PCIDB

KNApSAcK Metabolite C00005135

Index

Metabolite

Species

Human Protein
/ Gene in interactions

Related Diseases

Metabolite

KNApSAcK Entry

id	C00005135
Name	Asiaticalin
CAS RN	69292-77-9
Standard InChI	InChI=1S/C21H20O11/c22-7-13-15(26)17(28)18(29)21(31-13)32-20-16(27)14-11(25)5-10(24)6-12(14)30-19(20)8-1-3-9(23)4-2-8/h1-6,13,15,17-18,21-26,28-29H,7H2/t13-,15-,17?,18?,21+/m1/s1
Standard InChI (Main Layer)	InChI=1S/C21H20O11/c22-7-13-15(26)17(28)18(29)21(31-13)32-20-16(27)14-11(25)5-10(24)6-12(14)30-19(20)8-1-3-9(23)4-2-8/h1-6,13,15,17-18,21-26,28-29H,7H2

Cluster

Phytochemical cluster	No. 15
KCF-S cluster	No. 2

Link

ChEMBL

By standard InChI
By standard InChI Main Layer	CHEMBL233930 CHEMBL453290 CHEMBL1572115

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name	count
Euphyllophyta	3
eudicotyledons	1

Family

family name	count
Thelypteridaceae	2
Osmundaceae	1
Ranunculaceae	1

List (4)

* NCBI

KNApSAcK organism	*ID	*family	*plant class	*kingdom
Glaucidium palmatum	39106	Ranunculaceae	eudicotyledons	Viridiplantae
Osmunda asiatica	3283	Osmundaceae	Euphyllophyta	Viridiplantae
Thelypteris formosa	29617	Thelypteridaceae	Euphyllophyta	Viridiplantae
Thelypteris nipponica	746521	Thelypteridaceae	Euphyllophyta	Viridiplantae

Human Protein / Gene in interaction

10 ChEMBL Protein in interactions

accession	description	class description	compound	assay ID (# of activities)	# of diseases (OMIM / KEGG)
Q99700	Ataxin-2	Unclassified protein	CHEMBL1572115	CHEMBL2114784 (1)	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	CHEMBL1572115	CHEMBL1794585 (1)	0 / 0
P07237	Protein disulfide-isomerase	Enzyme	CHEMBL233930 CHEMBL1572115	CHEMBL1964080 (2) CHEMBL2114805 (2)	0 / 0
P15121	Aldose reductase	Enzyme	CHEMBL233930	CHEMBL1942674 (1)	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	CHEMBL1572115	CHEMBL1794569 (1)	1 / 1
P14679	Tyrosinase	Oxidoreductase	CHEMBL233930	CHEMBL814345 (1)	4 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	CHEMBL233930	CHEMBL1738588 (1)	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	CHEMBL233930	CHEMBL1794483 (1)	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	CHEMBL233930	CHEMBL1614211 (1)	0 / 0
P01215	Glycoprotein hormones alpha chain	Unclassified protein	CHEMBL233930	CHEMBL2114913 (1)	0 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM	preferred title	UniProt
#103470	Albinism, ocular, with sensorineural deafness	P14679
#203100	Albinism, oculocutaneous, type ia; oca1a	P14679
#606952	Albinism, oculocutaneous, type ib; oca1b	P14679
#601800	Skin/hair/eye pigmentation, variation in, 3; shep3	P14679
#183090	Spinocerebellar ataxia 2; sca2	Q99700
#278750	Xeroderma pigmentosum, variant type; xpv	Q9Y253

KEGG DISEASE (7)

KEGG	disease name	UniProt
H00081	Hashimoto's thyroiditis	P01215 (marker)
H00082	Graves' disease	P01215 (marker)
H00250	Congenital nongoitrous hypothyroidism (CHNG)	P01215 (marker)
H00168	Oculocutaneous albinism (OCA)	P14679 (related)
H00038	Malignant melanoma	P14679 (marker)
H00063	Spinocerebellar ataxia (SCA)	Q99700 (related)
H00403	Disorders of nucleotide excision repair	Q9Y253 (related)