class name | count |
---|
class name | count |
---|---|
Dermateaceae | 4 |
Pleosporaceae | 1 |
br08003 Category | # of metabolite |
---|
br08003 Category | KEGG ID | KNApSAcK ID |
---|
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
---|---|---|---|---|---|---|
C00016325
![]() |
F 10863A
/ Zaragozic acid D3 / Squalene synthase inhibitor compd. A |
![]() |
||||
C00016326
![]() |
F 10863B
|
![]() |
||||
C00016327
![]() |
F 10863C
|
![]() |
||||
C00016328
![]() |
F 10863D
|
![]() |
||||
C00016820
![]() |
L 694599
/ GR 105155X / Squalestatin / Squalestatin 1 / Squalestatin S1 / Zaragozic acid A |
CHEMBL280978
CHEMBL40991 CHEMBL302601 CHEMBL86319 CHEMBL434998 CHEMBL1477148 CHEMBL1886451 |
C075117
|
8 / 11 / 9 |
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accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P37268 | Squalene synthase | Enzyme | C00016820 | 0 / 0 |
P54132 | Bloom syndrome protein | Enzyme | C00016820 | 1 / 2 |
P11473 | Vitamin D3 receptor | NR1I1 | C00016820 | 2 / 3 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00016820 | 0 / 0 |
P31749 | RAC-alpha serine/threonine-protein kinase | Akt | C00016820 | 4 / 1 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00016820 | 0 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00016820 | 4 / 3 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00016820 | 0 / 0 |
OMIM | preferred title | UniProt |
---|---|---|
#210900 | Bloom syndrome; blm |
P54132
|
#114480 | Breast cancer |
P31749
|
#114500 | Colorectal cancer; crc |
P31749
|
#615109 | Cowden syndrome 6; cws6 |
P31749
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#176920 | Proteus syndrome |
P31749
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG | name | UniProt |
---|---|---|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00342 | Tuberculosis |
P11473
(related)
|
H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
H00539 | PTEN hamartoma tumor syndrome (PHTS) |
P31749
(related)
|
H00094 | DNA repair defects |
P54132
(related)
|
H00296 | Defects in RecQ helicases |
P54132
(related)
|