KCF-S cluster No. 1179 (8 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (8)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	9

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Cumulative family count

class name	count
Theaceae	9

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (8)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00009348	Theaflavin	CHEMBL346119 CHEMBL403814 CHEMBL1512440	C056068	21 / 20 / 31	10 / 3
C00009349	Theaflavin 3-O-gallate	CHEMBL253536		1 / 0 / 7
C00009350	Theaflavin 3'-O-gallate	CHEMBL423795
C00009351	Theaflavin 3,3'-di-O-gallate	CHEMBL434864 CHEMBL402609 CHEMBL1451483		26 / 35 / 43
C00009353	Epitheaflagallin 3-O-gallate	CHEMBL349707
C00009354	Oolongtheanin	CHEMBL159756
C00041068	Neotheaflavin 3-O-gallate	CHEMBL253536		1 / 0 / 7
C00041209	Theaflavate B

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10415	Apoptosis regulator Bcl-2	Other cytosolic protein	C00009348 C00009349 C00009351 C00041068	0 / 7
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00009348 C00009351	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00009348 C00009351	1 / 2
P10828	Thyroid hormone receptor beta	NR1A2	C00009348 C00009351	3 / 1
P54132	Bloom syndrome protein	Enzyme	C00009348 C00009351	1 / 2
P51570	Galactokinase	Enzyme	C00009348 C00009351	1 / 1
P11473	Vitamin D3 receptor	NR1I1	C00009348 C00009351	2 / 3
O00255	Menin	Unclassified protein	C00009348 C00009351	2 / 5
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00009348 C00009351	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00009348 C00009351	1 / 1
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00009348 C00009351	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00009348 C00009351	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00009348 C00009351	3 / 3
Q9UBT6	DNA polymerase kappa	Enzyme	C00009348 C00009351	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00009348 C00009351	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00009348 C00009351	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00009348 C00009351	0 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00009348 C00009351	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00009348 C00009351	4 / 3
P29466	Caspase-1	C14	C00009348 C00009351	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00009348 C00009351	2 / 2
P55210	Caspase-7	C14	C00009351	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00009351	0 / 0
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00009351	4 / 2
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00009351	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00009351	11 / 10

10 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
581	BAX, BCL2L4	BCL2-associated X protein	C00009348
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00009348
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00009348
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00009348
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00009348
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00009348
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00009348
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00009348
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00009348
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00009348

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions