KCF-S cluster No. 1670 (6 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (6)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	14

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Cumulative family count

class name	count
Fabaceae	14

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (6)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002993	Haematoxylin	CHEMBL477197 CHEMBL1448387 CHEMBL1479103	D006416	70 / 83 / 92
C00010268	Brazilin	CHEMBL598951 CHEMBL1370456	C044362	32 / 25 / 25
C00020148	3'-O-Methylbrazilin	CHEMBL2207721
C00020149	3'-O-Methylsappanol
C00020152	4-O-Methylsappanol	CHEMBL477780		7 / 20 / 19
C00020451	Episappanol	CHEMBL477779		7 / 20 / 19

Human Protein / Gene in interactions

77 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P11362	Fibroblast growth factor receptor 1	Fgfr	C00002993 C00020152 C00020451	4 / 5
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00002993 C00020152 C00020451	0 / 0
P35968	Vascular endothelial growth factor receptor 2	Vegfr	C00002993 C00020152 C00020451	1 / 0
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00002993 C00020152 C00020451	2 / 3
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00002993 C00020152 C00020451	1 / 8
P10721	Mast/stem cell growth factor receptor Kit	Pdgfr	C00002993 C00020152 C00020451	4 / 3
P21802	Fibroblast growth factor receptor 2	TK tyrosine-protein kinase TLK subfamily	C00002993 C00020152 C00020451	9 / 3
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00002993 C00010268	2 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002993 C00010268	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00002993 C00010268	2 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002993 C00010268	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002993 C00010268	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002993 C00010268	4 / 3
O75164	Lysine-specific demethylase 4A	Enzyme	C00002993 C00010268	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002993 C00010268	0 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002993 C00010268	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00002993 C00010268	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002993 C00010268	2 / 2
Q99700	Ataxin-2	Unclassified protein	C00002993 C00010268	1 / 1
P11473	Vitamin D3 receptor	NR1I1	C00002993 C00010268	2 / 3
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00002993 C00010268	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002993 C00010268	3 / 3
P00352	Retinal dehydrogenase 1	Enzyme	C00002993 C00010268	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002993 C00010268	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00002993 C00010268	0 / 0
O00255	Menin	Unclassified protein	C00002993 C00010268	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002993 C00010268	1 / 2
O75496	Geminin	Unclassified protein	C00002993 C00010268	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002993 C00010268	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002993 C00010268	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00002993 C00010268	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00002993 C00010268	1 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002993	0 / 0
P49023	Paxillin	Unclassified protein	C00002993	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00002993	3 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00002993	0 / 0
P11308	Transcriptional regulator ERG	Unclassified protein	C00010268	1 / 2
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00010268	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00010268	0 / 0
P29323	Ephrin type-B receptor 2	Eph	C00002993	2 / 0
P04150	Glucocorticoid receptor	NR3C1	C00002993	0 / 1
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00002993	5 / 3
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00002993	5 / 9
P10145	Interleukin-8	Secreted protein	C00002993	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00010268	2 / 0
Q96RI1	Bile acid receptor	NR1H4	C00002993	0 / 0
P11413	Glucose-6-phosphate 1-dehydrogenase	Enzyme	C00002993	1 / 2
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002993	0 / 0
P10696	Alkaline phosphatase, placental-like	Enzyme	C00002993	0 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00002993	0 / 0
Q15078	Cyclin-dependent kinase 5 activator 1	REG serine/threonine protein kinase family	C00002993	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00002993	0 / 0
Q00535	Cyclin-dependent kinase 5	Cdk5	C00002993	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00010268	3 / 1
P16473	Thyrotropin receptor	Glycohormone receptor	C00002993	3 / 2
Q9UNA4	DNA polymerase iota	Enzyme	C00002993	0 / 0
P14735	Insulin-degrading enzyme	Enzyme	C00010268	0 / 0
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00002993	0 / 0
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00002993	1 / 4
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002993	1 / 1
P10275	Androgen receptor	NR3C4	C00002993	3 / 4
P04062	Glucosylceramidase	Enzyme	C00002993	6 / 4
P34949	Mannose-6-phosphate isomerase	Enzyme	C00002993	1 / 1
P06746	DNA polymerase beta	Enzyme	C00002993	0 / 0
Q14145	Kelch-like ECH-associated protein 1	Unclassified protein	C00010268	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00002993	2 / 2
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00002993	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002993	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002993	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002993	1 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00002993	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00002993	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00002993	4 / 1
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002993	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002993	1 / 4
Q07820	Induced myeloid leukemia cell differentiation protein Mcl-1	Other cytosolic protein	C00002993	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00002993	7 / 37

Related Diseases

Diseases related to proteins in ChEMBL interactions