KCF-S cluster No. 1817 (6 metabolites)

Corresponding Phytochemical cluster No. 41

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (6)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	8

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Cumulative family count

class name	count
Euphorbiaceae	7
Thymelaeaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Tiglianes	5

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metabolites link (5)

br08003 Category	KEGG ID	KNApSAcK ID
Tiglianes	C09086	C00003422
Tiglianes	C09153	C00003464
Tiglianes	C09157	C00003466
Tiglianes	C05151	C00003491
Tiglianes	C20197	C00040076

Metabolite list (6)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00003422	Diterpenoid EF-D	CHEMBL520853
C00003464	12-O-Palmitoyl-16-hydroxyphorbol 13-acetate	CHEMBL2012888	C028113
C00003466	Phorbol 12-tiglate 13-decanoate		C011986
C00003491	12-Tetradecanoylphorbol 13-acetate	CHEMBL291793 CHEMBL279115 CHEMBL1328542 CHEMBL1441758 CHEMBL1443384 CHEMBL1446902 CHEMBL1515083	D013755	57 / 57 / 76	471 / 23
C00040076	Prostratin	CHEMBL170518 CHEMBL1980156	C070999	9 / 2 / 2
C00044231	Mellerin A / (+)-Mellerin A

Human Protein / Gene in interactions

57 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q15139	Serine/threonine-protein kinase D1	Pkd	C00003491 C00040076	0 / 0
P24723	Protein kinase C eta type	Eta	C00003491 C00040076	1 / 0
O94806	Serine/threonine-protein kinase D3	Pkd	C00003491 C00040076	0 / 0
P05771	Protein kinase C beta type	Alpha	C00003491 C00040076	0 / 0
P05129	Protein kinase C gamma type	Alpha	C00003491 C00040076	1 / 1
Q02156	Protein kinase C epsilon type	Eta	C00003491 C00040076	0 / 0
Q04759	Protein kinase C theta type	Delta	C00003491 C00040076	0 / 1
Q05655	Protein kinase C delta type	Delta	C00003491 C00040076	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00003491 C00040076	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00003491	1 / 1
P21728	D(1A) dopamine receptor	Dopamine receptor	C00003491	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00003491	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00003491	11 / 10
P16473	Thyrotropin receptor	Glycohormone receptor	C00003491	3 / 2
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003491	2 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003491	0 / 1
P54132	Bloom syndrome protein	Enzyme	C00003491	1 / 2
P00352	Retinal dehydrogenase 1	Enzyme	C00003491	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00003491	0 / 0
O75496	Geminin	Unclassified protein	C00003491	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00003491	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00003491	1 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00003491	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00003491	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00003491	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00003491	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00003491	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00003491	3 / 3
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00003491	2 / 2
Q01453	Peripheral myelin protein 22	Unclassified protein	C00003491	5 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00003491	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00003491	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00003491	4 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003491	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003491	0 / 1
Q8IV61	Ras guanyl-releasing protein 3	Other cytosolic protein	C00003491	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00003491	0 / 0
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00003491	1 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00003491	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00003491	4 / 3
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00003491	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00003491	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00003491	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00003491	1 / 1
O00167	Eyes absent homolog 2	Enzyme	C00003491	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00003491	0 / 0
O95267	RAS guanyl-releasing protein 1	Unclassified protein	C00003491	1 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00003491	1 / 1
O00255	Menin	Unclassified protein	C00003491	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00003491	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00003491	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00003491	1 / 4
Q05513	Protein kinase C zeta type	Iota	C00003491	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00003491	7 / 37
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00003491	0 / 0
P41743	Protein kinase C iota type	Iota	C00003491	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003491	1 / 0

471 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5244	ABCB4, ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3	ATP-binding cassette, sub-family B (MDR/TAP), member 4 (EC:3.6.3.44)	C00003491
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00003491
10257	ABCC4, EST170205, MOAT-B, MOATB, MRP4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	C00003491
1636	ACE, ACE1, CD143, DCP, DCP1, ICH, MVCD3	angiotensin I converting enzyme (EC:3.4.15.1)	C00003491
60	ACTB, BRWS1, PS1TP5BP1	actin, beta	C00003491
8038	ADAM12, MCMP, MCMPMltna, MLTN, MLTNA	ADAM metallopeptidase domain 12	C00003491
101	ADAM8, CD156, MS2	ADAM metallopeptidase domain 8 (EC:3.4.24.-)	C00003491
154	ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR	adrenoceptor beta 2, surface	C00003491
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00003491
37815			C00003491
11199	ANXA10, ANX14	annexin A10	C00003491
306	ANXA3, ANX3	annexin A3 (EC:3.1.4.43)	C00003491
317	APAF1, APAF-1, CED4	apoptotic peptidase activating factor 1	C00003491
27301	APEX2, APE2, APEXL2, XTH2	APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (EC:4.2.99.18)	C00003491
334	APLP2, APLP-2, APPH, APPL2, CDEBP	amyloid beta (A4) precursor-like protein 2	C00003491
374	AREG, AR, CRDGF, SDGF	amphiregulin	C00003491
375	ARF1	ADP-ribosylation factor 1	C00003491
382	ARF6	ADP-ribosylation factor 6	C00003491
23229	ARHGEF9, COLLYBISTIN, EIEE8, HPEM-2, PEM-2, PEM2	Cdc42 guanine nucleotide exchange factor (GEF) 9	C00003491
10123	ARL4C, ARL7, LAK	ADP-ribosylation factor-like 4C	C00003491
10550	ARL6IP5, DERP11, GTRAP3-18, JWA, PRAF3, addicsin, hp22, jmx	ADP-ribosylation-like factor 6 interacting protein 5	C00003491
10109	ARPC2, ARC34, PNAS-139, p34-Arc	actin related protein 2/3 complex, subunit 2, 34kDa	C00003491
445	ASS1, ASS, CTLN1	argininosuccinate synthase 1 (EC:6.3.4.5)	C00003491
468	ATF4, CREB-2, CREB2, TAXREB67, TXREB	activating transcription factor 4	C00003491
22809	ATF5, ATFX, HMFN0395	activating transcription factor 5	C00003491
538	ATP7A, DSMAX, MK, MNK, SMAX3	ATPase, Cu++ transporting, alpha polypeptide (EC:3.6.3.54)	C00003491
540	ATP7B, PWD, WC1, WD, WND	ATPase, Cu++ transporting, beta polypeptide (EC:3.6.3.54)	C00003491
6790	AURKA, AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7	aurora kinase A (EC:2.7.11.1)	C00003491
573	BAG1, BAG-1, HAP, RAP46	BCL2-associated athanogene	C00003491
578	BAK1, BAK, BAK-LIKE, BCL2L7, CDN1	BCL2-antagonist/killer 1	C00003491
581	BAX, BCL2L4	BCL2-associated X protein	C00003491
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00003491
597	BCL2A1, ACC-1, ACC-2, BCL2L5, BFL1, GRS, HBPA1	BCL2-related protein A1	C00003491
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00003491
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00003491
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00003491
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00003491
650	BMP2, BDA2, BMP2A	bone morphogenetic protein 2	C00003491
682	BSG, 5F7, CD147, EMMPRIN, M6, OK, TCSF	basigin	C00003491
7832	BTG2, PC3, TIS21	BTG family, member 2	C00003491
701	BUB1B, BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1	BUB1 mitotic checkpoint serine/threonine kinase B (EC:2.7.11.1)	C00003491
23632	CA14, CAXiV	carbonic anhydrase XIV (EC:4.2.1.1)	C00003491
811	CALR, CRT, RO, SSA, cC1qR	calreticulin	C00003491
8536	CAMK1, CAMKI	calcium/calmodulin-dependent protein kinase I (EC:2.7.11.17)	C00003491
11131	CAPN11, calpain11	calpain 11	C00003491
10753	CAPN9, GC36, nCL-4	calpain 9 (EC:3.4.22.-)	C00003491
834	CASP1, ICE, IL1BC, P45	caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36)	C00003491
100506742	CASP12, CASP-12, CASP12P1	caspase 12 (gene/pseudogene)	C00003491
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00003491
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00003491
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00003491
847	CAT	catalase (EC:1.11.1.6)	C00003491
6346	CCL1, I-309, P500, SCYA1, SISe, TCA3	chemokine (C-C motif) ligand 1	C00003491
6356	CCL11, SCYA11	chemokine (C-C motif) ligand 11	C00003491
6362	CCL18, AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	C00003491
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00003491
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00003491
6349	CCL3L1, 464.2, D17S1718, G0S19-2, LD78, LD78BETA, MIP1AP, SCYA3L, SCYA3L1	chemokine (C-C motif) ligand 3-like 1	C00003491
6351	CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4	chemokine (C-C motif) ligand 4	C00003491
9560	CCL4L1, AT744.2, CCL4L, LAG-1, LAG1, SCYA4L	chemokine (C-C motif) ligand 4-like 1	C00003491
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00003491
890	CCNA2, CCN1, CCNA	cyclin A2	C00003491
9133	CCNB2, HsT17299	cyclin B2	C00003491
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00003491
896	CCND3	cyclin D3	C00003491
898	CCNE1, CCNE	cyclin E1	C00003491
900	CCNG1, CCNG	cyclin G1	C00003491
22948	CCT5, CCT-epsilon, CCTE, TCP-1-epsilon	chaperonin containing TCP1, subunit 5 (epsilon)	C00003491
100136148			C00003491
929	CD14	CD14 molecule	C00003491
4345	CD200, MOX1, MOX2, MRC, OX-2	CD200 molecule	C00003491
940	CD28, Tp44	CD28 molecule	C00003491
947	CD34	CD34 molecule	C00003491
948	CD36, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3	CD36 molecule (thrombospondin receptor)	C00003491
920	CD4, CD4mut	CD4 molecule	C00003491
958	CD40, Bp50, CDW40, TNFRSF5, p50	CD40 molecule, TNF receptor superfamily member 5	C00003491
959	CD40LG, CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L	CD40 ligand	C00003491
960	CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1	CD44 molecule (Indian blood group)	C00003491
965	CD58, LFA-3, LFA3, ag3	CD58 molecule	C00003491
969	CD69, AIM, BL-AC/P26, CLEC2C, EA1, GP32/28, MLR-3	CD69 molecule	C00003491
928	CD9, BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29	CD9 molecule	C00003491
991	CDC20, CDC20A, bA276H19.3, p55CDC	cell division cycle 20	C00003491
994	CDC25B	cell division cycle 25B (EC:3.1.3.48)	C00003491
995	CDC25C, CDC25, PPP1R60	cell division cycle 25C (EC:3.1.3.48)	C00003491
1015	CDH17, CDH16, HPT-1, HPT1	cadherin 17, LI cadherin (liver-intestine)	C00003491
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00003491
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00003491
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00003491
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00003491
1028	CDKN1C, BWCR, BWS, KIP2, WBS, p57, p57Kip2	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	C00003491
1029	CDKN2A, ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16	cyclin-dependent kinase inhibitor 2A	C00003491
1030	CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	C00003491
1031	CDKN2C, INK4C, p18, p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	C00003491
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00003491
1164	CKS2, CKSHS2	CDC28 protein kinase regulatory subunit 2	C00003491
1364	CLDN4, CPE-R, CPER, CPETR, CPETR1, WBSCR8, hCPE-R	claudin 4	C00003491
1201	CLN3, BTS, JNCL	ceroid-lipofuscinosis, neuronal 3	C00003491
8418	CMAHP, CMAH, CSAH	cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene	C00003491
1240	CMKLR1, CHEMERINR, ChemR23, DEZ, RVER1	chemokine-like receptor 1	C00003491
1264	CNN1, SMCC, Sm-Calp	calponin 1, basic, smooth muscle	C00003491
27255	CNTN6, NB3	contactin 6	C00003491
1278	COL1A2, OI4	collagen, type I, alpha 2	C00003491
1291	COL6A1, OPLL	collagen, type VI, alpha 1	C00003491
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00003491
4513	COX2, COII, MTCO2, MT-CO2	cytochrome c oxidase subunit II	C00003491
1385	CREB1, CREB	cAMP responsive element binding protein 1	C00003491
1387	CREBBP, CBP, KAT3A, RSTS	CREB binding protein (EC:2.3.1.48)	C00003491
1390	CREM, CREM-2, ICER, hCREM-2	cAMP responsive element modulator	C00003491
56253	CRTAM, CD355	cytotoxic and regulatory T cell molecule	C00003491
1407	CRY1, PHLL1	cryptochrome 1 (photolyase-like)	C00003491
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00003491
1440	CSF3, C17orf33, CSF3OS, GCSF, G-CSF	colony stimulating factor 3 (granulocyte)	C00003491
1487	CTBP1, BARS	C-terminal binding protein 1	C00003491
8065	CUL5, VACM-1, VACM1	cullin 5	C00003491
6376	CX3CL1, ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin	chemokine (C-X3-C motif) ligand 1	C00003491
6387	CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B	chemokine (C-X-C motif) ligand 12	C00003491
6374	CXCL5, ENA-78, SCYB5	chemokine (C-X-C motif) ligand 5	C00003491
6372	CXCL6, CKA-3, GCP-2, GCP2, SCYB6	chemokine (C-X-C motif) ligand 6	C00003491
3577	CXCR1, C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA	chemokine (C-X-C motif) receptor 1	C00003491
3579	CXCR2, CD182, CDw128b, CMKAR2, IL8R2, IL8RA, IL8RB	chemokine (C-X-C motif) receptor 2	C00003491
1535	CYBA, p22-PHOX	cytochrome b-245, alpha polypeptide	C00003491
1536	CYBB, AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX	cytochrome b-245, beta polypeptide	C00003491
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00003491
1585	CYP11B2, ALDOS, CPN2, CYP11B, CYP11BL, CYPXIB2, P-450C18, P450C18, P450aldo	cytochrome P450, family 11, subfamily B, polypeptide 2 (EC:1.14.15.4 1.14.15.5)	C00003491
1588	CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM	cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00003491
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00003491
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00003491
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00003491
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00003491
1581	CYP7A1, CP7A, CYP7, CYPVII	cytochrome P450, family 7, subfamily A, polypeptide 1 (EC:1.14.13.17)	C00003491
1612	DAPK1, DAPK	death-associated protein kinase 1 (EC:2.7.11.1)	C00003491
1638	DCT, TRP-2, TYRP2	dopachrome tautomerase (EC:5.3.3.12)	C00003491
1735	DIO3, 5DIII, D3, DIOIII, TXDI3	deiodinase, iodothyronine, type III (EC:1.97.1.11)	C00003491
8788	DLK1, DLK, DLK-1, Delta1, FA1, PREF1, Pref-1, ZOG, pG2	delta-like 1 homolog (Drosophila)	C00003491
1806	DPYD, DHP, DHPDHASE, DPD	dihydropyrimidine dehydrogenase (EC:1.3.1.2)	C00003491
1843	DUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10	dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48)	C00003491
51207	DUSP13, BEDP, DUSP13A, DUSP13B, MDSP, SKRP4, TMDP	dual specificity phosphatase 13 (EC:3.1.3.16 3.1.3.48)	C00003491
1846	DUSP4, HVH2, MKP-2, MKP2, TYP	dual specificity phosphatase 4 (EC:3.1.3.16 3.1.3.48)	C00003491
1874	E2F4, E2F-4	E2F transcription factor 4, p107/p130-binding	C00003491
8411	EEA1, MST105, MSTP105, ZFYVE2	early endosome antigen 1	C00003491
1945	EFNA4, EFL4, EPLG4, LERK4	ephrin-A4	C00003491
1950	EGF, HOMG4, URG	epidermal growth factor	C00003491
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003491
1958	EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225	early growth response 1	C00003491
1959	EGR2, AT591, CMT1D, CMT4E, KROX20	early growth response 2	C00003491
1961	EGR4, NGFI-C, NGFIC, PAT133	early growth response 4	C00003491
1977	EIF4E, AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F	eukaryotic translation initiation factor 4E	C00003491
1978	EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I	eukaryotic translation initiation factor 4E binding protein 1	C00003491
1981	EIF4G1, EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18	eukaryotic translation initiation factor 4 gamma, 1	C00003491
1982	EIF4G2, AAG1, DAP5, NAT1, P97	eukaryotic translation initiation factor 4 gamma, 2	C00003491
1983	EIF5, EIF-5, EIF-5A	eukaryotic translation initiation factor 5	C00003491
2002	ELK1	ELK1, member of ETS oncogene family	C00003491
2021	ENDOG	endonuclease G	C00003491
2064	ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN_19, NEU, NGL, TKR1	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1)	C00003491
2066	ERBB4, ALS19, HER4, p180erbB4	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 (EC:2.7.10.1)	C00003491
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00003491
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00003491
2152	F3, CD142, TF, TFA	coagulation factor III (thromboplastin, tissue factor)	C00003491
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00003491
2237	FEN1, FEN-1, MF1, RAD2	flap structure-specific endonuclease 1	C00003491
8823	FGF16, FGF-16, MF4	fibroblast growth factor 16	C00003491
2247	FGF2, BFGF, FGF-2, FGFB, HBGF-2	fibroblast growth factor 2 (basic)	C00003491
2289	FKBP5, AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10	FK506 binding protein 5 (EC:5.2.1.8)	C00003491
2321	FLT1, FLT, FLT-1, VEGFR-1, VEGFR1	fms-related tyrosine kinase 1 (EC:2.7.10.1)	C00003491
2330	FMO5	flavin containing monooxygenase 5 (EC:1.14.13.8)	C00003491
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00003491
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00003491
2354	FOSB, AP-1, G0S3, GOS3, GOSB	FBJ murine osteosarcoma viral oncogene homolog B	C00003491
8061	FOSL1, FRA, FRA1, fra-1	FOS-like antigen 1	C00003491
2355	FOSL2, FRA2	FOS-like antigen 2	C00003491
2309	FOXO3, AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A	forkhead box O3	C00003491
2533	FYB, ADAP, PRO0823, SLAP-130	FYN binding protein	C00003491
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00003491
2623	GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT	GATA binding protein 1 (globin transcription factor 1)	C00003491
2624	GATA2, DCML, MONOMAC, NFE1B	GATA binding protein 2	C00003491
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00003491
2662	GDF10, BMP-3b, BMP3B	growth differentiation factor 10	C00003491
2672	GFI1, GFI-1, GFI1A, SCN2, ZNF163	growth factor independent 1 transcription repressor	C00003491
2675	GFRA2, GDNFRB, NRTNR-ALPHA, NTNRA, RETL2, TRNR2	GDNF family receptor alpha 2	C00003491
2694	GIF, IF, IFMH, INF, TCN3	gastric intrinsic factor (vitamin B synthesis)	C00003491
2697	GJA1, AVSD3, CMDR, CX43, DFNB38, GJAL, HLHS1, HSS, ODDD	gap junction protein, alpha 1, 43kDa	C00003491
10578	GNLY, 519, D2S69E, LAG-2, LAG2, NKG5, TLA519	granulysin	C00003491
2798	GNRHR, GNRHR1, GRHR, HH7, LHRHR, LRHR	gonadotropin-releasing hormone receptor	C00003491
2876	GPX1, GPXD, GSHPX1	glutathione peroxidase 1 (EC:1.11.1.9)	C00003491
2879	GPX4, GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx	glutathione peroxidase 4 (EC:1.11.1.12)	C00003491
2896	GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN	granulin	C00003491
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00003491
2968	GTF2H4, P52, TFB2, TFIIH	general transcription factor IIH, polypeptide 4, 52kDa	C00003491
2993	GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2	glycophorin A (MNS blood group)	C00003491
3030	HADHA, ECHA, GBP, HADH, LCEH, LCHAD, MTPA, TP-ALPHA	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211)	C00003491
3035	HARS, HRS, USH3B	histidyl-tRNA synthetase (EC:6.1.1.21)	C00003491
1839	HBEGF, DTR, DTS, DTSF, HEGFL	heparin-binding EGF-like growth factor	C00003491
3055	HCK, JTK9, p59Hck, p61Hck	hemopoietic cell kinase (EC:2.7.10.2)	C00003491
3067	HDC	histidine decarboxylase (EC:4.1.1.22)	C00003491
3082	HGF, DFNB39, F-TCF, HGFB, HPTA, SF	hepatocyte growth factor (hepapoietin A; scatter factor)	C00003491
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00003491
3146	HMGB1, HMG1, HMG3, SBP-1	high mobility group box 1	C00003491
3156	HMGCR, LDLCQ3	3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34)	C00003491
3157	HMGCS1, HMGCS	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) (EC:2.3.3.10)	C00003491
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00003491
3248	HPGD, 15-PGDH, PGDH, PGDH1, PHOAR1, SDR36C1	hydroxyprostaglandin dehydrogenase 15-(NAD) (EC:1.1.1.141)	C00003491
3265	HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1	Harvey rat sarcoma viral oncogene homolog	C00003491
3306	HSPA2, HSP70-2, HSP70-3	heat shock 70kDa protein 2	C00003491
3310	HSPA6	heat shock 70kDa protein 6 (HSP70B')	C00003491
3312	HSPA8, HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP1, NIP71	heat shock 70kDa protein 8	C00003491
3313	HSPA9, CSA, GRP-75, GRP75, HSPA9B, MOT, MOT2, MTHSP75, PBP74	heat shock 70kDa protein 9 (mortalin)	C00003491
3381	IBSP, BNSP, BSP, BSP-II, SP-II	integrin-binding sialoprotein	C00003491
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00003491
3458	IFNG, IFG, IFI	interferon, gamma	C00003491
3460	IFNGR2, AF-1, IFGR2, IFNGT1	interferon gamma receptor 2 (interferon gamma transducer 1)	C00003491
3488	IGFBP5, IBP5	insulin-like growth factor binding protein 5	C00003491
3490	IGFBP7, AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF	insulin-like growth factor binding protein 7	C00003491
3543	IGLL1, 14.1, AGM2, CD179b, IGL1, IGL5, IGLJ14.1, IGLL, IGO, IGVPB, VPREB2	immunoglobulin lambda-like polypeptide 1	C00003491
