003513 | 5970 |
RELA
NFKB3 p65 |
v-rel avian reticuloendotheliosis viral oncogene homolog A | Cycloheximide results in decreased expression of [NFKB1 protein binds to RELA protein] |
affects binding
/ decreases expression |
protein |
16637064
|
D003513 | 5972 |
REN
HNFJ2 |
renin (EC:3.4.23.15) | Cycloheximide inhibits the reaction [Dobutamine results in increased secretion of REN protein] |
decreases reaction
/ increases secretion |
protein |
9203624
|
D003513 | 5972 |
REN
HNFJ2 |
renin (EC:3.4.23.15) | Cycloheximide inhibits the reaction [Terbutaline results in increased secretion of REN protein] |
decreases reaction
/ increases secretion |
protein |
9203624
|
D003513 | 51065 |
RPS27L
|
ribosomal protein S27-like | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of RPS27L mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 6283 |
S100A12
CAAF1 CAGC CGRP ENRAGE MRP-6 MRP6 p6 |
S100 calcium binding protein A12 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of S100A12 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 6275 |
S100A4
18A2 42A CAPL FSP1 MTS1 P9KA PEL98 |
S100 calcium binding protein A4 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of S100A4 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 6278 |
S100A7
PSOR1 S100A7c |
S100 calcium binding protein A7 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of S100A7 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 6303 |
SAT1
DC21 KFSD KFSDX SAT SSAT SSAT-1 |
spermidine/spermine N1-acetyltransferase 1 (EC:2.3.1.57) | [Cycloheximide co-treated with N(1),N(11)-diethylnorspermine] promotes the reaction [RELA protein binds to SAT1 promoter] |
affects binding
/ affects cotreatment / increases reaction |
promoter |
16637064
|
D003513 | 6303 |
SAT1
DC21 KFSD KFSDX SAT SSAT SSAT-1 |
spermidine/spermine N1-acetyltransferase 1 (EC:2.3.1.57) | Cycloheximide promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of SAT1 mRNA] |
increases expression
/ increases reaction |
mRNA |
16637064
|
D003513 | 6303 |
SAT1
DC21 KFSD KFSDX SAT SSAT SSAT-1 |
spermidine/spermine N1-acetyltransferase 1 (EC:2.3.1.57) | Cycloheximide promotes the reaction [RELA protein binds to SAT1 promoter] |
affects binding
/ increases reaction |
promoter |
16637064
|
D003513 | 6303 |
SAT1
DC21 KFSD KFSDX SAT SSAT SSAT-1 |
spermidine/spermine N1-acetyltransferase 1 (EC:2.3.1.57) | NFKBIA protein affects the reaction [Cycloheximide promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of SAT1 mRNA]] |
affects reaction
/ increases expression / increases reaction |
mRNA |
16637064
|
D003513 | 90701 |
SEC11C
SEC11L3 SPC21 SPCS4C |
SEC11 homolog C (S. cerevisiae) (EC:3.4.21.89) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of SEC11C mRNA |
affects cotreatment
/ affects expression |
mRNA |
19684285
|
D003513 | 5272 |
SERPINB9
CAP-3 CAP3 PI-9 PI9 |
serpin peptidase inhibitor, clade B (ovalbumin), member 9 | Cycloheximide promotes the reaction [moxestrol results in increased expression of SERPINB9 mRNA] |
increases expression
/ increases reaction |
mRNA |
10681578
|
D003513 | 5054 |
SERPINE1
PAI PAI-1 PAI1 PLANH1 |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 5270 |
SERPINE2
GDN GDNPF PI-7 PI7 PN-1 PN1 PNI |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | Cycloheximide results in increased expression of SERPINE2 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 5270 |
SERPINE2
GDN GDNPF PI-7 PI7 PN-1 PN1 PNI |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SERPINE2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 9792 |
SERTAD2
Sei-2 TRIP-Br2 |
SERTA domain containing 2 | Cycloheximide results in increased expression of SERTAD2 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 9792 |
SERTAD2
Sei-2 TRIP-Br2 |
SERTA domain containing 2 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SERTAD2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 140885 |
SIRPA
BIT CD172A MFR MYD-1 P84 PTPNS1 SHPS1 SIRP |
signal-regulatory protein alpha (EC:3.1.3.48) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SIRPA mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 6503 |
SLA
SLA1 SLAP |
Src-like-adaptor | Cycloheximide inhibits the reaction [Tretinoin results in increased expression of SLA mRNA] |
decreases reaction
/ increases expression |
mRNA |
9020066
|
D003513 | 6566 |
SLC16A1
HHF7 MCT MCT1 |
solute carrier family 16 (monocarboxylate transporter), member 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC16A1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 6583 |
SLC22A4
OCTN1 |
solute carrier family 22 (organic cation/zwitterion transporter), member 4 | Cycloheximide results in increased expression of SLC22A4 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 6583 |
SLC22A4
OCTN1 |
solute carrier family 22 (organic cation/zwitterion transporter), member 4 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC22A4 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 9481 |
SLC25A27
UCP4 |
solute carrier family 25, member 27 | Cycloheximide results in increased expression of SLC25A27 mRNA |
increases expression
|
mRNA |
20385226
|
D003513 | 6513 |
SLC2A1
DYT17 DYT18 DYT9 EIG12 GLUT GLUT1 GLUT1DS HTLVR PED |
solute carrier family 2 (facilitated glucose transporter), member 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC2A1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 6528 |
SLC5A5
NIS TDH1 |
solute carrier family 5 (sodium/iodide cotransporter), member 5 | Cycloheximide results in increased expression of SLC5A5 mRNA |
increases expression
|
mRNA |
17164311
|
D003513 | 8140 |
SLC7A5
4F2LC CD98 D16S469E E16 LAT1 MPE16 hLAT1 |
solute carrier family 7 (amino acid transporter light chain, L system), member 5 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC7A5 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 57223 |
SMEK2
FLFL2 PP4R3B PSY2 smk1 |
SMEK homolog 2, suppressor of mek1 (Dictyostelium) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SMEK2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 6606 |
SMN1
BCD541 GEMIN1 SMA SMA1 SMA2 SMA3 SMA4 SMA@ SMN SMNT T-BCD541 TDRD16A |
survival of motor neuron 1, telomeric | Cycloheximide inhibits the reaction [Paraquat results in increased expression of SMN1 mRNA alternative form] |
decreases reaction
/ increases expression |
mRNA |
17064354
|
D003513 | 22938 |
SNW1
Bx42 NCOA-62 PRPF45 Prp45 SKIIP SKIP |
SNW domain containing 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SNW1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 8651 |
SOCS1
CIS1 CISH1 JAB SOCS-1 SSI-1 SSI1 TIP3 |
suppressor of cytokine signaling 1 | [hydroxytamoxifen co-treated with Cycloheximide] results in increased expression of SOCS1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
16849584
|
D003513 | 6648 |
SOD2
IPOB MNSOD MVCD6 |
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) | Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA] |
increases expression
/ increases reaction |
mRNA |
15330761
|
D003513 | 6648 |
SOD2
IPOB MNSOD MVCD6 |
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) | Cycloheximide results in increased expression of SOD2 mRNA |
increases expression
|
mRNA |
15330761
|
D003513 | 6648 |
SOD2
IPOB MNSOD MVCD6 |
superoxide dismutase 2, mitochondrial (EC:1.15.1.1) | Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in increased expression of SOD2 mRNA] |
increases expression
/ increases reaction |
mRNA |
15330761
|
D003513 | 6654 |
SOS1
GF1 GGF1 GINGF HGF NS4 |
son of sevenless homolog 1 (Drosophila) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SOS1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 6742 |
SSBP1
Mt-SSB SOSS-B1 SSBP mtSSB |
single-stranded DNA binding protein 1, mitochondrial | Cycloheximide results in increased expression of SSBP1 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 6742 |
SSBP1
Mt-SSB SOSS-B1 SSBP mtSSB |
single-stranded DNA binding protein 1, mitochondrial | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SSBP1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 6489 |
ST8SIA1
GD3S SIAT8 SIAT8-A SIAT8A ST8SiaI |
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 (EC:2.4.99.8) | Cycloheximide results in increased expression of ST8SIA1 mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 6489 |
ST8SIA1
GD3S SIAT8 SIAT8-A SIAT8A ST8SiaI |
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 (EC:2.4.99.8) | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ST8SIA1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 6788 |
STK3
KRS1 MST2 |
serine/threonine kinase 3 (EC:2.7.11.1) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of STK3 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 2054 |
STX2
EPIM EPM STX2A STX2B STX2C |
syntaxin 2 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of STX2 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 6817 |
SULT1A1
HAST1/HAST2 P-PST PST ST1A1 ST1A3 STP STP1 TSPST1 |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) | Cycloheximide inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
16308312
|
D003513 | 6820 |
SULT2B1
HSST2 |
sulfotransferase family, cytosolic, 2B, member 1 (EC:2.8.2.2) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SULT2B1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 6827 |
SUPT4H1
SPT4 SPT4H SUPT4H |
suppressor of Ty 4 homolog 1 (S. cerevisiae) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SUPT4H1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 11346 |
SYNPO
|
synaptopodin | Cycloheximide results in increased expression of SYNPO mRNA |
increases expression
|
mRNA |
19684285
|
D003513 | 11346 |
SYNPO
|
synaptopodin | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SYNPO mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 6867 |
TACC1
Ga55 |
transforming, acidic coiled-coil containing protein 1 | [Cycloheximide co-treated with Estradiol] results in decreased expression of TACC1 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
15072547
|
D003513 | 6867 |
TACC1
Ga55 |
transforming, acidic coiled-coil containing protein 1 | Cycloheximide results in increased expression of TACC1 mRNA |
increases expression
|
mRNA |
15072547
|
D003513 | 57252 | TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK1 protein] |
affects reaction
/ increases phosphorylation |
protein |
15087236
|
||
D003513 | 57252 | TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK3 protein] |
affects reaction
/ increases phosphorylation |
protein |
15087236
|
||
D003513 | 7031 |
TFF1
BCEI D21S21 HP1.A HPS2 pNR-2 pS2 |
trefoil factor 1 | [Cycloheximide co-treated with Estradiol] results in increased expression of TFF1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
15072547
|
D003513 | 7031 |
TFF1
BCEI D21S21 HP1.A HPS2 pNR-2 pS2 |
trefoil factor 1 | Cycloheximide inhibits the reaction [bisphenol A results in increased expression of TFF1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
20875696
|
D003513 | 7031 |
TFF1
BCEI D21S21 HP1.A HPS2 pNR-2 pS2 |
trefoil factor 1 | Cycloheximide results in increased expression of TFF1 mRNA |
increases expression
|
mRNA |
15072547
|
D003513 | 7039 |
TGFA
TFGA |
transforming growth factor, alpha | Cycloheximide results in increased expression of TGFA mRNA |
increases expression
|
mRNA |
15228094
|
D003513 | 7040 |
TGFB1
CED DPD1 LAP TGFB TGFbeta |
transforming growth factor, beta 1 | Cycloheximide inhibits the reaction [TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] |
decreases reaction
/ increases expression |
protein |
9145908
|
D003513 | 7040 |
TGFB1
CED DPD1 LAP TGFB TGFbeta |
transforming growth factor, beta 1 | Cycloheximide inhibits the reaction [TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]] |
decreases reaction
/ increases expression |
protein |
9145908
|
D003513 | 7040 |
TGFB1
CED DPD1 LAP TGFB TGFbeta |
transforming growth factor, beta 1 | Cycloheximide inhibits the reaction [TGFB1 protein results in decreased expression of AHR mRNA] |
decreases expression
/ decreases reaction |
protein |
9145908
|
D003513 | 7040 |
TGFB1
CED DPD1 LAP TGFB TGFbeta |
transforming growth factor, beta 1 | Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of ITGB6 mRNA] |
decreases reaction
/ increases expression |
protein |
21303922
|
D003513 | 7056 |
THBD
AHUS6 BDCA3 CD141 THPH12 THRM TM |
thrombomodulin | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of THBD mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 7070 |
THY1
CD90 |
Thy-1 cell surface antigen | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of THY1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 7082 |
TJP1
ZO-1 |
tight junction protein 1 | Cycloheximide inhibits the reaction [IFNG protein results in increased expression of TJP1 protein] |
decreases reaction
/ increases expression |
protein |
16087364
|
D003513 | 7082 |
TJP1
ZO-1 |
tight junction protein 1 | Cycloheximide results in decreased expression of TJP1 protein |
decreases expression
|
protein |
16087364
|
D003513 | 51768 |
TM7SF3
|
transmembrane 7 superfamily member 3 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of TM7SF3 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | [Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein |
affects cotreatment
/ increases cleavage |
protein |
12925536
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | [Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein |
affects cotreatment
/ increases activity |
12925536
|
