KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00001264 External link 512 Octanol
/ n-Octanol
/ 1-Octanol
/ Octan-1-ol
CHEMBL26215
D020003
5 / 6 / 5 2 / 0
C00030830 External link 512 Nonanol
/ n-Nonanol
CHEMBL24563
C014713
1 / 0
C00034882 External link 512 Nonane
/ n-Nonane
CHEMBL335900
C017573
1 / 3 / 2 3 / 2
C00035700 External link 512 n-Heptanol
CHEMBL273459
D019850
1 / 0
C00035857 External link 512 Octane
/ n-Octane
CHEMBL134886
C026728
C00048375 External link 512 Decane
CHEMBL134537
C012867
2 / 1

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P16473 Thyrotropin receptor Glycohormone receptor C00034882 3 / 2
P10828 Thyroid hormone receptor beta NR1A2 C00001264 3 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00001264 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00001264 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00001264 0 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001264 3 / 3

6 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00034882 C00048375
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00034882 C00048375
1080 CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) C00001264 C00035700
5241 PGR, NR3C3, PR progesterone receptor C00034882
9970 NR1I3, CAR, CAR1, MB67 nuclear receptor subfamily 1, group I, member 3 C00030830
128 ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284) C00001264

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (7)

KEGG name UniProt
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D004890 Erythema C00048375
C00034882
D017453 Dermatitis, Irritant C00034882