KNApSAcK Metabolite C00007299
Metabolite
KNApSAcK Entry
| id | C00007299 |
|---|---|
| Name | Phosphorylcholine |
| CAS RN | 107-73-3 |
| Standard InChI | InChI=1S/C5H14NO4P/c1-6(2,3)4-5-10-11(7,8)9/h4-5H2,1-3H3,(H-,7,8,9)/p+1 |
| Standard InChI (Main Layer) | InChI=1S/C5H14NO4P/c1-6(2,3)4-5-10-11(7,8)9/h4-5H2,1-3H3,(H-,7,8,9) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 8719 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer | CHEMBL323804 |
KEGG
| By LinkDB | C00588 |
|---|
CTD
| By CAS RN | D010767 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 1 |
Family
| family name | count |
|---|---|
| Brassicaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Arabidopsis thaliana | 3702 | Brassicaceae | rosids | Viridiplantae |
Human Protein / Gene in interaction
CTD interaction (9)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| D010767 | 2194 |
FASN
FAS OA-519 SDR27X1 |
fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39) | [Cerulenin results in decreased activity of FASN protein] which results in decreased abundance of Phosphorylcholine |
decreases abundance
/ decreases activity |
protein |
18723500
|
| D010767 | 2194 |
FASN
FAS OA-519 SDR27X1 |
fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39) | [orlistat results in decreased activity of FASN protein] which results in decreased abundance of Phosphorylcholine |
decreases abundance
/ decreases activity |
protein |
18723500
|
| D010767 | 4312 |
MMP1
CLG CLGN |
matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) | Genistein inhibits the reaction [Phosphorylcholine analog results in increased expression of MMP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15878362
|
| D010767 | 4312 |
MMP1
CLG CLGN |
matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) | herbimycin inhibits the reaction [Phosphorylcholine analog results in increased expression of MMP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15878362
|
| D010767 | 4312 |
MMP1
CLG CLGN |
matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) | Phosphorylcholine analog results in increased expression of MMP1 mRNA |
increases expression
|
mRNA |
15878362
|
| D010767 | 7076 |
TIMP1
CLGI EPA EPO HCI TIMP |
TIMP metallopeptidase inhibitor 1 | Genistein inhibits the reaction [Phosphorylcholine analog results in increased expression of TIMP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15878362
|
| D010767 | 7076 |
TIMP1
CLGI EPA EPO HCI TIMP |
TIMP metallopeptidase inhibitor 1 | herbimycin inhibits the reaction [Phosphorylcholine analog results in increased expression of TIMP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
15878362
|
| D010767 | 7076 |
TIMP1
CLGI EPA EPO HCI TIMP |
TIMP metallopeptidase inhibitor 1 | Phosphorylcholine analog results in increased expression of TIMP1 mRNA |
increases expression
|
mRNA |
15878362
|
| D010767 | 7124 |
TNF
DIF TNF-alpha TNFA TNFSF2 |
tumor necrosis factor | Phosphorylcholine analog results in increased expression of TNF mRNA |
increases expression
|
mRNA |
15878362
|