3551	IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)	C00003491
8517	IKBKG, AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IP, IP1, IP2, IPD2, NEMO, ZC2HC9	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	C00003491
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00003491
3589	IL11, AGIF, IL-11	interleukin 11	C00003491
3593	IL12B, CLMF, CLMF2, IL-12B, NKSF, NKSF2	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	C00003491
3594	IL12RB1, CD212, IL-12R-BETA1, IL12RB	interleukin 12 receptor, beta 1	C00003491
3595	IL12RB2	interleukin 12 receptor, beta 2	C00003491
3596	IL13, IL-13, P600	interleukin 13	C00003491
8809	IL18R1, CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP	interleukin 18 receptor 1	C00003491
3552	IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1	interleukin 1, alpha	C00003491
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00003491
3554	IL1R1, CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80	interleukin 1 receptor, type I	C00003491
7850	IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB	interleukin 1 receptor, type II	C00003491
3556	IL1RAP, C3orf13, IL-1RAcP, IL1R3	interleukin 1 receptor accessory protein	C00003491
26280	IL1RAPL2, IL-1R9, IL1R9, IL1RAPL-2, TIGIRR-1	interleukin 1 receptor accessory protein-like 2	C00003491
3557	IL1RN, DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4	interleukin 1 receptor antagonist	C00003491
3558	IL2, IL-2, TCGF, lymphokine	interleukin 2	C00003491
3559	IL2RA, CD25, IDDM10, IL2R, TCGFR	interleukin 2 receptor, alpha	C00003491
3560	IL2RB, CD122, IL15RB, P70-75	interleukin 2 receptor, beta	C00003491
3562	IL3, IL-3, MCGF, MULTI-CSF	interleukin 3 (colony-stimulating factor, multiple)	C00003491
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00003491
3567	IL5, EDF, IL-5, TRF	interleukin 5 (colony-stimulating factor, eosinophil)	C00003491
3568	IL5RA, CD125, CDw125, HSIL5R3, IL5R	interleukin 5 receptor, alpha	C00003491
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00003491
3570	IL6R, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80	interleukin 6 receptor	C00003491
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00003491
3581	IL9R, CD129, IL-9R	interleukin 9 receptor	C00003491
11213	IRAK3, ASRT5, IRAKM	interleukin-1 receptor-associated kinase 3 (EC:2.7.11.1)	C00003491
3662	IRF4, LSIRF, MUM1, NF-EM5	interferon regulatory factor 4	C00003491
3673	ITGA2, BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	C00003491
3674	ITGA2B, BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	C00003491
3684	ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6	integrin, alpha M (complement component 3 receptor 3 subunit)	C00003491
3687	ITGAX, CD11C, SLEB6	integrin, alpha X (complement component 3 receptor 4 subunit)	C00003491
3689	ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	C00003491
3690	ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	C00003491
3694	ITGB6	integrin, beta 6	C00003491
3713	IVL	involucrin	C00003491
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00003491
3726	JUNB, AP-1	jun B proto-oncogene	C00003491
3727	JUND, AP-1	jun D proto-oncogene	C00003491
3752	KCND3, KCND3L, KCND3S, KSHIVB, KV4.3, SCA19, SCA22	potassium voltage-gated channel, Shal-related subfamily, member 3	C00003491
10112	KIF20A, MKLP2, RAB6KIFL	kinesin family member 20A	C00003491
9585	KIF20B, CT90, KRMP1, MPHOSPH1, MPP-1, MPP1	kinesin family member 20B	C00003491
9493	KIF23, CHO1, KNSL5, MKLP-1, MKLP1	kinesin family member 23	C00003491
11004	KIF2C, KNSL6, MCAK	kinesin family member 2C	C00003491
11278	KLF12, AP-2rep, AP2REP	Kruppel-like factor 12	C00003491
9314	KLF4, EZF, GKLF	Kruppel-like factor 4 (gut)	C00003491
1316	KLF6, BCD1, CBA1, COPEB, CPBP, GBF, PAC1, ST12, ZF9	Kruppel-like factor 6	C00003491
3845	KRAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2	Kirsten rat sarcoma viral oncogene homolog	C00003491
3912	LAMB1, CLM, LIS5	laminin, beta 1	C00003491
3936	LCP1, CP64, L-PLASTIN, LC64P, LPL, PLS2	lymphocyte cytosolic protein 1 (L-plastin)	C00003491
3976	LIF, CDF, DIA, HILDA, MLPLI	leukemia inhibitory factor	C00003491
4005	LMO2, RBTN2, RBTNL1, RHOM2, TTG2	LIM domain only 2 (rhombotin-like 1)	C00003491
4008	LMO7, FBX20, FBXO20, LOMP	LIM domain 7	C00003491
4023	LPL, HDLCQ11, LIPD	lipoprotein lipase (EC:3.1.1.34)	C00003491
4035	LRP1, A2MR, APOER, APR, CD91, IGFBP3R, LRP, LRP1A, TGFBR5	low density lipoprotein receptor-related protein 1	C00003491
8425	LTBP4, ARCL1C, LTBP-4, LTBP4L, LTBP4S	latent transforming growth factor beta binding protein 4	C00003491
8379	MAD1L1, MAD1, PIG9, TP53I9, TXBP181	MAD1 mitotic arrest deficient-like 1 (yeast)	C00003491
4085	MAD2L1, HSMAD2, MAD2	MAD2 mitotic arrest deficient-like 1 (yeast)	C00003491
81631	MAP1LC3B, ATG8F, LC3B, MAP1A/1BLC3, MAP1LC3B-a	microtubule-associated protein 1 light chain 3 beta	C00003491
5604	MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1	mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)	C00003491
5605	MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2	mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)	C00003491
9020	MAP3K14, FTDCR1B, HS, HSNIK, NIK	mitogen-activated protein kinase kinase kinase 14 (EC:2.7.11.25)	C00003491
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00003491
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00003491
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00003491
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00003491
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00003491
9261	MAPKAPK2, MAPKAP-K2, MK-2, MK2	mitogen-activated protein kinase-activated protein kinase 2 (EC:2.7.11.1)	C00003491
4153	MBL2, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD	mannose-binding lectin (protein C) 2, soluble	C00003491
4223	MEOX2, GAX, MOX2	mesenchyme homeobox 2	C00003491
10461	MERTK, MER, RP38, c-mer	c-mer proto-oncogene tyrosine kinase (EC:2.7.10.1)	C00003491
4255	MGMT	O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63)	C00003491
8569	MKNK1, MNK1	MAP kinase interacting serine/threonine kinase 1 (EC:2.7.11.1)	C00003491
4311	MME, CALLA, CD10, NEP, SFE	membrane metallo-endopeptidase (EC:3.4.24.11)	C00003491
4312	MMP1, CLG, CLGN	matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7)	C00003491
4322	MMP13, CLG3, MANDP1	matrix metallopeptidase 13 (collagenase 3) (EC:3.4.24.-)	C00003491
4323	MMP14, MMP-14, MMP-X1, MT-MMP, MT-MMP_1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS	matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80)	C00003491
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00003491
118856	MMP21, MMP-21	matrix metallopeptidase 21	C00003491
4314	MMP3, CHDS6, MMP-3, SL-1, STMY, STMY1, STR1	matrix metallopeptidase 3 (stromelysin 1, progelatinase) (EC:3.4.24.17)	C00003491
4317	MMP8, CLG1, HNC, MMP-8, PMNL-CL	matrix metallopeptidase 8 (neutrophil collagenase) (EC:3.4.24.34)	C00003491
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00003491
4353	MPO	myeloperoxidase (EC:1.11.2.2)	C00003491
10232	MSLN, MPF, SMRP	mesothelin	C00003491
4481	MSR1, CD204, SCARA1, SR-A, SRA, phSR1, phSR2	macrophage scavenger receptor 1	C00003491
4502	MT2A, MT2	metallothionein 2A	C00003491
4582	MUC1, CA_15-3, CD227, EMA, H23AG, KL-6, MAM6, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM	mucin 1, cell surface associated	C00003491
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00003491
7593	MZF1, MZF-1, MZF1B, ZFP98, ZNF42, ZSCAN6	myeloid zinc finger 1	C00003491
4675	NAP1L3, MB20, NPL3	nucleosome assembly protein 1-like 3	C00003491
24142	NAT6, FUS-2, FUS2	N-acetyltransferase 6 (GCN5-related) (EC:2.3.1.-)	C00003491
64151	NCAPG, CAPG, CHCG, NY-MEL-3	non-SMC condensin I complex, subunit G	C00003491
653361	NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox	neutrophil cytosolic factor 1	C00003491
4688	NCF2, NCF-2, NOXA2, P67-PHOX, P67PHOX	neutrophil cytosolic factor 2	C00003491
4751	NEK2, HsPK21, NEK2A, NLK1	NIMA-related kinase 2 (EC:2.7.11.1)	C00003491
4745	NELL1, IDH3GL, NRP1	NEL-like 1 (chicken)	C00003491
4772	NFATC1, NF-ATC, NFAT2, NFATc	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	C00003491
4773	NFATC2, NFAT1, NFATP	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	C00003491
4775	NFATC3, NFAT4, NFATX	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	C00003491
4776	NFATC4, NF-ATc4, NFAT3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	C00003491
4781	NFIB, CTF, HMGIC/NFIB, NF-I/B, NF1-B, NFI-B, NFI-RED, NFIB2, NFIB3	nuclear factor I/B	C00003491
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00003491
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00003491
4795	NFKBIL1, IKBL, LST1, NFKBIL	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1	C00003491
4818	NKG7, GIG1, GMP-17, p15-TIA-1	natural killer cell group 7 sequence	C00003491
9111	NMI	N-myc (and STAT) interactor	C00003491
9221	NOLC1, NOPP130, NOPP140, NS5ATP13, P130	nucleolar and coiled-body phosphoprotein 1	C00003491
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00003491
404036			C00003491
4854	NOTCH3, CADASIL, CASIL, IMF2	notch 3	C00003491
124056	NOXO1, P41NOX, P41NOXA, P41NOXB, P41NOXC, SH3PXD5, SNX28	NADPH oxidase organizer 1	C00003491
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00003491
4835	NQO2, DHQV, DIA6, NMOR2, QR2	NAD(P)H dehydrogenase, quinone 2 (EC:1.10.99.2)	C00003491
2908	NR3C1, GCCR, GCR, GR, GRL	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	C00003491
3164	NR4A1, GFRP1, HMR, N10, NAK-1, NGFIB, NP10, NUR77, TR3	nuclear receptor subfamily 4, group A, member 1	C00003491
4929	NR4A2, HZF-3, NOT, NURR1, RNR1, TINUR	nuclear receptor subfamily 4, group A, member 2	C00003491
8013	NR4A3, CHN, CSMF, MINOR, NOR1, TEC	nuclear receptor subfamily 4, group A, member 3	C00003491
2494	NR5A2, B1F, B1F2, CPF, FTF, FTZ-F1, FTZ-F1beta, LRH-1, LRH1, hB1F-2	nuclear receptor subfamily 5, group A, member 2	C00003491
51203	NUSAP1, ANKT, BM037, LNP, NUSAP, PRO0310p1, Q0310, SAPL	nucleolar and spindle associated protein 1	C00003491
4953	ODC1, ODC	ornithine decarboxylase 1 (EC:4.1.1.17)	C00003491
4988	OPRM1, LMOR, M-OR-1, MOP, MOR, MOR1, OPRM	opioid receptor, mu 1	C00003491
5063	PAK3, CDKN1A, MRX30, MRX47, OPHN3, PAK3beta, bPAK, hPAK3	p21 protein (Cdc42/Rac)-activated kinase 3 (EC:2.7.11.1)	C00003491
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00003491
10038	PARP2, ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2	poly (ADP-ribose) polymerase 2 (EC:2.4.2.30)	C00003491
55872	PBK, CT84, Nori-3, SPK, TOPK	PDZ binding kinase (EC:2.7.12.2)	C00003491
56146	PCDHA2, PCDH-ALPHA2	protocadherin alpha 2	C00003491
5118	PCOLCE, PCPE, PCPE-1, PCPE1	procollagen C-endopeptidase enhancer	C00003491
27250	PDCD4, H731	programmed cell death 4 (neoplastic transformation inhibitor)	C00003491
5154	PDGFA, PDGF-A, PDGF1	platelet-derived growth factor alpha polypeptide	C00003491
5155	PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis	platelet-derived growth factor beta polypeptide	C00003491
5241	PGR, NR3C3, PR	progesterone receptor	C00003491
5300	PIN1, DOD, UBL5	peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (EC:5.2.1.8)	C00003491
5320	PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2	phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4)	C00003491
5327	PLAT, T-PA, TPA	plasminogen activator, tissue (EC:3.4.21.68)	C00003491
5328	PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA	plasminogen activator, urokinase (EC:3.4.21.73)	C00003491
5330	PLCB2, PLC-beta-2	phospholipase C, beta 2 (EC:3.1.4.11)	C00003491
5338	PLD2	phospholipase D2 (EC:3.1.4.4)	C00003491
5347	PLK1, PLK, STPK13	polo-like kinase 1 (EC:2.7.11.21)	C00003491
8228	PNPLA4, DXS1283E, GS2, iPLA2eta	patatin-like phospholipase domain containing 4 (EC:3.1.1.3)	C00003491
5427	POLE2, DPE2	polymerase (DNA directed), epsilon 2, accessory subunit (EC:2.7.7.7)	C00003491
5451	POU2F1, OCT1, OTF1, oct-1B	POU class 2 homeobox 1	C00003491
5452	POU2F2, OCT2, OTF2, Oct-2	POU class 2 homeobox 2	C00003491
5459	POU4F3, BRN3C, DFNA15	POU class 4 homeobox 3	C00003491
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00003491
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00003491
5473	PPBP, B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	C00003491
5578	PRKCA, AAG6, PKC-alpha, PKCA, PRKACA	protein kinase C, alpha (EC:2.7.11.13)	C00003491
5579	PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2	protein kinase C, beta (EC:2.7.11.13)	C00003491
5580	PRKCD, MAY1, PKCD, nPKC-delta	protein kinase C, delta (EC:2.7.10.2 2.7.11.13)	C00003491
5581	PRKCE, PKCE, nPKC-epsilon	protein kinase C, epsilon (EC:2.7.11.13)	C00003491
5582	PRKCG, PKC-gamma, PKCC, PKCG, SCA14	protein kinase C, gamma (EC:2.7.11.13)	C00003491
5583	PRKCH, PKC-L, PKCL, PRKCL, nPKC-eta	protein kinase C, eta (EC:2.7.11.13)	C00003491
5584	PRKCI, DXS1179E, PKCI, nPKC-iota	protein kinase C, iota (EC:2.7.11.13)	C00003491
5588	PRKCQ, PRKCT, nPKC-theta	protein kinase C, theta (EC:2.7.11.13)	C00003491
5590	PRKCZ, PKC-ZETA, PKC2	protein kinase C, zeta (EC:2.7.11.13)	C00003491
5587	PRKD1, PKC-MU, PKCM, PKD, PRKCM	protein kinase D1 (EC:2.7.11.13)	C00003491
9536	PTGES, MGST-IV, MGST1-L1, MGST1L1, MPGES, PGES, PIG12, PP102, PP1294, TP53I12, mPGES-1	prostaglandin E synthase (EC:5.3.99.3)	C00003491
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00003491
5747	PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK	protein tyrosine kinase 2 (EC:2.7.10.2)	C00003491
5799	PTPRN2, IA-2beta, IAR, ICAAR, PTPRP, R-PTP-N2	protein tyrosine phosphatase, receptor type, N polypeptide 2 (EC:3.1.3.48)	C00003491
9232	PTTG1, EAP1, HPTTG, PTTG, TUTR1	pituitary tumor-transforming 1	C00003491
5806	PTX3, TNFAIP5, TSG-14	pentraxin 3, long	C00003491
5879	RAC1, Rac-1, TC-25, p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	C00003491
10635	RAD51AP1, PIR51	RAD51 associated protein 1	C00003491
5889	RAD51C, BROVCA3, FANCO, R51H3, RAD51L2	RAD51 paralog C	C00003491
8438	RAD54L, HR54, RAD54A, hHR54, hRAD54	RAD54-like (S. cerevisiae)	C00003491
5914	RARA, NR1B1, RAR	retinoic acid receptor, alpha	C00003491
5918	RARRES1, LXNL, TIG1	retinoic acid receptor responder (tazarotene induced) 1	C00003491
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00003491
5932	RBBP8, COM1, CTIP, JWDS, RIM, SAE2, SCKL2	retinoblastoma binding protein 8	C00003491
9978	RBX1, BA554C12.1, RNF75, ROC1	ring-box 1, E3 ubiquitin protein ligase	C00003491
5966	REL, C-Rel	v-rel avian reticuloendotheliosis viral oncogene homolog	C00003491
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00003491
5984	RFC4, A1, RFC37	replication factor C (activator 1) 4, 37kDa	C00003491
5985	RFC5, RFC36	replication factor C (activator 1) 5, 36.5kDa	C00003491
28984	RGCC, C13orf15, RGC-32, RGC32, bA157L14.2	regulator of cell cycle	C00003491
8786	RGS11, RS11	regulator of G-protein signaling 11	C00003491
6003	RGS13	regulator of G-protein signaling 13	C00003491
391	RHOG, ARHG	ras homolog family member G	C00003491
8635	RNASET2, RNASE6PL, bA514O12.3	ribonuclease T2 (EC:3.1.27.1)	C00003491
6194	RPS6, S6	ribosomal protein S6	C00003491
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00003491
6279	S100A8, 60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF, P8	S100 calcium binding protein A8	C00003491
6280	S100A9, 60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG, MAC387, MIF, MRP14, NIF, P14	S100 calcium binding protein A9	C00003491
6286	S100P, MIG9	S100 calcium binding protein P	C00003491
9092	SART1, Ara1, HOMS1, SART1259, SNRNP110, Snu66	squamous cell carcinoma antigen recognized by T cells	C00003491
6382	SDC1, CD138, SDC, SYND1, syndecan	syndecan 1	C00003491
6385	SDC4, SYND4	syndecan 4	C00003491
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00003491
5055	SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	C00003491
5272	SERPINB9, CAP-3, CAP3, PI-9, PI9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	C00003491
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00003491
10262	SF3B4, AFD1, Hsh49, SAP49, SF3b49	splicing factor 3b, subunit 4, 49kDa	C00003491
22941	SHANK2, AUTS17, CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3	SH3 and multiple ankyrin repeat domains 2	C00003491
6464	SHC1, SHC, SHCA	SHC (Src homology 2 domain containing) transforming protein 1	C00003491
7979	SHFM1, DSS1, ECD, SEM1, SHFD1, SHSF1, Shfdg1	split hand/foot malformation (ectrodactyly) type 1	C00003491
946	SIGLEC6, CD327, CD33L, CD33L1, CD33L2, CDW327, OBBP1	sialic acid binding Ig-like lectin 6	C00003491
6503	SLA, SLA1, SLAP	Src-like-adaptor	C00003491
6520	SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE	solute carrier family 3 (amino acid transporter heavy chain), member 2	C00003491
8884	SLC5A6, SMVT	solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6	C00003491
6531	SLC6A3, DAT, DAT1, PKDYS	solute carrier family 6 (neurotransmitter transporter), member 3	C00003491
23657	SLC7A11, CCBR1, xCT	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	C00003491
10051	SMC4, CAP-C, CAPC, SMC-4, SMC4L1, hCAP-C	structural maintenance of chromosomes 4	C00003491
8835	SOCS2, CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2	suppressor of cytokine signaling 2	C00003491
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00003491
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00003491
6667	SP1	Sp1 transcription factor	C00003491
10615	SPAG5, DEEPEST, MAP126, hMAP126	sperm associated antigen 5	C00003491
6688	SPI1, OF, PU.1, SFPI1, SPI-1, SPI-A	spleen focus forming virus (SFFV) proviral integration oncogene	C00003491
6696	SPP1, BNSP, BSPI, ETA-1, OPN	secreted phosphoprotein 1	C00003491
6698	SPRR1A, SPRK	small proline-rich protein 1A	C00003491
6699	SPRR1B, CORNIFIN, GADD33, SPRR1	small proline-rich protein 1B	C00003491
6700	SPRR2A	small proline-rich protein 2A	C00003491
6734	SRPR, DP, Sralpha	signal recognition particle receptor (docking protein)	C00003491
10492	SYNCRIP, GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q	synaptotagmin binding, cytoplasmic RNA interacting protein	C00003491
8148	TAF15, Npl3, RBP56, TAF2N, TAFII68	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa	C00003491
6876	TAGLN, SM22, SMCC, TAGLN1, WS3-10	transgelin	C00003491
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00003491
7037	TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90	transferrin receptor	C00003491
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00003491
7042	TGFB2, LDS4, TGF-beta2	transforming growth factor, beta 2	C00003491
7051	TGM1, ARCI1, ICR2, KTG, LI, LI1, TGASE, TGK	transglutaminase 1 (EC:2.3.2.13)	C00003491
7066	THPO, MGDF, MKCSF, ML, MPLLG, THCYT1, TPO	thrombopoietin	C00003491
10440	TIMM17A, TIM17, TIM17A	translocase of inner mitochondrial membrane 17 homolog A (yeast)	C00003491
7076	TIMP1, CLGI, EPA, EPO, HCI, TIMP	TIMP metallopeptidase inhibitor 1	C00003491
7077	TIMP2, CSC-21K, DDC8	TIMP metallopeptidase inhibitor 2	C00003491
10333	TLR6, CD286	toll-like receptor 6	C00003491
3371	TNC, 150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C	tenascin C	C00003491
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00003491
7128	TNFAIP3, A20, OTUD7C, TNFA1P2	tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12)	C00003491
7132	TNFRSF1A, CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60	tumor necrosis factor receptor superfamily, member 1A	C00003491
7133	TNFRSF1B, CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR	tumor necrosis factor receptor superfamily, member 1B	C00003491
3604	TNFRSF9, 4-1BB, CD137, CDw137, ILA	tumor necrosis factor receptor superfamily, member 9	C00003491
8743	TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL	tumor necrosis factor (ligand) superfamily, member 10	C00003491
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00003491
7163	TPD52, D52, N8L, PC-1, PrLZ, hD52	tumor protein D52	C00003491
22974	TPX2, C20orf1, C20orf2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA519, HCTP4, REPP86, p100	TPX2, microtubule-associated	C00003491
7185	TRAF1, EBI6, MGC:10353	TNF receptor-associated factor 1	C00003491
6967			C00003491
29953	TRHDE, PAP-II, PGPEP2, TRH-DE	thyrotropin-releasing hormone degrading enzyme (EC:3.4.19.6)	C00003491
28951	TRIB2, C5FW, GS3955, TRB2	tribbles pseudokinase 2	C00003491
7442	TRPV1, VR1	transient receptor potential cation channel, subfamily V, member 1	C00003491
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00003491
1890	TYMP, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF	thymidine phosphorylase (EC:2.4.2.4)	C00003491
7298	TYMS, HST422, TMS, TS	thymidylate synthetase (EC:2.1.1.45)	C00003491
7305	TYROBP, DAP12, KARAP, PLOSL	TYRO protein tyrosine kinase binding protein	C00003491
29128	UHRF1, ICBP90, Np95, RNF106, hNP95, hUHRF1	ubiquitin-like with PHD and ring finger domains 1 (EC:6.3.2.19)	C00003491
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00003491
7421	VDR, NR1I1	vitamin D (1,25- dihydroxyvitamin D3) receptor	C00003491
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00003491
7431	VIM, CTRCT30	vimentin	C00003491
7434	VIPR2, C16DUPq36.3, DUP7q36.3, PACAP-R-3, PACAP-R3, VIP-R-2, VPAC2, VPAC2R, VPCAP2R	vasoactive intestinal peptide receptor 2	C00003491
6935	ZEB1, AREB6, BZP, DELTAEF1, FECD6, NIL2A, PPCD3, TCF8, ZFHEP, ZFHX1A	zinc finger E-box binding homeobox 1	C00003491
9839	ZEB2, HSPC082, SIP-1, SIP1, SMADIP1, ZFHX1B	zinc finger E-box binding homeobox 2	C00003491
9310	ZNF235, ANF270, HZF6, ZFP93, ZNF270	zinc finger protein 235	C00003491
113835	ZNF257, BMZF-4, BMZF4	zinc finger protein 257	C00003491
11130	ZWINT, HZwint-1, KNTC2AP, ZWINT1	ZW10 interacting kinetochore protein	C00003491

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