| class name | count |
|---|---|
| Spermatophyta | 30 |
| asterids | 11 |
| rosids | 7 |
| Magnoliophyta | 3 |
| Embryophyta | 1 |
| class name | count |
|---|---|
| Cupressaceae | 20 |
| Asteraceae | 10 |
| Araucariaceae | 8 |
| Fabaceae | 4 |
| Euphorbiaceae | 3 |
| Chloranthaceae | 3 |
| Cladoniaceae | 2 |
| Plectosphaerellaceae | 2 |
| Hymenochaetaceae | 1 |
| Podocarpaceae | 1 |
| Pinaceae | 1 |
| Porellaceae | 1 |
| Lamiaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00022225
|
(E)-ent-3beta-3,18-Dihydroxy-8(17),13-labdadien-15-oic acid
|
|
||||
|
C00022226
|
Henrilabdane A
/ (-)-Henrilabdane A |
|
||||
|
C00022227
|
(14S)-14,15-Dihydroxy-8(17),13(16)-labdadien-19-oic acid
|
|
||||
|
C00022249
|
(ent-13S)-15,16-Dihydroxy-8(17)-labden-18-oic acid
|
|
||||
|
C00022407
|
13S-Hydroxy-7,14-labdadien-19-oic acid
|
|
||||
|
C00022417
|
2alpha-Hydroxy-12Z-ozic acid
|
CHEMBL434755
|
|
|||
|
C00022418
|
2-Oxo-12Z-ozic acid
|
|
||||
|
C00022442
|
7,13(16)-Labdadiene-15,19-dioic acid
|
|
||||
|
C00022457
|
ent-Labda-8(17),13-dien-19-oic acid-15,16-olide
|
|
||||
|
C00022524
|
Viscidic acid A
/ ent-15-Hydroxy-8(17),13E-labdadien-18-oic acid |
CHEMBL511193
|
|
|||
|
C00022708
|
Isocupressic acid
/ (+)-Isocupressic acid / 15-Hydroxy-8(17),13E-labdadien-15-oic acid |
CHEMBL511193
|
C110793
|
|
||
|
C00022721
|
Torulosic acid
/ Cupressic acid / 13R-Hydroxy-8(17),14-labdadien-19-oic acid |
CHEMBL457163
|
|
|||
|
C00022722
|
13-Epicupressic acid
/ (+)-13-Epicupressic acid |
CHEMBL457163
|
|
|||
|
C00022768
|
7,13-Labdadien-15,16-olid-19-oic acid
|
|
||||
|
C00022769
|
ent-8(17),13-Labdadien-15,16-olid-18-oic acid
|
|
||||
|
C00022770
|
Pinusolidic acid
|
CHEMBL90504
CHEMBL465159 |
|
|||
|
C00023275
|
Isocommunic acid
/ Myrceocommunic acid |
|
||||
|
C00023283
|
Ozic acid
/ (-)-Ozic acid |
CHEMBL498097
CHEMBL1488779 CHEMBL1731589 |
13 / 14 / 8 |
|
||
|
C00023285
|
Communic acid
|
CHEMBL498097
CHEMBL1488779 CHEMBL1731589 |
13 / 14 / 8 |
|
||
|
C00023287
|
Z-Communic acid
/ Elliotinoic acid / (Z)-Communic acid / cis-Communic acid |
CHEMBL498097
CHEMBL1488779 CHEMBL1731589 |
13 / 14 / 8 |
|
||
|
C00023290
|
(13S)-7-Labdene-15,18-dioic acid
|
|
||||
|
C00023291
|
Pinifolic acid
|
CHEMBL2048915
|
|
|||
|
C00023300
|
Imbricatoloic acid
|
CHEMBL2048004
|
|
|||
|
C00023301
|
Acetylimbricatolic acid
|
|
||||
|
C00023303
|
Junicedric acid
|
CHEMBL2048915
|
|
|||
|
C00023304
|
Oliveric acid
|
CHEMBL2048915
|
|
|||
|
C00023344
|
Nivenolide
|
CHEMBL90504
CHEMBL465159 |
|
|||
|
C00023425
|
ent-15-Nor-14-oxo-8(17),12E-labdadiene-18-oic acid
|
CHEMBL497937
|
|
|||
|
C00023428
|
Acrostalic acid
|
|
||||
|
C00023429
|
LL-Z1271beta
|
CHEMBL1077022
CHEMBL2011788 |
|
|||
|
C00029408
|
16-Hydroxy communic acid
|
|
||||
|
C00031513
|
15-Methoxypinusolidic acid
/ (+)-15-Methoxypinusolidic acid |
|
||||
|
C00032600
|
14,15,-Bisnor-8(17)-labdene-16,19-dioic acid
|
|
||||
|
C00033908
|
Henrilabdane B
/ (-)-Henrilabdane B |
|
||||
|
C00033909
|
Henrilabdane C
/ (+)-Henrilabdane C |
|
||||
|
C00036233
|
trans-Communic acid
|
CHEMBL498097
CHEMBL1488779 CHEMBL1731589 |
13 / 14 / 8 |
|
||
|
C00038087
|
(+)-trans-Ozic acid
|
CHEMBL498097
CHEMBL1488779 CHEMBL1731589 |
13 / 14 / 8 |
|
||
|
C00040738
|
(-)-ent-trans-Communic acid
|
CHEMBL498097
CHEMBL1488779 CHEMBL1731589 |
13 / 14 / 8 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00023283 C00023285 C00023287 C00036233 C00038087 C00040738 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00023283 C00023285 C00023287 C00036233 C00038087 C00040738 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00023283 C00023285 C00023287 C00036233 C00038087 C00040738 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00023283 C00023285 C00023287 C00036233 C00038087 C00040738 | 7 / 3 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00023283 C00023285 C00023287 C00036233 C00038087 C00040738 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00023283 C00023285 C00023287 C00036233 C00038087 C00040738 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00023283 C00023285 C00023287 C00036233 C00038087 C00040738 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00023283 C00023285 C00023287 C00036233 C00038087 C00040738 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00023283 C00023285 C00023287 C00036233 C00038087 C00040738 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00023283 C00023285 C00023287 C00036233 C00038087 C00040738 | 4 / 3 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00023283 C00023285 C00023287 C00036233 C00038087 C00040738 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00023283 C00023285 C00023287 C00036233 C00038087 C00040738 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00023283 C00023285 C00023287 C00036233 C00038087 C00040738 | 2 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|