KNApSAcK Metabolite C00007407
Metabolite
KNApSAcK Entry
| id | C00007407 |
|---|---|
| Name | Glycerol 2-phosphate |
| CAS RN | 17181-54-3 |
| Standard InChI | InChI=1S/C3H9O6P/c4-1-3(2-5)9-10(6,7)8/h3-5H,1-2H2,(H2,6,7,8) |
| Standard InChI (Main Layer) | InChI=1S/C3H9O6P/c4-1-3(2-5)9-10(6,7)8/h3-5H,1-2H2,(H2,6,7,8) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 5111 |
Link
ChEMBL
| By standard InChI | CHEMBL1232903 |
|---|---|
| By standard InChI Main Layer | CHEMBL1232903 |
KEGG
| By LinkDB | C02979 |
|---|
CTD
| By CAS RN | C031463 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 1 |
Family
| family name | count |
|---|---|
| Brassicaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Arabidopsis thaliana | 3702 | Brassicaceae | rosids | Viridiplantae |
Human Protein / Gene in interaction
2 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q13951 | Core-binding factor subunit beta | Unclassified protein | CHEMBL1232903 |
CHEMBL1613933
(1)
|
0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | CHEMBL1232903 |
CHEMBL1613933
(1)
|
1 / 6 |
CTD interaction (19)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C031463 | 249 |
ALPL
AP-TNAP APTNAP HOPS TNAP TNSALP |
alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) | ALPL protein results in increased hydrolysis of beta-glycerophosphoric acid |
increases hydrolysis
|
protein |
18500657
|
| C031463 | 249 |
ALPL
AP-TNAP APTNAP HOPS TNAP TNSALP |
alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) | [ALPL protein results in increased hydrolysis of beta-glycerophosphoric acid] which results in increased abundance of Phosphates |
increases abundance
/ increases hydrolysis |
protein |
18500657
|
| C031463 | 249 |
ALPL
AP-TNAP APTNAP HOPS TNAP TNSALP |
alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) | beta-glycerophosphoric acid results in increased activity of ALPL protein |
increases activity
|
protein |
18500657
|
| C031463 | 249 |
ALPL
AP-TNAP APTNAP HOPS TNAP TNSALP |
alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) | beta-glycerophosphoric acid results in increased expression of ALPL mRNA |
increases expression
|
mRNA |
18500657
|
| C031463 | 249 |
ALPL
AP-TNAP APTNAP HOPS TNAP TNSALP |
alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) | Levamisole inhibits the reaction [beta-glycerophosphoric acid results in increased activity of ALPL protein] |
decreases reaction
/ increases activity |
protein |
18500657
|
| C031463 | 249 |
ALPL
AP-TNAP APTNAP HOPS TNAP TNSALP |
alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) | Levamisole inhibits the reaction [beta-glycerophosphoric acid results in increased expression of ALPL mRNA] |
decreases reaction
/ increases expression |
mRNA |
18500657
|
| C031463 | 632 |
BGLAP
BGP OC OCN |
bone gamma-carboxyglutamate (gla) protein | [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of BGLAP protein |
affects cotreatment
/ increases expression |
protein |
17692823
|
| C031463 | 5167 |
ENPP1
ARHR2 M6S1 NPP1 NPPS PC-1 PCA1 PDNP1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 (EC:3.1.4.1 3.6.1.9) | beta-glycerophosphoric acid results in increased activity of ENPP1 protein |
increases activity
|
protein |
18500657
|
| C031463 | 5167 |
ENPP1
ARHR2 M6S1 NPP1 NPPS PC-1 PCA1 PDNP1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 (EC:3.1.4.1 3.6.1.9) | beta-glycerophosphoric acid results in increased expression of ENPP1 mRNA |
increases expression
|
mRNA |
18500657
|
| C031463 | 5167 |
ENPP1
ARHR2 M6S1 NPP1 NPPS PC-1 PCA1 PDNP1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 (EC:3.1.4.1 3.6.1.9) | Levamisole inhibits the reaction [beta-glycerophosphoric acid results in increased activity of ENPP1 protein] |
decreases reaction
/ increases activity |
protein |
18500657
|
| C031463 | 5167 |
ENPP1
ARHR2 M6S1 NPP1 NPPS PC-1 PCA1 PDNP1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 (EC:3.1.4.1 3.6.1.9) | Levamisole inhibits the reaction [beta-glycerophosphoric acid results in increased expression of ENPP1 mRNA] |
decreases reaction
/ increases expression |
mRNA |
18500657
|
| C031463 | 8074 |
FGF23
ADHR FGFN HPDR2 HYPF PHPTC |
fibroblast growth factor 23 | beta-glycerophosphoric acid results in increased expression of FGF23 mRNA |
increases expression
|
mRNA |
15542045
|
| C031463 | 5251 |
PHEX
HPDR HPDR1 HYP HYP1 LXHR PEX XLH |
phosphate regulating endopeptidase homolog, X-linked | beta-glycerophosphoric acid results in increased expression of PHEX mRNA |
increases expression
|
mRNA |
18500657
|
| C031463 | 5251 |
PHEX
HPDR HPDR1 HYP HYP1 LXHR PEX XLH |
phosphate regulating endopeptidase homolog, X-linked | Foscarnet inhibits the reaction [beta-glycerophosphoric acid results in increased expression of PHEX mRNA] |
decreases reaction
/ increases expression |
mRNA |
18500657
|
| C031463 | 5251 |
PHEX
HPDR HPDR1 HYP HYP1 LXHR PEX XLH |
phosphate regulating endopeptidase homolog, X-linked | Levamisole inhibits the reaction [beta-glycerophosphoric acid results in increased expression of PHEX mRNA] |
decreases reaction
/ increases expression |
mRNA |
18500657
|
| C031463 | 860 |
RUNX2
AML3 CBF-alpha-1 CBFA1 CCD CCD1 CLCD OSF-2 OSF2 PEA2aA PEBP2aA |
runt-related transcription factor 2 | [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 mRNA |
affects cotreatment
/ increases expression |
mRNA |
17692823
|
| C031463 | 6678 |
SPARC
ON |
secreted protein, acidic, cysteine-rich (osteonectin) | [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SPARC protein |
affects cotreatment
/ increases expression |
protein |
17692823
|
| C031463 | 6696 |
SPP1
BNSP BSPI ETA-1 OPN |
secreted phosphoprotein 1 | [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SPP1 protein |
affects cotreatment
/ increases expression |
protein |
17692823
|
| C031463 | 6901 |
TAZ
BTHS CMD3A EFE EFE2 G4.5 LVNCX Taz1 |
tafazzin | [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of TAZ mRNA |
affects cotreatment
/ increases expression |
mRNA |
17692823
|
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (1)
| OMIM | preferred title | UniProt |
|---|---|---|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
KEGG DISEASE (4)
| KEGG | disease name | UniProt |
|---|---|---|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|