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | [Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein |
affects cotreatment
/ increases activity / increases cleavage |
12925536
|
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | [Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein |
affects cotreatment
/ increases activity / increases cleavage |
12925536
|
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | [Cycloheximide co-treated with TNF] results in increased cleavage of BID protein |
affects cotreatment
/ increases cleavage |
12925536
|
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Cycloheximide inhibits the reaction [IL8 protein affects the secretion of TNF protein] |
affects secretion
/ decreases reaction |
protein |
8071060
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Cycloheximide inhibits the reaction [SM 164 results in increased expression of TNF mRNA] |
decreases reaction
/ increases expression |
mRNA |
22241084
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein] |
decreases reaction
/ increases expression |
protein |
12812920
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Cycloheximide inhibits the reaction [TNF protein results in increased expression of MYLK protein] |
decreases reaction
/ increases expression |
protein |
15701621
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Cycloheximide inhibits the reaction [Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]] |
decreases reaction
/ increases expression / increases reaction |
protein |
12812920
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein] |
affects cotreatment
/ decreases reaction / increases activity |
12925536
|
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein] |
affects cotreatment
/ decreases reaction / increases activity / increases cleavage |
12925536
|
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein] |
affects cotreatment
/ decreases reaction / increases activity / increases cleavage |
12925536
|
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of BID protein] |
affects cotreatment
/ decreases reaction / increases cleavage |
12925536
|
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of PARP1 protein] |
affects cotreatment
/ decreases reaction / increases cleavage |
12925536
|
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of BID protein] |
affects cotreatment
/ increases cleavage / increases reaction |
protein |
12925536
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein] |
affects cotreatment
/ increases cleavage / increases reaction |
protein |
12925536
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | ITPK1 mutant form results in increased susceptibility to [Cycloheximide co-treated with TNF protein] |
affects cotreatment
/ increases response to substance |
protein |
12925536
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | [TNF protein co-treated with Cycloheximide] results in increased expression of TNFAIP3 mRNA |
affects cotreatment
/ increases expression |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | [TNF protein co-treated with Cycloheximide] results in increased secretion of IL8 protein |
affects cotreatment
/ increases secretion |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL2 mRNA] |
increases expression
/ increases reaction |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL5 mRNA] |
increases expression
/ increases reaction |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | TNF protein promotes the reaction [Cycloheximide results in increased expression of IL6 mRNA] |
increases expression
/ increases reaction |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | TNF protein promotes the reaction [Cycloheximide results in increased expression of IL8 mRNA] |
increases expression
/ increases reaction |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | TNF protein promotes the reaction [Cycloheximide results in increased expression of NFKB1 mRNA] |
increases expression
/ increases reaction |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | TNF protein promotes the reaction [Cycloheximide results in increased secretion of IL6 protein] |
increases reaction
/ increases secretion |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | TNF protein results in increased susceptibility to Cycloheximide |
increases response to substance
|
protein |
16077199
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Ursodeoxycholic Acid analog inhibits the reaction [[TNF protein co-treated with Cycloheximide] results in increased secretion of IL8 protein] |
affects cotreatment
/ decreases reaction / increases secretion |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL2 mRNA]] |
decreases reaction
/ increases expression / increases reaction |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL5 mRNA]] |
decreases reaction
/ increases expression / increases reaction |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of IL6 mRNA]] |
decreases reaction
/ increases expression / increases reaction |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of IL8 mRNA]] |
decreases reaction
/ increases expression / increases reaction |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of NFKB1 mRNA]] |
decreases reaction
/ increases expression / increases reaction |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased secretion of IL6 protein]] |
decreases reaction
/ increases reaction / increases secretion |
protein |
21146893
|
D003513 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Ursodeoxycholic Acid analog promotes the reaction [[TNF protein co-treated with Cycloheximide] results in increased expression of TNFAIP3 mRNA] |
affects cotreatment
/ increases expression / increases reaction |
protein |
21146893
|
D003513 | 7128 |
TNFAIP3
A20 OTUD7C TNFA1P2 |
tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) | [TNF protein co-treated with Cycloheximide] results in increased expression of TNFAIP3 mRNA |
affects cotreatment
/ increases expression |
mRNA |
21146893
|
D003513 | 7128 |
TNFAIP3
A20 OTUD7C TNFA1P2 |
tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) | Ursodeoxycholic Acid analog promotes the reaction [[TNF protein co-treated with Cycloheximide] results in increased expression of TNFAIP3 mRNA] |
affects cotreatment
/ increases expression / increases reaction |
mRNA |
21146893
|
D003513 | 8797 |
TNFRSF10A
APO2 CD261 DR4 TRAILR-1 TRAILR1 |
tumor necrosis factor receptor superfamily, member 10a | Cycloheximide inhibits the reaction [docetaxel results in increased expression of TNFRSF10A protein] |
decreases reaction
/ increases expression |
protein |
11212279
|
D003513 | 8797 |
TNFRSF10A
APO2 CD261 DR4 TRAILR-1 TRAILR1 |
tumor necrosis factor receptor superfamily, member 10a | Cycloheximide inhibits the reaction [Paclitaxel results in increased expression of TNFRSF10A protein] |
decreases reaction
/ increases expression |
protein |
11212279
|
D003513 | 8795 |
TNFRSF10B
CD262 DR5 KILLER KILLER/DR5 TRAIL-R2 TRAILR2 TRICK2 TRICK2A TRICK2B TRICKB ZTNFR9 |
tumor necrosis factor receptor superfamily, member 10b | Cycloheximide inhibits the reaction [docetaxel results in increased expression of TNFRSF10B protein] |
decreases reaction
/ increases expression |
protein |
11212279
|
D003513 | 8795 |
TNFRSF10B
CD262 DR5 KILLER KILLER/DR5 TRAIL-R2 TRAILR2 TRICK2 TRICK2A TRICK2B TRICKB ZTNFR9 |
tumor necrosis factor receptor superfamily, member 10b | Cycloheximide inhibits the reaction [Paclitaxel results in increased expression of TNFRSF10B protein] |
decreases reaction
/ increases expression |
protein |
11212279
|
D003513 | 8795 |
TNFRSF10B
CD262 DR5 KILLER KILLER/DR5 TRAIL-R2 TRAILR2 TRICK2 TRICK2A TRICK2B TRICKB ZTNFR9 |
tumor necrosis factor receptor superfamily, member 10b | Cycloheximide promotes the reaction [celecoxib results in increased expression of TNFRSF10B protein] |
increases expression
/ increases reaction |
protein |
15572759
|
D003513 | 8795 |
TNFRSF10B
CD262 DR5 KILLER KILLER/DR5 TRAIL-R2 TRAILR2 TRICK2 TRICK2A TRICK2B TRICKB ZTNFR9 |
tumor necrosis factor receptor superfamily, member 10b | Cycloheximide results in increased expression of TNFRSF10B mRNA |
increases expression
|
mRNA |
15572759
|
D003513 | 8795 |
TNFRSF10B
CD262 DR5 KILLER KILLER/DR5 TRAIL-R2 TRAILR2 TRICK2 TRICK2A TRICK2B TRICKB ZTNFR9 |
tumor necrosis factor receptor superfamily, member 10b | [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [sodium arsenite results in increased expression of and results in increased localization of TNFRSF10B protein]] results in increased susceptibility to [TNFSF10 protein co-treated with Cycloheximide] |
affects cotreatment
/ increases expression / increases localization / increases reaction / increases response to substance |
protein |
18222423
|
D003513 | 4982 |
TNFRSF11B
OCIF OPG TR1 |
tumor necrosis factor receptor superfamily, member 11b | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of TNFRSF11B mRNA |
affects cotreatment
/ decreases expression |
mRNA |
19684285
|
D003513 | 943 |
TNFRSF8
CD30 D1S166E Ki-1 |
tumor necrosis factor receptor superfamily, member 8 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNFRSF8 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein] |
affects cotreatment
/ decreases reaction / increases activity / increases cleavage |
protein |
18222423
|
D003513 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein] |
affects cotreatment
/ decreases reaction / increases activity / increases cleavage |
protein |
18222423
|
D003513 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein |
affects cotreatment
/ increases activity / increases cleavage |
protein |
18222423
|
D003513 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP9 protein |
affects cotreatment
/ increases activity / increases cleavage |
protein |
18222423
|
D003513 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein |
affects cotreatment
/ increases cleavage |
protein |
18222423
|
D003513 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TNFSF10 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [sodium arsenite results in increased expression of and results in increased localization of TNFRSF10B protein]] results in increased susceptibility to [TNFSF10 protein co-treated with Cycloheximide] |
affects cotreatment
/ increases expression / increases localization / increases reaction / increases response to substance |
protein |
18222423
|
D003513 | 8600 |
TNFSF11
CD254 ODF OPGL OPTB2 RANKL TRANCE hRANKL2 sOdf |
tumor necrosis factor (ligand) superfamily, member 11 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TNFSF11 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 7134 |
TNNC1
CMD1Z CMH13 TN-C TNC TNNC |
troponin C type 1 (slow) | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNNC1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
11007951
|
D003513 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | Cycloheximide inhibits the reaction [Fluorouracil results in increased expression of TP53 protein] |
decreases reaction
/ increases expression |
protein |
15016801
|
D003513 | 7157 |
TP53
BCC7 LFS1 P53 TRP53 |
tumor protein p53 | TP53 mutant form results in increased susceptibility to Cycloheximide |
increases response to substance
|
mutant form |
21875941
|
D003513 | 9537 |
TP53I11
PIG11 |
tumor protein p53 inducible protein 11 | Cycloheximide inhibits the reaction [arsenic trioxide results in increased expression of TP53I11 mRNA] |
decreases reaction
/ increases expression |
mRNA |
19333544
|
D003513 | 9537 |
TP53I11
PIG11 |
tumor protein p53 inducible protein 11 | Cycloheximide results in decreased expression of TP53I11 mRNA |
decreases expression
|
mRNA |
19333544
|
D003513 | 8626 |
TP63
AIS B(p51A) B(p51B) EEC3 KET LMS NBP OFC8 RHS SHFM4 TP53CP TP53L TP73L p40 p51 p53CP p63 p73H p73L |
tumor protein p63 | Cycloheximide inhibits the reaction [trichostatin A results in increased expression of TP63 protein alternative form] |
decreases reaction
/ increases expression |
protein |
20043870
|
D003513 | 10426 |
TUBGCP3
104p GCP3 Grip104 SPBC98 Spc98 Spc98p |
tubulin, gamma complex associated protein 3 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TUBGCP3 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 7296 |
TXNRD1
GRIM-12 TR TR1 TRXR1 TXNR |
thioredoxin reductase 1 (EC:1.8.1.9) | Cycloheximide inhibits the reaction [Acrolein results in increased expression of TXNRD1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15652504
|
D003513 | 7296 |
TXNRD1
GRIM-12 TR TR1 TRXR1 TXNR |
thioredoxin reductase 1 (EC:1.8.1.9) | Cycloheximide inhibits the reaction [sulforafan results in increased expression of TXNRD1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
12663510
|
D003513 | 7298 |
TYMS
HST422 TMS TS |
thymidylate synthetase (EC:2.1.1.45) | Cycloheximide inhibits the reaction [trichostatin A results in decreased expression of TYMS mRNA] |
decreases expression
/ decreases reaction |
mRNA |
17172411
|
D003513 | 7299 |
TYR
ATN CMM8 OCA1 OCA1A OCAIA SHEP3 |
tyrosinase (EC:1.14.18.1) | Cycloheximide inhibits the reaction [Quercetin results in increased activity of TYR protein] |
decreases reaction
/ increases activity |
protein |
14717847
|
D003513 | 54658 |
UGT1A1
BILIQTL1 GNT1 HUG-BR1 UDPGT UDPGT_1-1 UGT1 UGT1A |
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) | [Cycloheximide co-treated with Estradiol] results in decreased expression of UGT1A1 mRNA |
affects cotreatment
/ decreases expression |
mRNA |
15072547
|
D003513 | 54658 |
UGT1A1
BILIQTL1 GNT1 HUG-BR1 UDPGT UDPGT_1-1 UGT1 UGT1A |
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) | Cycloheximide results in decreased expression of UGT1A1 mRNA |
decreases expression
|
mRNA |
15072547
|
D003513 | 7366 |
UGT2B15
HLUG4 UDPGT_2B8 UDPGT2B15 UDPGTH3 UGT2B8 |
UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) | Cycloheximide results in increased expression of UGT2B15 mRNA |
increases expression
|
mRNA |
16690804
|
D003513 | 7422 |
VEGFA
MVCD1 VEGF VPF |
vascular endothelial growth factor A | Cycloheximide inhibits the reaction [sodium arsenite results in increased expression of VEGFA mRNA] |
decreases reaction
/ increases expression |
mRNA |
11641398
|
D003513 | 7422 |
VEGFA
MVCD1 VEGF VPF |
vascular endothelial growth factor A | Cycloheximide results in increased expression of VEGFA mRNA |
increases expression
|
mRNA |
11641398
|
D003513 | 7436 |
VLDLR
CARMQ1 CHRMQ1 VLDLRCH |
very low density lipoprotein receptor | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of VLDLR mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 7447 |
VSNL1
HLP3 HPCAL3 HUVISL1 VILIP VILIP-1 |
visinin-like 1 | Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of VSNL1 mRNA] |
decreases expression
/ decreases reaction |
mRNA |
11007951
|
D003513 | 10413 |
YAP1
YAP YAP2 YAP65 YKI |
Yes-associated protein 1 | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of YAP1 mRNA |
affects cotreatment
/ increases expression |
mRNA |
19684285
|
OMIM | preferred title | UniProt |
---|---|---|
#100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
#202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
#103780 | Alcohol dependence |
P08172
P14416 P31645 |
#612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
#614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
#300068 | Androgen insensitivity syndrome; ais |
P10275
|
#312300 | Androgen insensitivity, partial; pais |
P10275
|
#614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
#602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
%606641 | Body mass index; bmi |
P37231
|
#300615 | Brunner syndrome |
P21397
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#609338 | Carotid intimal medial thickness 1 |
P37231
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#114500 | Colorectal cancer; crc |
P84022
|
#162800 | Cyclic neutropenia |
P08246
|
#127750 | Dementia, lewy body; dlb |
P37840
|
#612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#614557 | Ehlers-danlos syndrome with progressive kyphoscoliosis, myopathy, and hearing loss; edskmh |
Q9NWM8
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#133239 | Esophageal cancer |
P04637
|
#615363 | Estrogen resistance; estrr |
P03372
|
#613659 | Gastric cancer |
P04626
|
#137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
#231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
#137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 P37231 |
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
#143100 | Huntington disease; hd |
P42858
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#603932 | Intervertebral disc disease; idd |
P14780
|
#151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#613688 | Long qt syndrome 2; lqt2 |
Q12809
|
#211980 | Lung cancer |
P00533
P04626 P04637 |
#612371 | Major affective disorder 7; mafd7 |
P17861
|
#608516 | Major depressive disorder; mdd |
P08172
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
%300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
#613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
#126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
#159900 | Myoclonic dystonia |
P14416
|
#202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
#257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
#601665 | Obesity |
P32245
P37231 |
#164230 | Obsessive-compulsive disorder; ocd |
P31645
|
#604715 | Orthostatic intolerance |
P23975
|
#259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
#167000 | Ovarian cancer |
P04626
|
#260500 | Papilloma of choroid plexus; cpp |
P04637
|
#168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
#605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
#168600 | Parkinson disease, late-onset; pd |
P37840
|
#613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
#607276 | Resting heart rate, variation in |
P08588
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
#609620 | Short qt syndrome 1; sqt1 |
Q12809
|
