KCF-S cluster No. 1800 (6 metabolites)
Corresponding Phytochemical cluster No. 4
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| asterids | 21 |
Cumulative family count
| class name | count |
|---|---|
| Apocynaceae | 20 |
| Loganiaceae | 1 |
KEGG BRITE br08003
Categories (1)
| br08003 Category | # of metabolite |
|---|---|
| Indole alkaloids | 1 |
metabolites link (1)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|---|---|
| Indole alkaloids | C09025 | C00001680 |
Metabolite list (6)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00001680
|
(-)-Akuammicine:Akuammicine
|
CHEMBL508955
|
|
|||
|
C00025822
|
Condylocarpine
/ (+)-Condylocarpine |
|
||||
|
C00025960
|
Norfluorocurarine
/ C-Norcurarine III / nor-C-Fluorocurarine / (-)-Norfluorocurarine |
CHEMBL1395099
|
5 / 6 / 11 |
|
||
|
C00026077
|
Vincanidine
|
|
||||
|
C00027078
|
11-Methoxyakuammicine
|
|
||||
|
C00027671
|
12-Hydroxy-11-methoxynor-C-fluorocurarine
|
|
Human Protein / Gene in interactions
5 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P11473 | Vitamin D3 receptor | NR1I1 | C00025960 | 2 / 3 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00025960 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00025960 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00025960 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00025960 | 1 / 2 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (6)
| OMIM | preferred title | UniProt |
|---|---|---|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (11)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|