PCIDB

KCF-S cluster No. 1464 (7 metabolites)

Corresponding Phytochemical cluster No. 1

Plant Species

Cumulative plant class count

class name count
asterids 65
rosids 4

Cumulative family count

class name count
Solanaceae 65
Rhizophoraceae 4

KEGG BRITE br08003 External link 512

Categories (1)

br08003 Category # of metabolite
Tropane alkaloids 3

metabolites link (3)

br08003 Category KEGG ID KNApSAcK ID
Tropane alkaloids C12452 C00025551
Tropane alkaloids C12453 C00025556
Tropane alkaloids C10868 C00025557

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		figure
C00002304 External link 512 Tigloidine
CHEMBL2107120
CHEMBL2107196
C00025550 External link 512 Nortropine acetate
/ O-Acetylnortropine
/ 3alpha-Acetoxynortropane
C00025551 External link 512
/ Acetyltropine
/ Tropyl acetate
/ O-Acetyltropine
/ 3alpha-Acetoxytropane
/ Tropine acetate (ester)
/ Tropan-3a-ol acetate (ester)
/ endo-3-Acetoxy-8-methyl-8-azabicyclo[3.2.1]octane
CHEMBL193341
C071887
5 / 3 / 0
C00025553 External link 512 Butropine
/ 3alpha-Isobutyryloxytropane
C00025556 External link 512 3beta-Acetoxytropane
/ O-Acetylpseudotropine
CHEMBL193341
5 / 3 / 0
C00025557 External link 512 Tigloidin
/ Tigloyl pseudotropine
/ 3beta-Tigloyloxytropane
CHEMBL2107120
CHEMBL2107196
C00025559 External link 512 3-Tigloyloxynortropane

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00025551 C00025556 2 / 0
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00025551 C00025556 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00025551 C00025556 0 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00025551 C00025556 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00025551 C00025556 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#103780 Alcohol dependence P08172
#608516 Major depressive disorder; mdd P08172