KCF-S cluster No. 107 (46 metabolites)

Corresponding Phytochemical cluster No. 38

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (46)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	102
Magnoliophyta	8
Embryophyta	3

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Cumulative family count

class name	count
Asteraceae	102
Magnoliaceae	6
Frullaniaceae	3
Lauraceae	1
Aristolochiaceae	1

KEGG BRITE br08003

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Categories (2)

br08003 Category	# of metabolite
Germacrenes	7
Others	1

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metabolites link (8)

br08003 Category	KEGG ID	KNApSAcK ID
Germacrenes	C09304	C00003220
Others	C09345	C00003222
Germacrenes	C09355	C00003228
Germacrenes	C09382	C00003240
Germacrenes	C09440	C00003277
Germacrenes	C09540	C00003361
Germacrenes	C09542	C00003362
Germacrenes	C09556	C00003371

Metabolite list (46)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00003220	Artemisiifolin
C00003222	Artemorin
C00003228	Chamissonin
C00003240	Costunolide	CHEMBL86416 CHEMBL190377 CHEMBL1575037	C002602	10 / 7 / 15	0 / 3
C00003277	Eupatolide	CHEMBL503702 CHEMBL485296	C001200
C00003361	Ridentin / Ridentin A
C00003362	Salonitenolide	CHEMBL270061	C011103
C00003371	Tamaulipin A	CHEMBL505577
C00011769	3beta-Hydroxyanhydroverlotorin / 3beta-Hydroxy-1-oxo-4,10(14),11(13)-germacratrien-12,6alpha-olide
C00011770	Pulverulide
C00011775	2alpha-Hydroxyeupatolide
C00011801	Tavulin / Tatridin A	CHEMBL1087406
C00011802	Taridin B / Tatridin B	CHEMBL191412 CHEMBL430091		3 / 0 / 0
C00011813	Budlein B / Deacetylovatifolin
C00011822	Stenophyllolide
C00011825	Albicolid
C00012170	Melampolide	CHEMBL86416 CHEMBL190377 CHEMBL1575037		10 / 7 / 15
C00012176	Dehydroartemorin / Anhydroverlotorin
C00012179	Verlotorin / Peroxycostunolide
C00012181	[3aS-(3aR*,5E,7R*,10E,11aR*)]-3a,4,7,8,9,11a-Hexahydro-7-hydroxy-6,10-dimethyl-3-methylenecyclodeca[b]furan-2(3H)-one
C00012182	[3aS-(3aR*,6Z,8R*,10Z,11aS*)]-3a,4,5,8,9,11a-Hexahydro-8-hydroxy-6,10-dimethyl-3-methylenecyclodeca[b]furan-2(3H)-one	CHEMBL505577
C00012183	Tamaulipin B	CHEMBL251598
C00012184	Hanfillin / Chanfillin / Hanphyllin / Hanphilline / 3beta-Hydroxycostunolide	CHEMBL251598
C00012187	Heliangolide / (-)-Heliangolide	CHEMBL251598
C00012188	Hispanolide
C00012195	[3aR-(3aR*,4R*,6E,10E,11aS*)]-3a,4,5,8,9,11a-hexahydro-4-hydroxy-6,10-dimethyl-3-methylene-Cyclodeca[b]furan-2(3H)-one	CHEMBL503702 CHEMBL485296
C00012197	Haageanolide
C00012202	Soulangianolide A
C00012203	8-Deoxysalonitenolide
C00012331	Tanachin / 1-epi-Tatridin B / 1alpha-Hydroxy-1-desoxotamirin	CHEMBL191412 CHEMBL430091		3 / 0 / 0
C00012332	Tamirin	CHEMBL363460 CHEMBL1087405		3 / 0 / 0
C00012380	Inunolide
C00012383	[3aR-(3aR*,5E,8R*,9E,11aS*)]-3a,4,7,8,11,11a-Hexahydro-8-hydroxy-6,10-dimethyl-3-methylenecyclodeca[b]furan-2(3H)-one
C00012384	Maroniolide
C00012386	Chamissellin / Deacetyllaurenobiolide / Desacetyllaurenobiolide
C00012388	Liabinolide
C00012393	Frutescin
C00021699	9beta-Hydroxy costunolide
C00021705	Germacrene-D-lactone
C00022625	2alpha-Hydroxyartemorin
C00034333	Urospermal A
C00039131	epi-Isocostunolide / (-)-epi-Isocostunolide
C00041689	Neobritannilactone B	CHEMBL503702 CHEMBL485296
C00044742	Eleganolactone B
C00049977	allo-Schkuhriolide	CHEMBL472440
C00050219	Schkuhrioidiol / (+)-Schkuhrioidiol

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00003240 C00011802 C00012170 C00012331 C00012332	0 / 0
Q00653	Nuclear factor NF-kappa-B p100 subunit	Transcription Factor	C00003240 C00011802 C00012170 C00012331 C00012332	0 / 0
Q04206	Transcription factor p65	Transcription Factor	C00003240 C00011802 C00012170 C00012331 C00012332	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00003240 C00012170	1 / 1
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00003240 C00012170	0 / 0
P03372	Estrogen receptor	NR3A1	C00003240 C00012170	1 / 1
O00255	Menin	Unclassified protein	C00003240 C00012170	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00003240 C00012170	1 / 2
P11473	Vitamin D3 receptor	NR1I1	C00003240 C00012170	2 / 3
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00003240 C00012170	0 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions