KCF-S cluster No. 119 (43 metabolites)

Corresponding Phytochemical cluster No. 51

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (43)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	45
Liliopsida	2
asterids	1

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Cumulative family count

class name	count
Meliaceae	25
Cucurbitaceae	11
Euphorbiaceae	4
Orchidaceae	2
Saccharomycetaceae	1
Moraceae	1
Asteraceae	1
Celastraceae	1
Salicaceae	1
Betulaceae	1
Rutaceae	1

KEGG BRITE br08003

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Categories (2)

br08003 Category	# of metabolite
Others	1
Dammarenes	1

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metabolites link (2)

br08003 Category	KEGG ID	KNApSAcK ID
Others	C08789	C00003678
Dammarenes	C19918	C00023785

Metabolite list (43)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00003678	Bryodulcosigenin	CHEMBL465204
C00011163	Butyrospermol / (-)-Butyrospermol	CHEMBL1835433
C00023785	Parkeol
C00024109	Boeticol / Antiquol B / (+)-Antiquol B	CHEMBL497823
C00030596	Karavilagenin A / (+)-Karavilagenin A	CHEMBL469190
C00030597	Karavilagenin B / (+)-Karavilagenin B	CHEMBL466941
C00030598	Karavilagenin C / (+)-Karavilagenin C	CHEMBL596244		1 / 1 / 0
C00031038	Piscidinol A / (-)-Piscidinol A	CHEMBL1508930		12 / 23 / 20
C00034061	Momordicine I / (+)-Momordicine I
C00034506	Euferol	CHEMBL497823
C00036470	23,26-Dihydroxy-tirucalla-7,24-dien-3-one / (-)-23,26-Dihydroxy-tirucalla-7,24-dien-3-one
C00036477	24S,25-Dihydroxytirucall-7-en-3-one
C00036697	Agrostophyllinone
C00039058	Dymacrin A / (+)-Dymacrin A
C00039059	Dymacrin B / (-)-Dymacrin B
C00039060	Dymacrin C / (+)-Dymacrin C
C00039061	Dymacrin D
C00039062	Dymacrin E / (+)-Dymacrin E
C00039063	Dymacrin F / (-)-Dymacrin F
C00039064	Dymacrin G / (-)-Dymacrin G
C00040493	Tirucalla-7,24-dien-3beta-ol	CHEMBL1835433
C00040825	3-Oxo-tirucalla-7,24-dien-21-al
C00042922	Rosacea acid B	CHEMBL487001		2 / 0 / 0
C00044448	3-epi-Flindissol
C00045521	16-Hydroxybutyrospermol	CHEMBL464492
C00045872	Dubione A / (-)-Dubione A	CHEMBL465316
C00045873	Dubione B / (-)-Dubione B	CHEMBL465316
C00045876	Dyvariabilin A / (-)-Dyvariabilin A
C00045883	Dyvariabilin H
C00046068	Kulactone	CHEMBL464664
C00046069	Kulinone	CHEMBL464491
C00046127	Meliastatin 1	CHEMBL465433
C00046140	Methyl kulonate	CHEMBL517173
C00046464	Tirucalla-7,24-diene-3beta,23-diol
C00047602	Toonaciliatin L / (-)-Toonaciliatin L
C00047647	19-Norlanosta-5,24-dien-11-one	CHEMBL563863		1 / 1 / 2
C00047747	Balsaminapentaol A / (+)-Balsaminapentaol A	CHEMBL1078341
C00047748	Balsaminol A / (+)-Balsaminol A	CHEMBL1078436
C00047749	Balsaminol B / (+)-Balsaminol B	CHEMBL1078437
C00048210	Toosendanic acid A	CHEMBL2021462 CHEMBL2021468
C00048211	Toosendanic acid B	CHEMBL2021462 CHEMBL2021468
C00048459	Kuguacin J
C00048463	Kuguacin N / (-)-Kuguacin N

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q16637	Survival motor neuron protein	Unclassified protein	C00031038	4 / 1
Q99700	Ataxin-2	Unclassified protein	C00031038	1 / 1
P06746	DNA polymerase beta	Enzyme	C00031038	0 / 0
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00031038	1 / 4
P08183	Multidrug resistance protein 1	drug	C00030598	1 / 0
P42858	Huntingtin	Unclassified protein	C00031038	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00031038	2 / 0
O75496	Geminin	Unclassified protein	C00031038	0 / 0
P40763	Signal transducer and activator of transcription 3	Transcription Factor	C00047647	1 / 2
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00031038	7 / 3
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00042922	0 / 0
P55055	Oxysterols receptor LXR-beta	NR1H3	C00042922	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00031038	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00031038	0 / 0
O00255	Menin	Unclassified protein	C00031038	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00031038	1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions