KCF-S cluster No. 1640 (6 metabolites)

Corresponding Phytochemical cluster No. 1

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (6)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Magnoliophyta	10

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Cumulative family count

class name	count
Piperaceae	10

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Piperidine alkaloids	1

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metabolites link (1)

br08003 Category	KEGG ID	KNApSAcK ID
Piperidine alkaloids	C10166	C00002066

Metabolite list (6)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002066	Piplartine / Piperlongumine	CHEMBL465843 CHEMBL1456697		28 / 44 / 65
C00002732	3'-Demethoxypiplartine
C00031305	Sarmentamide C
C00036572	4'-Desmethylpiplartine
C00036890	Cenocladamide
C00037055	Dihydropiplartine	CHEMBL1317639 CHEMBL1322597		6 / 14 / 43

Human Protein / Gene in interactions

29 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00002066 C00037055	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00002066 C00037055	7 / 37
P10636	Microtubule-associated protein tau	Unclassified protein	C00002066 C00037055	4 / 3
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002066 C00037055	3 / 3
P00352	Retinal dehydrogenase 1	Enzyme	C00002066 C00037055	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002066	1 / 0
P11473	Vitamin D3 receptor	NR1I1	C00002066	2 / 3
P02545	Prelamin-A/C	Unclassified protein	C00002066	11 / 10
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00002066	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00002066	2 / 0
O75496	Geminin	Unclassified protein	C00002066	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002066	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00002066	0 / 0
P42226	Signal transducer and activator of transcription 6	Unclassified protein	C00037055	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002066	0 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00002066	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002066	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00002066	1 / 1
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002066	1 / 1
O75030	Microphthalmia-associated transcription factor	Unclassified protein	C00002066	4 / 4
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002066	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002066	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002066	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00002066	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00002066	4 / 1
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002066	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002066	1 / 0
Q06710	Paired box protein Pax-8	Unclassified protein	C00002066	1 / 2
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00002066	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions