KNApSAcK Metabolite C00000559
Metabolite
KNApSAcK Entry
| id | C00000559 |
|---|---|
| Name | Fonsecin |
| CAS RN | 3748-39-8 |
| Standard InChI | InChI=1S/C15H14O6/c1-15(19)6-9(17)13-11(21-15)4-7-3-8(16)5-10(20-2)12(7)14(13)18/h3-5,16,18-19H,6H2,1-2H3 |
| Standard InChI (Main Layer) | InChI=1S/C15H14O6/c1-15(19)6-9(17)13-11(21-15)4-7-3-8(16)5-10(20-2)12(7)14(13)18/h3-5,16,18-19H,6H2,1-2H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 3957 |
Link
ChEMBL
| By standard InChI | CHEMBL1391235 |
|---|---|
| By standard InChI Main Layer | CHEMBL1391235 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Aspergillaceae | 2 |
List (2)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Aspergillus fonsecaeus | 5052 | Aspergillaceae | Fungi | |
| Aspergillus tubingensis | 5068 | Aspergillaceae | Fungi |
Human Protein / Gene in interaction
21 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | CHEMBL1391235 |
CHEMBL1738312
(1)
|
0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | CHEMBL1391235 |
CHEMBL2114784
(1)
|
1 / 1 |
| P06746 | DNA polymerase beta | Enzyme | CHEMBL1391235 |
CHEMBL1614079
(1)
|
0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | CHEMBL1391235 |
CHEMBL1794585
(1)
|
0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | CHEMBL1391235 |
CHEMBL1614166
(1)
|
1 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | CHEMBL1391235 |
CHEMBL1794486
(1)
|
0 / 0 |
| P42858 | Huntingtin | Unclassified protein | CHEMBL1391235 |
CHEMBL1613918
(1)
|
1 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | CHEMBL1391235 |
CHEMBL1794584
(1)
|
2 / 0 |
| O75496 | Geminin | Unclassified protein | CHEMBL1391235 |
CHEMBL2114780
(1)
|
0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | CHEMBL1391235 |
CHEMBL1794569
(1)
|
1 / 1 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | CHEMBL1391235 |
CHEMBL1614410
(1)
CHEMBL1614531
(1)
|
1 / 3 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | CHEMBL1391235 |
CHEMBL1614342
(1)
|
1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | CHEMBL1391235 |
CHEMBL1738588
(1)
|
0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | CHEMBL1391235 |
CHEMBL1794483
(1)
|
0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | CHEMBL1391235 |
CHEMBL1737991
(1)
|
0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | CHEMBL1391235 |
CHEMBL1614466
(1)
CHEMBL1614211
(1)
|
0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | CHEMBL1391235 |
CHEMBL1614421
(1)
CHEMBL1614502
(1)
|
4 / 3 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | CHEMBL1391235 |
CHEMBL1794536
(1)
|
0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | CHEMBL1391235 |
CHEMBL1613914
(1)
|
0 / 0 |
| O00255 | Menin | Unclassified protein | CHEMBL1391235 |
CHEMBL1614531
(1)
|
2 / 5 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | CHEMBL1391235 |
CHEMBL2354287
(1)
|
1 / 1 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (15)
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #143100 | Huntington disease; hd |
P42858
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (14)
| KEGG | disease name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|