#313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
#253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
#253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
#253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
#271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
#275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
#190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
#277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
#610379 | West nile virus, susceptibility to |
P51681
|
#112100 | Yt blood group antigen |
P22303
|
KEGG | disease name | UniProt |
---|---|---|
H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) |
H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) |
H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) |
H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
H00436 | Osteopetrosis |
P00918
(related)
|
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) |
H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) |
H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
H00006 | Hairy-cell leukemia |
P04637
(related)
|
H00008 | Burkitt lymphoma |
P04637
(related)
|
H00009 | Adult T-cell leukemia |
P04637
(related)
|
H00010 | Multiple myeloma |
P04637
(related)
|
H00013 | Small cell lung cancer |
P04637
(related)
|
H00014 | Non-small cell lung cancer |
P04637
(related)
|
H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P14780 (related) P35354 (related) |
H00029 | Vulvar cancer |
P04637
(related)
|
H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
H00033 | Adrenal carcinoma |
P04637
(related)
|
H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
H00038 | Malignant melanoma |
P04637
(related)
|
H00039 | Basal cell carcinoma |
P04637
(related)
|
H00040 | Squamous cell carcinoma |
P04637
(related)
|
H00041 | Kaposi's sarcoma |
P04637
(related)
|
H00044 | Cancer of the anal canal |
P04637
(related)
|
H00047 | Gallbladder cancer |
P04637
(related)
|
H00048 | Hepatocellular carcinoma |
P04637
(related)
|
H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
H01007 | Choroid plexus papilloma |
P04637
(related)
|
H00021 | Renal cell carcinoma |
P04637
(marker)
|
H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
H00079 | Asthma |
P07550
(related)
|
H00100 | Neutropenic disorders |
P08246
(related)
|
H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
H00024 | Prostate cancer |
P10275
(related)
|
H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H00342 | Tuberculosis |
P11473
(related)
|
H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00479 | Metaphyseal dysplasias |
P14780
(related)
|
H00548 | Brunner syndrome |
P21397
(related)
|
H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00409 | Type II diabetes mellitus |
P37231
(related)
|
H00057 | Parkinson's disease (PD) |
P37840
(related)
|
H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
H00059 | Huntington's disease (HD) |
P42858
(related)
|
H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
|
H00720 | Long QT syndrome |
Q12809
(related)
|
H00725 | Short QT syndrome |
Q12809
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
Q16637 (related) |
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
MeSH disease | OMIM | compound | disease name | evidence type |
reference
pmid |
---|---|---|---|---|---|
D000647 | D003513 | Amnesia |
marker/mechanism
|
2273650
2547386 7617693 12650838 |
|
D019970 | D003513 | Cocaine-Related Disorders |
therapeutic
|
16777145
|
|
D056486 | D003513 | Drug-Induced Liver Injury |
marker/mechanism
|
19395591
22331495 |
|
D005909 | D003513 | Glioblastoma |
marker/mechanism
|
7841041
7861226 |
|
D006949 | D003513 | Hyperlipidemias |
therapeutic
|
69995
|
|
D007174 | D003513 | Impulse Control Disorders |
therapeutic
|
6458665
|
|
D007249 | D003513 | Inflammation |
marker/mechanism
|
21146893
|
|
D007859 | D003513 | Learning Disorders |
marker/mechanism
|
9147253
16343452 |
|
D008223 | D003513 | Lymphoma |
therapeutic
|
19412536
|
|
D008569 | D003513 | Memory Disorders |
marker/mechanism
|
561405
6817363 |
|
D009135 | D003513 | Muscular Diseases |
therapeutic
|
6654876
|
|
D009336 | D003513 | Necrosis |
marker/mechanism
therapeutic |
171611
17617453 19041363 |
|
D009410 | D003513 | Nerve Degeneration |
therapeutic
|
9710261
23335626 |
|
D009422 | D003513 | Nervous System Diseases |
therapeutic
|
11756511
|
|
D011041 | D003513 | Poisoning |
therapeutic
|
22155090
|
|
D013226 | D003513 | Status Epilepticus |
therapeutic
|
7925839
|