KCF-S cluster No. 179 (34 metabolites)

Corresponding Phytochemical cluster No. 15

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (34)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
Liliopsida	27
rosids	23
asterids	2
Embryophyta	2
Euphyllophyta	1

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Cumulative family count

class name	count
Asparagaceae	14
Fabaceae	14
Amaryllidaceae	10
Moraceae	6
Meliaceae	3
Rubiaceae	2
Xanthorrhoeaceae	2
Corsiniaceae	2
Dennstaedtiaceae	1
Arecaceae	1

KEGG BRITE br08003

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Categories (2)

br08003 Category	# of metabolite
Flavans	5
Isoflavanes	1

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metabolites link (7)

br08003 Category	KEGG ID	KNApSAcK ID
Flavans	C09505	C00000943
Flavans	C09641	C00000950
Flavans	C09646	C00000952
Flavans	C09650	C00000953
Flavans	C09757	C00000971
Isoflavanes	C14131	C00009707
Flavans	C09641	C00045487

Metabolite list (34)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00000943	Broussin	CHEMBL253563
C00000950	Cassiaflavan / 7,4'-Dihydroxyflavan	CHEMBL508033 CHEMBL463804 CHEMBL463168		4 / 3 / 3
C00000952	7,3'-Dihydroxy-4'-methoxy-8-methylflavan
C00000953	7,4'-Dihydroxy-8-methylflavan	CHEMBL251978 CHEMBL1077942
C00000971	7-Hydroxyflavan
C00008750	7-Hydroxy-5-methoxyflavan	CHEMBL451419
C00008751	Tephrowatsin E
C00008752	4'-Hydroxy-7-methoxyflavan	CHEMBL1080979
C00008753	Apigeniflavan	CHEMBL471590
C00008754	5,7-Dihydroxy-4'-methoxyflavan
C00008758	3',4'-Dihydroxy-7-methoxyflavan
C00008759	7,4'-Dihydroxy-3'-methoxyflavan
C00008760	7,3'-Dihydroxy-4'-methoxyflavan	CHEMBL2017115
C00008779	7,4'-Dihydroxy-3'-methoxy-8-methylflavan
C00008780	5,4'-Dihydroxy-7'-methoxy-8-methylflavan	CHEMBL253562
C00008781	4'-Hydroxy-5,7-dimethoxy-8-methylflavan
C00008782	4'-Hydroxy-7-methoxy-8-methylflavan	CHEMBL263832
C00008783	7-Hydroxy-5-methoxy-6-methylflavan
C00008804	Epidistenin
C00009357	Guibourtinidol / (2R,3S)-4',7-Dihydroxyflavan-3-ol
C00009707	Equol / 7,4'-Dihydroxyisoflavan	CHEMBL198877 CHEMBL1957037
C00013245	Tupichinol C / (R)-3,4-Dihydro-2-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol	CHEMBL508033 CHEMBL463804 CHEMBL463168		4 / 3 / 3
C00013260	Guibourtinidol-7-methyl ether
C00013261	Tupichinol A / (2R,3R)-3,4-Dihydro-2-(4-hydroxyphenyl)-7-methoxy-8-methyl-2H-1-benzopyran-3-ol	CHEMBL464202
C00019227	Corsifuran A / 5,4'-Dimethoxy-2,3-dihydro-2-arylbenzofuran
C00019228	Corsifuran B / 5-Hydroxy-4'-methoxy-2,3-dihydro-2-arylbenzofuran
C00020660	Obtusafuran	CHEMBL454468
C00032429	Tupichinol D / (-)-Tupichinol D
C00036525	3',7-Dihydroxy-4'-methoxyflavan	CHEMBL2017115
C00038096	(2S)-4',5-Dihydroxy-7-methoxy-8-methylflavan	CHEMBL253562
C00040792	2,4-trans-7,4'-Dihydroxy-4-methoxyflavan
C00045130	Tupichinol B
C00045487	(2S)-7,4'-Dihydroxyflavan	CHEMBL508033 CHEMBL463804 CHEMBL463168		4 / 3 / 3
C00045615	Acutifolin F / (-)-Acutifolin F

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P14555	Phospholipase A2, membrane associated	Enzyme	C00000950 C00013245 C00045487	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000950 C00013245 C00045487	0 / 1
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00000950 C00013245 C00045487	2 / 2
P03372	Estrogen receptor	NR3A1	C00000950 C00013245 C00045487	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions