KCF-S cluster No. 113 (45 metabolites)

Corresponding Phytochemical cluster No. 19

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (45)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	22
asterids	14
Magnoliophyta	12
Euphyllophyta	7
eudicotyledons	7
Spermatophyta	4
Liliopsida	4

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Cumulative family count (Top 20)

class name	count
Lauraceae	12
Rubiaceae	8
Polygonaceae	7
Ericaceae	4
Davalliaceae	4
Hippocastanaceae	4
Pinaceae	4
Rhizophoraceae	3
Vitaceae	3
Rosaceae	3
Gleicheniaceae	3
Fabaceae	2
Anacardiaceae	2
Dioscoreaceae	2
Arecaceae	2
Apocynaceae	2
Malpighiaceae	1
Malvaceae	1
Euphorbiaceae	1
Celastraceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Proanthocyanidins	1

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metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Proanthocyanidins	C10222	C00002918

Metabolite list (45)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002918	Epicatechin-(4beta->8)5-epicatechin
C00009066	[3,5,7,4'-Tetrahydroxyflavan-(4->8)]3-3,4,5,7,4'-pentahydroxyflavan
C00009101	Kandelin B3
C00009102	Davallin		C073481
C00009103	Epicatechin-(4beta->6)-epicatechin-(4beta->8)-epicatechin-(4beta->6)-epicatechin
C00009104	Catechin-(4alpha->6)-[epicatechin-(4beta->8)]2-epicatechin
C00009105	[Epicatechin-(4beta->8)]2-epicatechin-(4beta->6)-catechin
C00009106	Arecatannin A2
C00009107	Cinnamtannin A1
C00009108	[Epicatechin-(4beta->8)]4-catechin	CHEMBL592373		2 / 3 / 4
C00009109	[Epicatechin-(4beta->8)]4-epicatechin	CHEMBL592373		2 / 3 / 4
C00009122	[Epigallocatechin-(4->8)]3-epigallocatechin
C00009155	Fisetinidol-(4alpha->6)-fisetinidol-(4alpha->8)-catechin-(6->4alpha)-fisetinidol
C00009156	Fisetinidol-(4beta->6)-fisetinidol-(4beta->8)-catechin-(6->4alpha)-fisetinidol
C00009157	ent-Fisetinidol-(4alpha->6)-ent-fisetinidol-(4alpha->8)-catechin-(6->4alpha)-ent-fisetinidol
C00009158	ent-Fisetinidol-(4beta->6)-ent-fisetinidol-(4beta->8)-catechin-(6->4alpha)-ent-fisetinidol
C00009187	Kandelin B1 / Cinchonain-1a-(4beta->8)-epicatechin-(4beta->8)-epicatechin
C00009188	Kandelin B4 / Cinchonain-1b-(4beta->8)-epicatechin-(4beta->8)-catechin
C00009220	[3-O-Galloylepicatechin-(4beta->6)]2-epicatechin-3-O-gallate
C00009221	3-O-Galloylepicatechin-(4beta->6)-3-O-galloylepicatechin-(4beta->8)-catechin
C00009222	3-O-Galloylepicatechin-(4beta->6)-3-O-galloylepicatechin-(4beta->8)-epicatechin-3-O-gallate
C00009223	3-O-Galloylepicatechin-(4beta->8)-3-O-galloylepicatechin-(4beta->6)-catechin
C00009224	[Epicatechin-(4beta-8)]2-epicatechin-3-O-gallate
C00009225	Epicatechin-(4beta->8)-3-O-galloylepicatechin-(4beta->8)-catechin
C00009226	[3-Galloylepicatechin-(4beta->8)]2-catechin
C00009227	3-O-Galloylepicatechin-(4beta->8)-3-O-galloyl-ent-epicatechin-(4alpha->8)-ent-epicatechin
C00009228	Epicatechin-(4beta->8)-3-O-galloylepicatechin-(4beta->8)-epicatechin-3-O-gallate
C00009229	[3-O-Galloylepicatechin-(4beta->8)]2-epicatechin-3-O-gallate	CHEMBL262261 CHEMBL386276		11 / 2 / 2
C00009244	Epicatechin-(4beta->8)-catechin-(4alpha->8)-catechin-3-O-(1-hydroxy-6-oxo-2-cyclohexene-1-carboxylate)
C00009271	Pavetannin C4
C00009272	Pavetannin C5
C00009273	Epiafzelechin-(4beta->8)-epicatechin-(2beta->7,4beta->8)-epicatechin-(4beta->8)-epicatechin
C00009302	Epicatechin-(2beta->7,4beta->8)-epicatechin-(4beta->8)-epicatechin-(4beta->6)-catechin
C00009303	Epicatechin-(2beta->7,4beta->8)-[epicatechin-(4beta->8)]2-catechin
C00009304	Pavetannin C2
C00009305	Pavetannin C3
C00009306	Pavetannin C 1	CHEMBL1213877
C00009307	Cinnamtannin D2	CHEMBL410924 CHEMBL411351 CHEMBL502146		11 / 2 / 2
C00009308	Cinnamtannin B2	CHEMBL410924 CHEMBL411351 CHEMBL502146		11 / 2 / 2
C00009309	Aesculitannin G
C00009310	Pavetannin D 1
C00009311	[Epicatechin-(4beta->8)]2-epicatechin-(2beta->7,4beta->8)-epicatechin-(4beta->8)-epicatechin
C00013284	Aesculitannin E / (+)-Aesculitannin E
C00013285	Parameritannin A1 / (2R,3R,4S,8S,14R,15R)-2,8-bis(3,4-Dihydroxyphenyl)-6-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-4-yl]-4-[(2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-8-yl]-3,4-dihydro-8,14-methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol	CHEMBL1213878 CHEMBL1823107		1 / 0 / 3
C00033288	Parameritannin A2

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q15139	Serine/threonine-protein kinase D1	Pkd	C00009229 C00009307 C00009308	0 / 0
P41743	Protein kinase C iota type	Iota	C00009229 C00009307 C00009308	0 / 0
P24723	Protein kinase C eta type	Eta	C00009229 C00009307 C00009308	1 / 0
Q05513	Protein kinase C zeta type	Iota	C00009229 C00009307 C00009308	0 / 0
Q04759	Protein kinase C theta type	Delta	C00009229 C00009307 C00009308	0 / 1
Q02156	Protein kinase C epsilon type	Eta	C00009229 C00009307 C00009308	0 / 0
O94806	Serine/threonine-protein kinase D3	Pkd	C00009229 C00009307 C00009308	0 / 0
P05771	Protein kinase C beta type	Alpha	C00009229 C00009307 C00009308	0 / 0
Q05655	Protein kinase C delta type	Delta	C00009229 C00009307 C00009308	0 / 0
P05129	Protein kinase C gamma type	Alpha	C00009229 C00009307 C00009308	1 / 1
P17252	Protein kinase C alpha type	Alpha	C00009229 C00009307 C00009308	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00009108 C00009109	1 / 3
P14780	Matrix metalloproteinase-9	M10A	C00009108 C00009109	2 / 2
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00013285	0 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions