| class name | count |
|---|
| class name | count |
|---|---|
| Streptomycetaceae | 5 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00015930
|
Aclidinomycin A
|
|
||||
|
C00015931
|
Aclidinomycin B
/ (+)-Aclidinomycin B |
|
||||
|
C00016428
|
31F508b1
/ Bioxalomycin beta1 / Antibiotic 31F508b1 |
|
||||
|
C00016429
|
31F508b2
/ Bioxalomycin beta2 / Antibiotic 31F508b2 / Naphthyridinomycin A |
|
||||
|
C00018432
|
NSC 349644
/ Cyanocycline A / (+)-Cyanocycline A / Cyanonaphthyridinomycin |
CHEMBL520550
CHEMBL1727019 |
C035070
|
9 / 12 / 7 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | C00018432 | 1 / 1 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00018432 | 0 / 0 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00018432 | 1 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00018432 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00018432 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00018432 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00018432 | 7 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00018432 | 0 / 0 |
| Q06710 | Paired box protein Pax-8 | Unclassified protein | C00018432 | 1 / 2 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #300615 | Brunner syndrome |
P21397
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #218700 | Hypothyroidism, congenital, nongoitrous, 2; chng2 |
Q06710
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| KEGG | name | UniProt |
|---|---|---|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00032 | Thyroid cancer |
Q06710
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
Q06710
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|