PCIDB

KNApSAcK Metabolite C00005371

Metabolite

KNApSAcK Entry

id C00005371
Name Quercetin 3-alloside
CAS RN 90327-16-5
Standard InChI InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15-,17?,18?,21+/m1/s1
Standard InChI (Main Layer) InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 2

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL33027 CHEMBL309323 CHEMBL250450 CHEMBL251254 CHEMBL457304 CHEMBL1098724 CHEMBL2337335 CHEMBL2337336

KEGG

By LinkDB

CTD

By CAS RN

Human Protein / Gene in interaction

38 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q9NPH5 NADPH oxidase 4 Enzyme CHEMBL1098724 CHEMBL1249157 (1) CHEMBL1249158 (1)
CHEMBL1249160 (1)
0 / 0
Q16637 Survival motor neuron protein Unclassified protein CHEMBL33027 CHEMBL1613842 (1)
4 / 2
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL251254 CHEMBL1738312 (1)
0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL250450 CHEMBL1008559 (1) CHEMBL1693776 (1)
0 / 3
P06746 DNA polymerase beta Enzyme CHEMBL250450 CHEMBL251254 CHEMBL1614079 (2)
0 / 0
P04062 Glucosylceramidase Enzyme CHEMBL251254 CHEMBL1613818 (1)
6 / 4
P10253 Lysosomal alpha-glucosidase Hydrolase CHEMBL33027 CHEMBL250450 CHEMBL251254 CHEMBL1614175 (1) CHEMBL1614076 (3)
1 / 1
P02545 Prelamin-A/C Unclassified protein CHEMBL251254 CHEMBL1614544 (1)
11 / 10
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase CHEMBL250450 CHEMBL1014040 (2)
1 / 1
P18825 Alpha-2C adrenergic receptor Adrenergic receptor CHEMBL1098724 CHEMBL1120976 (1)
0 / 0
P07237 Protein disulfide-isomerase Enzyme CHEMBL33027 CHEMBL1964080 (1) CHEMBL2114805 (1)
0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein CHEMBL33027 CHEMBL250450 CHEMBL251254 CHEMBL1614166 (3)
1 / 0
P41145 Kappa-type opioid receptor Opioid receptor CHEMBL250450 CHEMBL926465 (1)
0 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr CHEMBL250450 CHEMBL2337335 CHEMBL2337336 CHEMBL2342404 (3)
1 / 1
P39748 Flap endonuclease 1 Enzyme CHEMBL33027 CHEMBL1794486 (1)
0 / 0
O75496 Geminin Unclassified protein CHEMBL33027 CHEMBL2114780 (1)
0 / 0
P41143 Delta-type opioid receptor Opioid receptor CHEMBL250450 CHEMBL926467 (1)
0 / 0
P15121 Aldose reductase Enzyme CHEMBL250450 CHEMBL1942674 (2)
0 / 0
Q9Y253 DNA polymerase eta Enzyme CHEMBL33027 CHEMBL1794569 (1)
1 / 1
P09923 Intestinal-type alkaline phosphatase Enzyme CHEMBL250450 CHEMBL1738679 (1) CHEMBL1738192 (1)
0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme CHEMBL250450 CHEMBL1738602 (1)
3 / 1
P14679 Tyrosinase Oxidoreductase CHEMBL250450 CHEMBL814345 (1)
4 / 2
P06280 Alpha-galactosidase A Enzyme CHEMBL251254 CHEMBL1614217 (1)
1 / 1
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL251254 CHEMBL1614521 (1)
0 / 0
P10696 Alkaline phosphatase, placental-like Enzyme CHEMBL250450 CHEMBL1738040 (1)
0 / 1
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette CHEMBL250450 CHEMBL1687393 (1) CHEMBL1687394 (1)
2 / 0
P35372 Mu-type opioid receptor Opioid receptor CHEMBL250450 CHEMBL926466 (1)
0 / 0
Q9UNA4 DNA polymerase iota Enzyme CHEMBL33027 CHEMBL1794483 (1)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL33027 CHEMBL250450 CHEMBL251254 CHEMBL1614211 (3)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL250450 CHEMBL251254 CHEMBL1614421 (2)
4 / 3
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor CHEMBL250450 CHEMBL993916 (1)
1 / 0
P34949 Mannose-6-phosphate isomerase Enzyme CHEMBL33027 CHEMBL1614255 (1)
1 / 1
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL33027 CHEMBL1794536 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL33027 CHEMBL250450 CHEMBL251254 CHEMBL1613914 (3)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL250450 CHEMBL251254 CHEMBL1738442 (2)
0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein CHEMBL33027 CHEMBL1613933 (1)
0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein CHEMBL33027 CHEMBL1613933 (1)
1 / 6
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL33027 CHEMBL2114738 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (43)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#614490 Blood group, junior system; jr Q9UNQ0
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#602579 Congenital disorder of glycosylation, type ib; cdg1b P34949
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#232300 Glycogen storage disease ii P10253
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#601626 Leukemia, acute myeloid; aml P36888
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#614674 Periodic fever, menstrual cycle-dependent P08908
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#275210 Restrictive dermopathy, lethal P02545
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (34)

KEGG disease name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00213 Hypophosphatasia P05186 (related)
H00125 Fabry disease P06280 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00023 Testicular cancer P10696 (marker)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00118 Congenital disorders of glycosylation (CDG) type I P34949 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00192 Xanthinuria P47989 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)