KCF-S cluster No. 1331 (7 metabolites)

Corresponding Phytochemical cluster No. 13


Plant Species


Cumulative plant class count

class name count
rosids 17
asterids 1
Magnoliophyta 1

Cumulative family count

class name count
Fabaceae 14
Meliaceae 3
Asteraceae 1
Myristicaceae 1

KEGG BRITE br08003 External link 512


Categories (1)

br08003 Category # of metabolite
Dihydrochalcones 2

metabolites link (3)

br08003 Category KEGG ID KNApSAcK ID
Dihydrochalcones C09774 C00000981
Dihydrochalcones C09807 C00000988
Dihydrochalcones C09807 C00038410

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00000981 External link 512 O-Methylodoratol
C00000988 External link 512 Odoratol
C00009794 External link 512 Angolensin
CHEMBL1373918
5 / 7 / 11
C00009795 External link 512 2-O-Methylangolensin
C00009796 External link 512 4-O-Methylangolensin
C00029530 External link 512 4-Hydroxy-3-methoxyacetophenone
C00038410 External link 512 alpha,2'-Dihydroxy-4,4'-dimethoxydihydrochalcone
/ (-)-alpha,2'-Dihydroxy-4,4'-dimethoxydihydrochalcone

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00009794 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00009794 0 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00009794 4 / 3
O00255 Menin Unclassified protein C00009794 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00009794 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (11)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)