KCF-S cluster No. 2130 (5 metabolites)

Corresponding Phytochemical cluster No. 51

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (5)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	6

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Cumulative family count

class name	count
Simaroubaceae	6

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Dammarenes	5

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metabolites link (5)

br08003 Category	KEGG ID	KNApSAcK ID
Dammarenes	C08749	C00003699
Dammarenes	C08750	C00003700
Dammarenes	C08751	C00003701
Dammarenes	C08754	C00003704
Dammarenes	C08782	C00003730

Metabolite list (5)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00003699	Bruceantin	CHEMBL509895 CHEMBL1700569	C002550	12 / 12 / 8	0 / 1
C00003700	Bruceantinol	CHEMBL450145
C00003701	Bruceine B	CHEMBL140809	C024965
C00003704	Brusatol	CHEMBL450464 CHEMBL1702665	C020237	9 / 15 / 8	2 / 0
C00003730	Sergeolide	CHEMBL521373 CHEMBL1975433	C045844	1 / 0 / 0

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P05412	Transcription factor AP-1	Transcription Factor	C00003699 C00003704 C00003730	0 / 0
O75496	Geminin	Unclassified protein	C00003699 C00003704	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003699 C00003704	2 / 0
P37840	Alpha-synuclein	Unclassified protein	C00003699 C00003704	4 / 2
Q06710	Paired box protein Pax-8	Unclassified protein	C00003699 C00003704	1 / 2
Q99700	Ataxin-2	Unclassified protein	C00003699 C00003704	1 / 1
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00003699 C00003704	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00003699 C00003704	0 / 0
P11308	Transcriptional regulator ERG	Unclassified protein	C00003699	1 / 2
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00003704	7 / 3
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00003699	1 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003699	1 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00003699	1 / 1

2 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
9817	KEAP1, INrf2, KLHL19	kelch-like ECH-associated protein 1	C00003704
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00003704

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions