KCF-S cluster No. 164 (35 metabolites)

Corresponding Phytochemical cluster No. 49

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (35)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Spermatophyta	55

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Cumulative family count

class name	count
Taxaceae	55

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Taxanes	2

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metabolites link (3)

br08003 Category	KEGG ID	KNApSAcK ID
Taxanes	C11700	C00035995
Taxanes	C11900	C00036790
Taxanes	C11900	C00040892

Metabolite list (35)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00031406	Tasumatrol O / (-)-Tasumatrol O
C00032599	13-O-Deacetyltaxumairol Z / (-)-13-O-Deacetyltaxumairol Z
C00033414	Taxumairol Z / (-)-Taxumairol Z
C00035995	10-Deacetylbaccatin III	CHEMBL335975 CHEMBL393912 CHEMBL1565880 CHEMBL1713307 CHEMBL1976896		6 / 4 / 1
C00036417	15-Benzoyl-10-deacetyl-2-debenzoyl-10-dehydro-abeo-baccatin III
C00036418	15-Benzoyl-7,9-dideacetyl-abeo-baccatin VI
C00036790	Baccatin III / (-)-Baccatin III	CHEMBL288043 CHEMBL1354786 CHEMBL1590876 CHEMBL2005552	C073950	10 / 17 / 16
C00040447	Tasumatrol V	CHEMBL504555
C00040448	Tasumatrol W	CHEMBL449791
C00040450	Tasumatrol Y	CHEMBL460248
C00040451	Tasumatrol Z	CHEMBL508812
C00040768	13-epi-10-Deacetylbaccatin III / (-)-13-epi-10-Deacetylbaccatin III	CHEMBL335975 CHEMBL393912 CHEMBL1565880 CHEMBL1713307 CHEMBL1976896		6 / 4 / 1
C00040769	14beta-Hydroxy-10-deacetylbaccatin III
C00040776	19-Hydroxybaccatin III	CHEMBL447792 CHEMBL503859	C031495
C00040844	7,9,10-Trideacetylbaccatin VI
C00040856	9-Dihydro-13-acetylbaccatin III	CHEMBL75533 CHEMBL1731226	C077498	4 / 1 / 0
C00040892	Baccatin V	CHEMBL288043 CHEMBL1354786 CHEMBL1590876 CHEMBL2005552		10 / 17 / 16
C00041147	Taxayuntin A
C00041148	Taxayuntin E	CHEMBL506577
C00041149	Taxayuntin F
C00041172	Taxuchin B
C00041185	Taxuspinanane C / (+)-Taxuspinanane C	CHEMBL77514
C00041189	Taxuspine E	CHEMBL436377 CHEMBL464306
C00042031	10-Deacetyl-10-oxobaccatin III	CHEMBL250045
C00042032	10-Deacetyl-13-oxobaccatin III / (-)-10-Deacetyl-13-oxobaccatin III	CHEMBL510651
C00042051	13-Dehydroxybaccatin III
C00042057	19-Hydroxy-10-deacetylbaccatin III	CHEMBL501666
C00043055	Tasumatrol E / (+)-Tasumatrol E	CHEMBL502734
C00043056	Tasumatrol F / (+)-Tasumatrol F	CHEMBL505278
C00043057	Tasumatrol G / (-)-Tasumatrol G	CHEMBL509227
C00043117	Wallifoliol / (-)-Wallifoliol	CHEMBL504343
C00043969	Taxuspinanane F / (-)-Taxuspinanane F	CHEMBL509211
C00045504	10-Deacetyl-10-oxo-baccatin V	CHEMBL250045
C00049530	Taxayuntin B
C00049536	Taxuspinanane D	CHEMBL265977

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00035995 C00036790 C00040768 C00040856 C00040892	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00035995 C00036790 C00040768 C00040856 C00040892	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00035995 C00036790 C00040768 C00040892	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00035995 C00040768 C00040856	1 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00035995 C00040768	1 / 1
Q99700	Ataxin-2	Unclassified protein	C00036790 C00040892	1 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00036790 C00040892	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00035995 C00040768	2 / 0
P02545	Prelamin-A/C	Unclassified protein	C00036790 C00040892	11 / 10
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00036790 C00040892	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00036790 C00040892	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00036790 C00040892	2 / 2
P28482	Mitogen-activated protein kinase 1	Erk	C00036790 C00040892	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00040856	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions