KCF-S cluster No. 1370 (6 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (6)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	11

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Cumulative family count

class name	count
Phyllanthaceae	10
Polygalaceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (6)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002360	Securinine	CHEMBL303062 CHEMBL1355372 CHEMBL1358404 CHEMBL1495075 CHEMBL1529147 CHEMBL1965517	C000785	19 / 26 / 19
C00026161	4-Methoxynorsecurinine
C00038167	15alpha-Methoxy-14,15-dihydrophyllochrysine	CHEMBL398307
C00038277	4-Epiphyllanthine
C00039994	Phyllantidine / (-)-Phyllantidine	CHEMBL398499
C00040270	Securitinine

Human Protein / Gene in interactions

19 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002360	1 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00002360	4 / 1
Q99700	Ataxin-2	Unclassified protein	C00002360	1 / 1
P02545	Prelamin-A/C	Unclassified protein	C00002360	11 / 10
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002360	0 / 1
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00002360	1 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00002360	0 / 0
P42858	Huntingtin	Unclassified protein	C00002360	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00002360	2 / 0
O75496	Geminin	Unclassified protein	C00002360	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00002360	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002360	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002360	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002360	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002360	0 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00002360	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002360	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002360	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002360	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions